ライフサイエンスコーパス: multiple round of

1 ATP hydrolysis recycles XKCM1/XKIF2 for multiple rounds of action by dissociating a XKCM1/ XKIF2

2 ng GFP and, after nearly 2 mo of culture and multiple rounds of activation, analyzed the resulting in

3 ed to mediate a fast reassociation, enabling multiple rounds of activation.

4 gence of subtype-specific inhibitors through multiple rounds of adaptation and counter-adaptation.

5 molecules along these binding sites required multiple rounds of adenosine triphosphate (ATP) hydrolys

6 However, most therapeutics require multiple rounds of administration and can have toxic sid

7 -interacting protein (HHIP) and subjected to multiple rounds of affinity maturation through the scree

8 ative end stage of replicative senescence by multiple rounds of Ag-driven cell division.

9 in cell cultures of CD8(+)CD28(+) following multiple rounds of Ag-driven proliferation, reaching the

10 ion of the Escherichia coli host cells; (ii) multiple rounds of an intracellular selection process to

11 hibit long-term self-renewal capacity during multiple rounds of androgen-mediated regeneration after

12 grammatic relevance of this evaluation after multiple rounds of antibiotic treatments is unclear.

13 tination of distributive substrates requires multiple rounds of APC binding, which render it sensitiv

14 sts are the CNS progenitor cells and undergo multiple rounds of asymmetric cell division, ;budding of

15 SecA performs multiple rounds of ATP hydrolysis before dissociating fr

16 re the enzyme binds to the DNA and catalyzes multiple rounds of ATP hydrolysis before dissociating.

17 ur data also show that MuB does not catalyze multiple rounds of ATP hydrolysis while remaining bound

18 ains associated with the microtubule through multiple rounds of ATP hydrolysis.

19 ng among different open states by undergoing multiple rounds of ATP hydrolysis.

20 folding rate enhancements without undergoing multiple rounds of ATP-induced binding and release from

21 are shifted to low Mg(++) , PhoQ engages in multiple rounds of autophosphorylation and phosphotransf

22 tasis, and function of B lymphocytes involve multiple rounds of B-cell receptor (BCR)-controlled prol

23 Five RCTs with multiple rounds of biennial screening with guaiac-based

24 icating that single EB1 molecules go through multiple rounds of binding and dissociation during micro

25 GR can undergo multiple rounds of binding and dissociation to the palin

26 ubunits of GroEL, and might help explain why multiple rounds of binding and hydrolysis are required f

27 uires both GroEL and GroES, and proceeds via multiple rounds of binding and release.

28 cord with the iterative annealing mechanism, multiple rounds of binding, partial unfolding, and relea

29 For BioB to catalyze multiple rounds of biotin synthesis, the [2Fe-2S](2+) cl

30 nd the variable length of each gene requires multiple rounds of BLAST searches for a single IG sequen

31 imple example of processivity, as defined by multiple rounds of catalysis without release of substrat

32 at this conformational change is stable over multiple rounds of catalysis.

33 rred from one reaction to another to achieve multiple rounds of catalysis.

34 Transient TCR stimulation induces multiple rounds of CD8 T cell division without further r

35 evolution of an oligonucleotide pool through multiple rounds of CE-SELEX selection against the target

36 er the signal appears, proliferating through multiple rounds of cell division before committing to a

37 least 1000-fold, HA-specific T cells undergo multiple rounds of cell division before reaching a nonre

38 l status of a gene can be maintained through multiple rounds of cell division during development.

39 ergy avoidance: the few T cells that undergo multiple rounds of cell division during overt CD28 costi

40 CD4(+) T cells that undergo multiple rounds of cell division during primary Ag chall

41 does not rely on candidate markers to track multiple rounds of cell division in vivo.

42 og-based lineage-tracing technique to detect multiple rounds of cell division in vivo.

43 strated evidence of blastogenesis, underwent multiple rounds of cell division leading to their clonal

44 ed Otx/bHLH pathway act sequentially through multiple rounds of cell division on the right to relay a

45 ribution of intracellular nanoparticles upon multiple rounds of cell division was investigated.

46 h) to Ag and B7-1 is sufficient to stimulate multiple rounds of cell division, but clonal expansion a

47 When this process is repeated during multiple rounds of cell division, it leads to patterns o

48 f genome integrity is key for the success of multiple rounds of cell division.

49 ic cells, while long-term memory can survive multiple rounds of cell division.

50 late diverse mutations in a DNA barcode over multiple rounds of cell division.

51 same domain that is stably inherited through multiple rounds of cell division.

52 d to specify a variety of cell types through multiple rounds of cell divisions or to exert seemingly

53 The liver is a complex organ that requires multiple rounds of cell fate decision for development an

54 tor in transfected cells in combination with multiple rounds of cell selection and single-cell clonin

55 in-dependent kinase 2 (Cdk2) is required for multiple rounds of centrosome duplication in Xenopus egg

56 Multiple rounds of centrosome reproduction were blocked

57 the sensitive A2780S ovarian cancer line to multiple rounds of cisplatin treatments followed by reco

58 The transferrin receptor (TfR) undergoes multiple rounds of clathrin-mediated endocytosis and ree

59 erved in prostate cancer may be explained by multiple rounds of clonal expansion.

60 l initiation is a cyclical process involving multiple rounds of coactivator assembly and disassembly.

61 By performing multiple rounds of counter selections with WT and cataly

62 equires that Vps10p must recycle and perform multiple rounds of CPY sorting.

63 After multiple rounds of cycling mutagenesis and DNA shuffling

64 with RAF1 membrane localization, may involve multiple rounds of cytosolic RAF1 rebinding to active RA

65 The colonic epithelium can undergo multiple rounds of damage and repair, often in response

66 ure sufficient amino acids are available for multiple rounds of daughter generation.

67 However, multiple rounds of degeneration/regeneration in conditio

68 ontrols) were given azoxymethane followed by multiple rounds of dextran sodium sulfate (DSS) to induc

69 several PRRSV strains were isolated through multiple rounds of differential density gradient centrif

70 initially yielded IL-5(-) Th2, but required multiple rounds of differentiation to generate IL-5(+) T

71 ereus (CiP) heme peroxidase was subjected to multiple rounds of directed evolution in an effort to pr

72 or (variable region, Vbeta) was subjected to multiple rounds of directed evolution using yeast displa

73 Finally, a given RE can undergo multiple rounds of display exocytosis.

74 lic VZ cells, SVZa cells continue to undergo multiple rounds of division and differentiation before b

75 Thus, a fraction of cells undergo multiple rounds of division without increasing in number

76 eceptor FcgammaRIIB following activation and multiple rounds of division.

77 The schizont stage is associated with multiple rounds of DNA replication and nuclear division

78 a key cell-cycle regulator that orchestrates multiple rounds of DNA replication throughout schizogony

79 lure of the control mechanisms can result in multiple rounds of DNA replication without cell division

80 accharomyces pombe can be induced to perform multiple rounds of DNA replication without intervening m

81 ific internal eliminated sequences (IES) and multiple rounds of DNA replication.

82 deltacig2 cells are defective in undergoing multiple rounds of DNA replication.

83 TPX2-injected embryos biochemically undergo multiple rounds of DNA synthesis and mitosis, and arrest

84 T-antigen to oriP is sufficient to initiate multiple rounds of DNA synthesis from oriP during each c

85 epithelium disrupts the cell cycle, causing multiple rounds of DNA synthesis without proper cell div

86 t cells in vitro, but were unable to undergo multiple rounds of DNA synthesis, demonstrating that the

87 ing that copy-up pi proteins do not initiate multiple rounds of DNA synthesis.

88 e this document, which was developed through multiple rounds of draft circulation.

89 n some transformed cells, centrioles undergo multiple rounds of duplication (reduplication) during pr

90 centriole amplification in cells undergoing multiple rounds of duplication without preventing the fo

91 ggest that the multisubstrate dNKs underwent multiple rounds of duplications with differential retent

92 an accessory ATPase, ClpV, that facilitates multiple rounds of effector delivery.

93 opose instead that this activity can lead to multiple rounds of elicitor recognition, providing a mea

94 rnalization involving receptor recycling and multiple rounds of endocytosis.

95 ly, these abnormal cystocytes do not undergo multiple rounds of endoreplication as the nurse cells do

96 In cases when multiple rounds of enrichment are required, the software

97 Multiple rounds of enrichment with a target plasmid repr

98 false positive or negative rates necessitate multiple rounds of enrichment.

99 the peroxisome membrane, but participates in multiple rounds of entry into the peroxisome matrix and

100 This scheme allows us to perform multiple rounds of evolution (addressing approximately 1

101 cells exposed to adriamycin, leading to the multiple rounds of exchange between EPCs and mature cell

102 neurotransmission, synaptic vesicles undergo multiple rounds of exo-endocytosis, involving recycling

103 ease is further sustained by DCVs undergoing multiple rounds of exocytosis.

104 JBPs and associated transposons as involving multiple rounds of expansion with concomitant lineage so

105 eds to be an iterative process that requires multiple rounds of experimental validation together with

106 ction and then isolated clones that survived multiple rounds of exposure to the virus.

107 labor-intensive, iterative process requiring multiple rounds of extraction and polymerase chain react

108 Multiple rounds of extraction, purification, followed by

109 eveloped and circulated for the inclusion of multiple rounds of feedback from both the Working Group

110 After multiple rounds of feedback from experts on clinical pra

111 igand-binding library clones are selected by multiple rounds of fluorescence-activated cell sorting.

112 romoter and selected for high activity using multiple rounds of fluorescence-activated cell sorting.

113 Many vacuoles in the population undergo multiple rounds of fusion; methods are presented for dis

114 28 loci within genomes was generated through multiple rounds of gene duplication followed by function

115 Multiple rounds of genome duplication and extensive gene

116 Endoreplicating cells generally undergo multiple rounds of genome replication without chromosome

117 injection activated the cardiac program, and multiple rounds of GMT protein delivery significantly im

118 t respond to sudden nutrient limitation with multiple rounds of growth and division before differenti

119 By multiple rounds of growth in the mutator strain, and inc

120 In cells that underwent multiple rounds of H2O2 treatments, we identified a gene

121 Multiple rounds of heat-cool extension cycles, akin to P

122 hat Gp59 from the HLC is recycled to promote multiple rounds of helicase assembly on Gp32-ssDNA, a ca

123 for algal-gene origin in ciliates either via multiple rounds of horizontal gene transfer (HGT) from a

124 esent-day bread wheat genome is a product of multiple rounds of hybrid speciation (homoploid and poly

125 s showed that DNA loss was minimal, allowing multiple rounds of hybridization.

126 premature death of GC B cells might preclude multiple rounds of hypermutation necessary to generate a

127 far, APC-based vaccinations usually include multiple rounds of immunization.

128 ent multiplexing pipelines typically involve multiple rounds of immunofluorescence staining across mu

129 We use off-the-shelf antibodies for multiple rounds of immunolabeling and imaging of a tissu

130 osolized RBD-62, a protein developed through multiple rounds of in vitro evolution of SARS-CoV-2 RBD

131 een accomplished by DNA shuffling, involving multiple rounds of in vitro recombination and mutation o

132 Comparison of single and multiple rounds of in vitro run-off transcription sugges

133 suited for prohead binding, were obtained by multiple rounds of in vitro selection.

134 nal splicing enhancers were then selected by multiple rounds of in vitro splicing in nuclear extracts

135 IL-23 maintains the Th17 phenotype over multiple rounds of in vitro stimulation most efficiently

136 ffectors in the lung was observed only after multiple rounds of in vitro stimulation of RSV G-specifi

137 a susceptible cancer cell line (P0/TC-1) to multiple rounds of in vivo immune selection.

138 uppression of BCR-ABL1expression, even after multiple rounds of induction and reversion.

139 nity against Plasmodium takes many years and multiple rounds of infection and cure.

140 duction in sensitivity is sufficient to keep multiple rounds of infection from terminating in the pre

141 biased cell-based screening system involving multiple rounds of infection in a 96-well format.

142 T-4 T-cell line has been reported to support multiple rounds of infection of HIV-1 encoding a gp41 CT

143 The high-titer viremia development implies multiple rounds of infection that proceed in the backgro

144 transgenic mouse cells remains available for multiple rounds of infection with different ASLV vectors

145 tant viruses, we are able to select, through multiple rounds of infection, those sequences imparting

146 presumably due to the compounding effects of multiple rounds of infection.

147 and the mutant's defect was maintained over multiple rounds of infection.

148 immunological parameters can be increased by multiple rounds of infections and praziquantel-induced c

149 ms a stable complex with DNA and can promote multiple rounds of initiation by polymerase.

150 FIIIB)-DNA complexes that are stable through multiple rounds of initiation.

151 form of the protease and as such engages in multiple rounds of interaction with substrate proteins,

152 dred sixty-seven patients, most of them with multiple rounds of IVM, were recruited in areas with IVM

153 fusion and to track single vesicles through multiple rounds of kiss-and-run and reuse, without pertu

154 nized Escherichia coli cells for survival to multiple rounds of lethal ampicillin exposure.

155 However, multiple rounds of library subtraction resulted in high

156 ion of ATI mRNA with inclusion bodies allows multiple rounds of local translation and prevents premat

157 results argue against the accepted view that multiple rounds of low-rate mutagenesis and stepwise sel

158 f buffers and ionic strengths and can endure multiple rounds of lyophilization while retaining high b

159 e methyl groups after transfer to facilitate multiple rounds of lysine methylation.

160 virome of Nigerien children who had received multiple rounds of mass drug administration.

161 association of Cdt1 with ORC is required for multiple rounds of Mcm2-7 loading.

162 ATP hydrolysis by ORC is required for multiple rounds of Mcm2-7 loading.

163 In a study with multiple rounds of MDA, data collected before the third

164 the same individuals not being treated over multiple rounds of MDA, which we term systematic non-tre

165 e preparations, high-cost run sequences, and multiple rounds of measurements to determine a target (o

166 lt as transfer cultures failed to grow after multiple rounds of media transfer.

167 ent than the typical silver development, and multiple rounds of metal development were found to incre

168 , surrounded by ICAM-1, created by combining multiple rounds of microcontact printing on a single sur

169 enhancing the ability of MCAK to recycle for multiple rounds of microtubule depolymerization, and pre

170 eiotic event within the basidium followed by multiple rounds of mitosis.

171 nclusions and thereby anchor the complex for multiple rounds of mRNA translation.IMPORTANCE Poxvirus

172 s are selected in an evolutionary process of multiple rounds of mutation and selection.

173 The system provides for multiple rounds of mutation in a window up to 200 base p

174 s during the consolidation period results in multiple rounds of NMDA-receptor-dependent synaptic rein

175 zed by checkpoint proteins break and undergo multiple rounds of nonallelic recombination to form tran

176 gillus nidulans, germinating conidia undergo multiple rounds of nuclear division before forming a sep

177 gillus nidulans, germinating conidia undergo multiple rounds of nuclear division before the formation

178 he filamentous fungus, Aspergillus nidulans, multiple rounds of nuclear division occur before cytokin

179 om the nucleus to allow its participation in multiple rounds of nuclear import.

180 llized poliovirus elongation complexes after multiple rounds of nucleotide incorporation.

181 -strand polymerase acted processively during multiple rounds of Okazaki fragment synthesis, i.e. the

182 we focused, was fast, bistable and supported multiple rounds of on/off switching.

183 Multiple rounds of osmotic stress followed by recovery o

184 ntering each other many times and undergoing multiple rounds of ParM-dependent segregation in a singl

185 The RNAi cells undergo multiple rounds of partial cytokinesis and accumulate nu

186 ts where prevalence did not decrease despite multiple rounds of PC.

187 limited, sample library generation relies on multiple rounds of PCR amplification, during which the a

188 It exploits the redundancy that arises from multiple rounds of PCR amplification.

189 ipeptide synthetases (LanM enzymes) catalyze multiple rounds of peptide dehydration and thioether mac

190 ity sites hydrolyze ATP slowly, they support multiple rounds of peptide hydrolysis, indicating that A

191 raction with its centriolar receptor through multiple rounds of phosphorylation.

192 he rRNA gene promoter is necessary to direct multiple rounds of Pol I transcription initiation.

193 nal domain of UBF is important for promoting multiple rounds of Pol I transcription.

194 y of the preinitiation complex or facilitate multiple rounds of polymerase recruitment.

195 RNA molecule across Pol II genes, suggesting multiple rounds of pre-initiation complex assembly and d

196 n help determine the sequence of products in multiple rounds of processive recombination and distingu

197 ESCRT-III protein lattice, thereby allowing multiple rounds of protein sorting and vesicle formation

198 to the native state in a reaction involving multiple rounds of quantized ATP hydrolysis by GroEL.

199 ion, reducing the efficiency of repair after multiple rounds of radiation, as used in fractionated ra

200 ructures in Drosophila melanogaster requires multiple rounds of Ras signaling followed by dramatic ep

201 ad a variant of uncertain significance after multiple rounds of re-analysis.

202 retained full enzymatic activity, even after multiple rounds of recycling.

203 te transcription at high levels by promoting multiple rounds of reinitiation of transcription.

204 NA primer and preventing dissociation during multiple rounds of repeat addition.

205 se cells increased beyond 4N indicating that multiple rounds of replication had occurred without an i

206 can generate infectious viruses and undergo multiple rounds of replication in T cells.

207 prevent the spread of influenza virus during multiple rounds of replication in vitro and extend survi

208 with mutant viruses which were incapable of multiple rounds of replication in vivo failed to induce

209 following rapid serial passages in vitro and multiple rounds of replication in vivo.

210 lication origins, or by viral protein-driven multiple rounds of replication initiation at viral origi

211 n in which use of a viral mutagen would over multiple rounds of replication lead to the lethal accumu

212 ate copying chemistry favored RNA synthesis; multiple rounds of replication may have led to pools of

213 rry the memory of the silenced state through multiple rounds of replication, even when the capacity t

214 of the inserted LCR, probably as a result of multiple rounds of replication.

215 that can measure replication efficiency over multiple rounds of replication.

216 of the replicon RNA was changed to an A upon multiple rounds of replication.

217 in vitro requires PARP inhibition throughout multiple rounds of replication.

218 In contrast, during lytic growth, multiple rounds of replicative transposition amplify the

219 diagnostic rate in CLD patients and required multiple rounds of review to reduce both false positive

220 exists as a stable mRNP that may facilitate multiple rounds of ribosomal loading during translation

221 enes can be stacked to the same site through multiple rounds of RMCE.

222 Each let-7-containing complex directs multiple rounds of RNA cleavage, which explains the rema

223 on-enzymatic template copying, which renders multiple rounds of RNA replication impossible.

224 expression of Trident is required to prevent multiple rounds of S phase in the heart and the liver.

225 2 caused mammary epithelial cells to undergo multiple rounds of S phase without cell division.

226 After multiple rounds of screening 13 mutants that failed to c

227 Multiple rounds of screening were enabled by a single bu

228 , however, is an iterative process requiring multiple rounds of selection and amplification that dema

229 gans genomic DNA, we devised a procedure for multiple rounds of selection and amplification that yiel

230 CPR allows for multiple rounds of selection and enrichment to identify

231 exceptional longevity that were obtained via multiple rounds of selection from a parental strain.

232 with desired binding affinities and requires multiple rounds of selection to eliminate false-positive

233 Through multiple rounds of selection using BNL as a control, we

234 6) different clones) in Escherichia coli and multiple rounds of selection with the alkylating agent m

235 After multiple rounds of selection, candidate Sin(-) mutant vi

236 After multiple rounds of selection, the cells that adapted thr

237 was passaged in murine fibroblast cells for multiple rounds of selection.

238 y the parental sequence, and then only after multiple rounds of selection.

239 ime, we enriched faster variants of TEV over multiple rounds of selection.

240 y of the ssDNA pools that remains even after multiple rounds of selection.

241 s (approximately 10(13)) can be subjected to multiple rounds of selective pressure, amplification, an

242 Similar to the human, ferret oRGs underwent multiple rounds of self-renewing divisions but were more

243 te SIN at or upstream of cdc7, ensuring that multiple rounds of septation do not occur.

244 cell cycle arrest in late mitosis and permit multiple rounds of septation.

245 hromosomes in the same metaphase cells using multiple rounds of sequential fluorescence in situ hybri

246 multilineage differentiation potential after multiple rounds of serial bone marrow transfer over a pe

247 RssB participates in multiple rounds of sigma(S) degradation, demonstrating i

248 Using molecular dynamics simulations and multiple rounds of simulated annealing, we then relaxed

249 t yield high levels of siRNAs, indicative of multiple rounds of siRNA amplification, are disproportio

250 ome unlinking can instead be accomplished by multiple rounds of site-specific recombination.

251 itu hybridization, immunohistochemistry with multiple rounds of staining and de-staining in non-secti

252 This novel phenotype is stable over multiple rounds of stimulation in the presence of Th1-in

253 ssor cells (Ts) can be generated in vitro by multiple rounds of stimulation with allogeneic, xenogene

254 re Th17 cells, but cells that have undergone multiple rounds of stimulation, either in vivo during a

255 egulatory "gating" mechanism normally blocks multiple rounds of strand exchange and triggers product

256 ggest that CRAG degradation proceeds through multiple rounds of substrate binding to GroEL, followed

257 urther demonstrate that these EGSs engage in multiple rounds of substrate recognition while assisting

258 xb1 and varphiC31, we were able to carry out multiple rounds of successive and targeted DNA integrati

259 is designed to gauge expert opinion through multiple rounds of surveys until a consensus is reached.

260 We show that the chytrid undergoes multiple rounds of synchronous nuclear division, followe

261 Transcription entailed multiple rounds of synthesis, with transcript ratios rem

262 C. elegans relative to C. briggsae is due to multiple rounds of tandem duplication and translocation

263 ired for miRNA processing, RISC assembly, or multiple rounds of target-RNA cleavage.

264 Our approach utilizes multiple rounds of targeted imaging at different scales

265 vidual elongation complexes do not engage in multiple rounds of TCR with successive lesions.

266 e internal RNA template and in some cases by multiple rounds of template copying before product disso

267 n retain its single-stranded product through multiple rounds of template dissociation and repositioni

268 various PSCP methods on public datasets from multiple rounds of the Critical Assessment of Structure

269 Planning Estimation Model and uses data from multiple rounds of the Demographic and Health Survey, th

270 TP binding step becomes rate-limiting in the multiple rounds of the dNTP incorporation by MuLV RT, es

271 With multiple rounds of this energy-dissipative recycling, we

272 ctive synthesis of the transcript or undergo multiple rounds of transcript slipping.

273 This requires multiple rounds of transcription and thus cannot rely so

274 as a substantially higher ability to support multiple rounds of transcription at certain promoters, s

275 ses with negative supercoiling and also with multiple rounds of transcription compared with single ev

276 Experiments using single and multiple rounds of transcription indicate that these chr

277 factors SNAP(c), TBP, Brf2, and Bdp1 directs multiple rounds of transcription initiation and terminat

278 nd that Pol II-TFIIF was active in promoting multiple rounds of transcription while Pol II-Med was ne

279 re promoter is very inefficient but supports multiple rounds of transcription.

280 here was no functional 'memory' facilitating multiple rounds of transcription.

281 BP-TAF complexes, remain promoter- bound for multiple rounds of transcription.

282 learance and/or reinitiation, as measured by multiple rounds of transcription.

283 kedly different yields of RNA product during multiple rounds of transcription.

284 actor, recruits RNA polymerase (Pol) III for multiple rounds of transcription.

285 re-initiation complex that is stable through multiple rounds of transcription.

286 t not only Set1/COMPASS recruitment but also multiple rounds of transcription.

287 hexasome is retained on the template during multiple rounds of transcription.

288 does not require isolation of progenitors or multiple rounds of transfection.

289 plasmid, and up to 18 genes altogether after multiple rounds of transformation or sexual crosses.

290 er RG cells generate IP cells, which undergo multiple rounds of transit amplification in the outer su

291 her, our data suggest that mys has undergone multiple rounds of transposition since the peromyscine r

292 f patients who died from breast cancer after multiple rounds of treatment (70% to 100%, median 93%, s

293 However, multiple rounds of treatment are often required, increas

294 However, because multiple rounds of turnover were observed, we conclude t

295 aged between 9 to 23 years old responded to multiple rounds of ultimatum game proposals.

296 genotype A clinical isolate was subjected to multiple rounds of UV treatment and passaged in an optim

297 composed of hundreds of unique genes, during multiple rounds of vegetative growth when sporulation is

298 ities) Vps4 provides the energy required for multiple rounds of vesicle formation.

299 Multiple rounds of vesicle fusion in the absence of NSF

300 of the synaptic proteome that resulted from multiple rounds of whole genome duplication in this clad