ライフサイエンスコーパス: morphogenesis

1 cial niche exhibit Notch activity during TMJ morphogenesis.

2 ll as subsequent cell fate specification and morphogenesis.

3 proper Wnt4 expression during root furcation morphogenesis.

4 s very critical to contribute to normal root morphogenesis.

5 ling pathway to CSF-cNs and rescue body axis morphogenesis.

6 of cell migration, tissue organization, and morphogenesis.

7 to microridges, and were required for their morphogenesis.

8 ne domains in dictating cell shape in tissue morphogenesis.

9 and in anatomical structure development and morphogenesis.

10 signaling effectors to regulate hippocampal morphogenesis.

11 ha5beta1 and Fn1 regulate aortic arch artery morphogenesis.

12 cise DEK1 subcellular localization during 3D morphogenesis.

13 division, centriole biogenesis, and neuronal morphogenesis.

14 ate the steps of tissue fate acquisition and morphogenesis.

15 neoformans stress response pathways and cell morphogenesis.

16 moesin (ERM) family control cell and tissue morphogenesis.

17 obo) receptors are required for proper islet morphogenesis.

18 enues for systematic decomposition of tissue morphogenesis.

19 ulation, is a well-studied example of tissue morphogenesis.

20 d importance of mechanical influences during morphogenesis.

21 tone acetylation in auxin signaling and root morphogenesis.

22 priate subcellular loci and orienting tissue morphogenesis.

23 apical extracellular matrix to promote wing morphogenesis.

24 ne involved in cell migration, adhesion, and morphogenesis.

25 in the beta-cells, is dispensable for islet morphogenesis.

26 ht the importance of competition in dendrite morphogenesis.

27 and N-hydrogels are constrained for vascular morphogenesis.

28 sculature disorganization and abnormal organ morphogenesis.

29 fgfr4 are required for vertebrate astrocyte morphogenesis.

30 tween cell biology and physics in regulating morphogenesis.

31 al role in controlling plant cell growth and morphogenesis.

32 display abnormalities in sensory compartment morphogenesis.

33 ncluding polysyndactyly and defects in skull morphogenesis.

34 study a possible role of Rme1 in C. albicans morphogenesis.

35 l division, neuronal development, and tissue morphogenesis.

36 n bundles and actin-bundle proteins in scale morphogenesis.

37 ppears to be critical at the onset of embryo morphogenesis.

38 ility to undergo distinct forms of branching morphogenesis.

39 f) that may be widely employed during tissue morphogenesis.

40 th, but can also control cell fate or tissue morphogenesis.

41 rs pancreatic bud fusion and pancreatic duct morphogenesis.

42 during mouse embryonic development and skin morphogenesis.

43 nd adverse events that amplify during tissue morphogenesis.

44 ed actin cytoskeletal dynamics in epithelial morphogenesis.

45 ive many biological events such as embryonic morphogenesis.

46 actions, and slowing turnover affects tissue morphogenesis.

47 that VEGF-C signaling is necessary for valve morphogenesis.

48 , touch, proprioception, osmoregulation, and morphogenesis.

49 of neural crest partially restores optic cup morphogenesis.

50 to our understanding of apical growth during morphogenesis.

51 of functions, including cytokinesis and cell morphogenesis.

52 scent tissues prevents cell mixing, powering morphogenesis.

53 the continuity of rim formation during disk morphogenesis.

54 ide insight into the molecular mechanisms of morphogenesis.

55 ar processes from proliferation and death to morphogenesis.

56 tes flotation through control of gas vesicle morphogenesis.

57 esource for the systematic analysis of ovary morphogenesis.

58 -breaking, germ layer specification and even morphogenesis.

59 uggest a role for these neurons in branching morphogenesis.

60 estigation of mechanisms underlying vascular morphogenesis.

61 of let-7 in HC differentiation and inner ear morphogenesis.

62 rization is fundamental for plant growth and morphogenesis.

63 g neighboring stereocilia during hair bundle morphogenesis.

64 network plasticity to accommodate growth and morphogenesis.

65 pressed genes (DEGs) related to blood vessel morphogenesis.

66 0 (PN0), just before the initiation of root morphogenesis.

67 llular matrix remodelling necessary for wing morphogenesis.

68 ognitive dysfunction, and abnormal dendritic morphogenesis.

69 the rearrangements that implement epithelial morphogenesis.

70 adhesion-based ECD regulation during animal morphogenesis.

71 ein determines right- or left-handed bristle morphogenesis.

72 h as cell proliferation, cell migration, and morphogenesis.

73 spects of cell fate specification and tissue morphogenesis.

74 n-plane stresses in shaping epithelia during morphogenesis.

75 implicated in septin organization [14], cell morphogenesis [15], and mitotic exit [16, 17], specifica

76 14], neurogenesis [12, 15-18], and embryonic morphogenesis [19].

77 res are sculpted by mechanical forces during morphogenesis(2).

78 sement membrane remodelling in global tissue morphogenesis(3-5).

79 itical for cell polarization and the ensuing morphogenesis(6,7).

80 ssion of the CAPZA2 variants affects bristle morphogenesis, a process that requires extensive actin p

81 ributions by CDK inherently link correct SPB morphogenesis, age and fate.

82 constitutes a major driving force for tissue morphogenesis, although the precise mechanism remains in

83 example of rosette-mediated postnatal tissue morphogenesis and a framework for studying the role of r

84 and stem cell biologists studying embryonic morphogenesis and adult tissue renewal.

85 ent progress in the field of mammalian tooth morphogenesis and also discuss the mechanisms regulating

86 for Prnd revealed impaired CNS blood vessel morphogenesis and associated endothelial cell sprouting

87 angiogenesis by showing uncoupling of vessel morphogenesis and blood-brain barrier formation.

88 c-di-GMP works as a major regulator of pole morphogenesis and cell development.

89 n the host and has a great influence on cell morphogenesis and cell division.

90 hat ANKS6 function is required for bile duct morphogenesis and cholangiocyte differentiation.

91 to newly identified molecules regulating ChC morphogenesis and connectivity as well as recent work li

92 des contribute in different ways to endotube morphogenesis and cooperate to cope with changing enviro

93 ent of basal progenitors during hair placode morphogenesis and diminished migration of melanoblasts.

94 stiffness as a key parameter that regulates morphogenesis and disease progression.

95 a-soft mouse oocytes, despite normal spindle morphogenesis and dynamics, inducing aneuploidy.

96 the only ERM in Drosophila, controls mitotic morphogenesis and epithelial integrity.

97 to be resolved, the cellular basis of islet morphogenesis and fate allocation remain unclear.

98 wth among different cell types drives tissue morphogenesis and function.

99 Overall, our study elaborates on how cristae morphogenesis and functional maturation are intricately

100 is an important property that underlies the morphogenesis and functions of epithelial tissues.

101 the chaperones negatively regulate neuronal morphogenesis and functions.

102 ibutes to the coordination of embryo growth, morphogenesis and gastrulation.

103 calization to centrosomes and impair spindle morphogenesis and genome stability.

104 d large-scale cellular rearrangements during morphogenesis and growth.

105 ploid sporophytes included genes involved in morphogenesis and halogen metabolism.

106 al and contemporary models of asymmetric gut morphogenesis and highlight key unanswered questions for

107 Gene perturbations disrupt morphogenesis and histo-differentiation.

108 t ion secretion is an important regulator of morphogenesis and homeostasis in epithelial acini.

109 To study the cellular biomechanics of acini morphogenesis and homeostasis, we used MDCK-2 cells.

110 n appropriate cell density for normal tissue morphogenesis and homeostasis.

111 ity, cell death is required for development, morphogenesis and homeostasis.

112 ons transmit mechanical forces during tissue morphogenesis and homeostasis.

113 signaling leads to altered endothelial cell morphogenesis and increased cell size, ectopic sprouting

114 with a transcriptional programme relating to morphogenesis and inflammatory processes.

115 The morphogenesis and maintenance of these stereociliary bun

116 Abnormal control of blood vessel morphogenesis and maturation is linked to the pathogenes

117 of a sigma factor of group ECF56, regulates morphogenesis and metal-ions homeostasis during developm

118 elaborate cytoskeletal structures to enable morphogenesis and motility, organize cell division, and

119 ization and its consequences for growth cone morphogenesis and motility.

120 understanding of the mechanisms controlling morphogenesis and neurogenesis in these structures has g

121 Anatomically, ductal morphogenesis and organ architecture are minimally pertu

122 s) undergo disassembly and reassembly during morphogenesis and pathological states.

123 to serve as an influential model of growth, morphogenesis and pattern formation.

124 involved in skeletal system development and morphogenesis and pattern specification.

125 , zebrafish Crb1 is not required for retinal morphogenesis and photoreceptor patterning.

126 However, the processes that control their morphogenesis and physiological expansion and contractio

127 de a structural framework for adrenal cortex morphogenesis and plasticity.

128 mical and mechanical-structural processes in morphogenesis and play an instructive role to a level th

129 In Arabidopsis, normal leaf morphogenesis and rate of leaf formation require m(6)A a

130 ave well established roles in cardiovascular morphogenesis and remodeling.

131 gulator functioning in CsYAB5-mediated organ morphogenesis and SA-mediated downy mildew resistance in

132 reted extracellular matrix (ECM) for rosette morphogenesis and show that the interaction of the ECM w

133 K in notochord vacuole biogenesis, notochord morphogenesis and spine development through mTORC1/TFEB

134 nt for endothelial TGF-beta signaling in OFT morphogenesis and suggest an important role for the endo

135 ression of three gene clusters: (i) neuronal morphogenesis and synaptic transmission genes in limbic/

136 the mesenchyme is known to guide epithelial morphogenesis and to help govern cell fate and eventual

137 here different cell types undergo concurrent morphogenesis and where averaging out of forces across c

138 link SCUBE3 to processes controlling growth, morphogenesis, and bone and teeth development through mo

139 ically responsive to contralateral variation morphogenesis, and Fibronectin-mediated inter-tissue adh

140 e decisions between esophageal and pulmonary morphogenesis, and its lack of expression results in EA/

141 on plays a pivotal role in cell development, morphogenesis, and other cellular functions.

142 d thereby contributes to establish body axis morphogenesis, and suggest it does so by controlling the

143 al primary cilia length and renal epithelial morphogenesis, and suggest that one aspect of diseases a

144 h, provide protection from stresses, mediate morphogenesis, and/or allow adaptation to different grow

145 meostasis that directly affects blood vessel morphogenesis, angiogenesis, and tissue permeability.

146 We show that in C. elegans morphogenesis, apical constriction in the retracting pha

147 ate functions of axon guidance and dendritic morphogenesis are accomplished by the same extracellular

148 The auxin signaling and root morphogenesis are harmoniously controlled by two counter

149 While basic mechanisms underlying morphogenesis are known in eukaryotes, it is often diffi

150 How pluripotency progression and morphogenesis are linked and whether intermediate plurip

151 molecules that coordinate dendrite and glial morphogenesis are mostly unknown.

152 ch tools, our conceptual models of branching morphogenesis are rapidly evolving, and the differences

153 direct skeletal system development and limb morphogenesis are transiently upregulated during blastem

154 iment with 74 grass species, conceptualising morphogenesis as the branching and growth of repeating m

155 which plays critical roles in developmental morphogenesis as well as synaptic physiology in adult li

156 entral hindgut is crucial for proper hindgut morphogenesis, as ectopic stabilization of beta-catenin

157 ling by the ECM regulates aortic arch artery morphogenesis at multiple steps: (1) accumulation of SHF

158 r dissect the genetic control of plant shoot morphogenesis at the cellular level.

159 iased screen for novel regulators of synapse morphogenesis at the larval neuromuscular junction (NMJ)

160 te zygotic genome transcription and onset of morphogenesis at the mid-blastula transition (MBT).

161 th a focus on the mechanisms that coordinate morphogenesis between the different epithelial cell type

162 r endothelial growth factor (VEGF) on thymic morphogenesis beyond its well-known role in angiogenesis

163 pathway that specifically controls dendritic morphogenesis but is dispensable for repulsive guidance

164 (OF), a transient gap that forms during eye morphogenesis by asymmetric, ventral invagination.

165 of the Z-ring is to govern nascent cell pole morphogenesis by directing the spatiotemporal distributi

166 indicate that cardiac function modulates OFT morphogenesis by triggering endocardial cell accumulatio

167 Epithelial fusion is a key process of morphogenesis by which tissue connectivity is establishe

168 gands that signal at short range to regulate morphogenesis, cell fate, and stem cell renewal.

169 eficiency shortens lifespan and affects wing morphogenesis, cell non-autonomously.

170 This question is central to morphogenesis, cell number control, and homeostasis.

171 vealed several misregulated genes related to morphogenesis, cellular excitability, and synapse format

172 ns in transcripts critical for outer segment morphogenesis, ciliogenesis, and synaptic transmission.

173 stasis analyses indicate that these dendrite morphogenesis defects result from a deficit in Cbln1/Glu

174 ation controls cell shape changes and tissue morphogenesis during animal development.

175 Their morphogenesis during development or pathology results fr

176 Rosettes are widely used in epithelial morphogenesis during embryonic development and organogen

177 rk controlling bile duct differentiation and morphogenesis during liver development.

178 over numerous known regulators of epithelial morphogenesis enriched in beta-catenin-stabilized adrena

179 r epithelial cell size dynamics (ECD)-during morphogenesis entail interplay between two opposing forc

180 of class-A genes in ovules for their proper morphogenesis, evoking the classic A-C antagonism of the

181 fate determination, trichome branching, leaf morphogenesis, floral transition, stress responses, frui

182 taset for uncovering conserved principles of morphogenesis for this clinically relevant bacterial sub

183 rovides the first visualization of astrocyte morphogenesis from stem cell to post-mitotic astrocyte i

184 al significance of WNT10A in regulating root morphogenesis has not been clarified.

185 However, the role of Slit ligands in islet morphogenesis has not yet been determined.

186 symmetry breaking, axiation, patterning, and morphogenesis have been extensively studied in developme

187 e is a mechanosensory pathway that regulates morphogenesis, homeostasis, and regeneration by controll

188 tion, which may explain their roles in plant morphogenesis, hormone signaling, cell fate determinatio

189 llular migration, differentiation and tissue morphogenesis; however, it has proved challenging to dir

190 rs can be repurposed upon injury to initiate morphogenesis; however, many differences exist between r

191 identify the dynamic morphoskeletons behind morphogenesis, i.e., the evolving centerpieces of multic

192 Tissues undergoing morphogenesis impose mechanical effects on one another.

193 Work identifying how stalk morphogenesis in a species of Alphaproteobacteria is con

194 aintenance of a straight body axis and spine morphogenesis in adult zebrafish.

195 ct, our method mimics two main strategies of morphogenesis in biomineralization, i.e., spatial and mo

196 NS-specific genes that regulate blood vessel morphogenesis in development and disease remain largely

197 broad implications for understanding apical morphogenesis in diverse epithelial systems.

198 the physical processes that underlie chiral morphogenesis in early development.

199 We observed delayed wood morphogenesis in eki compared with WT, along with a more

200 Cell polarity is fundamental for tissue morphogenesis in multicellular organisms.

201 Thus, ECD during morphogenesis in the heminotal epithelia of Drosophila p

202 we reveal reciprocal regulation of branching morphogenesis in the mammary gland, whereby stromal ACKR

203 the Reissner fiber, which controls body axis morphogenesis in the zebrafish embryo.

204 P expression exhibited accelerated dendritic morphogenesis, increased accumulation of postsynaptic ma

205 These findings separate microridge morphogenesis into distinct steps, expand our understand

206 t clustering of endocrine cells during islet morphogenesis is guided, at least in part, by repelling

207 Live imaging demonstrated that microridge morphogenesis is linked to apical constriction.

208 Manubrium morphogenesis is modulated by its connections with the g

209 However, early LR primordium (LRP) morphogenesis is not fully understood.

210 Morphogenesis is similarly affected by mutations in the

211 w extracellular matrix contributes to tissue morphogenesis is still an open question.

212 d in dynamic cell spaces to control cellular morphogenesis is unclear.

213 that PRCD is required for high fidelity disc morphogenesis, its precise role in this process remains

214 diated actin dynamics are required for early morphogenesis, its sustained activity is detrimental for

215 ing hiPSC-derived neurons enhanced dendritic morphogenesis, leading to larger neurons compared with t

216 Aberrant photoreceptor function or morphogenesis leads to blinding retinal degenerative dis

217 iling effects of RA deficiency in early lung morphogenesis, little is known about how RA regulates la

218 pment, intestinal epithelia undergo dramatic morphogenesis mediated by mesenchymal signaling to form

219 /intracellular, and subcellular ENS for cell morphogenesis, molecular imaging, cancer therapy, and ot

220 ubiquitin ligases essential for appropriate morphogenesis of cortical and hippocampal neurons and fi

221 mains at the plasma membrane (PM) during the morphogenesis of cotyledon pavement cells (PC) in Arabid

222 , the kinetics of which underpin the orderly morphogenesis of domain patterns on mesoscopic scales(1,

223 During morphogenesis of double-stranded DNA bacteriophages, a m

224 ts into biological mechanisms modulating the morphogenesis of endothelial networks and identify poten

225 Here, we investigated the morphogenesis of extraocular muscles (EOMs), an evolutio

226 The morphogenesis of fast growth depends on ecological conte

227 i, and opens new avenues for research on the morphogenesis of filamentous fungi.

228 s that lay the foundation for the subsequent morphogenesis of floral organs and success in reproducti

229 egies [17, 18], feeding methods [9, 19], and morphogenesis of frondose taxa together constrain their

230 describes the shape-shifting alterations in morphogenesis of human fungal pathogens and how they inf

231 (DEK1) is genetically at the nexus of the 3D morphogenesis of land plants.

232 tudy how protrusions form, we focused on the morphogenesis of microridges, elongated actin-based stru

233 intermediate filaments directly regulate the morphogenesis of microridges, elongated protrusions arra

234 c protein (BMP) pathway is essential for the morphogenesis of multiple organs in the digestive system

235 ix) interactions play essential roles in the morphogenesis of PAAs and their derivatives, the aortic

236 ify the biophysical processes underlying the morphogenesis of rosette colonies in the choanoflagellat

237 a critical role for Musashi proteins in the morphogenesis of terminally differentiated photoreceptor

238 quail embryo hearts during rapid growth and morphogenesis of the left ventricular wall.

239 hesion is required for bilaterally symmetric morphogenesis of the paraxial mesoderm.

240 Here, we addressed the role of lipids during morphogenesis of the rhabdomere, the microvilli-based ph

241 crystalline superstructure that directs the morphogenesis of the spicules.

242 f this protein phosphorylation module in the morphogenesis of the spore surface layers.

243 of their modern counterparts, namely in the morphogenesis of the ventral components of the rachis an

244 ynamically coordinates bilaterally symmetric morphogenesis of the vertebrate trunk but predisposes th

245 d with tumor aggressiveness, as well as with morphogenesis of tissues of neural crest-like origin (me

246 r correct function, and alterations in islet morphogenesis often result in diabetes mellitus.

247 ation in plants, such as phyllotaxis, flower morphogenesis, or lateral root initiation, have been ext

248 ll positioning and orientation during tissue morphogenesis, organ development and homeostasis.

249 rams during seed development, such as embryo morphogenesis, photosynthesis, and seed maturation.

250 te many processes in cell biology, including morphogenesis, physiology and responses to drugs and new

251 ntrol over both pluripotency progression and morphogenesis pivots from WNT to MEK signals.

252 Morphogenesis produces fast growth in different ways in

253 multiple and specific interactions with cell morphogenesis proteins that are linked to a dynamic cyto

254 regulating actin dynamics during epithelial morphogenesis, providing critical insights on the develo

255 Tissue morphogenesis relies on repeated use of dynamic behavior

256 However, the underlying changes in morphogenesis remain unknown.

257 contribution of these out-of-plane forces to morphogenesis remains challenging to evaluate because of

258 regulation of this process during epithelial morphogenesis remains unknown.

259 Quantitative analysis of plant and animal morphogenesis requires accurate segmentation of individu

260 Tissue morphogenesis requires dynamic intercellular contacts th

261 Second, spiracle morphogenesis requires the input of both trh and ct, whe

262 propose that robust patterning during tissue morphogenesis results from interplay between adhesion-ba

263 hree-dimensional (3D) model of mammary gland morphogenesis, sEV treatment induced hallmarks of malign

264 ith vasculature development and blood vessel morphogenesis signaling pathways were identified to be o

265 Yet, dental morphogenesis starts only after the corresponding endode

266 iary proteins involved in normal hair bundle morphogenesis, such as CDC42, RAC1, EPS8 and ESPNL.

267 Tension-based morphogenesis (TBM) is a conceptually simple and general

268 e important in tissue specification and limb morphogenesis, tendon cell biology and tenogenesis, grow

269 e significant association of a Gene Ontology morphogenesis term (including assigned roles for MSX1, M

270 the developmental genetics, cell biology and morphogenesis that underlie the incredible variation of

271 naling network, Foxf2 controls palatal shelf morphogenesis through regulating expression of multiple

272 has been proposed as a major contributor to morphogenesis throughout the nervous system [D.

273 iological and pathological processes such as morphogenesis, tissue homeostasis, wound healing, and tu

274 mechanisms of how plants program their leaf morphogenesis to adapt to environmental perturbations.

275 rated by these networks are harnessed during morphogenesis to drive various cell and tissue reshaping

276 cells often undergo dramatic changes during morphogenesis to form specialized structures, such as mi

277 derstanding how plant cells orchestrate root morphogenesis to gene expression with the STOP1-ALMT1 mo

278 ts and endothelial cells undergo coordinated morphogenesis to generate epithelial folds (secondary se

279 and patterning, but how it regulates tissue morphogenesis to reshape the wing into a haltere is stil

280 lapse imaging of c1vpda embryonic and larval morphogenesis to reveal a sequence of differentiation st

281 SOD5 was predominantly induced during hyphal morphogenesis, together with a fungal burst in reactive

282 Morphogenesis, tumor formation, and wound healing are re

283 gnaling as well as in the regulation of root morphogenesis under both normal and stress conditions.

284 Our formulation of tissue morphogenesis using time series opens new avenues for sy

285 th, survival, apoptosis, differentiation and morphogenesis via cytoskeletal remodelling and actomyosi

286 , and instead functions to control cartilage morphogenesis via regulation of the extracellular matrix

287 fate proteoglycan important in palatal shelf morphogenesis, was increased, whereas expression of coll

288 To address whether Neurog1 also controls morphogenesis, we analysed the migratory behaviour of ea

289 During morphogenesis, we found several unexpected alterations t

290 as its contribution to photoreceptor OS disc morphogenesis, we generated a Prcd-KO animal model using

291 Compared to floral morphogenesis, we understand little about the networks d

292 unique sensitized background to study ovule morphogenesis when C- and D-functions are simultaneously

293 riplakin was required to initiate microridge morphogenesis, whereas periplakin-keratin binding was re

294 development, synapse assembly, and hindbrain morphogenesis, which substantially extended our knowledg

295 nchyme, is required and sufficient for islet morphogenesis, while Slit1, which is predominantly expre

296 ignals and local regulators during internode morphogenesis will help elucidate the mechanisms coordin

297 rks are all important to harmonize internode morphogenesis with shoot development.

298 imply that IRX3/5 coordinate early limb bud morphogenesis with skeletal pattern formation.

299 t breakthroughs in the understanding of disc morphogenesis, with a focus on the molecular mechanisms

300 new insights into the mechanisms that drive morphogenesis, with special emphasis on polar septation,