ライフサイエンスコーパス: molecular replacement

1 been determined to a resolution of 3.0 A by molecular replacement.

2 phate), is determined to 2.3 A resolution by molecular replacement.

3 ructure of H256A to a resolution of 2.4 A by molecular replacement.

4 hine has been solved at 1.85-A resolution by molecular replacement.

5 An x-ray structure was determined by molecular replacement.

6 roup P41212, and the structure was solved by molecular replacement.

7 e has been determined to 2.5 A resolution by molecular replacement.

8 ylated human IFN-beta at 2.2-A resolution by molecular replacement.

9 resolution, and the structure was solved by molecular replacement.

10 e been phased using external information via molecular replacement.

11 the RCs in the unit cell were determined by molecular replacement.

12 l structure of Bacteroides fragilis CASDH by molecular replacement.

13 ucleoFind maps produced following successful molecular replacement.

14 he determination of the Cry11Ba structure by molecular replacement.

15 the structure to 4.5 angstrom resolution by molecular replacement.

16 he corresponding X-ray crystal structures by molecular replacement.

17 tfC crystal structure was solved at 2.7 A by molecular replacement.

18 a novel combination of homology modeling and molecular replacement.

19 Triton X-100 and the structure was solved by molecular replacement.

20 structure was solved to 1.5-A resolution by molecular replacement.

21 enzyme in phenazine biosynthesis, solved by molecular replacement.

22 ) was also determined at 2.6 A resolution by molecular replacement.

23 lized at pH 6.25 and its structure solved by molecular replacement.

24 iously, it was possible to use the method of molecular replacement.

25 on-inhibited W197I variant was determined by molecular replacement (2.2 A); it revealed a stabilized

26 The structure was determined by molecular replacement, a recently determined structure o

27 The structure was solved using molecular replacement, aided by an isomorphous derivativ

28 xMDFF, either fails to produce a solution by molecular replacement alone or produces an inaccurate st

29 Serial crystallographic data for molecular replacement already converges in 1,000-10,000

30 pection of the X-ray diffraction pattern and molecular replacement analysis revealed the orientation

31 ex was solved at a resolution of 3.0 A using molecular replacement and constitutes the first reported

32 ex was solved at a resolution of 2.5 A using molecular replacement and constitutes the first reported

33 d to 2.1 A resolution using a combination of molecular replacement and isomorphous replacement and re

34 structure of TeNT-LC, determined by combined molecular replacement and MAD phasing.

35 ylate has been solved using a combination of molecular replacement and noncrystallographic symmetry a

36 A using X-ray diffraction analysis based on molecular replacement and phase extension methods.

37 A resolution and the structure determined by molecular replacement and phase extension.

38 The OIH-1 structure was solved by molecular replacement and refined at 1.25 A resolution.

39 The structure has been solved by molecular replacement and refined at 1.8 A resolution.

40 The structure was solved by molecular replacement and refined at 2.0 A resolution.

41 from Arabidopsis thaliana has been solved by molecular replacement and refined at the resolution of 1

42 noclonal antibody (Mab231) was determined by molecular replacement and refined in a triclinic cell to

43 We solved the x-ray crystal structure by molecular replacement and refined the resulting model ag

44 The structures were solved by molecular replacement and refined to 2.1 (K+) and 2.35 A

45 =59.15 A, c=94.44 A) have been determined by molecular replacement and refined versus data to 2.0 A a

46 .9 A resolution; the structure was solved by molecular replacement and refined with an R-factor of 0.

47 Man-alpha 1,3-Man-OMe complex, determined by molecular replacement and refined with X-PLOR using NCS

48 Structure analysis by molecular replacement and refinement at 2.2A resolution

49 n fluorescent protein has been determined by molecular replacement and the model refined.

50 Molecular replacement and weak phasing information from

51 placed in the crystallographic unit cell by molecular replacement, and how initial phases computed f

52 The structures were determined by molecular replacement, and refined to 3.1 A (native) and

53 The SM3-MUC1 peptide structure was solved by molecular replacement, and the current model is refined

54 6 (lambda(em)max = 486 nm) was determined by molecular replacement, and the model was refined at 1.65

55 These crystalline properties permitted a molecular replacement approach based upon a beta-hairpin

56 Using a molecular replacement approach in mouse hippocampal neur

57 We have now used a molecular replacement approach on an AMPAR-null backgrou

58 In this review, we discuss a single-cell molecular replacement approach which should arguably adv

59 Applying a "molecular replacement" approach in hippocampal neurons d

60 Using "molecular replacement" approach in hippocampal neurons d

61 ure of the variant protein was determined by molecular replacement as a T(3)R(3) zinc hexamer.

62 tadecyl-CoA, and its structure was solved by molecular replacement at 1.4 A resolution.

63 esidues Asp 2-Asn 762 has been determined by molecular replacement at 1.9 A resolution and refined to

64 europneumoniae, a major porcine pathogen, by molecular replacement at 1.9 A resolution.

65 d the crystal structures of AgaA and AgaB by molecular replacement at 3.2- and 1.8 A-resolution, resp

66 s cerevisiae chorismate mutase was solved by molecular replacement at a resolution of 2.8 angstroms u

67 ture determined to 4.4-A resolution by using molecular replacement based on the structure of the beef

68 beta motifs with an accuracy high enough for molecular replacement based phasing.

69 Knowledge-based databases holding molecular replacements can be supportive in the optimiza

70 inal Src kinase (CSK) has been determined by molecular replacement, co-complexed with the protein kin

71 Through the method of Wide Search Molecular Replacement, developed here, they can be compl

72 ended in steps to 3.0 angstrom resolution by molecular replacement electron density modification and

73 Using in vitro and in vivo molecular replacement, electrophysiology, electron micro

74 Molecular replacement experiments revealed that the LRRT

75 Molecular replacement experiments show that both Spindly

76 Finally, we employed molecular replacement experiments using a knockdown resc

77 Using in vivo molecular replacement experiments, we find that these un

78 m for structure determination of lysozyme by molecular replacement followed by crystallographic refin

79 cage hydrocarbons are popular bioisosteres (molecular replacements) for commonly found para-substitu

80 itor, were determined at 2.0 A resolution by molecular replacement from a second crystal form and wer

81 native crystals in the space group P3(1), by molecular replacement from the 2.8 A model (1F88) solved

82 and in the absence of templates suitable for molecular replacement from the Protein Data Bank.

83 of the complex with Mg(2+)*OSB was solved by molecular replacement in space group P2(1)2(1)2.

84 tate at 2.03 A resolution that was solved by molecular replacement in the space group P6(5) with two

85 Molecular replacement in X-ray crystallography is the pr

86 tructures are determined using the method of molecular replacement, in which known related structures

87 l in phasing crystallographic data for which molecular replacement is hindered by the absence of suff

88 nderstanding of the signal-to-noise ratio in molecular replacement leads to the finding that, with da

89 The structure was solved by the molecular replacement method and refined at 1.7 A resolu

90 crystal structure of hCBG was solved by the molecular replacement method and refined at 2.7 A resolu

91 The structure was solved by the molecular replacement method and refined to a final R-fa

92 The structure was solved by the molecular replacement method and refined to an Rwork/Rfr

93 The structure was solved by the molecular replacement method and subsequently refined us

94 of IVD was solved at 2.6 A resolution by the molecular replacement method and was refined to an R-fac

95 The structure was solved by the molecular replacement method at 1.9 A resolution and ref

96 on method for the first crystal form and the molecular replacement method for the second crystal form

97 Both structures were solved by the molecular replacement method using different starting mo

98 initial solution was determined by using the molecular replacement method using the structure of the

99 otein or peptide can be determined using the molecular replacement method with the help of the GST st

100 The crystal structure was solved by the molecular replacement method, and the model has been ref

101 The structure was solved by the molecular replacement method, and the model has been ref

102 The molecular replacement method, starting with d(pGpC) of t

103 The molecular replacement method, with the NAP-2 tetramer as

104 The structures were solved by the molecular replacement method.

105 The structure was solved using the molecular replacement method.

106 id) complex were determined with the help of molecular replacement methods to 2.0A and 2.3A resolutio

107 bound to domain VI of calpain, determined by molecular replacement methods to 2.5A and 2.2A resolutio

108 tic domain joined by a linker, was solved by molecular replacement methods using independent search m

109 human plasminogen (K5HPg) has been solved by molecular replacement methods using K1HPg as a model and

110 ccus surface protein, has been determined by molecular replacement methods using K4Pg as a model, and

111 Molecular replacement methods were used to solve the str

112 as been determined to 1.9 A resolution using molecular replacement methods.

113 on of the "closed form" GlnBP-Gln complex by molecular replacement methods.

114 to 1.6 A spacing by anomalous scattering and molecular replacement methods.

115 n from electron cryomicroscopy was used as a molecular replacement model for initial phase determinat

116 h respect to the human Fc used as an initial molecular replacement model.

117 Molecular replacement (MR) is one of the most common tec

118 The structure was determined starting with a molecular replacement (MR) model identified by unsupervi

119 gle initial model obtained, for instance, by molecular replacement (MR).

120 re we show that, contrary to current belief, molecular replacement need not be restricted to the use

121 The recently developed NMR molecular replacement (NMR(2)) method dramatically reduc

122 elucidate the binding modes, we applied NMR molecular replacement (NMR(2)) structure calculations, b

123 we establish a comparable method, called NMR molecular replacement (NMR(2)).

124 Neither molecular replacement nor derivative methods had a suffi

125 pid carrier proteins, may also contribute to molecular replacement of disc membrane DHA-phospholipids

126 Moreover, molecular replacement of endogenous PSD-95 with the S561

127 tron density interpretation after phasing by molecular replacement or other methods remains a difficu

128 Despite extensive work, molecular replacement or the subsequent rebuilding usual

129 D has been solved to 2.3-A resolution using molecular replacement phases derived from human oxyhemog

130 CD has been solved to 3.0 A resolution using molecular replacement phases derived from the structure

131 was determined to1.9 A resolution using the molecular replacement phasing method.

132 Molecular replacement procedures, which search for place

133 he signal-to-noise ratio in likelihood-based molecular replacement searches has been developed to acc

134 A tungstate derivative confirmed the initial molecular replacement solution and identified an anion b

135 tant has been solved at 1.62 A resolution by molecular replacement starting from the structure of the

136 The structures have been solved using molecular replacement strategies, and the DHPR-NADH-2,6-

137 sential for synaptic potentiation by using a molecular replacement strategy designed to dissociate Ra

138 Using a viral-mediated molecular replacement strategy in rat hippocampal slices

139 We utilized a molecular replacement strategy in which exogenous SV2A w

140 pal pyramidal neurons, we used a single-cell molecular replacement strategy to replace all endogenous

141 Using a molecular replacement strategy with RNAi-mediated knockd

142 Using a molecular replacement strategy, we also revealed that a

143 he control of these two events, we performed molecular replacement studies in primary cultures of Syp

144 ral role in X-ray structure determination by molecular replacement, such information is rarely used i

145 The crystal structure has been solved using molecular replacement techniques and refined by simulate

146 To accomplish this, molecular replacement techniques are being used, where n

147 NAT2, aaNAT5b and paaNAT7 was detected using molecular replacement techniques.

148 The resulting model was used to solve by molecular replacement the X-ray structure of l-sfAFP to

149 ap from X-ray crystallography obtained after molecular replacement, the positions of the phosphate gr

150 crystal structure of LbPFK was solved using molecular replacement to 1.86 A resolution.

151 ycogenin and UDP-glucose/Mn2+ were solved by molecular replacement to 1.9 A using the orthorhombic cr

152 himurium bound to GMP has been determined by molecular replacement to 2.2 A resolution.

153 human low molecular weight PTPase solved by molecular replacement to 2.2 A.

154 encoded by the cobA gene, has been solved by molecular replacement to 2.7A resolution.

155 ontaining tripeptide have been determined by molecular replacement to 3.5 A and 2.4 A resolutions, re

156 as determined by X-ray crystallography using molecular replacement to a resolution of 2.9 A.

157 single-wavelength anomalous diffraction and molecular replacement to determine structures of the alp

158 We have used molecular replacement to solve the crystal structure of

159 the X-ray crystallographic phase problem in molecular replacement trials.

160 The phase problem was solved by molecular replacement using an AlphaFold model as the se

161 berculosis antigen 85B (ag85B), initially by molecular replacement using antigen 85C as a probe.

162 activity, was solved at 1.5 A resolution by molecular replacement using as the search model the solu

163 o-COR determined to a resolution of 2.4 A by molecular replacement using chalcone reductase as a sear

164 OPS) from Escherichia coli was determined by molecular replacement using coordinates given to us by R

165 A. aeolicus enzyme, which was determined by molecular replacement using E. coli KDO8PS as a model.

166 The structures were solved by molecular replacement using Escherichia coli dUTPase as

167 ine was determined to 2.18 A resolution with molecular replacement using rat PITPalpha (77% sequence

168 The structure was solved by molecular replacement using rat serum mannose-binding pr

169 The structural solution was obtained by molecular replacement using superimposed polyalanine coo

170 structure determined to 2.0 A resolution by molecular replacement using the coordinates of a truncat

171 The structure was solved by molecular replacement using the coordinates of the isomo

172 The structure was solved by molecular replacement using the crystal structure of a m

173 The structure was solved by molecular replacement using the crystal structure of the

174 re obtained, and the structure was solved by molecular replacement using the CsdB coordinates combine

175 at 1.85 A (cubic), respectively, resolved by molecular replacement using the homologous avian infecti

176 m) was determined to a resolution of 2.7A by molecular replacement using the human apo-N-lobe and the

177 murium have been determined by the method of molecular replacement using the known structure of the h

178 the presence of 0.1 M Mg(2+), was solved by molecular replacement using the model of cowpea chloroti

179 se from Bacillus subtilis, was determined by molecular replacement using the muconate lactonizing enz

180 eductase superfamily, has been determined by molecular replacement using the NADPH-bound form of the

181 f the PLP-bound holoenzyme was determined by molecular replacement using the Pseudomonas fluorescens

182 l structure of human sfALR was determined by molecular replacement using the rat sfALR structure.

183 The native structure was solved by molecular replacement using the structure of the homolog

184 C was also determined to 2.9 A resolution by molecular replacement using the TbODC DFMO-bound structu

185 The crystal structure was solved by molecular replacement using the unliganded structure and

186 alpha was determined at 2.3 A resolution by molecular replacement using the wild-type V alpha struct

187 r has been determined to 2.1 A resolution by molecular replacement using truncated mouse ODC (Delta42

188 2-phosphoglycolate (PGL), was determined by molecular replacement using X-ray diffraction data to 2.

189 bitor (K(d) = 0.4 microM) were determined by molecular replacement using X-ray diffraction data to 2.

190 The structure was solved by molecular replacement, using a composite of the parent s

191 Phases were obtained by molecular replacement, using our previously determined r

192 ly, ResQ B-factor profile was used to assist molecular replacement, which resulted in successful solu

193 9-9.0 A) was analyzed using a combination of molecular replacement with an energy-minimized model and

194 AD+(gamma) was solved to 2.7 A resolution by molecular replacement with human class I beta1 beta1 ADH

195 , in fact, a bound Na ion as demonstrated by molecular replacement with Rb+.

196 Molecular replacement with the E.coli DnaK(SBD) model wa

197 merization site, and its structure solved by molecular replacement with the model of fragment D.

198 The initial phasing was done by molecular replacement with the mouse ODC structure.

199 The structure was solved by molecular replacement with the Pseudomonas aeruginosa ca

200 Using data to 2.8 A resolution and molecular replacement with the refined model of the carb

201 that has been solved to 3.1 A resolution by molecular replacement with the structure of a dual funct

202 Molecular replacement with the Thermotoga maritima NifS

203 vative of the native protein, and then using molecular replacement with the unrefined structure as a

204 ns that reach the high accuracy required for molecular replacement without any experimental phase inf