ライフサイエンスコーパス: microstimulation

1 recordings of neuronal activity and cortical microstimulation.

2 somatosensory cortex (S1) via intracortical microstimulation.

3 rtex in behaving monkeys using intracortical microstimulation.

4 nd in turn impaired thresholds for detecting microstimulation.

5 ntal eye field (FEF) following intracortical microstimulation.

6 nsory areas of their brains using electrical microstimulation.

7 on affects saccadic eye movements during FEF microstimulation.

8 ned how discriminability was affected by FEF microstimulation.

9 rally relevant," long-duration intracortical microstimulation.

10 Movement kinematics were not altered by microstimulation.

11 hese primates using long-train intracortical microstimulation.

12 in motor cortex as assessed by intracortical microstimulation.

13 to optical imaging and patterned electrical microstimulation.

14 ght cells to weak single pulse intracortical microstimulation (20 microA) through a nearby electrode

15 nalysis of EMG activity evoked by repetitive microstimulation (200 Hz, 500 ms) of primary motor corte

16 response to touch following spike-triggered microstimulation, along with decreased neural variabilit

17 NRA neurochemical microstimulation also generated vocalizations (guttural

18 At such OT sites, AGF microstimulation also sharpened auditory receptive field

19 (Callithrix jacchus) by using intracortical microstimulation and an architectonic analysis.

20 ssed these questions using singing-triggered microstimulation and chronic recording methods in the si

21 s obtained from causality-based experiments (microstimulation and inactivation).

22 tion pathways, particularly as elucidated by microstimulation and lesion studies; (iii) top-down modu

23 Other approaches, such as microstimulation and lesions, have documented the import

24 Electrical microstimulation and more recently optogenetics are wide

25 ation of neural circuitry through electrical microstimulation and optogenetic techniques is important

26 ation of neural circuitry through electrical microstimulation and optogenetic techniques is important

27 causal link with heading perception, we used microstimulation and reversible inactivation techniques

28 We investigated RN motor map maturation with microstimulation and RST cervical enlargement projection

29 Experiments using microstimulation and single-neuron electrophysiology sug

30 Together, our microstimulation and single-neuron results suggest that

31 Microstimulation and tracer injection sites were verifie

32 Microstimulation and trans-synaptic tracing identified t

33 criminability was apparent immediately after microstimulation and was reliable within 40 ms of micros

34 ion of PPC based on intracortical long-train microstimulation, and they identify parts of cortical ne

35 Here we show that electrical microstimulation applied to gaze control circuitry in th

36 This suggests multichannel microstimulation as a viable means of sensorizing neural

37 from pulvinar neurons that we identified by microstimulation as receiving input from SC and/or proje

38 Electrical microstimulation at caudate sites during motion viewing

39 ral hours, here we used transient electrical microstimulation at different periods while monkeys perf

40 Microstimulation at PW4 evoked contralateral wrist, elbo

41 can be signaled through phasic intracortical microstimulation at the onset and offset of object conta

42 In contrast, microstimulation at the same recording sites does bias d

43 ctural dynamics, two important approaches to microstimulation at this scale, are briefly reviewed.

44 By combining such optical recordings with microstimulation at two well-separated sites of M1, we d

45 this question, we perturbed SMA activity via microstimulation at variable times before movement onset

46 To test this, we implemented a microstimulation-based neuroprosthesis that rats used to

47 the spinal cord, we synchronized intraspinal microstimulation below the injury with the arrival of fu

48 In one monkey, microstimulation biased speed judgments toward the prefe

49 on by GCaMP3 were confirmed by intracortical microstimulation but were more difficult to detect using

50 that the interaction of expected reward with microstimulation can be explained if expected reward mod

51 We argue that caudate microstimulation can differentially increase stimulus va

52 Electrical microstimulation can establish causal links between the

53 ld traversed by the target indicate that dSC microstimulation can interfere with signals encoding the

54 onstrate that low-amplitude, brief trains of microstimulation can lead to persistent changes in neuro

55 However, how microstimulation changes the neural substrate is still n

56 rd trials that were accompanied by phasic SN microstimulation compared with reward trials without sti

57 n its differential response to intracortical microstimulation compared with the caudal whisker area (

58 At the same time, AGF microstimulation decreases the responsiveness of OT neur

59 Although microstimulation delivered through multiple implanted el

60 In addition, microstimulation delivered to forepaw VPL antidromically

61 uided by spatiotemporal patterns of cortical microstimulation delivered to primary somatosensory cort

62 Even on trials in which microstimulation did not induce a preferred direction ch

63 Microstimulation did not reduce overall confidence in th

64 d unit-pair mutual information, while random microstimulation did not.

65 n et al., 2018) that was affected by caudate microstimulation (Doi et al., 2020).

66 Microstimulation drove the eyes accurately to the site o

67 neurons, using microelectrode recordings and microstimulation during awake surgery for Parkinson's di

68 CIP-microstimulation during fMRI further suggests that CIP p

69 ining reversible inactivation and electrical microstimulation during fMRI provides a detailed view of

70 ure selectivity and then employed electrical microstimulation during functional magnetic resonance im

71 lso found causal evidence that intracortical microstimulation during motor preparation was sufficient

72 These microstimulation effects included coordinated changes in

73 Here we used functional MRI, microstimulation, electrophysiology, and deep networks t

74 FEF microstimulation enhanced the PLR to probes presented wi

75 Microstimulation even perturbed the percept of certain o

76 se the normalization model and recording and microstimulation experiments to show that the attention

77 conducted electrophysiological recording and microstimulation experiments to test the hypothesis that

78 In microstimulation experiments, we activated clusters of M

79 netics as a viable alternative to electrical microstimulation for the precise dissection of the corti

80 While microstimulation had no effect on the percept of many no

81 s could be explained by a simple model where microstimulation has a stereotyped impact on the probabi

82 For over a century, electrical microstimulation has been the most direct method for cau

83 High-frequency repetitive microstimulation has been widely used as a method of inv

84 High-frequency, long-duration intracortical microstimulation (HFLD-ICMS) is increasingly being used

85 high-frequency, long-duration intracortical microstimulation (HFLD-ICMS) to primary motor cortex (M1

86 This study used intracortical microstimulation (ICMS) and electromyographic (EMG) reco

87 limb movement responses during intracortical microstimulation (ICMS) and movements of the forelimb on

88 Intracortical microstimulation (ICMS) and recording of evoked jaw and

89 essed this knowledge gap using intracortical microstimulation (ICMS) concurrently with intrinsic sign

90 into proportional subthreshold intracortical microstimulation (ICMS) during hours of unrestrained vol

91 nsory feedback was provided by intracortical microstimulation (ICMS) encoding egocentric bearing to t

92 1 forelimb representation with intracortical microstimulation (ICMS) in male squirrel monkeys.

93 nt with this general function, intracortical microstimulation (ICMS) in the PM of sufficient frequenc

94 Intracortical microstimulation (ICMS) is a powerful tool to investigat

95 icial tactile feedback through intracortical microstimulation (ICMS) of the primary somatosensory cor

96 Intracortical microstimulation (ICMS) of the primary somatosensory cor

97 Intracortical microstimulation (ICMS) of the somatosensory cortex evok

98 Intracortical microstimulation (ICMS) studies have provided two contra

99 We used intracortical microstimulation (ICMS) to determine the representation

100 ws (Tupaia belangeri) by using intracortical microstimulation (ICMS), corticospinal tracing, and deta

101 lysis combining layer-specific intracortical microstimulation (ICMS), CSD analysis, and pharmacologic

102 derived using high-resolution intracortical microstimulation (ICMS).

103 areas of a "decoder" rat using intracortical microstimulation (ICMS).

104 tactile sensation produced by intracortical microstimulation (ICMS).

105 Microstimulation+imaging opened a unique possibility for

106 We find that microstimulation improves performance in a spatially sel

107 e, we addressed this gap using intracortical microstimulation in a broad range of frontal cortical ar

108 otor and parietal cortex using intracortical microstimulation in anesthetized capuchin monkeys.

109 rsive) saccadic eye movements were evoked by microstimulation in anterior SC, followed by a smooth pr

110 rtant implications for the use of electrical microstimulation in both experimental and clinical setti

111 Finally, microstimulation in CGp following risky choices promoted

112 havioral thresholds for detecting electrical microstimulation in different cortical areas in two monk

113 Neurochemical microstimulation in different parts of the midbrain peri

114 e was evoked to one of the moving targets by microstimulation in either the frontal eye field (FEF) o

115 d to the human median nerve via percutaneous microstimulation in four intact subjects and via implant

116 Here, we applied microstimulation in frontal cortical areas in marmosets

117 rature on the effects of cortical electrical microstimulation in perceptual and decision-making tasks

118 found in parietal areas, nor in PFC, whereas microstimulation in posterior parietal cortex did activa

119 duce neural plasticity [10, 11], and caudate microstimulation in primates has been shown to accelerat

120 Prolonged microstimulation in RF, a larger anterior subregion of v

121 White matter microstimulation in sagittal slices (near the ventricula

122 In this study, we used electrical microstimulation in select nuclei of the avian song syst

123 Moreover, delivering microstimulation in the caudate during the reinforcement

124 arm movements can be elicited by electrical microstimulation in the deep layers of the lateral SC an

125 These perturbations are induced by brief microstimulation in the deep superior colliculus (dSC).

126 Electrical microstimulation in the forebrain gaze control area, the

127 were evoked after contralateral intraspinal microstimulation in the gray matter (cISMS; 300 muA maxi

128 ley evoked in the sural nerve by intraspinal microstimulation in the L4/5 spinal segment was increase

129 this, we measured the effects of electrical microstimulation in the lateral intraparietal area (LIP)

130 cts of optogenetic activation and electrical microstimulation in the lateral intraparietal area durin

131 re cell-targeted optogenetics and electrical microstimulation in the macaque monkey brain to function

132 Here, we show that electrical microstimulation in the monkey caudate nucleus influence

133 We show that electrical microstimulation in the motion-sensitive middle temporal

134 We show that song-triggered microstimulation in the output nucleus of the AFP induce

135 Here, we report that microstimulation in the prefrontal cortex (PFC) modulate

136 of invisible moving targets using electrical microstimulation in the prefrontal cortex.

137 Microstimulation in the right entorhinal area during lea

138 t vergence eye movements can be evoked using microstimulation in the rSC.

139 e is known about the influence of electrical microstimulation in the SC on the initiation and traject

140 Here, we applied microstimulation in the SN of 11 patients undergoing dee

141 We recorded from single units and delivered microstimulation in the striatum of rhesus monkeys perfo

142 f the interceptive saccade is perturbed by a microstimulation in the superior colliculus.

143 Microstimulation in these locations produced a variety o

144 Notably, microstimulation in this subzone, but not elsewhere in t

145 reas' activity following thalamic electrical microstimulation in tree shrews, using optical imaging a

146 Microstimulation in V1 elicited gamma-oscillations in V4

147 s and that attention increased the effect of microstimulation in V1 on the firing rates of MT neurons

148 Here, we use electrical microstimulation in V1 paired with recording in MT to pr

149 1 elicited gamma-oscillations in V4, whereas microstimulation in V4 elicited alpha-oscillations in V1

150 AGF microstimulation increases the responsiveness of OT neur

151 ain mapping experiments involving electrical microstimulation indicate that the primary motor cortex

152 Instead, microstimulation induced a variety of changes in the tim

153 xperimentally, we found that spike-triggered microstimulation induced cortical plasticity, as shown b

154 Finally, intracortical microstimulation induces activation of only contralatera

155 perceptual responses elicited by intraneural microstimulation (INMS) of single mechanoreceptive affer

156 this question have proven difficult because microstimulation interferes with electrophysiological re

157 Typically, microstimulation is applied to local brain regions as a

158 Electrical microstimulation is known to induce neural plasticity [1

159 difference in effectiveness of intracortical microstimulation is that long trains activate much large

160 Electrical microstimulation is used widely in experimental neurophy

161 both direct neural recordings and electrical microstimulation, Joshi et al. (2016) show that locus co

162 omly selected for perilesional intracortical microstimulation mapping and tissue sampling for Western

163 esult of NPT, as revealed with intracortical microstimulation mapping.

164 uscle activity patterns elicited by cortical microstimulation matched those extracted from natural mo

165 Microstimulation may cause cortical changes that could e

166 Intracortical microstimulation, Micro-PET and histological analysis we

167 pped the stimulus locations and measured how microstimulation modulated these contrast response funct

168 When the microstimulation moves the eyes in the direction opposit

169 Microstimulation never directly evoked saccades, nor did

170 e paired task-irrelevant visual stimuli with microstimulation of a dopaminergic center, the ventral t

171 Unitary EPSPs, evoked by microstimulation of a single ganglion cell, were measure

172 to keep their gaze fixed, we tested whether microstimulation of a specific location in the SC spatia

173 Consistent with this observation, microstimulation of AL, but not ML, systematically biase

174 Microstimulation of direction columns in the middle temp

175 We found that microstimulation of face patches caused increased fMRI a

176 We asked how electrical microstimulation of face patches in macaque inferotempor

177 We combined electrical microstimulation of functionally specific groups of neur

178 visual stimuli result from focal electrical microstimulation of gaze control centres in monkeys.

179 gical progress it has been demonstrated that microstimulation of infragranular cortical layers with p

180 ebellum to localize synchronous responses to microstimulation of its cortical layers and reveal the c

181 Microstimulation of layer VI in "matched" (homologous) b

182 ion, we trained animals to detect electrical microstimulation of local V1 sites.

183 y electrophysiology using chronic electrical microstimulation of macaque VTA (VTA-EM).

184 Weak microstimulation of many sites in the supplementary eye

185 Combining patterned optical microstimulation of MOB with in vivo electrophysiologica

186 In the fine task, we find that electrical microstimulation of MT does not affect perceptual decisi

187 Hz) band, and that low-frequency electrical microstimulation of pIC elicited LOB and Pica.

188 pressure, and timing--through intracortical microstimulation of primary somatosensory cortex.

189 Here we show that microstimulation of spatially aligned FEF representation

190 animals to become expert at the detection of microstimulation of specific V1 sites that corresponded

191 Microstimulation of the AGF enhanced the visual and audi

192 ation throughout the face-processing system; microstimulation of the body patches gave similar result

193 We examined whether microstimulation of the dorsal lateral geniculate nucleu

194 We used electrical microstimulation of the dPul while monkeys performed sac

195 Subthreshold microstimulation of the FEF enhances the responses of ar

196 embled that evoked by subsaccadic electrical microstimulation of the FEF.

197 over time but was transiently restored after microstimulation of the FEF.

198 terrupted decision formation with electrical microstimulation of the frontal eye field, causing an ev

199 voluntary saccades were evoked by electrical microstimulation of the frontal eye field.

200 irection of saccades evoked by intracortical microstimulation of the frontal eye fields at variable t

201 Consistent with this idea, microstimulation of the frontal eye fields, one of sever

202 roduced by voluntary attention as well as by microstimulation of the frontal eye fields.

203 Microstimulation of the granule cell layer of both trans

204 ls and multiunit neuronal activity evoked by microstimulation of the inferior olive in Postnatal Day

205 Pupil size increased transiently after microstimulation of the intermediate SC layers (SCi) and

206 on a computer screen (optically) or through microstimulation of the lateral geniculate nucleus (elec

207 Moore described how subthreshold electrical microstimulation of the macaque frontal eye fields (FEF)

208 qualitatively similar to that evoked by weak microstimulation of the midbrain superior colliculus.

209 euron, present provocative data showing that microstimulation of the precentral cortex evokes complex

210 Single stimulus intracortical microstimulation of the primary motor cortex (M1) in awa

211 Here, we show that low-level electrical microstimulation of the primate frontal eye fields (FEFs

212 We show that microstimulation of the rhesus macaque FEF alters the ma

213 Graded electrical microstimulation of the RVM at different postnatal ages

214 We combined electrical microstimulation of the striatum with simultaneous elect

215 In contrast, microstimulation of the superficial SC layers did not ca

216 Microstimulation of this cluster caused an increase in t

217 armacological inactivation and/or electrical microstimulation of various sites afferent and efferent

218 In this study, electrical microstimulation of VIP, but not of surrounding tissue,

219 devices and to further study the effects of microstimulation on the cortex, we stimulated and record

220 stimulation and was reliable within 40 ms of microstimulation onset, indicating a direct influence of

221 hindlimb (HL) cortex (based on intracranial microstimulation), or their bordering regions were relat

222 f fMRI activity patterns selectively for the microstimulation-paired stimulus.

223 nveyed to the brain through the interplay of microstimulation patterns delivered to multiple electrod

224 lerating, accelerating, and randomly varying microstimulation patterns on the likelihood and metrics

225 Surprisingly, when identical microstimulation patterns were delivered during an unrel

226 The monkeys learned to discriminate microstimulation patterns, and their ability to learn ne

227 Microstimulation produced predictable visual percepts, s

228 We demonstrate that microstimulation produces a temporally stereotyped chang

229 We applied a simple neuroprosthetic microstimulation protocol to a pair of electrodes in the

230 dings of this study suggest that even simple microstimulation protocols can be used to increase somat

231 be beneficial for this purpose, appropriate microstimulation protocols have not been developed.

232 Our results demonstrate that the pattern of microstimulation pulses strongly influences the probabil

233 Microstimulation quickened decisions in favor of the pre

234 kes with temporally and spatially structured microstimulation reliably altered the response patterns

235 ct set of afferent and efferent connections, microstimulation responses, and lesion outcomes.

236 Furthermore, electrical microstimulation resulted in highly unnatural spatial ac

237 Further, microstimulation rotates the angular preference of VPM n

238 Without microstimulation, saccades to a moving grating are biase

239 ine how neuromodulation, short-burst tetanic microstimulation (sbTetMS), alters multiregional network

240 tially unfamiliar multichannel intracortical microstimulation signal, which provided continuous infor

241 Electrical microstimulation significantly biased monkeys' heading p

242 location in space as that represented at the microstimulation site in the AGF.

243 We found that microstimulation sparsely activates neurons around the e

244 We found that microstimulation strongly distorted face percepts and th

245 to both whisker deflection and intracortical microstimulation, suggesting that the infrared represent

246 At the same time, AGF microstimulation suppressed the responsiveness of OT neu

247 Microstimulation systematically biased monkeys' choices

248 Electrical microstimulation targeted at LGN konio layers revealed t

249 episodic memory in humans, we implemented a microstimulation technique that allowed delivery of low-

250 Intracortical microstimulation techniques (ICMS) guided the injection

251 Intracortical microstimulation techniques (ICMS) were used in four exp

252 We use both single-unit recording and microstimulation techniques in monkey to answer this que

253 ed paired-pulse protocols with intracortical microstimulation techniques in sedated female cebus monk

254 within M1, we used long-train intracortical microstimulation techniques to evoke movements from the

255 ic (EMG) activity is a form of intracortical microstimulation that enables documentation in awake ani

256 We further demonstrate by microstimulation that LPP is connected with extrastriate

257 macaque frontal eye field and use electrical microstimulation to assess whether optical perturbation

258 ll-type-specific optogenetics and electrical microstimulation to characterize the koniocellular genic

259 lts support potential future applications of microstimulation to correct maladaptive plasticity under

260 questions, we combined fMRI with electrical microstimulation to determine the effective connectivity

261 We used microstimulation to directly activate pairs of sites in

262 otor cortex was explored using intracortical microstimulation to evoke forelimb movements.

263 a combination of single-cell recordings and microstimulation to explore the organization of its topo

264 We used physiological microstimulation to identify pulvinar neurons belonging

265 We used intracortical microstimulation to map motor cortex in two NTX groups:

266 We used adaptive optics microstimulation to measure psychophysical detection thr

267 Here we applied electrical microstimulation to motor cortical areas of rhesus macaq

268 of self-motion direction, we used electrical microstimulation to perturb activity in VIP while animal

269 Here, we use microstimulation to probe the role of SMA across a range

270 ly, increased attention has focused on using microstimulation to restore functions as diverse as soma

271 We also discuss potential applications of microstimulation to studies of higher cognitive function

272 We used half-second trains of intracortical microstimulation to study the functional organization of

273 nal to control the application of electrical microstimulation to the OFC.

274 We applied subthreshold microstimulation to the SC while monkeys performed a tas

275 eir gaze fixed, we delivered weak electrical microstimulation to the SC, so that saccadic eye movemen

276 sets with 96-channel Utah arrays and applied microstimulation trains while they freely viewed video c

277 atients performed a person recognition task, microstimulation was applied in a theta-burst pattern, s

278 After recordings, microstimulation was applied to compare sensory and moto

279 Electrical microstimulation was applied to the motor cortex using a

280 The modulation of choice behavior using microstimulation was best modeled as resulting from chan

281 Learning effects were observed when microstimulation was delivered during the initiation of

282 Microstimulation was less effective in shifting perceptu

283 Intracortical microstimulation was used to identify injection sites an

284 Electrical microstimulation was used to study primary motor and pre

285 ostsynaptic potentials evoked by intrabulbar microstimulation, was modulated by respiration.

286 Using microstimulation we employed an explicit experimental co

287 Using intracortical microstimulation, we determined whether the supplementar

288 ing spatiotemporal patterns of intracortical microstimulation, we find that reaction time increases s

289 with multi-electrode recording and cortical microstimulation, we probed pACC function as monkeys per

290 By contrast, electrical microstimulation, which allows the experimenter to manip

291 es toward the stimulated RF were faster with microstimulation, while choices in the opposite directio

292 Pairing VTA microstimulation with a task-irrelevant visual stimulus

293 Moreover, pairing VTA microstimulation with a task-irrelevant visual stimulus

294 detect activation of their FEF by electrical microstimulation with currents below those that cause ey

295 TEMENT Previous studies combining electrical microstimulation with functional imaging showed an inter

296 By combining adaptive optics microstimulation with high-speed eye tracking, we show t

297 (PPC) in galagos identified by intracortical microstimulation with long stimulus trains ( approximate

298 These results suggest that microstimulation with physiologic level currents-a radic

299 Thus, microstimulation within separate zones of cortex elicite

300 Here, we used microstimulation within the motor cortex of freely behav