ライフサイエンスコーパス: molecular mechanism

1 way toward LDH inhibition through this novel molecular mechanism.

2 ions, suggesting the presence of overlapping molecular mechanisms.

3 nts' pathogenicity in terms of the perturbed molecular mechanisms.

4 ely, suggesting their regulation by distinct molecular mechanisms.

5 in's functionality and a view of its complex molecular mechanisms.

6 modification" as a tool to study biological molecular mechanisms.

7 fluence gene expression through a variety of molecular mechanisms.

8 interfere with STAT3 signaling by different molecular mechanisms.

9 rail is well equipped for uncovering complex molecular mechanisms.

10 ckout (VDR(DeltaPC)) mice to investigate the molecular mechanisms.

11 types in CRSsNP were controlled by different molecular mechanisms.

12 unctional studies of gene regulation and QDR molecular mechanisms across the Pentapetalae.

13 urther studies are needed to investigate the molecular mechanism and overall clinical incidence of CO

14 recent advances in our understanding of the molecular mechanisms and cellular bases underlying these

15 To gain insight into the molecular mechanisms and determinants of gene expression

16 Uncovering the molecular mechanisms and function of HE4 overexpression

17 enges of moving from genetic associations to molecular mechanisms and highlights efforts to identify

18 t the analysis of these mutants revealed the molecular mechanisms and logic of the cell cycle, identi

19 l therapeutic strategies informed by defined molecular mechanisms and neural circuits and targeted to

20 To identify the molecular mechanisms and novel therapeutic targets of la

21 ve transformed our ability to link genetics, molecular mechanisms and phenotypes.

22 ression of tumors, uncovering the underlying molecular mechanisms and potential therapies.

23 To date, explanatory molecular mechanisms and the influence of exercise inten

24 derstand the coherence of phenotype-specific molecular mechanisms and the potential for therapeutic i

25 s our current knowledge of the biochemistry, molecular mechanisms, and biological functions of mRNA m

26 tive (ER+) breast cancer, but the underlying molecular mechanisms are largely unknown.

27 Many drivers have been identified, but their molecular mechanisms are largely unknown.

28 t also hampers its treatment; the underlying molecular mechanisms are poorly understood and warrant i

29 Molecular mechanisms associated with biochar-elicited su

30 r, little information is known regarding the molecular mechanisms associated with the regulation of t

31 To explore the potential molecular mechanism behind our findings, we applied syst

32 However, the molecular mechanisms behind their dual protease and liga

33 ferentiation and synaptic plasticity but the molecular mechanisms behind these processes are still el

34 by mediating IL-17A-driven effects, but the molecular mechanism by which IL-17A regulates IkappaBzet

35 The molecular mechanism by which plants defend against plant

36 However, the molecular mechanism by which proteoglycans regulate sign

37 The molecular mechanism by which TCF21 regulates SMC phenoty

38 However, the molecular mechanism by which the OX40 cosignaling regula

39 inked to disease activity(3-5); however, the molecular mechanism by which these fibroblasts different

40 However, the molecular mechanisms by which activation of defence redu

41 The molecular mechanisms by which animals integrate external

42 obe-arbovirus interactions and summarize the molecular mechanisms by which commensal microbes act on

43 Recent data have begun to uncover the molecular mechanisms by which inflammation - driven by T

44 Yet, the molecular mechanisms by which METH causes neurodevelopme

45 However, the molecular mechanisms by which mucus affords this protect

46 However, the molecular mechanisms by which NLRP6 function is inhibite

47 The molecular mechanisms by which one ancestral rDNA set is

48 in SSc and CD reveals the complexity of the molecular mechanisms by which polymorphisms affect disea

49 ssibly through direct physical interactions, molecular mechanisms by which they interact are not clea

50 Here we explored the molecular mechanisms by which Trial 2 achieves the essen

51 of NRF2 is oncogenic, although the detailed molecular mechanisms by which uncontrolled NRF2 activati

52 All coronaviruses utilize a molecular mechanism called programmed -1 ribosomal frame

53 We show the cellular and molecular mechanisms contributing to the dysfunctional i

54 However, molecular mechanisms contributing to the pathogenesis of

55 Although many molecular mechanisms controlling developmental processes

56 However, the molecular mechanisms controlling DG formation and functi

57 re than one cell type expresses CFTR and the molecular mechanisms controlling its transcription are l

58 ve important insights into the corresponding molecular mechanisms controlling metabolic plasticity in

59 However, the molecular mechanisms controlling organ size, especially

60 , making it a unique system for studying the molecular mechanisms controlling the switch between prol

61 er, our data strongly suggest that different molecular mechanisms could operate in different plant sp

62 ic mechanisms have been identified, the full molecular mechanisms deriving CRC tumorigenesis are not

63 g with other proteins through three distinct molecular mechanisms: direct cell-cell interaction on ad

64 split, our current knowledge of cellular and molecular mechanism driving root development is mainly b

65 Our understanding of the molecular mechanisms driving metastasis is rudimentary.

66 he reproductive modes of these fungi and the molecular mechanisms driving the ectendomycorrhizal inte

67 However, the molecular mechanisms driving this response remain unclea

68 Here we examine the molecular mechanisms employed by pairs of inhibitors in

69 as a discussion on the possible cellular and molecular mechanisms explaining how this therapy provide

70 odium ion translocation pathway, providing a molecular mechanism for channel inhibition.

71 Here, we present a novel molecular mechanism for COVID-19 that provides therapeut

72 Here, we identify a molecular mechanism for detrimental effects of low mater

73 These data provide a molecular mechanism for how mMOR-1G regulates expression

74 gy transfer (FRET) microscopy to uncover the molecular mechanism for how surface sensing drives cell-

75 ) is one known method of subversion, but the molecular mechanism for IFNAR downregulation during IAV

76 The underlying molecular mechanism for its establishment is much less u

77 uring postnatal development and reveal a new molecular mechanism for mRNA localization in vertebrates

78 This precise molecular mechanism for SAMHD1 catalysis, reveals how SA

79 physiology to emerge, providing a plausible molecular mechanism for some lethal ventricular arrhythm

80 main sources of genomic instability, yet the molecular mechanisms for protecting forks from degradati

81 The molecular mechanisms for the photoconversion of fluoresc

82 utations of SRD5A2 to our structure suggests molecular mechanisms for their pathological effects.

83 To define molecular mechanisms for these diverse developmental def

84 tivity relies on acetylcholine, although the molecular mechanisms for this dependence are not thoroug

85 anscriptome analyses and can lead to precise molecular mechanisms for understanding complex human dis

86 r the first time a thermochemically feasible molecular mechanism from ocean iodine emissions to atmos

87 findings will enable screening for candidate molecular mechanisms from readily available neuroimaging

88 , transcription) are revealing how different molecular mechanisms generate regulatory variation, and

89 We speculate that the molecular mechanisms giving rise to the internal frictio

90 Here, we elucidate the previously unknown molecular mechanism governing the DNA-vWF interaction by

91 cidate the role of host genetics, underlying molecular mechanisms governing SARS-CoV-2 pathogenesis,

92 The molecular mechanisms governing such plasticity are undef

93 responsible for cleaving host IgA1, yet the molecular mechanism has remained unknown since their dis

94 This review discusses molecular mechanisms, implications of these findings, tr

95 However, the molecular mechanisms in CRSsNP are poorly understood com

96 tal model that defines multiple cellular and molecular mechanisms in HFpEF that could be a target for

97 Nevertheless, the molecular mechanisms in mammalian cells are not well und

98 We also find that BDNF rescues select molecular mechanisms in slow and fast muscle that may un

99 em affects physiological, psychological, and molecular mechanisms in the body, resulting in varying p

100 restrict cortical network plasticity but the molecular mechanisms involved are unclear.

101 e aim of this study was to elucidate various molecular mechanisms involved in different tissues of he

102 ategies to manage the disease in Brazil, the molecular mechanisms involved in resistance are still un

103 The cellular and molecular mechanisms involved in spontaneous prion forma

104 Transcriptome landscape reveals the molecular mechanisms involved in the improvement of frui

105 affecting the gut-immune-brain axis and the molecular mechanisms involved in this process were unkno

106 d selected seven cell shapes to describe the molecular mechanism leading to phenotypic diversity.

107 alk between STAT3 and EGFR pathways is a key molecular mechanism leading to resistance in pancreatic

108 ediated eIF2alpha phosphorylation, providing molecular mechanisms linking metabolism, protein synthes

109 ether Rap1A has the same ability or what its molecular mechanism might be.

110 olic profile both in humans and mice through molecular mechanisms not yet completely defined.

111 Previous theory has proposed a molecular mechanism of bound-state mobility based only o

112 This work furthers our understanding of the molecular mechanism of CD81 cholesterol sensing, how thi

113 Our results provide insight into the molecular mechanism of drug export and inhibition of a m

114 By understanding the molecular mechanism of erastin-induced cellular resistan

115 To decipher the molecular mechanism of estrogens at the estrogen recepto

116 Here we study the molecular mechanism of hGBP1 polymer formation as it is

117 Here, we show a molecular mechanism of how plants can sense parasitic Cu

118 Our results provide insights into the molecular mechanism of HSF2BP-S167L in human ovarian ins

119 In sum, we uncovered the molecular mechanism of HuR regulating Th17 cell function

120 Taken together, our results elucidated the molecular mechanism of indole-induced antibiotic toleran

121 gether, these data provide insights into the molecular mechanism of Nb23-mediated recognition of GFLV

122 the binding site of PES on the NMDAR and the molecular mechanism of potentiation are unknown.

123 tubulin tails and tail modifications in the molecular mechanism of protein diffusion along MTs.

124 gainst atomistic simulations, we explore the molecular mechanism of protein diffusion along MTs.

125 ontext for future work aiming at deciphering molecular mechanism of regulation of secondary metabolis

126 through tissue acquisition, to identify the molecular mechanism of resistance and to guide second-li

127 To enhance our understanding of the molecular mechanism of substrate cleavage, we have solve

128 Our findings reveal the molecular mechanism of the antagonistic gene paralogs RH

129 id bilayer is uncharacterized, let alone the molecular mechanism of the calcium transport activity.

130 esults provide a basis for understanding the molecular mechanism of the functional promiscuity of FPR

131 The results of this study elucidate the molecular mechanism of the Ras mutant-mediated developme

132 Herein, inspired by the molecular mechanism of thermally stable proteins, the sy

133 ts try to control their blood sugar, but the molecular mechanism of this 'metabolic memory' phenomeno

134 However, the molecular mechanism of transcription processing of Gh an

135 Taken together, our results support a molecular mechanism of transcriptional control that allo

136 nscriptional addiction phenomenon as well as molecular mechanisms of action of 3D genome-disrupting d

137 andidates is important for determining their molecular mechanisms of action.

138 wledge gap impairs efforts to understand the molecular mechanisms of AF and cardiac conduction phenot

139 we summarize recent findings concerning the molecular mechanisms of age-related heart failure and hi

140 or future studies on the characterization of molecular mechanisms of biofluorescence in amphibians, a

141 inheritance patterns, arrhythmic risks, and molecular mechanisms of CASQ2-CPVT was sought through an

142 Our studies define the molecular mechanisms of cell-specific alternative splici

143 sm a suitable model organism for elucidating molecular mechanisms of copper transport and homeostasis

144 This study investigates the molecular mechanisms of environmental factors in FECD pa

145 ially providing valuable information for the molecular mechanisms of ESCC.

146 However, the molecular mechanisms of genome replication and the inter

147 However, the underlying molecular mechanisms of how phosphoinositides act in the

148 This minireview summarizes the known molecular mechanisms of iron, zinc, and B vitamin proces

149 In our quest to determine the molecular mechanisms of its antiviral activity, we show

150 f RD3 has recently been established, but the molecular mechanisms of its inhibitory binding to RetGC

151 nsiderable advancements in understanding the molecular mechanisms of JCPyV infection, but this has mo

152 b genes could provide deep insights into the molecular mechanisms of KIRC.

153 two applications using Primo to examine the molecular mechanisms of known susceptibility loci and to

154 The molecular mechanisms of macrophage polarization are not

155 otif complexes abound in the literature, the molecular mechanisms of multivalent WW domain-PPXY assem

156 We report Spark-based INFERence of the molecular mechanisms of NOn-coding genetic variants (Spa

157 ides an excellent system for deciphering the molecular mechanisms of organogenesis, and has thus been

158 (PR) Klebsiella pneumoniae to determine the molecular mechanisms of PR and the role of polymyxin exp

159 t to the substantial body of research on the molecular mechanisms of resistance, understanding of how

160 rch community is in a race to understand the molecular mechanisms of severe acute respiratory syndrom

161 nesis, and our results shed new light on the molecular mechanisms of telomeric DDR and CD4 T-cell hom

162 utational and mutagenesis studies reveal the molecular mechanisms of the catalyzed reaction and of fi

163 Our studies not only reveal the molecular mechanisms of the nuclear import of IAV vRNP b

164 Here, we elaborate on the molecular mechanisms of these 2 emerging key pathways dr

165 We also reveal molecular mechanisms of these phenomena.

166 Thus, understanding the underlying molecular mechanisms of this condition is critical to de

167 1 (TORC1), was investigated to elucidate the molecular mechanisms of vitellogenesis regulation in the

168 on B cell responses to particulate Ags, the molecular mechanisms of which remain to be explored.

169 ovided pivotal new insights into the diverse molecular mechanisms presumed to drive tumour initiation

170 cant gaps remain in our understanding of the molecular mechanisms ProQ uses to interact with RNA.

171 the field, focusing on new insights into the molecular mechanisms regulating competitive behavior in

172 Despite its importance, the molecular mechanisms regulating DG neural circuit assemb

173 The molecular mechanisms regulating fibrosis in the heart ar

174 The molecular mechanisms regulating lymphocyte homing into l

175 This article will review the molecular mechanisms related to macrophage polarization

176 of the small GTPase MglA, but the underlying molecular mechanisms remain elusive.

177 Its underlying cellular and molecular mechanisms remain poorly understood.

178 Although the molecular mechanisms remain unclear, altered distributio

179 , maternal and fetal genetic factors and the molecular mechanisms remain unclear.

180 flammatory response; however, the underlying molecular mechanisms remain unclear.

181 d matrix polysaccharides, but the underlying molecular mechanisms remain unknown.

182 repress gene expression, yet the underlying molecular mechanism remains uncertain.

183 nteractions is suggestive of coherent/random molecular mechanisms, respectively.

184 However, the molecular mechanisms responsible for biased signaling ar

185 The resolution of the molecular mechanisms responsible for human reproductive

186 red with their younger counterparts, yet the molecular mechanisms responsible for the discrepancy are

187 ic phasic contractile activity; however, the molecular mechanisms responsible for the weaker lymphati

188 However, the molecular mechanisms responsible for this response remai

189 ion of NF-kappaB signaling by CARP-1 and the molecular mechanism(s) involved are unclear.

190 t enhancer accessibility could be one of the molecular mechanisms seeding evolutionary co-option.

191 However, the underlying molecular mechanism still remains elusive.

192 nalogs provided important insights as to the molecular mechanism that drives CSP receptor binding and

193 talization of macromolecules is a ubiquitous molecular mechanism that drives numerous cellular functi

194 Here, we report a molecular mechanism that enables cholinergic motor neuro

195 esults provide fundamental insights into the molecular mechanism that enables the dynamic regulation

196 fic regulation of RNA editing and identify a molecular mechanism that regulates ADAR substrate recogn

197 ole of KDM6A deficiency with a cell-specific molecular mechanism that underlies PDAC subtype definiti

198 has revealed exciting new insights into the molecular mechanisms that allow cells to change shape an

199 lls to malignant transformation, however the molecular mechanisms that allow for the propagation of c

200 Important questions remain regarding the molecular mechanisms that are responsible for the pathol

201 However, the molecular mechanisms that cause these cells to form are

202 In this review, we will summarize the molecular mechanisms that control epicardium-derived pro

203 Our results identify specific molecular mechanisms that drive FBRs in the CNS and have

204 The molecular mechanisms that drive these stalling events, h

205 The molecular mechanisms that enable sensory neurons to rema

206 These results identify molecular mechanisms that generate guides for DNA interf

207 Identifying the molecular mechanisms that give rise to genetic variation

208 the execution of motor actions; however, the molecular mechanisms that give rise to specific patterns

209 Identifying and understanding the molecular mechanisms that govern anhydrobiosis will lead

210 l nervous system synapses(1,2); however, the molecular mechanisms that govern astrocyte-synapse adhes

211 However, due to lack of in vivo studies, the molecular mechanisms that govern both early human heart

212 rea remains a major bottleneck in uncovering molecular mechanisms that govern inflammatory pain in th

213 Understanding the molecular mechanisms that govern the differentiation of

214 Nevertheless, the molecular mechanisms that govern this process remain unk

215 We summarize recent work in elucidating molecular mechanisms that govern three-dimensional chrom

216 The molecular mechanisms that guide T(reg) cell stability in

217 activity arises within the cochlea, but the molecular mechanisms that initiate this activity remain

218 arley gene content and implicates SDs in the molecular mechanisms that lead to the formation of this

219 y, ribosome profiling, and cryo-EM to define molecular mechanisms that lead to these ribosome stalls.

220 The molecular mechanisms that link these pathways, however,

221 sing these animal models has revealed shared molecular mechanisms that make Muller glia attractive ta

222 lineage is an exciting model for probing the molecular mechanisms that modulate the Notch signaling p

223 However, the molecular mechanisms that precipitate plaque rupture are

224 Exploring the molecular mechanisms that prevent inflammation during ca

225 owth in G(1) provides one of the long-sought molecular mechanisms that promotes cell size homeostasis

226 Molecular mechanisms that prompt or mitigate excessive a

227 preactive state, which provides insight into molecular mechanisms that regulate channel activation fr

228 However, the molecular mechanisms that regulate expression of the PD-

229 ) as an example, we studied the cellular and molecular mechanisms that regulate postnatal BAT growth.

230 e also been made in our understanding of the molecular mechanisms that regulate the transmission proc

231 are sexually dimorphic and the cellular and molecular mechanisms that regulate these differences are

232 However, the molecular mechanisms that regulate this dynamic process

233 al complications necessitates studies on the molecular mechanisms that regulate ZIKV pathogenesis.

234 rio vulgaris type I-C Cascade, revealing the molecular mechanisms that underlie RNA-directed complex

235 ent evidence about the tissue, cellular, and molecular mechanisms that underlie the reduction in pace

236 However, investigating the molecular mechanisms that underlie the regulation of pho

237 avior, but little is known about the precise molecular mechanisms that underlie this process.

238 Our study thus provides a unifying molecular mechanism through which dominant-acting calseq

239 However, the molecular mechanisms through which MIA imparts risk rema

240 hese findings identify key hypoxia-regulated molecular mechanisms through which PMNs directly induce

241 methylation at N4-position of cytidine is a molecular mechanism to fine tune base pairing specificit

242 ese data demonstrate that there are distinct molecular mechanisms triggering electrically induced and

243 depth bedside-to-bench analysis uncovers the molecular mechanism underlying a case of highly aggressi

244 However, the molecular mechanism underlying Fzr-mediated endoreplicat

245 Here, we discover that the molecular mechanism underlying Naked/NKD function relies

246 The identified molecular mechanism underlying the analgesic role of SGC

247 nding domain across phyla and underscore the molecular mechanism underlying the function of LOTUS dom

248 The molecular mechanism underlying the functional conversion

249 These findings unravel the molecular mechanism underlying the intriguing clinical a

250 tion of PKC(epsilon) appeared to be a likely molecular mechanism underlying this beneficial electroph

251 The molecular mechanism underlying this numerical control, h

252 on and provide a better understanding of the molecular mechanism underlying transformation by HPV.

253 Molecular mechanisms underlying adaptive targeted therap

254 omics reveals an unexpected diversity in the molecular mechanisms underlying conserved cellular funct

255 tically influence tumor progression, but the molecular mechanisms underlying ECM layering are poorly

256 data from GTEx and TOPMed identify potential molecular mechanisms underlying four of the 22 novel loc

257 echnological advances, new insights into the molecular mechanisms underlying glioma metabolism are ra

258 ded a comprehensive understanding of various molecular mechanisms underlying grafted tissues in water

259 Here, we review current understanding of the molecular mechanisms underlying hyaluronan and HAS2 regu

260 Little is known about the molecular mechanisms underlying hyperinflation and how i

261 However, the molecular mechanisms underlying increased antiapoptosis

262 he normal function of mitochondria, yet, the molecular mechanisms underlying IRGM-mediated quality co

263 Previous research to define the molecular mechanisms underlying JCPyV infection has most

264 The molecular mechanisms underlying NASH development remain

265 es the vast extent of sex differences in the molecular mechanisms underlying pair-bonding in prairie

266 ght-adapted states have been determined, the molecular mechanisms underlying photoactivation remain e

267 The molecular mechanisms underlying positional identity of t

268 Therefore, a better understanding of the molecular mechanisms underlying stress responses in beta

269 The molecular mechanisms underlying such a duality in CD5 fu

270 l information provides new insights into the molecular mechanisms underlying synaptic functions of AM

271 C, R800C, Y849C) on catalysis, unveiling the molecular mechanisms underlying Synj1-associated disease

272 l models from humans with DS to identify the molecular mechanisms underlying the brain phenotype asso

273 In this review, we discuss the molecular mechanisms underlying the establishment and ma

274 However, the molecular mechanisms underlying the failure of beta-cell

275 The molecular mechanisms underlying the formation of coronar

276 Despite high prevalence, the molecular mechanisms underlying the painful manifestatio

277 ll, these results will provide insights into molecular mechanisms underlying the primary metabolic re

278 al for the development of the brain, but the molecular mechanisms underlying the regulation of glial

279 s are known to regulate those processes, the molecular mechanisms underlying the relationship between

280 However, the molecular mechanisms underlying the role of PML-RARalpha

281 Although the molecular mechanisms underlying these ABO effects on VWF

282 The dysregulation of the molecular mechanisms underlying these processes may caus

283 pening have been well characterized, but the molecular mechanisms underlying this phenomenon continue

284 However, the genetic and molecular mechanisms underlying this process remain larg

285 The molecular mechanisms underlying this specificity remain

286 We discuss the molecular mechanisms underlying this surprising pleiotro

287 We discuss different molecular mechanisms underlying TRAIL-mediated apoptosis

288 rch has generated extensive knowledge of the molecular mechanisms underlying Wallerian degeneration,

289 The genes and molecular mechanisms underpinning circadian clocks in mu

290 cyte precursor cells (OPCs) and explored the molecular mechanism using RNA-sequencing assay.

291 To investigate the molecular mechanism, we utilize epidermal growth factor

292 To identify underlying molecular mechanisms, we performed genome-wide associati

293 Our results provide a cellular and molecular mechanism whereby activation of OXTRs exerts a

294 Altogether, these data establish a potential molecular mechanism whereby adversity during puberty can

295 HSPCs, leukemia, and their MSC niche, and a molecular mechanism whereby AML impairs normal hematopoi

296 Using organoid experiments, we identified a molecular mechanism whereby PGE(2) promotes Yap dephosph

297 s identify a plausible temperature-dependent molecular mechanism, which contributes to the robustness

298 ion require an improved understanding of the molecular mechanisms, which underlie preeclampsia pathop

299 lasticity that shares several attributes and molecular mechanisms with well-characterized forms of ho

300 reduce cocaine-seeking behavior, however the molecular mechanisms within the hippocampus that underli