ライフサイエンスコーパス: microdroplet

1 act with the surface of a metastable aqueous microdroplet.

2 ve enough to detect a single nucleotide in a microdroplet.

3 diagram of thermally responsive IDPs within microdroplets.

4 sed for monitoring the growth of bacteria in microdroplets.

5 surface textures can be applied to transfer microdroplets.

6 chanisms that drive reaction acceleration in microdroplets.

7 in lipid-stabilized, phase-separated aqueous microdroplets.

8 r single cells encapsulated into an array of microdroplets.

9 assembly is greatly improved when using gel microdroplets.

10 ch impedes a more universal applicability of microdroplets.

11 f the internal configurations of LC emulsion microdroplets.

12 quence of approximately 40-600 encapsulating microdroplets.

13 to 5100 resulting from the stable QD-loaded microdroplets.

14 gregates and is contaminated by silicone oil microdroplets.

15 elopment of an enzyme assay inside picoliter microdroplets.

16 2-100 ng of protein was added to amino acid microdroplets.

17 ted for the first time in "optically sliced" microdroplets.

18 networks of lipid membranes through adhered microdroplets.

19 d into a phenyl carbocation (Ph(+)) in water microdroplets.

20 ility to the number concentrations of single microdroplets.

21 e impurities from the surface of heavy water microdroplets.

22 pressure of 120 psi to form ~10 mum diameter microdroplets.

23 n rate acceleration afforded by electrospray microdroplets.

24 pt cause a higher likelihood of silicone oil microdroplets.

25 tential for developing novel reactivities in microdroplets.

26 which soluble proteins aggregate into dense microdroplets.

27 copolymer molecules on biopolymer coacervate microdroplets.

28 le cells and reagents in independent aqueous microdroplets (1 pL to 10 nL volumes) dispersed in an im

29 ng the mixing dynamics of colliding airborne microdroplets (40 +/- 5 mum diameter) using a streak-bas

30 The coacervate microdroplets act as killer protocells for the obliterat

31 sed on the light-induced generation of water microdroplets acting as reversible stirrers of two conti

32 However, the unique environment of microdroplets allows different chemistry to occur.

33 aration (LLPS) of proteins into concentrated microdroplets (also called coacervation) is a phenomenon

34 The contrasting features of microdroplet and bulk-solution reactions are described t

35 y the degree of solute entrapment within the microdroplet and further describes the dynamics of dropl

36 dividual cells are encapsulated into aqueous microdroplets and assayed directly for the release of an

37 enables simultaneous creation of drug-laden microdroplets and encapsulation of stem cells in photopo

38 mprising a hybrid of fillers of liquid metal microdroplets and metallic magnetic microparticles.

39 The combined utilization of PDMS microdroplets and microspheres not only enables the real

40 community of protease-containing coacervate microdroplets and protein-polymer microcapsules (protein

41 the strand to be sequenced, are captured in microdroplets and read directly could have substantial a

42 roach by comparing sequencing results of gel microdroplets and single cells following MDA.

43 chemical reactions between the charged spray microdroplets and surface molecules can be exploited to

44 coefficients can be quantified using merged microdroplets and that merged droplets can be used to st

45 me the passive generation of salt-based ATPS microdroplets and their biocompatibility test.

46 reate a microlens based on the liquid sulfur microdroplets and tune its characteristics in real time

47 chnology-based device such as microfluidics, microdroplets, and microchamber.

48 small volumes such as intracellular fluids, microdroplets, and microfluidic chips also requires nano

49 tion and germination, plasmid stability, gel microdroplets, and the production of double-stranded RNA

50 ximately 23%) and suspended petroleum liquid microdroplets ( approximately 0.8%).

51 Therefore, the microdroplets are able to provide the contrast effects f

52 These printed colorimetric microdroplets are composed of a nonvolatile solvent so t

53 Complex coacervate microdroplets are finding increased utility in synthetic

54 RM images is achieved by applying a chemical microdroplet array to the sample surface which is used t

55 ning surface-wettability-guided assembly and microdroplet-array-based operations.

56 The device consists of four integrated microdroplet arrays, each hosting over 8000 docking site

57 mpatible, magnetically responsive ferrofluid microdroplets as local mechanical actuators and allows q

58 posed molecules detected by our enhanced gel microdroplet assay.

59 overcome this limitation, we have developed microdroplet assays enabling us to detect single primary

60 The charged microdroplets associated with incompletely dried ions co

61 t the ability of inkjet to precisely pattern microdroplets at high resolution to encode multiple stan

62 by leveraging LCM technology coupled to our microdroplet based sample preparation approach.

63 icrobial, and CNS-active agents, this simple microdroplet-based strategy for constructing such scaffo

64 bed from the surface are captured by charged microdroplets before entering a mass spectrometer.

65 Lengthened lifetimes were observed in water microdroplets but not in microdroplets composed of organ

66 these attributes through Raman excitation in microdroplets-but microdroplets have not been used in pr

67 Analysis of the collected microdroplets by NMR spectroscopy showed the presence of

68 emitter to control the reactivity of charged microdroplets by varying their exposure time with acid v

69 e have examined the same reaction in aqueous microdroplets (ca. 5 mum diameter) and find that the cyc

70 our results suggest that peptide-nucleotide microdroplets can be considered as a new type of protoce

71 EGaIn microdroplets can be incorporated into elastomers to fab

72 Using this module, microdroplets can be sorted based on absorbance readout

73 es (primary, secondary, and tertiary) in the microdroplets can react with both C(7)H(7)(+) and C(6)H(

74 solution and helps us further understand why microdroplet chemistry differs so markedly from bulk-pha

75 ally prepared Cu-MOFs, those synthesized via microdroplet chemistry exhibit comparable surface areas

76 Microdroplet chemistry is attracting increasing attentio

77 ively charged microbubble/positively charged microdroplet clusters are injected i.v., activated withi

78 Self-organized hexagonally patterned microdroplet clusters over locally heated water surfaces

79 influenced not only by the velocity at which microdroplets collide but also the geometry of the colli

80 ed entropy observed in chemical reactions in microdroplets compared to the same reaction conditions i

81 ound loaded with a lipophilic NIR dye to the microdroplet component was shown to facilitate local rel

82 e observed in water microdroplets but not in microdroplets composed of organic solvents.

83 he electric field energization of coacervate microdroplets comprising polylysine and short single str

84 urrent-time recordings of emulsified toluene microdroplets containing 20 mM Ferrocene (Fc), show elec

85 the encounter of 40 ppbv-6.0 ppmv O3(g) with microdroplets containing [catechol] = 1-150 muM.

86 dic channel in which were injected composite microdroplets containing a solution of an azidocoumarin

87 in biomass between populations of picoliter microdroplets containing different species of cyanobacte

88 itions, followed by flow cytometry to detect microdroplets containing microcolonies.

89 rystallization patterns (DCP) of an array of microdroplets containing solutions of different reporter

90 ng such superlattices that involves moulding microdroplets containing the nanoparticles and spatially

91 water surrounded by silicone oil where each microdroplet contains <1 enzyme on average.

92 ne-pot" disulfide reduction and digestion in microdroplets could occur simultaneously by spraying the

93 reaction is also undertaken at liquid metal microdroplets created via sonication to produce Ag- and

94 gement showed an increased product yield and microdroplet density, whilst avoiding any on-paper inter

95 Organic microdroplet deposits of DDPD in HDOP at basal plane pyr

96 Single microdroplets (diameter approximately 50 mum, 65 pL) fal

97 tark contrast to the observation that NH4NO3 microdroplets do not homogeneously effloresce, even when

98 posite net charges, self-assemble into dense microdroplets driven by weak molecular interactions.

99 duce that only a small number of the initial microdroplets effectively carry analyte molecules that u

100 -matter composite consisting of liquid metal microdroplets embedded in a soft elastomer matrix is pre

101 gent concentration and residence time in the microdroplet environment, affording single or double N-a

102 e kinetics of aqueous chemistry occurring in microdroplet environments require experimental technique

103 trations and other chemical manipulations in microdroplets even if they need to be kept alkaline.

104 Aqueous aerosols and microdroplets exhibit unique chemical kinetics relative

105 leagues were replicated in the corresponding microdroplet experiments.

106 ) gas-mixture was passed through a suspended microdroplet flow, where the residence time in the dynam

107 nique combines encapsulation of cells in gel microdroplets for massively parallel microbial cultivati

108 faces drying under moderate humidity, stable microdroplets form around bacterial aggregates due to ca

109 Microdroplet formation around aggregates is likely key t

110 Microdroplet formation plays a role in a variety effects

111 ected hydroxyl free radicals concurrent with microdroplet formation.

112 H(2)O(2) is spontaneously produced in water microdroplets formed by dropwise condensation of water v

113 t the production of H(2)O(2) occurs in water microdroplets formed by not only atomizing bulk water bu

114 ume solutions sets up an apparent conundrum: Microdroplets formed by spray ionization can be used to

115 lar interfaces, including those generated at microdroplets formed in dilute hexafluoro-2-propanol (HF

116 ate (dNTP) release, capture and detection in microdroplets from single DNA molecules.

117 This property is invoked to adsorb crude oil microdroplets from water using polyester polyurethane (P

118 A plasma-microdroplet fusion platform is utilized for introductio

119 Microdroplets generated in microfluidic channels hold gr

120 Also, two commonly used carrier fluids for microdroplet generation (FC-70 Fluorinert oil and silico

121 ingle microdroplets is afforded by on-demand microdroplet generation coupled to a commercial ion-trap

122 dance for complex mixtures, and here, we use microdroplet generation microfluidics to supply picolite

123 icle (NP) introduction using nebulization or microdroplet generation systems.

124 devices, allowing spatiotemporal control of microdroplet generation without additional integration o

125 pectrometer (ICPTOFMS) in combination with a microdroplet generator (MDG) for simultaneous mass quant

126 Individual droplets generated from a microdroplet generator (MDG) were merged into an aerosol

127 termination of ENPs employing a monodisperse microdroplet generator (MDG) with transport efficiencies

128 Our microdroplet generator can be effectively applied to a d

129 We developed a drop-on-demand microdroplet generator for the discrete dispensing of bi

130 nsisting of a biomolecule concentrator and a microdroplet generator, which enhances the limited sensi

131 ing evidence that the air-water interface or microdroplet geometry has no bearing on the spontaneous

132 on of single-captured bacterial cells in gel microdroplets (GMDs) to improve full genomic sequence re

133 and the growth processes of condensate water microdroplets govern H(2)O(2) generation.

134 asic electrode system compared to the random microdroplet/graphite system.

135 hrough Raman excitation in microdroplets-but microdroplets have not been used in practical applicatio

136 The mixing dynamics of unconfined (airborne) microdroplets have yet to be studied in detail, which is

137 tion phase acceleration, as is well known in microdroplets; ii) solid/solution phase, where such acce

138 Voltammetry of microdroplets immobilized on paraffin impregnated graphi

139 BQT)-which can be used to study reactions in microdroplets in a controlled environment.

140 ime through changing the shape of the liquid microdroplets in a fast, repeatable, and controlled mann

141 reading of photon-upconversion spectra from microdroplets in a microfluidic chip with frequency up t

142 we demonstrate electrotunable liquid sulfur microdroplets in an electrochemical cell.

143 on effect does not occur for certain organic microdroplets in aqueous solutions.

144 l evolution of mechanical stresses using oil microdroplets in developing zebrafish tissues.

145 pe (reaction product) is the basis for using microdroplets in directed evolution studies, and the app

146 ains, demonstrating the practical utility of microdroplets in drug development.

147 The severity of silicone oil microdroplets in eyes using BD 1.0-mL polycarbonate syri

148 Water-in-oil microdroplets in microfluidics are well-defined individu

149 and nanoparticles, within individual aqueous microdroplets in oil.

150 nalyte concentrations from within individual microdroplets in real time using SERRS spectroscopy.

151 enabled an 83% retention of the aerosolized microdroplets in the confined volume of our device.

152 ions of a device for generating monodisperse microdroplets in two distinct size regimes and in a high

153 , and sinter eutectic gallium indium (EGaIn) microdroplets in uncured poly(dimethylsiloxane) (PDMS) t

154 e methods to fabricate QD-stabilized toluene microdroplets in water as whispering gallery mode micros

155 dissolved in micron-sized aqueous droplets (microdroplets) in oil were excited, and the fluorescence

156 cular rotation is restricted at and near the microdroplet interface.

157 Microdroplets interfaced by lipid monolayers were employ

158 By spraying pure water microdroplets into a mass spectrometer, we detected OH.

159 By incorporating liquid metal (LM) microdroplets into a soft elastomer, we achieve a approx

160 e platform for introducing dynamic nano- and microdroplets into cells and organisms.

161 tact electrification between oil and a water microdroplet is demonstrated to be the origin of electro

162 any experiments, the precise volume of these microdroplets is a critical parameter which can be influ

163 water oxidation to form H(2)O(2) from water microdroplets is a general phenomenon.

164 nt of laser-induced photochemistry in single microdroplets is afforded by on-demand microdroplet gene

165 of I(-) by O3 at the air-water interface of microdroplets is evidenced by the appearance of hypoiodo

166 The average speed of the microdroplets is measured using microparticle image velo

167 A method to monitor the level of oxygen in microdroplets is presented.

168 The spontaneous formation of coacervate microdroplet-laden photo-crosslinked hydrogels derived f

169 Vitamin B2-doped microdroplet lasers are generated and trapped on a super

170 rate a polydisperse source of highly charged microdroplets, leading to multiple confounding factors p

171 Confined volume systems, such as microdroplets, Leidenfrost droplets, or thin films, can

172 Cassie-Baxter state to the Wenzel state for microdroplets less than 0.37 mm in diameter, without emp

173 ed to be dramatically accelerated in aqueous microdroplets, making them a promising platform for envi

174 It is demonstrated that single microdroplet mass spectra are recordable, one at a time,

175 Among them, membranized coacervate microdroplets (MCM) uniquely combine a molecularly crowd

176 Most reported reactions in microdroplets mirror the products found in bulk reaction

177 Microdroplet NMR is a droplet microfluidic NMR loading m

178 microscale analysis, nanoSplitter LC-MS and microdroplet NMR, for the identification of unknown comp

179 c field formed at the water-air interface of microdroplets, no catalysts or external electrical bias,

180 ilk at the sub-ppb level by simply putting a microdroplet of adulterated milk at the substrate and el

181 exible patch-sensor, which simply requires a microdroplet of aqueous starch-FeSO(4) solution to detec

182 n binding site conceptually represented as a microdroplet of ligands confined to a small volume is ex

183 se of a reactant encapsulated in a composite microdroplet of liquid perfluorohexane.

184 Merging microdroplets of different reactants is one such approac

185 Crystallization of microdroplets of molten alloys could, in principle, pres

186 ger a phase transition and the nucleation of microdroplets of one of the components of the mixture.

187 ringes, and it is difficult to differentiate microdroplets of silicone oil from particles formed by a

188 ments suggest the possibility of emission of microdroplets of solution due to the intense fields at t

189 highest reported efflorescence RH values for microdroplets of these salts.

190 Gel microdroplets offer a powerful and high-throughput techn

191 Microdroplets offer unique compartments for accommodatin

192 By imaging microdroplets on the CMOS imager surface we eliminated t

193 lowed by the repeated condensation of liquid microdroplets on the fragmented tissue, allows for maxim

194 ed the dual modality contrast effects of the microdroplets on US flow determination and PA imaging.

195 y precisely positioning a 1,2-dichloroethane microdroplet onto the ultramicroelectrode with a microin

196 0.4 ms and spray the mixture in the form of microdroplets onto an electron microscopy grid, yielding

197 We sequenced six samples enriched by microdroplet or traditional singleplex PCR using primers

198 Thus, microdroplet PCR reactions require additional polymerase

199 We scaled the microdroplet PCR to 3,976 amplicons totaling 1.49 Mb of

200 ch combining bisulfite treatment followed by microdroplet PCR with next-generation sequencing to assa

201 we describe an enrichment approach based on microdroplet PCR, which enables 1.5 million amplificatio

202 approach to enrich the target gene panel by microdroplet PCR.

203 hy genes in 12 MKS pedigrees using RainDance microdroplet-PCR enrichment and IlluminaGAIIx next-gener

204 ted intramolecular rotations at and near the microdroplet periphery are consistent with the reduced e

205 sorting of cyanobacteria and microalgae in a microdroplet platform.

206 pite the high stability of bulk water, water microdroplets possess strikingly different properties, s

207 brane at the surface of preformed coacervate microdroplets prepared from cationic peptides/polyelectr

208 Microdroplets present several unique characteristics of

209 tituted quinolines were conducted in charged microdroplets produced by an electrospray process at amb

210 similar to reaction acceleration in charged microdroplets produced by electrospray ionization.

211 Coacervate microdroplets produced by liquid-liquid phase separation

212 en pumping to accurately control the size of microdroplets produced in a microfluidic device.

213 s is the beginning of phase II, in which oil microdroplets quickly nucleate in the whole drop, leadin

214 ing tool for ambient reaction monitoring via microdroplet reaction acceleration.

215 We extended the scope of the microdroplet reaction and obtained a series of new funct

216 pared to those in the corresponding bulk and microdroplet reactions and it is concluded that the rate

217 This work clearly indicates that microdroplet reactions can show reactivity quite differe

218 accommodate the low flow rates preferred for microdroplet reactions.

219 forcement learning integrated with a modular microdroplet reactor capable of performing reaction step

220 Complementary to cavitational chemistry, the microdroplet reactors created by USP facilitate the form

221 ature on SERRS-based detection of individual microdroplets remains lacking.

222 Stability of pH in the microdroplets required for different determinations and

223 In this way, Zn(II) can also be titrated in microdroplets, requiring a pH around 10.

224 The highly QD-stabilized toluene microdroplet resonators in the all-liquid phase would be

225 alysis of treponemes embedded in agarose gel microdroplets revealed that only minor portions of Msp a

226 ntal physical and chemical processes such as microdroplet role in reaction catalysis in nature as wel

227 Moreover, the microdroplets selectively sequester porphyrins, inorgani

228 The microdroplets served as carriers for PA contrast agent s

229 Each microdroplet serves as a reaction vessel that identifies

230 significant difference between silicone oil microdroplet severity between BD 1.0-mL polypropylene sy

231 method for performing two-phase reactions in microdroplets sheared by sheath gas without using a phas

232 The toluene microdroplets show size-dependently high Q-factors up to

233 ons of the H(2)O(2) production in condensate microdroplets showed that H(2)O(2) was generated from mi

234 Besides, the in vivo evaluation with microdroplets showed US flow enhancement for more than 6

235 m mass spectrometry (MS(2)) of the resulting microdroplets shows the direct formation of phenol via d

236 performance depend on the properties of the microdroplet spray, sample, and surface.

237 both oxygen and LLL12 in stimuli responsive microdroplets (SRMs) by a gas-driven coaxial flow focusi

238 to generate two well-controlled monodisperse microdroplet streams and collide (and thus mix) the micr

239 In DESI-MSI, microdroplets strike the tissue sample, the resulting sp

240 estimated from times of coalescing ballistic microdroplets, suggest that complete mixing occurs withi

241 strates its unusual stability at the aqueous microdroplet surface, enabling its detection and transfo

242 ation of SO2(g) on the interfacial layers of microdroplet surfaces was investigated using a spray-cha

243 Each of the microdroplets suspended on the surface of fluorinated li

244 ur microscopy method, we jet and image water microdroplets suspending fluorescent nanoplastics, count

245 al, generated at the gas-liquid interface of microdroplets, synergistically triggered the interfacial

246 Our results demonstrate that microdroplet technology is well suited for processing DN

247 Many reactions show much faster kinetics in microdroplets than in the bulk phase.

248 tides spontaneously accumulate in water into microdroplets that are stable to changes in temperature

249 mical wisdom; reactions in electrified water microdroplets that do not occur in bulk water, transform

250 ulosis (Yptb) growth in microfluidics-driven microdroplets that regenerates microbial social behavior

251 ent variation of the well content results in microdroplets that represent time capsules of the compos

252 e, the ion and ligands behave as a "confined microdroplet" that is free to fluctuate and adapt to ion

253 izer plume is an efficient way of generating microdroplets the uniquely complex reaction environment

254 om the original large ESI droplets and these microdroplets then desolvate without a significant decre

255 ligases, coupled with volume restriction in microdroplets, this method allows us to simultaneously d

256 Here we report the use of aqueous microdroplets to accelerate enzymatic reactions and, in

257 uently exposing the resultant electrosprayed microdroplets to formic acid vapor, the ketone intermedi

258 stic properties, from liquid-like coacervate microdroplets to hydrogels to stiff solid materials.

259 intercept intermediates of this reaction in microdroplets to validate a mechanism proposed herein.

260 g can be achieved when using airborne merged microdroplets to, e.g., study reaction kinetics when rea

261 t relates to the time course and distance of microdroplet travel.

262 In addition, the microdroplets typically coalesce at temperatures higher

263 The N-alkylation yield is moderate in microdroplets, up to 53 %.

264 ty in atmospheric aqueous aerosols and water microdroplets used for catalysis.

265 highly accurate real-time pH measurements of microdroplets using aerosol optical tweezers (AOT) and a

266 ing micropillars from pipette-dispensed PDMS microdroplets using vacuum-chucked microspheres.

267 the self-electrification and discharging of microdroplets, vapor, and bulk phase by electron and ion

268 copolymers showed coacervate-like spherical microdroplets (varphi approximately 1-5 mum at pH approx

269 selective N-alkylation of indoles in aqueous microdroplets via a three-component Mannich-type reactio

270 ate, incubate, track, and analyze individual microdroplets via real-time, long-term imaging unleash i

271 The rapid oxidation of SO2(g) on the acidic microdroplets was estimated as 1.5 x 10(6) [S(IV)] (M s(

272 The severity of silicone oil microdroplets was significantly greater in eyes using BD

273 e standard deviation of barcode reading from microdroplets was ~1%.

274 rom a homemade setup to produce tiny (~9 um) microdroplets, we obtain 100% sequence coverage in less

275 Using spatially extended arrays of microdroplets, we study the diffusion of both AHL and IP

276 Using the dual-modality microdroplets, we were able to obtain distinct edges of

277 imaging contrast performance, hydrogel-based microdroplets were designed for both US blood flow and P

278 Silicone oil microdroplets were graded on a scale from 0 to 4+ based

279 The DNA-enriched microdroplets were manipulated by application of a magne

280 Silicone oil microdroplets were observed in 78.3% of eyes receiving b

281 ssay in which treponemes encapsulated in gel microdroplets were probed with syphilitic sera in parall

282 irochetes encapsulated in agarose beads (gel microdroplets) were incubated with antibodies to these s

283 produced in micrometer-sized water droplets (microdroplets), which are generated by atomizing bulk wa

284 ) is trafficked into the attached coacervate microdroplets, which are then released as functionally m

285 hod can instantaneously tune the size of the microdroplets, which has applications in composites, cat

286 w capability of studying electrochemistry in microdroplets, which offers an opportunity to understand

287 lso rapidly growing interest in the field of microdroplets, which promises to offer the analyst many

288 entrapment of the solutes within an aqueous microdroplet, while the water molecules from the droplet

289 e analysis of treponemes encapsulated in gel microdroplets, while opsonization assays failed to detec

290 n water, and the solution is sprayed to form microdroplets whose chemical contents are analyzed mass

291 mits the analysis of mixing phenomena within microdroplets with a temporal resolution of 1 mus.

292 c tissues, using fluorescent, cell-sized oil microdroplets with defined mechanical properties and coa

293 oplet streams and collide (and thus mix) the microdroplets with high spatial and temporal control whi

294 into designing surfactants that form robust microdroplets with improved stability and resistance to

295 oluble proteins self-organize into condensed microdroplets with nanoscale and millisecond space and t

296 lets showed that H(2)O(2) was generated from microdroplets with sizes typically less than ~10 um.

297 mical microscope (SECM) were accomplished in microdroplets with solution volumes of less than 1 nL.

298 Spherical cap-shaped polystyrene microdroplets, with nonequilibrium contact angle, are pl

299 negatively or positively charged coacervate microdroplets within the aqueous lumen of individual pro

300 on the millisecond timescale in the charged microdroplets without the addition of any external acid.