ライフサイエンスコーパス: motor coordination

1 rotoxicity (as tested by a rota-rod test for motor coordination).

2 used to investigate the neural circuitry of motor coordination.

3 mediators and neurotrophic factor levels and motor coordination.

4 ranslation of timing information to auditory-motor coordination.

5 automatic reflexes to spatial perception and motor coordination.

6 rtical regions involved in language and fine motor coordination.

7 anges in ANS function, locomotor activity or motor coordination.

8 in cerebellar conditioned learning and fine motor coordination.

9 mpact the normal development of language and motor coordination.

10 xploration of novel objects, locomotion, and motor coordination.

11 many nervous system functions, particularly motor coordination.

12 RPC5 knockout mice have deficits in gait and motor coordination.

13 play more severe impairments than females in motor coordination.

14 attern of sensory input specificity and thus motor coordination.

15 brain development, spontaneous movement, and motor coordination.

16 automatic reflexes to spatial perception and motor coordination.

17 nd better performance on one measure of fine motor coordination.

18 standing and walking, cognitive ability, and motor coordination.

19 to be central to the role of this system in motor coordination.

20 ontrols in the accelerating rotarod test for motor coordination.

21 of the B2-ablated mice demonstrated impaired motor coordination.

22 cognitive abilities, executive functions and motor coordination.

23 ia was observed at doses that did not affect motor coordination.

24 ined, indicating the potential complexity of motor coordination.

25 to the rescue of host PNs and restoration of motor coordination.

26 ze of the dopaminergic neurons as well as in motor coordination.

27 of CDA54 did not affect acute nociception or motor coordination.

28 f cognition, level of locomotor activity, or motor coordination.

29 ts of Delta(9)-tetrahydrocannabinol (THC) on motor coordination.

30 ding-related cognitive deficits and impaired motor coordination.

31 pecific motor deficits, namely, sedation and motor coordination.

32 e in the rotarod, pole, and cagetop tests of motor coordination.

33 eneration, myelination defects, and impaired motor coordination.

34 ctional imaging that the cerebellum supports motor coordination.

35 morphology and are impaired in cognition and motor coordination.

36 prior to ICB vehicle had no effect on normal motor coordination.

37 -expressed Punc in the cerebellar control of motor coordination.

38 revealed when increased demands were made on motor coordination.

39 d are crucial to the circuitry that controls motor coordination.

40 d-stress-induced neuronal death and improves motor coordination.

41 taleptic behaviours associated with impaired motor coordination.

42 mpaired muscle grip strength, and defects in motor coordination.

43 d reduced hyperpathic responses and improved motor coordination.

44 utes to the impairment of spatial memory and motor coordination.

45 d hyperpathic responses, along with improved motor coordination.

46 zation consists of a specific, circumscribed motor coordination.

47 brain, causing neuronal damage and affecting motor coordination.

48 process causes progressive deterioration of motor coordination.

49 ncluding cognitive decline and impairment of motor coordination.

50 ns, where regularity is believed crucial for motor coordination.

51 toxicity in a variety of behaviors including motor coordination.

52 neurons, exhibit impairments in balance and motor coordination.

53 Tight glucose control improved motor coordination (9% [95% CI, 0%-18%] to 20% [95% CI,

54 ing those for general health and metabolism, motor coordination, activity, and sleep behavior.

55 ocampus-dependent spatial learning, impaired motor coordination, altered response to novelty, and sen

56 llows researchers to quantify differences in motor coordination among genotypes of mice that may diff

57 of alcohol cause considerable impairment of motor coordination, an effect that substantially involve

58 A mice displayed a significant impairment of motor coordination and a motor learning delay.

59 IDkk1 mice show impaired motor coordination and are irresponsive to amphetamine.

60 l spontaneous mouse mutants with deficits in motor coordination and associated cerebellar neuropathol

61 o needed for mGluR1-dependent slow EPSCs and motor coordination and associates with mGluR1, GluRdelta

62 , which display macrocephaly and deficits in motor coordination and associative learning, recapitulat

63 hyperglycemia, associated with improved fine motor coordination and attention.

64 nt pattern analysis, and progressive loss of motor coordination and balance at the age of 12 months d

65 Here we assessed motor coordination and balance to investigate if deletio

66 Motor coordination and balance were more adversely affec

67 nal cord areas, motor-evoked potentials, and motor coordination and balance, we determined that axona

68 output of these cells and the regulation of motor coordination and balance.

69 FGF14 in adult Purkinje neurons also impairs motor coordination and balance.

70 Finally, motor coordination and both spontaneous and psychostimul

71 ng it with the commonly used rotarod test of motor coordination and by using eye movements to monitor

72 splicing of genes that likely contribute to motor coordination and cell survival.

73 Cerebellar motor coordination and cerebellar Purkinje cell synaptic

74 The cerebellum is critical for motor coordination and cognitive function and is the tar

75 (KO) mice display no deficits in measures of motor coordination and cognitive function but exhibit in

76 SCA1 patients lose motor coordination and develop slurred speech, spasticit

77 alcoholic beverages produces alterations in motor coordination and equilibrium that are responsible

78 Inferior olive (IO) neurons are critical for motor coordination and exhibit oscillations in membrane

79 CD4(-/-) mice showed partial restoration of motor coordination and gait that coincided temporally wi

80 ular transport; however, it enables motor-to-motor coordination and high force generation regardless

81 gative symptoms group still exhibited poorer motor coordination and higher levels of NSS, as well as

82 ause null mutations exhibit deficits in fine motor coordination and hippocampus-dependent memory.

83 NgR123-null mice displayed reduced motor coordination and hyperactivity.

84 n a progressive movement disorder, including motor coordination and imbalance, which is typical for a

85 es in vivo, resulting in hyperactivity, poor motor coordination and impaired cue-based learning in mi

86 The inferior olive plays a critical role in motor coordination and learning by integrating diverse a

87 The inferior olive plays a critical role in motor coordination and learning by integrating diverse a

88 e cerebellar cortex is centrally involved in motor coordination and learning, and its sole output is

89 tical element of the circuitry that controls motor coordination and learning.

90 otor sensitization to cocaine and attenuated motor coordination and learning.

91 Cplx1-/- mice show pronounced deficits in motor coordination and locomotion including abnormal gai

92 Sustained improvements in motor coordination and locomotor activity were observed,

93 cerebellar cortex and play a crucial role in motor coordination and maintenance of balance.

94 used strain-dependent changes in the weight, motor coordination and motor learning capability of mice

95 aphical location can change the body weight, motor coordination and motor learning capability of wild

96 Motor coordination and motor learning require an intact

97 proper connectivity of zones is critical for motor coordination and motor learning, and in several ne

98 es, they exhibited age-dependent deficits in motor coordination and motor learning.

99 of DOR using naltrindole partially improved motor coordination and normalized spatial navigation and

100 th better performance on one measure of fine motor coordination and on one measure of attention and e

101 f kinetin starting at birth improves sensory-motor coordination and prevents the onset of spinal abno

102 by more than 90%, maintain motor skills and motor coordination and reduce neuropathological hallmark

103 s of CR on outcomes such as immune function, motor coordination and resistance to sarcopenia in rhesu

104 We found that while motor coordination and reward learning were largely unch

105 urse of GD mice, with increased survival and motor coordination and salutary effects on cerebral as w

106 opaminergic drugs, and by subtle deficits in motor coordination and sensorimotor gating.

107 The cerebellum drives motor coordination and sequencing of actions at the mill

108 clei neurons targeted.SIGNIFICANCE STATEMENT Motor coordination and skilled movements are driven by t

109 ditioning, but do exhibit mild impairment of motor coordination and social discrimination.

110 nt mice are viable and have deficits in fine motor coordination and some forms of memory.

111 chlear brainstem nuclei, which contribute to motor coordination and sound processing, respectively.

112 at mice invalidated for LXRs exhibit altered motor coordination and spatial learning, thinner myelin

113 strength, sensory neglect, gait impairment, motor coordination and spatial navigation tests.

114 alities and correlated strongly with reduced motor coordination and spinal cord atrophy.

115 AKAP150 null mice also exhibit deficits in motor coordination and strength that are consistent with

116 post-injection but may induce impairment of motor coordination and striatal atrophy.

117 acemaking in Purkinje cells is essential for motor coordination and suggest that K(Ca) channels may c

118 eflexive responding, as well as for impaired motor coordination and the higher brain functions of lea

119 e the first to describe a role for RGS9-2 in motor coordination and working memory and implicate RGS9

120 ents could potentially contribute to loss of motor coordination and, thus, pharmacological manipulati

121 al haploinsufficiency altered self-grooming, motor coordination, and apparent motivation in operant c

122 are also hyperactive at night, have reduced motor coordination, and are thigmotactic compared with c

123 l as their wild-type littermates in tests of motor coordination, and both showed aging-related decrea

124 were associated with poorer attention, fine motor coordination, and cognition in the CHAMACOS cohort

125 eficits in spatial learning/memory, impaired motor coordination, and decreased sociability by 4 month

126 logies, such as learning and memory, reward, motor coordination, and Down syndrome.

127 est of Visual-Motor Integration); attention, motor coordination, and executive functions (Amsterdam N

128 ts in motor skills, including grip strength, motor coordination, and gait and also related defects in

129 eatment also improved pancreatic morphology, motor coordination, and increased life span.

130 communication and social behaviors, impaired motor coordination, and increased stress reactivity and

131 Hypothalamic gene transcription, motor coordination, and life span were also determined.

132 te that the tVTA controls rotation behavior, motor coordination, and motor skill learning.

133 ly, transient improvement in attention, fine motor coordination, and reported well-being were observe

134 that are essential for vision, nociception, motor coordination, and reward processing.

135 tor deficits such as akinesia, bradykinesia, motor coordination, and sensorimotor neglect after unila

136 s include severe mental retardation, loss of motor coordination, and sleep disturbances.

137 macroorchidism, anxiety, mental retardation, motor coordination, and speech articulation deficits.

138 pectively, development of laminar structure, motor coordination, and synapse formation.

139 ard motor tests for balance and appendicular motor coordination, and used a novel long-term fluid-lic

140 repeated measures of attention, memory, fine motor coordination, and well-being.

141 were hyperactive, displayed a subtle lack of motor coordination, and were generally more anxious than

142 ith significant improvements in brain edema, motor coordination, and working memory, and abrogated ne

143 sex-specific disruptions to activity levels, motor coordination, anxiety-related behavior and social

144 re of particular interest for their roles in motor coordination, appetitive, and aversive behavior, a

145 ad increased locomotor activity and impaired motor coordination as juveniles (P35) and young adults (

146 ed to contribute to the observed deficits in motor coordination as well as in learning and cognitive

147 ry and vestibular information processing and motor coordination, as do MHB-derived circuits in verteb

148 In addition, young AS mice have defects in motor coordination, as well as abnormal brain activity t

149 progressive hind leg weakness and decline in motor coordination at 12 to 16 months of age, followed b

150 began to manifest hyperactivity and abnormal motor coordination at 2 weeks of age but were indistingu

151 ficient for PC-specific Mof display impaired motor coordination, ataxia, a backward-walking phenotype

152 rvive, and surviving mice exhibited impaired motor coordination, audiogenic seizures, and brainstem n

153 Lesioned mice showed normal motor coordination, balance, and general locomotion.

154 cerebellar function is paramount for proper motor coordination, balance, and motor learning.

155 d repetitive behaviors without alteration of motor coordination, balance, or locomotion.

156 t severe difficulties in social interaction, motor coordination, behavioral flexibility, and atypical

157 Interpersonal motor coordination between dyads of patients (n = 45) or

158 re involved in the ataxic null phenotype and motor coordination, but not motor learning.

159 early age and develop a significant loss of motor coordination by 24 weeks of age.

160 eficits: progressive imbalance and decreased motor coordination by 50 weeks, gait deficits by 60 week

161 We propose that these adjustments preserve motor coordination by allowing one subunit to make perio

162 ) rats strongly suggest that alcohol impairs motor coordination by enhancing granule cell tonic inhib

163 We find that alcohol impairs motor coordination by enhancing tonic inhibition mediate

164 egenerative disorder that results in loss of motor coordination caused primarily by a disruption of c

165 bellar cortex is associated with deficits in motor coordination characteristic of ataxia, effects whi

166 generative disease characterized by abnormal motor coordination, cognitive decline and psychiatric di

167 gating, anxiety, hypoactivity, and decreased motor coordination, compared to littermate controls.

168 Furthermore, functional recovery of motor coordination correlated strongly with the percenta

169 on behavioral assays that require extensive motor coordination correlated with tau pathology in corr

170 ion of Htt-Q128 leads to progressive loss of motor coordination, decreased lifespan, and time-depende

171 soluble CX3CL1 isoform reduces impairment of motor coordination, decreases dopaminergic neuron loss,

172 , CKA-deficient flies exhibit PP2A-dependent motor coordination defects.

173 ehaviour could be rescued, while anxiety and motor coordination deficit could not be recovered in adu

174 ndrocytes (Plp-Nf1 (fl/+) mice) results in a motor coordination deficit.

175 that recapitulate aspects of SCA11 including motor coordination deficits and defects to Purkinje cell

176 f mutant, a structural change that generates motor coordination deficits and impaired postural phenot

177 recently reported that long term memory and motor coordination deficits are also present in our expe

178 dministered baclofen also showed exaggerated motor coordination deficits compared with their wild-typ

179 m reduces ATXN1 levels in vivo and mitigates motor coordination deficits in a mouse model of SCA1.

180 It is believed that balance and motor coordination deficits in FXS patients are caused b

181 n through choline supplementation attenuates motor coordination deficits in the mutant offspring.

182 Cs reduces their activity and contributes to motor coordination deficits prior to Abeta aggregation a

183 and visual memory impairment as well as the motor coordination deficits which persisted after succes

184 +)) mice rescues respiratory, cognitive, and motor coordination deficits, and induces an anxiolytic e

185 tive mutant mice displayed severe ataxia and motor coordination deficits, but did not develop any tum

186 This MeCP2 overexpression line shows motor coordination deficits, heightened anxiety, and imp

187 ion immediately after injury coinciding with motor coordination deficits.

188 opment, altered intracellular signaling, and motor coordination deficits.

189 ion with shorter, thinner myelin sheaths and motor coordination deficits.

190 T1 as well as Fth KO mice showed substantial motor coordination deficits.

191 In addition, these mice also exhibit motor-coordination deficits, hypersensitivity to heat, n

192 that adult Pclo(gt/gt) rats display impaired motor coordination, despite adequate performance in task

193 The authors examined whether motor coordination difficulties assessed in childhood pr

194 cal symptoms and neuropathologies, including motor coordination disorder, cerebellar atrophy, neurona

195 t3gal2/3 double-null mice displayed impaired motor coordination, disturbed gait, and profound cogniti

196 eneous, characterized by loss of balance and motor coordination due to dysfunction of the cerebellum

197 There was no change in the normal motor coordination due to intracerebellar pretreatment w

198 s one such disease, characterized by loss of motor coordination due to the degeneration of cerebellar

199 al feedbacks elicited by a humanoid robot on motor coordination during a human-robot interaction.

200 ctions via CF6 neurons are not essential for motor coordination during either simple or complex locom

201 that somatosensory feedback is necessary for motor coordination during grasping.

202 icited by a humanoid robot to modulate their motor coordination during human-robot interaction, partl

203 to understand the molecular underpinnings of motor coordination during IFT in vivo.

204 ccelerating rotarod in females, and improved motor coordination during pole climbing in male mice.

205 ctions via CF6 neurons are not essential for motor coordination during postural corrections.

206 he effect of providing tactile perception on motor coordination during routine grasping and grasping

207 on of specific neuronal networks involved in motor coordination, emotions, and cognition.

208 es specific behavioral phenotypes, including motor coordination, episodic memory impairments, and syn

209 rsening of motor performance, with increased motor coordination errors.

210 needed for cerebellar synaptic function and motor coordination, explaining the shared cerebellar mot

211 ediates multifaceted sensory integration and motor coordination functions.

212 astroglia Ca(2+) activation does not affect motor coordination, global suppression of astroglial net

213 ments, including hypolocomotion, deficits in motor coordination, impaired learning of new motor routi

214 MPTP-induced pathologies, exhibiting similar motor coordination impairment, dopaminergic neuron loss,

215 swim test, reduced prepulse inhibition, mild motor coordination impairments and reduced grip strength

216 pinal motoneuronal somatotopic organization, motor coordination implies interactions among distant sp

217 he brain and optic nerve, as well as in poor motor coordination in a pattern consistent with the obse

218 found sex-specific differences in weight and motor coordination in both mouse strains.

219 lel fiber-Purkinje cell (PF-PC) synapses and motor coordination in developing mice.

220 ature and extent of deficiencies in bimanual motor coordination in individuals with agenesis of the c

221 unction of midbrain circuits for balance and motor coordination in insects and mammals.

222 tion and for muscle strength, endurance, and motor coordination in mice in vivo.

223 )-tetrahydrocannabinol-induced impairment of motor coordination in mice.

224 e immunotherapy leads to some improvement in motor coordination in SCA1 mice and to a modest increase

225 rkinje cells representing the source for all motor coordination in the cerebellar cortex.

226 social feedback had a facilitatory effect on motor coordination in the control participants compared

227 rtex, encode the timing signals required for motor coordination in their firing rate and activity pat

228 proposed to function as a timing device for motor coordination in which inferior olivary neurons act

229 nts favor a mechanical competition model for motor coordination in which the IFT motors exert a BBS p

230 unction and social recognition, and improves motor coordination in young male Mecp2-null (Mecp2(-/y))

231 behavioral phenotype revealed impairments in motor coordination, increased startle response to acoust

232 t serve the critical function of integrating motor coordination information with multimodal associati

233 expressed in the brain and is implicated in motor coordination, innate fear behavior, and seizure ge

234 Motor coordination is broadly divided into gross and fin

235 This aspect of motor coordination is controlled by inhibitory neurons i

236 Together these studies suggest that motor coordination is reliant on maintaining the correct

237 Motor coordination is supported by an array of highly or

238 The cerebellum, a crucial center for motor coordination, is composed of a cortex and several

239 ediated excitotoxicity, (iii) impairments in motor coordination, (iv) temporally distinct abnormaliti

240 While GoC inhibition is essential for normal motor coordination, little is known about the circuit dy

241 battery of neurobehavioral tests to evaluate motor coordination, locomotion, and cognitive function i

242 a2 mice did not show any difference in basal motor coordination, locomotor activity, or conditioned p

243 We discuss the possible motor coordination mechanism consistent with motor regul

244 dence that its function was critical for the motor coordination mechanism.

245 re sensitive to water loss, losing water and motor coordination more rapidly in desiccating condition

246 bellum, including sensory-motor integration, motor coordination, motor learning and timing.

247 ety (elevated plus maze and light/dark box), motor coordination (narrow bean traverse and gait), and

248 al structures that participate in this audio-motor coordination network in professional pianists and

249 This was accompanied by an improvement in motor coordination, neurological phenotypes, and increas

250 verse neuronal networks required for memory, motor coordination, neuronal survival, and differentiati

251 her normal mechanical or thermal thresholds, motor coordination, nor locomotor activity.

252 dy, we observed profound improvements in the motor coordination of AMI-treated N171-82Q HD model mice

253 This molecule did not impair the motor coordination of animals in the chimney test even a

254 RGS9 knockout (KO) mice have decreased motor coordination on the accelerating rotarod and defic

255 Although changes in motor coordination or anxiety cannot explain the dissoci

256 Problems with speech may reflect motor coordination or apraxia, problems with processing

257 Here we study motor coordination (or synchronisation) in a group of in

258 motion in the neonatal mouse or change gait, motor coordination, or grip strength in adult mice of bo

259 ficant impairments in neurological reflexes, motor coordination, pain sensitivity, and prepulse inhib

260 As a probe, we used a classic motor coordination paradigm exhibiting well described mo

261 rt at 5 and 7 years of age, with poorer fine motor coordination-particularly in the nondominant-at bo

262 ization between participants suggesting that motor coordination partly underlies patients' social int

263 t disorder, executive function deficits, and motor coordination problems.

264 sease with respect to weight loss, decreased motor coordination, Purkinje cell death, lipid storage,

265 preservation of executive function and fine motor coordination (r = 0.68 to 0.88).

266 exon skipping for more than a year, improved motor coordination, reduced histopathology in Cln3(Delta

267 Understanding cerebellar contributions to motor coordination requires deeper insight into how the

268 of key neurophysiological functions, such as motor coordination, respiratory control, muscle tone and

269 GlyR are involved in motor coordination, respiratory rhythms, pain transmissi

270 ssing short hairpin RNAs profoundly improved motor coordination, restored cerebellar morphology and r

271 movement but also hint at a wider variety of motor coordination roles.

272 Neuroinflammation, motor coordination (rotarod), and depressive behaviors (

273 These include poor motor coordination, sensory perceptual difficulties and

274 nt but not for sensorimotor gating, anxiety, motor coordination, several forms of learning or social

275 gative symptoms exhibited significantly more motor coordination signs and total NSS than patients wit

276 in gait problems and difficulties with basic motor coordination skills.

277 Alterations in learning, memory, motor coordination, social behavior, and stress response

278 CPTX restored synaptic functions, motor coordination, spatial and contextual memories, and

279 r synchronization partners with a measure of motor coordination stability.

280 R4-/-) mice exhibited behavioral deficits in motor coordination, suggesting impaired cerebellar funct

281 deleted in only Purkinje cells had a loss of motor coordination that was almost identical to the tota

282 V408A/+ mice showed stress-induced loss of motor coordination that was ameliorated by acetazolamide

283 In addition to its well established role in motor coordination, the cerebellum has been hypothesized

284 hat climbing fibre signals are important for motor coordination, the mechanisms by which neurones in

285 Further 42 did not affect motor coordination up to doses of 1000 mg/kg, demonstrat

286 ct liability was determined by assessment of motor coordination using the rotarod test.

287 le of cerebellar Kv3.1 and Kv3.3 channels in motor coordination was examined with an emphasis on the

288 Motor coordination was not altered.

289 sent in schizophrenia patients, whose social-motor coordination was similarly impaired in social and

290 ests of memory, executive function, and fine motor coordination, was correlated to magnetic resonance

291 To examine motor coordination, we purified neuronal transport vesic

292 her scores on tests of cognitive ability and motor coordination were associated with better performan

293 y, changes in activity-related behaviour and motor coordination were observed following CNO administr

294 E STATEMENT The neural bases of intersubject motor coordination were studied by recording cell activi

295 Fall latencies in the rotorod test of motor coordination were unaffected by systemic administr

296 epp(-/-) mice lost weight and developed poor motor coordination when fed diets with selenium below 0.

297 Behavioral testing revealed normal motor coordination, whereas all mice receiving verum tre

298 engaged in bilateral sensory integration and motor coordination, whereas lower coordination across he

299 Jebsen-Taylor hand-function test, upper arm motor coordination with the finger-nose test, and grip s

300 contralesional paretic forelimb and improved motor coordination without influencing spontaneous locom