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1 majority of responses from area 3a were non-monosynaptic.
2 amage also shaped the relative prevalence of monosynaptic A- versus C-fiber-mediated input to mature
3 ents, bypass local circuitry and have direct monosynaptic access to neurons projecting to brainstem a
6 ation induced unmasking and strengthening of monosynaptic Adelta drive to lamina I NK1R(+) neurons ma
7 ofold) and magnitude (by 75% in a subset) of monosynaptic Adelta-fiber but not monosynaptic C-fiber-e
9 s revealed that a proportion received silent monosynaptic Adelta-fiber input, suggesting that these m
10 sults of the present study indicate that the monosynaptic afferent input to mitral cells depends on t
12 virus in a transgenic Gpr151-Cre mouse line, monosynaptic afferents of habenular and thalamic Gpr151-
13 l activity by timing the neuronal firing via monosynaptic afferents, thalamic nuclei act as a relay s
14 rograde labeling in the amgBST compared with monosynaptic and 48-hour cases, whereas MEAad-injected c
15 nism that depends on the activity balance of monosynaptic and disynaptic pathways to inhibitory neuro
16 d and new M1 generated putative long-latency monosynaptic and non-monosynaptic effects; the majority
19 ns in three anesthetized monkeys revealed no monosynaptic and only one weak oligosynaptic EPSP after
20 ndicate that PPG neurons receive significant monosynaptic and polysynaptic input from brain regions i
21 cNTS PPG neurons in mice receive widespread monosynaptic and polysynaptic input from brain regions i
23 (R)-CPP, GluN2A/B antagonists, blocked both monosynaptic and polysynaptic NMDA EPSCs initiated by pr
25 tion of synaptic NMDA receptors expressed in monosynaptic and polysynaptic pathways from peripheral s
28 mulation of excitatory afferents evoked both monosynaptic and polysynaptic responses distributed in t
30 here were no significant differences between monosynaptic and PRV cases in the subnuclear distributio
31 in the central and medial extended amygdala, monosynaptic and transneuronal viral tracing experiments
32 n receptor, which allowed a demonstration of monosynaptic anterograde tracing from defined cells.
33 mined with network analysis tools applied to monosynaptic association (within one side) and commissur
34 ted that CFA inflammation reduced ADS in the monosynaptic C fiber input to lamina I neurokinin 1 rece
38 I (ECII)-->dentate gyrus-->CA3-->CA1 and the monosynaptic circuit ECIII-->CA1 have been considered th
41 opamine currents were separated into a fast, monosynaptic component and a slower-rising and decaying
42 that part of this locomotor drive involved a monosynaptic component coming directly from the lumbar l
43 ation (LTF) [6], which can be induced in the monosynaptic connection between Aplysia sensory and moto
44 gly, we uncovered a hitherto uncharacterized monosynaptic connection between cranial sensory neurons
45 onjugated cholera toxin subunit B, support a monosynaptic connection between these areas and poses th
46 ally assisted circuit mapping demonstrates a monosynaptic connection between these cholinergic neuron
48 - to fourfold higher than the probability of monosynaptic connections among corticocortical or cortic
50 -induced intramembrane proteolysis to reveal monosynaptic connections arising from genetically labele
51 significantly increased numbers of putative monosynaptic connections between PhMNs and these sprouti
52 d with two-photon microscopy to characterize monosynaptic connections between the Purkinje cells of j
53 ss-correlations in these preparations showed monosynaptic connections from 16/19 (84%) of EBSNs, but
54 le-cell patch recording was used to test for monosynaptic connections from hilar GPHNs to granule cel
57 found that corticoclaustral afferents formed monosynaptic connections onto both ClaC neurons and PV i
59 even cortico-motoneuronal cells, which make monosynaptic connections to alpha-motoneurons, can becom
60 om vibrissa sensory afferent fibers and send monosynaptic connections to facial nucleus motoneurons t
62 ticospinal tract in Old World primates makes monosynaptic connections to motoneurons; previous anatom
66 s in the primary motor cortex (M1) that make monosynaptic connections with motoneurons innervating sh
69 axon, which forms anatomical and functional monosynaptic connections with the A08a lateral dendrite.
70 s (up to 90), helped us to identify apparent monosynaptic connections, confirming the excitatory and
71 e lOFC sends requisite input to the BLA, via monosynaptic connections, to promote CS-induced cocaine-
72 dition to putative excitatory and inhibitory monosynaptic connections, we uncovered prominent millise
73 ory afferents and motoneurons typically form monosynaptic connections, while neurons innervating anta
78 s through two functionally distinct types of monosynaptic connections: (1) dendrodendritic synapses o
79 systematic biases in both their intralaminar monosynaptic connectivity and the post-synaptic partners
80 revealed short latency events indicative of monosynaptic connectivity between the inferior frontal g
81 in Sema3E and its receptor Plexin-D1 prevent monosynaptic connectivity in the cutaneous maximus muscl
82 the sensory response properties and upstream monosynaptic connectivity of cells mediating the CC or C
84 ncy (<20 ms) interneuron spiking, indicating monosynaptic connectivity, but firing probability progre
85 trains confirmed a fast and precisely timed monosynaptic connectivity, supporting the notion that SI
86 ary motor cortex ("new M1") and area 3a make monosynaptic cortico-motoneuronal connections with limb
87 ays afforded by the preceding elaboration of monosynaptic corticobulbar tracts, giving rise to enhanc
89 with weaker interneuron activity and reduced monosynaptic coupling between excitatory and inhibitory
90 count for this, we find that, in addition to monosynaptic coupling, PV-MSN interactions are mediated
94 e coronal slices containing V1, and recorded monosynaptic currents from excitatory and inhibitory neu
95 ation-specific interactions predicted by the monosynaptic distribution of horizontal connections.
97 d putative long-latency monosynaptic and non-monosynaptic effects; the majority of responses from are
98 he frequency of mEPSCs and the amplitudes of monosynaptic EPSCs evoked from the dorsal root and puff
99 ine significantly increased the amplitude of monosynaptic EPSCs evoked from the dorsal root and the f
100 nd long-lasting increase in the amplitude of monosynaptic EPSCs evoked from the dorsal root in approx
101 th oxotremorine-M decreased the amplitude of monosynaptic EPSCs in approximately 67% of neurons but i
102 /M4 double-KO mice, oxotremorine-M inhibited monosynaptic EPSCs in significantly fewer neurons ( appr
103 but increased the paired pulse ratio of the monosynaptic EPSCs in SNr GABA neurons, indicating a pre
104 rements exploiting the voltage dependence of monosynaptic EPSCs similarly indicated dominant expressi
106 t to prevent excessive depolarization by the monosynaptic EPSP and multiple action potential firings.
107 ve fields anywhere on the head evoked large, monosynaptic EPSPs ( approximately 5-20 mV) in tINs, at
109 ns from the pedunculopontine nucleus induced monosynaptic excitation in most recorded striatal cholin
110 nto CA3 pyramidal cells (PCs) provide strong monosynaptic excitation that exhibit prominent facilitat
111 al and electrosensory afferents elicit local monosynaptic excitation, quickly followed by inhibition
112 ifferentially influences the balance between monosynaptic excitatory and disynaptic inhibitory cortic
114 al retrosplenial cortex (RSC) and these form monosynaptic excitatory connections onto a wide spectrum
116 lls born before SE form functional recurrent monosynaptic excitatory connections with other granule c
117 nto BG output neurons sometimes precedes the monosynaptic excitatory drive from cortical afferents.
119 SNAP significantly reduced the amplitude of monosynaptic excitatory postsynaptic currents (EPSCs) ev
120 ts in small DRG neurons and the amplitude of monosynaptic excitatory postsynaptic currents of dorsal
121 ased HVACC currents in small DRG neurons and monosynaptic excitatory postsynaptic currents of spinal
122 tion of corticoclaustral afferents generated monosynaptic excitatory responses as well as disynaptic
123 ls of double-projecting vCA1 neurons induced monosynaptic excitatory responses in both the mPFC and b
125 nes in the principal olivary nucleus receive monosynaptic extra-somatic glutamatergic input from the
126 ysis, an approach that enables assessment of monosynaptic extracellular currents generated in differe
127 that layer 2/3 Pyr cells receive excitatory monosynaptic FF and FB inputs, which are opposed by disy
128 descending glutamatergic signal, most likely monosynaptic, from the MLR to the reticular formation th
129 e obtained from layer V pyramidal cells, and monosynaptic GABA(A) receptor-mediated IPSCs were elicit
130 n cells in specific layers and elicit robust monosynaptic GABAergic and nicotinic postsynaptic curren
131 ing activation of MS axons, we observed fast monosynaptic GABAergic IPSPs in the majority (>60%) of f
133 ulation of cholinergic interneurons triggers monosynaptic glutamate- and acetylcholine-mediated curre
134 parafascicular inputs evokes suprathreshold monosynaptic glutamatergic excitation in NGF interneuron
135 d that VTA-glutamate neurons receive a major monosynaptic glutamatergic input from the lateral hypoth
136 ation, to demonstrate that the activation of monosynaptic glutamatergic projections from anterior ins
138 ntifies a novel neural pathway through which monosynaptic glutamatergic ventral hippocampal field CA1
139 re, we found that the mPFC provides a direct monosynaptic, glutamatergic drive to both DRN 5-HT and G
140 tINs produce small ( approximately 2-6 mV), monosynaptic, glutamatergic EPSPs in the hindbrain retic
141 vation of BLA terminals in the vHPC provided monosynaptic, glutamatergic inputs to vHPC pyramidal neu
142 and pyramidal tract (PT) dendrites, whereas monosynaptic hippocampal input primarily targeted IT, bu
144 types of fusimotor drive that transform the monosynaptic Ia afferent feedback into task-dependent co
145 types of spinal interneurons (propriospinal, monosynaptic Ia-excitatory, reciprocal Ia-inhibitory, Re
148 entorhinal cortex (LEC) inputs, abGCs exert monosynaptic inhibition of mature granule cells (mGCs) t
151 om the auditory cortex and these form direct monosynaptic inhibitory connections onto lateral amygdal
152 collaterals; but reveal both excitatory and monosynaptic inhibitory currents in the ventral pallidum
153 thermore, continuous connections can undergo monosynaptic inhibitory LTP, independent of excitatory d
154 fference in the amplitude of stimulus-evoked monosynaptic inhibitory postsynaptic potentials (IPSPs)
155 ic SACs produced a GABA(A) receptor-mediated monosynaptic inhibitory response, followed by DA-D(1)-li
156 In contrast, tetanization elicited LTP of monosynaptic inhibitory responses in continuous, but not
158 ell (NAcSh) MSNs was fine-tuned by GABAergic monosynaptic innervation from adjacent fast-spiking inte
159 e vast majority of NTS LepR neurons received monosynaptic innervation from vagal afferent fibers and
160 d disynaptic pathways to inhibitory neurons: Monosynaptic input causes more powerful oscillations whe
161 stablish that inhibitory SG neurones receive monosynaptic input from a subset of unmyelinated primary
162 rons, which included a greater prevalence of monosynaptic input from low-threshold A-fibers when prec
163 emonstrate that mitral cells receive direct, monosynaptic input from olfactory receptor neurons.
164 , a ventral striatum structure that receives monosynaptic input from the olfactory bulb, is uniquely
165 n though some of these cells received potent monosynaptic input from the same LGNd neurons whose rate
166 hibits feeding when excited by touch-induced monosynaptic input from the second type of interneuron,
170 titative brain-wide map of neurons providing monosynaptic input to KNDy cells, as well as identify th
172 monstrated that NI GABAergic neurons receive monosynaptic inputs from brain areas processing importan
173 ubpopulation of BA neurons receives stronger monosynaptic inputs from context-responding vCA1 neurons
175 rd, we show that connections compatible with monosynaptic inputs from mechanosensory Rohon-Beard neur
176 rons in all layers of MEC receive convergent monosynaptic inputs from PrS and PaS and second, that el
180 s were explained by changes in the weight of monosynaptic inputs received by interneurons from new py
181 d a strategy to genetically target and trace monosynaptic inputs to a single neuron in vitro and in v
184 ieved to not project to CA2, send functional monosynaptic inputs to CA2 pyramidal cells through abund
185 tion, to characterize the firing patterns of monosynaptic inputs to dopamine neurons while mice perfo
186 Furthermore, we obtain brain-wide maps of monosynaptic inputs to MCH and OH cells, and demonstrate
187 ole-brain light-sheet imaging, we mapped the monosynaptic inputs to midbrain dopamine neurons project
188 e a powerful system for revealing the direct monosynaptic inputs to specific cell types in Cre-expres
189 cally targeted viral tracing to identify the monosynaptic inputs to the projection neurons of layer I
191 c insult that generates prominent excitatory monosynaptic inputs, both local recurrent and widespread
196 mined laminar distribution does not preclude monosynaptic interaction with neurons located in deeper
197 9% of sites), minimal focal shocks activated monosynaptic IPSCs at fixed latency (low jitter) that of
199 ation of GABAergic LH --> PVH fibers induced monosynaptic IPSCs in PVH neurons, and potently increase
201 nsmission, we evoked GABAA receptor-mediated monosynaptic IPSPs in deep cerebellar nuclei neurons by
202 rons in the LGN in a pattern consistent with monosynaptic labeling of koniocells, rather than disynap
204 57) occurred at latencies compatible with a monosynaptic linkage, including in motoneurons projectin
207 of oculomotor activation, comparable to the monosynaptic motor-evoked potential evoked by TMS of pri
208 es as likely mediated by either long-latency monosynaptic (n = 108) or non-monosynaptic linkages (n =
210 enetic activation of this projection elicits monosynaptic nicotinic and GABAergic currents in glomeru
211 N2B antagonist, caused modest suppression of monosynaptic NMDA EPSC amplitudes, but had a widely vari
213 Excitatory postsynaptic currents (EPSCs) in monosynaptic nTS neurons were recorded in the horizontal
217 e identified and characterized a nigro-vagal monosynaptic pathway in rats that controls gastric tone
220 Our results confirm the concept that the monosynaptic projection between HC and mPFC contributes
221 Here, we optogenetically silenced the direct monosynaptic projection from ventral/intermediate hippoc
224 we show that glutamatergic and, most likely, monosynaptic projections from the MLR activate stop cell
226 the whether any contribution is via direct, monosynaptic projections, or the direction of informatio
229 dent single-cell transcriptomic analyses and monosynaptic rabies tracing to compare mouse primary vis
230 veloped a complementary targeting system for monosynaptic rabies virus (RV) tracing that identifies d
232 ion segregation in these circuits, we used a monosynaptic rabies virus system to generate brain-wide
239 ults are therefore critical for interpreting monosynaptic rabies-based tracing in the sensory system.
240 crucial prerequisite of spoken language: (i) monosynaptic refinement of the projections of motor cort
243 IC and the lateral hypothalamus (LH) with a monosynaptic relay in the CeA and shed new light on the
245 lation of SuM(vgat/vglut2) terminals elicits monosynaptic release of both glutamate and GABA onto den
246 We found that commissural inputs evoked monosynaptic responses in both intratelencephalic (IT) a
247 ated a rapid and substantial decrease in the monosynaptic responses recorded at the first central sta
248 t connectivity of newborn Tau(VLW) DGCs, and monosynaptic retrograde rabies virus tracing showed that
249 ectroporation of DNA to target infection and monosynaptic retrograde spread of a genetically modifiab
251 he B-subunit of the cholera toxin which is a monosynaptic retrograde tracer was used as a control to
253 e developed a modified rabies virus-mediated monosynaptic retrograde tracing method to interrogate pr
255 ghput single-cell transcriptional profiling, monosynaptic retrograde tracing, and multiplexed FISH to
256 n to demonstrate cell-specific infection and monosynaptic retrograde transport of virus, which strong
257 analyses show diminished EPSP amplitudes in monosynaptic sensory-motor circuits in these mutants.
260 anisms underlying synapse formation in these monosynaptic sensory-motor connections are unknown.
261 o GTPase Cdc42 controls synapse formation in monosynaptic sensory-motor connections in presynaptic, b
263 d that firing of individual CHIs resulted in monosynaptic spontaneous inhibitory post-synaptic curren
265 -CTB neuronal transport was target specific, monosynaptic, stable for several weeks, and reproducible
266 and weak oscillations; in contrast, stronger monosynaptic stimulation (e.g., suppressive contextual s
267 el predicted characteristic contributions to monosynaptic stLFP signatures both for the regular-spiki
268 s finding suggests that twitches trigger the monosynaptic stretch reflex and, by doing so, contribute
270 m rs-fMRI in female mice with the underlying monosynaptic structural connectome as provided by the Al
271 bellum identified brainstem neurons that are monosynaptic targets of inhibition from the cerebellar f
272 rt and non-alert EEG states, we examined the monosynaptic TC responses and short-term synaptic dynami
273 no state-related changes in the amplitude of monosynaptic TC responses when TC spikes with similar pr
276 f the focal LFP signature of the single-axon monosynaptic thalamocortical connection as measured by s
277 than 1.2 ms were classified as definitively monosynaptic; these were seen only after stimulation wit
278 eling of contralateral LVST neurons within a monosynaptic time window all indicate an overwhelmingly
281 Glycoprotein-deleted rabies virus-mediated monosynaptic tracing has become a standard method for ne
283 vering DNA plasmids that allowed retrograde, monosynaptic tracing of each neuron's presynaptic inputs
285 Here, we use G-deleted rabies virus-mediated monosynaptic tracing to identify inputs to excitatory an
288 rus (RABV) has been the reagent of choice in monosynaptic tracing, since it permits the mapping of sy
292 ersectional labeling method and rabies viral monosynaptic tracing, which enables subtype-specific vis
293 efficient and prolonged photostimulation of monosynaptic transmission at the neuromuscular junction
295 ad short latency excitation, compatible with monosynaptic transmission over fast-conducting pathways,
296 o demonstrate a progressive delay of C fiber monosynaptic transmission to the spinal cord that is sim
297 , including both muscle stretch encoding and monosynaptic transmission, could be separated from other
300 reflexes (SRs) in ventral roots, presumably monosynaptic, were evoked by electrical stimulation of a