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1 enzyme somewhat more slowly than that of the monocyclic.
2                                          The monocyclic 1,2,3-thiadiazoles do not inactivate any of t
3 5-fused bicyclic and three 4,5-disubstituted monocyclic 1,2,3-thiadiazoles have been examined for the
4                          N2 elimination from monocyclic 1,2,3-triazoles can generate iminocarbenes, 1
5 irst general late-stage functionalization of monocyclic 1,2-azaborines at the C(6) position is descri
6 remains a long-standing challenge to prepare monocyclic 1,2-azaborines, particularly multi-substitute
7 azaborine (2) to furnish new 2,3-substituted monocyclic 1,2-azaborines.
8 is a tribute to Dewar's first synthesis of a monocyclic 1,2-dihydro-1,2-azaborine 50 years ago and di
9 ular aldol reaction of two differently sized monocyclic 1,3-diketones bearing a chiral, oxygenated si
10  method for the synthesis of a wide range of monocyclic 1,4-azaborines, including the first examples
11 o-2,6-dioxaphosphorinanone(3)-1-oxide] and a monocyclic [1-hydroxy-4-phenyl-2,6-dioxaphosphorinanone(
12                                              Monocyclic [11]annulenium cations, which are experimenta
13                                These include monocyclics 3, bicyclics 4, tricyclics 5, and tetracycli
14                                          The monocyclic 5-thiapyrimidinones were synthesized by coupl
15                                Specifically, monocyclic, 6, 5-bicyclic, and 6,7-bicyclic structures p
16 ters, and four tertiary stereocenters from a monocyclic, achiral precursor.
17 ) appear to differ significantly from the OH-monocyclic adduct + O(2) reactions.
18  shifted to Ser14-Asp17 in the weakly potent monocyclic agonist II.
19 opening metathesis polymerization of several monocyclic alkenes as well as norbornene and oxanorborne
20 ulted in their reductive cyclization to form monocyclic alkenes in moderate yields, in addition to th
21 ting and pi-accepting properties compared to monocyclic (alkyl)(amino)carbenes (CAACs).
22 y a second C-methyltransferase furnishes the monocyclic alpha-prechlororaphen pyrophosphate (alpha-PC
23           However, 6-methylsalicylic acid, a monocyclic analog of the reactive ring, is not recognize
24                         In comparison to the monocyclic analog, epsilon-caprolactone (CL), ODO has a
25         The helical content in water of both monocyclic analogs I and II is approximately 22%; that o
26 r of galactopyranose derivatives relative to monocyclic analogs.
27 stem was found to be more selective than its monocyclic analogue beta-proline 5b.
28 Attempts to perform this ring expansion on a monocyclic analogue have been also explored to evaluate
29                              The most potent monocyclic analogues were cyclo(4-10)[Ac-DNal(1), DFpa(2
30                                          The monocyclic analogues with a C-4 chloro group did show so
31 itude for the bicyclic phospholanes over the monocyclic analogues.
32                                         Both monocyclic and benzofused ketone derived beta-keto sulfo
33 and coupled cluster calculations on numerous monocyclic and bicyclic (CH)12(*-) isomers.
34                                              Monocyclic and bicyclic agonists based on sunflower tryp
35                      A series of substituted monocyclic and bicyclic azepinones were incorporated as
36                                              Monocyclic and bicyclic cyclobutylanilines successfully
37 zation under physiologic conditions to yield monocyclic and bicyclic peptides.
38 tes are slow and reversible, and mixtures of monocyclic and bicyclic products are formed.
39  method can be used to construct an array of monocyclic and bicyclic scaffolds, many of which are fou
40 ineering that unlocked the path to alternate monocyclic and bicyclic synthons representing the basis
41                                 A variety of monocyclic and bicyclic vinylidene cyclopropanes can be
42 ation for conversion of structurally diverse monocyclic and fused aromatics to the corresponding prim
43 ed for selective and efficient ionization of monocyclic and polycyclic aromatic hydrocarbons.
44 thod provides a straightforward synthesis of monocyclic and spiro beta- or gamma-lactams with good to
45 cubane, prismane, tetrahedrane, and expanded monocyclics and bicyclics were optimized at the HF/6-31G
46  piperazinyl group with a variety of linear, monocyclic, and bicyclic diamines.
47 is group of catalysts that generate acyclic, monocyclic, and bicyclic olefin products.
48 induces ring opening to afford predominantly monocyclic anti-1,2-hydroxamic acids 12.
49 induces ring opening to afford predominantly monocyclic anti-1,4-hydroxamic acids 3.
50 -PAH)Mn(CO)(3)(+) complexes in comparison to monocyclic arene analogues.
51 y shorter than the alternative routes, using monocyclic arene cis-dihydrodiols, and required no carbo
52 s of this method permits access to sensitive monocyclic arene oxides without any noticeable decomposi
53 to the Buchner reaction, which is limited to monocyclic arenes.
54 hesis and full characterization of the first monocyclic aromatic 1,2,3,5-tetrazine, 4,6-diphenyl-1,2,
55       In contrast to degradation pathways of monocyclic aromatic compounds where ring-cleavage is ach
56               cis-Dihydrodiols, derived from monocyclic aromatic compounds, are valuable chiral pool
57            In anaerobic microorganisms, most monocyclic aromatic growth substrates are converted to t
58 mixtures (mineral oil or crude oil), but not monocyclic aromatic hydrocarbons (MAHs) or polycyclic ar
59 n(II), and contaminating chemical compounds (monocyclic aromatic hydrocarbons such as phenolic or pol
60 ta for the OH radical-initiated reactions of monocyclic aromatic hydrocarbons, the reactions of OH-na
61  and conclusions from BN isosteres of simple monocyclic aromatic systems such as benzene and toluene
62           In addition to benzoic acid, other monocyclic aromatics (i.e., benzene, toluene, salicylic
63 t aromatics, shedding light on the fact that monocyclic aromatics can also serve as the hitherto unre
64  specific surfactants considered here, while monocyclic aromatics could, in some cases, negatively af
65                                        While monocyclic aromatics such as benzene were found to disru
66                                              Monocyclic as well as fused bicyclic systems with a nitr
67         In contrast to the photochemistry of monocyclic aza-cyclohexenones, their counterparts with a
68            Two of the most potent compounds, monocyclic azepinone 2n and bicyclic azepinone 3q, demon
69 d, thus enabling access to 2,2-disubstituted monocyclic azetidine scaffolds.
70 dvancements, successful reports of accessing monocyclic azetidines from acyclic imines remain scarce.
71 yrenes and dienes) to form 2,2-disubstituted monocyclic azetidines that can be further modified to re
72 ginal bicyclic tetrahydroquinoline core to a monocyclic benzylic-core system.
73 alosporins (ceftobiprole and ceftaroline), a monocyclic beta-lactam (BAL30072), the beta-lactamase in
74 nd G, a late step of the biosynthesis of the monocyclic beta-lactam antibiotic nocardicin A.
75              The nocardicins are a family of monocyclic beta-lactam antibiotics produced by the actin
76 cardicin A is the most potent of a series of monocyclic beta-lactam antibiotics produced by this orga
77 eart of nocardicin biosynthesis, a family of monocyclic beta-lactam antibiotics.
78  N(2)-(carboxyethyl)-L-arginine (CEA) to the monocyclic beta-lactam deoxyguanidinoproclavaminic acid
79                            Nocardicin A is a monocyclic beta-lactam isolated from the actinomycete No
80                            Nocardicin A is a monocyclic beta-lactam isolated from the actinomycete No
81  an enzyme that catalyzes the formation of a monocyclic beta-lactam ring in a similar ATP/Mg2+-depend
82 ase, an enzyme that catalyzes formation of a monocyclic beta-lactam ring with concomitant ATP hydroly
83  provide an attractive entry to a variety of monocyclic beta-lactam structures related to monobactams
84                                This class of monocyclic beta-lactams are stable to metallo-beta-lacta
85 bition of LDL-associated phospholipase A2 by monocyclic beta-lactams has shown that LDL phospholipase
86 mples illustrate the direct incorporation of monocyclic beta-lactams into a variety of molecular arch
87 l acetohydroxamates facilitated syntheses of monocyclic beta-lactams suitable for incorporation of a
88 ld CsF-induced N1 benzylation of alpha-azido monocyclic beta-lactams, the preparation of alpha-keto-b
89 L phospholipase A2 is capable of hydrolyzing monocyclic-beta-lactams by a mechanism which shares many
90                                  A series of monocyclic, bicyclic, and tricyclic aromatic compounds w
91 versible covalent drugs, we have synthesized monocyclic, bicyclic, and tricyclic compounds containing
92 1065 and the duocarmycins containing dimeric monocyclic, bicyclic, and tricyclic heteroaromatic repla
93 a family of inverse sandwich structures with monocyclic boron rings stabilized by two metal atoms.
94 ple gamma-lactone, gamma-lactam, and pyrrole monocyclic building blocks were designed and efficiently
95 eoselective preparation of chiral 4-membered monocyclic C2-substituted azetidines, where many routes
96  diverse sesquiterpenes, including humulene (monocyclic); caryophyllene (bicyclic); and protoilludene
97 ch the most commonly occurring types are the monocyclic chlorobactene and the dicyclic isorenieratene
98 PTDI) units: linear foldamers lin2 and lin4, monocyclic complement cyc2, and concatenated foldable ri
99                                            A monocyclic compound 3 (3-ethynyl-3-methyl-6-oxocyclohexa
100                                Among them, a monocyclic compound 5 is the most potent in these assays
101 he phosphoryl-enzyme complex formed from the monocyclic compound is significantly less mobile than th
102   Models of the noncovalent complexes of the monocyclic compound with the R61 DD-peptidase and a stru
103  the carbohydrates was a determinant for the monocyclic compounds of global activity patterns.
104                             Oxidation of the monocyclic compounds results in extrusion of the three h
105 aluation of a series of isoxazoles and other monocyclic compounds.
106 nzo[e][1,4]diazepin-3-yl]succin amic acid, a monocyclic conformationally constrained form of the tetr
107                                        Novel monocyclic cyanoenones examined to date display unique f
108                                        Among monocyclic cyanoenones, 1 is a highly reactive Michael a
109 of 26 was at least 10-fold less than that of monocyclic cyclo(1-3)[Ac-DAsp(1),DCpa(2),DLys(3),DNal(6)
110 experimental measurements of the energy of a monocyclic cyclobutadiene.
111                               In addition to monocyclic cyclopentenes, spirocyclic and bicyclic ones
112                            The corresponding monocyclic cyclopentenones are formed in good yields and
113                              Ten acyclic and monocyclic delta,epsilon-unsaturated ketones, with and w
114 ilon cyclase adds only one ring, forming the monocyclic delta-carotene (epsilon, psi-carotene), where
115 d-catalyzed condensation of tripyrranes with monocyclic dialdehydes, followed by an oxidation step.
116      Molecular dynamic behaviors of both the monocyclic dimer and the concatenated dimer-dimer ring w
117 h shows distinct stacking activities for the monocyclic dimer and the concatenated tetramer.
118 of P. simplex trail-following pheromone, the monocyclic diterpene neocembrene.
119 corresponding derivatives 7-10 (based on the monocyclic DMAP core).
120 f customizable diastereomeric cis- and trans-monocyclic enol-phosphonate analogs to Cyclophostin and
121 ) lipases suggests that these seven-membered monocyclic enol-phosphonates should provide useful leads
122                      Reactions of acyclic or monocyclic enolates generally lead to 1,2,3-triazoles bu
123 icular for the most challenging reactions of monocyclic, functionalized aryl bromides and triflates.
124  cyclization and ring contraction to furnish monocyclic gamma-presodorifen pyrophosphate (gamma-PSPP,
125                 Construction of the critical monocyclic guanidine has been achieved through two chann
126           We have previously reported that a monocyclic hAGRP(103-122) peptide is an antagonist at th
127 s, we report herein the preparation of novel monocyclic hemiboronic acids, diazaborines.
128 ccessing the triplet state of the ubiquitous monocyclic (hetero)arenes poses a formidable challenge d
129 ro)aromatic systems, while the more abundant monocyclic (hetero)arenes remain vastly underexplored.
130 reactivity relationships between substituted monocyclic heteroarenes and biradical acceptors, facilit
131 intermolecular dearomative cycloadditions of monocyclic heteroarenes with alkenes and bicyclo[1.1.0]b
132     Here we report the discovery of a simple monocyclic host that matches the earlier designs, but is
133                                          The monocyclic humulyl cation, the product of 11,1-cyclizati
134                                      Whereas monocyclic hydrocarbons evoked patterns similar to those
135  were exposed to sets of odorants, including monocyclic hydrocarbons, bicyclic compounds, and various
136 rrents as a measure of antiaromaticity among monocyclic hydrocarbons.
137 site double mutant fails to turn over, but a monocyclic hydroxyphenyl-thiazolinyl-cysteine (HPT-Cys)
138 centre, and proceeds through an enzyme-bound monocyclic intermediate.
139 (1H and 13C) NMR and found to be 14-membered monocyclic isocembrenyl diterpenes, indicating that the
140 een suggested to proceed through a series of monocyclic isocembrenyl- and bicyclic verticillyl-carboc
141                                              Monocyclic lactams are predicted to have amidicities at
142 eptide during the sequential biosynthesis of monocyclic lyciumin I via glycine-tryptophan crosslinkin
143                      The binding affinity of monocyclic [Lys13,Asp17]-(I) and bicyclic [Lys13,Asp17,L
144                                          The monocyclic macrocycle (1TMC) was also synthesized as a m
145              Here we report the first planar monocyclic metallaboron systems with Mobius aromaticity.
146           A scaffold hopping exercise from a monocyclic mGlu(2) NAM with poor rodent PK led to two no
147                                    Elongated monocyclic mimics show much longer residence time within
148 homology model for CYP2E1, the two sites for monocyclic molecules, pNP and 4MP, exist within a narrow
149 phenolic acid, were used in the synthesis of monocyclic mycophenolic acid analogues 2a-i.
150 However, this cyanobacterium also produces a monocyclic myxoxanthophyll, which was identified as myxo
151 o generate 11 conjugated double bonds in the monocyclic myxoxanthophyll.
152 esearch on aromaticity has mainly focused on monocyclic [n]annulene-like systems or polycyclic aromat
153 ncreased reactivity was observed relative to monocyclic NA.
154 ins/cephalosporins, the monobactams, and the monocyclic nocardicins, as well as the vancomycin family
155 attern as well as macrolide structure, e.g., monocyclic nonanolide core or bicyclic ring systems with
156 synthase transforms geranyl diphosphate to a monocyclic olefin and constitutes the simplest model for
157 -(crotonamido)quinoline-3-carbonitriles with monocyclic or bicyclic anilines.
158 tro-aldol pathway produces 1,3,6-triarylated monocyclic pentafulvenes as side products in yields of 9
159                                          The monocyclic peptides showed no activity in these assays.
160                    Cyclic peroxides, such as monocyclic peroxides and serial-cyclic peroxides, give a
161 e of hydroperoxides, bicyclic endoperoxides, monocyclic peroxides, and serial cyclic peroxides.
162 rings may afford higher affinity relative to monocyclic phenyl-based systems.
163 al/mol higher than those of the six-membered monocyclic phosphoester, 2-ethoxy-1,3,2-dioxaphosphinane
164 of the bicyclic tropane ring system with the monocyclic piperidine ring system or an acyclic aminoalk
165 ine 1 and N-methyl- and N-benzyl-substituted monocyclic polyamines 2 and 3 was studied.
166 erically pure ramelteon was developed from a monocyclic precursor with a 17% overall yield and a 97%
167 icyclic products (B) and their corresponding monocyclic precursors (M).
168                      Ophiofuranone A and the monocyclic precursors 4 were weakly active against micro
169 hing the fused, bicyclic system into a novel monocyclic pyrimidinone scaffold through our understandi
170                                          The monocyclic ring closure and the dimer-dimer ring concate
171 clusters of this size should exist as planar monocyclic rings.
172 y higher affinity compared to the [3.3.1] or monocyclic scaffolds, which could be attributed to bette
173 follows the order 11a > 11b > 15a > 1 in the monocyclic series, and 24a > 19a > 28ain the bicyclic se
174                             Derivatives with monocyclic side chains were selective against Mycobacter
175 xy-octosyl acid 2'-phosphate (AHOAP), into a monocyclic six-carbon product, aminohexuronic acid 2'-ph
176 l, the reaction cycle was interrupted at the monocyclic stage.
177  to intercept the cyclization cascade at the monocyclic stage.
178 no groups, a process frequently resulting in monocyclic structures.
179 d at very similar rates to the corresponding monocyclic substrate, that is, cyclopropylcarbinyl mesyl
180              Furthermore, the formation of a monocyclic sulphoxide product from ACmC is most simply e
181 vity that was comparable to an unconstrained monocyclic system.
182 ty, as introduced in 1965, usually refers to monocyclic systems with 4n pi electrons.
183  (NaX; X = anion) to make contact, and to be monocyclic to simplify analyses.
184 ctive monofluorination reaction to yield the monocyclic trans-substituted alpha-fluoro lactam product
185 or multiple amino acid modifications in this monocyclic truncated hAGRP sequence resulted in molecule

 
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