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1 t on mucociliary function (cilia beating nor mucociliary clearance).
2   Thus, gliding may be necessary to overcome mucociliary clearance.
3 tory agents, and new approaches that improve mucociliary clearance.
4 logical changes consistent with insufficient mucociliary clearance.
5 ysical forces such as coughing, sneezing and mucociliary clearance.
6 retory epithelial cells that are involved in mucociliary clearance.
7 ce liquid (ASL) volume and the efficiency of mucociliary clearance.
8  ciliary structure and function and impaired mucociliary clearance.
9 Nase reduces airflow obstruction or improves mucociliary clearance.
10 he main epithelial functions involved in the mucociliary clearance.
11 , cytotoxicity, cilia beating frequency, and mucociliary clearance.
12 cellular composition and loss of coordinated mucociliary clearance.
13 r understand disease-specific impairments in mucociliary clearance.
14 minished transepithelial anion secretion and mucociliary clearance.
15 onal ciliated epithelium to allow for normal mucociliary clearance.
16 d function of motile cilia causes failure of mucociliary clearance.
17 y respond to defects in ciliary motility and mucociliary clearance.
18 causing reduced antimicrobial properties and mucociliary clearance.
19 racterized by mucus accumulation and reduced mucociliary clearance.
20 l defensive roles in pathogen entrapment and mucociliary clearance.
21 Pb in the stomach within 4 h, presumably via mucociliary clearance.
22  as well as airway surface liquid volume and mucociliary clearance.
23 e production to increase ciliary beating and mucociliary clearance.
24 B48 and HCoV-OC43, altered cilia beating and mucociliary clearance.
25 s ciliary beat frequency (CBF) and speeds up mucociliary clearance.
26 es with improved airway hydration status and mucociliary clearance.
27 defects in ciliogenesis and complete loss of mucociliary clearance.
28 disorders that are characterized by impaired mucociliary clearance.
29 x1) channels to release ATP, which regulates mucociliary clearance.
30  across the lung mucosal barrier, as well as mucociliary clearance.
31  respiratory dysfunction caused by defective mucociliary clearance.
32 tional motility that is essential for proper mucociliary clearance.
33 ated with altered mucus rheology and reduced mucociliary clearance.
34 tributes to CF lung disease by impairment of mucociliary clearance.
35 n of bronchial lymphoid tissue and decreased mucociliary clearance.
36       Recently, we demonstrated that reduced mucociliary clearance, a characteristic feature of asthm
37 ased amounts of and/or abnormal mucus impair mucociliary clearance, a key defense against inhaled and
38  the well-described physical barrier and the mucociliary clearance, a variety of systems, including t
39       It is hypothesized that alterations in mucociliary clearance, abnormalities in the sinonasal ep
40 cells promotes purinergic receptor-regulated mucociliary clearance activities necessary for innate lu
41 vironment, diminished cough reflex, impaired mucociliary clearance, altered alveolar macrophage funct
42 ne regulates epithelial functions supporting mucociliary clearance, an important airway defense mecha
43  Management strategies, including augmenting mucociliary clearance and aggressively treating infectio
44 lammatory cell recruitment, mucus secretion, mucociliary clearance and airway surface liquid composit
45 id transit in the gastrointestinal tract, or mucociliary clearance and alveolar macrophage uptake in
46 nsport, producing dehydrated mucus, impaired mucociliary clearance and an opportune environment for c
47 nnate immune activity has been attributed to mucociliary clearance and antimicrobial polypeptides of
48 impairs key host defense mechanisms, such as mucociliary clearance and bacterial killing in CF airway
49  fibrosis (CF) is characterized by defective mucociliary clearance and chronic airway infection by a
50 rategies have evolved in the airways such as mucociliary clearance and cough.
51 t NO production, resulting in stimulation of mucociliary clearance and direct antibacterial effects.
52 nasal residence time but also minimizing the mucociliary clearance and enzymatic degradation.
53 l and nasopharyngeal gland deficits, reduced mucociliary clearance and impaired auditory tube gating
54 o clinical consequences on respiratory-tract mucociliary clearance and lung function, fertility, and
55  include loss of lysozyme secretion, reduced mucociliary clearance and overgrowth of nasal commensal
56 ds secrete copious mucus strands to increase mucociliary clearance and protect the lung.
57 ier in the airway in order to overcome rapid mucociliary clearance and reach the underlying epitheliu
58 ftor/ivacaftor, improve airway hydration and mucociliary clearance and reduce pathogen CF acquisition
59 cerebrospinal fluid flow, sensory reception, mucociliary clearance and renal physiology indicate that
60 p uniquely allows dynamic in vivo imaging of mucociliary clearance and steady-state immune cell behav
61 opment of fetal and neonatal lung, affecting mucociliary clearance and Th1 responses.
62 tion accompanies ciliary motion defects, but mucociliary clearance and vectorial infection spread res
63 lytic treatment loosens mucus mesh, enhances mucociliary clearance, and abolishes airway hyperreactiv
64 echanisms of airway surface fluid secretion, mucociliary clearance, and adequate immune response to e
65 ability, stimulate mucus secretion, decrease mucociliary clearance, and appear capable of recruiting
66 CFTR) protein function on airway physiology, mucociliary clearance, and establishment of Pseudomonas
67 mechanisms including antimicrobial peptides, mucociliary clearance, and phagocytic cells.
68 ration, causing mucus dehydration, decreased mucociliary clearance, and recurrent acute bacterial inf
69 of LABA/LAMA combinations on hyperinflation, mucociliary clearance, and symptom severity may all cont
70 on, excessive mucus production with impaired mucociliary clearance, and symptom severity.
71                           On the other hand, mucociliary clearance appeared to play a less prominent
72 enefit have been inconclusive and effects on mucociliary clearance are unknown.
73 nefit have been inconclusive, and effects on mucociliary clearance are unknown.
74 tion and suggests therapeutic improvement of mucociliary clearance as a novel treatment strategy for
75                         These data show that mucociliary clearance associated with mild chronic bronc
76                                    Defective mucociliary clearance associated with the absence of the
77 d the structure of motile cilia and impaired mucociliary clearance, barrier function, and epithelial
78 easured tracheal mucus velocity, a marker of mucociliary clearance, before and for 8 hours after anti
79                         Substudies evaluated mucociliary clearance, beta-adrenergic sweat secretion r
80  characterized by abnormal ion transport and mucociliary clearance, but TGF-beta1 is also associated
81 particular, epithelial mucins facilitate the mucociliary clearance by physically trapping inhaled mic
82 particular, epithelial mucins facilitate the mucociliary clearance by physically trapping the inhaled
83                                 The rates of mucociliary clearance by pretreatment with amiloride and
84 eating machines that play a critical role in mucociliary clearance, cerebrospinal fluid movement, and
85 ay mucus to mediate the critical function of mucociliary clearance, cleansing the airways of inhaled
86                                     Impaired mucociliary clearance contributes to the pathophysiology
87     However, shorter drug retention time and mucociliary clearance curtail the efficiency of the intr
88  PCD-associated phenotypes of hydrocephalus, mucociliary clearance defects in the upper airway, and a
89 onic obstructive pulmonary disease and other mucociliary clearance defects.
90                                    Effective mucociliary clearance depends on adequate airway hydrati
91                          Later in infection, mucociliary clearance deteriorates.
92 an Multicilin that cause a severe congenital mucociliary clearance disorder due to reduced generation
93 on of multiple motile cilia (RGMC) is a rare mucociliary clearance disorder.
94 lial cell dysfunction, cilia shortening, and mucociliary clearance disruption.
95                                              Mucociliary clearance, driven by the engine of ciliary b
96 ic mechanisms associated with alterations in mucociliary clearance, epithelial barrier function, and
97 ed UTP and amiloride in combination improved mucociliary clearance from the peripheral airways of the
98 heterogeneous cellular population as well as mucociliary clearance functions of the in vivo nasal epi
99 stal axis to meet local functional needs for mucociliary clearance, hydration, host defense, and gas
100                   However, it is unclear how mucociliary clearance impacts SARS-CoV-2 spread after in
101           Inhaled hypertonic saline enhances mucociliary clearance, improves lung function, and reduc
102 volume of airway surface liquid, we measured mucociliary clearance in 16 normal subjects after inhala
103 ar ATP and its metabolite adenosine regulate mucociliary clearance in airway epithelia.
104                                              Mucociliary clearance in conducting airways, reduction o
105 ed airway surface liquid volume and impaired mucociliary clearance in cystic fibrosis, FOXI1-KO and F
106 ne signaling molecules led to an increase in mucociliary clearance in explanted tracheae that was Trp
107 r agonist, is effective at acutely enhancing mucociliary clearance in healthy, nonsmoking adults.
108                                 The impaired mucociliary clearance in individuals with Cystic Fibrosi
109                                              Mucociliary clearance in mammalian respiratory airways d
110 let cell metaplasia and diminishes efficient mucociliary clearance in mice with AAD, resulting in inc
111 There is no evidence for a primary defect in mucociliary clearance in most patients with CRS.
112 iquid are associated with increased rates of mucociliary clearance in normal subjects.
113 he rheology of airway secretions and enhance mucociliary clearance in patients with CF.
114 se) reduces airflow obstruction and improves mucociliary clearance in patients with cystic fibrosis (
115 treatments that restore ciliary activity and mucociliary clearance in PCD patients.
116       Dysfunction of motile cilia can impair mucociliary clearance in the airway and result in primar
117  (CFTR), which regulates anion transport and mucociliary clearance in the airways.
118  experience demonstrates that restoration of mucociliary clearance in the lungs after transplantation
119                                           If mucociliary clearance in the respiratory epithelium is s
120 ted information on its actions on the airway mucociliary clearance in vivo.
121 pertension (in Liddle syndrome) and impaired mucociliary clearance (in cystic fibrosis).
122 nce and tracheal mucus velocity, a marker of mucociliary clearance, in allergic and nonallergic sheep
123 n tracheal mucus velocity (TMV), a marker of mucociliary clearance, in sheep and (2) if the ET-1-indu
124 mucus clearance (tracheal mucus velocity and mucociliary clearance), inhaled ETX001 was able to accel
125 s infection in the conducting airways, where mucociliary clearance inhibits pathogen penetration.
126   We find that inhalation of dry air impairs mucociliary clearance, innate antiviral defense, and tis
127                                              Mucociliary clearance is a vital defense mechanism of th
128                                              Mucociliary clearance is composed of three components (i
129                                              Mucociliary clearance is determined by ciliary activity
130                                              Mucociliary clearance is one of the major lines of defen
131                                              Mucociliary clearance is one of the major lines of defen
132 icate that the antigen-induced impairment of mucociliary clearance is partly dependent on increased e
133                                              Mucociliary clearance is the primary defense mechanism i
134 motile cilia and flagella govern respiratory mucociliary clearance, laterality determination and the
135            In cystic fibrosis (CF), impaired mucociliary clearance leads to chronic infection and inf
136 r did not improve sweat chloride, whole lung mucociliary clearance, lung function or respiratory symp
137 r did not improve sweat chloride, whole-lung mucociliary clearance, lung function, or respiratory sym
138 ient subgroup of RA suggests that diminished mucociliary clearance may underlie repeated asthma exace
139 cal airway dilation associated with impaired mucociliary clearance, may occur sporadically or as a co
140                                          The mucociliary clearance (MC) system is a vital host defens
141 es within the airway surface liquid regulate mucociliary clearance (MCC) activities, the primary inna
142 ondrial iron loading, showed impaired airway mucociliary clearance (MCC) and higher pulmonary inflamm
143  the conditional deletion of Gas2l2 impaired mucociliary clearance (MCC) and led to mucus accumulatio
144                                              Mucociliary clearance (MCC) assays in CF ferrets further
145 drial dysfunction, airspace enlargement, and mucociliary clearance (MCC) disruption during CS exposur
146 AC6 inhibitor were protected from CS-induced mucociliary clearance (MCC) disruption.
147 tides are among the most potent mediators of mucociliary clearance (MCC) in human lungs.
148                                              Mucociliary clearance (MCC) in subjects with CB was nega
149                                              Mucociliary clearance (MCC) is a critical host innate de
150                                  Respiratory mucociliary clearance (MCC) is a key defense mechanism t
151                                              Mucociliary clearance (MCC) is a major airway host defen
152                                              Mucociliary clearance (MCC) is the primary physical airw
153                        The efficiency of the mucociliary clearance (MCC) process that removes noxious
154 us barrier traps and eliminates them through mucociliary clearance (MCC).
155 port to adjust ASL volume to maintain proper mucociliary clearance (MCC).
156  nearly sterile lower respiratory tract when mucociliary clearance mechanisms are functioning effecti
157 tentiation on epithelial fluid secretion and mucociliary clearance.Methods: The effects of a novel lo
158  Rimantadine had no effect on nasal patency, mucociliary clearance, nasal signs, or on symptoms and s
159 ects of inhaled vehicle and UTP/amiloride on mucociliary clearance of [99mTc] iron oxide particles fr
160      Mucin MUC5AC plays an important role in mucociliary clearance of bacterial pathogens.
161 a chloride channel that is essential for the mucociliary clearance of respiratory pathogens in humans
162 me, effects that would be proposed to reduce mucociliary clearance of respiratory pathogens.
163 structural attributes that provide effective mucociliary clearance of the lower airspace, the airway
164                                              Mucociliary clearance of whole and peripheral lung was i
165  cycle in the propagation of purine-mediated mucociliary clearance on human airway epithelial surface
166                     Defects in components of mucociliary clearance or barrier integrity are associate
167 ollowing inhalation of 99mTc aerosol, or for mucociliary clearance or the rate of clearance of the ra
168                  Significant improvements in mucociliary clearance (P < 0.001), gastrointestinal pH (
169 mately 1.4% per minute) approached the rapid mucociliary clearance rates (approximately 2.0% per minu
170        Pretreatment with amiloride increased mucociliary clearance rates (approximately twofold) afte
171                                Subsequently, mucociliary clearance rates were measured by gamma scint
172 mbrane nucleotide-release coordinates airway mucociliary clearance responses (mucin and salt, water s
173 tion of Splunc1 in mouse airways affects the mucociliary clearance, resulting in decreased innate imm
174 ss mucin production, however, overwhelms the mucociliary clearance, resulting in defective mucosal de
175 ed culture consists of various cell types, a mucociliary clearance system, and tight junctions, repre
176 tion; excessive mucus secretion and impaired mucociliary clearance that leads to airflow obstruction
177    Mucin 5B (MUC5B) has an essential role in mucociliary clearance that protects the pulmonary airway
178 nts exhibited mucus obstruction and abnormal mucociliary clearance that resemble the airway defects a
179                                              Mucociliary clearance, the physiological process by whic
180 from human airway epithelial cells regulates mucociliary clearance through cell surface nucleotide re
181 ienced any adverse effects, nor increases in mucociliary clearance time.
182 an inherited disorder that leads to impaired mucociliary clearance, to repeated chest infections, and
183 ist, isoproterenol synergistically increased mucociliary clearance velocity (MCCV) in ferret tracheas
184                                              Mucociliary clearance was measured using gamma scintigra
185                       A 2.5-fold increase in mucociliary clearance was seen in response to UTP alone
186                                              Mucociliary clearance was slowed 4 hours postchallenge i
187 acheal mucus velocity, an in vivo measure of mucociliary clearance, was also reduced by e-cig vapor.
188 onstriction is associated with impairment of mucociliary clearance with a time course that is consist
189 rosolized UTP +/- amiloride clearly enhances mucociliary clearance without acute adverse effects in n
190                  To test the hypothesis that mucociliary clearance would increase after inhalation of

 
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