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1 ical agent of anthrax, is a well-established model organism.
2 pathogens, using Neisseria meningitidis as a model organism.
3 mine the intracellular calcium level of this model organism.
4  Ag/AgCl), using Pseudomonas aeruginosa as a model organism.
5 ely record from nociceptive synapses in this model organism.
6 the fruit fly, Drosophila melanogaster, as a model organism.
7 d extensively as a medical and toxicological model organism.
8 te the functionalities of our framework on a model organism.
9 ntal pathways in an evolutionary informative model organism.
10 lity and enhanced brain size of the rat as a model organism.
11 standing of the virulence mechanisms of this model organism.
12 negative pathogen, Helicobacter pylori, as a model organism.
13 able in Halobacterium salinarum, an archaeal model organism.
14 abled virus-host interaction studies in this model organism.
15 ion in a genetically tractable multicellular model organism.
16 s targeting the Freshwater Pearl Mussel as a model organism.
17 often tricky to use or specific for a single model organism.
18 researchers to later question its value as a model organism.
19 the mechanisms of autophagy using yeast as a model organism.
20 facilitate synthetic biology efforts in this model organism.
21 composition was evaluated using chicken as a model organism.
22  consideration when selecting an appropriate model organism.
23  applicable for improving annotations in any model organism.
24 uisition and motor control in a light-weight model organism.
25  down by functional groups and translated to model organisms.
26 an extend lifespan and healthspan in various model organisms.
27 s remains poorly understood in all but a few model organisms.
28 a are poorly understood, particularly in non-model organisms.
29  cause defective ciliary function in several model organisms.
30 ype and knockout mammalian cell lines and in model organisms.
31 rized through decades of research in several model organisms.
32 cuitry and related disorders originates from model organisms.
33 developmental processes in any model and non-model organisms.
34 ht related omics data generated from several model organisms.
35 ging, and this role seems to be conserved in model organisms.
36 as testing these results on large samples of model organisms.
37 d maintained remains unclear, even in simple model organisms.
38 al research and discovery in human cells and model organisms.
39 ell types and molecules involved across many model organisms.
40  as muropeptides, which are recycled in many model organisms.
41 mple technology can likely be used with many model organisms.
42 perimental evolution mutations from multiple model organisms.
43 ssibility for investigators that study other model organisms.
44 uestions on chromatin dynamics in a range of model organisms.
45 ts that extend the lifespan of multicellular model organisms.
46 also confirmed by Western blot in a range of model organisms.
47 ata and radiation dosimetry for a variety of model organisms.
48 nalysis customary for research with nonhuman model organisms.
49 rated with the rigour of true experiments in model organisms.
50 construct the tomography of single cells and model organisms.
51  in the regulation of social behavior across model organisms.
52 d data interpretation in germline transgenic model organisms.
53 and emphasize differences between humans and model organisms.
54 iology research and development beyond a few model organisms.
55 rred to other medically relevant species and model organisms.
56 hway has seldom been achieved outside of the model organisms.
57 its that were once reserved for a few select model organisms.
58 f ageing remains challenging, even in simple model organisms.
59 y has long benefited from studies of classic model organisms.
60 ost exclusively limited to human studies and model organisms.
61  RNA silencing pathway in both model and non-model organisms.
62 d behavioural disease characteristics in MJD model organisms.
63  of miRNA-mRNA interactions in model and non-model organisms.
64 eria, such as Shewanella oneidensis MR-1, as model organisms.
65 mon in sequencing datasets obtained from non-model organisms.
66 urse, can be difficult when working with non-model organisms.
67 bolic profile and extend lifespan in various model organisms.
68 at complements knockout studies in cells and model organisms.
69 genes for functional validation in validated model organisms.
70 is oscillator has been well-characterized in model organisms(1,2), whether a similar oscillator exist
71 ly conserved, dynamic period across numerous model organisms(5-8), including mouse(9-18).
72 e maps of early embryos exist for nearly all model organisms, a fate map of the gastrulating human em
73 timulate natural transformation rates in the model organism Acinetobacter baylyi ADP1.
74 capacity of the mitochondrial genome, as the model organism and characterized its mitochondrial ribos
75 , here we used Streptococcus pneumoniae as a model organism and employed a proteomic approach that id
76 ntity of the active centromeres of a premier model organism and implicates retroelements as conserved
77 , a Gram-negative bacterium, was used as the model organism and releases variable chain length acylho
78 s for 12 species that include widely studied model organisms and also pathogens of clinical relevance
79 aniofacial and dental development in humans, model organisms and cell lines.
80 describe the performance of this tool on six model organisms and compare our results to two routinely
81 possible utility of partitiviruses infecting model organisms and disease vectors.IMPORTANCE Galbut vi
82 validate this classification using data from model organisms and engineered human cells, and show tha
83 anslational efficiency and mRNA stability in model organisms and human cell lines.
84                                   Studies in model organisms and humans have demonstrated dosage sens
85  annotations were curated in nine vertebrate model organisms and integrated into NCBI's Reference Seq
86 hly conserved in vertebrate and invertebrate model organisms and is currently not associated with a h
87 r investigations of diverse behaviors in non-model organisms and longer-term study of the mechanisms
88 int to evaluate the effects of these loci in model organisms and more precise substance use measures.
89  development of cell-free platforms from non-model organisms and multiplexed strategies for rapidly a
90 omics readout to complex tissue samples from model organisms and patient-derived whole blood.
91 es and gene families have been developed for model organisms and several important crops; however, a
92 m in disease, development and aging of small model organisms and single cells.
93 r, so far these have only been identified in model organisms and some natural systems.
94 nisms has been enhanced through the study of model organisms and the use of sophisticated genetic, bi
95 s a basis for further functional analyses in model organisms and translation to mammalian systems.
96 n of polymerase delta-knockout cell lines or model organisms and, therefore, the understanding of the
97 in transporter-deficient rats as a secondary model organism, and translational significance of preven
98 lied this method to eukaryotic and bacterial model organisms, and show that the resulting lamellae ar
99 isease models by inducing tumor formation in model organisms, and the relations between cell line cel
100 bases for environmental bacteria compared to model organisms, and the technical difficulties of metag
101 ociated with these ribosomes in seeds of the model organism Arabidopsis (Arabidopsis thaliana).
102 these families in plants-with a focus on the model organism Arabidopsis-is presented.
103 population genomic datasets derived from non-model organisms are efficiently analyzed via the paralle
104                                              Model organisms are extensively used in research as acce
105                              Non-traditional model organisms are typically defined as any model the d
106 he lack of leveraging evidence from multiple model organisms as well as the lack of expert curation a
107  parametric models previously established in model organisms as well as two nonparametric approaches
108 go-adapter-mediated dynein activation in the model organism Aspergillus nidulans Specifically, we fou
109 tial for controlling potassium uptake in the model organism Bacillus subtilis and several other bacte
110 f activity regulation in the sole RNR of the model organism Bacillus subtilis.
111 onserved between vertebrate and invertebrate model organisms, but currently abnormalities in CDK19 ar
112 n proposed for predicting essential genes in model organisms by integrating multiple biological data
113 e of neuropeptides in neural tissue from the model organism C. borealis.
114 nalyzed the simple egg-laying circuit in the model organism C. elegans We identified all the cells th
115 ides, a family of signaling molecules in the model organism C. elegans.
116 ersus anti-longevity status of genes for two model organisms (C. elegans and S. cerevisiae) using the
117 (1-42) peptide of Alzheimer's disease in the model organism Caenorhabditis elegans Our results pose a
118                                  We used the model organism Caenorhabditis elegans to identify geneti
119  been studied in an in vivo system using the model organism Caenorhabditis elegans.
120 tazoans and have been best described for the model organism Caenorhabditis elegans.
121 networks in multicellular settings, from the model organism, Caenorhabditis elegans, to humans.
122          Here we utilize a tractable genetic model organism, Caenorhabditis elegans, to study the eff
123 gger dose-dependent lethality in vivo in the model organism, Caenorhabditis elegans.
124                        Artificially selected model organisms can reveal hidden features of the geneti
125 ed the structure of the CAK complex from the model organism Chaetomium thermophilum at 2.6- angstrom
126 an immune genes is based on the well-studied model organism chicken (Gallus gallus).
127  genetic and physiological studies using the model organism Chlamydomonas reinhardtii, have revealed
128 nt-derived xenografts, and organs on a chip, model organisms continue to thrive with a combination of
129  that the experimental advantages of smaller model organisms could be exploited to study the biology
130                          We produced dormant model-organism cultures using an acidification model and
131 w provide a framework to efficiently harness model organism data in support of clinically relevant ps
132 improve diagnostic accuracy by incorporating model organism data.
133 ept, we implemented PedigreeNet at the maize model organism database, MaizeGDB.
134  of Genome Resources, a collaboration of six model organism databases (MODs) and the Gene Ontology Co
135  are also freely distributed through partner model organism databases and meta-databases.
136    In summary, modEnrichr leverages existing model organism databases and other resources to facilita
137 Genome Resources brings together a number of Model Organism databases to pool knowledge and tools.
138 oss the tree of life; however, outside a few model organism databases, genomic data are limited in th
139 uding the Gene Ontology, UniProt and several model organism databases.
140 rces website, the joint portal of NIH-funded model organism databases.
141       We apply GxEMM to a range of human and model organism datasets and find broad evidence of conte
142                                   Studies of model organisms defined intersecting signaling pathways
143                            Recent studies in model organisms demonstrate that the aging process is fr
144 sistant Fusarium species, and the mycetozoan model organism Dictyostelium discoideum Our results show
145 cept, we have used this CRISPR-E test in the model organism Dictyostelium discoideum to demonstrate t
146  response is conserved in the more primitive model organism Dictyostelium discoideum using a microflu
147  transcription comes largely from studies in model organisms doubling rapidly.
148 ordinarily common in wild populations of the model organism Drosophila melanogaster Like for most vir
149 nockdown of the SCAF4 ortholog CG4266 in the model organism Drosophila melanogaster resulted in impai
150                             Here, we use the model organism Drosophila melanogaster to delineate how
151                               In the popular model organism Drosophila melanogaster, gene editing has
152 riation in walking kinematics in the genetic model organism Drosophila.
153 ted and mostly biased towards one particular model organism (Drosophila).
154                                              Model organisms enable the analysis of both the tumor an
155 experimentally most thoroughly characterized model organism Escherichia coli not all tRNA modificatio
156 g a metabolic network reconstruction for the model organism Escherichia coli str.
157 o sub-networks on one of the best researched model organisms, Escherichia coli.
158 s compared with their dynamics in humans and model organisms, especially in body sites other than the
159 dEnrichr is an expansion of Enrichr for four model organisms: fish, fly, worm and yeast.
160 earning principles, it can be applied across model organisms, fluorescent indicators, experimental mo
161  how they support the use of Drosophila as a model organism for biological discovery and translationa
162 ces cerevisiae made this organism a suitable model organism for elucidating molecular mechanisms of c
163 by application on Enterococcus faecalis as a model organism for Gram-positive bacteria.
164 ck production and their increasing role as a model organism for human physiology, knowledge about the
165 ages with Mycobacterium marinum, a surrogate model organism for M. tuberculosis, and found that the e
166 ematode Caenorhabditis elegans, an important model organism for neuroscience research.
167             Using vaccinia virus (VACV) as a model organism for other Orthopoxviruses, CRISPR-Cas9 te
168    The medaka is a fish that has served as a model organism for over a century, yet there is still mu
169 , we present an overview of Xenopus as a key model organism for regeneration research and highlight h
170  mouse, Acomys spp., is a recently described model organism for regeneration studies.
171 berian hamster (Phodopus sungorus) genome, a model organism for seasonal physiology research, to faci
172                   Because the zebrafish is a model organism for skin pattern formation, we focus spec
173 s help to further establish P. leucopus as a model organism for studies of emerging infectious diseas
174 rscore the potential importance of bats as a model organism for studies of vocal plasticity, includin
175 a melanogaster is a unique, powerful genetic model organism for studying a broad range of biological
176  neuroinvasive virus that has been used as a model organism for studying common properties of all her
177 lanogaster has historically been a workhorse model organism for studying developmental biology.
178 ges of zebrafish have made this an essential model organism for studying lymphatic development, the e
179  In contrast, recent studies in mice-a major model organism for studying neurobiological sex differen
180  (EFB), Rousettus aegyptiacus, to serve as a model organism for studying NiV in bats.
181 ive bacterium Bacillus subtilis has become a model organism for studying regulatory networks directin
182  equal and constant lengths-is the canonical model organism for studying size control of organelles.
183  cyanobacterium Synechococcus elongatus is a model organism for the study of circadian rhythms.
184 ighlight that zebrafish may provide a useful model organism for the study of the genetic bases of non
185 f nanopharmaceuticals using zebrafish as the model organism for therapeutic assessment, biodistributi
186 ch, a passerine songbird species and a major model organism for vocal learning studies.
187     The mouse is one of the most widely used model organisms for genetic study.
188 llular industrial oleaginous microalgae, are model organisms for microalgal systems and synthetic bio
189 ted by the establishment of different animal model organisms, from flies to mammals.
190                                              Model organism genomes offer both additional training se
191 ing the whole range from draft to "complete" model organism genomes.
192 covered by IMG/M and resources for human and model organism genomics include Ensembl, UCSC Genome Bro
193  update in microbial genomes while human and model organism genomics resources include Ensembl, Ensem
194                 Among eukaryotes, a group of model organisms has been employed with great success to
195    Chemical-genetic interaction profiling in model organisms has proven powerful in providing insight
196                                  Research in model organisms has provided substantial insight into th
197 that exploration beyond the well-established model organisms has the potential to increase our knowle
198  has been extensively annotated and studied, model organisms have been less explored.
199                                     Although model organisms have provided much insight into this pro
200                 While preclinical studies in model organisms have raised some on-target toxicity conc
201             Research on astronaut health and model organisms have revealed six features of spacefligh
202                                 Unlike other model organisms, however, the genomic resources for babo
203 foundation for the use of the zebrafish as a model organism; however, characterisation of the zebrafi
204 ions in acidic biotopes, and is an important model organism in astrobiology.
205 dworm Caenorhabditis elegans is a laboratory model organism in biology.
206                      The rat is an important model organism in biomedical research for studying human
207         Caenorhabditis elegans is a valuable model organism in biomedical research that has led to ma
208 cod (Gadus morhua) has recently emerged as a model organism in environmental toxicology studies, and
209  well-studied necrotrophic fungus taken as a model organism in fungal plant pathology, given its broa
210 ate model in ageing research and an emerging model organism in genomics, regenerative medicine, devel
211             Escherichia coli is an important model organism in microbiology and a prominent member of
212 sa, B. subtilis and S. aureus were used as a model organism in this study.
213 es of mutant alleles have been successful in model organisms in determining what processes depend on
214 R. prolixus as vectors of Chagas disease and model organisms in insect physiology, the original JH th
215 f animal species lend themselves to becoming model organisms in multiple biological disciplines: one
216 the past, present, and future of brown algal model organisms in relation to the opportunities and cha
217 een established through studies conducted in model organisms in the Angiosperms.
218                               In particular, modeling organisms in the ocean system must integrate pa
219 types that are often collected in humans and model organisms including body images and whole-genome g
220 generation of gene knockouts in a variety of model organisms including zebrafish, and can be used to
221 drion shows striking differences from common model organisms, including fundamental processes such as
222 issue and cellular NAD(+) levels in multiple model organisms, including rodents and humans.
223 Additionally, we compiled polytracts of four model organisms into a Track Hub which can be integrated
224 gnalis and points out that this multipurpose model organism is an excellent, contemporary choice for
225                                           In model organisms, it impairs PKA (protein kinase A) phosp
226 ancy within the non-pathogenic mycobacterial model organism M. smegmatis (Msmeg), to identify genes r
227 -3 can infect Nicotiana benthamiana, a plant model organism, makes new opportunities available for re
228 nces found within the organ systems of these model organisms may highlight generalizable mechanisms t
229                           With data from two model organisms (mice, zebrafish) and five laboratories,
230 me, we applied our method to four additional model organisms - mouse, fly, worm and yeast - and ident
231 th recombineering into the chromosome of the model organism Mycobacterium smegmatis.
232              This was demonstrated using two model organisms, namely Bacillus subtilis and Escherichi
233 ere, using a forward genetic approach in the model organism Neurospora crassa, we identified two alle
234                                          The model organism Nitrobacter vulgaris produced only trace
235 ontains C-type lectins from cow, chosen as a model organism of agricultural interest for which the re
236 Although fruit flies are a common laboratory model organism of choice, there is relatively little und
237 oxetine in the zebrafish embryo - an aquatic model organism of intermediate complexity.
238 eds of nanometers, which is useful for small model organisms or for locations near specific cells.
239             The project has been extended to model organisms, particularly the mouse.
240                We observe that incorporating model organisms' protein-protein interactions does not m
241 for the human, mouse and other commonly used model organism proteomes.
242    AB569 was also efficacious at killing the model organism Pseudomonas aeruginosa in biofilms and in
243 fferences in ribosome occupancy patterns for model organisms ranging from yeast to mammals.
244  to date has come from studies of laboratory model organisms, recent studies have used a more diverse
245                                              Model organism research has generated extensive genomic
246 o various environmental stimuli in a classic model organism Saccharomyces cerevisiae has not been sys
247 e focus on describing key helicases from the model organism Saccharomyces cerevisiae that contribute
248 nce in establishing a Drosophila core of the Model Organisms Screening Center for the Undiagnosed Dis
249 ndings and genetic insights in non-mammalian model organisms serve to revise fundamental knowledge on
250 re predators learn to differentiate harmful "model" organisms (stinging Hymenoptera) from harmless "m
251                                              Model organism studies in yeast and Drosophila reveal an
252 easurements from individual small biological model organisms such as C. elegans or isolated single ce
253 f the full set of tRNA modification genes in model organisms such as Escherichia coli K12.
254 ys distinct features that are not present in model organisms such as Escherichia coli.
255              While siRNA libraries exist for model organisms such as mice, no CHO-specific library is
256  molecules and span the range from primitive model organisms such as Sacchaomyces cerevisiae, which a
257 ling study of their regulatory mechanisms in model organisms such as the budding yeast Saccharomyces
258 tudies of regenerating tissues in laboratory model organisms - such as acoel worms, frogs, fish and m
259             Recent work has leveraged simple model organisms, such as Caenorhabditis elegans and Dros
260                                              Model organisms, such as Drosophila, can help to identif
261 or ageing pathways previously highlighted in model organisms, such as the response to DNA damage, apo
262 l theories of episodic memory, evidence from model organisms suggests that the cornu ammonis 3 (CA3)
263                  Our genetic analysis in two model-organisms suggests a critical and conserved functi
264 ical processes and signaling pathways for 12 model organisms that can be analyzed with a powerful fra
265                                         As a model organism the zebrafish has been chosen due to its
266               Values were determined for two model organisms, the 'Proteobacteria' Ralstonia eutropha
267           In mice and other well-established model organisms, the relatively low rate of isoform quan
268  as a genetic system, but like other classic model organisms, this rise to prominence predated the di
269                       The use of tomato as a model organism to study elongation presents an opportuni
270 g of this important pathogen, rendering it a model organism to study eukaryotic biology and microbial
271 referred to as 'Aiptasia') are an attractive model organism to study this process, but they are large
272 a melanogaster, a fruit fly, is an exquisite model organism to understand neurotransmission.
273 al models, coupled with the use of humans as model organisms to accelerate the identification of the
274 and developmental biology tools available in model organisms to address novel biological mechanisms t
275 his approach is adaptable to all microscopic model organisms to facilitate a thorough quantification
276 rchers to extend beyond the set of classical model organisms to include novel species from less-studi
277 btilis and Gram-negative Escherichia coli as model organisms to monitor bacterial concentration, deca
278                         Arthropods are ideal model organisms to study biomineralization because they
279 reasingly embracing the use of multicellular model organisms to test the role of specific chromatin a
280 rimitive deuterostomes and have been used as model organisms to understand chordate biology because o
281 iologists are drawn to this system as a new "model organism" to study complex disease phenotypes and
282 rerio has become one of the major vertebrate model organisms used in biomedical research.
283                 Using single cell yeast as a model organism, we found that reducing yeast histone pro
284                             Using yeast as a model organism, we have shown previously that its two HI
285                  Here, using Drosophila as a model organism, we show that rapamycin-mediated alterati
286                         Using the chick as a model organism, we show that vertebrate Pax6 interacts w
287                                      In both model organisms, we recapitulated previously reported TE
288                               Using salps as model organisms, we studied the effect of microplastic i
289 ueprints for biological experiments in those model organisms, where G4 structures may play a role.
290 periment-specific library generation for non-model organisms, which we demonstrate using the malaria
291     Research on the molecular ecology of non-model organisms, while previously constrained, has now b
292                     Established and emerging model organisms will be considered alike, illuminating b
293                  As an optically transparent model organism with an endothelial blood-brain barrier (
294 rhabditis elegans has long been a laboratory model organism with no known natural pathogens.
295        Given that the rat is a more suitable model organism with regard to surgical interventions and
296                The availability of a genetic model organism with which to study key molecular events
297              As it is not possible to infect model organisms with human cytomegalovirus, the aim of t
298 epth and short-read sequencing data from non-model organisms with limited sample sizes.
299 d investigations of the regulatory genome of model organisms, with the potential of moving to an arra
300            It is particularly useful for non-model organisms without reference genomes and can be use

 
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