ライフサイエンスコーパス: microsecond

1 ary impulse is on the order of a few hundred microseconds).

2 by Rydberg-level interactions in less than a microsecond.

3 known to deprotonate, at most, within a few microseconds.

4 omains undergo a left handed rotation within microseconds.

5 G(N2-H)(.) to dG(N1-H)(.) within hundreds of microseconds.

6 tens of nanometers and timescales of tens of microseconds.

7 echanical coherence times on the order of 10 microseconds.

8 d to enhanced carrier lifetime up to several microseconds.

9 ination lifetime from several nanoseconds to microseconds.

10 these approaches have not yet exceeded a few microseconds.

11 s a proton transfer lasting over hundreds of microseconds.

12 c reaction zone was limited to a few hundred microseconds.

13 tes are Mo2deltadelta* with lifetimes in the microseconds.

14 nformations that exchange within hundreds of microseconds.

15 e microenvironmental parameters within a few microseconds.

16 of extensive vacancy pits within a period of microseconds.

17 nces into functioning proteins, sometimes in microseconds.

18 ry slow in CH3NH3PbI3, lasting up to tens of microseconds.

19 est that complete mixing occurs within a few microseconds.

20 resulting in a transition time of 300 to 800 microseconds.

21 tallization occurs on time scales of 3 to 50 microseconds.

22 algorithm with a processing time of tens of microseconds.

23 lation and show lifetimes of several tens of microseconds.

24 ere deadtime reached a value as low as a few microseconds (22 us for (204)Tl, 26 us for (137)Cs, 9 us

25 polarization of free holes has a lifetime of microseconds(5-9).

26 Advances in computing have enabled microsecond all-atom molecular dynamics trajectories of

27 ading to carrier lifetimes of greater than 1 microsecond and diffusion lengths of 2.5 micrometers.

28 ergy relaxation time of T1 approximately 100 microseconds and a phase-coherence time of T2 approximat

29 However, especially on the scale of microseconds and nanometers, position and orientation fl

30 quantitate parallel dynamics on hundreds of microseconds and tens of milliseconds timescales, likely

31 y observed due to its short lifetime (in the microseconds) and unique breakdown signature.

32 cs at timescales ranging from nanoseconds to microseconds, and other "jittering" motions at timescale

33 milliseconds (in rapid-scan FT-IR) to a few microseconds, as demonstrated here in the case of ammoni

34 net in which long coherence times (up to 8.4 microseconds at 5 kelvin) are obtained at unusually high

35 signature that persists for several tens of microseconds, before charge recombination with NiO holes

36 s an observable folding intermediate, but no microsecond burst phase in the folding kinetics of the s

37 nd nanoscience frequently occur on fast (sub)microsecond but not ultrafast timescales which are diffi

38 ionally high input precision in the range of microseconds, but not in mice.

39 All five WW domains fold in microseconds, but with a 10-fold difference between fast

40 an exceptionally long carrier lifetime (4.7 microseconds) comparable to that of bulk silicon, wherea

41 n approach that allows the quantification of microsecond conformational exchange in large protein com

42 ingle 600-ns electric pulse, we observed sub-microsecond, continuous membrane charging and dischargin

43 resolved PL imaging analyses highlighted the microsecond decay-kinetic behavior of the emission, conf

44 simulation times ranging from nanoseconds to microseconds depending on system size.

45 obtain self-starting Q-switched pulses with microsecond duration and kilohertz repetition rates at 1

46 A new approach brought on by the advent of microsecond dwell times in single particle ICP-MS allows

47 sensitivity sector field ICP-MS (ICP-SF-MS), microsecond dwell times, and dry aerosol sample introduc

48 method for the observation of picosecond to microsecond dynamics of proteins when transiently intera

49 f the apo-form, enhancing the millisecond to microsecond dynamics of the holo-form at sites critical

50 Here we probe how the crystal packing alters microsecond dynamics, using solid-state NMR measurements

51 fferent constructs, all are within range for microsecond electron transfer.

52 In its free form, the protein undergoes a microsecond exchange between two states, one of which is

53 , luminescence quantum yields up to 0.20 and microsecond excited state lifetimes are achieved in solu

54 nstant pH molecular dynamics (MD) method and microsecond fixed-charge all-atom MD simulations.

55 The recorded microsecond flash photolysis data were subjected to deta

56 lex dynamics in many degrees of freedom, yet microsecond folding experiments provide only low-resolut

57 We find microsecond folding times, consistent with temperature j

58 his ordering is robust and persists into the microsecond folding timescale.

59 and a coherence time of [Formula: see text] microseconds for bandgap-shielded cavities.

60 es over their intrinsic physical timescales (microseconds for microbubble dynamics and seconds to min

61 ndreds of picoseconds, but slows down to sub-microseconds in a sample with 33% PC61BM.

62 a very long spin relaxation lifetime of many microseconds in the Mott insulating state, orders of mag

63 Although slow relaxation beyond microseconds is observed in different perturbative simul

64 ctional selectivity, we carried out unbiased microsecond-length MD simulations of the human serotonin

65 of positional mutual information in multiple microsecond-length molecular dynamics (MD) simulations t

66 ctive to active state by performing unbiased microsecond-length molecular dynamics (MD) simulations,

67 distance change with temporal resolution at microsecond level and structural resolution at Angstrom

68 Employing microsecond-level molecular dynamics (MD) simulations, w

69 phosphorescence with large Stokes shift and microsecond lifetime.

70 Both theory and experiment exhibit microsecond lifetimes for this state.

71 measurements reveal long-lived carriers with microsecond lifetimes in the alloyed material, which is

72 ieve photoluminescence efficiencies >99% and microsecond lifetimes, which lead to an efficient blue-e

73 r triplet excited states, according to their microsecond lifetimes, with quantum yields of up to 58%.

74 LFP studies indicate transient species with microsecond lifetimes.

75 Combining with a number of microsecond long MD simulations, we also found that the

76 cally, we have performed several independent microsecond long molecular simulations of TAR based on o

77 Intriguingly, during the sub-microsecond long simulation, we observed Arg269 undergoi

78 enhancement is enabled by the induction of a microsecond long-lived charge separated state, consistin

79 Microsecond-long all-atom molecular dynamics simulations

80 Here, we simulate CypA using multiple-microsecond-long atomistic molecular dynamics in explici

81 Our microsecond-long atomistic simulations elucidate key str

82 We performed three independent microsecond-long MD simulations to evaluate the structur

83 Comparison of microsecond-long molecular dynamics simulations of Kv 1.

84 Here, we use all-atom, microsecond-long molecular dynamics to simulate the stru

85 On the basis of microsecond-long parallel-tempering metadynamics and tem

86 Here we show that in a state-of-the-art, microsecond-long simulation of the same DNA sequence, th

87 Using microsecond-long simulations, we examined the open and c

88 We have analyzed microsecond-long trajectories of E1.H(+)771, a protonate

89 Examination of these interactions using microsecond-long unrestrained simulations shows that ure

90 arly stages of the synthesis of MIL-101(Cr). Microsecond-long well-tempered metadynamics simulations

91 Microsecond-long, unbiased MD simulations illustrate tha

92 ral angles were computed using the output of microseconds-long atomistic simulations.

93 o-EM) open-state channel structure, multiple microseconds-long molecular-dynamics (MD) trajectories w

94 n in torsion angle movements calculated from microseconds-long molecular-dynamics simulations, we elu

95 reducing pulse duration from milliseconds to microseconds markedly decreases the minimal pulse energy

96 The allosteric mechanism was probed by microsecond MD simulations in explicit water, complement

97 Microsecond MD simulations indicated that the BH3 domain

98 using solid-state NMR measurements and multi-microsecond MD simulations of different crystal forms of

99 Further insight was obtained from microsecond MD simulations, which revealed a large struc

100 ectrophoresis, site-directed mutagenesis and microsecond MD simulations.

101 e fingers domain of T7 RNAP according to the microsecond MD simulations.

102 Two accelerated, half microsecond, MD simulations of the system having protona

103 we present a method to characterize protein microsecond-millisecond dynamics based on the analysis o

104 The free form of YmoA shows collective microsecond-millisecond dynamics that can by measured by

105 els that are computationally testable in the microsecond-millisecond regime.

106 tate to an intermediate state, by the use of microsecond mixing experiments.

107 mulation-2 (ST2) as an example, we performed microsecond molecular dynamics (MD) simulations to study

108 We present the results of microsecond molecular dynamics simulations carried out b

109 -grained (CG) simulation method that enables microsecond molecular dynamics simulations of full-lengt

110 Microsecond molecular dynamics simulations of harzianin

111 med extensively long unconstrained, all-atom microsecond molecular dynamics simulations of nucleosome

112 f the conserved Trp207 with solvent in multi-microsecond molecular dynamics simulations of the Dio3 t

113 Microsecond molecular dynamics simulations permitted a c

114 We employ here microsecond molecular dynamics simulations to probe the

115 Here, we have performed microsecond molecular dynamics simulations to probe the

116 PAM-induced allosteric mechanism revealed by microsecond molecular dynamics simulations.

117 dary structure stability utilizing extensive microsecond molecular dynamics simulations.

118 s the analogous ET systems, are studied with microsecond molecular dynamics, and the ET and PCET rate

119 From microsecond molecular-dynamics simulations, we are able

120 ov modelling analysis of an aggregate of 275 microseconds molecular dynamics simulations, we reveal t

121 nced intermediate time scale (millisecond to microsecond) motions in the mutant.

122 tions uncovered site-dependent nanosecond-to-microsecond movement of secondary and tertiary structure

123 Protein dynamics on the microsecond (mus) time scale were investigated by temper

124 ion bubble, which forms and collapses within microseconds of ablation.

125 These simulations yielded over 250 microseconds of accumulated data, which correspond to ap

126 In this work, we carried out tens of microseconds of all-atom MD simulations to investigate t

127 After 135 microseconds of cooling, we observed a reduction in ion

128 ecular dynamics simulations spanning several microseconds of dsDNA packing inside nanometer-sized vir

129 al backbone NH groups within the initial 140 microseconds of folding of horse cytochrome c.

130 of CLC-2 "fast" (pore) gating, based on 600 microseconds of molecular dynamics (MD) simulation.

131 To verify this hypothesis, microseconds of molecular dynamics simulations were comp

132 The results of >16 microseconds of simulation predict that polymyxin B1 is

133 nds, while Cer and cholesterol take around a microsecond or longer to translocate.

134 duce ion pulse widths typically around a few microseconds or less for ion mobility spectrometry (IMS)

135 r and a slower kinetic phase, and the "slow" microsecond phase is activated.

136 We present such a comparison of microsecond pressure and temperature jump refolding kine

137 Compared to microsecond pulses, ~800 ns pulses can be used to increa

138 by more than a factor of 2 in comparison to microsecond pulses.

139 Microsecond radiolytic labeling identified rearrangement

140 lifetimes within the relevant nanosecond to microsecond range.

141 iques of computational chemistry [e.g., long-microsecond-range, all-atom molecular dynamics (MD) simu

142 tial for such studies over the nanosecond to microsecond real time scales.

143 to non-native helical structure frustrating microsecond refolding.

144 more, we observe a transient response in the microsecond regime associated with slow lattice cooling,

145 ce times from few tens of nanoseconds to the microsecond regime between 2 and 3 T magnetic field and

146 d H/D exchange labeling experiments into the microsecond regime by adopting a microfluidics approach.

147 revealed rotational correlation times in the microsecond regime, suggesting that rotational fluidity

148 time of the nanofiber from the nanosecond to microsecond regime.

149 re we show a fast algorithm suitable for the microsecond region with precision closely approaching th

150 ell below the dephasing times of roughly 100 microseconds reported for superconducting qubits(15) and

151 Using force spectroscopy optimized for 1-microsecond resolution, we reexamined the unfolding of i

152 Recent microsecond-resolution experiments and long duration (to

153 Microsecond resolved spectra can be obtained with high s

154 nt time correlation function analysis to the microsecond-resolved smFRET data obtained to determine a

155 Microseconds-resolved laser temperature-jump perturbatio

156 ntrolled on the timescale of nanoseconds and microseconds respectively.

157 ved brightness and voltage sensitivity, have microsecond response times and produce no photocurrent.

158 re generally thought to be slow devices with microsecond response times, thereby limiting their full

159 ts of cMyBP-C and its phosphorylation on the microsecond rotational dynamics of actin filaments, we a

160 ments with polarized light, in which tens-of-microseconds rotational motions of internally labeled iC

161 MD simulations were performed at a microsecond scale and combined with Monte Carlo sampling

162 measurement of luminescence lifetimes on the microsecond scale based on variable excitation time dete

163 In recent microsecond scale molecular dynamics simulations of a co

164 ventional molecular dynamics (MD) beyond the microsecond scale.

165 Microsecond-scale atomistic molecular dynamics simulatio

166 -photon fluorescence microscope and achieved microsecond-scale axial scanning, thus enabling volumetr

167 ed on a dual-resolution approach, using both microsecond-scale explicit-solvent all-atom and coarse-g

168 spension have been observed to emit delayed, microsecond-scale fluorescence arising from upconverted

169 From microsecond-scale molecular dynamics simulations and cog

170 of partial agonism, we performed comparative microsecond-scale molecular dynamics simulations startin

171 e of T. thermophilus complex I, we have used microsecond-scale molecular dynamics simulations to stud

172 in protein kinases, we carried out multiple microsecond-scale molecular-dynamics simulations of prot

173 modern mass spectrometry (MS) operating with microsecond scan speeds.

174 We performed microsecond sequential XPCS experiments probing equilibr

175 tructure have now been identified in a multi-microsecond simulation of the same reverse micelle syste

176 ized membranes; and demonstrate the need for microsecond simulations for even simple permeants like w

177 We perform multi-microsecond simulations in 1-palmitoyl-2-oleoyl-sn-glyce

178 ion models is analyzed in detail using multi-microsecond simulations.

179 slab-bilayer (sandwich) structures and multi-microsecond simulations.

180 sible regime located between millisecond and microsecond single pulse illumination.

181 We here report microsecond single-molecule FRET (smFRET) measurements o

182 torage for up to 20 ms, and are used for few-microsecond single-qubit and two-qubit control gates wit

183 ded DNA, the SaS nanopore enabled sensing at microsecond speed with a signal-to-noise ratio of 21, co

184 By using microsecond standard and accelerated molecular dynamics

185 neous metal and proton pathways during fast (microsecond) structural transitions remains unknown.

186 In addition, free MD simulations up to one microsecond suggest that the calculated profiles are hig

187 We show microsecond-sustained lasing, achieved by placing ultra-

188 ile observing the bead's thermal motion with microsecond temporal and nanometer spatial resolution us

189 cultures with hundreds of microelectrodes at microsecond temporal resolution.

190 or longer, biologically relevant timescales (microseconds), the need for improved computational metho

191 pin coherence persists for longer than a few microseconds, the output of the sensor contains a sharp

192 with a robust 'plateau' that extends over a microsecond; the rate constants vary by two orders of ma

193 eparated states with lifetimes as long as 61 microseconds, thereby mimicking the functions of the nat

194 efficiently reject laser background through microsecond time gating.

195 ved Forster resonance energy transfer in the microsecond time range of refolding.

196 lete temporal resolution over the picosecond-microsecond time range, to propose a new mechanism for t

197 populate an off-pathway kinetic trap in the microsecond time range.

198 Microfluidic mixing with microsecond time resolution and Forster resonance energy

199 perpendicular to the lipid surface on a low microsecond time scale ( approximately 2 mus), while sim

200 ow-trapped electrons that exist at about the microsecond time scale after photoexcitation are key to

201 3 is kinetically reactive and reacts in the microsecond time scale following a first-order kinetic l

202 clusters in our F8BT nanoparticles from the microsecond time scale onward and show that the predomin

203 mic features of substrates on the nanosecond-microsecond time scale that correlate with enzymatic rat

204 asize the need to examine motions on the low microsecond time scale when probing these types of inter

205 apable of measuring pA-range currents on the microsecond time scale with a very low noise and stable

206 linking substrate dynamics on the nanosecond-microsecond time scale with large collective substrate m

207 ormation of polar hydrated layers at the sub-microsecond time scale, however with a thickness of only

208 endo and vice versa is on the nanosecond and microsecond time scale, respectively.

209 s efficiently in all systems on the nano- to microsecond time scale, through three distinct routes: r

210 ew nanoseconds, followed by its decay in the microsecond time scale.

211 r from oxidized dye to IrO2 occurring on the microsecond time scale.

212 rly 500 mus of refolding was revealed on the microsecond time scale.

213 rizing the internal dynamics of TAR over the microsecond time scale.

214 -ordered character form and disappear on the microsecond time scale.

215 d hole mobilities remain very high up to the microsecond time scale.

216 hairpin WW domain system, which folds on the microsecond time scale.

217 crofluidic mixing to observe kinetics on the microsecond time scale.

218 nable lateral proton transfer reactions on a microsecond time scale.

219 easurements on the femto-, pico-, nano-, and microsecond time scales and are examined by multiwavelen

220 measurements on the femto, pico-, nano-, and microsecond time scales and by multiwavelength and targe

221 rge recombination on both the nanosecond and microsecond time scales in a donor-acceptor system compr

222 d catalysis are much slower (millisecond and microsecond time scales).

223 etails of dynamic cantilever response at sub-microsecond time scales, higher-order eigenmodes and har

224 ules to larger pools and from femtosecond to microsecond time scales.

225 igand recognition loop occurring on multiple microsecond time scales.

226 Here, we investigate the mechanism at the microsecond time- and nanometer space- scale using MD si

227 even further advances, such as high-quality microsecond time-resolved XFMS studies.

228 on methods provide a holistic way to observe microsecond time-scale protein backbone motion both in s

229 triplet excited-state (T1) lifetimes on the microseconds time scale are simultaneously realized.

230 e with an 3-5 degrees amplitude on a tens-of-microseconds time scale in one of the crystals, but not

231 S0 conversion dynamics that short-circuit a microseconds time scale triplet lifetime.

232 rved spectroscopically on the nanoseconds to microseconds time scale.

233 in CB2.Gi complex formation, we carried out microsecond-time scale molecular dynamics simulations of

234 The microsecond-time scale recombination is probably gated b

235 Here, we performed microsecond timescale all-atom molecular dynamics (MD) s

236 BSC0OL15) show predictive power in the multi-microsecond timescale and can be safely used to reproduc

237 te with reorganization of the bilayer on the microsecond timescale and persist throughout a total of

238 s substantial dynamics on the millisecond-to-microsecond timescale but autoinhibited and DNA-bound ER

239 erize the rearrangements in nucleosomes on a microsecond timescale including the coupling between the

240 thermodynamic free energy cycle approach and microsecond timescale molecular dynamics simulations.

241 Computers now allow microsecond timescale molecular-dynamics simulations, wh

242 Microsecond timescale trajectories reveal the intrinsic

243 n an explicit lipid-water environment over a microsecond timescale unraveled the role of kindlin as a

244 f protein structures and interactions on the microsecond timescale, enabling investigations of fast p

245 eptide unfolds and refolds repeatedly on the microsecond timescale, indicating that the alpha-helical

246 the central binding site to the lumen has a microsecond timescale, revealing a novel passive cytopla

247 g tryptophan in the open BM2 reorient on the microsecond timescale, similar to AM2, indicating that s

248 at the fully assembled pump is stable in the microsecond timescale.

249 ion diffusion in Gd2Ti2O7 pyrochlore, on the microsecond timescale.

250 enough to drive concerted motions on the sub-microsecond timescale.

251 ns such as lambda-repressor that fold on the microsecond timescale.

252 ional intramolecular protein dynamics on the microsecond timescale.

253 Unbiased microsecond-timescale all-atom molecular dynamics simula

254 c spines, synaptic transmission, subcellular microsecond-timescale details of AP propagation, and sim

255 This mechanistic insight, enabled by microsecond-timescale MD simulations, will allow a caref

256 Interactions with metal ions attenuate microsecond-timescale motions of the loop regions, indic

257 Microsecond-timescale simulations have calculated that t

258 ansient absorption measurements performed on microsecond timescales reveal that, unlike the native N

259 d for studying irreversible reactions at sub-microsecond timescales using high-brightness X-ray facil

260 We find nonlinear heating on microsecond timescales with dynamics beyond hot Brownian

261 unprecedented mobility on the nanosecond to microsecond timescales, and the experimental NMR dipolar

262 observed in hERG1-WT simulations occurred at microsecond timescales, influenced by the spontaneous de

263 erformance molecular dynamics simulations at microsecond timescales.

264 sidue-specific probes of motions on nano- to microsecond timescales.

265 representations of acoustic signals resolves microsecond timing of sounds processed by the two ears.

266 QM PDZ, but not other mutants, had extensive microsecond to millisecond motions distributed throughou

267 al validation demonstrate detectable "slow" (microsecond to millisecond) conformational exchange rate

268 plicity of states in the ensemble and rapid (microsecond to millisecond) exchange between them.

269 cant increase in the scanning speed from the microsecond to nanosecond regime, which represents a maj

270 oatings to expel water and collapse within a microsecond to the nanoscale, millions of times faster t

271 which probes displacements over hundreds of microseconds to milliseconds, to reveal the conformation

272 ides a large dynamic range of lifetimes from microseconds to milliseconds, which allows creating larg

273 ifferent conformational states range between microseconds to milliseconds, which clearly implicate al

274 , the same information can be extracted from microseconds to seconds long time traces; however, an ap

275 ics of materials on time scales ranging from microseconds to thousands of seconds and length scales r

276 Protein-protein complexes, lasting from microseconds to years, often involve induced-fit, challe

277 on-based gating (in the order of hundreds of microseconds) to improve the spatiotemporal resolution b

278 odeling that provide unprecedented access to microsecond- to millisecond-timescale fluctuations of a

279 edict that unspecific interactions slow down microsecond- to millisecond-timescale protein dynamics d

280 cal responses in U1A, they produce extensive microsecond-to-millisecond global motions throughout SNF

281 Recently, a study of the late, microsecond-to-millisecond kinetics of photointermediate

282 s in conformational exchange dynamics in the microsecond-to-millisecond time regime between the diffe

283 Our results demonstrate that a microsecond-to-millisecond time scale conformational tra

284 The intrinsic microsecond-to-millisecond timescale dynamics of the dsR

285 s timescales, base-pair/tertiary dynamics at microsecond-to-millisecond timescales, stacking dynamics

286 (picosecond to nanosecond) and intermediate (microsecond-to-millisecond) dynamics of U1A and SNF RRM1

287 for studies of biomolecular dynamics on the microsecond-to-second timescale and focus on application

288 We characterized Myr insertion events from microsecond trajectories and examined the membrane respo

289 In this work we exploit femtosecond to microsecond transient IR spectroscopy to record, in D2 O

290 ed nucleotide that releases guanosine within microseconds upon photosolvolysis with blue light.

291 r entanglement gates operated within tens of microseconds using the vibrational motion of few-ion cry

292 fluorescence with lifetimes on the order of microseconds was observed.

293 e and absorption spectroscopy from femto- to microseconds, we provide the first experimental evidence

294 r time scale structural dynamics (nanosecond-microsecond) were the source and therefore impart the co

295 w on time scales between 20 nanoseconds to 3 microseconds, whereas crystallization occurs on time sca

296 ntermediates with half-lives on the order of microseconds, which is 4-5 orders of magnitude faster th

297 er a wide time range, from subpicoseconds to microseconds with a combination of ultrafast optical ele

298 agnitude in time, from one nanosecond to ten microseconds, with a single adjustable parameter.

299 ordetella bronchiseptica Irradiating ZIPB by microsecond X-ray pulses activated water molecules to fo

300 Previously, we successfully developed microsecond XFMS using microfluidic capillary flow and a