コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 asurements have been made using exchangeable mimics of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholi
2 As a result, the Gh lesion, as a functional mimic of a 1,2-intrastrand crosslink, occupies canonical
4 We further show, by using both an in vitro mimic of a crowded cellular environment and eukaryotic c
5 inuation of a previous study, a spin-labeled mimic of a glycan acceptor ligand is used to identify ad
6 between this same sterol and an exchangeable mimic of a high-melting phospholipid in liquid-ordered b
7 oteins in a second mechanism by which the WS mimic of a Legionella environmental niche can reverse vi
8 ble mimic of cholesterol and an exchangeable mimic of a low-melting phospholipid in liquid-disordered
11 e mechanisms using antisense oligonucleotide mimics of a pause RNA hairpin from the leader region of
12 seagrasses via sediment stabilization, while mimics of aboveground plant structures most facilitate m
13 was applied to histone proteins to install a mimic of acetylated lysine (KAc, an epigenetic marker).
20 out the backbone, are emerging as structural mimics of alpha-helix-forming conventional peptides (com
21 roach to lipophilicity determination using a mimic of an alkyl alcohol with compound partitioning qua
23 e carboxyl-terminal domain of TaiP exposes a mimic of an eukaryotic ATG16L1-binding motif that binds
25 port polyproline as a minimum (bio)synthetic mimic of antifreeze proteins that is accessible by solut
28 change model on microplastics in a gut fluid mimic of aquatic biota, and also included food to provid
29 we report that a stable synthetic thioether mimic of AspH substrates can be employed in solid phase
32 m natural and synthetic amphiphiles serve as mimics of biological membranes and enable the delivery o
33 the candidacy of glycodendrimersomes as new mimics of biological membranes with programmable glycan
36 alt interactions with butyramide as a simple mimic of cation interactions with protein backbones.
37 protein 1 (LMP1) is an EBV-encoded oncogenic mimic of CD40 that can be re-expressed in PBMCs during S
39 ipid monolayers were employed as a simple 3D mimic of cellular compartments to reconstitute Min prote
41 YIK-amide, have been coupled to exchangeable mimics of Chol (cholesterol) and Phos (1,2-dipalmitoyl-s
42 pulsive interactions between an exchangeable mimic of cholesterol and an exchangeable mimic of a low-
44 +) blockage property, we engineered a set of mimics of CNG channel pores for both structural and func
47 opic investigations on a series of synthetic mimics of cytP450 indicate that a thiolate-bound ferric
49 odel hydrophobic- and hydrophilic-rich phase mimics of dentin adhesive polymerize similarly and 2) to
51 2-O-tetradecanoylphorbol-13-acetate (TPA), a mimic of diacylglycerol and PKC activator), hypertonic s
53 restriction) from bacteriophage T7 acts as a mimic of DNA and inhibits all Type I restriction/modific
55 eered nanostructures could provide effective mimics of ECM for investigation and control of the initi
56 secreted peptides that function as molecular mimics of endogenous plant peptides to promote parasitis
60 plex as the fluorescent response core, a DNA mimic of fluorescent proteins was constructed, which suc
64 These sensors are based on Spinach, an RNA mimic of GFP, and they have successfully been used to im
67 we show that the P39 peptide is a structural mimic of glyceraldehyde 3-phosphate dehydrogenase (GAPDH
69 that residual attractions are present under mimics of good solvent conditions, and for NTL9 they res
72 mportantly, a synthetic exogenous soluble EL mimic of GraS protected the parental MW2 strain against
74 of various forms of Ras (loaded with GDP and mimics of GTP or nucleotide-free) at the allosteric and
76 l nucleophiles generated biologically active mimics of H3 with posttranslational modifications includ
77 e hypothesized that a synthetic nanoparticle mimic of HDL (HDL NP) that binds SR-B1 and removes chole
78 m, we tested a library of small, nonpeptidic mimics of HDPs (smHDPs) and identified compounds that ki
80 the most promising antigenic and structural mimics of HIV-1 Env is the SOSIP.664-stabilized soluble
82 d residues can serve as effective structural mimics of homologous alpha-amino acid residues within a
85 and programmed cell death are manipulated by mimics of host proteins encoded by pathogenic bacteria.
88 ations for the use of cell lines as faithful mimics of in vivo epigenetic and physiological processes
89 t type 1 IP(3)R (IP(3)R1) revealed that 6, a mimic of Ins(4,5)P(2), is only 4-fold less potent than I
91 singly, we found that K16Q mutation in H4, a mimic of K16 acetylation, leads to a structural disorder
93 o generate specific numbers of PM mimics (PM(Mimics)) of known composition for dry, direct deposition
99 has been applied to the design of structural mimics of membrane active antimicrobial peptides (AMPs)
100 we address this problem in the context of a mimic of microRNA-122 by employing novel nucleobase and
103 rovide the first structure of an acetylation mimic of mIDH2 and new insights into the regulatory mech
105 reatment of these microglia with a synthetic mimic of miR-155 restored the inflammatory response to a
110 d whether minimally selective small molecule mimics of missing protein channels might be capable of c
112 refore, we postulate selenite is a molecular mimic of monocarboxylates which allows selenite to be tr
116 The feasibility of these novel compounds as mimics of MUC1 antigens has been validated by the X-ray
117 synthesized lipid-tethered glycopolypeptide mimics of mucins and added them to lipid bilayers, allow
119 nt approach for generating glycosulfopeptide mimics of N-terminal PSGL-1 through development of a ste
120 his report, hydrolytically stable structural mimics of N7-guanine-conjugated DPCs were generated by r
123 of the currently missing technologies is the mimic of natural photosynthesis to convert carbon dioxid
125 ical porous columns and serve as fundamental mimics of natural porous helix-forming proteins and supr
126 By in vitro screening of small molecule mimics of naturally occurring host defense peptides (HDP
127 selected for NAE activation can function as mimics of Nedd8 to form thioester conjugates with NAE an
130 d also exhibits an impressive potential as a mimic of nucleosides, carbohydrates, PNA, amino acids, a
131 ydrolytically stable and accurate structural mimic of O-GlcNAc that can be encoded in mammalian syste
133 ed enzymes that are supplied with cyanide, a mimic of O2 (-) Studies with CDH and its isolated heme b
134 r of NifEN(M) as a structural and functional mimic of one catalytic alphabeta-half of NifDK while sug
135 constructs as well as oligonucleotide-based mimics of parts of the origin to examine the initiation
139 atural products containing a C-P bond act as mimics of phosphate esters and carboxylic acids, thereby
140 t, the Hsp27 phospho-mimic is only a partial mimic of phosphorylated Hsp27, both in self-association
141 allographic structure of L-PYK with the S12D mimic of phosphorylation indicates that Cys436 is oxidiz
143 molecular photonic signal transducer and two mimics of photosynthetic photoregulatory processes are d
144 se proteins have been shown to act as ligand mimics of plant CLE peptides and are required for succes
149 ed azetidine-2-carboxylic acid (Aze), a dual mimic of proline and alanine, is activated by both human
150 hat are 1-2 nm in diameter act as functional mimics of protein channels, and have been used to explor
151 amer backbones have been described as useful mimics of protein secondary structure elements, enabling
153 chemistry is the identification of effective mimics of protein secondary structures that act as inhib
154 s suggest that rationally designed synthetic mimics of protein subdomains that target the transcripti
156 ings suggest that RaxX serves as a molecular mimic of PSY peptides to facilitate Xoo infection and th
157 ng only a single phosphocysteine (pCys) as a mimic of pThr at 180 was sufficient to switch the kinase
159 monium ions that were previously designed as mimics of several carbocations are actually better mimic
160 al feeding experiments using synthetic miRNA mimics of Sex-miR-10-1a, Sex-miR-4924, and Sex-miR-9 res
161 pt materials scientists to pursue biopolymer mimics of silk with high performance yet light weight.
162 Of particular interest is the development of mimics of small molecules with important cellular functi
165 lity of the 1:1 complex of NCp7 with a 20mer mimic of stem-loop 3 RNA (SL3, also called psi-RNA, in t
174 riments, we show that argininamide, a ligand mimic of TAR's cognate protein binding partner Tat, is a
175 action with the ligand argininamide (ARG), a mimic of TAR's cognate protein binding partner, the tran
176 These results suggest that all peptidic mimics of Tat induce the same dynamics in TAR within thi
177 ouse was initially described as a phenotypic mimic of Tetralogy of Fallot with pulmonary atresia; how
178 ere, we report the first Fe-based functional mimic of the active site of [Fe]-hydrogenase, which was
179 the step-by-step construction of a prototype mimic of the AIS that we call an adaptive immune respons
181 (EBV) protein latent membrane 2a (LMP2a), a mimic of the B cell receptor, provides constitutive surv
182 tify BRMS1 as the first eukaryote structural mimic of the bacterial IpaH E3 ligase family and establi
189 fluorogenic RNA aptamers that bind DFHBI, a mimic of the chromophore in green fluorescent protein, a
190 is noncleavable but is a partial biological mimic of the cleaved form UmuD', has been identified.
193 in the apo state and in complex with GDP, a mimic of the donor substrate, and with a glycopeptide ac
194 -peptide-HLA-B*18:01 complex is a structural mimic of the EBV peptide-HLA-B*18:01 complex, and that t
196 d formation and site-directed mutagenesis, a mimic of the enzyme.substrate complex has been trapped.
197 erol and 10 +/- 2 cm/s in a 100% cholesterol mimic of the experimentally observed noncrystalline chol
198 excited-state electron donor, a dinucleotide mimic of the FADH2 cofactor containing O at the 5'-end a
199 ate ferryl precursor, and a vanadium(IV)-oxo mimic of the ferryl intermediate in the l-arginine 3-hyd
200 Although 1C8 was designed to be a structural mimic of the fused tetracyclic indole compound IDC16 tha
201 This nucleoside was incorporated into a mimic of the glutamate receptor B (GluR B) mRNA R/G edit
202 nt Spinach aptamer, which is a synthetic RNA mimic of the Green Fluorescent Protein, from its split s
204 of such exposures, we developed an in vitro mimic of the in vivo event of exposure to PM contaminate
205 blocked by addition of synstatin, a peptide mimic of the integrin activating region present on the s
207 roaches: a truncation to generate a fragment mimic of the intermediate, and selective destabilization
209 I)-CO complex of the H103G H-NOX mutant as a mimic of the ligand-free and kinase-inhibitory Fe(II)-NO
212 n of Cys78 with maleimide creates a solution mimic of the Lys-ligated cyt c that has enhanced peroxid
213 -II, a histidine-containing branched peptide mimic of the malarial biomarker Plasmodium falciparum hi
214 s dipeptidyl-peptidase IVA (DppIVA), a close mimic of the mammalian ectopeptidase CD26, which modulat
217 us expression of MCT12 and MCT12:214Delta, a mimic of the mutant allele, were used to assess protein
218 specific analysis of a recombinant, trimeric mimic of the native HIV-1 viral spike (BG505 SOSIP.664)
219 uence is a faithful antigenic and structural mimic of the native trimer in its prefusion conformation
220 nd acts as a structurally distinct synthetic mimic of the natural ligand, flavin mononucleotide, to r
221 P450cin complexed with nitric oxide, a close mimic of the O(2) complex, shows that Gly238 is likely t
224 oglutarate dioxygenase inhibitor is a better mimic of the overall transcriptional response to hypoxia
225 hem, compounds 2 and 3 appeared to be a good mimic of the parent endogenous thyronamine, T0AM and T1A
226 ntain a sulfamide group as a nonhydrolyzable mimic of the phosphate group in the cognate Ub/Ubl-AMP a
228 ily accepted an N-acetylcysteamine thioester mimic of the reduced pentaketide product of Rdc5 to synt
229 and mammalian ribosomes and an RNA stem-loop mimic of the sarcin/ricin loop (SRL) at a higher catalyt
231 presence of the product acetate or a potent mimic of the tetrahedral intermediate were determined by
233 LMP1 is a constitutively active functional mimic of the tumor necrosis factor receptor superfamily
235 posomal nanoparticle loaded with a synthetic mimic of the tumor suppressor miRNA miR-34a as the activ
238 nate interaction through the provision of a "mimic" of the HLA-encoded peptide derived from the immun
239 erent classes of beta-lactam antibiotics, as mimics of the acyl-D-Ala-D-Ala moiety at the allosteric
241 on a possible SN1 catalytic mechanism and as mimics of the carbocation in the transition state of hUP
242 of the transmembrane helices is preserved in mimics of the cell bilayer, and that the apparent voids
243 y shown that two of these miRNAs function as mimics of the cellular miRNAs miR-155 and miR-142-3p.
245 king in S. aureus using fluorescently tagged mimics of the endogenous substrate of penicillin-binding
252 trated by experiments that created synthetic mimics of the interior cavity) or if the interior also a
253 We investigated this hypothesis by making mimics of the intermediate that are the ground-state con
255 hnology is used to create modular, synthetic mimics of the Large Latent Complex that restrains transf
256 and 2-azadecalins that are close structural mimics of the m/z 202.126 ion, and showed that they are
257 s requires experimental approaches providing mimics of the microenvironment that proteins encounter i
261 NAC) fatty acid thioesters have been used as mimics of the natural acyl carrier protein pathway inter
263 libraries may be considered to be structural mimics of the natural products pramanicin and epolactaen
264 phylococcus aureus, we show that fluorescent mimics of the natural substrate of PBPs (PG stem peptide
265 use beta-lactams are chemical and structural mimics of the natural substrate, resistance mediated by
266 s of nucleotides are considered to be useful mimics of the natural substrates, but direct structural
267 crystal structures of the Michaelis complex mimics of the PKA catalytic subunit (PKAc) were obtained
268 SIP Env trimers are structural and antigenic mimics of the pre-fusion native, surface-presented Env,
270 rene macrocycles bearing phosphines as crude mimics of the rigid backbones of proteins, we demonstrat
272 ity analyses, we designed two cyclic peptide mimics of the TAR-binding beta2-beta3 loop sequences pre
276 n an anti-HIV screen to identify structural "mimics" of the fused tetracyclic indole compound 1 (IDC1
277 reciprocally compromised the effects of the mimics of their counterparts on M. marinum intracellular
278 elming majority of studies on small-molecule mimics of these enzymes entirely ignores the contributio
284 In this work, we investigate supramolecular mimics of these systems by mixing one-dimensional assemb
285 y of 2,4-difluorotoluene (F), a low-polarity mimic of thymine (T), to form a hydrogen-bonded complex
288 e, while the phosphonyl group is a versatile mimic of transition-states, intermediates, and primary m
289 of several carbocations are actually better mimics of transition state structures for carbocation de
290 e has been probed with a series of synthetic mimics of trehalose dimycolate in binding assays, in str
294 on findings, variant anatomy, artifacts, and mimics of TVAI when evaluating cases of craniocervical t
295 orobenzimidazole, non-hydrogen bonding shape mimics of uracil and hypoxanthine, respectively, is stro
297 t or treatment with cytoplasmic poly(I:C), a mimic of viral dsRNA, activates this pathway to regulate