ライフサイエンスコーパス: mononucleotide

1 uding the analytically most demanding flavin mononucleotide.

2 tivity and of the NAMPT product nicotinamide mononucleotide.

3 elease pyrophosphate (PP(i)) or nicotinamide mononucleotide.

4 res an unprecedented binding site for flavin mononucleotide.

5 a result that was reversed with nicotinamide mononucleotide.

6 s: anthraquinone-2,6-disulphonate and flavin mononucleotide.

7 g coupled to binding of its cofactor, flavin mononucleotide.

8 instead convert nicotinamide to nicotinamide mononucleotide.

9 milk was the richest source of nicotinamide mononucleotide.

10 ectrolyte based on the sodium salt of flavin mononucleotide.

11 nt to enhance the water solubility of flavin mononucleotide.

12 the low efficiency of template copying with mononucleotides.

13 esponsible for dephosphorylation of pyridine mononucleotides.

14 e remaining complementary single strand into mononucleotides.

15 erative manner and with lower affinity, like mononucleotides.

16 oxidases, this enzyme contains haem, flavin mononucleotide, 2Fe-2S and tetrahydrofolic acid cofactor

17 hat three yeast enzymes possess nicotinamide mononucleotide 5'-nucleotidase activity in vitro.

18 mutant P4 enzyme complexed with nicotinamide mononucleotide, 5'-AMP, 3'-AMP, and 2'-AMP.

19 Listeria genomes lack CobT, the nicotinamide mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphori

20 er ([4Fe-4S](2+)) and a 6-S-cysteinyl flavin mononucleotide (6-S-Cys-FMN) as redox cofactors.

21 are presented to demonstrate its utility: a mononucleotide (A) microsatellite at the BAT-26 locus an

22 Here we show that the flavin mononucleotide, a common redox cofactor, wraps around si

23 ting potential-induced changes in the flavin mononucleotide active site of a flavoenzyme.

24 They are comprised of two mononucleotides, adenosine monophosphate and nicotinamid

25 w: the NAD+ biosynthetic enzyme nicotinamide mononucleotide adenyltransferase (Nmnat), which acts in

26 in the first intron of Nmnat2 (Nicotinamide mononucleotide adenyltransferase 2).

27 ld(S)) encodes a chimeric Ube4b/nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1) fusion pr

28 of the NAD synthesizing enzyme nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1) has been

29 de (NAD(+)) biosynthetic enzyme nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1).

30 inucleotide-synthesizing enzyme nicotinamide mononucleotide adenylyl transferase 1.

31 Nicotinamide mononucleotide adenylyl transferase 2 (NMNAT2) is a key

32 Nicotinamide mononucleotide adenylyl transferase 2 (NMNAT2) is neurop

33 NAD(+) synthesis enzyme Nmnat (nicotinamide mononucleotide adenylyl transferase), but requires the c

34 nce and protective function for nicotinamide mononucleotide adenylyl transferases (NMNATs).

35 operates at the level of the nicotinic acid mononucleotide adenylyl-transferase Nma1 and can be bypa

36 Flavin mononucleotide adenylyltransferase (FMNAT) catalyzes the

37 the last steps of NAD biogenesis, nicotinate mononucleotide adenylyltransferase (NadD) and NAD synthe

38 This reaction is catalyzed by nicotinate mononucleotide adenylyltransferase (NMAT), which is esse

39 reased levels of nicotinamide/nicotinic acid mononucleotide adenylyltransferase (NMNAT) act as a powe

40 tective effects of NAD synthase nicotinamide mononucleotide adenylyltransferase (NMNAT) against activ

41 salvage pathway, constituted by nicotinamide mononucleotide adenylyltransferase (NMNAT) and nicotinam

42 ies on the NAD synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT) have uncovere

43 Nicotinamide mononucleotide adenylyltransferase (NMNAT) is a conserve

44 e associated with a decrease in nicotinamide mononucleotide adenylyltransferase (Nmnat) protein level

45 Overexpression of nicotinamide mononucleotide adenylyltransferase (Nmnat), a component

46 Importantly, nicotinamide mononucleotide adenylyltransferase (NMNAT), an evolution

47 indicates that it is a putative nicotinamide mononucleotide adenylyltransferase (NMNAT).

48 otective function of Wld(S) and nicotinamide mononucleotide adenylyltransferase (Nmnat).

49 nuclear NAD(+) synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) is frequentl

50 oribosyltransferase (NAMPT) and nicotinamide mononucleotide adenylyltransferase 1 (NMNAT-1) constitut

51 full-length coding sequence of nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1), which alo

52 The NAD-synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) is a criti

53 Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) is an endo

54 A and protein levels of NMNAT2 (nicotinamide mononucleotide adenylyltransferase 2), a recently identi

55 Bacterial nicotinate mononucleotide adenylyltransferase encoded by the essent

56 NAD(+), the metabolite of WldS/nicotinamide mononucleotide adenylyltransferase enzymatic activity, i

57 Nicotinate mononucleotide adenylyltransferase NadD is an essential

58 uding inhibition by both NMNAT (nicotinamide mononucleotide adenylyltransferase) expression and loss

59 encodes the nuclear isoform of nicotinamide mononucleotide adenylyltransferase, a rate-limiting enzy

60 Nicotinamide mononucleotide adenylytransferase (NMNAT) is a neuroprot

61 trations of 3MI and 6MI in solution with the mononucleotides AMP, CMP, GMP, and TMP.

62 as minimized by the addition of nicotinamide mononucleotide, an inhibitor of NAD(+) glycohydrolases.

63 adenylyl transferase condenses nicotinamide mononucleotide and (tz) ATP to yield N(tz) AD(+) , which

64 The hydrophilic matrix arm comprises flavin mononucleotide and 8 iron-sulfur clusters involved in el

65 on analysis (NCA) method was used to compare mononucleotide and dinucleotide frequencies for RNA viru

66 examine these interactions, including simple mononucleotide and dinucleotide position weight matrix m

67 High levels of MSI at mononucleotide and dinucleotide repeats in colorectal ca

68 the precursor of the flavin coenzymes flavin mononucleotide and flavin adenine dinucleotide.

69 ough its conversion to coenzyme forms flavin mononucleotide and flavin adenine dinucleotide.

70 roduction in the mitochondria include flavin mononucleotide and flavin mononucleotide-binding domain

71 ation of nicotinamide riboside, nicotinamide mononucleotide and NAD in milk by means of a fluorometri

72 tion with the NAD(+) precursors nicotinamide mononucleotide and nicotinamide riboside also increases

73 The NAD biosynthetic precursors nicotinamide mononucleotide and nicotinamide riboside are reported to

74 osphorylate the mononucleotides nicotinamide mononucleotide and nicotinic acid mononucleotide (NAMN)

75 deamidation steps leading to nicotinic acid mononucleotide and nicotinic acid riboside production ar

76 entric pi-pi interactions between the flavin mononucleotide and the underlying graphene wall.

77 lity (MSI) analysis using 5 highly sensitive mononucleotides and 2 pentanucleotides was performed.

78 xoribonuclease on some substrates, releasing mononucleotides and a ladder of digestion products.

79 ively digests the 5'-ended strand to form 5' mononucleotides and a long 3' overhang.

80 d efficient enzymes that hydrolyze RNA to 3' mononucleotides and also possess antitumorigenic and ant

81 In order to study condensation products of mononucleotides and hydrolysis of their polymers, we est

82 which demonstrates that low-molecular-weight mononucleotides and simple cationic peptides spontaneous

83 ydrolysis, explain the low reaction rates of mononucleotides and suggest two distinct mechanisms for

84 in perfusate (eg, lactate, succinate, flavin mononucleotide) and tissues (eg, succinate, adenosine tr

85 es, adenosine monophosphate and nicotinamide mononucleotide, and are present as oxidized and reduced

86 rent subunits, a non-covalently bound flavin mononucleotide, and eight iron-sulfur clusters.

87 If 5'-mononucleotides are in solution at millimolar concentrat

88 eotide, thus enabling discrimination against mononucleotides as substrates.

89 significantly higher affinity of the flavin mononucleotide assembly for (8,6)-single-walled carbon n

90 In the presence of a surfactant, the flavin mononucleotide assembly is disrupted and replaced withou

91 The strength of the helical flavin mononucleotide assembly is strongly dependent on nanotub

92 he second method analyzes nuclease-generated mononucleotides before and after treatment with base or

93 e change (R116Q), predicted to affect flavin mononucleotide binding and binding of the two PNPO dimer

94 e intermediate and, together with the flavin mononucleotide binding cradle, we propose a novel cataly

95 We have defined a novel flavin mononucleotide binding cradle, which is a recurrent moti

96 For tight and specific binding to the eIF4E mononucleotide binding site, there seems to be a clear r

97 ng interaction between the cap and the eIF4E mononucleotide binding site.

98 This correlated with loss of flavin mononucleotide binding.

99 gene XC_0249 encodes a protein with a cyclic mononucleotide-binding (cNMP) domain and a GGDEF diguany

100 a bacterial monooxygenase, contains a flavin mononucleotide-binding domain bearing a strong structura

101 ria include flavin mononucleotide and flavin mononucleotide-binding domain of complex I, ubisemiquino

102 Using flavin mononucleotide-binding proteins and glycosidases as exam

103 precursor that is converted to nicotinamide mononucleotide by specific nicotinamide riboside kinases

104 red in equimolar mixtures of the constituent mononucleotides by one to two orders of magnitude, indic

105 Furthermore, if the mononucleotides can form complementary base pairs, then

106 eaction to form the NAD precursor nicotinate mononucleotide, carbon dioxide, and pyrophosphate from q

107 Per-Arnt-Sim (PAS) family, contains a flavin mononucleotide chromophore that forms a covalent bond wi

108 1), non-interacting pH-sensitive polypeptide/mononucleotide coacervate droplets containing proteinase

109 entation and contraction of the bound flavin mononucleotide cofactor and cleavage of the ribityl tail

110 pong type mechanism, catalyzed by the flavin mononucleotide cofactor in the active site for NADH oxid

111 d proteins, iron-sulfur clusters, and flavin mononucleotide cofactor require the participation of ass

112 aromatic compounds using a prenylated flavin mononucleotide cofactor.

113 the formation of dead-end prenylated flavin mononucleotide cycloadducts occurs with distinct propeno

114 e C-terminal domain harbors the nicotinamide mononucleotide deamidase activity, and the structure of

115 CinA was shown to have both nicotinamide mononucleotide deamidase and ADP-ribose pyrophosphatase

116 tionships of the functionally diverse flavin mononucleotide-dependent nitroreductase (NTR) superfamil

117 A nicotinic acid mononucleotide derivative is tethered to Lys(184) and fo

118 tes at reporter cassettes containing defined mononucleotide, dinucleotide, and tetranucleotide micros

119 ts (STRs) with individual motifs composed of mononucleotides, dinucleotides or higher including hexam

120 any cofactors of enzymatic processes such as mononucleotides (e.g. ADP, ATP, GTP), dinucleotide cofac

121 ding a methylene blue-labeled electro-active mononucleotide (eNT).

122 The most frequent mutation, a mononucleotide expansion from a polyA repeat tract (c.13

123 that an aliphatic (dodecyl) analog of flavin mononucleotide, FC12, leads to high dispersion of SWNTs,

124 e MtrC from Shewanella oneidensis and flavin mononucleotide (FMN in fully oxidized quinone form) usin

125 contain a distinctive non-heme diiron/flavin mononucleotide (FMN) active site.

126 egulated (LOV1 and LOV2) domains bind flavin mononucleotide (FMN) and activate the phototropism photo

127 avin (vitamin B2) is the precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide, wh

128 flavin-dependent enzyme that converts flavin mononucleotide (FMN) and glutamate to 8-amino-FMN via th

129 Protein ligands of the flavin mononucleotide (FMN) and the plant-type [2Fe-2S] cluster

130 ne biosynthesis pathway and harbors a flavin mononucleotide (FMN) as a potential cofactor.

131 which contains a non-covalently bound flavin mononucleotide (FMN) as cofactor, acquires its native al

132 ure of V. harveyi luciferase bound to flavin mononucleotide (FMN) at 2.3 A.

133 The crystal structure reveals an flavin mononucleotide (FMN) binding site unique from all other

134 own to involve formation of a triplet flavin mononucleotide (FMN) chromophore followed by the appeara

135 teine residue and an internally bound flavin mononucleotide (FMN) chromophore.

136 constraints in the environment of the flavin mononucleotide (FMN) chromophore; in iLOV, the methyl gr

137 urprisingly, IDI-2 requires a reduced flavin mononucleotide (FMN) coenzyme to carry out this redox ne

138 R) where the protein and/or intrinsic flavin mononucleotide (FMN) cofactor are isotopically labeled w

139 lent attachment of an analogue of the flavin mononucleotide (FMN) cofactor onto carboxylic functional

140 diiron-carboxylate site proximal to a flavin mononucleotide (FMN) cofactor.

141 mmediately after turnover with NO are flavin mononucleotide (FMN) dependent, implicating an additiona

142 The redox potential of the flavin mononucleotide (FMN) hydroquinones for one-electron redu

143 to a large increase in the amount of flavin mononucleotide (FMN) in the E. coli cell extract.

144 e chiral D-ribityl phosphate chain of flavin mononucleotide (FMN) induces a right-handed helix that e

145 ween electrostatic plus van der Waals flavin mononucleotide (FMN) interdigitation and H-bonding inter

146 y the photo-induced transformation of flavin mononucleotide (FMN) into lumichrome, which increases th

147 Flavin mononucleotide (FMN) is a coenzyme for numerous proteins

148 o the flavodoxin superfamily in which flavin mononucleotide (FMN) is firmly anchored to the protein.

149 active site with two adjacently bound flavin mononucleotide (FMN) ligands, one deeply buried and tigh

150 plant-type [2Fe-2S] cluster, and one flavin mononucleotide (FMN) per enzyme.

151 c hydrocarbons by a phosphate-bearing flavin mononucleotide (FMN) photocatalyst on high surface area

152 The flavin mononucleotide (FMN) quinones in flavodoxin have two cha

153 e of the disulfide in the presence of flavin mononucleotide (FMN) resulted in the reversible formatio

154 tibiotic Ribocil C, which targets the flavin mononucleotide (FMN) riboswitch, from a compound lacking

155 Flavin mononucleotide (FMN) riboswitches are genetic elements,

156 The flavin mononucleotide (FMN) serves as the one-electron donor to

157 The IET from the flavin mononucleotide (FMN) to heme domains is essential in the

158 erdomain electron transfer (IET) from flavin mononucleotide (FMN) to heme is essential in nitric oxid

159 no acid, additional members of a rare flavin mononucleotide (FMN) variant class, and also variants of

160 phate (PLP), folate, vitamin B12, and flavin mononucleotide (FMN) were measured for all subjects.

161 ity capable of reducing either FAD or flavin mononucleotide (FMN) with NADH as the reductant.

162 DH, the primary acceptor of electrons flavin mononucleotide (FMN), and a chain of seven iron-sulfur c

163 flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), are two key cofactors involved in

164 ons flavins, including riboflavin and flavin mononucleotide (FMN), into the surrounding medium to act

165 flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), the physiologically relevant catal

166 is oxidized by a noncovalently bound flavin mononucleotide (FMN), then seven iron-sulfur clusters tr

167 V2 protein that binds the chromophore flavin mononucleotide (FMN), we have developed a promising phot

168 for NO production is a complex of the flavin mononucleotide (FMN)-binding domain and the heme domain,

169 hemical characterization of UbiX as a flavin mononucleotide (FMN)-binding protein, no decarboxylase a

170 he Acg family turns out to be unusual flavin mononucleotide (FMN)-binding proteins that have probably

171 Prior evidence indicated the flavin mononucleotide (FMN)-binding riboswitch aptamer adopted

172 analysis revealed the presence of one flavin mononucleotide (FMN)-binding site and two iron-sulfur cl

173 yl diphosphate isomerase (IDI-2) is a flavin mononucleotide (FMN)-dependent enzyme that catalyzes the

174 (PLP)-dependent enzyme (Fub7), and a flavin mononucleotide (FMN)-dependent oxidase (Fub9) in synthes

175 of unknown function, and a paucity of flavin mononucleotide (FMN)-dependent proteins in these familie

176 Flavin mononucleotide (FMN)-specific riboswitches, also known a

177 d one molecule of noncovalently bound flavin mononucleotide (FMN).

178 e gut microbial GUS enzymes that bind flavin mononucleotide (FMN).

179 sis of released mitochondrial flavin (flavin mononucleotide, FMN) in the machine perfusate.

180 o have decreased affinity for reduced flavin mononucleotide (FMNH(2)).

181 ecifically interacts with the reduced flavin mononucleotide (FMNH2) and that FMNH2 can quickly reduce

182 The reduced flavin mononucleotide (FMNH2) generated by FRP must be supplied

183 oop are governed by binding of either flavin mononucleotide (FMNH2) or polyvalent anions.

184 .0, 7.0) containing a reduced form of flavin mononucleotide (FMNH2, 100 muM), a biogenic soluble elec

185 ficiently competing with the adenine/guanine mononucleotides for the allosteric sites.

186 st and catalyzes the formation of nicotinate mononucleotide from quinolinate and 5-phosphoribosyl-1-p

187 riminatory short sequence repeat loci, i.e., mononucleotide G and trinucleotide GGT, in isolates from

188 B3, and its phosphorylated form nicotinamide mononucleotide, have been shown to be potent supplements

189 he redox reaction kinetics of reduced flavin mononucleotide (i.e., FMNH(2)) and reduced riboflavin (i

190 e DNA sequencing strategies that employ free mononucleotide identification.

191 Alternatively, NADH oxidation, by the flavin mononucleotide in complex I, can be coupled to the reduc

192 nicotinamide adenine dinucleotide to flavin mononucleotide in morphinone reductase proceeds via envi

193 , triggering the digestion of the probe into mononucleotides including a methylene blue-labeled elect

194 for residues near the surface of the flavin mononucleotide, including 87-90 (loop 1), and for key CY

195 ain; it comprises NADH oxidation by a flavin mononucleotide, intramolecular electron transfer along a

196 ic organisms, and its requirement for flavin mononucleotide is even more uncommon in catalysis.

197 During catalysis, NADH oxidation by a flavin mononucleotide is followed by electron transfer to a cha

198 Selection is detectable even at the mononucleotide level, so that the asymmetric base compos

199 crosatellite status using the five different mononucleotide markers BAT25, BAT26, NR-21, NR-22 and NR

200 ate experimentally that both the length of a mononucleotide microsatellite and its sequence context i

201 on start site density, H3K4me1 coverage, and mononucleotide microsatellite coverage are significant p

202 ion-deletion (indel) rates observed in short mononucleotide microsatellites (here referred to as poly

203 Fourth, mutability of mononucleotide microsatellites is impacted by their loca

204 rectal cancers revealed indels at 54 million mononucleotide microsatellites of three or more nucleoti

205 c background mutation rate in protein-coding mononucleotide microsatellites, allowing a full catalogi

206 ains modulate ROS production from the flavin mononucleotide moiety and iron-sulfur clusters.

207 ce repeats, the most abundant (47.8 %) being mononucleotide motifs.

208 ed neuronal maintenance factor, nicotinamide mononucleotide (NAD) adenylyl transferase (NMNAT), a pro

209 onds to depletion of cellular nicotinic acid mononucleotide (NaMN) and mediates nicotinamide mononucl

210 cotinamide mononucleotide and nicotinic acid mononucleotide (NAMN) and thus catalyze NR and NAR forma

211 ase (QAPRTase, EC 2.4.2.19) forms nicotinate mononucleotide (NAMN) from quinolinic acid (QA) and 5-ph

212 lyze the adenylylation of the nicotinic acid mononucleotide (NaMN) precursor to nicotinic acid dinucl

213 sfers the phosphoribosyl group of nicotinate mononucleotide (NaMN) to phenol or p-cresol, yielding al

214 t the point where the reaction of nicotinate mononucleotide (NaMN) with ATP is coupled to the formati

215 NadD substrates, i.e. ATP and nicotinic acid mononucleotide (NaMN).

216 robes, alpha-RP is synthesized by nicotinate mononucleotide (NaMN):DMB phosphoribosyltransferases (Co

217 A redox flow battery using flavin mononucleotide negative and ferrocyanide positive electr

218 -III, but not CN-IA, can dephosphorylate the mononucleotides nicotinamide mononucleotide and nicotini

219 inic acid adenine dinucleotide, nicotinamide mononucleotide, nicotinic acid, or nicotinamide.

220 Nicotinamide mononucleotide (NMN) adenylyltransferase 2 (Nmnat2) cata

221 zes the reversible synthesis of nicotinamide mononucleotide (NMN) and inorganic pyrophosphate (PP i)

222 uding striking accumulations of nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) in t

223 ar NAD(+) or NAD(+) precursors, nicotinamide mononucleotide (NMN) and NR, can reverse the FK866-induc

224 hown that the NAD(+) precursor, nicotinamide mononucleotide (NMN) can reverse some of the negative co

225 onucleotide (NaMN) and mediates nicotinamide mononucleotide (NMN) catabolism, thereby contributing to

226 nistration of NAD(+) precursor, nicotinamide mononucleotide (NMN) extended lifespan of Ndufs4-KO mice

227 cture for pyrophosphorolysis of nicotinamide mononucleotide (NMN) from kinetic isotope effects (KIEs)

228 expression of bacterial nicotinamide adenine mononucleotide (NMN) in zebrafish and mice, which decrea

229 mice with the NAD(+) precursor nicotinamide mononucleotide (NMN) increases BubR1 abundance in vivo.

230 nicotinamide nucleoside of the nicotinamide mononucleotide (NMN) leaving group are oriented solely v

231 route, the amidation of NaMN to nicotinamide mononucleotide (NMN) occurs before the adenylylation rea

232 with NAD(+) precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), prot

233 g NAD(+) and its bio-precursor, nicotinamide mononucleotide (NMN), from tumor microenvironments, ther

234 AMPT) to increase production of nicotinamide mononucleotide (NMN), the predominant NAD(+) precursor i

235 by the Nampt enzymatic product nicotinamide mononucleotide (NMN), was not blocked by the Nampt enzym

236 were rescued by treatment with nicotinamide mononucleotide (NMN), which bypasses the block in NAD(+)

237 e, converting nicotinamide into nicotinamide mononucleotide (NMN).

238 nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN).

239 acterially expressed LOV domains bind flavin mononucleotide noncovalently and are photochemically act

240 ns studied on average than in the individual mononucleotides of G and C.

241 se the templated polymerization of activated mononucleotides of the opposite handedness.

242 was identified, which was mutated by either mononucleotide or dinucleotide adenosine deletions in 64

243 (millimolar) concentrations of nicotinamide mononucleotide or NAMN for efficient catalysis.

244 Treatment with nicotinamide mononucleotide or nicotinamide riboside increases total

245 Under a neutral evolution model, each mononucleotide or oligonucleotide should have a symmetri

246 affected residues involved in binding flavin mononucleotide or pyridoxal 5'-phosphate and many of the

247 formation of long nucleic acid polymers from mononucleotides or short oligonucleotides remains elusiv

248 We previously reported that 5'-mononucleotides organized within a multilamellar lipid m

249 peed the reversal of formaldehyde adducts of mononucleotides over standard buffers.

250 ategy using common dimethoxytrityl-protected mononucleotide phosphoramidites and a single orthogonall

251 phatic acids and utilize a prenylated flavin mononucleotide (prFMN) as cofactor, bound adjacent to a

252 newly identified cofactor, prenylated flavin mononucleotide (prFMN).

253 emplate-directed polymerization of activated mononucleotides proceeds readily in a homochiral system,

254 Flavins (riboflavin and flavin mononucleotide) recently have been shown to be excreted

255 arsH that encodes an NADPH-dependent flavin mononucleotide reductase.

256 Cre-dependent sparse cell labeling based on mononucleotide repeat frameshift (MORF) as a stochastic

257 frequent frameshift mutations in the coding mononucleotide repeat of TFAM in sporadic colorectal can

258 pe-specific transcription of an out-of-frame mononucleotide repeat that is placed between a translati

259 onal strand asymmetry in the distribution of mononucleotide repeat tracts in the reference human geno

260 he DNA damage response gene ATR (exon 10 A10 mononucleotide repeat) have been previously described in

261 ze sequence context-dependent mutagenesis at mononucleotide repeats (A-tracts and G-tracts) in human

262 reveals diverse-length polymorphisms in long mononucleotide repeats (microsatellites) in several sero

263 Mononucleotide repeats (MNRs) are abundant in eukaryotic

264 Mononucleotide repeats interrupt contig assembly with in

265 nstability, more marked at dinucleotide than mononucleotide repeats.

266 n, utilization of extracellular nicotinamide mononucleotide requires prior conversion to NmR mediated

267 tidine (C), guanosine (G), and thymidine (T) mononucleotides, respectively.

268 The NAD(+) precursor nicotinamide mononucleotide restored the cellular NAD(+)/NADH ratio a

269 th electron shuttle molecules such as flavin mononucleotide, resulting in the formation of high-molec

270 An artificial flavin mononucleotide riboswitch and a randomly generated RNA s

271 Using experimental data for flavin mononucleotide riboswitch as a guide, we show that effic

272 al ribosome entry site (IRES) and the flavin-mononucleotide riboswitch.

273 y replacing alternative diSSRs, by replacing mononucleotide-rich tracts and, in fewer cases, by expan

274 To address this issue, we removed all mononucleotide runs >3N from the yeast lys2DeltaBgl and

275 ne typically occur in simple repeats such as mononucleotide runs and are thought to reflect spontaneo

276 length threshold for polymerase slippage in mononucleotide runs is 4N.

277 transfer, render specific nucleotides along mononucleotide runs susceptible to base modification, wh

278 ding sequences and in short rather than long mononucleotides runs.

279 enterica serovar Typhimurium and the flavin mononucleotide-sensing ribB riboswitch from Escherichia

280 ifetime measurements of the intrinsic flavin mononucleotide show marked differences between "light" a

281 g complex I via interactions with the flavin mononucleotide site, proximal in the reaction pathway wi

282 city toward both nicotinate and nicotinamide mononucleotide substrates, which is consistent with its

283 ure of a complex with the product nicotinate mononucleotide suggests a mechanism for deamidation.

284 A range of commercially available 5'-mononucleotide supplemented infant formulas and three hu

285 Here, we report that a mononucleotide (T/U)16 tract located in the 3' untransla

286 ey interactions involving their bound flavin mononucleotide that suggest a unique catalytic behavior

287 ted an important role of adenine and guanine mononucleotides that bind to the regulatory Bateman doma

288 icotinamide, nicotinic acid, or nicotinamide mononucleotide, the Ca(2+) content of thapsigargin-sensi

289 on pathway by dephosphorylating nicotinamide mononucleotide to nicotinamide riboside.

290 It contains a flavin mononucleotide to oxidize NADH, and an unusually long se

291 It contains a flavin mononucleotide to oxidize NADH, and eight iron-sulfur cl

292 e responsible for catalyzing the addition of mononucleotides to a growing polymer using a DNA or RNA

293 We use a biological cofactor, flavin mononucleotide, to demonstrate the power of synchrotron

294 ynthetic mimic of the natural ligand, flavin mononucleotide, to repress riboswitch-mediated ribB gene

295 diffusivity between an oligonucleotide and a mononucleotide toward a negatively charged ITO electrode

296 active Cre recombinase transgene with a long mononucleotide tract altering the reading frame was stoc

297 llow for an unstable genetic feature, a long mononucleotide tract, in an essential gene.

298 dertaken for the preconcentration of five 5'-mononucleotides using the hollow fibers.

299 time for cotranscriptional binding of flavin mononucleotide, which decreases the concentration requir

300 Analogues of oligonucleotides and mononucleotides with hydrophobic and/or cationic phophot