ライフサイエンスコーパス: molecularly

1 pecies that can be identified genetically or molecularly.

2 stem cells that have yet to be characterized molecularly.

3 is, and subsequent epidermal hyperplasia and molecularly abolished TGF-beta and NF-kappaB activation.

4 However, how this is molecularly achieved remains largely unresolved.

5 e surface which belong to dissociatively and molecularly adsorbed water molecules, based on theoretic

6 By molecularly aligning the hydrophobic chromophores along

7 We believe that, since molecularly alike tumors could respond similarly to trea

8 era of precision medicine, where DCIS can be molecularly analyzed by tools, such as next-generation D

9 ia from different nervous system regions are molecularly and anatomically distinct, but whether they

10 ysregulation is a common mechanism shared by molecularly and clinically heterogenous neurodegenerativ

11 Venous endothelial cells are molecularly and functionally distinct from their arteria

12 ift our focus towards viewing fibroblasts as molecularly and functionally heterogeneous and provides

13 ed aged OPCs cultured on these scaffolds are molecularly and functionally rejuvenated.

14 Induced trophoblast stem cells are molecularly and functionally similar to trophoblast stem

15 ug response, which provide rich resources of molecularly and pharmacologically profiled cancer sample

16 It is a molecularly and phenotypically highly heterogeneous dise

17 We identified two molecularly and projection-specified subpopulations of L

18 ease-causing mutations in the NHL domain are molecularly and structurally conserved between fly and h

19 ext-specific responses that can be dissected molecularly and used for phenotypic benefit in brain dis

20 Collectively, our data identify two molecularly- and projection-specified subpopulations of

21 ns, thus providing a unique patient-derived, molecularly annotated pharmacologic resource that is ref

22 red ESBL-producing E. coli strains qualified molecularly as pathogens.

23 There is a need for a more refined, molecularly based classification model for glioblastoma

24 l Trial (MOT), which hybridizes the power of molecularly based master interventional protocols with t

25 al nanobiosensor was invented based on a new molecularly bioimprinted siloxane polymer (MBIS) strateg

26 Here, we molecularly characterize human SSCs and define condition

27 We set out to molecularly characterize LELC-B through RNA expression p

28 The aim of this study was to molecularly characterize the effects of C/EBPepsilon tra

29 In this study, we aimed to molecularly characterize the first family with a dominan

30 In this study, we produced and molecularly characterized a specific monoclonal anti-IL1

31 its performance at predicting genes for both molecularly characterized and uncharacterized diseases i

32 NMC is molecularly characterized by chromosomal rearrangement o

33 DDLPS is molecularly characterized by wild-type p53 and amplifica

34 experiments from 910 combinations across 85 molecularly characterized cancer cell lines, and results

35 et al. report on the largest clinically and molecularly characterized cohort of pediatric low-grade

36 e-of-the-art methods at predicting genes for molecularly characterized diseases by 14%-65%.

37 ly successful at increasing our knowledge of molecularly characterized diseases.

38 on blood cultures spiked with 185 different molecularly characterized Enterobacterales isolates.

39 In a large cohort of molecularly characterized inherited retinal disease (IRD

40 Here we molecularly characterized neurons in the mouse superfici

41 cer are poorly understood owing to a lack of molecularly characterized patient cohorts with long-term

42 have not been comprehensively classified or molecularly characterized.

43 Using molecularly classified patient-derived xenograft (PDX) l

44 t and develop a machine learning approach to molecularly classify and characterize tumour-immune phen

45 Molecularly cloned SIVmac239 is difficult for antibodies

46 with one drug, may be optimized by treating molecularly complex and heterogeneous cancers with combi

47 A total of 199 patients and 326 eyes with molecularly confirmed (ABCA4) STGD1 underwent testing wi

48 Patients with molecularly confirmed BVMD were compared with normal con

49 A total of 29 patients with molecularly confirmed L-ORD were included in this prospe

50 om a cross sectional survey of families with molecularly confirmed LS.

51 Fifteen patients with molecularly confirmed PDE were detected using liquid chr

52 al and auditory symptoms in (i) 56 biallelic molecularly confirmed USH2A patients and (ii) ush2a muta

53 All patients with molecularly confirmed vEDS were included in a retrospect

54 tients (mean age, 20 years; range 9-40) with molecularly confirmed XLRS were included.

55 phy (OCT) in a large cohort of patients with molecularly-confirmed, ABCA4-associated Stargardt diseas

56 innervation, how it is initiated, and how it molecularly contributes to disease.

57 tic and environmental insults, many of which molecularly converge on transcriptional dysregulation, r

58 Molecularly, Crabp1 acts as a novel atRA-inducible scaff

59 The integration of molecularly crowded microenvironments into membrane-encl

60 ation that occurs in structurally organized, molecularly crowded, and dimensionally constrained amphi

61 We sought to characterize molecularly cutaneous inflammation and its correlation w

62 nt-derived systemic approach to identify and molecularly define progestin and adipoQ receptor family

63 utathione metabolism, providing an alternate molecularly defined biomarker for this drug.

64 Within molecularly defined cerebellar modules we found spatial

65 in a prospective cohort of 42 patients with molecularly defined gastrointestinal cancers and acquire

66 roblast growth factor FGF21 was labeled with molecularly defined gold nanoparticles (AuNPs), applied

67 h ponatinib as a treatment strategy for this molecularly defined group of patients.

68 In contrast, here, we report a molecularly defined manganese catalyst that allows for l

69 for manipulating the electronic structure of molecularly defined materials.

70 The PVH uses combinatorial assemblies of molecularly defined neuron populations for grouped-ensem

71 Our results show that molecularly defined neurons are important processing uni

72 We propose that certain molecularly defined pathways within the reward circuitry

73 Our results reveal the existence of molecularly defined phenotypes associated with outcome i

74 In vivo calcium imaging revealed that molecularly defined RGCs exhibit specific functional tun

75 nization mass spectrometry (ESI-MS) to study molecularly defined SACs supported on polyoxometalates i

76 HDAC1/HDAC2 and MYC may present a novel and molecularly defined strategy to target mutant p53 in pan

77 d substrates with high spatial precision and molecularly defined structure is essential to interface

78 an opportunity to re-classify patients into molecularly defined subgroups that better reflect underl

79 neurons at single-cell resolution and links molecularly defined subnetworks to the functional organi

80 utic strategies may offer a benefit for this molecularly defined subpopulation.

81 ious challenges may drive AML progression in molecularly defined subsets and identify RTK inhibition

82 wed high activity in newly diagnosed AML and molecularly defined subsets of relapsed or refractory AM

83 They divide NKTCL into molecularly defined subtypes that could inform therapeut

84 disease prognostic, and closely linked with molecularly defined subtypes.

85 ription factor-mediated differentiation in a molecularly defined system.

86 We also molecularly defined the development of Sertoli, Leydig a

87 der and higher-order thalamic nuclei to form molecularly defined TRN-thalamus subnetworks.

88 The catalyst is molecularly defined, is phosphine-free, and can operate

89 hods have been successfully used to identify molecularly-defined disease subtypes.

90 a path to organic, biofunctionalized, fully molecularly-defined electrodes for neuronal applications

91 st multiple, complex potential roles for the molecularly-defined, CRH-dependent circuit in modulation

92 s of persistent viral DNA in NHPs.IMPORTANCE Molecularly defining the viral reservoir that persists d

93 reater odds (95% CI 3.85-6.84; P < 0.001) of molecularly detected infections (from the published lite

94 These accounted for 71.8% of all molecularly diagnosed families.

95 of ill-defined composition, and is caused by molecularly different and often rare diseases that occur

96 le negative breast cancer (TNBC) encompasses molecularly different subgroups, with a subgroup harbori

97 ssue within the tumour, and hence mapping of molecularly different tumour regions in 3D space.

98 ment with the establishment of spatially and molecularly discrete progenitor domains that give rise t

99 technology that serves as a tunable site to molecularly dissect metastatic disease mechanisms.

100 Here, we uncover molecularly dissociable roles for nucleosome remodeler I

101 on-covalent assembly exists exclusively in a molecularly dissolved state.

102 elative to that achieved using solution-cast molecularly-dissolved copolymer chains.

103 This analysis identified two molecularly distinct AKI subphenotypes with different cl

104 ity of a single antibody to bind to multiple molecularly distinct antigens and is a common feature of

105 f acute viral and bacterial infections and a molecularly distinct Blimp1(lo)Id3(hi) tissue-resident m

106 y can be achieved through parallelization of molecularly distinct but functionally overlapping pathwa

107 RNA-seq) approach to systematically classify molecularly distinct cell populations in the mouse VPH.

108 pproach to develop a comprehensive census of molecularly distinct cell types in the mouse LHA.

109 We conclude that axon guidance cues, not molecularly distinct dendritic arbors, are a major deter

110 arized cells organized into functionally and molecularly distinct domains.

111 Macrophages at the nerve crush site are molecularly distinct from macrophages associated with Wa

112 Thus, these molecularly distinct GSC lines recapitulated the subpopu

113 neurons trigger two spatially segregated and molecularly distinct induction mechanisms that lead to t

114 These molecularly distinct LHA Nts subpopulations also differ

115 ght to occur via at least two temporally and molecularly distinct mechanisms, which lead to short-ter

116 centriole during mitosis, thereby generating molecularly distinct mother and daughter centrioles befo

117 xposes transcriptomic evidence for dozens of molecularly distinct neuropeptidergic modulatory network

118 Cortical layer 1 (L1) contains a sparse and molecularly distinct population of inhibitory interneuro

119 lyses of these markers reveal at least three molecularly distinct proprioceptor subtypes.

120 trate that epithelia are capable of mounting molecularly distinct responses to loss of different spin

121 ar synaptic specificity could be achieved by molecularly distinct subcellular domains that locally re

122 r show that P2ry1-Pet1 DR neurons - the most molecularly distinct subtype - possess unique efferent p

123 ain-derived neurotrophic factor release from molecularly distinct vHC-PrL projection neurons modulate

124 ution method to dissect complex tissues into molecularly distinctive tissue or cell subtypes based on

125 d proteins, and the quantitative function of molecularly diverse mutants, competitively with the stat

126 he circadian clock uses circuit-specific and molecularly diverse output pathways to enhance the abili

127 ta, suggesting that quantitative analysis of molecularly diverse sparsely-distributed features may be

128 Rapidly evolving and molecularly diverse, they derive from multiple male secr

129 focusing more on disease biology and robust molecularly driven patient stratification in future clin

130 A next step is to identify molecularly driven phenotypes using "omics" technologies

131 ive sulfation route based on an inexpensive, molecularly efficient and solubilising cation exchanging

132 ,467 patients that were screened, 2,007 were molecularly eligible for entry into the trial, and 302 e

133 when assuming that all cells in a tissue are molecularly equivalent, we predict a common ("universal"

134 mechanisms has made it possible to formulate molecularly explicit mathematical models that reproduce

135 Here we present a molecularly explicit simulation of constricting partiall

136 0 000 episodes of respiratory illness tested molecularly for multiple respiratory viruses between 200

137 Molecularly, Foxp1 directly represses beta3-AR transcrip

138 r results strongly support the hypothesis of molecularly, functionally, and spatially distinct subdom

139 nting a 'penumbra', which slowly succumbs to molecularly governed spatial cellular stoichiometric rel

140 in patients with pancreatic cancer, and that molecularly guided treatments targeting oncogenic driver

141 ly restricted excitatory modules composed of molecularly heterogeneous cell types.

142 As fibrotic diseases are often molecularly heterogeneous, molecular imaging of a specif

143 erent parts of the tongue that are otherwise molecularly heterogeneous.

144 By comparing Ca(2+) activity of the molecularly homogeneous PFC->PAG type against two hetero

145 tal interneuron type in primates that had no molecularly homologous counterpart in mice or ferrets.

146 Molecularly, HSCs carrying dysfunctional mitochondria ca

147 AB and three yeast strains were selected and molecularly identified.

148 We now used a genome-wide siRNA screen to molecularly identify the widely expressed acid-sensitive

149 to increase the sensitivity of detection of molecularly imprinted conductive polymer-coated electrod

150 Here, we report the synthesis of a molecularly imprinted nanocarrier using hydrothermal pro

151 Soft molecularly imprinted nanogels (nanoMIPs), selective for

152 Therefore, soft molecularly imprinted nanogels that obey to analyte-indu

153 on of 100.0 mL of sample through 200.0 mg of molecularly imprinted poly(vinylimidazole-TRIM) (MIP-1VN

154 Magnetic dual-template molecularly imprinted polymer (Fe(3)O(4)@SiO(2)-MDMIP) w

155 w composite comprising of ionic liquid-based molecularly imprinted polymer (MIP) and gold nanoparticl

156 d for IXC, based on environmentally friendly molecularly imprinted polymer (MIP) coated on silica-car

157 Here, we developed a molecularly imprinted polymer (MIP) electrode for the de

158 The "gate effect" mechanism for conductive molecularly imprinted polymer (MIP) film coated electrod

159 Numerous conducting molecularly imprinted polymer (MIP) films are deposited

160 A molecularly imprinted polymer (MIP) recognition system w

161 The optimum synthesized core-shell molecularly imprinted polymer (MIP) was applied as a sor

162 hexagonal boron nitride (HBN) nanosheets and molecularly imprinted polymer (MIP) was presented for et

163 A highly selective and sensitive molecularly imprinted polymer (MIP)-based electrochemica

164 the performance of a new magnetic assay with molecularly imprinted polymer (MIP)-based ELISA for the

165 This research aims to engineer molecularly imprinted polymer (MIP)-based synthetic rece

166 A novel magnetic molecularly imprinted polymer (MMIP) for the preconcentr

167 al fluorophores, and a mesoporous structured molecularly imprinted polymer as a receptor (B/YCDs@mMIP

168 The components of the molecularly imprinted polymer nanoparticle assay (MINA)

169 ighly specific sensor based on electroactive molecularly imprinted polymer nanoparticles (nanoMIP) wa

170 Recently, a molecularly imprinted polymer nanoparticles (nanoMIPs) -

171 es and enzymes are replaced with fluorescent molecularly imprinted polymer nanoparticles (nanoMIPs) a

172 A molecularly imprinted polymer nanoparticles modified ele

173 ork, we report the synthesis of a mesoporous molecularly imprinted polymer on the surface of silica n

174 thod relies on the application of an in-line molecularly imprinted polymer solid-phase extraction mic

175 A novel molecularly imprinted polymer-capped acrylated nitrogen

176 developed using gold nanoparticles-decorated molecularly imprinted polymers (AuNP-MIPs).

177 The lab-made molecularly imprinted polymers (MIP), selective for simp

178 Molecularly imprinted polymers (MIPs) are tailor-made ch

179 compatible with intra-body applications with molecularly imprinted polymers (MIPs) as recognition ele

180 Molecularly imprinted polymers (MIPs) emerged thanks to

181 in an optical sensor after modification with molecularly imprinted polymers (MIPs) for determination

182 challenge, electrochemical sensing based on molecularly imprinted polymers (MIPs) has become an inte

183 Molecularly imprinted polymers (MIPs) have been develope

184 lternatives to natural receptors, artificial molecularly imprinted polymers (MIPs) have received grea

185 Highly selective molecularly imprinted polymers (MIPs) towards benzyl met

186 The aim of this study was to prepare molecularly imprinted polymers (MIPs) with ampicillin (A

187 We here report on molecularly imprinted polymers (MIPs) with an external p

188 Conditions for preparation of molecularly imprinted polymers (MIPs), adsorption perfor

189 ive extraction of rosmarinic acid (RA) using molecularly imprinted polymers (MIPs).

190 provided by the use of bioinspired anti-FLAG molecularly imprinted polymers (MIPs).

191 rates the feasibility of such a device using molecularly imprinted polymers (MIPs).

192 tal-organic framework deep eutectic solvents/molecularly imprinted polymers (MOF- DES/MIPs) and were

193 Molecularly imprinted polymers are synthetic receptors f

194 ation is crucial for the characterization of molecularly imprinted polymers, especially if biological

195 particles with antibody-like affinity, i.e., molecularly imprinted polymers, offer an ideal platform

196 , immunoassays and DNA analysis, cytosensor, molecularly imprinted sensors, ECL resonance energy tran

197 Herein we describe the preparation of molecularly imprinted silica nanoparticles by Ostwald ri

198 Molecularly imprinted sol-gel polymers (MIS) specific to

199 Afterwards, the method of core-shell molecularly imprinted solid phase extraction (CSMISPE) w

200 An optimized molecularly imprinted solid phase extraction (MISPE) pro

201 The development of a novel molecularly imprinted solid-phase extraction (MISPE) met

202 work reports the innovative combination of a molecularly-imprinted polymer (MIP) and a natural antibo

203 A molecularly-imprinted polymer (MIP) was produced at the

204 ophene) (PEDOT) layer and a polypyrrol (PPy) molecularly-imprinted polymer (MIP), assembled in-situ.

205 hylenedioxythiophene) (PEDOT) layer, using a molecularly-imprinted polymer of polypyrrol (PPy) as bio

206 h AP complexes, we find that they define two molecularly independent pathways: While EPSIN1 associate

207 city and minute resolution of FLiCRE enables molecularly informed characterization, manipulation, and

208 ss towards the deployment of more effective, molecularly informed treatments for affected patients.

209 We searched for factors genetically or molecularly interacting with the p21-activating kinase h

210 lly emerges and how its downstream fates are molecularly interconnected remain unknown.

211 and its prevalence, as defined molecularly, is higher than previously reported.

212 Metastasis is a molecularly late event, and immunosuppression driven by

213 s outside of northeastern Massachusetts were molecularly linked to the outbreak.

214 nable molecular alterations and who received molecularly matched therapy had a longer median overall

215 al than similar patients who did not receive molecularly matched therapy.

216 ymer-fullerene domains to consisting of both molecularly mixed and fullerene domains.

217 Overall, the molecularly mixed composite membrane provide significant

218 formation or agglomeration, creating unique, molecularly mixed composite membranes.

219 her blends (with low offset or predominantly molecularly mixed domains), nanosecond geminate electron

220 lm structures were varied from consisting of molecularly mixed polymer-fullerene domains to consistin

221 Here, we show that in larval zebrafish, molecularly, morphologically and electrophysiologically

222 In conclusion, SINs represent a molecularly, morphologically, and functionally heterogen

223 to freeload from the protection provided by molecularly orthologous defenses from another species.

224 The structural and electronic properties of molecularly pillared graphene sheets were explored by pe

225 ent connectivity, structural regularity, and molecularly precise porosity.

226 , has enabled the design and construction of molecularly-precise objects for a myriad of applications

227 pplied the system to detect dengue fever and molecularly profile cancer cells through multi-channel p

228 gen-mimetic peptides (CMPs), are employed as molecularly programmable crystallizable units.

229 port phagosomal and endosomal NO, and can be molecularly programmed to display precise stoichiometrie

230 In a molecularly related B-cell malignant tumor (classic Hodg

231 The spotted regions were molecularly resolved from the supporting mouse brain tis

232 s in mice, the in vivo corona is found to be molecularly richer in comparison to its counterpart ex v

233 t be challenging due to the size mismatch of molecularly scaled reactive functional groups and nanosc

234 as immunomodulatory agents in appropriately molecularly selected populations.

235 layer but is largely excluded from otherwise molecularly similar neurons in the inner retina.

236 ugh endocardial and vascular endothelium are molecularly similar, endocardial endothelial cells exhib

237 Molecularly sized pores significantly enhance the associ

238 The operando NMR spectra provide molecularly specific, time-resolved information about th

239 Non-invasive, molecularly-specific, focal modulation of brain circuits

240 lidation to feed into the next generation of molecularly stratified clinical trials.

241 The number of molecularly stratified treatment options available to pa

242 These findings can be applied to molecularly stratify patients, explain improved outcomes

243 ly available multi-omic profiling to provide molecularly tailored therapy options and clinical trial

244 al tool for both researchers and surgeons to molecularly target a variety of biological tissues and p

245 bines a cytotoxic radioactive isotope with a molecularly targeted agent to produce an anticancer ther

246 h as chemotherapeutics and radiation), novel molecularly targeted agents and immune-checkpoint inhibi

247 In the past decade, the introduction of molecularly targeted agents and immune-checkpoint inhibi

248 cancer using new combination designs such as molecularly targeted agents, including histone deacetyla

249 ir use for the encapsulation of low-toxicity molecularly targeted anticancer agents has been limited.

250 remarkable clinical efficacy demonstrated by molecularly targeted cancer therapeutics, the benefits a

251 ATP hydrolysis site, has shown promise as a molecularly targeted cancer therapy.

252 as a paradigm for successful application of molecularly targeted cancer therapy.

253 There has also been a push to develop new molecularly targeted contrast agents or agents that can

254 The effects of molecularly targeted drug perturbations on cellular acti

255 SOCS function could be exploited to develop molecularly targeted drugs with unique modes of action t

256 ology hinges on linking tumour genotype with molecularly targeted drugs(1); however, targeting the fr

257 rabilities that clinicians can exploit using molecularly targeted drugs, guided by knowledge of the t

258 amic pharmacogenomic associations against 37 molecularly targeted drugs.

259 ds known as aptamers or chemical antibodies, molecularly targeted exosomes are poised to become the n

260 Noninvasive molecularly targeted imaging may play a critical role in

261 nose bacterial infections when paired with a molecularly targeted infection imaging agent.

262 Although molecularly targeted optical contrast agents can be used

263 results confirm the potential of CR3022 as a molecularly targeted probe for SARS-CoV-2.

264 Molecularly targeted radionuclides have great potential

265 Here, we explore the use of CR3022 as a molecularly targeted radiotherapeutic.

266 The advent of molecularly targeted therapeutic agents has opened a new

267 on altered signaling pathways as a basis for molecularly targeted therapeutic strategies are still sp

268 Molecularly targeted therapeutics have had limited effic

269 ntial use in clinical cancer diagnostics and molecularly targeted therapeutics.

270 lopment of combinations of immunotherapy and molecularly targeted therapies for metastatic breast can

271 Here we discuss the implications of how molecularly targeted therapies in solid malignancies tha

272 Resistance to chemotherapy and molecularly targeted therapies is a major problem in cur

273 ehensive genomic profiling, incorporation of molecularly targeted therapies is another area of active

274 Optimal integration of molecularly targeted therapies, such as tyrosine kinase

275 l alterations have led to the development of molecularly targeted therapies, whose efficacy has been

276 allows for rapid adaptation to cytotoxic or molecularly targeted therapy and could create a form of

277 ecently developed a synthetic microRNA-based molecularly targeted therapy for improving HCC response

278 l heterogeneity underlies tumour escape from molecularly targeted therapy in glioblastoma.

279 These results extend the benefits of molecularly targeted therapy to the entire spectrum of p

280 representing the most successful advance in molecularly targeted therapy.

281 cation of ever-smaller patient subgroups for molecularly targeted therapy.

282 er understand GA pathogenesis and evaluate a molecularly targeted treatment approach for this disease

283 We have identified potential candidates for molecularly targeted treatment strategies that will need

284 ch can be inhibited with ispinesib, a potent molecularly-targeted drug.

285 We show, molecularly, that the interaction of the 6B strain with

286 Molecularly, the specific HR protein Rad51 was severely

287 A molecularly thin layer of 2-aminobenzenethiol (2-ABT) wa

288 Field effect transistors fabricated on molecularly thin Ruddlesden-Popper perovskite using grap

289 nstrate a materials platform for complex and molecularly thin superlattices, devices and integrated c

290 rbed, or histidine-modified peptides, such a molecularly tunable system based on a surface-imprinting

291 throughout the cell cycle, and how they are molecularly tuned, remain unknown.

292 able to accurately predict disease genes for molecularly uncharacterized diseases.

293 e additional alleles of sup-45, a previously molecularly uncharacterized genetic locus.

294 logic plasticity in many senses without ever molecularly undoing the specific mapping of an entire pr

295 somal-dominant Robinow syndrome cases remain molecularly unsolved.

296 Molecularly, upregulation of Ral GTPase activity and Sox

297 demonstrated that teratomas can be sculpted molecularly via microRNA (miRNA)-regulated suicide gene

298 Molecularly, we propose that MLL-AF9 preserves gene expr

299 Molecularly, we show that KDM5 activates the expression

300 The layered two-dimensional molecularly woven material has long-range order, is bire