ライフサイエンスコーパス: mitochondrial matrix

1 d by a coiled-coil motif protruding into the mitochondrial matrix.

2 into mitochondria, where it localizes to the mitochondrial matrix.

3 manner, suggesting a role for PB2 within the mitochondrial matrix.

4 singly complex mtHsp70: JDP network in their mitochondrial matrix.

5 bilization and translocation of p53 into the mitochondrial matrix.

6 hanisms localized across the membrane in the mitochondrial matrix.

7 rate that DAP3 specifically localizes in the mitochondrial matrix.

8 rane (MAM) prior to its translocation to the mitochondrial matrix.

9 e same side of the membrane, probably in the mitochondrial matrix.

10 ic localization and was also targeted to the mitochondrial matrix.

11 dly between the cytosol, plastid stroma, and mitochondrial matrix.

12 everal folate-interconverting enzymes in the mitochondrial matrix.

13 s (oscillations) chronically loaded into the mitochondrial matrix.

14 DP from the cytosol and exports ATP from the mitochondrial matrix.

15 is crucial for the import of proteins to the mitochondrial matrix.

16 raps folates in the cytosol, but also in the mitochondrial matrix.

17 ular process of transient contraction of the mitochondrial matrix.

18 trix state, in which it accepts ATP from the mitochondrial matrix.

19 outer mitochondrial membrane, but not in the mitochondrial matrix.

20 ost likely due to flux of K(+) ions into the mitochondrial matrix.

21 rations of reactive acyl-CoAs present in the mitochondrial matrix.

22 port of a subpopulation of proteins into the mitochondrial matrix.

23 litates transfer of this hybrid RNA into the mitochondrial matrix.

24 ioxidant enzyme localized exclusively in the mitochondrial matrix.

25 respectively; the opposite occurs within the mitochondrial matrix.

26 ry defect and aggregation of proteins in the mitochondrial matrix.

27 tDNA, proving the presence of mtDNMT1 in the mitochondrial matrix.

28 l source of the second messenger cAMP in the mitochondrial matrix.

29 ding to increased Ca(2+) accumulation in the mitochondrial matrix.

30 the import of nuclear-encoded RNAs into the mitochondrial matrix.

31 Pos5p is the only known NADH kinase in the mitochondrial matrix.

32 nt of low molecular mass exists in the yeast mitochondrial matrix.

33 n readily transduce a protein cargo into the mitochondrial matrix.

34 of a TAT-containing protein to move into the mitochondrial matrix.

35 essing a redox-sensitive GFP targeted to the mitochondrial matrix.

36 the inner mitochondrial membrane facing the mitochondrial matrix.

37 space, and Grx2, localized primarily to the mitochondrial matrix.

38 ubstrate-binding site is accessible from the mitochondrial matrix.

39 h a protein that regulates the volume of the mitochondrial matrix.

40 a trap door for the flux of folates into the mitochondrial matrix.

41 nal tubule is an extensive remodeling of the mitochondrial matrix.

42 se postulated to function in the cytosol and mitochondrial matrix.

43 ridges that seal the pathway to and from the mitochondrial matrix.

44 more reducing thiol redox environment in the mitochondrial matrix.

45 duct), a prolyl isomerase located within the mitochondrial matrix.

46 that lactate is not directly oxidized in the mitochondrial matrix.

47 embrane space, SOD1 is also localized in the mitochondrial matrix.

48 multicopy closed circular genome within the mitochondrial matrix.

49 americ chaperonin that folds proteins in the mitochondrial matrix.

50 e cytosol, subplasma membrane domain, or the mitochondrial matrix.

51 eins shared the same import pathway into the mitochondrial matrix.

52 nsporting pyruvate from the cytosol into the mitochondrial matrix.

53 c LD-mitochondrial interface, but not to the mitochondrial matrix.

54 TP), which is subsequently exported from the mitochondrial matrix.

55 alcium from the endoplasmic reticulum to the mitochondrial matrix.

56 us impedes the accumulation of Gboxin in the mitochondrial matrix.

57 r the localization of small molecules to the mitochondrial matrix.

58 of our method by examining the well-studied mitochondrial matrix.

59 ae cluster, which enclosed the lower density mitochondrial matrix.

60 t proteins localized either in cytosol or in mitochondrial matrix.

61 COX biogenesis is a labile pool found in the mitochondrial matrix.

62 sorted to the inner membrane, as well as the mitochondrial matrix.

63 EGSH were observed in the cytoplasm and the mitochondrial matrix.

64 following mitochondrial import, resulting in mitochondrial matrix accumulation of mature Hep27.

65 ial pyruvate uptake that can be explained by mitochondrial matrix acidification.

66 biosensor roGFP2 was rapidly oxidized in the mitochondrial matrix after injury, and WldS expression p

67 The arginases are both localized to the mitochondrial matrix and closely related.

68 ta-induced ROS could be detected in both the mitochondrial matrix and cytosol.

69 he cytoplasm and, to a lesser degree, in the mitochondrial matrix and ER lumen.

70 carriers import adenine nucleotides into the mitochondrial matrix and export phosphate to the cytosol

71 U isoform (mitoCLU) that is localized to the mitochondrial matrix and expressed in both rodent and hu

72 oxide dismutase, catalase-are distributed in mitochondrial matrix and extra-matrix compartments, and

73 unctional protein localized primarily in the mitochondrial matrix and has roles in inflammation and i

74 an DHFRL1, SHMT2, and TYMS were localized to mitochondrial matrix and inner membrane, confirming the

75 ave identified an endogenous pool of DJ-1 in mitochondrial matrix and inter-membrane space.

76 Here, we show that SIRT5 localizes in the mitochondrial matrix and interacts with carbamoyl phosph

77 t, human recombinant NMNAT3 localizes to the mitochondrial matrix and is able to catalyze NAD(+) bios

78 atalyzes the oxidation of persulfides in the mitochondrial matrix and is essential for early embryo d

79 iderably more oxidizing than the cytosol and mitochondrial matrix and is not directly influenced by e

80 RESEARCH DESIGN AND Mitochondrial matrix and membrane fractions were generat

81 in is nuclear-encoded, it is targeted to the mitochondrial matrix and necessary for proper regulation

82 rted to exert biological effects in both the mitochondrial matrix and outer mitochondrial membrane (O

83 inal microvasculature region revealed normal mitochondrial matrix and packed lamellar cristae.

84 Mechanistically, AMPK localizes in the mitochondrial matrix and phosphorylates the catalytic al

85 to insufficient levels of FXN protein in the mitochondrial matrix and probably other cellular compart

86 ursor polypeptide that is transported to the mitochondrial matrix and processed to at least two forms

87 in metabolism, whereas Sirt3-5 reside in the mitochondrial matrix and regulate various enzymes involv

88 We found that PB2 is imported into the mitochondrial matrix and showed that amino acid residue

89 ession increases the electron density of the mitochondrial matrix and swelling of cristae.

90 ransport of reducing equivalents between the mitochondrial matrix and the cytoplasm relies on shuttle

91 des of the mitochondrial inner membrane: the mitochondrial matrix and the extramitochondrial space.

92 brane isoform with the C-terminus facing the mitochondrial matrix and the N-terminus facing the inter

93 to oxidative stress, p53 accumulates in the mitochondrial matrix and triggers mitochondrial permeabi

94 on cytoplasmic ribosomes, imported into the mitochondrial matrix, and assembled into the complex wit

95 )O(2) emission, less oxidative damage to the mitochondrial matrix, and increased tolerance to the Ca(

96 Acots in the mitochondrial matrix are poised to mitigate beta-oxidati

97 iciency, protein folding environments of the mitochondrial matrix are prone to dysregulation, prompti

98 ologic pH and acyl-CoA concentrations of the mitochondrial matrix are sufficient to cause dose- and t

99 st proteins that are to be imported into the mitochondrial matrix are synthesized as precursors, each

100 Proteins destined for the mitochondrial matrix are targeted to the inner membrane

101 e cytochrome c oxidase is synthesized in the mitochondrial matrix as a precursor whose leader peptide

102 ynamically regulated by Ca(2+) levels in the mitochondrial matrix as well as by cytosolic ADP.

103 The mitochondrial matrix ATPase associated with diverse cell

104 edict targeting of the mature peptide to the mitochondrial matrix, based on an N-terminal, amphipathi

105 ol with the energy-providing pathways in the mitochondrial matrix becomes critical for deepening our

106 cells is organized into nucleoids within the mitochondrial matrix, but how mtDNA nucleoids are formed

107 link biochemical pathways in the cytosol and mitochondrial matrix by transporting substrates across t

108 a(2+) efflux resulting in elevated levels of mitochondrial matrix Ca(2+) and enhanced activation of C

109 shRNA resulted in a constitutive increase in mitochondrial matrix Ca(2+) and reduced nicotinamide ade

110 Mitochondrial matrix Ca(2+) concentration is maintained

111 ate that SLC25A23 plays an important role in mitochondrial matrix Ca(2+) influx.

112 also known as regulators of cell death, and mitochondrial matrix Ca(2+) is a key modulator of both A

113 Upregulation of MCUb limits mitochondrial matrix Ca(2+) uptake and impairs mitochond

114 hypothesized that cytosolic Ca(2+), but not mitochondrial matrix Ca(2+), may adapt OXPHOS to workloa

115 ism of modulating Ca(2+) entry that involves mitochondrial matrix Ca(2+).

116 l motility in axons is actively regulated by mitochondrial matrix Ca(2+).

117 alcium imaging in rhod2-loaded cRHM revealed mitochondrial matrix [Ca(2+)] ([Ca(2+)](m)) responses to

118 xygen species-producing stimuli, or elevated mitochondrial matrix calcium opens the channel, which is

119 rial response independent of Drp1: a rise in mitochondrial matrix calcium through the mitochondrial c

120 we demonstrate that crs encodes a conserved mitochondrial matrix chaperone HSPA9B containing a glyci

121 9, and A1210477), along with the established mitochondrial matrix chaperone inhibitor gamitrinib-TPP.

122 tack, which is selectively controlled by the mitochondrial matrix citrate levels.

123 nce at very high concentrations in the liver mitochondrial matrix) co-evolved to provide buffering ag

124 and Na+ concentrations in the myoplasmic and mitochondrial matrix compartments.

125 p120 DBC-1, caused mitochondrial clustering, mitochondrial matrix condensation, and sensitized cells

126 dicted to be higher than cMDH activity under mitochondrial matrix conditions while the cMDH activity

127 A mitochondrial matrix copper ligand (CuL) complex, conser

128 mers for carrying bioactive molecules to the mitochondrial matrix could be of enormous potential bene

129 Ca(2)(+) accumulation in the mitochondrial matrix dissipates membrane potential (Delt

130 -481), which is selectively localized in the mitochondrial matrix, enhanced organelle fusion and prom

131 GDH is a mitochondrial matrix enzyme that catalyzes the oxidative

132 Acetylcarnitine is produced by the mitochondrial matrix enzyme, carnitine acetyltransferase

133 However, specific liver mitochondrial matrix enzymes and the mitochondrial repai

134 ice variants (MOCS1A) either localize to the mitochondrial matrix (exon 1a) or remain cytosolic (exon

135 nnel which, by tuning Ca(2+) influx into the mitochondrial matrix, finely regulates metabolic energy

136 sponsible for the oxidation of at least nine mitochondrial matrix flavoprotein dehydrogenases.

137 rial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP synthesis, and ATP out to f

138 myces cerevisiae must import copper into the mitochondrial matrix for eventual assembly of cytochrome

139 the import of protoporphyrinogen IX into the mitochondrial matrix for heme synthesis and subsequent h

140 rium supplies the glycolytic products to the mitochondrial matrix for OXPHOS.

141 slocation of long-chain fatty-acids into the mitochondrial matrix for subsequent beta-oxidation, and

142 the trypanothione redox couple and that the mitochondrial matrix harbors a trypanothione system.

143 resent study, the presence of NDUFAF7 in the mitochondrial matrix has been confirmed, and it has been

144 mplex (MCUC) mediating Ca(2+)uptake into the mitochondrial matrix have been identified in mammals, in

145 t protein, and Aim32, its counterpart in the mitochondrial matrix, have a C-terminal thioredoxin-like

146 h) and more moderate induction of mRNAs for mitochondrial matrix HSP60 and the ER lumen HERP, GRP78,

147 follow different translocation routes before mitochondrial matrix import for cPMP biosynthesis involv

148 ell fractionation experiments displayed that mitochondrial matrix import was facilitated via an inter

149 icated that NT-PGC-1alpha was located in the mitochondrial matrix in brown adipocytes.

150 alterations of EGSH in the cytoplasm and the mitochondrial matrix in cardiac myocytes and can be expl

151 ical studies indicate a central role for the mitochondrial matrix in cellular copper metabolism.

152 Lon is the major protease in the mitochondrial matrix in eukaryotes, and is well conserve

153 ClpXP is the major protease in the mitochondrial matrix in eukaryotes, and is well conserve

154 e conclusively that calcium buffering in the mitochondrial matrix in live cells occurs by phase separ

155 endent protease and chaperone located in the mitochondrial matrix in plants.

156 by which the influx of unfolded p53 into the mitochondrial matrix in response to oxidative stress ind

157 ergetics by Ca(2+) signal propagation to the mitochondrial matrix includes local Ca(2+) delivery from

158 ch to identify 495 proteins within the human mitochondrial matrix, including 31 not previously linked

159 mitochondrial inner membrane space into the mitochondrial matrix independent of ATP synthase, uncoup

160 drial- and nuclear-encoded proteins from the mitochondrial matrix into the inner membrane.

161 pid and carbohydrate homeostasis by altering mitochondrial matrix iron metabolism.

162 Calcium (Ca(2+)) uptake into the mitochondrial matrix is critically important to cellular

163 demonstrate that the phosphoproteome of the mitochondrial matrix is extensive and dynamic.

164 hese two findings indicate that although the mitochondrial matrix is fully buffer-capable under quies

165 eleased via ryanodine receptors (RyR) to the mitochondrial matrix is locally supported by high [Ca(2+

166 This suggests that mutant SOD1 in the brain mitochondrial matrix is misfolded and prone to aggregati

167 LDH in the mitochondrial matrix is not compatible with the cytoplas

168 se to unfolded and misfolded proteins in the mitochondrial matrix is poorly understood.

169 Whereas folding of proteins in the mitochondrial matrix is supported by members of several

170 d total concentration of calcium ions in the mitochondrial matrix, leading to disruption of the inner

171 is difficult to reconcile with the presumed mitochondrial matrix localization for endogenous PNPase,

172 underwent proteolytic cleavage resulting in mitochondrial matrix localization of the MOCS1B domain.

173 ycle re-stimulation, which yielded increased mitochondrial matrix-localized ATP via substrate-level p

174 ne proteins which probably use copper from a mitochondrial matrix-localized pool.

175 e dismutase (MnSOD) is a nuclear encoded and mitochondrial matrix-localized redox enzyme that is know

176 Accumulation of Ca(2+) into the mitochondrial matrix may activate the mitochondrial chap

177 ation by ONOO- are discussed in terms of the mitochondrial matrix metabolic and thiol redox state.

178 s expressed in the cytosol (Cyto-RoGFP), the mitochondrial matrix (Mito-RoGFP), or the mitochondrial

179 First, the major redox couples in the mitochondrial matrix (NAD, NADP, thioredoxin, glutathion

180 y of subcellular compartments, including the mitochondrial matrix, nucleus, cytosol, and endoplasmic

181 ese include a strong association between the mitochondrial matrix octapeptidase Oct1p and coenzyme Q

182 d for protein maturation and turnover in the mitochondrial matrix of diverse species.

183 We found that MATalpha1 is present in the mitochondrial matrix of hepatocytes using immunogold ele

184 ox potential (EGSH) in the cytoplasm and the mitochondrial matrix of isolated cardiac myocytes and in

185 for assessing changes in H(2)O(2) within the mitochondrial matrix of living Drosophila.

186 sembly of iron-sulfur clusters occurs in the mitochondrial matrix of mammalian cells, but cytosolic i

187 Here we report that CREB is present in the mitochondrial matrix of neurons and that it binds direct

188 atory subunits and CREB are localized to the mitochondrial matrix of neurons.

189 wing two categories: (1) mistargeting to the mitochondrial matrix or (2) correct localization associa

190 nfinement using tiny enclosures, such as the mitochondrial matrix or chloroplast stroma, to concentra

191 d the substrate or nucleotide from the inner mitochondrial matrix or membrane.

192 tically encoded Ca2+ sensors targeted to the mitochondrial matrix or to presynaptic boutons of cortic

193 ession of Grx1-roGFP2 targeted either to the mitochondrial matrix or to the cytoplasm.

194 significantly increased CIV enzyme activity, mitochondrial matrix oxidant burden, and sensitivity to

195 or the efficient import of proteins into the mitochondrial matrix, particularly if the function of th

196 of cyclophilin D (CypD, also called Ppif), a mitochondrial matrix peptidyl prolyl isomerase and apopt

197 n D (which is encoded by the Ppif gene) is a mitochondrial matrix peptidyl-prolyl isomerase known to

198 Cyclophilin D (CypD) is a mitochondrial matrix peptidyl-prolyl isomerase that regu

199 Cyclophilin-D (Cyp-D) is a mitochondrial matrix peptidyl-prolyl isomerase.

200 Drosophila motor neurons (MNs), we show that mitochondrial matrix pH (pHm), inner membrane potential

201 by the Lon-type AAA+ ATPase protease of the mitochondrial matrix, Pim1.

202 ting that protein phosphorylation within the mitochondrial matrix plays a mechanistic role in regulat

203 tein on which Fe-S clusters are built in the mitochondrial matrix, plays a central role in the biogen

204 Bovine heart mitochondrial matrix preparations were prepared free fro

205 Maturation of Rip1 occurs within the mitochondrial matrix prior to its translocation across t

206 on of the protein-folding environment in the mitochondrial matrix promotes ClpP-mediated generation o

207 independently of the rest of the complex by mitochondrial matrix protease ClpXP, which selectively r

208 reduced activity of clpp-1, which encodes a mitochondrial matrix protease homologous to bacterial Cl

209 Here we identify the novel mitochondrial matrix protease Ste23 in yeast, a homologu

210 Upregulation of mitochondrial matrix proteases and heat shock proteins w

211 hat in Arabidopsis (Arabidopsis thaliana), a mitochondrial matrix protein (EMB1793, At1g76060), which

212 e the involvement of Trap1, an Hsp90-related mitochondrial matrix protein and a member of the mitocho

213 ealed a role for an evolutionarily conserved mitochondrial matrix protein called Mam33 in Saccharomyc

214 s indicate that structural determinants on a mitochondrial matrix protein can govern its mitophagic f

215 The mitochondrial matrix protein cyclophilin D (CypD) is an

216 show that genetic deletion (Ppif-/-) of the mitochondrial matrix protein cyclophilin D (CypD) preven

217 Here we show that mice deficient for the mitochondrial matrix protein cyclophilin D (CypD) show r

218 ding studies suggested that LKT binds to the mitochondrial matrix protein cyclophilin D.

219 -color PALM shows that the freely diffusible mitochondrial matrix protein is largely excluded from th

220 The mitochondrial matrix protein isocitrate dehydrogenase 2

221 Mne1 is a mitochondrial matrix protein loosely associated with the

222 Mitochondrial ferritin (FtMT) is a mitochondrial matrix protein that chelates iron.

223 anslational processing and localization of a mitochondrial matrix protein was identified, which may i

224 StAR, a mitochondrial matrix protein, acts on the outer mitochon

225 However, the role of HSP60, a mitochondrial matrix protein, is somewhat controversial

226 In vivo targeting of a newly synthesized mitochondrial matrix protein, MRP2, was also inhibited d

227 ence, GLT-1 was shown to colocalize with the mitochondrial matrix protein, ubiquinol-cytochrome c red

228 human acetyl-CoA synthetase 2 (AceCS2) is a mitochondrial matrix protein.

229 Within the mitochondrial matrix, protein aggregation activates the

230 Here, we show that the mitochondrial matrix proteins 4-Nitrophenylphosphatase d

231 Virtually all mitochondrial matrix proteins and a considerable number

232 we present a phosphoproteomic screen of the mitochondrial matrix proteins and begin to establish the

233 In this study, we show that mitochondrial matrix proteins display surprisingly diffe

234 t-dispersed bc(1) complex was incubated with mitochondrial matrix proteins followed by dialysis in th

235 ant homolog Icp55 processes several imported mitochondrial matrix proteins leading to their stabiliza

236 We find that different mitochondrial matrix proteins undergo mitophagic degrada

237 It is known that different mitochondrial matrix proteins undergo mitophagy with ver

238 mHsp60-mHsp10 assists the folding of mitochondrial matrix proteins without the negative ATP b

239 ease that controls the selective turnover of mitochondrial matrix proteins, with potent inhibitors an

240 ferent subcellular compartments and maps the mitochondrial matrix proteome of Drosophila muscle to de

241 Lon protease, a major degradation enzyme in mitochondrial matrix, recognized and degraded mitochondr

242 How mtGTP that is trapped within the mitochondrial matrix regulates the cytosolic calcium inc

243 -binding proteins human Sod1 and Crs5 to the mitochondrial matrix results in growth impairment on non

244 g a genetically encoded Ca(2+) sensor in the mitochondrial matrix revealed that lack of MICU increase

245 Conversely, an increase in mitochondrial matrix ROS was found to deglutathionylate

246 on of the protein-folding environment in the mitochondrial matrix selectively upregulates the express

247 o the mtDNA D-loop is directed away from the mitochondrial matrix, so it is unlikely to interact with

248 fusions give EM contrast exclusively in the mitochondrial matrix, suggesting that both the N and C t

249 the outer mitochondrial membrane and in the mitochondrial matrix, suggesting the existence of distin

250 Yeast mutants lacking the mitochondrial matrix superoxide dismutase (SOD2) enzyme,

251 Within the mitochondrial matrix, superoxide is converted to hydroge

252 ne proposed mechanism of cardioprotection is mitochondrial matrix swelling.

253 se in ROS signaling and [Ca(2+)](i), whereas mitochondrial matrix-targeted Mn-SOD (SOD-II) augmented

254 Here, we report the finding of a mitochondrial matrix-targeted protein phosphatase 2C fam

255 We show here by employing a newly developed mitochondrial matrix-targeted superoxide indicator, that

256 ite classical nuclear localization signal, a mitochondrial matrix targeting sequence and the classica

257 t bursts of superoxide production within the mitochondrial matrix that are detected using the superox

258 rtuin 3) is the major deacetylase within the mitochondrial matrix that promotes aerobic metabolism an

259 of green fluorescent protein targeted to the mitochondrial matrix, that the engagement of plasma memb

260 presence of specific ceramide targets in the mitochondrial matrix, the occupation of which triggers p

261 xin, a conserved iron-binding protein of the mitochondrial matrix, thought to supply iron for formati

262 oth conditions requiring ATP import into the mitochondrial matrix through the ADP/ATP carrier.

263 STP via impaired calcium extrusion from the mitochondrial matrix through the mitochondrial permeabil

264 Pyruvate enters the mitochondrial matrix through the mitochondrial pyruvate

265 modulates the leak of protons back into the mitochondrial matrix, thus controlling reactive oxygen s

266 ling the stress of protein misfolding in the mitochondrial matrix to activate nuclear-encoded mitocho

267 f cisplatin from Platin-M locally inside the mitochondrial matrix to attack mtDNA and exhibited other

268 Here we find that GzmA accesses the mitochondrial matrix to cleave the complex I protein NDU

269 ion channel that transports Ca(2+) into the mitochondrial matrix to modulate metabolism.

270 ter (MCU) facilitates calcium entry into the mitochondrial matrix to stimulate metabolism.

271 l respiratory complex pumps protons from the mitochondrial matrix to the intermembrane space, it buil

272 when the NifH polypeptide is targeted to the mitochondrial matrix together with the NifM maturase.

273 e that guarantees Ca(2+) accumulation inside mitochondrial matrix upon increases in cytosolic Ca(2+).

274 t local and transient H2O2 production in the mitochondrial matrix upon inhibition of the endoplasmic

275 ducing equivalents NADH and FADH(2) Although mitochondrial matrix uptake of Ca(2+) enhances ATP produ

276 ein abundance and inhibition of MCU-mediated mitochondrial matrix uptake of Ca(2+) We also found that

277 fect of TCA cycle substrates on MCU-mediated mitochondrial matrix uptake of Ca(2+), mitochondrial bio

278 Several flavin-dependent enzymes of the mitochondrial matrix utilize NAD(+) or NADH at about the

279 on products, ADP, is transported back to the mitochondrial matrix via the antiporter, again through a

280 des evidence that the proton uptake from the mitochondrial matrix via the proton inlet half channel p

281 nternal standards, whereas the corresponding mitochondrial matrix volume is determined via immunoblot

282 lasts was intact, whereas ATP content in the mitochondrial matrix was lower than that in control cell

283 visualize the cristae invaginations into the mitochondrial matrix was possible in mitochondria with M

284 In vitro transport of the CuL into the mitochondrial matrix was saturable and temperature-depen

285 edox-sensitive optical probe targeted to the mitochondrial matrix, we found that calcium entry during

286 at the high nucleotide concentrations of the mitochondrial matrix, weak nucleotide binding constants

287 mitochondrial protein thiols exposed to the mitochondrial matrix were selectively S-nitrosated under

288 heme requires the uptake of glycine into the mitochondrial matrix where glycine is condensed with suc

289 or nucleus, PDC normally resides within the mitochondrial matrix where it converts pyruvate to acety

290 Mmp37p is located in the mitochondrial matrix where it is peripherally associated

291 the cytosol, but complexed by Mg(2+) in the mitochondrial matrix, where [Mg(2+)] is tenfold higher.

292 teolytically processed after import into the mitochondrial matrix, where it forms a homotrimeric comp

293 Pet117 is shown to reside in the mitochondrial matrix, where it is associated with the in

294 Sirtuin 3 (SIRT3) is localized in the mitochondrial matrix, where it regulates the acetylation

295 find that SCC is directly imported into the mitochondrial matrix, where its N-terminal sequence is c

296 mature hBFIT2 is shown to be located in the mitochondrial matrix, whereas the paralog "cytoplasmic a

297 ng chain acyl-coenzyme A (acyl-CoA) into the mitochondrial matrix, which requires the action of carni

298 nctional linkage between the cytosol and the mitochondrial matrix with a specific focus on metabolic

299 reased accessibility of palmitoyl-CoA to the mitochondrial matrix with the pore-forming peptide zerva

300 olism by linking biochemical pathways in the mitochondrial matrix with those in the cytosol [7].