ライフサイエンスコーパス: mortem

1 ormothermic conditions up to four hours post-mortem.

2 One case was diagnosed post-mortem.

3 a nigra (SN) from PD patients, analyzed post mortem.

4 m the pig bones and surrounding tissue, post-mortem.

5 half go completely unexplained despite post-mortem.

6 rformed in vivo by SPECT-CT imaging and post-mortem.

7 solution mapping of expression patterns post-mortem.

8 udden death medication-free individuals post mortem.

9 population level from extracted skulls post-mortem.

10 s of longissimus thoracis muscle at 2 h post-mortem.

11 half go completely unexplained despite post-mortem.

12 vivo (1050 um isotropic resolution) and post mortem (200 um isotropic resolution).

13 ficantly increased in synaptosomes from post-mortem AD brains compared to age-matched controls.

14 RNA-sequencing from post-mortem AD human brains shows downregulation in the expre

15 is upregulated on microglial cells from post-mortem AD patient brains, and high levels of CD33 inhibi

16 We report the presence of NK cells in post-mortem ALS motor cortex and spinal cord tissues, and the

17 ssay and in vitro autoradiography using post-mortem Alzheimer's disease brain tissue.

18 Gold standard post-mortem amyloid immunostaining was used for the determina

19 rd scores were associated with regional post-mortem amyloid load and neuronal neurofibrillary tangles

20 DCX-associated lissencephaly comes from post-mortem analyses of patient's brains, mainly since animal

21 ans, in part because of the reliance on post mortem analyses, which cannot be directly related to fun

22 rved and confirmed by more conventional post-mortem analysis; X-ray tomography and scanning electron

23 We outline the next steps for in vivo, post-mortem and clinical studies that can lay the groundwork

24 from tiles removed from the tokamak for post-mortem and controlled studies.

25 are significantly increased in HD human post-mortem and HD mouse striata, correlating with neuronal d

26 Post-mortem and identical location TEM analyses reveal that t

27 Post-mortem and in vivo studies implicate HSV-1 infection in

28 ferent psychiatric disorders, including post-mortem and in-vivo studies in humans and experimental st

29 Both post-mortem and neuroimaging studies have identified abnormal

30 Taken together, these post-mortem and preclinical findings identify TG2 as a critic

31 dation for understanding RNA regulation post-mortem and provide novel insights into RNA metabolism in

32 nt both at Day 14 in vivo and at Day 28 post-mortem) and marked and long-lasting sensorimotor deficit

33 tissues studies, where tissues obtained post-mortem are frequently used for research or therapeutic a

34 Taphonomic processes affecting bone post mortem are important in forensic, archaeological and pal

35 xperimentally produced faults, observed post-mortem, are sealed by fluid-bearing micro-pseudotachylyt

36 Some formed post-mortem around tusk-shells (Fissidentalium spp.), while o

37 g a validated consensus approach to the post-mortem assessment and scoring of cerebrovascular disease

38 validation of the criteria, by blinded post-mortem assessment of brain tissue from 113 individuals (

39 The post-mortem autoradiographic data showed that 18F-AV-1451 str

40 However, post-mortem blood has not been subjected to genetic analyses

41 In conclusion, post-mortem blood, which is usually disposed of during conven

42 ext to transcriptomic analysis of human post-mortem brain at single-cell resolution.

43 Post-mortem brain material from a subset of the multiple scle

44 ry and proteomics approach by comparing post-mortem brain material from schizophrenia patients and co

45 the immune system in a large sample of post-mortem brain of patients with schizophrenia: RNA sequenc

46 ese to a series of fibroblast lines and post-mortem brain samples from individuals with either adult-

47 er the past 25 years, studies analyzing post-mortem brain samples have found evidence of aberrant gly

48 Through analysis of the post-mortem brain samples in individuals with MDD that died b

49 e DNA methylation was quantified in 262 post-mortem brain samples, representing tissue from four brai

50 Neuropathological analysis of post-mortem brain tissue demonstrated that pIRE1alpha is expr

51 wn patterns of molecular convergence in post-mortem brain tissue from autistic subjects.

52 t aggregates, which are also present in post-mortem brain tissue from patients.

53 individuals with an antemortem MRI and post-mortem brain tissue from the Mayo Clinic Alzheimer's Dis

54 udinal retrospective study, we analysed post-mortem brain tissue of all individuals with an Alzheimer

55 nized intracellular inclusions in human post-mortem brain tissue of Lewy body disease cases, but not

56 We isolated microglia from post-mortem brain tissue of patients with MDD (n = 13-19) and

57 We also analysed matched CSF, post-mortem brain tissue, and iPSCs from the same participant

58 topography of parvalbumin expression in post-mortem brain tissue.

59 uorescent LMTK2 immunohistochemistry on post-mortem brain tissues and compared them to age-matched co

60 Using post-mortem brain transcriptomic data, we confirmed alteratio

61 ontrasts in different tissue types of a post mortem brain.

62 ine the tau PTM landscape present in AD post-mortem brain.

63 e-cell transcriptomic analyses of human post-mortem brains are important for documentation of patholo

64 r cortex, hippocampus and cerebellum of post-mortem brains from HD individuals, particularly in those

65 icroRNA (miRNA) expression profiling in post-mortem brains from individuals with ASD and controls and

66 Alcohol-dependent rats as well as post-mortem brains of human alcoholics and controls were anal

67 e PSEN1 allele expression is reduced in post-mortem brains of human EOfAD mutation carriers (and extr

68 The study of post-mortem brains of nonhuman primates (NHPs) has been limit

69 din, in 12 brain regions dissected from post-mortem brains of normal ageing (n = 10), pathological ag

70 rate SVs with RNA-sequencing from human post-mortem brains to quantify their dosage and regulatory ef

71 ired to form the aggregates observed in post-mortem brains.

72 irmed by pathological analysis of their post mortem brains.

73 stability of the sequestered molecules post-mortem but there is also potential for (palaeo)dietary r

74 that were analyzed for prion infection post-mortem by immunohistochemistry (IHC).

75 a luciferase-expressing UP strain, and post-mortem by qPCR and bacterial titration.

76 ife and had a diagnosis of AD confirmed post-mortem by standardized criteria.

77 Both PD and FTD/ALS are defined at post mortem by the presence of protein aggregates and the los

78 profile of cocaine dependence in human post-mortem caudate tissue.

79 stinguishing ante-mortem pathology from post-mortem change has been a major constraint in diagnosing

80 les are short and frequently mutated by post-mortem chemical modifications.

81 PSE was induced by incubation of post-mortem chicken carcasses at 37 degrees C for 200min.

82 h, but data on the role of nonselective post-mortem CIED (pacemaker or defibrillator) analysis in thi

83 were all cataloged in the Johns Hopkins Post-mortem CIED Registry.

84 softening was consistent, regardless of pre-mortem clinical findings including severity of IOP eleva

85 Post mortem, cochlear gain disappeared.

86 ain arterial wall thickening and poorer ante mortem cognitive performance and diagnosis of incident o

87 these questions, a study using a unique post-mortem cohort wherein whole body autopsy reports and bra

88 n of new Mycobacterium bovis infection (post-mortem confirmed) in at least one animal in a herd.

89 ow grade inflammation and non-arthritic post-mortem controls were analysed for the polyadenylation fa

90 ed for genes dysregulated in the autism post-mortem cortex (Odd Ratio (OR) = 1.11, P(corrected) 10(-1

91 ic, histologic and cellular profiles of post mortem COVID-19 (n = 34 tissues from 16 patients) and no

92 ion found an independent association of ante mortem CSF phosphorylated tau levels with postmortem cer

93 ar regression tested the association of ante mortem CSF tau levels with postmortem tau pathology adju

94 Implementation of post-mortem CT (PMCT), enhanced with targeted coronary angiog

95 Ante-mortem CWD tests of pre-clinical cervids may be an impor

96 d coverage achieved and the presence of post-mortem damage inflating sequencing errors.

97 osine to thymine mismatches, typical of post-mortem damage.

98 imilar to profiles obtained from mature post-mortem DaNs.

99 gnal and increased the concordance with post-mortem data sets.

100 y differ across hemispheres and support post-mortem data showing asynchrony in the loss of neuromelan

101 However, most analyses of post-mortem datasets are achieved by building new computation

102 rystals and provides the foundation for post-mortem deduction of the shape of the solid/liquid isothe

103 However, the irreversible post-mortem degradation(2) of ancient DNA has so far limited

104 highly sensitive and specific test for ante-mortem detection of infected animals would be of great v

105 asive, sensitive, and specific test for ante-mortem detection of infected animals.

106 iofluid or neuroimaging biomarkers, for ante-mortem detection of LATE.

107 ats, and results of the TMA analysis of post mortem diagenesis in bone are discussed, and implication

108 e extracts from healthy individuals and post mortem diagnosed AD patients, using a simple and fast pr

109 A definitive pre-mortem diagnosis of prion disease depends on brain biops

110 e identification of the variant enables ante-mortem diagnosis of similar cases and selective breeding

111 ghted features which should improve the ante-mortem diagnostic accuracy of multiple system atrophy.

112 tly, the CXCL10 GEA shows promise as an ante-mortem diagnostic tool for the detection of M. bovis-inf

113 al sites, during which surveillance and post-mortem diagnostics, including minimally invasive tissue

114 significance (P<0.05) in an independent post-mortem DLPFC data set (182 schizophrenia and 212 control

115 encing on neuronal nuclei isolated from post-mortem dlPFC of cocaine addicts and healthy controls.

116 ith DNA metabarcoding and assessment of post-mortem DNA damage allowed us to authenticate ancient DNA

117 DNA metabarcoding and the assessment of post-mortem DNA damage.

118 lates the entire molecular process from post-mortem DNA fragmentation and DNA damage to experimental

119 in a wide variety of tissue types from post-mortem donors.

120 Adipocere is a waxy substance formed post-mortem during incomplete anaerobic decomposition of soft

121 unds suggests that ambrein was produced post-mortem during the microbial decomposition of faecal resi

122 comparison with a grain map obtained by post-mortem electron backscatter diffraction (EBSD).

123 e occurs with the Janus separator where post mortem electron microscopy shows the PEC layer successfu

124 Post-mortem evaluations of healthy grafted tissue in such cas

125 neuropsychiatric diseases and there is post-mortem evidence of their deficit in FTLD.

126 Post-mortem examination and ultrasonographic studies (3 HERDA

127 0 turtles assessed by ultrasound and/or post-mortem examination developed GE, independent of season,

128 Post-mortem examination of an individual with a homozygous sp

129 Post mortem examination of Parkinson's disease brains suggest

130 Post-mortem examination of slaughtered reactors confirmed the

131 reactors to the skin test with positive post-mortem examination results (phenotype 1); ii) positive r

132 reactors to the skin test regardless of post-mortem examination results (phenotype 2) and iii) as in

133 eactors to the skin tests with positive post-mortem examination results (phenotype 3).

134 obacterial infection, and opportunistic post-mortem examination was performed on comparative intrader

135 curred in casualty, by medico-legal and post mortem examination, with no metabolic disorders.

136 ances and neurodegenerative features on post-mortem examination.

137 consent was requested from parents for post-mortem examinations (both complete diagnostic autopsy an

138 Post-mortem examinations were done on 14 people who died with

139 At 48h post-mortem, export quality loins were aged at -1.7 degrees C

140 on, but contrast with known patterns of post-mortem Fe mineralization.

141 dy, we demonstrate that myelin obtained post mortem from 8 out of 11 MS brain donors is bound by IgG

142 of implantable cardiac devices obtained post mortem from patients in wealthier nations have been unde

143 ometrial samples and ULF were collected post-mortem from sham-inseminated cows and from cows insemina

144 expression of small GTPase proteins in post-mortem frontal cortex tissues from AD patients with diff

145 ing trails, before being killed for the post mortem fungal growth.

146 By analyzing post-mortem gene expression data from the Allen Brain Atlas,

147 Leveraging a human brain atlas of post-mortem gene expression, we found that gliomas were local

148 clinical utility and combined yield of post-mortem genetic testing (molecular autopsy) in cases of S

149 Evidence from post-mortem, genetic, neuroimaging, and non-human animal rese

150 Here, through post-mortem genome-wide transcriptome analysis of the largest

151 ER stress markers was observed in human post-mortem glaucomatous TM tissues.

152 d HTT protein in peripheral tissues and post-mortem HD brain tissue, as well as in tissues from HD an

153 n of increased type I IFN signalling in post-mortem hippocampal brain sections from patients with SLE

154 constructed from ultra-high resolution, post-mortem hippocampal tissue was used to label seven hippoc

155 rden in small animals require laborious post-mortem histological analysis or resource-intensive, cont

156 he imaging analysis was corroborated by post-mortem histological analysis, which showed reversal of h

157 as in line with previous findings using post-mortem histology of the human substantia nigra and radio

158 an unsupervised clustering algorithm to post-mortem histopathological data from 895 patients with deg

159 predicted by the model closely tracked post-mortem histopathological findings.

160 els of active p38 MAPK were detected in post-mortem human ALS-FUS brain tissues.

161 rved across mammals and was detected in post mortem human amygdala, as well as human serum samples.

162 A sequencing from white matter areas of post-mortem human brain from patients with MS and from unaffe

163 ous studies have been carried out using post-mortem human brain or non-human cells.

164 xamined expression of synaptic genes in post-mortem human brain samples of these regions from eight p

165 E including AD and CTE with AD (CTE/AD) post-mortem human brain samples.

166 pecifically labeled pathological tau in post-mortem human brain tissue from Pick disease, progressive

167 temporal association of a dataset with post-mortem human brain.

168 affecting gene regulation in cells and post-mortem human brain.

169 assessed for their association with the post-mortem human brain.

170 al, parietal, and cerebellar regions of post-mortem human brains (n = 74) from non-cognitively impair

171 terized animal model of depression, and post-mortem human brains.

172 ional borders across species, including post-mortem human brains.

173 One post-mortem human brainstem was scanned at 11.7T to obtain st

174 ngle mouse cortical cells and to frozen post-mortem human cortical nuclei, matching the performance o

175 opsin-expressing ganglion cells in four post mortem human donor retinas.

176 -associated microgliosis in vivo and in post-mortem human samples.

177 Tau are increased by heroin use in the post-mortem human striatum, as well as in rats trained to sel

178 natomical investigations in animals and post-mortem humans have established that cerebro-cerebellar c

179 Post-mortem imaging and histology revealed traumatic microble

180 thies and may also have applications in ante-mortem imaging modalities.

181 sporter binding, an effect confirmed by port-mortem immunohistochemical analyses, suggesting that upr

182 raphy to identify epileptic animals and post-mortem immunohistochemistry to confirm blood-brain barri

183 toplasmic accumulations have been shown post-mortem in patients with Parkinson's disease and therefor

184 ing and reward function and are reduced post-mortem in schizophrenia.

185 listic approach involving complementary post-mortem, in situ, and operando analyses to elucidate full

186 We then identified GbbLCV-1 in post-mortem infant lung tissues demonstrating histopathologic

187 e poorest health (highest mortality and post-mortem inspection rejections, poorest walking ability, m

188 ound to be diagnostic in predicting the post mortem interval (PMI).

189 ince oviposition (i.e., egg laying) for post mortem interval determination, or for estimation of time

190 beta proteoforms did not correlate with post-mortem interval, suggesting they are not artefacts.

191 and cellular activity after a prolonged post-mortem interval.

192 from mouse and baboon over a series of post-mortem intervals.

193 Post-mortem interventions that restore brain perfusion should

194 The gold standard of post-mortem investigations should include both PMCT and invas

195 y of PMCTA as a first-line technique in post-mortem investigations.

196 We investigated the association between post-mortem iron levels with the clinical and pathological di

197 A new study examined post-mortem kidney tissue from 63 patients with COVID-19.

198 ing a combination of histological data, post mortem magnetic resonance imaging (MRI), and in vivo MRI

199 diet, pre-slaughter stress i) increased post-mortem malondialdehyde (MDA) formation except in vacuum-

200 pe receptors has been conducted only on post-mortem material, with no differences in methamphetamine

201 antifying neurogenesis in the caudal HF post-mortem may provide an objective, integrative measure of

202 nging interface reaction mechanisms via post mortem measurements.

203 035), but no other associations between post-mortem measures of tauopathy and intrinsic connectivity

204 A research autopsy is a post-mortem medical procedure performed on a deceased individ

205 1beta production was investigated using post-mortem midbrain tissues of humans at young (25-38 years)

206 Monte Carlo simulations estimated post-mortem migration of Anisakis from viscera to flesh incre

207 Post-mortem MRI was performed on non-fixed coronal hemispheri

208 and species-specific factors influence post-mortem mRNA stability are poorly understood.

209 nections between the redox imbalance in post-mortem muscle, early protein oxidation and the onset of

210 found a significant association between post-mortem neurodegeneration and in vivo volume loss in both

211 ional differences have been observed in post-mortem, neuroimaging and electrophysiological studies.

212 Comprehensive post-mortem neuropathological assessments were performed from

213 We performed a 15-year post-mortem neuropathological follow-up of patients in the fi

214 Pre-mortem, non-invasive magnetic resonance spectroscopy and

215 he primary motor cortices isolated from post-mortem normal control subjects, patients with familial A

216 examined genome-wide RNA expression in post-mortem nucleus accumbens from donors (N=26) with known l

217 fficult, as traditional methods rely on post-mortem or live-capture techniques.

218 (schizophrenia OR schizoaffective) AND (post-mortem OR postmortem) AND hippocampus.

219 Clinical blood and plasma samples and post mortem oral swabs submitted to the Liberian Institute fo

220 in experimental mice and also in human post-mortem pancreatic samples.

221 We found that USP13 is overexpressed in post-mortem Parkinson's disease (PD) brains.

222 Distinguishing ante-mortem pathology from post-mortem change has been a majo

223 ctional distribution of tau reported in post-mortem pathology studies, in that the most commonly affe

224 between in vivo18F-flortaucipir PET and post-mortem pathology.

225 Based on the analysis of post-mortem PD patients, Braak and colleagues suggested that

226 y, and executive functioning) to assess ante mortem performance.

227 nd that TG2 levels are increased in the post-mortem PFC of depressed suicide subjects relative to mat

228 s, we conducted a systematic search for post-mortem, pharmacological, functional magnetic resonance a

229 l blood anti-AN1792 antibody titres and post-mortem plaque scores (rho = - 0.664, P = 0.005).

230 Furthermore, post-mortem plasma cell-free DNA sequencing (liquid autopsy)

231 The post-mortem plasma cell-free DNA was successfully sequenced a

232 es of cell-free DNA were present in the post-mortem plasma of 12 autopsy cases.

233 Whole-exome sequencing of post-mortem plasma-derived cell-free DNA and eight frozen met

234 We confirmed this association with post-mortem quantification in 12 brains, demonstrating strong

235 lume loss using longitudinal MRI; (iii) post-mortem regional amyloid-beta protein and tau associated

236 ngle-subject level associations between post-mortem regional measures of neurodegeneration and tau in

237 e model of HIV-1 infection and in human post-mortem samples of HIV-1-infected brains.

238 ses revealed that liver, lung and heart post-mortem samples were marked by tissue abnormalities, such

239 utinely observed during the analysis of post-mortem samples, allows time-course monitoring of their c

240 patients with a positive antemortem or post-mortem SARS-CoV-2 result were considered eligible for en

241 We review post-mortem, serum-biomarker, CSF-biomarker, and neuroimaging

242 emonstrate S-acylation of SOD1 in human post-mortem spinal cord homogenates from ALS and non-ALS subj

243 ndividual transcripts show differential post-mortem stability, few studies have directly and comprehe

244 bulk electrochemical analyses, or other post-mortem strategies.

245 a growing convergence between hiPSC and post-mortem studies as both approaches expand to larger cohor

246 Despite ample evidence from post-mortem studies demonstrating exposure to both mild-repet

247 Post-mortem studies have determined that chronic active lesio

248 Post-mortem studies have not identified an association betwee

249 Post-mortem studies indicate that in ageing and Alzheimer's d

250 Evidence from murine models and human post-mortem studies indicates that monoaminergic nuclei under

251 sorder and new in vivo neuroimaging and post-mortem studies makes it timely to review this theory.

252 gnificantly up-regulated in three prior post mortem studies of schizophrenia.

253 respect to neurodegeneration after TBI, post-mortem studies on the long-term neuropathology after inj

254 We performed post-mortem studies on two patients with advanced Parkinson's

255 Recent post-mortem studies reported 22-37% of patients with multiple

256 Previous post-mortem studies reported conflicting findings regarding m

257 Recent genetic, molecular and post-mortem studies suggest impaired dopamine (DA)-D2 recepto

258 nt advances in psychiatric genomics and post-mortem studies that provide critical insights concerning

259 in accordance with previous animal and post-mortem studies, and consider the clinically asymmetric d

260 tion by bringing together findings from post-mortem studies, non-invasive imaging (including studies

261 A post mortem study confirmed that HDAC1 and HDAC2 paralogs are

262 luation of Advanced Cancer Environment) post-mortem study.

263 whole-to-dorsal fin (BH-DF) length from post-mortem subjects (R(2) = 0.99, n = 12).

264 Voxel-based morphometry, based on ante-mortem T1-weighted MRI, was used to identify cross-secti

265 orders did not reliably correspond with post-mortem tau pathology.

266 Through a combination of in vivo and post-mortem techniques, we aimed to characterize vascular bra

267 Post-mortem temporal cortex samples from Alzheimer's disease

268 ss the underlying etiology, we examined post mortem thoracic lymph nodes and spleens in acute SARS-Co

269 on method, with donor age </= 88 years, post-mortem time </= 63 h, overall preservation time </= 14 d

270 ical issue since it has been shown that post-mortem time delay and the method of fixation (i.e., perf

271 rfusion or immersion and with different post-mortem time delays (up to 5 hr) to mimic the way the hum

272 re mean aged 67.4 +/- 12.5 years with a post-mortem time of 20.7 +/- 14.7 h and ECD of 2641.0 +/- 362

273 donor tissue parameters included age), post-mortem time, overall preservation time, preservation tim

274 e loss of MALAT1 expression with longer post-mortem time, which potentially suggested a novel role of

275 source of variation in mRNA quality is post-mortem time.

276 urons to serially passaged sporadic ALS post-mortem tissue (spALS) extracts.

277 In human post-mortem tissue and mouse models humanized for apolipoprot

278 we examined mouse transgenic models and post-mortem tissue from human sporadic ALS cases.

279 18F-AV-1451 autoradiographic binding in post-mortem tissue from patients with Alzheimer's disease, pr

280 uced pluripotent stem cells, as well as post-mortem tissue from patients with FTLD-PGRN, we show that

281 ptor subunits have been observed in the post-mortem tissue of autistic individuals [8, 9], and GABAer

282 findings from in vivo-imaging and human post-mortem tissue studies in schizophrenic psychosis (SzP),

283 lored the composition of Lewy bodies in post-mortem tissue using electron microscopy and immunogold l

284 he PET images matched ligand binding in post-mortem tissue, and histological markers of dopaminergic

285 ed using cytochrome-oxidase staining of post-mortem tissue.

286 ence-based discussion of the quality of post-mortem tissues compared with other types of biospecimens

287 cted in the prefrontal cortex region of post-mortem tissues from human patients with Alzheimer's dise

288 brain slices and structural analysis of post-mortem tissues obtained from animals exposed to endothel

289 ties reported in RPE cells studied from post-mortem tissues of affected m.3243A > G mutation carriers

290 We also discuss the advantages of using post-mortem tissues over other types of biospecimens, includi

291 wide patterns of DNA methylation in 223 post-mortem tissues samples isolated from three brain regions

292 espiration, undergo profound changes in post mortem tissues.

293 ucoma, primary human TM cells and human post-mortem TM tissues, we show that increased ECM accumulati

294 rin (CERE120) gene therapy, the longest post-mortem trophic factor gene therapy cases reported to dat

295 s in vitro prion amplification assay as ante-mortem TSE test for live and asymptomatic small ruminant

296 NA seen in lumbar CSF translated to the post-mortem ventricular CSF.

297 ase neuropathological changes with 1638 ante-mortem volumetric head MRI scans spanning 1.0-16.8 years

298 in the brains of schizophrenic patients post mortem was observed compared to age-matched controls.

299 ar junction of 15 week-old C57BL/6 mice post mortem, we show the bone cortical porosity simultaneousl

300 l differentiation of protein aggregates post-mortem would be advantageous for the insight into the pr