ライフサイエンスコーパス: microbiome

1 patients with PSC harbor an abnormal enteric microbiome.

2 weakly associated with variation in the gut microbiome.

3 Exercise modulates metabolism and the gut microbiome.

4 acteroidetes, the dominant phylum of the gut microbiome.

5 ria that are asymptomatically colonizing the microbiome.

6 s and Test diet altered the fecal metabolome/microbiome.

7 ng ecological and evolutionary forces in the microbiome.

8 ntestinal amino acid homeostasis and the gut microbiome.

9 to a reduction of bacteria important for the microbiome.

10 inked individually to alterations in the gut microbiome.

11 7/IL-22, with concomitant changes in the gut microbiome.

12 sal primes, significantly altered the rectal microbiome.

13 nged by the metabolic activities of the oral microbiome.

14 bly processes structuring the amphibian skin microbiome.

15 iver function, hepatic steatosis and the gut microbiome.

16 om metagenomes from the infant and adult gut microbiome.

17 onor bacteria that are part of the mammalian microbiome.

18 redispose chorioretinitis via an altered gut microbiome.

19 involved in apoptosis and stress response to microbiomes.

20 nown whether Kac level is altered in patient microbiomes.

21 ponica, a putative producer abundant in crop microbiomes.

22 DNA viruses that are prevalent in human gut microbiomes.

23 exclusion, shapes the architecture of these microbiomes.

24 lammatory disease in mice harboring distinct microbiomes.

25 ortance to reveal functional interactions in microbiomes.

26 liver sinusoidal endothelial cells sense the microbiome, actively orchestrating the localization of i

27 ntil now, the mediators derived from the gut microbiome affecting the gut-immune-brain axis and the m

28 The composition of the intestinal microbiome affects health from the prenatal period throu

29 faecal AMR gene abundance and diversity and microbiome alpha diversity.

30 s encode ~30 amyloidogenic proteins, the gut microbiome also produces functional amyloids.

31 Gut microbiome alterations correlated with model for end-sta

32 Alteration of the microbiome alters TLR7-MyD88 signaling in plasmacytoid d

33 re studies should consider MSM status in gut microbiome analyses.

34 Microbiome analysis in both AS and AS + Ck culture sampl

35 To address some of these challenges, microbiome analysis workflows often normalize the read c

36 bes in a sample, is a critical first step in microbiome analysis.

37 e association between the infant/toddler gut microbiome and ASD-related social behaviors at age 3 yea

38 have revealed important associations between microbiome and disease/health status.

39 Connections between the microbiome and health are rapidly emerging in a wide ran

40 Analysis of VOCs can reflect both the microbiome and host response to a condition.

41 model to test diets that favorably alter the microbiome and improve host intestinal health in both pi

42 teman shows that herbivory reshapes the leaf microbiome and increases susceptibility to potential bac

43 Our aim was to investigate the COPD sputum microbiome and its association with inflammatory phenoty

44 predictive capacity of the gastrointestinal microbiome and its relationship to infectious outcomes i

45 enhance our understanding of the kogiid gut microbiome and may provide useful information for symbio

46 esults revealed an overall alteration in gut microbiome and metabolites in association with SE infect

47 eds for tools that can effectively integrate microbiome and metabolome data to derive biological insi

48 In this study, an automated microbiome and metabolome integrative analysis pipeline

49 Motivated by microbiome and metagenomics studies, where the data are

50 coronavirus disease 19 infection on the gut microbiome and on the gut epithelium.

51 The roles of ageing, sex, the gut microbiome and organ transplantation in this complex int

52 ted States, were surveyed for host immunity, microbiome and pathogen dynamics.

53 sory pain, but any relationships between gut microbiome and PN in obesity have yet to be explored.

54 -2 were used to determine the effects of the microbiome and quorum-sensing molecules on depressive-li

55 oduce favorable changes in the commensal gut microbiome and reduce host vulnerability to stress-induc

56 environments on temporal changes in the gut microbiome and resistome of veterinary students with occ

57 emonstrated the complexity of the root canal microbiome and the "common denominators" of root canal i

58 have investigated the link between the oral microbiome and these cancers.

59 s issue, we carried out deep analysis of the microbiome and transcriptome in the skin of a large coho

60 a mucosal SIV vaccine regimen on the rectal microbiome and validates our previously reported SIV vac

61 Bacteriodes and Fusobacterium dominated the microbiome and were positively correlated across all pop

62 ding the provision of passive immunity and a microbiome and, in humans, the psychosocial benefits of

63 dicting the impact of climate change on soil microbiomes and the ecosystem services they provide pres

64 t on persistent gut symptoms, the intestinal microbiome, and circulating markers of inflammation in p

65 Physiological, microbiome, and clinical results were not robustly relat

66 least in part, dependent on formation of the microbiome, and consequently contributed to the developm

67 ndotypes-mainly characterized by RV species, microbiome, and type 2 cytokine (T2) response: endotype

68 The altered colon microbiome approximated clinical findings in PD patients

69 Sex and the microbiome are critical factors that should not be overl

70 Lifestyle, obesity, and the gut microbiome are important risk factors for metabolic diso

71 Internal microbiomes are predominantly associated with top-down e

72 s analysis, we found a rapid increase in gut microbiome ARG richness and abundance in women from 2 in

73 pment of novel strategies to restructure the microbiome as a means of preventing or treating diseases

74 Prior works that have examined the gut microbiome as a novel biomarker for advanced fibrosis ha

75 Arabidopsis thaliana contribute to the plant microbiome assembly.

76 through animal models and human studies with microbiome assessment after ASD presentation.

77 Microbiome-associated histidine and tyrosine metabolites

78 Recent microbiome association studies have revealed important a

79 esults suggest that previously reported oral microbiome associations are observable in a human popula

80 minant seasonal effect on the drinking water microbiomes at all three locations.

81 Furthermore, the biofilm microbiomes at electrodes were studied using the PacBio

82 micals, ultimately influencing the brain-gut-microbiome axis of their host, a bidirectional communica

83 ism), a framework to translate the deluge of microbiome-based genomic information into a catalog of m

84 nical course of IBD, and strategies by which microbiome-based therapies can be used to prevent, manag

85 ples from responders had higher diversity of microbiomes before administration of donor material than

86 physiology over time, including genomes, gut microbiomes, blood metabolomes, blood proteomes, clinica

87 (probiotic and prebiotic) altered the fecal microbiome but did not reduce liver fat content or marke

88 o infection was not associated with baseline microbiome but was reproduced in mice by preinfection ch

89 investigated the involvement of the animal's microbiome, but little is known about the host's actual

90 rs now recognize the importance of the coral microbiome, but they often overlook other species that l

91 Targeting the gut microbiome, butyrate, and its consequences may represent

92 Manipulation of the gut microbiome by transplantation and cohousing demonstrated

93 t-based therapy to induce changes in the gut microbiome can alter systemic alloimmunity in mice, in p

94 ese data show how a member of the human skin microbiome can be useful as a biotherapy for acne vulgar

95 Ds that investigate how manipulations of the microbiome causally impact the development of behavioral

96 Although microbiome changes followed more linear trends over time

97 ce host and disease phenotype, compositional microbiome changes, which have been demonstrated in pati

98 duction of antimicrobial peptides and caused microbiome changes.

99 Whether microbiome characteristics of induced sputum or oral sam

100 age-related diseases may lie in how the gut microbiome communicates with both the intestinal mucosa

101 ough they may not play a significant role in microbiome communities, they could serve as opportunisti

102 We observe significant differences in gut microbiome composition across populations that correlate

103 nts and metals would correlate with salivary microbiome composition and be associated with dental dec

104 We observed that the microbiome composition and functional potential were con

105 Changes in fecal microbiome composition and metabolites were associated w

106 standing of how the taxonomic and functional microbiome composition and the resulting ecological inte

107 Microbiome composition showed weak associations with men

108 ied developmental trajectories of early-life microbiome composition, as well as predominant bacteria

109 ve Desert and assessed relationships between microbiome composition, environmental variation, geograp

110 ood approximation of the average gut mucosal microbiome composition, mucosal biopsies allowed detecti

111 ed animals showed decreased diversity of gut microbiome composition, while the ART group appeared to

112 ic islet cell mass, neuronal innervation and microbiome composition.

113 Late succession microbiomes conferred the strongest herbivore resistance

114 We demonstrate that the intestinal microbiome contributes to cholestasis-mediated cell deat

115 altered immunity, the biogeography of immune-microbiome correlations among HEU children have not been

116 The accuracy and reproducibility of microbiome data depend on sample integrity, which can be

117 ion, these findings establish a key role for microbiome-dependent circadian GLP-1 secretion in the ma

118 trimethylamine N-oxide (TMAO), an intestinal microbiome-dependent metabolite, worsens graft-versus-ho

119 ne reactivity to allergens, autoantigens and microbiome determinants.

120 Early life microbiome development trains immune function.

121 Our findings define unique microbiome differences after chronic versus acute viral

122 We here assess microbiome differences in a larger cohort of human subje

123 We identified a microbiome disease response shared across multiple disea

124 No association was observed between microbiome diversity and CD4+ T-cell count, HIV viral lo

125 mposition); however, in the absence of clear microbiome-driven effects, caution is needed in interpre

126 shown, consistent with postulated permissive microbiome driving CA lesion genesis via lipopolysacchar

127 ; we investigate how differences in the soil microbiome due to antecedent soil treatment additionally

128 ome in early life and the composition of the microbiome during illnesses were related to risk of chil

129 published longitudinal dataset studying the microbiome during pregnancy.

130 emotional dysregulation and alcohol-related microbiome dysbiosis could accelerate the cycle of addic

131 ns between global trends in land use change, microbiome dysbiosis, and wildlife disease.

132 expanding taxa as potential mediators of gut microbiome dysbiosis.

133 d functional metagenomic screens to identify microbiome-encoded genes responsible for specific metabo

134 Microbiome end points included SER-287 engraftment (dose

135 ment, but few studies have explored cetacean microbiomes especially deep divers.

136 Exploratory analyses of the microbiome failed to reveal possible responder compared

137 They define a core genitourinary microbiome for older women with many heritable microbial

138 sting of 1116 fecal metabolites and 16s rRNA microbiome from 786 individuals.

139 erum was optimal for replicating subgingival microbiomes from health and disease.

140 were more similar to each other than to oral microbiomes from non-related individuals.

141 e further evaluated transmissibility of oral microbiomes from parents and during cohousing experiment

142 Additionally, oral microbiomes from participants of the same family were mo

143 However, the ecological relevance of this microbiome-gut-brain (MGB) axis outside the laboratory r

144 upting neural programming and/or through the microbiome-gut-brain axis.

145 Our results suggest that the microbiome-gut-immune axis can be modified by DEHP and e

146 Diet and microbiome had the strongest predictive power, and each

147 obiome(mixed)T2(low); endotype B, virus(RV-A)microbiome(Haemophilus)T2(low); endotype C, virus(RSV/RV

148 The sputum microbiome has a potential role in disease phenotyping a

149 The gut microbiome has been causally implicated in many immune-m

150 s ago, but the characterization of the tumor microbiome has remained challenging because of its low b

151 While the taxonomic diversity of their microbiomes has been well-established for corals and spo

152 Changes in the intestinal microbiome have been associated with obesity and type 2

153 Pathologic changes to the gut microbiome have recently been linked to somatosensory pa

154 Uninfected human patients and ferret URT microbiomes have stable healthy ecostate communities bot

155 a better understanding of the intricacies of microbiome-host interactions (clinicaltrials.gov trial N

156 the value of multiomics approaches to study microbiome-host interactions following chemical perturba

157 he concept of the 'nidobiome', a new unit of microbiome-host interactions, which brings together thes

158 indicative of the least exposure to maternal microbiome (ie no labour, short interval between membran

159 from the IBD cohort of the integrative human microbiome (iHMP-IBD) project.

160 hlight nutritional features that modulate SI microbiome, immunity, and barrier function and identify

161 rences in both innate immunity and the stool microbiome in a biogeographical population-specific way.

162 The role of the intestinal microbiome in alcoholic hepatitis is not established.

163 lopmental trajectories of the nasopharyngeal microbiome in early life and the composition of the micr

164 out exercise, on systemic metabolism and gut microbiome in four groups of mice: (a) no intervention;

165 inconsistent pleiotropic effects on the leaf microbiome in maize.

166 es is a major route for establishing the gut microbiome in newborns.

167 We investigated the gut microbiome in patients with cirrhosis encompassing the w

168 s usually preceded by disruption of the host microbiome in response to antibiotic treatment and is ch

169 the filter media and its relationship to the microbiome in the filter effluent water.

170 tories identified, a Staphylococcus-dominant microbiome in the first 6 months of life was associated

171 We evaluated the soil microbiome in the inocula and after chrysanthemum growth

172 o promote liver injury in the absence of the microbiome in vivo.

173 erize the healthy salivary and dental plaque microbiome in young children.

174 ely little is known about the role of sponge microbiomes in the Antarctic marine environment, where s

175 s tumor recurrence, including changes in the microbiome, in mice that underwent colorectal resection.

176 'Dysbiosis' of the maternal gut microbiome, in response to challenges such as infection(

177 ociations between elements of the intestinal microbiome (including specific microbes, signaling pathw

178 The host-associated microbiome, including the oral microbiome, presents itse

179 s characterized by biofilm-forming and human-microbiome-influenced environments with corresponding pa

180 In mice, the maternal microbiome influences fetal immune development and postn

181 n important enterohepatic axis of metabolite-microbiome interaction resulting in maintenance of metab

182 the consequences of these compounds for host-microbiome interactions remain unknown.

183 ly recognized as important factors in animal-microbiome interactions: for example, by providing the h

184 ohousing demonstrated that transfer of these microbiomes into genetically identical hosts was suffici

185 The human gut microbiome is a collection of bacteria, protozoa, fungi,

186 Restoration of the gut microbiome is a promising preventive and therapeutic str

187 The microbiome is an assemblage of microorganisms living in

188 The sputum microbiome is associated with clinical and inflammatory

189 The urinary microbiome is distinct from nearby sites and unrelated t

190 The microbiome is dysbiotic and heterogeneous in both diseas

191 And although the gut microbiome is influenced by HIV infection and may contri

192 Studies have demonstrated that the gut microbiome is linked to metabolic health and its alterat

193 The oral microbiome is one of the most stable ecosystems in the b

194 Our emerging view of the gut microbiome largely focuses on bacteria, while less is kn

195 etabolism in intestinal epithelial cells and microbiome, leading to increased lactate production.

196 no studies have examined protein Kac at the microbiome level, and it remains unknown whether Kac lev

197 Interventions targeting the gut microbiome may be warranted to reduce cardiovascular ris

198 Conversely, rhizosphere microbiome members with growth-promotive siderophores we

199 Microbiome/metagenomic data have specific characteristic

200 alyzing processed multilevel or longitudinal microbiome/metagenomic data.

201 Many microbiome/metagenomic studies follow a longitudinal des

202 ed on these data, features of the intestinal microbiome might be used for CRC screening and modified

203 This microbiome might provide resistance against colonization

204 tokine (T2) response: endotype A, virus(RV-C)microbiome(mixed)T2(low); endotype B, virus(RV-A)microbi

205 tococcus)T2(low); and endotype D, virus(RV-C)microbiome(Moraxella)T2(high).

206 Here we propose an integrative microbiome neuro-immuno-affective framework of how emoti

207 The salivary microbiome of 4-y-old children is still distinct from th

208 Similar to humans, the fecal microbiome of dogs may be useful in diagnosing diseases

209 quencing to comprehensively characterise the microbiome of the common reef-building coral, Porites lu

210 g near-isogenic lines were compared with the microbiome of the disease-susceptible parent line at two

211 ffects of filter design and operation on the microbiome of the filter media and its relationship to t

212 upplementation interacts with the developing microbiome of the small intestine, the major site for nu

213 categories of the enzymes present in the gut microbiomes of each species.

214 e contributing to a significant shift in the microbiomes of juvenile oysters that reduces fitness and

215 Leveraging the microbiomes of marine animals and cutting-edge metabolom

216 However, the gut microbiomes of multiple unrelated healthy individuals as

217 Applying to the analyses of microbiomes of patients with Crohn's disease identifies

218 Bacterial and fungal leaf microbiomes of the resulting near-isogenic lines were co

219 he effect of variations within the human gut microbiome on drugs, has already provided important insi

220 t provide insights into the influence of the microbiome on the health of hematologic malignancy patie

221 limatic factors are stronger determinants of microbiomes on host external surfaces.

222 nmental factors (including the environmental microbiome) on disease dynamics, yet the importance of t

223 have been well-studied nutrients for the gut microbiome, other resources such as nucleic acids and nu

224 While developed to study the human microbiome, our software can be employed in various rese

225 in the fall and the shift to a more anti-Bd microbiome over winter as a preparatory response for sub

226 to show how interactions between host, host microbiome, pathogen, and the environment all affect dis

227 ynamics, yet the importance of the host-host microbiome-pathogen-environment interaction has been poo

228 Gut microbiomes perform crucial roles in host health and dev

229 our understanding of the important role the microbiome plays in aging and how this knowledge opens t

230 st-associated microbiome, including the oral microbiome, presents itself in a complex ecosystem impor

231 Gut microbiome profiles of 171 Asians with biopsy-proven NAF

232 of microbial biodiversity such as the Earth Microbiome Project (EMP) and the Human Microbiome Projec

233 Earth Microbiome Project (EMP) and the Human Microbiome Project (HMP) have revealed robust ecological

234 he prediabetes study of the Integrated Human Microbiome Project (iHMP).

235 Using Human Microbiome Project and Earth Microbiome Project data, we

236 Using Human Microbiome Project and Earth Microbiome Project data, we show that phylogenize draws

237 The stools were sequenced using Earth Microbiome project protocols and data were processed usi

238 her, our findings show that the maternal gut microbiome promotes fetal thalamocortical axonogenesis,

239 bolomic profiling revealed that the maternal microbiome regulates numerous small molecules in the mat

240 This raises the possibility for novel, microbiome-related therapeutic targets that may effectiv

241 The sinonasal microbiome remains poorly defined, with our current know

242 on performance, but their effect on the soil microbiome remains poorly understood.

243 The human microbiome represents a new frontier in understanding th

244 Concerns of poor study and microbiome reproducibility also abound in the literature

245 In this Review, we explore how plant microbiome research has unravelled the complex network o

246 Technical advances in the field of microbiome research have allowed for a better understand

247 High-quality microbiome research relies on the integrity, management

248 The next stage in plant microbiome research will require the integration of ecol

249 -expression networks to explore how the soil microbiome responded to changes in soil moisture and nut

250 The recent advances in microbiome science have highlighted the importance of in

251 Translational microbiome science in humans has not yet fully realized

252 Advances in microbiome science require a better understanding of how

253 tial roadmap for accelerating translation of microbiome science toward microbiome-targeted personaliz

254 junction dysregulation in IECs, promoted gut microbiome shifts and enhanced intestinal CD8 T cell res

255 cteria, whereas after treatment, responders' microbiomes showed increased Bacteroidia and Clostridia.

256 e gene profiles for each sample and compared microbiome signatures between the CTX-T and CTX-N infant

257 Microbiome signatures showed marked shifts in taxonomic

258 aemophilus)T2(low); endotype C, virus(RSV/RV)microbiome(Streptococcus)T2(low); and endotype D, virus(

259 ertook a comprehensive analysis of the tumor microbiome, studying 1526 tumors and their adjacent norm

260 Microbiome surveys are often used to identify potential

261 multiple NDs and consider the potential for microbiome-targeted interventions for NDs.

262 ing translation of microbiome science toward microbiome-targeted personalized treatments for FGIDs.

263 We identify candidate members of the gut microbiome that elicit a Smarcad1-dependent colitis resp

264 can be identified from taxa in the adult gut microbiome that have rarely been recognized for sideroph

265 uestion is whether we can select for a plant microbiome that is robust after colonization of target h

266 esults highlight that selecting for a stable microbiome that is well adapted to a particular host env

267 ding of the interaction of BAs with the host microbiome, their effect on innate and adaptive immunity

268 For leaf microbiomes, these results were supported by the observa

269 We tested whether optimizing the neonate's microbiome through maternal probiotic supplementation ca

270 the constant flow of metabolites used by the microbiome to alter reproduction and host behaviour.

271 oides difficile strains while preserving the microbiome to develop an efficacious agent.

272 y investigated the contribution of the fecal microbiome to influence host physiology in two Indigenou

273 erapeutics aimed at shaping a less dysbiotic microbiome to prevent or treat age-related diseases.

274 mproves cultivation-based surveys of diverse microbiomes to gain deeper insights into microbial funct

275 Of the 4 microbiome trajectories identified, a Staphylococcus-dom

276 Peptide treatment reprogrammed the microbiome transcriptome, suppressed the production of p

277 The neonatal gut microbiome undergoes dynamic changes in response to many

278 a range of factors associated with human gut microbiome variation.

279 We must also learn more about how the microbiome varies among apparently healthy people, how i

280 following the replenishment of youthful gut microbiome via modulation of immunologic, microbial, and

281 ces in urine and fecal metabolomes and fecal microbiome vs control individuals, independent of sympto

282 Altered gut microbiome was associated with complications of cirrhosi

283 In the second cycle, AS microbiome was enriched toward caproate production and s

284 s analyzed, the alpha-diversity of the fecal microbiome was unchanged among subjects after initiation

285 al oscillations of the 'dirty-cage/excrement microbiome', we ranked by priority the heterogeneity of

286 Using survey data of the human gut microbiome, we detected C. difficile colonization and bl

287 e genomic and transcriptomic components in a microbiome, we performed a meta-omic survey of extremoph

288 To characterize the upper airway microbiome, we used 16S ribosomal RNA and shotgun metage

289 reas associations between TMAO and the fecal microbiome were assessed by permutational multivariate A

290 Fe status, intestinal functionality and gut microbiome were observed between the short-term and long

291 Stool samples were collected, and microbiomes were analyzed by 16S rRNA gene sequencing.

292 Prior to treatment, participants' microbiomes were dissimilar from the RBX7455 composition

293 impact gene-centric analysis of human fecal microbiomes when using DIAMOND, an alignment tool that i

294 d intake modifies the composition of the gut microbiome, which contributes to the metabolism of flavo

295 nted, as have steroid hormone effects on the microbiome, which is known to influence mucosal immune r

296 tal studies of this natural ecosystem at the microbiome-wide scale are rare, and consequently we have

297 The human oral microbiome with its diverse habitats and abundant, relat

298 nct from nearby sites and unrelated to stool microbiome with more Actinobacteria, Fusobacteria and Pr

299 metabolites represents a mechanism by which microbiomes with beneficial effects on host growth could

300 eedback concept can be applied to steer soil microbiomes with the goal of inducing resistance above g