ライフサイエンスコーパス: molting

1 elopmental parameters (survival, weight, and molting).

2 ir outermost structures during growth and/or molting.

3 on hormone (EH), a neuropeptide regulator of molting.

4 ng the lethargus period that precedes larval molting.

5 g pads without affecting isometric growth or molting.

6 clear hormone receptors essential for larval molting.

7 terial found between the two cuticles during molting.

8 erized by defects in pharyngeal function and molting.

9 mately 97% of larval survival and successful molting.

10 proteins that have an essential role during molting.

11 rrounding syncytia and pronounced defects in molting.

12 near the end of juvenile instars, and during molting.

13 nd functional maturation of their ORNs after molting.

14 tions of molting animals, oxygen binding and molting.

15 from moths that is expressed coincident with molting.

16 hypoxia leads to growth and ecdysone-induced molting.

17 to affecting tick blood meal engorgement and molting.

18 1F1) is an important regulator of C. elegans molting.

19 e specification, animal size regulation, and molting.

20 o the surrounding matrices and fluids during molting.

21 ynthesis, imaginal cell size, and control of molting.

22 enesis, early larval development, and larval molting.

23 egradative and biosynthetic process known as molting.

24 tal pollutant concentrations were similar in molting (3.3-5.7 ng g(-1) ww) and breeding penguins (ran

25 timing and location of pre-migratory feather molting, a period when feathers are shed and replaced wi

26 400 Ma, a number of insect groups continued molting after forming functional wings.

27 Today, however, flying insects stop molting after metamorphosis when they become fully winge

28 Molting after the normal first instar period was restore

29 cantly elevated mortality rates and impaired molting already in the lowest tested concentrations of e

30 rdinated movement, adult sterility, abnormal molting and aberrant collagen deposition.

31 Normally, ecdysone positively regulates both molting and antimicrobial peptide production, so the ina

32 abnormal epidermal cell function, including molting and body size regulation, suggesting that CHR3 i

33 Long-term fasting (25 days) for molting and breeding led, respectively, to a 1.8- and 2.

34 al ecdysteroid agonists for EcR that disrupt molting and can be used as safe pesticides.

35 15 weeks, with infective third-stage larvae molting and developing into the late fourth-stage larvae

36 he importance of FTZ-F1 nuclear receptors in molting and developmental control across evolutionarily

37 Molting and ecdysis in vitro required entry of the paras

38 In premolt, a preparation stage for upcoming molting and energy consumption, highly expressed genes w

39 n mutant background partially rescues larval molting and growth.

40 nctional maturation is not synchronized with molting and may not be completed until many weeks after

41 acle (USP) heterodimer is a key regulator in molting and metamorphoric processes, activating and repr

42 inates growth and maturation, represented by molting and metamorphosis [2].

43 the steroid hormone ecdysone trigger larval molting and metamorphosis and coordinate aspects of embr

44 We studied the regulation of molting and metamorphosis in bed bugs with a goal to ide

45 Ecdysteroids initiate molting and metamorphosis in insects via a heterodimeric

46 e orthologs of NR genes that function during molting and metamorphosis in insects.

47 orms of the ecdysone receptor (EcR) initiate molting and metamorphosis of insects.

48 expression of genes known to be involved in molting and metamorphosis showed high levels of Kruppel

49 ing developmental transitions such as larval molting and metamorphosis through its active metabolite

50 (HaCHI) gene, critically required for insect molting and metamorphosis was selected as a potential ta

51 ne receptor gene generated defects in larval molting and metamorphosis, resulting in animals that fai

52 ing developmental transitions such as larval molting and metamorphosis.

53 ecdysone, a steroid hormone that stimulates molting and metamorphosis.

54 developmental events in arthropods including molting and metamorphosis.

55 ese polyhydroxylated sterols is critical for molting and metamorphosis.

56 ecdysone-regulated events during Drosophila molting and metamorphosis.

57 B/ATF proteins in essential functions during molting and metamorphosis.

58 n of insects from microbial infection during molting and metamorphosis.

59 bryonic developmental transitions, including molting and metamorphosis.

60 land coordinates and triggers events such as molting and metamorphosis.

61 ate developmental transitions such as larval molting and metamorphosis.

62 s several developmental processes, including molting and morphogenesis, and results in larval lethali

63 to identify a suite of genes associated with molting and pair this with gene-environment association

64 tants display defects associated with larval molting and pupariation.

65 pmental transitions in Drosophila, including molting and puparium formation.

66 T-7), that is responsible for proper cuticle molting and re-synthesis.

67 These studies suggest that molting and successful development of L4 depends on the

68 vity was capable of affecting O. volvulus L3 molting and that the presence of both activities in a si

69 This positive system that promotes molting and the negative control via the critical weight

70 ontrols growth, and at high levels it causes molting and tissue differentiation.

71 roteins, and a significant reduction in both molting and viability of third-stage larvae.

72 of feather follicles undergo physiological (molting) and plucking injury-induced regeneration in chi

73 that supports approximately 97% survival and molting, and a 150% increase in larval weight after 10 d

74 variables and the sequence of blood feeding, molting, and aging.

75 occur in fossils, as well as in developing, molting, and flight-impaired birds.

76 ia magna (D. magna), impairing reproduction, molting, and maturation time; however, recovery from FPW

77 bon is required for male viability, molting, and numerous events in metamorphosis including

78 ar receptor cofactor required for viability, molting, and numerous morphological events.

79 of their dependence on sea ice for feeding, molting, and parturition.

80 g acquired by ticks, persisting through tick molting, and reinfecting new mammalian hosts.

81 these ticks did not retain spirochetes upon molting, and subsequent B. burgdorferi transmission by a

82 on of three life history parameters (weight, molting, and survival).

83 cyte differentiation, embryonic development, molting, and synaptic plasticity.

84 the epidermal epithelium for animal growth, molting, and the proper pattern of seam-cell divisions.

85 cally expressed nuclear hormone receptors in molting, and to analyze meiosis-specific roles for prote

86 otostomes, including the segmented annelids, molting animals (Ecdysozoa) are commonly considered inca

87 hophora + Tardigrada + Arthropoda) and other molting animals (Ecdysozoa), we analyzed the transcripto

88 oins nematodes with arthropods in a clade of molting animals, Ecdysozoa.

89 ns-may participate in two vital functions of molting animals, oxygen binding and molting.

90 be monophyletic and placed within a clade of molting animals, the ecdysozoans, with nematodes and six

91 stigate evolutionary relationships among all molting animals.

92 used associated locations to define two key molting areas.

93 EcR-B mutant animals show defects in larval molting, arresting at the boundaries between the three l

94 let-7 express genes characteristic of larval molting as they initiate a supernumerary molt.

95 We show that low oxygen tension induces molting at smaller body size, consistent with the hypoth

96 RNA genes mir-48 and mir-84 exhibit retarded molting behavior and retarded adult gene expression in t

97 s hemocyte markers, impacting blood-feeding, molting behavior, and bacterial acquisition.

98 calize with peptide hormones known to elicit molting behavior, suggesting the involvement of novel re

99 survival rate was observed, together with a molting block, These findings confirm the important regu

100 The thatch is not discarded at molting but is enlarged by addition of strands as the la

101 v-SPI proteins play a vital role in nematode molting by controlling the activity of an endogenous ser

102 Prevention of pupa to adult molting by JHA was differentially higher at elevated tem

103 in the target cells and often--because of a molting checkpoint--arrests development globally.

104 filling of the diverticula is linked to the molting cycle and possibly involved therein.

105 mplete the larval molts but fail to exit the molting cycle at the adult stage.

106 mir-84 and let-7 promote exit from the molting cycle by regulating targets in the heterochronic

107 The molting cycle is decelerated in nhr-23 knockdowns and ac

108 of JHSB3 were studied during the 10-day long molting cycle of 4(th) instar nymph, between a blood mea

109 es of the JH biosynthetic pathway during the molting cycle of 4(th) instar.

110 We propose that the molting cycle of C. elegans involves the dynamic assembl

111 During each molting cycle of insect development, synthesis of new cu

112 The molting cycle of nematodes involves the periodic synthes

113 To complete each molting cycle, insects display a stereotyped sequence of

114 fic changes in Cas-PMCA abundance during the molting cycle, with peak expression occurring during pre

115 inal neurohormone released at the end of the molting cycle.

116 elopment in neuronal cells that regulate the molting cycle.

117 A major driver of this variation is the molting cycle.

118 abolism and physiological responses during a molting cycle.

119 . elegans development, in synchrony with the molting cycle.

120 e distinct but interconnected aspects of the molting cycle.

121 that LIN-42A and affiliated factors regulate molting cycles in much the same way that PER-based oscil

122 C. elegans molting cycles involve rhythmic cellular and animal beha

123 occurs relative to the approximately 6-hour molting cycles of postembryonic development.

124 fluctuate in a reiterated pattern during the molting cycles, reminiscent of the expression hierarchy

125 hythmic development, reflected in C. elegans molting cycles.

126 e molting program including the cessation of molting cycles.

127 The molting defect induced by Ce-imp-2 deficiency was mimick

128 t abnormalities, appeared independent of the molting defect.

129 s eliminated in larvae carrying mutations in molting defective (mld), a gene encoding a nuclear zinc

130 Comparison to molting-defective lrp-1(ku156) mutants revealed that the

131 ans, which emerged from a genetic screen for molting-defective mutants sensitized by low cholesterol.

132 l arrest, abnormal reproductive development, molting defects and increased adult longevity.

133 n apl-1(yn5) background caused lethality and molting defects at all larval stages, suggesting that ap

134 n chitinase-dependent loss of chitin, severe molting defects, and lethality at all developmental stag

135 y others in screens for genes causing larval molting defects, is identified here as a novel P-granule

136 ll differentiation contributes to peb-1(cu9) molting defects.

137 ed mutant phenotypes such as burst vulva and molting defects.

138 lopmental delays, developmental arrests, and molting defects.

139 rig mutants display defects in molting, delayed larval development, larval lethality, d

140 tive action of chitinases and possibly other molting enzymes.

141 enodytes patagonicus during the breeding and molting fasts, which are marked by low and high levels o

142 The molting fluid enzyme chitinase, which degrades the matri

143 t to serve as a physical barrier, preventing molting fluid enzymes from accessing the new cuticle and

144 ection of the newly synthesized cuticle from molting fluid enzymes has long been attributed to the pr

145 have the subimago stage despite the risk of molting fragile membranous wings.

146 A decrease in the percentage of larvae molting from the third stage to the fourth stage was obs

147 In D. immitis, molting from the third to the fourth larval stage can be

148 mulates ecdysteroid production by crustacean molting glands (Y-organs).

149 uth of their core sub-Antarctic breeding and molting grounds.

150 stent areas of high SIC provide an important molting habitat for Adelie penguins.

151 they use sea ice as a breeding, foraging and molting habitat.

152 We show that interinstar molting has the same size-related oxygen-dependent mecha

153 ates sterol homeostasis and is essential for molting hormone (20-hydroxyecdysone; 20E) biosynthesis.

154 s of the ring gland that produce ecdysteroid molting hormone (EC).

155 cline in the circulating titer of the insect molting hormone 20-hydroxyecdysone (20-HE).

156 The steroid insect molting hormone 20-hydroxyecdysone is believed to contro

157 s degrees by feeding the mutants the steroid molting hormone 20-hydroxyecdysone, or the precursors of

158 teps in the conversion of cholesterol to the molting hormone 20-hydroxyecdysone.

159 ophila polytene chromosomes initiated by the molting hormone 20-hydroxyecdysone.

160 ecdysteroids, herbal analogues of the insect molting hormone and their semisynthetic derivatives, wer

161 lex that mediates the effects of the steroid molting hormone ecdysone by activating and repressing ex

162 with a molt, triggered by release of steroid molting hormone ecdysone from the prothoracic gland (PG)

163 , growth ceases in response to a peak of the molting hormone ecdysone that coincides with a nutrition

164 The molting hormone ecdysone triggers chromatin changes via

165 TTH), which stimulates the production of the molting hormone ecdysone via an incompletely defined sig

166 Because the PGs produce the molting hormone ecdysone, we hypothesized that ecdysone

167 of ecdysteroids that includes the principal molting hormone, 20-hydroxyecdysone (20E), and ecdysone

168 stage can be induced in vitro by the insect molting hormone, 20-hydroxyecdysone, suggesting that thi

169 s known to increase levels of the growth and molting hormone, ecdysone, which also regulates the expr

170 only known function is the production of the molting hormone, ecdysone.

171 functions as a receptor for the ecdysteroid molting hormones of insects.

172 racteristic concentration of the ecdysteroid molting hormones that regulate metamorphosis.

173 Synthesis of ecdysteroids (molting hormones) by crustacean Y-organs is regulated by

174 The prepupal peak of ecdysteroids (molting hormones) triggers the regression of APR dendrit

175 ation of the hypodermis and the cessation of molting in C. elegans.

176 olism and biological processes pertaining to molting in crustaceans.

177 ties have also been found to be critical for molting in O. volvulus L3 larvae.

178 ion level of chitinase 1 and caused abortive molting in the insects.

179 h the new and the old cuticles during larval molting, in particular in the regions that are degraded

180 PIXR abrogation also impairs larval molting, indicative of its role in tick biology.

181 breeders (net mobilization) but decreased in molting individuals (net excretion), suggesting a signif

182 ae were fed on EMLA-infected mice, and after molting, infected nymphs were used to infest naive anima

183 Molting is a critical developmental process for crustace

184 Molting is a key feature of Ecdysozoa, but little is kno

185 Nematode molting is a remarkable process where animals must repea

186 Molting is elicited by a critical titer of ecdysteroids

187 ther, our integrative analysis suggests that molting is in part regulated by genes linked to feather

188 Crustacean molting is known to be regulated largely by ecdysteroids

189 A new study demonstrates that molting is regulated by the ecdysteroid hormone in the t

190 Molting is required for progression between larval stage

191 Onchocerca volvulus third-stage larvae (L3), molting L3 (mL3), and crude extract from adult males (M-

192 nfective larval (third-stage larvae [L3] and molting L3 [mL3]), adult female worm (F-OvAg), and skin

193 Secondly, by immunoscreening the molting L3 cDNA library with a pool of human sera from p

194 fection, the third-stage larvae (L3) and the molting L3.

195 endogenous cysteine protease was detected in molting larvae after binding to labeled inhibitors, and

196 o Ov-spi transcripts are up-regulated in the molting larvae and adult stages of the development of th

197 he separation between the cuticles occurs in molting larvae.

198 y avoidance of octanol and quiescence during molting lethargus.

199 as arousal thresholds and quiescence during molting lethargus.

200 DA1877 affects cyclic gene expression during molting, likely through the nuclear hormone receptor NHR

201 inates the expression of factors involved in molting, lipid transport/metabolism and remodeling of th

202 jor aspects of insect development, including molting, metamorphosis, and reproduction.

203 n suggests that the function of CPZ-1 during molting might be conserved in other nematodes.

204 survival of third stage larvae (L3), and the molting of L3 to L4 in vitro.

205 are insecticides that prevent pupa to adult molting of mosquitoes by mimicking the action of their n

206 osantel was found also to completely inhibit molting of O. volvulus infective L3 stage larvae.

207 Chitinases that function in the molting of the larval exoskeleton have been characterize

208 Frequent molting of the shrimp may be explained by an intensified

209 vae also show defects in tracheal growth and molting of their tracheal cuticle.

210 T5, was found to be required for pupal-adult molting only.

211 crust expression with gender, social status, molting or feeding, dominant animals show significantly

212 singly, PTTH production is not essential for molting or metamorphosis.

213 In both sexes, lep-2 mutants fail to cease molting or produce an adult cuticle.

214 The monophyly of Ecdysozoa, molting organisms, was not supported by any of the analy

215 mutant suggests that cpz-1 has a role in the molting pathways.

216 Alaska (1998-2010), sampled during breeding/molting periods.

217 o determine population genetic structure and molting phenotype across thirteen breeding sites.

218 p-2 leads to embryonic death and an abnormal molting phenotype in Caenorhabditis elegans.

219 e genetic and ecological drivers of distinct molting phenotypes.

220 may result in natural selection for distinct molting phenotypes.

221 We have identified a regulator of molting, pqn-47.

222 tor, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitte

223 ecdysone and/or ponasterone A initiates the molting process through binding to its conserved heterod

224 chitinase family genes, primarily during the molting process, and provide a biological rationale for

225 gest that pqn-47 executes key aspects of the molting program including the cessation of molting cycle

226 pation but was dispensable for larval-larval molting, pupation, and adult eclosion.

227 ytic domains, prevented embryo hatch, larval molting, pupation, and adult metamorphosis, indicating a

228 ecifically, estradiol concentrations in late molting seals decreased by 50% across the range of muscl

229 high as 9.5 pM during the M. angustirostris molting season.

230 anugo pups, Hg concentrates in the hair, and molting serves as a main detoxification route.

231 or: camouflage mismatch in seasonally colour molting species confronting decreasing snow cover durati

232 will be critical for hares and other colour molting species to keep up with climate change.

233 ified differentially expressed genes at four molting stages of Chinese mitten crab (Eriocheir sinensi

234 erentially expressed genes amongst different molting stages, provide novel insights into the function

235 s differentially expressed amongst different molting stages.

236 mice, and (iii) able to persist through tick molting stages.

237 ly control the production and release of the molting steroid ecdysone.

238 Our results demonstrate that the molting steroid hormone ecdysone in adult Drosophila is

239 Histological evidence of molting suggests that after summer had passed, molt bega

240 f animals to sync the timing and location of molting (the replacement of hair, skin, exoskeletons or

241 Upon molting, their eye tubes elongate in less than an hour,

242 -1, was identified through the analysis of a molting third-stage larvae expressed sequence tag datase

243 e basal layer of the cuticle of third-stage, molting third-stage, and fourth-stage larvae, the body c

244 us, while loss of PAN-1 in the soma inhibits molting, this report demonstrates that PAN-1 is also a P

245 The ecdysteroids induce and direct molting through the ecdysone receptor (EcR), a nuclear h

246 e propose that this feedback loop unites the molting timer and the heterochronic gene regulatory netw

247 Examples in entomology include molting times and death times of insects, waiting times

248 for crq display impaired feeding and delayed molting to adulthood due to a deficiency in ecdysteroid

249 efficiently transmitted the ehrlichiae after molting to nymphs, thereby demonstrating vector competen

250 lus microplus ticks could acquire and, after molting to the adult stage, transmit B. equi to naive ho

251 PCR positive, after feeding on the sheep and molting to the next instar, increased marginally with in

252 This mechanism enables exoskeletal molting, tube expansion, and epithelial integrity.

253 Molting was completely inhibited in the presence of 50-2

254 its biological activities on O. volvulus L3 molting was investigated.

255 ctor, NHR-23/NR1F1, in regulating C. elegans molting, we discovered that NHR-23/NR1F1 is also constit

256 Consistent with a function in molting, we found that PEB-1 was detectable in all hypod

257 gland cells have prominent functions during molting, we suggest defective gland cell differentiation

258 ruitment, inhibits reproduction, and induces molting, with no change in plasma prolactin levels.

259 uctor-A causes severe defects during cuticle molting, wound protection, tube expansion and larval gro