ライフサイエンスコーパス: mother cell

1 ing anaphase and the SPB that remains in the mother cell.

2 ir length roughly equals the diameter of the mother cell.

3 which actin cables emerge and grow into the mother cell.

4 nd thereby promotes their confinement in the mother cell.

5 ion in the cell lineage leading to the guard-mother cell.

6 ly slightly thinned as it curves towards the mother cell.

7 is engulfed by the membrane of the adjacent mother cell.

8 depends on the initial size of the committed mother cell.

9 dissection of daughter cells from the larger mother cell.

10 yielding the smaller prespore and the larger mother cell.

11 ion of the growth and DNA replication of the mother cell.

12 gth correlates with chromosome number in the mother cell.

13 f two spores (twins) forming within the same mother cell.

14 cells are formed within the cytoplasm of the mother cell.

15 owed by activation of sigma(E) in the larger mother cell.

16 block the DNA replication and growth of the mother cell.

17 gely absent from the SPB that remains in the mother cell.

18 properties before they are released from the mother cell.

19 which separate it from the cytoplasm of the mother cell.

20 A circles, which act as aging factors in the mother cell.

21 uires expression of the spoIIIA locus in the mother cell.

22 l transduction between the forespore and the mother cell.

23 mal layer differentiating into the megaspore mother cell.

24 ges de novo from a morphologically invariant mother cell.

25 , including protein aggregates, to the aging mother cell.

26 rotein aggregates and their retention in the mother cell.

27 cell wall degradation protein complex in the mother cell.

28 nstituents and prolonged the lifespan of the mother cell.

29 ansmits the longevity benefit of CR to moved mother cells.

30 ructures that had a strong bias to remain in mother cells.

31 on of INPs into terminally dividing ganglion mother cells.

32 which is highly up-regulated in their pollen mother cells.

33 with the Olig2(+) cells behaving as ganglion mother cells.

34 directed gene expression was enhanced in the mother cells.

35 stributed unequally between the daughter and mother cells.

36 is physically distinct from mitochondria in mother cells.

37 undergo continuous movement from buds toward mother cells [1].

38 septum that separates the forespore from the mother cell, a process that depends on the autolysin Spo

39 bias' (preferential plasmid retention in the mother cell) according to binomial distribution, thus li

40 although vacuolar acidity is reduced in aged mother cells, acidic vacuoles are regenerated in newborn

41 al scaling causes Start in both daughter and mother cells across growth conditions.

42 t were both long-lived and retained in aging mother cells after approximately 18 cells divisions.

43 Replicative aging in yeast is asymmetric-mother cells age but their daughter cells are rejuvenate

44 tivation (ETI), yeast cells have accelerated mother cell aging and mildly perturbed cell cycles.

45 The acceleration of ETI mother cell aging was not explained by increased reactiv

46 altered cell-cycle dynamics, and accelerated mother cell aging.

47 evidence that asymmetric distribution drives mother cell aging.

48 Despite the gradual aging of the mother cell, all daughters are born rejuvenated and enjo

49 Investigation in meiosis using pollen mother cells also revealed that it is not the major comp

50 Using single budding yeast mother cell analyses we found that, even early after tel

51 Cells in which both mother-cell anchoring mechanisms have been disabled have

52 s in asymmetric prion distribution between a mother cell and a bud.

53 n asymmetric cell division, creating a large mother cell and a small forespore.

54 e development, generates two cells, a larger mother cell and a smaller forespore.

55 rically-positioned septum generates a larger mother cell and a smaller forespore.

56 to develop into two different cell types, a mother cell and a spore.

57 lly, SpoIIGA is predominantly located in the mother cell and as a consequence confines sigma(E) activ

58 Kin4 primarily localizes to the mother cell and associates with spindle pole bodies (SPB

59 ptc1Delta cells, ER tubules migrate from the mother cell and contact the bud tip, yet fail to spread

60 a multimeric membrane complex connecting the mother cell and developing spore that is required to mai

61 envelope secretion complex that connects the mother cell and developing spore.

62 Recent experiments indicating that the mother cell and forespore are joined by a channel have l

63 passage of large macromolecules between the mother cell and forespore during the feeding process.

64 specialized secretion system that links the mother cell and forespore has a complexity approaching t

65 ture, it may also form a channel between the mother cell and forespore membranes.

66 -Q complex and a hub for the localization of mother cell and forespore proteins.

67 cent cells of the developing sporangium, the mother cell and forespore.

68 complex contains a conduit that connects the mother cell and forespore.

69 cross the double membrane that separates the mother cell and forespore.

70 otubules and dynein distribution between the mother cell and its bud.

71 an SPB escapes the MEN inhibitor Kin4 in the mother cell and moves into the bud where the MEN activat

72 D is a key regulator of transcription in the mother cell and positively or negatively regulates more

73 ls divide asymmetrically, generating a large mother cell and smaller forespore.

74 lized, with different genes expressed in the mother cell and the forespore.

75 ranes to create a direct conduit between the mother cell and the forespore.

76 roximately equal numbers of molecules in the mother cell and the forespore.

77 Thus, only when a MEN bearing SPB leaves the mother cell and the spindle is accurately positioned alo

78 , defined sets of neuroblasts, many ganglion mother cells and discrete populations of neurons.

79 s, we assessed meiotic progression in pollen mother cells and found massive chromosome fragmentation

80 hat acidity of the vacuole declines in aging mother cells and limits lifespan, but that daughter cell

81 spond to transient DNA replication stress in mother cells and that a lack of telomerase accelerates o

82 in order to distinguish active and inactive mother cells and the behaviors of their daughter nuclei

83 eservoir of high-functioning mitochondria in mother cells and thereby preserves maternal reproductive

84 asymmetric cell division, leading to a large mother-cell and a small forespore compartment.

85 spindle, contributions from the shape of the mother cell, and late changes occurring between anaphase

86 ate that GerM and SpoIIIAH, derived from the mother cell, and SpoIIQ, from the forespore, have recipr

87 s during the early asymmetric divisions of a mother cell, and that preventing this decline suppresses

88 uses accumulation of circles and NPCs in the mother cell, and thereby promotes ageing.

89 omere length, finite replicative lifespan of mother cells, and survivorship.

90 termines how the cytoplasmic contents of the mother cell are partitioned into the daughter cells, and

91 ed a replicative longevity paradigm in which mother cells are moved after 15 generations on defined m

92 ess-response proteins Pdr5p and Trx2p in the mother cells are stable during the first few cell cycles

93 takes place in the terminally differentiated mother cell as offspring grow.

94 n yeast, partitioning of such circles to the mother cell at mitosis ensures their loss from the popul

95 iming to facilitate SYS-1 clearance from the mother cell at the time of asymmetric division.

96 Mother cells bearing twins are substantially longer than

97 s into the endospore, while the larger cell (mother cell) becomes a terminally differentiated cell th

98 ng spore just as forespore engulfment by the mother cell begins.

99 cerevisiae cells divide asymmetrically: the mother cell buds to produce a smaller daughter cell.

100 terns: [HXT6/7circle] normally segregates to mother cells but in low glucose is present in up to 50%

101 Pma1 accumulates in aging mother cells, but is largely absent from nascent daughte

102 Cytosolic pH increases in aging mother cells, but is more acidic in daughter cells.

103 es that induce ER stress are retained in the mother cell by activation of the ER Stress Surveillance

104 d as pro-sigma(E), which is activated in the mother cell by cleavage in response to a signal from the

105 e SpoIIGA to activate sigma(E) in the larger mother cell by processing of pro-sigma(E).

106 candidates to be long-lived and retained in mother cells by time-lapse microscopy.

107 in silencing is reported to decline in aging mother cells, causing sterility in old cells.

108 and gerO and gerQ were expressed only in the mother cell compartment during C. perfringens sporulatio

109 he regulation of developmental events in the mother cell compartment of C. perfringens is not the sam

110 ma(F) activation, sigma(E) activation in the mother cell compartment only occurs above the KinA thres

111 e anaphase spindle becomes misaligned in the mother cell compartment, cells arrest in anaphase becaus

112 If the spindle becomes mispositioned in the mother cell compartment, cells arrest in anaphase due to

113 In the absence of MciZ, the mother-cell compartment of the sporangium aberrantly for

114 is, sigma(E)-directed gene expression in the mother-cell compartment of the sporangium triggers the a

115 a(F) in the forespore and of sigma(E) in the mother cell compartments occurs via a cascade of coheren

116 differentially localize to the forespore and mother cell compartments of the sporangium during spore

117 fic protein degradation showed that only the mother cell complex is required to translocate DNA into

118 A subset of peroxisomes is retained at the mother cell cortex by the Pex3-Inp1 complex.

119 shape the cell plate as it grows toward the mother cell cortex is dependent upon a large array of pr

120 ether and show it anchors peroxisomes at the mother cell cortex, suggesting a new model for peroxisom

121 It was suggested that yeast mother cells could also differ from each other depending

122 temporally integrated throughout the entire mother cell cycle and that even a 1-hour lapse in mitoge

123 DNA damage signalling over the course of the mother cell cycle constitutes the predominant control me

124 BclA and BclB proteins are expressed in the mother cell cytoplasm and become spore-associated in a t

125 rane fission releases the forespore into the mother cell cytoplasm.

126 tex glia, and between NBs and their ganglion mother cell daughters.

127 e highly efficient trapping and retention of mother cells, determination of the replicative lifespan,

128 ed and expand, and lead to failure in pollen mother cell development.

129 f mitochondria accumulates at the tip of the mother cell distal to the bud.

130 on among the offspring was determined as the mother cell divides into daughter cells.

131 Only a tiny proportion of mother cell DNA is inherited by intracellular offspring,

132 ns provide a potential explanation for guard mother cell dormancy in soybean embryos.

133 o membranes to connect the forespore and the mother cell during endospore development in the bacteriu

134 hat daughter cells receive mitochondria from mother cells during division.

135 ther to confine protein deposit formation to mother cells during division.

136 Like their mother cells, EMP expressed molecules important for Ag p

137 eted and the dividing septum is thinned, the mother cell engulfs the forespore in a slow process base

138 During development the mother cell engulfs the forespore to produce a protoplas

139 Following asymmetric division, the mother cell engulfs the forespore, surrounding it with t

140 Subsequently, the mother cell engulfs the forespore.

141 , we investigate the mechanisms by which the mother cell engulfs the prospective spore during sporula

142 sexual reproduction initiates with megaspore mother cell entry into meiosis and formation of a tetrad

143 teracts across an intercellular space with a mother cell-expressed membrane protein, SpoIIIAH.

144 monstrated that TEX1 repressed the megaspore mother cell fate by promoting the biogenesis of TAS3-der

145 the THO complex in restricting the megaspore mother cell fate to a single cell.

146 gametes arise via meiosis of diploid pollen mother cells followed by two rounds of mitotic division.

147 division and do not typically reoccupy their mother-cell footprint, and often even disseminate their

148 olarity is a key event in the preparation of mother cells for asymmetric cell divisions that produce

149 tion of mother cell membrane proteins to the mother cell-forespore interface.

150 In this study, we show that yeast mother cells form a protein aggregate during early repli

151 f ARF3 expression limits excessive megaspore mother cell formation non-cell-autonomously.

152 During asymmetric division, a mother cell generates daughter cells that go on to adopt

153 Division of the asymmetrically growing mother cell gives rise to daughter cells that differ in

154 Asymmetric division, in which a single mother cell gives rise to daughters with distinct identi

155 We show that the mother cell gives rise to two sisters that participate e

156 A mother cell giving rise to offspring usually needs to ch

157 ll (SMC) divisions toward the adjacent guard mother cell (GMC) during stomatal development in maize (

158 g into the differentiating, smaller ganglion mother cell (GMC) where they are required for neuronal d

159 ll (SMC) divisions toward the adjacent guard mother cell (GMC), apparently under the influence of a G

160 s the identity of its daughter, the ganglion mother cell (GMC), the asymmetric division of the GMC an

161 Type I neuroblasts produce ganglion mother cells (GMCs) that divide once to produce differen

162 in neuroblasts generate a series of ganglion mother cells (GMCs) that each make two neurons (type I l

163 ions to produce a series of smaller ganglion mother cells (GMCs), which typically divide once to form

164 fate specification to daughters of ganglion mother cells (GMCs).

165 Artificial Spo0A activation blocked mother cell growth in the absence of sigma(E).

166 or sigma(G) to the action of sigma(E) in the mother cell, has remained mysterious.

167 Siblings within a mother cell have similar numbers of oriCs.

168 partitioning of molecules at cell division, mother-cell heterogeneity, and variation in cell-cycle p

169 ruction of a bud and its separation from the mother cell in Saccharomyces cerevisiae have provided fo

170 of excitatory neurons arising from the same mother cell in the developing neocortex serve as a subst

171 fates of sister cells arising from the same mother cell in the regeneration blastema.

172 notype at meiosis, but only in the megaspore mother cell in the sexual genotype.

173 embrane space that separates forespores from mother cells in endospore-forming bacteria.

174 We show that viability of mother cells in liquid culture is regulated by SIR2 and

175 e functionally segregated even within single mother cells in S. cerevisiae.

176 ng ageing are preferentially retained by the mother cell, in part through tethering to mitochondria,

177 Mother cells inheriting old poles are phenotypically dis

178 metric cell divisions in which the subapical mother cell inherits most of the vacuolar space and beco

179 a remarkable stability of growth whereby the mother cell inherits the same pole for hundreds of gener

180 llus subtilis cell-division inhibitor, MciZ (mother cell inhibitor of FtsZ), blocks assembly of FtsZ.

181 ges are generated by repeated divisions of a mother cell into a series of daughter cells, often with

182 ercellular channel allowing passage from the mother cell into the forespore of factors required for l

183 tes much of the circular chromosome from the mother cell into the forespore, but the molecular mechan

184 egulator of sigma(G) is transported from the mother cell into the forespore.

185 a regulated manner, to physically cleave the mother cell into two daughter cells.

186 It has been proposed that entry of mother cells into senescence is driven by the progressiv

187 Engulfment of the forespore by the mother cell is a universal feature of endosporulation.

188 n, indicating that the silenced state in the mother cell is inherited in daughter cells.

189 orulation process, the inner membrane of the mother cell is inverted and transformed to become the ou

190 okinesis is the final step of mitosis when a mother cell is separated into two daughter cells.

191 ells so that the clonal marker of individual mother cells is traced in the specialized progeny.

192 ression of foxp3 epigenetically, which marks mother cell iTreg lineage choice within the genome of di

193 Our results demonstrated that QDs on mother cell landscape tend to distribute among its proge

194 nism ensuring that Kin4 only associates with mother cell-located SPBs.

195 The experiment reveals that CR mother cells lose the longevity benefit of CR when evacu

196 (MEP), an inducible genetic system in which mother cells maintain a normal RLS--a median of 36 gener

197 Each division redistributes the mother cell mass along the axis of division.

198 iates endosporulation involving formation of mother cell (MC) and forespore (FS) compartments.

199 atchet" contributing to the migration of the mother cell membrane around that of the forespore in a p

200 Subsequently, the mother cell membrane engulfs the forespore in a phagocyt

201 Then, the mother cell membrane migrates around the forespore in ti

202 The mother cell membrane protein SpoIIIAH recognizes the cel

203 he forespore membrane protein SpoIIQ and the mother cell membrane protein SpoIIIAH.

204 tional cue that dictates the localization of mother cell membrane proteins to the mother cell-forespo

205 isB-cardiolipin interactions ensure that the mother cell membranes are severed at the right time and

206 tion machines function as motors pulling the mother cell membranes around the forespore.

207 After division, the mother cell membranes migrate around the forespore in a

208 pollen and seed sterility, altered Megaspore Mother Cell (MMC) specification, and delayed programmed

209 female germline is formed from the megaspore mother cell (MMC), a single cell in the premeiotic ovule

210 ivisions of stomatal stem cells (meristemoid mother cells [MMCs]) are fundamental for the generation

211 dozen transcripts that are exported from the mother-cell nucleus during mitotic anaphase, transported

212 f a channel or transporter through which the mother cell nurtures forespore development.

213 junction-like feeding tube through which the mother cell nurtures the developing spore by providing s

214 w studies indicate that retention of ERCs in mother cells occurs not by tethering to the nuclear peri

215 However, such defects are minor in mother cells of these mutants, likely because the G1 pha

216 increases the degree of reoccupation of the mother-cell outline in highly motile cells.

217 Yeast mother cells pay a sacrifice during budding: they keep t

218 ll GTPase RHO GTPASE OF PLANTS (ROP) promote mother cell polarity and subsequent division asymmetry i

219 suggest that PG degradation enables a second mother-cell-produced protein to interact with SpoIIQ.

220 e a finite replicative life span; that is, a mother cell produces only a limited number of daughter c

221 A yeast mother cell progressively ages with each cell division a

222 -dependent confinement of ER stress into the mother cell promoted aging.

223 gned spindle, mislocalization of Lte1 in the mother cell promoted loss of Bfa1 from one SPB and allow

224 ane protein SpoIIQ, which interacts with the mother cell protein SpoIIIAH at the septum to localize o

225 btilis, the forespore protein SpoIIQ and the mother cell protein SpoIIIAH form a channel, essential f

226 nism, strong ligand-receptor binding between mother-cell protein SpoIIIAH and forespore-protein SpoII

227 The forespore protein SpoIIQ and the mother-cell protein SpoIIIAH interact across the double

228 pads, used together to allow for trapping of mother cells, removal of daughter cells, monitoring grad

229 hracis spores nor the formation of spores in mother cells required UDP-GlcNAc 2-epimerase activity.

230 Retention of peroxisomes in yeast mother cells requires Inp1, which is recruited to the or

231 ites are formed sequentially within a single mother cell, requiring replication and distribution of e

232 ntially eliminated from the forespore or the mother cell, respectively.

233 anaphase due to inhibition of the MEN by the mother cell-restricted SPoC kinase Kin4.

234 hat in the rts1 mutant, Ace2 accumulation in mother cells results in Ash1 expression in mothers, and

235 During vertical apical divisions, only the mother cell retained tight junctions and segregated apic

236 Alternation between DNA replication in the mother cell (S phase) and equal partitioning of the repl

237 We find that aged mother cells show a decreased ability to initiate the me

238 y after telomerase inactivation (ETI), yeast mother cells show transient DNA damage response (DDR) ep

239 Moreover, the elder mother cells showed lower coefficient of variation for P

240 it SpoIIIAH to the sporulation septum on the mother cell side; however, the mechanism by which SpoIIQ

241 it SpoIIIAH to the sporulation septum on the mother-cell side, however the mechanism by which SpoIIQ

242 pletion of engulfment of the prespore by the mother cell, sigma(G) is activated in the prespore.

243 calized CDKG1 in pre-mitotic cells is set by mother cell size, and its progressive dilution and degra

244 of cell division may provide a link between mother cell-size and mitotic division number.

245 sion, wherein a 'counting' mechanism couples mother cell-size to cell division number allowing produc

246 es the polarization of asymmetric subsidiary mother cell (SMC) divisions during stomatal development.

247 that promotes the polarization of subsidiary mother cell (SMC) divisions toward the adjacent guard mo

248 es the polarization of asymmetric subsidiary mother cell (SMC) divisions toward the adjacent guard mo

249 vely to polarize the divisions of subsidiary mother cells (SMCs) during stomatal development in maize

250 Expression of mother cell-specific (spoIIID) and forespore-specific (s

251 e impaired in post-engulfment, forespore and mother cell-specific gene expression, suggesting a chann

252 spore-specific sigma factor sigma(F) and the mother cell-specific sigma factor sigma(E).

253 ke projections, whose formation requires the mother cell SpoIIDMP protein complex.

254 ative gene expression analyses of the pollen mother cell stage in seven diploid sexual and seven dipl

255 tal differentiation is arrested at the guard mother cell stage.

256 to the formation of supernumerary megaspore mother cells, suggesting that TEX1- and TAS3-mediated re

257 part of a channel between the forespore and mother cell that is required for the activation of sigma

258 The few aged mother cells that do enter meiosis complete this develop

259 e report that formation of tubular ER in the mother cell, the first step in ER inheritance, depends o

260 gnificantly improved retention rate of yeast mother cell, the HYAA-Chip was capable of demonstrating

261 The MEN inhibitory zone is located in the mother cell, the MEN-activating zone in the bud, and the

262 lineage, known as meristemoids, and in guard mother cells, the progenitors of stomata.

263 functions in the activation of sigmaE in the mother cell; the other (SpoIIIL) is required for sigmaG

264 fate of QDs on molecular landscape of single mother cell through several generation times (progeny ce

265 that extend from the bud tip or neck to the mother cell tip, serve as tracks for bidirectional cargo

266 tory proteins control gene expression in the mother cell to ensure proper spore formation.

267 th spindle pole bodies (SPBs) located in the mother cell to inhibit MEN signaling.

268 stable through cell divisions, from a single mother cell to its progeny during mitosis, and represent

269 asmic protein aggregates are retained in the mother cell to protect the functional capacity of daught

270 ptor Vac17 to transport the vacuole from the mother cell to the bud.

271 and terminates organelle transport from the mother cell to the bud.

272 ling is mediated by a channel that links the mother cell to the forespore.

273 Ssd1 speeds Q-cell wall assembly and enables mother cells to enter this state.

274 onuclease is expressed in late G1 in haploid mother cells to initiate mating-type interconversion.

275 s, as inhibited mating-type switching causes mother cells to shun their own daughters.

276 s NA might be exported by glucose-restricted mother cells to survive later generations, we developed

277 at progeny can send feedback signals to the 'mother' cell to modify its cell cycle status.

278 ry at cell-cycle checkpoints before mitosis, mother cells transmit DNA damage-induced p53 protein and

279 eriohopanetetrol, to remain localized to the mother cell type.

280 (SpoIIIAA through SpoIIIAH) produced in the mother cell under the control of sigma(E) are ordinarily

281 Yeast mother cells undergo a limited number of asymmetric divi

282 row from the bud neck toward the back of the mother cell until their length roughly equals the diamet

283 plasma membrane and remained robustly in the mother cell upon cell division.

284 We find that Pma1 activity antagonizes mother cell vacuole acidity by reducing cytosolic proton

285 at the molecular level and connects with the mother cell wall remains unclear.

286 monas achieves the timely degradation of its mother cell wall, a type of ECM, through the budding of

287 post-mitotic hatching of daughters from the mother cell wall.

288 Spore tetrads develop in spore mother cell walls within a mucilaginous matrix, both of

289 C. albicans budding mother cells were found to be nonadherent, which contras

290 e asymmetrically and HO is expressed only in mother cells where a nucleosome eviction cascade along t

291 sting of two chambers, the forespore and the mother cell, which are linked by pathways of intercellul

292 levels of cyclin D in the G(2) phase of the mother cell, which controls the proliferation-quiescence

293 s selected to differentiate into a megaspore mother cell, which is committed to giving rise to the fe

294 enlarges and differentiates into a megaspore mother cell, which then undergoes meiosis to give rise t

295 , led to the formation of multiple megaspore mother cells, which were able to initiate gametogenesis.

296 originate from a stalk-like extension of the mother cell whose terminal segment is gradually remodele

297 Detachment initiates in the mother cell with the phosphorylation of Vac17 that recru

298 wth could occur after asymmetric division in mother cells with no active sigma(E).

299 bearing twins are substantially longer than mother cells with single spores.

300 In growing mother cells, with no active sigma(E), Spo0A-directed tr