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1 tubulin tyrosination cycle in regulating the microtubule cytoskeleton.
2 llapse of the ER network onto the underlying microtubule cytoskeleton.
3 at the flows reflect the architecture of the microtubule cytoskeleton.
4 coordinating the remodeling of the actin and microtubule cytoskeleton.
5 dependent on the function of their actin and microtubule cytoskeleton.
6 transport of intracellular cargoes along the microtubule cytoskeleton.
7 correct deployment of the apical complex and microtubule cytoskeleton.
8 is an essential step in the formation of the microtubule cytoskeleton.
9 ciate with the nuclear envelope (NE) and the microtubule cytoskeleton.
10 h associate with membranes and the actin and microtubule cytoskeleton.
11 o the cell surface was mediated by the actin-microtubule cytoskeleton.
12 lin expression to adjust the behavior of the microtubule cytoskeleton.
13 cess involves rebuilding the entire neuronal microtubule cytoskeleton.
14 le hook orientation via interaction with the microtubule cytoskeleton.
15 he other PAR proteins to polarize the oocyte microtubule cytoskeleton.
16 s a critical role in the organization of the microtubule cytoskeleton.
17 in regulating the organization of the oocyte microtubule cytoskeleton.
18 ds to marked instability of the radial glial microtubule cytoskeleton.
19 le is to provide a point of anchoring to the microtubule cytoskeleton.
20 eneoplastic cells may involve changes in the microtubule cytoskeleton.
21 rest, presumably owing to alterations in the microtubule cytoskeleton.
22 rotubules are the signature of the dendritic microtubule cytoskeleton.
23 replace the missing axon by rearranging the microtubule cytoskeleton.
24 ses kinesin motility to maintain a polarized microtubule cytoskeleton.
25 C to promote polarized reorganization of the microtubule cytoskeleton.
26 our knowledge, role in the regulation of the microtubule cytoskeleton.
27 ery little is known about how they alter the microtubule cytoskeleton.
28 o ensure that the cells entered G1 without a microtubule cytoskeleton.
29 ommunication between the cell cortex and the microtubule cytoskeleton.
30 creased fraction of tubulin to appear in the microtubule cytoskeleton.
31 ealed an association of arginase II with the microtubule cytoskeleton.
32 c reticulum membrane and associates with the microtubule cytoskeleton.
33 g for directed secretion along the polarized microtubule cytoskeleton.
34 t the centrosome and this requires an intact microtubule cytoskeleton.
35 and Dlg1 is required for polarization of the microtubule cytoskeleton.
36 d each involves repolarization of the T-cell microtubule cytoskeleton.
37 ion with the stabilization of the underlying microtubule cytoskeleton.
38 nd manifest disorganization of the root hair microtubule cytoskeleton.
39 st alpha-tubulin, which exhibit a simplified microtubule cytoskeleton.
40 and gurken mRNAs and the organization of the microtubule cytoskeleton.
41 SCG10-mediated regulation of the growth cone microtubule cytoskeleton.
42 n-mediated signaling and the dynamics of the microtubule cytoskeleton.
43 on of a single flagellum and a subpellicular microtubule cytoskeleton.
44 nt in regulating the complex dynamics of the microtubule cytoskeleton.
45 d RNAs necessary for the polarisation of the microtubule cytoskeleton.
46 and proteins and in the organization of the microtubule cytoskeleton.
47 the interaction between mitochondria and the microtubule cytoskeleton.
48 require interaction of the dynamic actin and microtubule cytoskeleton.
49 proteins, and signaling molecules along the microtubule cytoskeleton.
50 ases, vesicle trafficking, and the actin and microtubule cytoskeleton.
51 icated in DS and ASDs, as a regulator of the microtubule cytoskeleton.
52 y natural products to target and perturb the microtubule cytoskeleton.
53 atory polarity, and centrosomes organize the microtubule cytoskeleton.
54 tracellular transport, and regulation of the microtubule cytoskeleton.
55 ar processes that are dependent on a dynamic microtubule cytoskeleton.
56 ects specific functional requirements of the microtubule cytoskeleton.
57 gulates the organization and dynamics of the microtubule cytoskeleton.
58 s an important role in the regulation of the microtubule cytoskeleton.
59 y reinforcing their link with the underlying microtubule cytoskeleton.
60 enkorper, respectively, depends on actin and microtubule cytoskeletons.
61 growth and are independent of the actin and microtubule cytoskeletons.
62 en implicated in regulation of the actin and microtubule cytoskeletons.
63 g maintenance does not require the actin and microtubule cytoskeletons.
64 pendent modulation of the synaptic actin and microtubule cytoskeletons.
65 hanges require the coordination of actin and microtubule cytoskeletons.
66 pupal cells and is mediated by the actin and microtubule cytoskeletons.
67 nd morphogenesis by remodeling the actin and microtubule cytoskeletons.
68 uring meiosis in integrating the F-actin and microtubule cytoskeletons.
69 ace expression required functional actin and microtubule cytoskeletons.
70 amics and organization of both the actin and microtubule cytoskeletons.
71 hoA activation, alterations in the actin and microtubule cytoskeleton affecting neuronal morphology,
73 and the Tea cell-end marker proteins of the microtubule cytoskeleton, along with specific kinesins a
75 larity involves both a reorganization of the microtubule cytoskeleton and a change in tubulin PTMs.
77 BMP signaling is also necessary for a normal microtubule cytoskeleton and axonal transport; analysis
78 n hippocampal neurons and then disrupted the microtubule cytoskeleton and caused neuritic degeneratio
80 ive binding sites for both the actin and the microtubule cytoskeleton and could thus mediate crosstal
81 monstrate that disorganization of the T cell microtubule cytoskeleton and defects in hMunc13-4 or Rab
82 couples the membrane fusion machinery to the microtubule cytoskeleton and demonstrate that Munc18-2 a
83 passing the normal requirement for an intact microtubule cytoskeleton and for microtubule-dependent p
84 the core of centrosomes, which organize the microtubule cytoskeleton and form the poles of the mitot
85 We also show that the connection between the microtubule cytoskeleton and HIF-1alpha regulation is lo
86 bing and involves disruption to the platelet microtubule cytoskeleton and inflation through fluid ent
87 a mechanistic link between disruption of the microtubule cytoskeleton and inhibition of tumor angioge
88 metric network associated with the polarized microtubule cytoskeleton and is concentrated with transl
89 rotein that interacts with and regulates the microtubule cytoskeleton and is required for neuronal mi
91 presynaptic motoneuron disrupts the synaptic microtubule cytoskeleton and leads to disassembly of the
92 g, which results in local disassembly of the microtubule cytoskeleton and loss of axonal transport in
95 ervous system cells sense injury using their microtubule cytoskeleton and respond by dividing to repl
96 ide good evidence that SI signals target the microtubule cytoskeleton and suggest that signal integra
97 sion bodies by a process requiring an intact microtubule cytoskeleton and the cytoplasmic deacetylase
98 a forward genetic screen, we showed that the microtubule cytoskeleton and the JIP3 protein UNC-16 exe
100 xyloglucan affects both the stability of the microtubule cytoskeleton and the production and patterni
101 h atypical PKC, and that both the acetylated microtubule cytoskeleton and the Vangl2-VAMP1 distributi
103 ere, we examine the interactions between the microtubule cytoskeleton and Wnt/PCP signaling during ze
104 PCP signaling influences the polarity of the microtubule cytoskeleton and, conversely, microtubules a
106 view addresses connections between the actin/microtubule cytoskeletons and organelles in animal cells
107 llular calcium, and intact microfilament and microtubule cytoskeletons and were independent of Rho/Rh
108 (1) They build centrosomes that organize the microtubule cytoskeleton, and (2) they template cilia, m
109 ng the spatial organization of the actin and microtubule cytoskeleton, and biasing the directionality
110 translational silencing, polarization of the microtubule cytoskeleton, and posterior localization of
114 ns between membrane-bound organelles and the microtubule cytoskeleton are crucial to establish, maint
115 The integrity and dynamic properties of the microtubule cytoskeleton are indispensable for the devel
118 ly, our work demonstrates that the actin and microtubule cytoskeletons are coordinated during cytokin
119 codazole, suggesting that both the actin and microtubule cytoskeletons are important for invasion.
121 dy development requires an intact fusome and microtubule cytoskeleton as it is blocked by mutations i
122 of nuclei, centrosomes, chromosomes, and the microtubule cytoskeleton as well as the particular sensi
123 are potential coordinators of the actin and microtubule cytoskeletons, as they can both nucleate act
124 cooperative reorganization of the actin and microtubule cytoskeletons, as well as the turnover of ce
125 p35, which, in turn, modulate the actin and microtubule cytoskeleton assembly and enable newly gener
126 ndicated a synergistic decrease of actin and microtubule cytoskeleton-associated proteins in both con
127 nd ORB proteins are required to organise the microtubule cytoskeleton at stage 9, and to prevent prem
128 sruption, indicating that IRS-2 requires the microtubule cytoskeleton at the level of downstream effe
131 cleus to the anterior side along a polarized microtubule cytoskeleton, but this mechanism has not bee
132 coordinates regulation of the actin and the microtubule cytoskeleton by binding and activating the W
133 EB1 is key factor in the organization of the microtubule cytoskeleton by binding to the plus-ends of
134 mutations that contribute to or modulate the microtubule cytoskeleton by causing perturbations of neu
135 eas MCAK promotes rapid restructuring of the microtubule cytoskeleton by making catastrophe a first-o
136 though it has long been appreciated that the microtubule cytoskeleton can be post-translationally mod
137 pendent on Pak activity, suggesting that the microtubule cytoskeleton can be regulated through inacti
138 hese contact lenses also prevented actin and microtubule cytoskeleton changes typically induced by UV
139 ich it maintains a balance between actin and microtubule cytoskeleton components, thereby contributin
140 r disrupt microtubules reveal that an intact microtubule cytoskeleton contributes to IRS-2- but not I
142 icate that upon injury, the integrity of the microtubule cytoskeleton controls cell division in the C
143 morphogenesis to determine how the actin and microtubule cytoskeletons cooperate to pattern the cell
144 ryotes, the organization and function of the microtubule cytoskeleton depend on the allocation of dif
145 tion to serving as tracks for transport, the microtubule cytoskeleton directs intracellular trafficki
146 genesis, when the polarisation of the oocyte microtubule cytoskeleton directs the localisation of bic
147 e of actin assembly, and perturbation of the microtubule cytoskeleton disrupts this zone as well as l
149 e imaging to show a novel arrangement of the microtubule cytoskeleton during apical constriction: med
151 ractions occur between Wnt/PCP signaling and microtubule cytoskeleton during C&E gastrulation movemen
153 inding protein Shroom3 as a regulator of the microtubule cytoskeleton during epithelial morphogenesis
154 s to interfere with the reorientation of the microtubule cytoskeleton during healing of wounded NIH3T
155 ssociated Futsch to control stability of the microtubule cytoskeleton during nervous system developme
156 ches have implicated genes that regulate the microtubule cytoskeleton during neuronal division, migra
157 n coordinating the dynamics of the actin and microtubule cytoskeletons during directional motility of
158 sion and expansion via downstream effects on microtubule cytoskeleton dynamics and auxin signaling, t
161 vering events entail focal disruption of the microtubule cytoskeleton, followed by thinning of the di
162 pathic, exhibiting structural defects in the microtubule cytoskeleton, Golgi complex, and mitochondri
167 e loss, suppression, or stabilization of the microtubule cytoskeleton has been widely reported to cau
168 n this process, the apparent polarity of the microtubule cytoskeleton has pointed instead to roles fo
170 ization occurs in the absence of a polarized microtubule cytoskeleton, i.e. in grk null mutants, but
172 2 modulates the organization and dynamics of microtubule cytoskeleton in a Ca(2+)-independent manner
173 drugs or genetic mutations that disrupt the microtubule cytoskeleton in a Saccharomyces cerevisiae m
179 tion by a Ras homolog, R-Ras, stabilizes the microtubule cytoskeleton in endothelial cells leading to
180 ifferentiation-specific rearrangement of the microtubule cytoskeleton in epidermis, and defines an es
182 portance of tubular ER interactions with the microtubule cytoskeleton in hereditary spastic paraplegi
184 roteins that control the organization of the microtubule cytoskeleton in interphase and mitosis.
185 outcomes, we assessed the involvement of the microtubule cytoskeleton in IRS-dependent signaling.
186 , spatiotemporally precise modulation of the microtubule cytoskeleton in living cells, and promise ne
187 unexpected interdependence of DAPK-1 and the microtubule cytoskeleton in maintenance of epidermal int
188 -115) is a ubiquitous MAP that organizes the microtubule cytoskeleton in mitosis and neuronal branchi
189 this study, we investigated the role of the microtubule cytoskeleton in modulating myofibroblast phe
190 n Drosophila causes an aberrantly stabilized microtubule cytoskeleton in neurons and defects in synap
192 evere alterations in the organization of the microtubule cytoskeleton in the absence of Par6alpha and
193 iation with both the plasma membrane and the microtubule cytoskeleton in the growth cone by live cell
196 s demonstrate the striking difference of the microtubule cytoskeleton in the lamella as compared with
198 ndence of Vangl2, VAMP1, aPKC and the stable microtubule cytoskeleton in the oocyte, shows that mater
200 then document defects in both the actin and microtubule cytoskeletons in dia mutant nerve terminals.
201 Migrating cells reorganize their actin and microtubule cytoskeletons in response to external cues.
202 d, loss of hDia1 led to perturbations in the microtubule cytoskeleton, including the targeting of mic
203 ore recent advances in understanding how the microtubule cytoskeleton influences mammalian neural ste
204 activity might be expected to break down the microtubule cytoskeleton, inhibiting these enzymes in vi
205 r mammalian somatic cells, the importance of microtubule cytoskeleton integrity during interphase cel
206 In all eukaryotes, morphogenesis of the microtubule cytoskeleton into a bipolar spindle is requi
208 differentiation, many cells reorganize their microtubule cytoskeleton into noncentrosomal arrays.
209 during this process is the remodeling of the microtubule cytoskeleton, involving disassembly of the c
214 ere, we investigated whether the pollen tube microtubule cytoskeleton is a target for the SI signals.
215 dependent forces as it still occurs when the microtubule cytoskeleton is compromised but is blocked w
222 sis of normal duration, the integrity of the microtubule cytoskeleton is not subject to checkpoint su
224 have identified a novel pathway by which the microtubule cytoskeleton is regulated during sublethal c
225 s transition from interphase to mitosis, the microtubule cytoskeleton is reorganized to form the mito
227 of polymerized tubulin, not dynamics of the microtubule cytoskeleton, is crucial for convergent exte
229 s, which disrupts organelle transport on the microtubule cytoskeleton, is likely to be the primary di
230 powerful chemotherapy agents that target the microtubule cytoskeleton, leading to mitotic arrest and
231 nd/or the coordination between the actin and microtubule cytoskeletons, leading to motor neuron degen
233 differential expression of genes involved in microtubules, cytoskeleton linkages, and motor activity.
234 A, or roscovitine resulted in changes in the microtubule cytoskeleton, loss of cellular polarity, and
235 r with the signaling data, suggests that the microtubule cytoskeleton may facilitate access of IRS-2
236 how proteins linking pairing centers and the microtubule cytoskeleton mediate homolog pairing and res
240 f centrosomes, which organize the interphase microtubule cytoskeleton of most animal cells and form t
242 ogenitors, their astroglial progeny, and the microtubule cytoskeleton of these cells in the developin
244 o not fill the axonal cytoplasm, disrupt the microtubule cytoskeleton, or affect the transport of syn
247 g from both isoforms intersects in actin and microtubule cytoskeletons, our results suggest that KRas
252 erprolin homologous protein) complex and the microtubule cytoskeleton promote STIM 1 clustering at si
256 novel roles for vertebrate Dchs in actin and microtubule cytoskeleton regulation in the unanticipated
258 inhibitors are prime reagents for studies in microtubule cytoskeleton research, being applicable acro
259 we show that the FTI lonafarnib affects the microtubule cytoskeleton resulting in microtubule bundle
260 e assembly and organization of the actin and microtubule cytoskeletons, Rho and Cdc42 make several ke
261 ER shaping and network interactions with the microtubule cytoskeleton seem to be the predominant path
264 they traffic to the oocyte along a polarized microtubule cytoskeleton shared by the entire cyst.
265 ing mechanisms; (ii) a negative regulator of microtubule cytoskeleton stability; and (iii) a negative
266 y nocodazole-induced depolymerization of the microtubule cytoskeleton, suggesting that mCCCAP is an i
268 crotubule-nucleating site that regulates the microtubule cytoskeleton temporally and spatially throug
269 iotemporal organization are hallmarks of the microtubule cytoskeleton that allow formation of complex
270 NA to the oocyte posterior along a polarised microtubule cytoskeleton that grows from non-centrosomal
272 ections from the cell surface that contain a microtubule cytoskeleton, the ciliary axoneme, surrounde
273 involve coordinated changes in the actin and microtubule cytoskeletons, this novel function for APC a
274 dynamics and reorganization of the actin and microtubule cytoskeleton through signaling pathways link
275 onstrate spatial asymmetry in the underlying microtubule cytoskeleton throughout the cell division cy
277 rane trafficking pathways cooperate with the microtubule cytoskeleton to give rise to the primary cil
278 rane proteins and spectrin to the underlying microtubule cytoskeleton to organize and stabilize the p
280 This suggests that MAP7 links Kif5b to the microtubule cytoskeleton to promote nuclear positioning.
281 d spatially regulated communication from the microtubule cytoskeleton to the actin cytoskeleton and t
282 ed role of APC2 in integrating the actin and microtubule cytoskeletons to mediate cellular morphologi
283 lays a key role in integrating the actin and microtubule cytoskeletons to position centrosomes and mi
285 f the salivary glands in the fly embryo, the microtubule cytoskeleton undergoes major rearrangements,
287 mber of essential pathways converge upon the microtubule cytoskeleton, understanding how cells utiliz
290 results were obtained for cells in which the microtubule cytoskeleton was partially diminished by low
292 the perinuclear region requires a functional microtubule cytoskeleton, whereas clustering of these co
293 istribution after disruption of the cellular microtubule cytoskeleton with high statistical significa
294 were accompanied by a redistribution of the microtubule cytoskeleton with increased numbers of micro
295 d function requires tight integration of the microtubule cytoskeleton with membrane trafficking, and
297 chondria positioning appear dependent on the microtubule cytoskeleton, with kinesin or dynein motors
299 associated with disruption of the actin and microtubule cytoskeleton within the yolk cell and defect