ライフサイエンスコーパス: moloney

1 genus Nannomys, are susceptible to ecotropic Moloney and Friend mouse leukemia viruses (MLVs) but not

2 Ordered arrays of histidine-tagged Moloney capsid protein (his-MoCA) were obtained on membr

3 M. spicilegus neonates were inoculated with Moloney ecotropic MLV (MoMLV).

4 ype 1 enzyme and from +1 to +7 or +8 for the Moloney enzyme.

5 Remarkably, although Moloney leukemia virus (MLV) assembles in the cytoplasm,

6 ch repair of retroviral double-stranded DNA, Moloney leukemia virus (MLV)-based vectors with a mutati

7 Moloney leukemia virus 10 (MOV10) protein is a superfami

8 d others reported that ectopic expression of Moloney leukemia virus 10 (MOV10) protein strongly inhib

9 As through its interaction with RNA helicase Moloney leukemia virus 10 (MOV10).

10 Moloney leukemia virus 10, homolog (MOV10) is an IFN-ind

11 Dnmt3b during de novo methylation of murine Moloney leukemia virus provirus DNA in virus-infected ES

12 T is different from the basic loop of either Moloney leukemia virus RNase H or Escherichia coli RNase

13 Moloney leukemia virus type 10 protein (MOV10) is an RNA

14 This system includes a murine Moloney leukemia virus vector which contains a neomycin

15 ls also stimulated infection by amphotrophic Moloney leukemia virus, herpes simplex virus, and viruse

16 A Moloney leukemia virus-based retroviral system was set u

17 ivo transduction and expansion, and standard Moloney leukemia virus-based retroviral vectors.

18 rom a recombination between gag sequences in Moloney MLV (Mo-MLV) and the c-abl proto-oncogene.

19 ble with LacZ pseudotypes having AKV Env and Moloney MLV (MoMLV) Gag proteins, further indicating tha

20 unctional genes, we inoculated neonates with Moloney MLV (MoMLV) or amphotropic MLV (A-MLV) and scree

21 The T-cell disease specificity of Moloney MLV also appeared to correlate with the affinity

22 predominant phosphorylated viral protein of Moloney MLV and is required for virus viability.

23 nge at position 8 (H8R) in the SPHQ motif of Moloney MLV blocks infection by arresting virus-cell fus

24 ne change at position 84 (D84K) of ecotropic Moloney MLV Env abolishes virus binding and infection.

25 iphasic response that differentiated between Moloney MLV Env and VSV G at low concentrations, at whic

26 gave comparable dose-dependent inhibition of Moloney MLV Env and VSV G pseudotypes, suggesting that t

27 ore MLV particles versus effects specific to Moloney MLV envelope protein (Env).

28 Moloney MLV infection was lower on cathepsin B knockout

29 ification of large quantities of recombinant Moloney MLV NC protein, and have studied its interaction

30 se results establish that membrane fusion of Moloney MLV occurs via a hemifusion intermediate.

31 activates chromatin binding in the wild-type Moloney MLV p12 protein.

32 (KO) and wild-type (WT) mice with Friend or Moloney MLV P50-deficient viruses, we found that APOBEC3

33 Analysis of known Moloney MLV target genes in these lymphomas showed a hig

34 fection of NIH 3T3 cells, endocytosis brings Moloney MLV to early lysosomes, where the virus encounte

35 1 and PREP1 are cellular factors involved in Moloney MLV transcription regulation.

36 ection could be enhanced by preincubation of Moloney MLV with cathepsin B, consistent with SU cleavag

37 x2 mice with Moloney murine leukaemia virus (Moloney MLV) also led to a dramatic acceleration of tumo

38 e site in the Moloney murine leukemia virus (Moloney MLV) enhancer was previously shown to be an impo

39 The neurovirulent retroviruses FrCasE and Moloney MLV-ts1 cause noninflammatory spongiform neurode

40 spicilegus mouse neonatally inoculated with Moloney MLV.

41 ts of several murine retroviruses, including Moloney MLV.

42 in determining the pathogenic properties of Moloney MLV.

43 We developed a Moloney mouse leukemia virus (MLV)-based retroviral repl

44 on has been unclear, since gPr80gag-negative Moloney MuLV (M-MuLV) mutants are replication competent

45 ominantly with a single group of proviruses, Moloney MuLV (M-MuLV) recombines with at least two disti

46 The enhancer elements of the Moloney MuLV (M-MuLV) were replaced by the 170-bp enhanc

47 laced by equivalent sequences from ecotropic Moloney MuLV (M-MuLV).

48 nction, suggesting a role for this region in Moloney MuLV assembly.

49 In this study, gly-491 of Moloney MuLV Env has been replaced with other residues a

50 ed protein for a glycine residue (gly-491 in Moloney MuLV Env) that is otherwise conserved in all of

51 t interact with the reverse transcriptase of Moloney MuLV resulted in the identification of eRF1, the

52 previously generated between the ecotropic (Moloney-MuLV) and amphotropic (4070A) SU and TM proteins

53 Neonatal infection of CD2-Runx2 mice with Moloney murine leukaemia virus (Moloney MLV) also led to

54 iring within the Psi-RNA packaging signal of Moloney murine leukaemia virus (MoMuLV) expose conserved

55 B-lymphoma Moloney murine leukaemia virus insertion region-1 (BMI1)

56 show that, unlike classical chaperones, the Moloney murine leukaemia virus NC uses a unique mechanis

57 ar reporter genes were delivered into ECs by Moloney murine leukaemia virus or human immunodeficiency

58 Pan proviral insertion site of Moloney murine leukemia (PIM) 1, 2, and 3 kinase inhibit

59 rgeting motifs (TVTMs) within the context of Moloney murine leukemia envelope "escort" proteins.

60 Cotransfection of RPL4 cDNA with Moloney murine leukemia proviral DNA results in Gag proc

61 e greater than those generated by a standard Moloney murine leukemia retroviral vector, and they were

62 We investigated the utility of the Moloney murine leukemia retrovirus (MLV) pseudotyped wit

63 n adult floxed mice by a vector based on the Moloney murine leukemia retrovirus, expressing Cre recom

64 specific binding to avian myeloblastosis or Moloney murine leukemia RTs was detected.

65 dimerization domain in genomes isolated from Moloney murine leukemia virions using a quantitative and

66 nal structure of the double hairpin from the Moloney murine leukemia virus ([Psi(CD)](2), 132 nt, 42.

67 Moloney murine leukemia virus (M-MLV) replication is res

68 mbinant avian myeloblastosis virus (AMV) and Moloney murine leukemia virus (M-MLV) reverse transcript

69 In the case of the ecotropic Moloney murine leukemia virus (M-MLV), the Nef-like effe

70 substrates and the reverse transcriptases of Moloney murine leukemia virus (M-MuLV) and human immunod

71 t structural studies have suggested that the Moloney murine leukemia virus (M-MuLV) CA protein may as

72 ly stained, membrane-bound, histidine-tagged Moloney murine leukemia virus (M-MuLV) capsid protein (h

73 s shown that gPr80gag facilitates release of Moloney murine leukemia virus (M-MuLV) from cells along

74 The p12 region of the Moloney murine leukemia virus (M-MuLV) Gag protein conta

75 The nature of Moloney murine leukemia virus (M-MuLV) infection after a

76 wo-end integration reaction catalyzed by the Moloney murine leukemia virus (M-MuLV) integrase (IN) wa

77 Moloney murine leukemia virus (M-MuLV) is a replication-

78 Moloney murine leukemia virus (M-MuLV) is a replication-

79 nces within terminal inverted repeats of the Moloney murine leukemia virus (M-MuLV) LTR were synthesi

80 system that mimics the assembly of immature Moloney murine leukemia virus (M-MuLV) particles to exam

81 were generated within the 3' terminus of the Moloney murine leukemia virus (M-MuLV) pol gene encoding

82 The matrix protein (MA) of the Moloney murine leukemia virus (M-MuLV) was found to inte

83 an immunodeficiency virus type 1 (HIV-1) and Moloney murine leukemia virus (M-MuLV) were shown to req

84 as constructed by replacing the U3 region of Moloney murine leukemia virus (M-MuLV) with homologous s

85 n immunodeficiency virus, type 1 (HIV-1) and Moloney murine leukemia virus (M-MuLV), we determined th

86 -1 (human immunodeficiency virus type 1) and Moloney murine leukemia virus (M-MuLV), we evaluated how

87 Early bone marrow infection of Moloney murine leukemia virus (M-MuLV)-infected mice was

88 mmunodeficiency virus type 1 (HIV-1) and the Moloney murine leukemia virus (M-MuLV).

89 of the Gag protein p12 block replication of Moloney murine leukemia virus (M-MuLV).

90 we have infected v-Myb transgenic mice with Moloney murine leukemia virus (M-MuLV).

91 Using Moloney murine leukemia virus (MLV) as a tool, we examin

92 cently discovered that the NC protein of the Moloney murine leukemia virus (MLV) can bind with high a

93 We have generated Moloney murine leukemia virus (MLV) envelope derivatives

94 nalyze more than 40 derivatives of ecotropic Moloney murine leukemia virus (MLV) envelope, containing

95 ion of psi (i.e., leader) sequences from the Moloney murine leukemia virus (MLV) genome into the 3' u

96 racterized the structure and function of the Moloney murine leukemia virus (MLV) IN protein in viral

97 identified as a common integration site for Moloney murine leukemia virus (MLV) in rat thymic lympho

98 The roles of cellular proteases in Moloney murine leukemia virus (MLV) infection were inves

99 ansportin 3 protein under conditions whereby Moloney murine leukemia virus (MLV) integrase failed to

100 Moloney murine leukemia virus (MLV) particles contain bo

101 linkages, we digested deproteinized RNA from Moloney murine leukemia virus (MLV) particles with RNase

102 The Moloney murine leukemia virus (MLV) repressor binding si

103 n HIV-1-based lentiviral vector to that by a Moloney murine leukemia virus (MLV) retroviral vector, u

104 ups of synthetic RNA-DNA hybrids with either Moloney murine leukemia virus (MLV) RT or human immunode

105 Moloney murine leukemia virus (MLV) selectively encapsid

106 mmaretroviruses, we engineered a fluorescent Moloney murine leukemia virus (MLV) system consisting of

107 purvalanol A, and methoxy-roscovitine, block Moloney murine leukemia virus (MLV) transcription events

108 mo- and heterodimerization were examined for Moloney murine leukemia virus (MLV) using nondenaturing

109 f human hematopoietic stem cells (HSCs) with Moloney murine leukemia virus (MLV) vectors have been an

110 vity, while infection by the gammaretrovirus Moloney murine leukemia virus (MLV) was unaffected.

111 escribe the properties of the Gag protein of Moloney murine leukemia virus (MLV), a gammaretrovirus.

112 n, with functionally homologous regions from Moloney murine leukemia virus (MLV), a murine retrovirus

113 ins from four different retroviruses: HIV-1, Moloney murine leukemia virus (MLV), Rous sarcoma virus

114 file that may be safer than that of standard Moloney murine leukemia virus (MLV)-derived retroviral v

115 nd Mason-Pfizer monkey virus (M-PMV) but not Moloney murine leukemia virus (MLV).

116 lls are unable to support the replication of Moloney murine leukemia virus (MLV).

117 APOBEC3 (mA3) and human APOBEC3G (hA3G) upon Moloney murine leukemia virus (MLV).

118 retroviral promoters and enhancers from the Moloney Murine Leukemia Virus (MMLV) and the Myeloprolif

119 An RNA kissing loop from the Moloney murine leukemia virus (MMLV) exhibits unusual me

120 Encapsidation of the Moloney murine leukemia virus (MMLV) genome is mediated

121 ed to play a similar preintegrative role for Moloney murine leukemia virus (MMLV) in addition to HIV-

122 ies of the 3' end processing site within the Moloney murine leukemia virus (MMLV) LTR d(TCTTTCATT), a

123 (RT) fidelity, we measured the error rate of Moloney murine leukemia virus (MMLV) RT in the presence

124 s in the pE vectors have been taken from the Moloney murine leukemia virus (MMLV) vector pMFG, which

125 ocytes are refractory to gene transfer using Moloney murine leukemia virus (MMLV)-based retroviral ve

126 ansplantation model, the authors evaluated a Moloney murine leukemia virus (MMLV)-based vector encodi

127 In this report, we made use of a chimeric Moloney murine leukemia virus (MMLV)-HIV-1 Gag in which

128 rely upon the template switching property of Moloney murine leukemia virus (MMLV)-type reverse transc

129 n JSRV and the unrelated murine retroviruses Moloney murine leukemia virus (MMuLV) and mouse mammary

130 etherin markedly inhibits the replication of Moloney murine leukemia virus (Mo-MLV) and is required f

131 Both the RNase H domain of Moloney murine leukemia virus (Mo-MLV) reverse transcrip

132 A crystallographic study of the Moloney murine leukemia virus (Mo-MLV) RNase H domain wa

133 The capsid (CA) domain of the Moloney murine leukemia virus (Mo-MuLV) Gag protein has

134 be transgenic mice expressing fusions of the Moloney murine leukemia virus (Mo-MuLV) Gag protein to s

135 d the polypurine tract (PPT) sequence in the Moloney murine leukemia virus (Mo-MuLV) genome.

136 Previous studies with Moloney murine leukemia virus (Mo-MuLV) identified two a

137 nuclear localization signals (NLSs) into the Moloney murine leukemia virus (Mo-MuLV) integrase (IN) p

138 B1/DNMT3A/DNMT3L complex to newly integrated Moloney murine leukemia virus (Mo-MuLV) proviral DNA.

139 Recombinant Moloney murine leukemia virus (Mo-MuLV)-based retrovirus

140 This agent is a Moloney murine leukemia virus (Mo-MuLV)-based virus that

141 The core site in the Moloney murine leukemia virus (Moloney MLV) enhancer was

142 tion of a novel domain in the Gag protein of Moloney murine leukemia virus (MoLV) that is important f

143 an immunodeficiency virus type 1 (HIV-1) and Moloney murine leukemia virus (MoMLV) cDNA.

144 es, whereas the prototypical gammaretrovirus Moloney murine leukemia virus (MoMLV) favors strong enha

145 Moloney murine leukemia virus (MoMLV) Gag utilizes its l

146 1), feline immunodeficiency virus (FIV), and Moloney murine leukemia virus (MoMLV) integrases were st

147 Retroviral reverse transcriptase (RT) of Moloney murine leukemia virus (MoMLV) is expressed in th

148 n factor (BAF) blocks the autointegration of Moloney murine leukemia virus (MoMLV) PICs in vitro.

149 To examine the role of this domain in Moloney murine leukemia virus (MoMLV) replication, we an

150 The Moloney murine leukemia virus (MoMLV) ribonucleoprotein

151 polymerase, but not the RNase H function of Moloney Murine Leukemia Virus (MoMLV) RT and also inhibi

152 ays which show that tetherin does not affect Moloney murine leukemia virus (MoMLV) spread, and only m

153 he HIV-1 vector was also more efficient than Moloney murine leukemia virus (MoMLV) vectors for transd

154 nd particle ultrastructure highly similar to Moloney murine leukemia virus (MoMLV), another gammaretr

155 xamine the early events in the life cycle of Moloney murine leukemia virus (MoMLV), we analyzed the i

156 lope protein (Env) can be used to pseudotype Moloney murine leukemia virus (MoMLV)-based retrovirus v

157 This is in contrast to a Moloney murine leukemia virus (MoMLV)-based retrovirus v

158 Previous studies have suggested that Moloney murine leukemia virus (MoMLV)-based vectors pseu

159 Moloney murine leukemia virus (MoMLV)-derived vectors re

160 erization linkage structure in the genome of Moloney murine leukemia virus (MoMLV).

161 Retroviral vectors based on the Moloney murine leukemia virus (MoMuLV) are currently the

162 The ts1 mutant of the Moloney murine leukemia virus (MoMuLV) causes neurodegen

163 To investigate receptor-mediated Moloney murine leukemia virus (MoMuLV) entry, the green

164 Recent studies with small fragments of the Moloney murine leukemia virus (MoMuLV) genome suggested

165 The ts1 mutant of Moloney murine leukemia virus (MoMuLV) induces a neurode

166 The envelope (Env) protein of Moloney murine leukemia virus (MoMuLV) is a homotrimeric

167 ropathogenic temperature-sensitive mutant of Moloney murine leukemia virus (MoMuLV-ts1), results in m

168 Moloney murine leukemia virus (MuLV) preferentially capt

169 rmation from scarce, femtomole quantities of Moloney murine leukemia virus (MuLV) RNA inside authenti

170 free Mg(2+) (~0.25 mM) and is comparable to Moloney murine leukemia virus (MuLV) RT fidelity.

171 In the gammaretroviruses, typified by Moloney murine leukemia virus (MuLV), gag and pol are in

172 The provirus integration site for Moloney murine leukemia virus (Pim) 1 kinase is an oncog

173 ess oncogenic (proviral integration site for Moloney murine leukemia virus (PIM) 1, 2, and 3 kinases

174 Proviral integration site for Moloney murine leukemia virus (Pim) kinases are serine/t

175 onine-specific proviral integration site for Moloney murine leukemia virus (PIM) kinases PIM1 and PIM

176 We also determined whether the wild type Moloney murine leukemia virus (wt-MoMuLV) and one of its

177 nregulation of proviral integration site for Moloney murine leukemia virus 1 kinase (PIM-1).

178 e kinase PIM1 (Proviral Integration site for Moloney murine leukemia virus 1) has emerged as a key re

179 oplasmic domain derived from the amphotropic Moloney murine leukemia virus 4070A GP, revealed about 1

180 n cells expressing envelope protein (Env) of Moloney murine leukemia virus and target cells were stud

181 able to gene delivery by wild-type ecotropic Moloney murine leukemia virus and vesicular stomatitis v

182 l helper virus, pAM3-IRES-Zeo, that contains Moloney murine leukemia virus as a helper virus and a pi

183 ssive cis-acting DNA sequences identified in Moloney murine leukemia virus but remains sensitive to t

184 e full length, positive-strand genome of the Moloney Murine Leukemia Virus contains a "core encapsida

185 sults also suggest that the leader region of Moloney murine leukemia virus contains inhibitory/regula

186 istones are rapidly loaded onto unintegrated Moloney murine leukemia virus DNAs.

187 erived MLE-15 cells infected with a chimeric Moloney murine leukemia virus driven by the JSRV enhance

188 MEL cells were infected with a Moloney murine leukemia virus encoding the green fluores

189 The trimeric Moloney murine leukemia virus Env protein matures by two

190 l receptor-binding sequence of the ecotropic Moloney murine leukemia virus envelope glycoprotein with

191 we have studied how the protomeric units of Moloney murine leukemia virus envelope protein (Env) are

192 e we report that tryptophan 142 in ecotropic Moloney murine leukemia virus envelope protein is essent

193 Additionally, the MMTV- and Moloney murine leukemia virus envelope proteins coimmuno

194 We have examined the function of Moloney murine leukemia virus envelope proteins with sub

195 Two second-site mutations in Moloney murine leukemia virus envelope surface protein (

196 by eight footprints representing regions of Moloney murine leukemia virus gag, some previously uncha

197 dful" was tested by examining the ability of Moloney murine leukemia virus genomes lengthened by 4, 8

198 coated with the parental wild-type ecotropic Moloney murine leukemia virus glycoprotein through the e

199 al analyses of the p12 Gag phosphoprotein of Moloney murine leukemia virus have demonstrated its part

200 nuclear magnetic resonance structure of the Moloney murine leukemia virus IN (M-MLV) C-terminal doma

201 n methylating the 3' long terminal repeat of Moloney murine leukemia virus in vitro.

202 To study the function of the HHCC domain of Moloney murine leukemia virus IN, the first N-terminal 1

203 receptor-5-positive (Lgr5(+)) and B lymphoma moloney murine leukemia virus insertion region homolog-1

204 The B-lymphoma Moloney murine leukemia virus insertion region-1 protein

205 rabidopsis (Arabidopsis thaliana) B lymphoma Moloney murine leukemia virus insertion region1 homolog

206 B-cell-specific Moloney murine leukemia virus integration site 1 (BMI1)

207 e examine the role of Bmi-1 (B-cell-specific Moloney murine leukemia virus integration site 1) as a r

208 The p12 Gag protein of Moloney murine leukemia virus is a small polypeptide of

209 The envelope (Env) protein of Moloney murine leukemia virus is the primary mediator of

210 igh expression of proviral insertion site of Moloney murine leukemia virus kinases (Pim-1, -2, and -3

211 ng hybrid duplex substrates derived from the Moloney murine leukemia virus long terminal repeat, we i

212 internal grp78 promoter, in contrast to the Moloney murine leukemia virus long terminal repeat, wher

213 xpression in vivo from vectors driven by the Moloney murine leukemia virus long-terminal repeat (LTR)

214 repeat (LTR) was found to be higher than the Moloney murine leukemia virus LTRs in both LNCaP and WPM

215 Moreover, Moloney murine leukemia virus NC, which contains a singl

216 We find that Moloney murine leukemia virus nucleocapsid protein reduc

217 irus type 1 nucleocapsid protein and for the moloney murine leukemia virus nucleocapsid zinc knuckle

218 tated sequences both within and flanking the Moloney murine leukemia virus polypurine tract (PPT) and

219 le of forming heterodimeric species with the Moloney murine leukemia virus Psi domain.

220 Homology requirements for Moloney murine leukemia virus recombination were address

221 Neonatal infection of these mice with Moloney murine leukemia virus resulted in accelerated tu

222 n which the host, the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase (MML

223 Inhibitor resistance of several commercial Moloney murine leukemia virus reverse transcriptase (MML

224 an effort to increase the thermostability of Moloney Murine Leukemia Virus reverse transcriptase (MML

225 A resolution of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase comp

226 A 157-amino-acid fragment of Moloney murine leukemia virus reverse transcriptase enco

227 Template switching rates of Moloney murine leukemia virus reverse transcriptase muta

228 ed on the ability of the RNase H activity of Moloney murine leukemia virus reverse transcriptase to c

229 , including D114A and R116A substitutions in Moloney murine leukemia virus reverse transcriptase, are

230 conserved residues in the fingers domain of Moloney murine leukemia virus reverse transcriptase, res

231 t includes the fingers and palm domains from Moloney murine leukemia virus reverse transcriptase.

232 n of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptases wit

233 ng model hybrid substrates and the HIV-1 and Moloney murine leukemia virus reverse transcriptases, we

234 These compounds also inhibit Moloney murine leukemia virus RT but not the Klenow frag

235 Avian myeloblastosis and Moloney murine leukemia virus RTs also bound more stably

236 ddition, PARP-1-deficient MEFs infected with Moloney murine leukemia virus showed no decrease in viru

237 he generation of retroviral vectors based on Moloney murine leukemia virus that specifically transduc

238 ic HTLV-1 with a replaced envelope gene from Moloney murine leukemia virus to allow HTLV-1 to fuse wi

239 substitutions were introduced into the NC of Moloney murine leukemia virus to examine further its rol

240 We used Moloney murine leukemia virus to induce lymphomas in p27

241 s on the neurovirulent viruses FrCas(NC) and Moloney murine leukemia virus ts1 indicate that the nasc

242 and (hTRAIL), into a cell line that packages Moloney murine leukemia virus vectors.

243 Replicating Moloney murine leukemia virus viral production was great

244 e Hsp70 was not detected in association with Moloney murine leukemia virus virions.

245 onlentiviral MAs and does not associate with Moloney murine leukemia virus virions.

246 TM cleavage in Moloney murine leukemia virus was inhibited by amprenavi

247 1 (fti-1) (feline leukemia virus) and Ahi-1 (Moloney murine leukemia virus) shows that these display

248 rotein (GFP)-transducing retroviral vectors, Moloney murine leukemia virus, and lentivirus.

249 ces between XMRV and the intensively studied Moloney murine leukemia virus, architectures of the regu

250 mate lentiviruses and distinct from those of Moloney murine leukemia virus, avian sarcoma leukosis vi

251 retrovirus, MoFe2, or with the parent virus, Moloney murine leukemia virus, caused significant reduct

252 The retrovirus ts1, a mutant of Moloney murine leukemia virus, causes oxidative stress a

253 ation, followed by reverse transcription via Moloney murine leukemia virus, degradation of chromosoma

254 For Moloney murine leukemia virus, primer removal at the RNA

255 elops in mice infected with ts1, a mutant of Moloney murine leukemia virus, resembles human AIDS.

256 eviously, we have shown that, in the case of Moloney murine leukemia virus, the U3 region of the LTR

257 In Moloney murine leukemia virus, three stem-loops are impo

258 pendent kinase proviral integration site for Moloney murine leukemia virus-1 (PIM-1), which in turn r

259 evere combined immunodeficiency (SCID-X1), a Moloney murine leukemia virus-based gamma-retrovirus vec

260 atal mice were injected intravenously with a Moloney murine leukemia virus-based retroviral vector (R

261 Moloney murine leukemia virus-based retroviral vector ex

262 in transduction efficiency by both HIV- and Moloney murine leukemia virus-based retroviral vectors.

263 A Moloney murine leukemia virus-based single-replication-c

264 cur between two identical sequences within a Moloney murine leukemia virus-based vector.

265 HIV-1 replication than cells transduced with Moloney murine leukemia virus-based vectors expressing T

266 te dehydrogenase (hG6PD) gene transferred by Moloney murine leukemia virus-based vectors into murine

267 To address this hypothesis, Moloney murine leukemia virus-based vectors, which were

268 deletion of sequences in the 3' U3 region of Moloney murine leukemia virus-derived retroviral vectors

269 Moloney murine leukemia virus-like particles (M-VLPs) we

270 tants of Hrs had no effect on the release of Moloney murine leukemia virus.

271 eracting with the capsid (CA) protein of the Moloney murine leukemia virus.

272 ), function as transcriptional activators of Moloney murine leukemia virus.

273 ysis of 639 nucleotides in the gag region of Moloney murine leukemia virus.

274 man immunodeficiency virus type 1 (HIV-1) or Moloney murine leukemia virus.

275 long terminal repeat (LTR) sequences of the Moloney murine leukemia virus.

276 ed by ts1, a temperature-sensitive mutant of Moloney murine leukemia virus.

277 of the dimerization and packaging domain of Moloney murine leukemia virus.

278 d to be loaded onto unintegrated DNAs of the Moloney murine leukemia virus.

279 study, we tested replication properties for Moloney murine leukemia viruses with targeted mutations

280 elet-derived growth factor (PDGF)-containing Moloney murine leukemia viruses.

281 oduce an in vitro methylated or unmethylated Moloney murine leukemia-based provirus in MEL cells.

282 Mice were challenged with the Moloney murine sarcoma and leukemia virus complex (M-MSV

283 The fundamental dimerization unit for the Moloney murine sarcoma gamma retrovirus spans a 170-nucl

284 examination of the in vitro dimerization of Moloney murine sarcoma virus (MuSV) RNA in the context o

285 iously, we proposed that dimerization of the Moloney murine sarcoma virus genomic RNAs relies upon th

286 dimerization active sequence (MiDAS) for the Moloney murine sarcoma virus in the final dimer state us

287 We investigated the features of the Moloney murine sarcoma virus leader sequence necessary f

288 , a 2954-base-pair (bp) laboratory-generated Moloney murine sarcoma virus, induced subcutaneous tumor

289 Mutant mice injected with Moloney murine sarcoma/leukemia virus develop significan

290 cogenic kinase proviral integration site for Moloney-murine leukemia 1 (PIM1) in CD127+ T-ALL/T-LBL,

291 ory activity toward proviral integrations of Moloney (PIM) virus 3 kinase but not ZIPK, had no effect

292 , expressed by tumor cells induced by Friend/Moloney/Rauscher (FMR) MuLV, is not immunogenic, even wh

293 Current strategies for genetic therapy using Moloney retroviruses require ex vivo manipulation of hem

294 on was associated with compromised Ccnb1 and Moloney sarcoma oncogene (Mos) mRNA translation, delayed

295 ts as a chimeric transcription factor on the Moloney sarcoma virus long terminal repeat and a synthet

296 e beta1-subunit (Na,K-beta) in highly motile Moloney sarcoma virus-transformed Madin-Darby canine kid

297 Moloney sarcoma virus-transformed Madin-Darby canine kid

298 Moloney sarcoma virus-transformed MDCK cells (MSV-MDCK)

299 ced both nondividing and dividing cells; the Moloney vector only transduced the latter.

300 nificant shift in disease specificity of the Moloney virus from T-cell leukemia to erythroleukemia.