ライフサイエンスコーパス: minimally

1 t other alternative splicing pathways change minimally.

2 s and use of herbs increase the risk, albeit minimally.

3 or autophagy impairment but mTOR is involved minimally.

4 The 90% yield of ET to H(B) derives from (minimally) 3 P* populations with distinct means of P* de

5 drugs acting on opioid or 5-HT receptors, or minimally absorbed antibiotics (all of which are selecte

6 A priori the minimally acceptable sensitivity threshold was 90% with

7 eaked sharply at around 4 ms and varied only minimally across that group.

8 k in the unadjusted (HR = 1.25; P = 0.0145), minimally adjusted (HR = 1.23; P = 0.0417, and fully adj

9 proposed to serve a general acid-base role, minimally affect catalytic activity.

10 tensive modification of the antisense strand minimally affected 5'-phosphorylation of the siRNA by ki

11 thod predicted no effect concentrations were minimally affected by changes in the assay temperature,

12 tract on the opposite (non-injured) side was minimally affected by the injury.

13 t proteins appeared to be unaffected or only minimally affected in Cep290 mutant mice.

14 Lecithin and AP minimally affected the polymorphic form IV-to-V transiti

15 s in the Wls(fl/-);Gfap-Cre hippocampus were minimally affected, as determined by single nucleus RNA

16 We find that most parameters are minimally affected, though activation energy is impacted

17 onth dry season, rarely causing symptoms and minimally affecting the host immune response.

18 known trigger of ferroptosis that by itself minimally affects AML cells.

19 hat, if at all, the simulation box size only minimally affects both the thermodynamics and kinetics o

20 s to a reduction in lytic potential but only minimally affects cell entry.

21 gnificantly inhibits HBV infection, yet only minimally affects the ability of HDV to infect and persi

22 Collagens were minimally altered in SR-uPA(+/0) aortas and ruptured hum

23 inhibited FUS solid-phase aggregation, while minimally altering liquid-phase condensation.

24 lthough quantitative PET parameters differed minimally, an increase in noise was observed.

25 Perchlorate and tosylate are minimally basic anions that are nevertheless suitable fo

26 k we describe an alternative "non-anhydrous, minimally basic" ("NAMB") technique that simplifies the

27 who are asymptomatic, or whose symptoms are minimally bothersome and pose no apparent risk to drivin

28 of Ca(2+) to the Gla domain and is affected minimally by interaction with thrombin.

29 transfer sensors were induced by pacing and minimally by neurohormonal stimulation, providing functi

30 increased by neurohormonal stimulation, but minimally by pacing.

31 e ischemic period whereas synchrony measures minimally changed over the same recording period in surg

32 rs associated with cardiovascular death were minimally changed.

33 lth-utility HRQL, exceeding 1- to 4-fold the minimally clinically important difference across all ins

34 we observed that, while GHRH(tdTom) neurons minimally colocalize with Kiss1(hrGFP) in prepubertal mi

35 Both viruses form inclusion bodies, minimally composed of nucleoprotein (N), phosphoprotein

36 VMO-select aims to reduce gene space without/minimally compromising the sample classification efficie

37 s support a model whereby SNX3-retromer is a minimally concentrative coat protein complex adapted to

38 ion, and meso-parietal areas associated with minimally conscious and conscious states.

39 nresponsive wakefulness syndrome (VS/UWS) or minimally conscious state (MCS).

40 vioural sign that can accurately distinguish minimally conscious state from VS/UWS.

41 tribution of dopaminergic neuromodulation in minimally conscious state is undemonstrated.

42 logical and cognitive interpretation of each minimally conscious state item is still unclear and deba

43 s: (i) the current behavioural repertoire of minimally conscious state items is limited and restricte

44 In addition to enlarging the minimally conscious state items repertoire, and therefor

45 unresponsive wakefulness syndrome (UWS)-and minimally conscious state.

46 mine whether he was in a vegetative state or minimally conscious state.

47 fy non-communicating patients who are in the minimally conscious state.

48 antly discriminated between unresponsive and minimally conscious states at the group level.

49 ether the patient is unresponsive or perhaps minimally conscious(1), and to predict whether they will

50 on in biomedical research have been shown to minimally correlate with genomic expression patterns fro

51 red in mechanically plastic, nanoporous, and minimally degradable interpenetrating networks of recons

52 al cortex of non-human primates contains two minimally dependent low-dimensional subspaces: one that

53 , treatment of neonatal seizures has changed minimally despite poor drug efficacy.

54 during alveologenesis, markers for AMFs are minimally detected in the adult.

55 Here we develop a minimally disruptive optical approach to control protein

56 le-dependent structural variation of the two minimally distinct human leukocyte antigen (HLA)-B*27:05

57 10-fold higher than the clinically suggested minimally EC90 protective concentration of 24 fmol/10(6)

58 With unclear etiology and minimally effective therapies, two-thirds of IPF patient

59 oking cessation aids currently available are minimally effective, highlighting the need for novel the

60 liver-specific Slc30a10 knockouts were only minimally elevated, suggesting that another organ compen

61 Furthermore, this assay can be adopted in minimally equipped laboratories and with potential use i

62 tive EVs and bioengineered EVs has been only minimally explored in the context of cardiovascular dise

63 acterized, but infection of T cells has been minimally explored.

64 In normal resting B cells, IFITM3 was minimally expressed and mainly localized in endosomes.

65 Although the PD-1/PD-L1 pathway is minimally expressed in prostate tumors, we previously de

66 These data show that the placenta minimally expresses the canonical cell-entry mediators f

67 ng observational data that are either raw or minimally filtered (denoised without using explicit stoc

68 d environmental requirements while deviating minimally from the baseline diet among Dutch adults.

69 specificity is correlated with there being a minimally frustrated binding pocket leading to a funnele

70 , have evolved collectively to give funneled minimally frustrated landscapes but some strategic parts

71 ty for the combination was significantly but minimally higher (0.87 [0.84-0.89] vs 0.85 [0.82-0.87]).

72 during nurturing maternal behaviors, but was minimally impacted by rough handling.

73 Cluster II (28 patients) - the minimally impacted patient exhibited highest levels of s

74 selectively impairs brain tumor growth while minimally impacting mammary tumor growth.

75 ponsive to changes in quality of life with a minimally important difference of 2, with good specifici

76 Scale properties, responsiveness, and a minimally important difference were determined.

77 le extent other denervating disease but only minimally in acquired myopathies.

78 alf of the nucleosome disk participates only minimally in protein binding.

79 We found Ccr2(+) BMDMs minimally influenced br-met while CNS-myeloid promoted b

80 ed EEG features during active touch that are minimally influenced by movement type and frequency cond

81 hile knockdown of either LIMK1 or LIMK2 only minimally influenced invasion in culture, simultaneous k

82 hat potentially serves as a basis upon which minimally injurious ventilation strategies might be deve

83 novel yet simple split lens geometry that is minimally invasive (requiring a few millimeters along th

84 The minimally invasive 360-degree surgical approach with a f

85 plored in this context, and the use of novel minimally invasive ablative therapies has been proposed.

86 as extracted from 21 ADCs in situ (AISs), 27 minimally invasive ADCs (MIAs), and 54 fully invasive AD

87 a and adenocarcinomas in situ (class H1), 64 minimally invasive adenocarcinomas (class H2) and 132 in

88 treatment is a relatively novel and growing minimally invasive aesthetic skin procedure.

89 phy (PAINT) method that exploits aptamers as minimally invasive affinity probes.

90 soriasis skin, suggesting their utility as a minimally invasive alternative to biopsies for detecting

91 Tape strips are an emerging, minimally invasive alternative, but global transcriptomi

92 tem cell formulations have been developed as minimally invasive alternatives.

93 There is still an urgent need for supportive minimally invasive and cost-effective biomarkers for ear

94 xt wave of electroceutical therapies will be minimally invasive and more targeted than current approa

95 Patients undergoing minimally invasive and open colectomy consume similar am

96 ng post-discharge opioid consumption between minimally invasive and open colectomy.

97 of hydrogel-based immunoisolation presents a minimally invasive and robust cell-therapy to restore ho

98 In colorectal surgery, minimally invasive approaches are partly justified by re

99 e analyzed all types of surgery combined and minimally invasive approaches separately.

100 RAS development and to the evidence-base for minimally invasive approaches.

101 balance these risks against the benefits of minimally invasive approaches.

102 When possible, minimally invasive autopsy (MIA) was performed on partic

103 The presence of a minimally invasive azide handle assured that the sgRNAs

104 ty of bodily fluids have recently emerged as minimally invasive biomarkers for a broad range of patho

105 njectable hydrogels are highly desirable for minimally invasive biomedical therapeutics.

106 in the left anterior descending artery where minimally invasive CABG was performed, and in the corona

107 The high demand in effective and minimally invasive cancer treatments, namely thermal abl

108 Vascular embolization is a life-saving minimally invasive catheter-based procedure performed to

109 focus on blood, the most commonly collected minimally invasive clinical sample, and on the two most

110 Minimally invasive collection methods may improve access

111 ents a wearable microneedle sensor array for minimally invasive continuous electrochemical detection

112 on of wearable electrochemical sensors: from minimally invasive continuous glucose monitors for chron

113 To that end, our minimally invasive cryogels have been engineered to addr

114 tilage repair, allowing for a controlled and minimally invasive delivery of gene vectors in a spatiot

115 Microneedles (MNs), as an effective minimally invasive delivery route, when used to puncture

116 d serum as an easy, fast, non-expensive, and minimally invasive detection method for distinguishing c

117 nication, and are being studied as promising minimally invasive diagnostic markers.

118 as the potential to provide highly accurate, minimally invasive diagnostics.

119 ovative approaches have become available for minimally invasive en bloc resections of large non-pedun

120 We were able to induce stroke using minimally invasive endovascular approach and observe in

121 n (AF) treatment led to the development of a minimally invasive epicardial/endocardial ablation appro

122 omy (C-index, 0.569), or patients undergoing minimally invasive esophagectomy (C-index, 0.542); calib

123 Hybrid minimally invasive esophagectomy (HMIE) has been shown t

124 ct of direct start of oral feeding following minimally invasive esophagectomy (MIE) compared with sta

125 The introduction of minimally invasive esophagectomy (MIE) has reduced posto

126 al feeding (DOF) to standard of care after a minimally invasive esophagectomy (MIE) performed in a ce

127 imed to compare long-term survival following minimally invasive esophagectomy (MIE) versus open esoph

128 validity of the randomized TIME trial, when minimally invasive esophagectomy (MIE) was implemented n

129 Totally minimally invasive esophagectomy (TMIE) is increasingly

130 Both transthoracic and transhiatal minimally invasive esophagectomy resulted in a more exte

131 Transhiatal minimally invasive esophagectomy was accompanied with mo

132 Long-term survival after minimally invasive esophagectomy was equivalent to open

133 ve morbidity in patients undergoing open and minimally invasive esophagectomy.

134 Two incision minimally invasive fasciotomy to decompress the anterior

135 d peroneal compartment using a dual-incision minimally invasive fasciotomy.

136 gia in a fast, low-cost, non-destructive and minimally invasive fashion.

137 d and hard-to-reach body location areas in a minimally invasive fashion.

138 electronic functionality with catheters for minimally invasive forms of cardiac surgery.

139 Micro- or minimally invasive glaucoma surgeries (MIGS) have been t

140 laucoma drainage implants (GDIs), and select minimally invasive glaucoma surgeries (MIGS) including t

141 the open RH and 51 (9.1%) recurrences in the minimally invasive group (P = .43).

142 ealed an increased risk of recurrence in the minimally invasive group in propensity-matched cohort (H

143 ET as significantly mutated genes in the pre/minimally invasive group.

144 Sixty-three percent underwent minimally invasive lobectomy.

145 These microbeads can be delivered in a minimally invasive manner and form functional microvascu

146 highly suitable for administering drugs in a minimally invasive manner to the target organ(s).

147 te intradermal delivery of autoantigens in a minimally invasive manner.

148 have significant potential to revolutionize minimally invasive medical interventions in the future.

149 ed impedimetric biosensor could be used as a minimally invasive method for the diagnosis of prostate

150 amples, and serum proteomics is a useful and minimally invasive method for this purpose.

151 anescent tails of the fields, allowing for a minimally invasive method to probe the polarization with

152 scrimination of sEV-associated proteins is a minimally invasive method with potential to discriminate

153 ction and enumeration of targeted cells with minimally invasive methods, have the advantages of elect

154 undity of humpback whales via non-lethal and minimally invasive methods.

155 licability of this microneedle sensor toward minimally invasive monitoring of ketone bodies has been

156 BEST PRACTICE ADVICE 11: Minimally invasive operative approaches to the debrideme

157 Allogeneic islet transplant offers a minimally invasive option for beta cell replacement in t

158 To develop a minimally invasive optogenetic method that overcomes thi

159 nd may further facilitate the development of minimally invasive optogenetic tools for the treatment o

160 We identified 562 patients who underwent minimally invasive or open colectomy from 43 hospitals.

161 Patients undergoing minimally invasive or open, transthoracic or transhiatal

162 ion, relative to placebo, on exploratory and minimally invasive outcome measures for moderate to seve

163 rmed via an ancillary qubit, which acts as a minimally invasive probe that detects absent qubits whil

164 TCAR is a novel minimally invasive procedure for carotid revascularizati

165 Transcatheter embolization is a minimally invasive procedure that uses embolic agents to

166 Endoscopic mucosal resection (EMR) is a minimally invasive procedure used for the treatment of l

167 ed to probe the feasibility of phaco-ECPL, a minimally invasive procedure, as first-step management i

168 Once implanted through a minimally invasive procedure, the microprobe can stay wi

169 us ICH may be beneficial, in particular with minimally invasive procedures and when performed soon af

170 le and behavioral therapy, drug therapy, and minimally invasive procedures.

171 ipheral metabolic readouts primarily through minimally invasive procedures.

172 igher and disease-free survival is lower for minimally invasive radical hysterectomy than for open su

173 al and a subsequent population-level review, minimally invasive radical hysterectomy was shown to be

174 is retrospective series, patients undergoing minimally invasive radical hysterectomy, including those

175 e randomly assigned (1:1) to receive open or minimally invasive radical hysterectomy.

176 A minimally invasive renal artery injection was therefore

177 the open RH group and 18/156 (11.5%) in the minimally invasive RH group (P = .019).

178 n the open RH group and 16/182 (8.8%) in the minimally invasive RH group (P = .058).

179 en RH was performed in 255 cases (29.1%) and minimally invasive RH in 560 cases (70.9%).

180 Risk-adjusted analysis revealed that minimally invasive RH was independently associated with

181 Minimally invasive robotic-assisted surgeries have been

182 rmore, this study established the utility of minimally invasive slit aspirate method for monitoring o

183 , and macro X-ray fluorescence (MA-XRF) with minimally invasive surface-enhanced Raman spectroscopy (

184 One is Transanal Minimally Invasive Surgery (TAMIS), the other is Endosco

185 he open surgery group vs 130.0 [19.8] in the minimally invasive surgery group) or 3 months after surg

186 oup and 252 [79%] of 319 participants in the minimally invasive surgery group).

187 e open surgery group and 319 assigned to the minimally invasive surgery group.

188 tween the open surgery (129.3 [SD 18.8]) and minimally invasive surgery groups (129.8 [19.8]).

189 High quality minimally invasive surgery is challenging.

190 0.68-0.85, I(2) = 23%, 21 studies), and for minimally invasive surgery it was 0.68 (95% CI = 0.56-0.

191 .22-1.60, I(2) = 46%, 20 studies), and after minimally invasive surgery it was 1.47 (95% CI = 1.26-1.

192 can reduce adhesion formation, the effect of minimally invasive surgery on long-term adhesion-related

193 ntraventricular Hemorrhage III trial and the Minimally Invasive Surgery Plus Alteplase for Intracereb

194 No-opioid minimally invasive surgery should be the goal rather tha

195 orbital intraconal tumors were treated with minimally invasive surgery using an endonasal endoscopic

196 During videoscope-assisted minimally invasive surgery which uses a high magnificati

197 in vivo manipulation of cells or tissues and minimally invasive surgery.

198 edles around sensitive internal obstacles in minimally invasive surgery.

199 essel coronary artery disease by combining a minimally invasive surgical approach to the left anterio

200 A simplified ERP with seven key domains (minimally invasive surgical approach when feasible, pre-

201 Minimally invasive surgical approaches offer significant

202 ing review revealed that the endoluminal and minimally invasive surgical devices for GERD therapy are

203 ultimodal and multiplexing capabilities into minimally invasive surgical instruments may improve surg

204 ium, and garnet (Er,Cr:YSGG) laser (ERL) and minimally invasive surgical technique (MIST) for the tre

205 BEST PRACTICE ADVICE 12: Multiple minimally invasive surgical techniques are feasible and

206 issues directly in live animals would enable minimally invasive surgical techniques for organ repair

207 e evidence on the benefits of endoscopic and minimally invasive surgical therapies for GERD.

208 lasty and/or balloon kyphoplasty (BKP), is a minimally invasive surgical treatment to reduce pain and

209 tside of high-volume centers performing this minimally invasive technique in a nonstandardized fashio

210 Although tape strips show promise as a minimally invasive technique in these common diseases, a

211 iatrogenic injury when using a dual-incision minimally invasive technique to decompress the anterior

212 ion (LCSD) is an effective antifibrillatory, minimally invasive therapy for patients with potentially

213 lance and post-mortem diagnostics, including minimally invasive tissue sampling (MITS), were used.

214 s using all available information, including minimally invasive tissue sampling (MITS).

215 erous lesions that require needle biopsy for minimally invasive tissue sampling and pathological anal

216 edline and Web of Science for RCTs comparing minimally invasive to OPD for adults with benign or mali

217 gery (modified uvulopalatopharyngoplasty and minimally invasive tongue volume reduction; n = 51) or o

218 ernal light delivery, our new opsin offers a minimally invasive tool for manipulating neuronal activi

219 ed using 3D versus 4K display technique at a minimally invasive training Parkour.

220 Such progress toward continuous minimally invasive transdermal analysis of drugs of abus

221 uated its safety and efficacy as a novel and minimally invasive treatment alternative for scar modula

222 roject Closed-loop Molecular Environment for Minimally Invasive Treatment of Patients with Metastatic

223 Minimally invasive treatment of vascular disease demands

224 ased bioprosthetic valve deployment offers a minimally invasive treatment option that eliminates many

225 State of the art minimally invasive treatments and diagnostics of neurolo

226 in the brain without extravasation through a minimally invasive ultrasound interface.

227 the primary predictor was surgical approach (minimally invasive vs open).

228 ed trials are needed to demonstrate whether (minimally invasive) surgery improves functional outcome

229 The method described here is minimally invasive, and for the first time, greatly enha

230 approach might in the future provide a new, minimally invasive, highly specific treatment method for

231 We evaluated the ability of minimally invasive, image-guided vacuum-assisted biopsy

232 this application as it is information-rich, minimally invasive, insensitive to water background and

233 Although AFT is safe, effective, and minimally invasive, only anecdotal evidence exists for r

234 new robot-guided system for semi-automated, minimally invasive, pedicle screw placement.

235 We report a minimally invasive, synaptic transistor-based construct

236 prescribe opioids even in surgeries that are minimally invasive.

237 1 patients received cementless THA through a minimally-invasive anterolateral approach.

238 high volume (>10 resections/yr), 33% offer a minimally-invasive approach, and 50% offer arterial rese

239 lighting the latest progress in the field of minimally-invasive continuous glucose monitoring (CGM) w

240 erosion and may potentially be utilised as a minimally-invasive diagnostic readout for early stage OA

241 are the limitations regarding the use of the minimally-invasive methods and/or biological indicators

242 identified by this review is the paucity of minimally-invasive methods for investigating neurogenesi

243 Nurse researchers have access to many minimally-invasive methods to measure altered biological

244 Studies included minimally-invasive methods to measure the hypothalamic-a

245 estions: What are the characteristics of the minimally-invasive methods used to measure the biologica

246 Remote and minimally-invasive modulation of biological systems with

247 troduce laser cavitation rheology (LCR) as a minimally-invasive optical method to characterize mechan

248 goal of highly stable and reliable real-time minimally-invasive or non-invasive glucose monitoring.

249 ype of laser therapy as a safe and effective minimally-invasive treatment option.

250 We define ECLL's potential role as a minimally-invasive, ultra-low-cost technology for reduci

251 Diabetes minimally mediated the association between PM(2.5) and k

252 649; replication: n = 427) comprising young, minimally medicated patients with clinical high-risk sta

253 rea and squaramide artificial backbones from minimally modified 3'- and 5'-amino oligonucleotides is

254 nd a diastereoselective net arylation of the minimally modified nonsteroidal anti-inflammatory drug (

255 We find that local linear coupling between minimally nonlinear signaling and cytoskeletal systems,

256 d A71915-treated 2-copy and 4-copy mice, but minimally occurred in Rp-treated mice compared with cont

257 ly on the state where reward is obtained but minimally on the preceding choice.

258 ts with FEP (duration of psychosis <2 years, minimally or never treated with antipsychotics) undergoi

259 fic Lden; NO2; and PM2.5, respectively, with minimally overlapping signals.

260 molgus (Macaca fascicularis) macaques with a minimally passaged Brazilian ZIKV isolate and used multi

261 was rapidly and persistently degraded by the minimally passaged HCMV strain Merlin but not the extens

262 tal morphogenesis and organ architecture are minimally perturbed in Jag1 mutants until later stages,

263 hes 2'-alkynyl nitroxide spin-labelling as a minimally perturbing method for probing DNA conformation

264 xides at the 2' position offers a robust and minimally perturbing tool for obtaining such measurement

265 Using F29, we engineered a sensitive, minimally-perturbing fluorescence-resonance-energy-trans

266 for segmentation has the advantage of being minimally phototoxic and leaving all other channels avai

267 smic reticulum were abundant in the soma but minimally present in MFB axons, suggesting that biosynth

268 and specific detection of small molecules in minimally processed biosamples.

269 as investigated on shelf life and quality of minimally processed pomegranate arils during storage at

270 is conducted using freeze-dried or otherwise minimally processed products, yet BRBs are typically con

271 Substitution of high-GI foods with minimally processed, whole, fiber-rich carbohydrates sho

272 less construct GiKIN14a-Deltatail is still a minimally processive motor and moves its center of mass

273 effects on immature neurons, growth factors minimally promote axon regeneration in the adult central

274 occluded Asp act as an integral until which minimally rearranges even as the bulk undergoes extensiv

275 cal DNA sampling, a reduction in effort only minimally reduced costs due to the need for increased la

276 l cells are reported to be glycolytic and to minimally rely on mitochondria for ATP generation.

277 The minimally required metabolic changes required for acetat

278 Thus, it allows power analyses to define minimally required sample sizes.

279 neuropeptides and transcription factors are minimally required to decode the taxonomical hierarchy o

280 Polycomb Repressive Complex 2 (PRC2), which minimally requires two other subunits, EED and SUZ12, fo

281 In contrast, anaerobic microbes were only minimally revived from this oxic sediment.

282 Ninety-six smooth (S) and 96 minimally rough (R) titanium microimplants were used.

283 inclusion of a strong adjuvant that has been minimally studied in clinical settings where it might be

284 ceptors such as NOD-like receptors have been minimally studied.

285 vide additional evidence for asymptomatic or minimally symptomatic EVD.

286 However, its benefits in asymptomatic or minimally symptomatic patients remain unknown.

287 eening chest radiography for asymptomatic or minimally symptomatic patients with COVID-19.

288 icular reverse remodeling in asymptomatic or minimally symptomatic patients.

289 RS-CoV-2) infection in children is typically minimally symptomatic.

290 Using a minimally tied trefoil protein as the framework for unde

291 s was geographically dispersed, contributing minimally to HIV burden in destination locations.

292 te was relatively unreactive and contributed minimally to the generation of ROS.

293 or temporal basal structures that contribute minimally to the scalp electroencephalogram.

294 umerous pediatric cancer cell lines and were minimally toxic to nontumorigenic cells.

295 ns can be carried out at remote sites and by minimally trained personnel, while quantification will t

296 After minimally traumatic tooth extraction, alveolar ridge dim

297 h as the transmission-stage plasmepsins, are minimally understood.

298 In conditions such as minimally-verbal autism, standard assessments of languag

299 ioids (P = 0.39) between patients undergoing minimally versus open colectomy.

300 procedure but enhanced visual outcomes only minimally when compared to conventional cataract surgery