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1 dibutyl phthalate solution, both 1 and 2 are monomeric.
2 orthoacylated phenolates are suggested to be monomeric.
3 termini swap, whereas drug-bound AcCYP51 was monomeric.
4 replaced with Ala or Gly, respectively, are monomeric.
5 rhomboid transmembrane core is intrinsically monomeric.
8 ormation of stable complexes between PZP and monomeric Abeta or small soluble Abeta oligomers formed
9 , similarly to divalent metal ions, binds to monomeric Abeta peptide and efficiently modulates Abeta
10 regation, effectively reducing the available monomeric Abeta pool for incorporation into fibrils.
11 of specific interactions of metal ions with monomeric Abeta to their effects on bulk aggregation.
12 ested by the recovery of the amide-I band of monomeric Abeta, which is red-shifted by 26 cm(-1) when
13 mmetrical total synthesis was devised with a monomeric advanced intermediate as the key building bloc
14 ter guidelines in all regimes, and inorganic monomeric Al is projected to exceed the 15 mug L(-1) thr
15 anes gave a dark red solution from which the monomeric alanediyl :AlAr(iPr8) (2) was isolated in ca.
16 tripeptides consisting of homo/hetero chiral monomeric all-cis 5-arylpyrrolidine-2,4-dicarboxylate un
17 n polymorphs differentially bind to and seed monomeric alpha-Syn aggregation within neurons, thus aff
22 an be attributed to their ability to recruit monomeric alpha-synuclein and spread in vivo and hence c
23 was not detected at 18 months, only diffuse monomeric alpha-synuclein staining was observed at 4 yea
24 y to investigate the interaction kinetics of monomeric alpha-synuclein with surface-tethered vesicles
25 gs induced modest, progressive compaction of monomeric alpha-synuclein, preventing aggregation into a
30 ot that interacts with membrane when cRaf is monomeric and becomes part of the interface upon Raf dim
32 aphic structures of HsNudT16 in complex with monomeric and dimeric ADP-ribose in identifying the acti
33 easurement of the mass fraction remaining of monomeric and dimeric alpha-pinene oxidation products on
35 re, we report the engineering of a series of monomeric and dimeric designed ankyrin repeat proteins (
37 formed molecular dynamics simulations for 69 monomeric and dimeric lignin-related phenolics with 3 mo
38 e the stepwise folding from partially folded monomeric and dimeric MC subunits (in chloroform) up to
39 ly, taking the different lateral mobility of monomeric and dimeric molecular species into account.
43 We present an ADM-based mixture model for monomeric and dimeric TF-binding motifs and an expectati
44 nd were associated with upregulation of both monomeric and dimerized forms of protein kinase G and of
45 ly and tightly bind the toxic oligomers over monomeric and fibrillar forms of Abeta, leading to inhib
47 se-grained molecular dynamics simulations of monomeric and filamentous actin in the vicinity of diffe
49 75,000 structurally unique junctions between monomeric and homo-oligomeric de novo designed and ankyr
51 nance energy transfer technique we show that monomeric and oligomeric alpha-syn affect G4Qs and i-mot
52 tion in recombination, we speculate that the monomeric and oligomeric forms of BRCA2 might be active
54 nd disordered domains, and that can populate monomeric and oligomeric states under physiological cond
55 clude molecular dynamics simulations of both monomeric and pentameric Abeta, which demonstrate decrea
56 this type may act like an assembly line for monomeric and small oligomeric subunits of Abeta to incr
57 However, the chaperone activity released monomeric and small oligomeric Tau species, which induce
59 utralizing mAb in vitro Binding studies with monomeric and trimeric hMPV F revealed that MPV364 had t
63 f both PVL and alpha-toxin in their soluble, monomeric, and oligomeric membrane-inserted pore states
64 4 experimentally tested designs were folded, monomeric, and stable, while the 2 determined structures
65 sponses considered for the optimization were monomeric anthocyanin content, antioxidant activity and
67 ing temperature reduced ascorbic acid, total monomeric anthocyanins (TMA) and total phenolics (TP) in
70 ](2+) clusters are transferred from GLRX3 to monomeric apo NUBP1 and reductively coupled to form [4Fe
71 g like wild type, demonstrating that in vivo monomeric arrestin-1 is necessary and sufficient for thi
73 entifying aggregation prone conformations of monomeric aSyn and the environmental conditions they for
75 lcium ion to investigate the conformation of monomeric aSyn in relation to its aggregation propensity
78 studies revealed that oligomerized, but not monomeric, beta-arrestin2 increases tau by inhibiting se
79 ylcholine, have the highest GB of any small, monomeric biomolecules measured to date and are more bas
80 imeric helical bundle was reconnected into a monomeric building block, and the surface was redesigned
82 We show VSV P lacking the OD (P(DeltaOD)) is monomeric but is indistinguishable from wild-type P in s
83 expressed and isolated and also shown to be monomeric by native MS, and addition of PS or PE to this
86 ng binding site in the trimeric interface of monomeric CD40L and generate integrin-CD40L-CD40 ternary
88 stalline materials where larger species than monomeric chemical constituents, i.e., ions or single mo
89 The external surfaces of the wedges link the monomeric complexes together into the dimeric structures
90 XS data with X-ray crystal structures of the monomeric component, we could generate a pseudo-atomic s
93 ly esterified, amorphous, and have a typical monomeric composition as demonstrated by solid-state NMR
94 indicate that additional factors beyond the monomeric composition of native lignin are important in
95 he interconversion between the major twisted-monomeric conformation and a more regular beta strand co
100 e (VCAM) protein levels by ~50%, whereas the monomeric D73K mutant reduced VCAM by 90% at the same co
101 uld suggest, a dimeric methyltransferase and monomeric demethylase cooperate to eliminate asymmetry a
102 ng purified recombinant DDR2 ECD proteins in monomeric, dimeric or oligomeric state, and MC3T3-E1 cel
103 of a series of designed analogues possessing monomeric, dimeric, trimeric, and tetrameric macrocyclic
106 tegy to efficiently refold two high-yielding monomeric E2 species, D123 and a disulfide-minimized ver
107 ociation may compensate for the inability of monomeric E2A-PBX1 to stably bind DNA and circumvents pr
108 unctioning before the slower one, and in the monomeric enzyme, the active sites also perform single-r
109 ed pluripotent stem cells (iPSCs) and used a monomeric Fc-ligand fusion platform to steer the ligand
111 o role in histone chaperoning and revealed a monomeric five-beta palm-like fold that wrapped over a h
112 roanthocyanidin polymerization and decreased monomeric flavan-3-ols, which may reduce wine bitterness
113 The cryo-electron microscopy structure of monomeric FluPol(A) bound to the cRNA template reveals a
116 (catalytically competent form), whereas the monomeric form absorbed at 420 nm (catalytically incompe
117 oid formation by maintaining alphaSyn in its monomeric form and that they are non-cytotoxic despite r
118 t 1) phosphorylation of Rad54 stabilizes the monomeric form by reducing the interlobe movement of Rad
119 protomers per homo-oligomer), but it was the monomeric form of all micropeptides that interacted with
123 lated, which initiates a switch to a dimeric/monomeric form that translocates into the nucleus, causi
124 Rs are capable of activating G proteins in a monomeric form, they can also potentially assemble into
125 Using a variant that exists mainly in a monomeric form, we report the solution structure of an H
126 ons TMX2 occurs in both reduced and oxidized monomeric form, while it forms a stable dimer under trea
129 tion of oligomers was observed for PrPC when monomeric fractions derived from size exclusion chromato
130 t for catalyzing C-to-U RNA editing in vitro Monomeric fractions possessed the highest conversion eff
132 at the calcium-channel inhibitor Rad(8,9), a monomeric G protein, is enriched in the Ca(V)1.2 microen
133 f these compounds affected the transition of monomeric G-actin to filamentous F-actin, and that sever
134 B (TcdB), glucosyltransferases that modulate monomeric G-protein function and alter cytoskeletal func
135 human telomeric G-quadruplex multimers over monomeric G-quadruplexes with high selectivity, and indu
136 he N-terminus (the branched architecture) or monomeric GalNAc moieties anchored at C(gamma) of three
137 ociates Galphai*betagamma trimers, scaffolds monomeric Galphai with RTKs, and facilitates the phospho
138 GOR is phylogenetically distinct from the monomeric GAP-oxidizing enzyme found previously in sever
139 nase enzymes processively excise and package monomeric genomes from a concatemeric DNA substrate.
140 ted in all of the dsDNA viruses that package monomeric genomes from concatemeric DNA substrates and t
147 7A induced the recruitment of Rab35 (a small monomeric GTPase) and DennD1C (guanine nucleotide exchan
148 cs of the actin cytoskeleton, and the small, monomeric GTPases Rac and Rho are important regulators o
149 ed under the assumption that Zn(2+) binds to monomeric H(V)1 despite evidence that H(V)1 expresses as
150 d on several timescales, show that leptin is monomeric, has a rigid four-helix scaffold, and a dynami
151 redicts that after autoxidation, dimeric and monomeric hemichrome intermediates occur along the disas
154 n the brace helix region revealing a form of monomeric hMLKL necessary for oligomerization upon phosp
155 MPV364 had the weakest binding affinity for monomeric hMPV F compared to the other three mAbs, yet b
156 ticular five-coordinate species is the first monomeric, homoleptic, all-oxygen-ligated but non-oxo 4d
157 rmal growth factor receptor 2 (HER2)-binding monomeric IgA1, IgA2m(1), and IgA2m(2) variants in Nicot
158 hrough the rapid coalescence of pre-existing monomeric IgG1 nuclei into a dead-end aggregate, rather
160 s, CaiT-D288A and -D288R proved to be mostly monomeric in detergent solution and after reconstitution
162 oniae and Mycobacterium tuberculosis AtaC is monomeric in solution and binds Mn(2+) to specifically h
168 ulatory domain of R68S PheH is predominantly monomeric in the absence of phenylalanine and dimerizes
171 domain (IRE1(LD)) that favours the latter's monomeric inactive state and loss of ERdj4 de-represses
175 ulfide bonds, as well as in cells expressing monomeric ITAM or hemITAM gamma-chimeras, support model
176 holerae, where the fluorescent protein (mKO; monomeric Kusabira Orange) and bacterial cells show char
177 In this study, we explore the recognition of monomeric Le(x) by IG5F6 using a panel of Le(x) analogue
178 e a higher affinity for polymeric Le(x) over monomeric Le(x) In this study, we explore the recognitio
179 le to proteolytical cleavage, resulting in a monomeric ligand (ANGPT2(DAP)) that inhibited ANGPT1- or
180 e present work, we further characterized the monomeric LPL/GPIHBP1 complex and its derivative, the LP
181 r, high-resolution structures of full-length monomeric M1 and the matrix layer have not been availabl
183 lopodia tip complexes, and overexpression of monomeric, membrane--targeted lamellipodin mutants disru
188 terials for the synthesis of three iodinated monomeric moieties (a modified lactide, morpholine-2,5-d
189 t a resolution of 2.59 angstrom, revealing a monomeric molecule that is structurally distinct from al
191 ographic maps for a representative subset of monomeric, monoligated palladium complexes allowed us to
192 obutane rings and have recently been used as monomeric motifs to develop polymers that drastically ch
193 ed and unique features of RNA synthesis, the monomeric multifunctional enzyme L, and the oligomeric m
194 McH3H was found to be a single component monomeric NAD(P)H-dependent FAD-containing monooxygenase
195 (rate constant k(3)), where A represents the monomeric nanoparticle precursor, B represents "small" n
196 n in vitro had proved challenging due to its monomeric nature in the absence of the transmembrane dom
199 phil gelatinase-associated lipocalin (NGAL), monomeric NGAL (mNGAL), interleukin-18, and standard bio
201 ational design to engineer a complete set of monomeric NIR FPs, which are the brightest genetically e
203 e utilized to functionalize or to cross-link monomeric nucleosides or DNA for diagnostic or imaging p
206 en trimeric forms were used as compared with monomeric or dimeric forms, we investigated the extent t
207 onstruct, htt(NT)Q(7), which remains largely monomeric over a sufficiently long period of time to per
208 strom resolution, revealing a single-domain, monomeric parallel beta-helix containing a 10-step aspar
209 rmented and dried cocoa had higher levels of monomeric phenols, methylxanthines, phenylethylamine and
210 stoichiometric hydrogen acceptor to release monomeric phosphinoboranes, [RR'PBH(2)], under mild cond
211 e polyphenols, including up to 50 individual monomeric pigments together with fingerprints of three d
213 ng protein also catalyzes oligomerization of monomeric portal protein into dodecameric rings, possibl
215 hat vesicular synaptobrevin-2 (syb-2) in its monomeric prefusion conformation shows high flexibility,
216 2)-macroglobulin-like protein 1 (A2ML1) is a monomeric protease inhibitor but has the hydroxyl reacti
217 protein evolution, we previously tailored a monomeric protein (cyt cb(562) ) for metal-mediated self
219 sign is based on the hyper-stable, naturally monomeric protein CI2, a paradigm of simple two-state fo
220 erver, AWSEM-Suite, whose goal is to predict monomeric protein tertiary structures from sequence is d
221 ite server is a powerful tool for predicting monomeric protein tertiary structures that is most usefu
225 In vitro exchange assays were done with monomeric proteins, although ARF-GEFs form dimers in viv
227 hin the molecular weight range approximating monomeric PrP (mM1000) generated through size exclusion
232 omains are similar in structure to two other monomeric restriction enzymes, HinP1I (G CGC) and MspI (
236 core protected by a ligand shell made of 24 monomeric [-S-Au-S-] and 6 dimeric [-S-Au-S-Au-S-] stapl
238 tely mimics HIV-1 target cells compared with monomeric sCD4 and dimeric CD4-Ig, we generated virus-li
239 sical and in vitro analyses demonstrate that monomeric semaphorins can mediate a distinctive plexin b
241 We performed six rounds of selection for monomeric sequences and show that the enriched populatio
243 ACalpha, resulting in PP2A activation, while monomeric SET remained associated with the B56gamma.
246 le of symmetry breaking, which alongside the monomeric small GTPases provides a core mechanism for th
247 l that allows the generation of a homogenous monomeric solution of GNNQQNY to uncover the molecular d
248 ctral characteristics in the crystalline and monomeric solution state for 6,13-bisaryl-substituted pe
250 , the nature of the interactions between the monomeric species and the fibrils during this key proces
251 strength in the absence of polyanions; only monomeric species are observed, and the extent of multip
252 re the formation of these soluble oligomers, monomeric species first adopt aggregation-competent conf
253 m, we detect the disappearance of the native monomeric species, formation of a partially unfolded int
254 fferentiating multimeric G-quadruplexes over monomeric species, which would be able to form in the si
255 m between a catalytically active dimer and a monomeric species, with the latter being inactive and pr
259 The thiol rHSA variants exhibited up to 95% monomeric stability over 24 months and retained hFcRn en
260 tion, we find that enhanced diffusion in the monomeric state coupled to reassociation into the functi
261 effective brightness in mammalian cells and monomeric state, perform well in both nanometer-scale im
265 , SIP, near-native poses of 7 HoTPs in their monomeric states can be correctly identified in the top-
267 -dipyridyl anchoring ligand can maintain the monomeric structure of catalyst and gives relatively sta
269 ned that purification of the nonaggregating, monomeric subpopulation of a random-sequence RNA pool wi
272 hedral angles between the constituent planar monomeric subunits or those with overall planarity, refe
273 ion patterns of the LHCII trimers and of the monomeric subunits were affected in the phosphatase muta
276 in T cell-mediated target cell-killing, and monomeric teal fluorescent protein from the endogenous G
277 cal predictions of the VCD, ECD, and ORD for monomeric tert-butylphenylphosphinoamidate were carried
278 ntrast to simple organolithium reagents, the monomeric THF-solvate was found to be more stable than t
279 nd assembly domain of TNFR1 resulted in only monomeric TNFR1, which exhibited impaired ligand binding
280 nstrate that, under reducing conditions, the monomeric Tom1 VHS domain switches from a three-state to
281 imulations to probe conformations sampled by monomeric transthyretin under amyloidogenic conditions.
284 etric inhibition by interacting not with the monomeric unfolded conformations of the amyloid-beta sym
285 he total synthesis of the fully glycosylated monomeric unit of lomaiviticin A, monolomaiviticin A.
286 c member chilocorine C possesses an alluring monomeric unit that combines quinolizidine and indolizid
287 sly shown to exhibit chirality transfer from monomeric unit to the multichain domain morphology.
288 ntrosymmetric dimers in the crystal with the monomeric units linked by C=O...H...N bifurcated hydroge
290 itive polaron in the polymer over about four monomeric units, corresponding to about 45 angstrom in l
295 These findings suggest the interplay between monomeric vs dimeric states has a hereto unappreciated r
296 ll as a discussion of physical properties of monomeric vs engineered heterodimeric degraders are pres
299 are consistent with a working model in which monomeric XPA bends DNA, displays episodic phases of lin