ライフサイエンスコーパス: monooxygenase

1 ey enzyme in cholesterol synthesis, squalene monooxygenase.

2 etheneotrophs by inducing the enzyme alkene monooxygenase.

3 hich are currently misannotated as nitronate monooxygenase.

4 -3-methylglutaryl CoA reductase and squalene monooxygenase.

5 rsible ether lipid cleavage by alkylglycerol monooxygenase.

6 for the membrane-bound (particulate) methane monooxygenase.

7 l, and stores copper for particulate methane monooxygenase.

8 nase and peptidylglycine alpha-hydroxylating monooxygenase.

9 l for the soluble form of the enzyme methane monooxygenase.

10 inct from the previously described IsdG heme monooxygenase.

11 hydroxylation step is typically catalyzed by monooxygenases.

12 e biochemical repertoire of flavin-dependent monooxygenases.

13 DPH-dependent cytochrome P450 membrane-bound monooxygenases.

14 lycoside hydrolases and lytic polysaccharide monooxygenases.

15 ain pathway for PCET in the dinuclear copper monooxygenases.

16 cluded copper-dependent lytic polysaccharide monooxygenases.

17 hydroperoxide acting as oxidizing agents in monooxygenases.

18 ohydrate esterases, and lytic polysaccharide monooxygenases.

19 and NADPH, representative of class B flavin monooxygenases.

20 gnitude slower than rates reported for other monooxygenases.

21 gulated with particulate methane and ammonia monooxygenases.

22 conformational dynamics in flavin-dependent monooxygenases.

23 oding diterpenoid synthases, cytochrome P450 monooxygenases, 2-oxoglutarate-dependent dioxygenases an

24 We focused on the Flavin-containing monooxygenase-2 (Fmo-2) gene, a likely direct dsx target

25 otic detoxification enzyme flavin-containing monooxygenase-2 (FMO-2).

26 ds, we identify the enzyme flavin-containing monooxygenase 3 (Fmo3) to be a target of insulin.

27 Human flavin-containing monooxygenase 3 (hFMO3), a membrane-bound hepatic protei

28 We found that the single-component monooxygenase 3-hydroxybenzoate 6-hydroxylase (3HB6H) de

29 s applied anaerobically to the two-component monooxygenase 4-hydroxyphenylacetate 3-hydroxylase (HPAH

30 Starch-active polysaccharide monooxygenases (AA13 PMOs) oxidatively degrade starch an

31 cluster encoding an antibiotic biosynthesis monooxygenase (ABM) superfamily protein leads to a signi

32 factor beta1, suggesting that alkylglycerol monooxygenase activity affects IFN-gamma/lipopolysacchar

33 wo distinct [Cu-O-Cu](2+) sites with methane monooxygenase activity are identified in the zeolite Cu-

34 and reveal that alteration of alkylglycerol monooxygenase activity has a profound impact on the lipi

35 Alkylglycerol monooxygenase activity manipulation modulated the IFN-ga

36 trikingly, this response did not require the monooxygenase activity of PAM.

37 Here we found intracellular alkylglycerol monooxygenase activity to be an important regulator of a

38 Possibly as a result of reduced kynurenine 3-monooxygenase activity, elevated central nervous system

39 Although mutation of this residue abolishes monooxygenase activity, recent work has shown that mutat

40 Purified PA1024 did not exhibit nitronate monooxygenase activity; however, it displayed NADH:quino

41 p.Lys234Arg) mutations of the alkylglycerol monooxygenase (AGMO) gene were associated with KA relaps

42 ic oxide synthases (NOSs), and alkylglycerol monooxygenase (AGMO).

43 thrin, ribonucleotide reductase, and methane monooxygenase, all of which can bind NO and O2.

44 w that a single enzyme, the flavin-dependent monooxygenase AlpJ, can generate these metabolites from

45 6S rRNA gene amplicon sequencing and ammonia monooxygenase (amoA) abundance quantification through qu

46 We showcase ROCker using ammonia monooxygenase (amoA) and nitrous oxide reductase (nosZ)

47 lse addition of AgNPs on AOB and AOA ammonia monooxygenase (amoA) gene abundances and benthic nitrifi

48 ammonia and nitrite-oxidizing taxa (ammonia monooxygenase-amoA, nitrite oxidoreductase-nxrB, respect

49 Copper is a cofactor of the ammonia monooxygenase, an essential enzyme for the activity of a

50 FMO4, denoted as ancestral flavin-containing monooxygenase (AncFMO)1 and AncFMO4, respectively.

51 squito populations differed significantly in monooxygenase and beta-esterase activities, but not in V

52 otent and selective inhibitors of kynurenine monooxygenase and competitive for kynurenine.

53 e identifies RIFMO as a class A flavoprotein monooxygenase and is similar in fold and quaternary stru

54 olite data demonstrate that the kynurenine-3-monooxygenase and kynurenine aminotransferase branches o

55 ion activity and betaproteobacterial ammonia monooxygenase and nitrite oxidoreductase transcript abun

56 raction reactions catalyzed by dopamine beta-monooxygenase and peptidylglycine alpha-hydroxylating mo

57 repertoire of genes encoding cytochrome P450 monooxygenases and glutathione S-transferases associated

58 While CYP81Fs encoding cytochrome P450 monooxygenases and IGMTs encoding indole glucosinolate O

59 me ligation in chloroperoxidases or cyt P450 monooxygenases and peroxidases, respectively.

60 ation by substrate free lytic polysaccharide monooxygenases and provide insights that can be extended

61 dge of nature's repertoire of nonheme diiron monooxygenases and TIM-barrel-fold enzymes.

62 ssed genes (DEGs), including cytochrome P450 monooxygenases and UDP-glycosyltransferases, was shared

63 ygenase (peptidylglycine alpha-hydroxylating monooxygenase) and lyase (peptidyl-alpha-hydroxyglycine

64 Iron metabolism, monooxygenases, and secondary metabolism appeared to par

65 , a methyltransferase and a flavin-dependent monooxygenase are used iteratively to introduce C5 and C

66 ible implications of the results for toluene monooxygenases are considered as well.

67 TMTT The DMNT biosynthetic pathway and both monooxygenases are distinct from those previously charac

68 N-Hydroxylating monooxygenases are involved in the biosynthesis of iron-

69 Methane monooxygenases are nature's primary biological mechanism

70 droxylase (C4H; CYP73A) is a cytochrome P450 monooxygenase associated externally with the endoplasmic

71 Our findings have thus defined a novel monooxygenase-based oxygen sensing mechanism that has th

72 2,6-dichlorobenzoic acid (2,6-DCBA) and the monooxygenase BbdD transforming 2,6-DCBA into 2,6-dichlo

73 nzyme-fusion strategy to directly couple the monooxygenase (Bik2) and methyltransferase (Bik3) to eff

74 ther lipid species upstream of alkylglycerol monooxygenase but also other more complex lipids includi

75 ilarity with well characterized flavoprotein monooxygenases, but the protein has not been isolated an

76 rmore, we uncovered a unique Baeyer-Villiger monooxygenase (BVMO) VdtE that could transform the alkyl

77 ysis using flavin-containing Baeyer-Villiger monooxygenases (BVMOs) is a well-established tool to add

78 istinguished from other class A flavoprotein monooxygenases by its unique middle domain, which is inv

79 ts host gene, MICAL3 (microtubule-associated monooxygenase, calponin, and LIM domain containing 3gene

80 detoxification gene families, including P450 monooxygenases, carboxyl/cholinesterases, glutathione-S-

81 Squalene monooxygenase catalyses the oxidation of squalene to 2,3

82 The vast majority of flavin monooxygenases catalyze hydroxylation reactions on a sin

83 ene epoxidase (SQLE), also known as squalene monooxygenase, catalyzes the stereospecific conversion o

84 The family 2a CBMs of two monooxygenases,CfLPMO10 andTbLPMO10 fromCellulomonas fim

85 , we describe the characterization of a P450 monooxygenase CnsC from Penicillium that catalyzes the h

86 ng this process, the two-component carnitine monooxygenase (CntAB) catalyzes the oxygen-dependent cle

87 The ubiquitous flavin-dependent monooxygenases commonly catalyze oxygenation reactions b

88 enzyme adopts a fold common to FAD-dependent monooxygenases, contains a tightly bound FAD prosthetic

89 Kynurenine 3-monooxygenase converts kynurenine to 3-hydroxykynurenine

90 We show here that the FAD-dependent monooxygenase Coq6, which is known to hydroxylate positi

91 Cytochrome P450 monooxygenases CYP101A1 and MycG catalyze regio- and ste

92 first example of a wild-type cytochrome P450 monooxygenase (CYP116B46 from Tepidiphilus thermophilus)

93 er stromal expression of the cytochrome P450 monooxygenase CYP26 modulates BTZ sensitivity in the BM

94 Specifically, overexpression of the monooxygenase CYP2C8 or genetic ablation or inhibition o

95 by the Brassicaceae-specific cytochrome P450 monooxygenase CYP705A1 and is transiently induced in a j

96 substrate production by the cytochrome P450 monooxygenase CYP81F2 is localized to the surface of the

97 on of (E)-nerolidol into DMNT maps to a P450 monooxygenase, CYP92C5, which is capable of converting n

98 g TMTT accumulation corresponds to a similar monooxygenase, CYP92C6, which is specific for the conver

99 Additionally, a cytochrome P450 monooxygenase (CYP99A17), which genomically clustered wi

100 They are synthesized by cytochrome P450 monooxygenases (CYPs) and degraded by soluble epoxide hy

101 f the important enzyme class cytochrome P450 monooxygenases (CYPs), thereby influencing the detoxific

102 he initial identification of cytochrome P450 monooxygenases (CYPs/P450s), great progress has been mad

103 Cytochrome P450 monooxygenases (CYPs/P450s), heme thiolate proteins, are

104 ole hopping escape routes in cytochrome P450 monooxygenase, cytochrome c peroxidase, and benzylsuccin

105 lating monooxygenase (PHM) and dopamine beta-monooxygenase (DbetaM) are copper-dependent enzymes that

106 Kmo(-/-)) and characterized the kynurenine 3-monooxygenase-deficient mice using six behavioral assays

107 ique oxidative cleavage activity of the CTB3 monooxygenase domain in vitro.

108 tion and down-regulation of both 1,4-dioxane monooxygenase (dxmB) and aldehyde dehydrogenase (aldH) g

109 Squalene epoxidase (also known as squalene monooxygenase, EC 1.14.99.7) is a key rate-limiting enzy

110 ly a few bacteria can degrade it, using EDTA monooxygenase (EmoA) to initiate the degradation.

111 Nitronate monooxygenases encoded by NMO genes catalyse the oxidati

112 In soluble methane monooxygenase enzymes (sMMO), dioxygen (O(2)) is activat

113 ta-carotene hydroxylase and carotene epsilon-monooxygenase), enzymes associated with fruit flavor and

114 emonstrated for both ammonia lyases and P450 monooxygenases expressed within live bacterial colonies

115 parallel way by modulation of alkylglycerol monooxygenase expression and of tetrahydrobiopterin bios

116 n analysis, we pinpoint the loss of squalene monooxygenase expression as a cause of cholesterol auxot

117 ctor was highly correlated with flavonoid 3'-monooxygenase (F3'H) and a DFR in spathes, suggesting th

118 polyketide synthase (PKS), Flavin-dependent monooxygenase family 3 (FMO3) and glial cells missing (G

119 Members of the antibiotic biosynthesis monooxygenase family catalyze O2-dependent oxidations an

120 ging to the group-6 and 5 of soluble di-iron monooxygenase family, respectively.

121 one to phenalenone requires an FAD-dependent monooxygenase (FMO) PhnB, which catalyzes the C2 aromati

122 A flavin-containing monooxygenase (FMO) produced by A. sativum (AsFMO) was p

123 ygenase (Tmm), a bacterial flavin-containing monooxygenase (FMO), is found widespread in marine bacte

124 y be due in part to increased hepatic flavin monooxygenase (FMO)-mediated TMAO formation.

125 Flavin-containing monooxygenases (FMOs) are primarily studied as xenobioti

126 al circulation, and hepatic flavin-dependent monooxygenases (FMOs) efficiently oxidize TMA to TMAO.

127 mals rely on the oxidative flavin-containing monooxygenases (FMOs) to detoxify numerous and potential

128 (YUC) proteins constitute a family of flavin monooxygenases (FMOs), with an important role in auxin (

129 oxygenase from Xanthomonas campestris into a monooxygenase for oxidative cyclization of tryptophans.

130 nzymatic catalyst-based on a cytochrome P450 monooxygenase-for the highly enantioselective intermolec

131 soluble peptidylglycine alpha-hydroxylating monooxygenase from membrane-associated PAL.

132 rnative approach for these reactions, alkane monooxygenase from Pseudomonas putida (alkB) is able to

133 t exhibited by these enzymes in their native monooxygenase function.

134 transcript abundance of the archaeal ammonia monooxygenase gene (amoA) in nitrifying activated sludge

135 change in nitrification performance, ammonia monooxygenase gene abundances remained constant througho

136 Previous analyses of the ammonia monooxygenase gene amoA suggest that pH is an important

137 cteria and archaea (AOB/AOA) via the ammonia monooxygenase gene amoA, less is known about their small

138 rchaeota 16S rRNA genes and archaeal ammonia-monooxygenase gene copy number (qPCR) were significantly

139 P450-BM3 and mutants of this monooxygenase generated by directed evolution are excell

140 me deletions of one hydroxylase and two P450 monooxygenase genes resulted in the production of novel

141 t fsh is due to an E40K change in the flavin monooxygenase GS-OX5, a gene encoding a glucosinolate (G

142 lysis of the dechlorinating flavin-dependent monooxygenase, HadA, from the aerobic organism Ralstonia

143 Lytic polysaccharide monooxygenases have attracted vast attention owing to th

144 Furthermore, methanotrophs and methane monooxygenases have enormous potential in bioremediation

145 t monomeric NAD(P)H-dependent FAD-containing monooxygenase having a preference for NADPH.

146 cells lost their ability to degrade squalene monooxygenase in a cholesterol-dependent manner.

147 ole of tetrahydrobiopterin and alkylglycerol monooxygenase in ether lipid metabolism of murine macrop

148 dioxygenase, the previous name for nitronate monooxygenase in the GenBank(TM) and PDB databases, but

149 resistant mosquitoes, confirming the role of monooxygenases in pyrethroid resistance.

150 t negatively regulate cytochrome P450 (P450) monooxygenases in response to physiological and pathophy

151 results are consistent with AsFMO being an S-monooxygenase involved in allicin biosynthesis through d

152 Here, we report the structures of two Rieske monooxygenases involved in the biosynthesis of paralytic

153 dation of aromatic nuclei by cytochrome P450 monooxygenases is one of the major metabolic pathways of

154 n of substituted phenols by flavin-dependent monooxygenases is the first step of their biotransformat

155 PtmO5, a cytochrome P450 monooxygenase, is proposed to catalyze the formation of

156 smid-encoded soluble di-iron centre isoprene monooxygenase (IsoMO) is essential for isoprene metaboli

157 etabolism, including four-component isoprene monooxygenases (IsoMO), were identified and compared wit

158 ulatory enzymes in this pathway-kynurenine-3-monooxygenase (KMO) and tryptophan-2,3-dioxygenase (TDO)

159 mino transferase II (KATII) and kynurenine-3-monooxygenase (KMO) enzymes.

160 A number of inhibitors of kynurenine 3-monooxygenase (KMO) have previously been described as po

161 e enhanced by administering the kynurenine 3-monooxygenase (KMO) inhibitor, Ro 61-8048.

162 Kynurenine-3-monooxygenase (KMO) is a key FAD-dependent enzyme of try

163 Kynurenine 3-monooxygenase (KMO) is a therapeutically important targe

164 Inhibition of kynurenine 3-monooxygenase (KMO) protects against multiple organ dysf

165 Here we show that kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metaboli

166 : indoleamine dioxygenase (IDO1), kynurenine monooxygenase (KMO), and kynurenine aminotransferase II

167 usly identified member of YUCCA (YUC) flavin monooxygenase-like proteins (YUC8).

168 Lytic polysaccharide monooxygenase (LPMO) and copper binding protein CopC sha

169 rs in CopC proteins and lytic polysaccharide monooxygenase (LPMO) enzymes.

170 N-terminal family AA10 lytic polysaccharide monooxygenase (LPMO), a family 5 chitin-binding domain (

171 Bacterial lytic polysaccharide monooxygenases (LPMO10s) use redox chemistry to cleave g

172 Lytic polysaccharide monooxygenases (LPMOs) are a class of copper-containing

173 Lytic polysaccharide monooxygenases (LPMOs) are a recently discovered class o

174 Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes that

175 Copper-dependent lytic polysaccharide monooxygenases (LPMOs) are enzymes that oxidatively deco

176 Lytic polysaccharide monooxygenases (LPMOs) are industrially important copper

177 Lytic polysaccharide monooxygenases (LPMOs) are microbial enzymes secreted by

178 Lytic polysaccharide monooxygenases (LPMOs) are monocopper enzymes that catal

179 Lytic polysaccharide monooxygenases (LPMOs) are recently discovered enzymes t

180 Lytic polysaccharide monooxygenases (LPMOs) are redox-enzymes involved in bio

181 The recently discovered lytic polysaccharide monooxygenases (LPMOs) carry out oxidative cleavage of p

182 Lytic polysaccharide monooxygenases (LPMOs) catalyze oxidative cleavage of re

183 Lytic polysaccharide monooxygenases (LPMOs) catalyze the oxidative cleavage o

184 Copper-dependent lytic polysaccharide monooxygenases (LPMOs) contribute to the degradation of

185 Lytic polysaccharide monooxygenases (LPMOs) have a unique ability to activate

186 Lytic polysaccharide monooxygenases (LPMOs) have been proposed to react with

187 Lytic polysaccharide monooxygenases (LPMOs) offer tremendous promise for furt

188 fungi produce multiple lytic polysaccharide monooxygenases (LPMOs) with seemingly similar functions,

189 ng to the AA9 family of lytic polysaccharide monooxygenases (LPMOs).

190 nases, chitobiases, and lytic polysaccharide monooxygenases (LPMOs).

191 es by copper-containing lytic polysaccharide monooxygenases (LPMOs).

192 Nonheme diiron monooxygenases make up a rapidly growing family of oxyge

193 es is provided, with implications for copper monooxygenase mechanisms.

194 e, we identified a role for the flavoprotein monooxygenase MICAL3, an actin disassembly factor, in or

195 to selectively oxidize methane using methane monooxygenase (MMO) and methyl coenzyme M reductase (MCR

196 Methane monooxygenase (MMO) catalyses the O2-dependent conversio

197 o methanol under mild conditions are methane monooxygenases (MMOs) found in methanotrophic bacteria;

198 Methane monooxygenases (MMOs) mediate the facile conversion of m

199 ogy (CH) domain always follows an N-terminal monooxygenase (MO) domain.

200 l characterization of Nocardia farcinica Lys monooxygenase (NbtG), which has similar biochemical prop

201 f dithranol, a substrate for the nogalamycin monooxygenase (NMO) from Streptomyces nogalater As with

202 Nogalamycin monooxygenase (NMO) from Streptomyces nogalater is a cof

203 Bs3 is most closely related to plant flavin monooxygenases of the YUCCA (YUC) family, which catalyze

204 The cytochrome P450 monooxygenase P450 BM3 (BM3) is a biotechnologically imp

205 We report that a wild-type cytochrome P450 monooxygenase (P450(BM3) from Bacillus megaterium, CYP10

206 Cytochrome P450 monooxygenases (P450) in the honey bee, Apis mellifera,

207 Cytochrome P450 monooxygenases (P450s) are heme-thiolate proteins whose

208 Cytochrome P450 monooxygenases (P450s) are involved in metabolic resista

209 Cytochrome P450 monooxygenases (P450s) found in all domains of life are

210 than half (51.2%) of the CBP cytochrome P450 monooxygenases (P450s) that are up-regulated in the R st

211 Peptidylglycine alpha-amidating monooxygenase (PAM) (EC 1.14.17.3) catalyzes peptide ami

212 Peptidylglycine alpha-amidating monooxygenase (PAM) catalyzes a two-step reaction result

213 Peptidylglycine alpha-amidating monooxygenase (PAM) is an enzyme expressed by neuroendoc

214 ATPase, and peptidylglycine alpha-amidating monooxygenase (PAM), a copper-dependent membrane enzyme.

215 granules is peptidylglycine alpha-amidating monooxygenase (PAM), an enzyme essential for amidated pe

216 y identified peptidylglycine alpha-amidating monooxygenase (PAM), an enzyme required for generating a

217 ngle enzyme, peptidylglycine alpha-amidating monooxygenase (PAM), and lack of amidation renders most

218 ting enzyme, peptidylglycine alpha-amidating monooxygenase (PAM), and the presence of peptidergic sig

219 acids derived from the cytochrome P450 (CYP) monooxygenase pathway serve as vital second messengers t

220 ation, through the sequential actions of its monooxygenase (peptidylglycine alpha-hydroxylating monoo

221 ant reactivity, on the LPMO's polysaccharide monooxygenase/peroxygenase and reductant oxidase/peroxid

222 Cu(II)(O2(*-)) active species of the copper monooxygenase PHM and exhibits enhanced reactivity towar

223 Peptidylglycine alpha-hydroxylating monooxygenase (PHM) and dopamine beta-monooxygenase (Dbe

224 The flavin monooxygenase PhqK was found to catalyze spirocycle form

225 es, referred to as A and B, based on ammonia monooxygenase phylogeny.

226 Here, we report how the reactivity of a monooxygenase (PikC) from the pikromycin pathway is modi

227 Cytochrome P450 monooxygenases play a critical role in insecticide resis

228 Flavin-dependent monooxygenases play a variety of key physiological roles

229 methane C-H oxidation in particulate methane monooxygenase (pMMO) are currently unknown.

230 Particulate methane monooxygenase (pMMO) is one of the few enzymes that can

231 reaction is catalyzed by particulate methane monooxygenase (pMMO), a copper-dependent integral membra

232 xidation is catalyzed by particulate methane monooxygenase (pMMO), a copper-dependent, membrane metal

233 nzyme of these bacteria, particulate methane monooxygenase (pMMO), has been controversial owing to se

234 rimary metabolic enzyme, particulate methane monooxygenase (pMMO), is copper-dependent.

235 Using particulate methane monooxygenase (pMMO), we create a biocatalytic polymer m

236 monooxygenase (sMMO) and particulate methane monooxygenase (pMMO).

237 h as tyrosinase (Ty) and particulate methane monooxygenase (pMMO).

238 cell fusion: cwr-1 encodes a polysaccharide monooxygenase (PMO), a class of enzymes associated with

239 asing copy numbers of the functional methane monooxygenase pmoA gene.

240 ainst the highly-related particulate methane monooxygenase (pmoA).

241 Polysaccharide monooxygenases (PMOs), also known as lytic PMOs (LPMOs),

242 genes (encoding the alpha subunit of ammonia monooxygenases) preserved in a 5.8-m sediment core (span

243 initiated by two catabolic enzymes, propane monooxygenase (PRM) and tetrahydrofuran monooxygenase (T

244 n to be produced by cluster-independent P450 monooxygenases, probably to protect the fungus from the

245 ctural characterizations of a nonheme diiron monooxygenase, PtmU3, that installs a C-5 beta-hydroxyl

246 Differently from the ornithine monooxygenases PvdA, SidA, and KtzI, NbtG can use both N

247 In the classical O(2)-driven monooxygenase reaction, the reductant is needed in stoic

248 ochrome b561 associated with a dopamine beta-monooxygenase redox domain (CYBDOM), which localizes to

249 The monooxygenase responsible for co-metabolic transformatio

250 Rifampicin monooxygenase (RIFMO) catalyzes the N-hydroxylation of t

251 Flavin monooxygenase RslO9 then oxidatively rearranges the carb

252 Squalene monooxygenase (SM) is a rate-limiting enzyme in choleste

253 Squalene monooxygenase (SM) is an important control point in chol

254 Squalene monooxygenase (SM) is the second rate-limiting enzyme in

255 Squalene monooxygenase (SM), which synthesizes a cholesterol prec

256 nheme diiron enzymes such as soluble methane monooxygenase (sMMO) and fatty acid desaturases.

257 catalytic sites in two MMOs: soluble methane monooxygenase (sMMO) and particulate methane monooxygena

258 to the diiron active site of soluble methane monooxygenase (sMMO) and to a series of high-valent diir

259 Soluble methane monooxygenase (sMMO) carries out methane oxidation at 4

260 In nature, soluble methane monooxygenase (sMMO) is one representative example of no

261 ne in the catalytic cycle of soluble methane monooxygenase (sMMO).

262 lar interest, especially for soluble methane monooxygenase (sMMO).

263 The expression of squalene monooxygenase (SQLE) was associated with lethal cancer i

264 , including multicopper oxidases and ammonia monooxygenase subunit C (AmoC), and stress response gene

265 esentation of members of the luciferase-like monooxygenase superfamily points toward an important rol

266 Tyramine beta-monooxygenase (TbetaM) belongs to a family of physiologi

267 Cytochrome P450 monooxygenases (termed CYPs or P450s) are hemoproteins u

268 s to that of the methanotroph enzyme methane monooxygenase that activates methane at ambient conditio

269 echanism of a two-component flavin-dependent monooxygenase that can catalyze oxidative dechlorination

270 SidA is an N-monooxygenase that catalyzes the NADPH-dependent hydroxy

271 ver, knocking down shade (shd), encoding the monooxygenase that converts ecdysone (E) to the more act

272 etion of kmo-1, which encodes a kynurenine 3-monooxygenase that converts KYN to 3HKYN, drastically re

273 hitin was enhanced by a lytic polysaccharide monooxygenase that increases substrate accessibility by

274 Coq6 is thus a rare example of a flavin monooxygenase that is able to act on two different carbo

275 has been shown to encode a flavin-dependent monooxygenase that modifies tigecycline(1,2).

276 EmoA is an FMNH2 -dependent monooxygenase that requires an NADH:FMN oxidoreductase (

277 IsdGs are heme monooxygenases that break open the tetrapyrrole, releasi

278 Nitric oxide synthases (NOSs) are heme-based monooxygenases that convert l-Arg to l-citrulline and ni

279 f physiologically important dinuclear copper monooxygenases that function with a solvent-exposed acti

280 critical subunit of the particulate methane monooxygenase, the predominant methane oxidation catalys

281 na MG08 encodes a single particulate methane monooxygenase, the serine cycle for assimilation of carb

282 pane monooxygenase (PRM) and tetrahydrofuran monooxygenase (THM), belonging to the group-6 and 5 of s

283 TMA monooxygenase (Tmm), a bacterial flavin-containing monoo

284 can oxidize DMS to DMSO using trimethylamine monooxygenase (Tmm).

285 to using the iron-containing soluble methane monooxygenase to catalyse methane oxidation, with this s

286 elativorans sp. BNC1 can degrade EDTA with a monooxygenase to ethylenediaminediacetate (EDDA) and the

287 dopsis gene families such as cytochrome P450 monooxygenases to group the members functionally and sho

288 Toluene/o-xylene monooxygenase (ToMO) is a non-heme diiron protein that a

289 oxidation of n-alkanes including two alkane monooxygenases, two alcohol dehydrogenases, two aldehyde

290 Cytochrome P450 monooxygenases typically catalyze the insertion of one a

291 aving CCO, NOV2, previously reported to be a monooxygenase, using a purified enzyme sample revealed t

292 Alkylglycerol monooxygenase was expressed and active also in primary m

293 Cytochrome P450 monooxygenase was involved in the production of the two

294 data, a redox catalytic cycle for carnitine monooxygenase was proposed.

295 (SidA), a member of class B flavin-dependent monooxygenases, was selected as a model system to invest

296 nctional characterization of cytochrome P450 monooxygenases, we established that trans-sabin-3-ol but

297 ive-site component of the conserved isoprene monooxygenase, which are capable of retrieving isoA sequ

298 ivity of active sites in particulate methane monooxygenase, which are enzymes able to selectively oxi

299 h of these processes is catalyzed by methane monooxygenase, which converts methane or ammonia into me

300 n cytochrome P450 (P450) is a membrane-bound monooxygenase whose catalytic activities require two ele