ライフサイエンスコーパス: minor

1 atified by centre and surgery type (major or minor).

2 lications, which were classified as major or minor.

3 bleeding occurred in the first month and was minor.

4 across the Strait of Gibraltar and via Asia Minor.

5 valve culture results per 2-day interval was minor.

6 -O-methyltransferase (7OMT), with relatively minor 6OMT activity and a strong stereospecific preferen

7 elated cirrhosis in opposite directions: the minor A allele in MARC1:rs2642438 decreases risk, wherea

8 abetes in the phase 2 validation cohort, the minor A allele of MARC1:rs2642438 was associated with re

9 -varietal ciders), 2-phenylethanol, and some minor acetate esters (higher in the bi-varietal ciders).

10 Sixteen patients reported minor adverse events.

11 hosphatidylglycerol lipids overall but has a minor affinity for phosphatidylcholine lipids.

12 s every day, but is commonly assumed to be a minor agent of tree mortality in most tropical forests.

13 Each copy of the minor allele (frequency of 4.7%) reduces height by 2.2 c

14 mong 102 patients with baseline samples, the minor allele (T) in NLRC4 rs385076 was independently ass

15 omposite score (meta-analysis effect size of minor allele beta(meta) = -6.04; 95% CI: -8.13 to -3.94;

16 were higher for patients homozygous for the minor allele carrying higher ADA risk (mean: 2,693 pg/ml

17 Although the minor allele frequencies of TMEM40 rs11719526 were gener

18 Minor allele frequencies of two fetal CD46 SNPs were sig

19 ent ethnic groups, BAG3 rs17617337 was rare (minor allele frequencies<0.05) in Asian and African ance

20 genome-wide significance level regardless of minor allele frequencies.

21 o date have mainly analyzed common variants (minor allele frequency > 0.05).

22 The percentage of SNPs with minor allele frequency >0.10 was 95% and 91% in the euch

23 patients carry a very rare missense variant (minor allele frequency < 0.0001) in BRIP1.

24 w BP-associated genomic regions and 87 rare (minor allele frequency <= 0.01) variant BP associations

25 e-wide significant association (rs146350366, minor allele frequency (MAF) 1.2%, P = 3.2 x 10(-8), odd

26 ex single nucleotide polymorphism rs2571244, minor allele frequency = 0.08, P = 2.3 x 10-8).

27 t, LoF mutation in MEPE, p.(Lys70IlefsTer26, minor allele frequency [MAF] = 0.8%), was associated wit

28 BigTop uses the z-axis to display minor allele frequency of each SNP, allowing for the ide

29 requency functional protein-coding variants (minor allele frequency, <=5%) measured by an exome array

30 ndividuals of African ancestry (~10% and ~1% minor allele frequency, respectively, and rare or monomo

31 -to-creatinine ratio (rs527493184 at ZBTB16, minor allele frequency=0.002, P=1.1x10(-8)).

32 omerular filtration rate (rs58720902 at AQR, minor allele frequency=0.01, P=1.6x10(-8)) or urine albu

33 0% false discovery rate (FDR) threshold, the minor allele of rs10508884, which is situated in an intr

34 B7C (P(inter) = 1.83 x 10(-7)), in which the minor allele of rs1944572 confers increased risk for AD

35 tem experiments, we found that inserting the minor allele of rs9315202 in a human kidney cell line HK

36 non-local alternative model for differential minor allele rates at each marker, in which the null and

37 Introduction of this minor allele SNP by genome editing confirmed its functio

38 ly associated single-nucleotide polymorphism minor allele with increased BCL2 gene and protein expres

39 p < 1 x 10-5 for patients homozygous for the minor allele) and was chosen for validation through a CX

40 outputs or with a minimum of 5 isolates with minor allele.

41 The minor alleles of these SNPs were associated with signifi

42 ns-the major shrimp allergen Pen m 1 and the minor allergens Der p 10 (dust mite), Bla g 7 (cockroach

43 Furthermore, we observed minor alterations in protein levels, 2 hours after drug

44 indicated that many parameters, most notably minor amounts of ADP generated during autophosphorylatio

45 of Chl f, red-shifted phycobiliproteins and minor amounts of Chl d via far-red light photoacclimatio

46 However, we find that minor amounts of O are present in the CO-poisoned layer

47 Fourteen minor and 21 major complications occurred in 29 of the 5

48 ast, changes in the microbial community were minor and transient, and very few differences were obser

49 erall community structure and diversity were minor and varied among fields and years.

50 Unexpectedly, only minor antigen-mismatched grafts were rejected at the sam

51 experimental system in which MHC-matched but minor antigen-mismatched tissue (skin) grafts were trans

52 nor antibodies were not detected only in the minor antigen-mismatched transplantation.

53 Albeit reduced over time, MI and even minor BARC 2 bleeding significantly influenced mortality

54 Reprogramming of Majors upregulates Minor-biased genes and downregulates Major-biased genes,

55 the limit of detection of uPIXE, suggesting minor biological utilisation in this environmental setti

56 the low-molecular-weight heparin group, and minor bleeding events in 478 (12.1%) of 3945 patients wi

57 ant nonmajor bleeding events, and 37 (18.2%) minor bleeding events.

58 Thrombolysis in Myocardial Infarction) major/minor bleeding with time-dependent c-indices.

59 for major bleeding, and 1.34 (1.19-1.51) for minor bleeding.

60 an PMEL17, we tested the hypothesis that the minor, but more aggregation-prone, sRPT facilitates amyl

61 MARC1:rs2642438 decreases risk, whereas the minor C allele in HNRNPUL1:rs15052 increases risk.

62 odds ratio, 0.76; P=.0027); conversely, the minor C allele of HNRNPUL1:rs15052 was associated with a

63 plant cell wall polysaccharides, more so of minor cell wall components that are especially challengi

64 nly consisted of type I collagen with only a minor cellular component (especially fibroblasts/myofibr

65 ous varieties of this recently re-discovered minor cereal.

66 egion shuffling identified a major CH3 and a minor CH2 contribution, which was further mapped to disc

67 icing of few genes, which may be viewed as a minor change in the cells' whole transcriptome, can dete

68 scle acetylcarnitine metabolism, and induced minor changes in body composition and sleeping metabolic

69 d its mammalian homologs, MLL3/4, cause only minor changes in gene expression compared with whole-gen

70 d screws were culture-positive and displayed minor changes in peri-implant bone, characteristic of su

71 However, statistical analyses revealed minor changes in the pioneer bacteria (class level) and

72 Surprisingly, we detected only minor changes in the translational profiles of neurons.

73 ggs from larp6b single mutant females showed minor chorion defects, but chorions from eggs laid by la

74 pulp procyanidins were presented with only a minor class of oxidized procyanidins.

75 (19.9%), of which 176 patients (81.5%) were minor (Clavien-Dindo class I and II).

76 novalent cations resulted in aggregation and minor coalescence, while divalent cations resulted in ex

77 Adenovirus minor coat protein VI contains a membrane-disrupting pep

78 ler than generally expected, and potentially minor compared with those caused by sensorineural hearin

79 or with greater AN loss but are potentially minor compared with those caused by SNHL.SIGNIFICANCE ST

80 detected, but six patients (13.9%) developed minor complications after MWA.

81 Minor complications included cyst formation, infection,

82 A series of minor complications was collected, no case of which requ

83 The only risk factor for minor complications was previous radiation therapy (AOR,

84 The most common minor complications, or those not requiring intervention

85 verse events related to treatment, major and minor complications.

86 component of TLG, whereas SUL(average) was a minor component and was essentially constant.

87 ied as sulfonimide dimers that were either a minor component of the AFFF or were formed via metabolis

88 ss of ~26 kDa (major component) and ~24 kDa (minor component).

89 nd recalcitrant compounds that are generally minor components of crude oil (~0.1-15.0 wt %) but domin

90 have been found for the first time among the minor components of these lipids.

91 3.6 mg/kg) and safrole (0.20-3.0 mg/kg) were minor components.

92 In addition, our results stress how minor compounds in complex mixtures can produce a meanin

93 ctures that are sufficient to characterize a minor conformational state of the C-terminal region of D

94 Some minor constituents of honey samples were determined thro

95 raphic origin on the content of the analyzed minor constituents of honey, particularly phenolic compo

96 mographic characteristics and obesity with a minor contribution of chronic comorbid conditions.

97 We observed that N- and O-glycans had only minor contribution to Spike-ACE2 binding.

98 mate 3-phosphate synthase (EPSPS) gene, with minor contributions from EPSPS gene duplication/overexpr

99 interactions with host-derived N-glycans and minor contributions of antibody somatic hypermutations t

100 though the latter two isoforms showed rather minor contributions to total Cho kinase activity in both

101 ation followed by canned tuna, but fish is a minor contributor to exposure.

102 In conclusion, S. minor could be a source of natural bioactive compounds,

103 o increase crop species diversity, currently minor crops would have to increase in area at the expens

104 racterization and bioactive properties of S. minor cultivated under different fertilization rates (co

105 depletion of ZC3H5 in vivo caused only very minor decreases in a few targets, marked increases in th

106 In CRVO patients, even minor delays between symptom onset and first injection l

107 he lattice correspondence of the twin with a minor deviation from the ideal orientation.

108 With minor deviations, omega-3 fatty acid content and lipid c

109 However, there was only a minor difference in chloroplast morphology, likely becau

110 in the IVB and control groups, except for a minor difference in motor performance.

111 We find only minor differences between the isotopic ecology of both t

112 aradigms in freely-moving mice that revealed minor differences following chronic head-fixation.

113 ctivity persisted for hours after pMCAo with minor differences from baseline, spatiotemporal analyses

114 There are minor differences in complexity of patients undergoing c

115 higher levels of IFN-beta despite relatively minor differences in replication capacity.

116 Minor differences in the amino acid sequences of the ops

117 es with identical constant portions but with minor differences in their V regions have been demonstra

118 of all three viruses are similar, with only minor differences observed in the previously described s

119 ecision, with the exception of DDA showing a minor disadvantage (on average 19.8% and 26.8% fewer fea

120 F220C mice exhibited minor disruptions of photoreceptor outer segment dimensi

121 Even minor disruptions to these processes can result in delet

122 However, only minor ecological impacts of invader abundance and phenot

123 affected stability of anthocyanins, but had minor effect on ascorbic acid, which declined rapidly in

124 owed that the temperature range tested had a minor effect on bound-forms hydrolysis, being both free

125 abundance in the water (~70%) but had only a minor effect on the bacterial community composition in t

126 ture distribution, while sheeting only had a minor effect.

127 a nutritional role in development with only minor effects in the adult.

128 in biotherapeutic formulations and that only minor effects in tryptophan fluorescence peak tailing ar

129 While ER mutations exhibited minor effects on ER genomic binding, with the exception

130 27 reduces insulin mRNA in vivo but has only minor effects on glucose tolerance.

131 inearities had statistically significant but minor effects on reconstruction.

132 ity functional theory (DFT) showed water has minor effects on the reaction thermodynamics, primarily

133 se events from treatment were infrequent and minor (eg, candidiasis) but were slightly more common wi

134 Our analysis reveals that relatively minor evolutionary changes in morphology and neural cont

135 With some minor exceptions, the method displayed good linearity (R

136 rameter depended mostly on MTA and only to a minor extent on canopy height and their interaction.

137 ved in primary long chain alcohols and, to a minor extent, in long-chain wax esters.

138 Endoplasmic reticulum omega-oxidation, a minor fatty acid degradation pathway known to be stimula

139 ith patients not receiving chloroquine found minor fever resolution and virologic clearance benefits

140 cal material including the microbiota, and a minor form derived from the distal colon, which adheres

141 itted in the WWTP effluents, although only a minor fraction (<1%) of the total processed API quantity

142 is conducted with added acetaldehyde, only a minor fraction (up to 36%) of 1-propanol is from this pa

143 clines of up to ~70%, thus offsetting only a minor fraction of agricultural losses.

144 trations in foam, indicating that PFAS are a minor fraction of DOC and that DOC likely plays a centra

145 d autoimmunity, with Brg1 re-expression in a minor fraction of Treg cells sufficient for the resoluti

146 changes, our model results support only very minor fractions (1%) of the halogen inventory reaching t

147 lyzed for gamma-linolenic acid-rich oils and minor functional compounds.

148 transcriptome of these cells while inducing minor gene expression changes in TSC2 add-back cells.

149 enotype, while South American clade IV was a minor genotype.

150 Minor GPI processing was also observed, consistent with

151 grade 3 or 4, severe or life-threatening) or minor (grade 1 or 2, mild or moderate) according to Comm

152 d that a loop within Orc2 inserts into a DNA minor groove and an alpha-helix within Orc4 inserts into

153 eta decreased ~380-fold when Asn279-mediated minor groove contact to dGTP was abolished.

154 etry, which was stabilized by Gln38-mediated minor groove contacts to oxoA:dGTP.

155 TFBS entry now include 13 shape features and minor groove electrostatic potential for standard DNA an

156 A-mediated mutagenesis is greatly induced by minor groove interactions.

157 erefore preventing HMGA2 from binding to the minor groove of AT-rich DNA sequences.

158 be discovered that selectively binds to the minor groove of DNA and is actively used as a scaffold f

159 erizing a protein loop that intercalates the minor groove of the DNA (termed the intercalating loop).

160 Here, we constructed and applied Minor Groove Width (MGW) as a prioritization metric.

161 core motif, with most contacts formed in the minor groove, differs from previously observed protein-D

162 Crick pairs as long blocks and highlight the minor-groove edges.

163 alkyl-2'-deoxyguanosine (O (6)-alkyl-dG) and minor-groove N (2)-alkyl-dG lesions in human cells, wher

164 ch other in an X-shape to form two nonplanar minor-groove-aligned G.C.G.C tetrads.

165 Minor histocompatibility antigen (MiHA)-specific T cells

166 ively mediated by T cells that recognize the minor histocompatibility antigen H60.

167 an fluorescence intensity [aMFI] >= 1000), a minor histocompatibility antigen, associated with graft

168 We demonstrated that HIFalpha played a minor, if any, role in regulating canonical Wnt signalin

169 of miRNA-driven transcript degradation has a minor impact on miRNA-mRNA correlations, which are, in o

170 k1a-dependent Munc18-1 phosphorylation has a minor impact on synaptic transmission, only after intens

171 e, mechanical/physical processing had only a minor impact.

172 e of LARS was 82.6% (n = 109/132), which was minor in 26/132 (19.7%) and major in 83/132 (62.9%).

173 e greatest neuronal density in layer Cm, the minor in the top sublayer of layer A).

174 assland, annual seepage under the forest was minor in years with an average rainfall.

175 time, as well as contrast utilization, and a minor increase in procedure duration compared with tradi

176 idence in 5 to 9-year-old children, and have minor indirect benefits.

177 Minor InSTI resistance mutations had no impact in this l

178 identified risk factors, including baseline minor InSTI resistance mutations, for treatment failure

179 t of the integrase, we studied the impact of minor integrase resistance mutations.

180 that limb size is reduced owing to elevated minor intron retention in minor intron-containing genes

181 ssion is controlled through an autoregulated minor intron, tightly correlating Srsf10 with minor spli

182 owing to elevated minor intron retention in minor intron-containing genes that regulate cell cycle.

183 of age, with transient ischaemic attack and minor ischaemic stroke occurring between March 1, 2011,

184 permitted identification of major, and some minor, isomeric contributors that are unresolved using c

185 as observed in 25 cells, while two different minor karyotypes were observed in the other cells.

186 intramural hematoma, mucosal laceration) and minor lesions (petechiae, ecchymosis).

187 )CD11b(+)Ly6c(low)Ly6g(high) cells, but only minor leukocyte infiltration into acutely ischemic-reper

188 Considering the minor level of performance differences between the algor

189 roups of 3 may be the best for reducing even minor levels of aggression (i.e. wounding).

190 such as intravitreal injections (23.1%) and minor lid procedures (38.5%).

191 e characterization of not only main but also minor lipid components of both corn and tortilla.

192 d in 50% ethanol solution and dried obtained minor losses of total phenolics, total carotenoids, and

193 rimary outcomes were all bleeding (including minor, major, and life-threatening or disabling bleeding

194 All minor, major, and overall complications were insignifica

195 Plasmodium malariae is considered a minor malaria parasite, although its global disease burd

196 Because these antibodies show only minor, manageable adverse effects in humans, they offer

197 superior separation capacity to fractionate minor metabolites compared to HPLC.

198 Major and minor metabolomic components of Apulian Coratina EVOO ob

199 tly replaced by orthopyroxene, troilite, and minor metal.

200 nsitive to the structure of the ligand, with minor modifications inhibiting its formation.

201 iant forms, some of which may differ by only minor modifications of a single amino acid.

202 rocedure esophagogastroduodenoscopy revealed minor mucosal thermal injury in 2 of 36 RF/PF and 0 of 2

203 ed levels of serum creatine kinase but no or minor muscle weakness.

204 variant exists in a major native state, two minor native-like states, and two locally unfolded state

205 was safety for oral administration, since a minor number of dead cells were found in red color under

206 timescale as in Uruguay, and are present in minor numbers in distant countries.

207 ersus 8%, respectively; p=0.001); most were 'minor' (nurse prescribers=489, 56%; patient group direct

208 combined with baker's yeast production (with minor nutrient supplementation), is also proposed.

209 ge volume effusive eruptions with relatively minor observed precursory signals are at odds with widel

210 ities, with fever, headache, and muscle ache minor or absent.

211 ents are likely common occurrences following minor or major corneal trauma.

212 +) reduction of nitrogen to hydrazine with a minor overpotential of ~300 mV.

213 The mass-independent minor oxygen isotope compositions (Delta'(17)O) of atmos

214 ndian strains as major (98.1%, KR140086) and minor parents (99.8%, KT860064).

215 ribosome collisions initiating RQC, another minor pathway contributed to their monoubiquitination.

216 dration (major pathway) and decarbonylation (minor pathway) to liberate toxic HCN and CO, respectivel

217 This minor peptidic difference results in the induction of tw

218 Besides oleuropein, other minor phenolic compounds were characterized in the extra

219 It suggests that minor phylogenetic groups in the community might be resp

220 demonstrate that the PilY1 protein and four minor pilins, which are widely conserved in T4aP systems

221 wn to be vital for NMR structure analysis of minor polysaccharide components of plant cell walls that

222 to the major polysaccharide components, two minor polysaccharides, namely, <5% 3-linked arabinoxylan

223 c-Kit(+) ICs are a minor population of ICs in murine renal pelvis.

224 A minor population of macrophage-tropic (M-tropic) viruses

225 'Cancer stem cell theory' purports that a minor population of stem cells among the heterogeneous p

226 olymorphisms (SNPs) and constant turnover of minor population variants, each rising and falling over

227 minantly neutral, and the Q/H segments adopt minor populations of helical structure, show decreased m

228 Using these tools, we find a minor presence of PI in membranes of the ER, as well as

229 .5%) and assisting in ophthalmic surgery and minor procedures (65.0%).

230 100 degrees C is N(2) with N(2) O being the minor product.

231 ta-1 loci, we found additional but different minor QTLs in the 0 and 14% alcohol environments.

232 em does not require auxiliary beams and only minor reconfiguration for different wavelengths.

233 This study defines the subdominant PfCSP minor repeats as neutralizing epitopes, identifies an in

234 XP-knockout replicons have only a minor replication defect, demonstrating the role of XP a

235 Minor resistance mutations were found at baseline in 104

236 d many patients with anosmia show no or only minor respiratory symptoms(1).

237 igator-assessed overall response (at least a minor response) according to the 6th International Works

238 Neuroscience research is undergoing a minor revolution.

239 es Society of America (IDSA), women played a minor role as IDSA leaders, awards recipients, and prese

240 cies composition and litter quality played a minor role compared to N-driven reductions in soil pH an

241 are critical for complex II, but have only a minor role for complex I.

242 A minor role for retromer in Snc1 recycling can also be ob

243 We also show that the Balbiani body has a minor role in mtDNA selective inheritance by supplying h

244 Our experimental findings indicate possibly minor role of the change in pai-electron conjugation len

245 tion technique for larger vessels may play a minor role, and hemostatic agents could be of higher imp

246 nbiased transcriptome profiling data sets of minor salivary gland biopsies from controls and Sjogren'

247 ated CpG flanking sequence bias in major and minor satellite repeats that is consistent with DNMT3A a

248 and Miwi slicer-deficient mutants, major and minor satellite RNAs from centromeric and pericentromeri

249 ea and vomiting, and endoscopy revealed only minor self-limiting ulcers in 5 patients.

250 ss or scapular girdle weakness, 6.7% display minor signs such as winged scapula or hyperCKemia, witho

251 t causes an array of infections ranging from minor skin infections to more serious infections, includ

252 hybridization and that selection against the minor species genome might be similar across experimenta

253 The existence of this minor species is the result of the LLPS occurring concom

254 inor intron, tightly correlating Srsf10 with minor spliceosome abundance across different tissues and

255 d animals is linked to positive selection in minor spliceosome components.

256 Disruption of the minor spliceosome due to mutations in RNU4ATAC is linked

257 Here, we disrupt minor spliceosome function in the developing mouse limb

258 Overall, we show that the minor spliceosome is required for limb development via s

259 tensive crosstalk and a global impact of the minor spliceosome on major intron splicing.

260 course of SSc-ILD is variable, ranging from minor, stable disease to a progressive course, whereas a

261 as contributing to understanding the role of minor states in biology and molecular evolution.

262 Poor aqueous solubility of some minor steviol glycosides (SGs) has prevented their poten

263 ctiveness of CT angiography in patients with minor stroke (National Institutes of Health Stroke Scale

264 essel occlusion (LVO) in patients with acute minor stroke (NIHSS score <=6).

265 ascular Study (2011-2020) with suspected TIA/minor stroke and non-invasive angiography were included.

266 Background Minor stroke is common and may represent up to two-third

267 n with CT angiography in patients with acute minor stroke is cost-effective and associated with impro

268 patients with transient ischaemic attack and minor stroke on intensive medical management.

269 gnosis of UIA in patients with suspected TIA/minor stroke.

270 as greater than 0.16% in patients with acute minor stroke.

271 fluorine incorporation into SH3 causes only minor structural changes to both the free and bound stat

272 ally, a remarkable regiochemical switch upon minor structural modification of a diketal is also analy

273 ptide derived from the BK polyomavirus (BKV) minor structural proteins VP2/3 that is a potent inhibit

274 forming an integrated evolutionary analysis, minor subclones are identified in 9 patients that expand

275 the SDBC and allows the retention of several minor subunits.

276 nts aged 18 to 64 years undergoing major and minor surgery between 2008 and 2015.

277 y or less than 50 x 10(9) cells per L before minor surgery.

278 patient surgery and FTR, ever after common, 'minor' surgical procedures.

279 Minor to no differences were observed for levels of anti

280 settings of mass displacement, unaccompanied minors (UAMs) are recognized as a vulnerable group and c

281 on and nitrosation processes was found to be minor under our experimental conditions.

282 th frequent HSV DNA shedding, with mixing of minor variants between her tissues.

283 The minor variants within a patient may contribute to the ov

284 To investigate the effects of these minor variants, blood samples from patients with acute E

285 ere slightly changed and FTIR spectra showed minor variation in peak intensities of oils from differe

286 een species, although there were a number of minor variations across a range of nuclei in the density

287 Although there were minor variations in characteristics of iNTS in different

288 epresented many different parameters through minor variations in firing rates, LA cells coded fewer t

289 n (2.47 +/- 1.84 versus 1.03 +/- 1.48 mm; no/minor versus major exposure, P = 0.051) and PD reduction

290 of LARS and secondary outcome was severity (minor versus major).

291 all wine quality and sensory parameters were minor when adjusting musts within the limit of 13.5 degr

292 mild drought), reductions in midday Psi were minor while predawn Psi continued to decline during phas

293 ween the methods in the left lung lobes were minor, with a mean difference of -0.4 +/- 4.4 (P > 0.05)

294 tural mechanism differentiating "Major" and "Minor" worker ants.

295 rogrammed to forage for food analogously to "Minor" workers.

296 affinity paralog of 4CL1 typically with only minor xylem expression or activity.

297 depleting cohesin in donor cells facilitates minor ZGA and SCNT.

298 Notably, inhibition of minor ZGA impairs the Pol II pre-configuration and embry

299 and 'production' during the transition from minor ZGA to major ZGA.

300 Unexpectedly, we found cohesin represses minor zygotic genome activation (ZGA) genes (2-cell-spec