ライフサイエンスコーパス: most notably

1 Most notably, 1 reacts with catechol borane to afford th

2 f 3 colonic catabolites of bacterial origin, most notably, 3-(3'-hydroxy-4'-methoxyphenyl)hydracrylic

3 Most notably, 38% of natal male PATS receiving gender-af

4 t photoproduction rates of nitrite and HONO (most notably, 4-nitrophenol and 2-methyl-4-nitrophenol)

5 istinct, previously undescribed forms of HA, most notably a 150 angstrom-long triple-helical coil of

6 es seen with broad spectrum HDAC inhibitors, most notably a block in the differentiation of rod photo

7 evealed some commonalities across organisms, most notably a consistent role of positive selection in

8 Elucidation of tumor biology principles, most notably a deeper understanding of the complexity of

9 and COS in the presence of metal catalysts, most notably a dinuclear aluminum complex.

10 ffects are observed in the infrared spectra, most notably a strong blue shift of the symmetric hydrog

11 Most notably, a GIT1-R283W variant reported in four inde

12 Most notably, a large proportion of proteins found in us

13 Most notably, a new Resistomes & Variants module provide

14 to several uncultured prokaryotic lineages; most notably, a SAR406 representative is attributed with

15 Most notably, a single serine-to-alanine substitution in

16 particular logistical challenges in Africa, most notably access to bioinformatics expertise and inte

17 Most notably, activation of the kinase involves previous

18 e mechanisms involved in energy expenditure, most notably adaptive thermogenesis.

19 ctin accumulation, TGF-beta expression, and, most notably, age-related impairments in mitochondrial b

20 Most notably, all plant HMGLs also contained a specific

21 as alignment accuracy, peak resolution, and most notably, allele-specific binding detection.

22 of facile oxidative bond-forming reactions, most notably allowing access to the first examples of Gr

23 fications in the methods for developing AUC, most notably, alterations in the nomenclature for approp

24 Most notably, although Prdm9(-/-) germ cells undergo cyt

25 ime in the effects of some of these factors, most notably an attenuation of the difference between pa

26 ecificity can lead to unwanted consequences, most notably an enhanced susceptibility to infection.

27 acked key RbcS RubisCO-binding determinants, most notably an extended N-terminal loop.

28 differences across multiple microbial taxa, most notably an increased relative abundance of the Bifi

29 e-metal and drug-eluting stent implantation, most notably an upregulation of aggrecan, a major ECM co

30 Most notably, an afternoon peak in cyanophage transcript

31 Most notably, an alternative RuBisCO-mediated CO(2) redu

32 is case, prominent effects on host proteins, most notably angiotensin-converting enzyme 2, might also

33 Most notably, application of ultrasound pulses of longer

34 n changes of glutamic acid residue E141 and, most notably, arginine R148 facilitate bidirectional pro

35 Used most notably as aids to psychotherapy for the treatment

36 razines, some furans and pyridines increased most notably at temperatures 50 degrees C.

37 arked differences between males and females, most notably at the CHRNA3 locus, and variants associate

38 n of several common mouse and human targets, most notably BCL9, predicted survival in HCC patients.

39 etween different cohorts or variant classes, most notably between the exome variant sets which sugges

40 vel therapies targeting certain aberrations, most notably BRCA1/2 mutations, mismatch repair (MMR) de

41 monomeric" spherical polymersomes, evidenced most notably by a step-growth-like relationship between

42 osystem function without affecting richness, most notably by affecting population densities and commu

43 f the unsaturated aldehyde via its C=O bond, most notably by electronic modification of the surface a

44 ic mechanisms to suppress tumor cell growth, most notably by enabling an effective antitumor immune r

45 t efforts have been focused on targeting it, most notably by inhibiting its AURKB kinase subunit.

46 these 'locally dead' domains by macrophages, most notably by microglia of the central nervous system.

47 y a variety of small transmembrane peptides, most notably by phospholamban in cardiac muscle and sarc

48 ctivators, phosphodiesterase inhibitors, and most notably by stimulation of G protein-coupled recepto

49 endent on apical secretion of chloride ions, most notably by the CFTR channel, which has been suggest

50 ctivity is associated with various diseases, most notably cancer, making this pathway an attractive t

51 biomarkers for a broad range of pathologies, most notably cancer.

52 es have occurred in several Candida species, most notably Candida glabrata and more recently Candida

53 development of genetically modified T cells, most notably CAR T-cell therapy.

54 associated with severe systemic anaphylaxis, most notably caused by Hymenoptera envenomation.

55 ty, excluding factors on the causal pathway (most notably, CD4 cell count, clinical signs of advanced

56 peractivation state in the memory T subsets, most notably CD8(+) T cells, while preserving the recove

57 Cell cycle regulators, most notably Cdkn2a, were upregulated by p53 inactivatio

58 the causative agents of many human cancers, most notably cervical cancer.

59 Most notably, changes in cortical oxy-haemoglobin during

60 le pairs of flies follow a distinct pattern, most notably characterized by an activity trough at dusk

61 Most notably, children and adults recognize that parents

62 ds utilize new and unexpected binding modes; most notably, compounds substituted with bulky hydrophob

63 mponents and functions of the immune system, most notably cytokine production and immune cell migrati

64 Most notably, decreased phosphorylation of alpha-tropomy

65 Most notably, despite the inability to induce detectable

66 city of cells is relevant to diverse fields, most notably developmental and stem cell biology, regene

67 Psychotherapies, most notably dialectical behavior therapy and psychodyna

68 Most notably, differential methylation analysis of chrom

69 mational changes throughout full-length tau, most notably diminishment of long-range interactions bet

70 ncordant with levels of DLL3 expression and, most notably, DLL3 immunoPET yielded rank-order correlat

71 to trigger aberrant inflammatory responses, most notably during inflammatory bowel diseases.

72 of algae biomass by heterotrophic bacteria, most notably during massive marine algae blooms.

73 fascinating and complex dynamical behavior, most notably dynamical heterogeneity (DH), a phenomenon

74 athogenesis of other eosinophilic disorders, most notably eosinophilic esophagitis.

75 ular sarcoma types, certain fusion partners, most notably EWSR1, are not tumor specific (and may, in

76 nclude intermittent bioenergetic challenges, most notably exercise and dietary energy restriction, ca

77 ations in JAK2 have been identified in MPNs, most notably exon 12 mutations in PV.

78 Most notably, F587L at the Palm and Thumb interface stab

79 netic and clinical-demographic risk factors (most notably familial aggregation and psoriasis sub-phen

80 e that solid-phase ligands in oxic sediment, most notably Fe oxides, may have a critical role in cont

81 hylation among atopic subjects was observed, most notably for cg21220721 and cg11699125 (ACOT7).

82 s of formation of certain reaction products, most notably for HCOO(-), C2H4, and C2H5OH over Cu(100)-

83 rom 2005 to 2013, USA100 incidence decreased most notably for hospital-onset (6.1 vs 0.9/100 000 pers

84 erapeutic efficacy in human clinical trials, most notably for those in patients with hemophilia B (re

85 o sustainable, synthetic hydrocarbons fuels, most notably for transportation purposes, continues to a

86 alpha-Linked GalNAc (alpha-GalNAc) is most notably found at the nonreducing terminus of the bl

87 key evolutionary transitions of Hymenoptera, most notably from phytophagy to parasitoidism and predat

88 one-responsive genes during stress response, most notably genes in the abscisic acid, jasmonic acid a

89 expression of 433 gene sets between groups, most notably genes related to intercellular proteins.

90 Most notably, genes for seed coat development such as su

91 However, the isotropic orientation of GBNs, most notably graphene oxide (GO), in previous experiment

92 ysis, Mongolian HCC exhibits unique drivers (most notably GTF2IRD2B, PNRC2, and SPTA1), the latter of

93 (PTM) associated with active transcription, most notably H3K27Ac and H3K36me2, whereas repressive H3

94 ntly higher rates of common adverse effects, most notably hand-foot skin reaction, diarrhea, and hype

95 uption of DNA binding of TRalpha and TRbeta, most notably heart rate, body temperature, blood glucose

96 Most notably, higher levels of beneficial gut bacteria c

97 Most notably, highly intransitive communities comprising

98 enotypes were also ameliorated by treatment, most notably hippocampal cell size and lifespan.

99 Most notably, homologation gives rise to analogues which

100 ructural peripheral nerve pathologies in NA, most notably hourglass-like constrictions.

101 Anal human papillomavirus (HPV) infection, most notably HPV16, the central cause of anal cancer, is

102 eripheral phenotypes were observed, however, most notably hypo-activity, exercise fatigue and bone ab

103 mpanied by elevated production of cytokines, most notably IL-6.

104 h levels both in the blood and in the lungs, most notably, IL-1RA, IL-6, IL-8, IP-10, and monocyte ch

105 rtners affecting several cellular processes, most notably immune regulation and DNA repair, but also

106 promising, several limitations still exist; most notably, improper structural organization of neural

107 Most notably in both patients and rats, all drilling too

108 ll regions and all future RCP scenarios, and most notably in Central America (CAM), Europe and Medite

109 erful method to study these complex systems, most notably in combination with molecular dynamics simu

110 peech sounds have largely been unsuccessful, most notably in extensive studies on great apes [5].

111 articularly at 7 days of differentiation and most notably in focal adhesion and PI3K-AKT signalling p

112 pes derived from a diverse range of tissues, most notably in glioma.

113 h higher nonlinear variation in north China, most notably in Heilongjiang Province, the major grain b

114 of dialysis - particularly haemodialysis and most notably in high-income countries (HICs) - the rate

115 als of mixed ancestry has many applications, most notably in identifying disease-susceptible loci tha

116 exophilin4 caused corresponding impairments, most notably in motor learning and coordination.

117 cine serotype invasive pneumococcal disease, most notably in older adults, since introducing a 13-val

118 one species had predicted plastid targeting, most notably in Panicum virgatum which had 1,458 protein

119 microtubule stabilization operates in vivo, most notably in plant cells where turgor-driven tensile

120 man cancer cell lines and cancers, including most notably in prostate and ovarian cancers.

121 tempts show that some high profile results---most notably in psychology, but in many other discipline

122 enes with divergent and opposing regulation, most notably in reproductive genes which are over-expres

123 d UC were restored by anti-cytokine therapy, most notably in responders.

124 plicated in a variety of cellular processes, most notably in response to changes in oxygen availabili

125 re found along many coasts around the world, most notably in south and southeast Asia but also in the

126 entified positions of mutational plasticity, most notably in surrounding linker regions.

127 ral amphid cilia are different between them, most notably in the absence of 'winged' cilia morphology

128 This patient had multiple joint deformities, most notably in the bilateral metacarpophalangeal joints

129 significant upregulation of gene expression, most notably in the cerebellum.

130 eposits have been confirmed in brain tissue, most notably in the dentate nuclei and globus pallidus.

131 r, bacteria themselves suffer from diseases, most notably in the form of viral pathogens termed bacte

132 lt stem cells in several epithelial tissues, most notably in the intestinal crypts, and is highly up-

133 hibitors significantly reduced tumor burden, most notably in the IRS-1-deficient group.

134 tream pathological effects in remote organs, most notably in the lungs.

135 It is most notably in the MF59 adjuvant, a component in some s

136 list-based kidney transplant rates differed, most notably in the Northeast and Midwest.

137 several unique challenges and opportunities, most notably in the perioperative setting.

138 ted the potential benefits of this approach, most notably in the SIV model, but safety concerns requi

139 um enolates in several classes of reactions, most notably in transformations forming tetrasubstituted

140 range of technical parameters was reported, most notably in tube current.

141 re noted in both sexes and across age groups-most notably in women and girls aged 16-24 years, in who

142 applications in cardiovascular biomedicine, most notably in: 1) the discovery of circulating protein

143 Most notably, in mammals pausing is positively correlate

144 Most notably, in mPFC, loneliness was associated with re

145 Most notably, in postnatal growing mice, the Gli1(+) cel

146 in synthesis at the three-dimensional level, most notably, in the environment of the ribosome functio

147 bute in diverse ways to protective immunity, most notably, in the provision of help for the productio

148 Vaccination has transformed public health, most notably including the eradication of smallpox.

149 ncreased synthesis of synaptic proteins, and most notably increased GluR1 and synaptic connectivity i

150 Most notably, individuals that were more responsive to t

151 Most notably, interneurons in the olfactory bulb, which

152 antial contributions to quantitative traits, most notably intracellular amino acid concentrations, gr

153 Most notably, it has trouble explaining why, in slot mac

154 Most notably, it provides the first method for reliable,

155 , supervised machine learning has drawbacks, most notably its dependence on a priori knowledge of exp

156 n by mutations in the hemopoietic stem cell, most notably JAK2(V617F), CALR, and MPL.

157 a couple of hotspots for positive epistasis, most notably L221/ R222 at which many combinations of mu

158 s transfer energy to the marine environment, most notably leading to catastrophic tsunamis.

159 areas were sensitive to both types of cues, most notably LO1, LO2 and V3B, making them additional ca

160 hierarchy of grouping organizations of FFR, most notably many participants sequentially recalled rel

161 Most notably, MarA activates expression of genes require

162 urse of this study, whereas some other taxa (most notably, massive Porites) were relatively unaffecte

163 s are associated with various interventions, most notably mechanical ventilation.

164 Most notably, Mendelian disease genes, particularly thos

165 economic factors in shaping health outcomes, most notably mental health decline.

166 ndothelial cells, and choroid plexus cells), most notably microglia and/or macrophages.

167 changes in climate and industrial pollution (most notably, mid-19th century increases in mercury poll

168 the modeling indicated that many parameters, most notably minor amounts of ADP generated during autop

169 mature microRNAs in a 340R-dependent manner, most notably miR-305-3p, which we attribute to stabiliza

170 Most notably, mitochondrial morphology inside the tissue

171 roles in spindle orientation across systems, most notably Mud/NuMA and cortical dynein, the precise m

172 reptile pathogens comprising several genera, most notably Nannizziopsis, Ophidiomyces, and Parananniz

173 These treatments - most notably natalizumab for multiple sclerosis - have l

174 l theory, computer science, statistics, and, most notably, neuroscience.

175 ant for tackling several types of addiction (most notably nicotine addiction) and other compulsive be

176 Most notably, nicotine exposure increased proliferation

177 athway and can drive formation of melanomas, most notably of rare melanomas that occur on volar and m

178 trophil paracrine chemoattractant signaling (most notably of the inflammatory mediator leukotriene B4

179 cts with proteins in addition to dentilisin, most notably, oligopeptide-binding proteins (OBPs) and t

180 Most notably, our analysis reveals the co-dependency of

181 are greater numbers of human infections, and most notably outbreaks linked to extreme weather events

182 nesis of several neurodegenerative diseases, most notably Parkinson disease.

183 al nervous system by acting on ion channels, most notably pentameric ligand-gated ion channels.

184 Most notably, periodic beating did not emerge until the

185 Most notably, photocatalysts with more noncoordinating c

186 Most notably, procurement areas changed through time.

187 Most notably, pronounced sagittal crests are negatively

188 on populations, communities, and ecosystems, most notably providing intermittent disturbances and nov

189 Most notably, Pt-DA and Pt-G4K(+)B hydrogels show select

190 We found differences in serum fatty acids, most notably PUFA, in CD that correlated both with clini

191 -related challenges, colorectal cancer (CRC) most notably; recent consensus recommendations for CRC s

192 myces cerevisiae have been recently defined, most notably regarding direct interaction between Hsf1 a

193 Most notably, regimes are distinguished by a gradient of

194 negative limbs of the core circadian clock, most notably REV-ERBalpha.

195 ents in early postentry stages of infection, most notably reverse transcription.

196 Odor responses in several neurons, most notably RIA, are altered in imprinted animals.

197 splicing regulators were greatly increased, most notably, rpl10a When the levels of NMD-susceptible

198 ion observed for all steps of the mechanism, most notably Schiff base formation and hydrolysis.

199 esent across a range of different disorders, most notably schizophrenia but also anxiety and mood dis

200 ltiple tumors in the central nervous system, most notably schwannomas, and meningiomas.

201 of Ubqln2 on diverse physiological pathways, most notably serotonergic signaling.

202 . influenzae strains has also been observed, most notably serotype a.

203 Human coronaviruses, most notably severe acute respiratory syndrome (SARS)-Co

204 As) were readily degraded, other structures, most notably short-chain PFSAs and fluorotelomer sulfoni

205 is, they have more chronic comorbidities and most notably similar short-term and long-term mortality.

206 ns deletions of tumour suppressor gene loci, most notably SMAD4, which is homozygously deleted in nea

207 Several lifestyle factors, most notably smoking and alcohol, are associated with SP

208 Vertebrate SoxE paralogues, most notably Sox9/10, are essential for NC induction, de

209 Most notably, SS-31 modulated the surface electrostatics

210 Most notably, stereoselective copolymerizations of rac-8

211 Some microbial species (most notably Streptococcus anginosus) seem to characteri

212 exes involved in adaptation to perturbation, most notably, stress granule (SG) proteins, which respon

213 Most notably, substituting aspartate with glutamate (RGE

214 antages over hybridization-based approaches, most notably superior sensitivity and the capacity for d

215 licated in the pathogenesis of autoimmunity, most notably systemic lupus erythematosus (SLE), diabete

216 with potentially debilitating side-effects, most notably tardive syndromes and parkinsonism, as well

217 Drug Administration, with additional agents, most notably targeting tau, currently under clinical inv

218 Most notably, telomeres have a broad impact on pluripote

219 a handful of recurrent non-coding mutations, most notably TERT promoter mutations, have been reported

220 after correction for confounding variables, most notably testing rates, there was no association bet

221 nsion shows strong lineage-specific aspects, most notably that hypomethylated intervals around transc

222 identified a number of points of agreement, most notably that the overall dietary patterns in which

223 typical BCG measurement shows several waves, most notably the "I", "J", and "K" waves.

224 hagic E. coli (EHEC) owing to shared traits, most notably the ability to form A/E lesions.

225 to the unique features of the hydride anion, most notably the absence of valence p orbitals.

226 teria involved in many regulatory decisions, most notably the adaptation to cell envelope stress.

227 ic radiation force impulse (ARFI) technology-most notably the addition of a quality assessment of the

228 cleavage of several transmembrane proteins, most notably the amyloid precursor protein that results

229 However, a number of insect lineages, most notably the ants, have receptor gene repertoires ma

230 acquisition of mature brain vascular traits, most notably the blood-brain barrier.

231 Household surveys, most notably the Demographic and Health Survey (DHS), ru

232 l patterns of B. pseudomallei dissemination, most notably the dynamic nature of movement of B. pseudo

233 The DILT1D trial results, most notably the early altered trafficking and desensiti

234 Estimates were sensitive to inputs, most notably the effects of losing insurance on mortalit

235 Sb5 exudates, most notably the fractions larger than 3 kDa, promoted p

236 Our data indicate that some marine bacteria, most notably the highly abundant Pelagibacter ubique and

237 RKKY interaction found in fermionic systems; most notably the lack of a Fermi surface and absence of

238 or the structure-activity relationship data, most notably the lack of enantiospecificity and the tole

239 but display important differences, including most notably the lack of TMBS2 and the presence of a C-t

240 otentially important biophysical parameters, most notably the mechanical stability of the receptor-li

241 rganic frameworks offer numerous advantages, most notably the nearly infinite chemical space through

242 trongly determined by anthropogenic effects, most notably the number of species introduced (i.e., "co

243 to interior basins during past warm periods, most notably the Pliocene epoch, causing several metres

244 or spectroscopy of nanomaterial dispersions; most notably the possibility of observing solvent photol

245 ed aspects currently hamper its performance, most notably the quite frequent inability to obtain full

246 gions associated with other clinical events, most notably the regions harboring CKMT2 gene (creatine

247 ling, which are observed in several systems, most notably the regulated uncoupling of oxidative phosp

248 show dramatic changes in kinetic properties, most notably the slowing of the apparent ATP hydrolysis

249 e transcription of a set of genes, including most notably the stem cell factor SOX9, that promote pro

250 cover surprising features of STAT5 behavior, most notably the wholesale redistribution that occurs wh

251 Most notably, the attractive idea of replacing the all-t

252 n into distinct genotypes and lineages, and, most notably, the convergent evolution observed in recen

253 mic plant ash glasses from Mesopotamia, and, most notably, the development of a new type of glassmaki

254 Perhaps most notably, the device manufacturing is significantly

255 Most notably, the electrophilic character at the 4-posit

256 Most notably, the fatty acyl chain-dependent differentia

257 Most notably, the FOURIER (Further Cardiovascular Outcom

258 Most notably, the fusA1 mutant displayed greatly increas

259 Most notably, the genomic distance effect, whereby conta

260 Most notably, the geographic origin of honey bees is unc

261 Most notably, the increase of the acceptor strength led

262 g and interpreting nutrient or energy levels-most notably, the insulin/insulin-like growth factor 1 (

263 Most notably, the model built by the algorithm enabled o

264 Most notably, the onset of these phenotypes occurs at an

265 Most notably, the original ED2 produced unrealistically

266 t varies with the changes in the environment-most notably, the pH of the surrounding solution.

267 Most notably, the pipeline predicts TKR with AUC 0.943 +

268 Most notably, the relative abundance of Fusobacterium in

269 How their structural composition, most notably their quantitative morphology underlie thei

270 Most notably, there is an order of magnitude more hetero

271 Most notably, there was a substantial reduction in predo

272 Most notably, they are significantly more stable when ex

273 Most notably, this approach can also be applied to the a

274 Most notably, this difference allows listeners of adject

275 Most notably, this report demonstrates the generality of

276 s and suppression of many adipocyte programs most notably those associated with mitochondria.

277 osis-autophagy genes are mutated in cancers, most notably those enriched in microsatellite instable-h

278 eurotransmitter and neuromodulator circuits, most notably those involving cholinergic transmission, a

279 was reflected in the gene expression levels (most notably those of NDL1, CHALCONE SYNTHASE, and MYB D

280 iew summarizes some geologic considerations, most notably those related to geochemistry, that challen

281 ontributions to our understanding of vision, most notably through the study of eye movements, the dev

282 ity and marked successes have been achieved, most notably through the use of checkpoint blockade anti

283 Most notably, transplanted microglia exhibit robust tran

284 alized subpopulations of stromal cells, and, most notably, two distinct populations of clear cells.

285 ure and in vivo by lipidome-wide remodeling, most notably upregulation of saturated lipids and choles

286 regulation of M30 in epilepsy toward health, most notably valproic acid, whose effect on M30 expressi

287 xperimental literature on games of conflict, most notably variations on "matching pennies" games.

288 Encouragingly, some reefs-most notably Vietnam, Japan, Taiwan, New Caledonia and t

289 onstrated that some of these thinking tools, most notably visual thinking skills, can be taught throu

290 Most notably we observed that the enzyme can perform oxi

291 Most notably, we discovered that ectopic expression of t

292 Most notably, we identify robust RAMP interaction with a

293 uaternary carbons hinders their preparation, most notably when stereocontrol is required.

294 Most notably, when colonized by the DeltassrA strain, th

295 ift variant in exon 7 of NAA10, who presents most notably with microphthalmia, which confirms a prior

296 ts in a venous thrombotic phenotype in mice, most notably with vessel occlusion in large veins of the

297 th a lack of proanthocyanidins in seeds and, most notably, with an extreme reduction in fruit acidity

298 l growth, increased bacterial production and most notably, with substantial shifts in enzymatic activ

299 egate, reveals strong transmission patterns, most notably within households and between spouses.

300 Most notably, xenogeneic silencing proteins bind incomin