ライフサイエンスコーパス: multisubunit

1 One such E3 is the gigantic, multisubunit 1.2-MDa anaphase-promoting complex/cyclosom

2 The multisubunit ACCase in the chloroplast is activated by a

3 her, this study demonstrates that SGF-2 is a multisubunit activator complex containing Awh.

4 Cohesin is a chromosome-bound, multisubunit adenosine triphosphatase complex.

5 e transport but are consistent with either a multisubunit, allosteric transporter, or a transporter i

6 Mediator is a multisubunit assemblage of proteins originally identifie

7 regation of separate polypeptide chains into multisubunit assemblies.

8 omponent of both the proteasome and a second multisubunit assembly, the INO80 complex.

9 V-ATPases (H(+) ATPases) are multisubunit, ATP-dependent proton pumps that regulate p

10 The multisubunit bacterial RNA polymerase (RNAp) enzyme, whi

11 t these models in the structurally unrelated multisubunit bacterial RNA polymerase.

12 Intrinsic termination signals for multisubunit bacterial RNA polymerases (RNAPs) encode a

13 A multisubunit, bidirectional [NiFe]-hydrogenase has been

14 w protein interaction surface that creates a multisubunit-binding site for an S-phase protein kinase

15 Ribosomes are multisubunit cellular assemblies that mediate translatio

16 RNA polymerases are key multisubunit cellular enzymes.

17 equential rounds of linkage would generate a multisubunit chain that pulls successive subunits into a

18 Proteasomes are multisubunit chambered proteases and, until recently, we

19 drial calcium uniporter (mtCU) is an ~700-kD multisubunit channel residing in the inner mitochondrial

20 r single copies of the mammalian double-ring multisubunit chaperonin TRiC/CCT in free solution using

21 Tagetitoxin (Tgt) inhibits multisubunit chloroplast, bacterial, and some eukaryotic

22 Whereas the multisubunit chromatin remodeler SWR1 is known to cataly

23 SWI/SNF is a multisubunit chromatin-remodeling complex that performs

24 Mediator is a multisubunit coactivator complex that facilitates transc

25 A proteolytic cleavage of a subunit in a multisubunit complex can create, at the same time, an N-

26 In humans, the multisubunit complex cohesin is made up of SMC1, SMC3, R

27 HAT-B is a multisubunit complex composed of the histone acetyltrans

28 nt-rich conditions, Atg1 is active only in a multisubunit complex comprising constitutive protein agg

29 compartments, and FANCI-D2 interacted with a multisubunit complex containing the virus-encoded single

30 its (CesAs) are the catalytic sites within a multisubunit complex for cellulose biosynthesis in plant

31 Cytoplasmic dynein is a large multisubunit complex involved in retrograde transport an

32 The SWI/SNF multisubunit complex modulates chromatin structure throu

33 Here we report the identification of a multisubunit complex named BORC that regulates lysosome

34 functional component of Integrator (INT), a multisubunit complex required for 3'-end processing of s

35 The proteasome is a multisubunit complex responsible for most nonlysosomal t

36 erts its effects on actin dynamics through a multisubunit complex termed Arp2/3.

37 NADPH oxidase is a multisubunit complex that assembles during phagocytosis

38 I-E CRISPR-Cas system Cascade effector is a multisubunit complex that binds CRISPR RNA (crRNA).

39 The vacuolar ATPase (V-ATPase) is a multisubunit complex that carries out ATP-driven proton

40 The eukaryotic 26S proteasome is a large multisubunit complex that degrades the majority of prote

41 s process also involves the DREAM complex, a multisubunit complex that has recently been identified a

42 Mediator is a large, multisubunit complex that is required for essentially al

43 MICOS is a conserved multisubunit complex that localizes to mitochondrial cri

44 omoting complex/cyclosome (APC/C) is a large multisubunit complex that regulates cell cycle progressi

45 the protein-protein interactions within the multisubunit complex were measured by isothermal titrati

46 It forms a multisubunit complex with TatB and binds the signal pept

47 Several proteins dedicated to this multisubunit complex, including BRG1 (also known as SMAR

48 stood, but some can act independently of the multisubunit complex.

49 4 (H3K4) methyltransferase that exists as a multisubunit complex.

50 ent viruses use different components of this multisubunit complex.

51 regulation, and yet it is unclear how these multisubunit complexes coordinate their activities to fa

52 an innovative method to investigate PPIs of multisubunit complexes effectively and to identify new m

53 istone acetyltransferases (HATs) function as multisubunit complexes in which accessory proteins regul

54 ic cells, oxidative phosphorylation involves multisubunit complexes of mixed genetic origin.

55 velopment incorporate peptides, subunits, or multisubunit complexes representing parts or all of the

56 In this review, we describe how these multisubunit complexes target and cleave DNA and RNA and

57 Kinetochores are multisubunit complexes that assemble on centromeres to b

58 The proteasomes are multisubunit complexes that catalyze the degradation of

59 SWR-C/SWR1 and INO80 are multisubunit complexes that catalyze the deposition and

60 l insights into the assembly and function of multisubunit complexes that may not be revealed by using

61 VGCCs are multisubunit complexes that play a crucial role in neuro

62 Given that RUVBL1 is part of different multisubunit complexes that play key roles in transcript

63 Proteasomes are large, multisubunit complexes that support normal cellular acti

64 s, or remodelers, which are typically large, multisubunit complexes that use an ATPase subunit to tra

65 ATP-dependent motors that often function in multisubunit complexes to regulate chromatin structure.

66 Most proteins assemble into multisubunit complexes(1).

67 conserved from yeast to humans, assemble in multisubunit complexes, and are needed to regulate gene

68 n and purification, propensity to form large multisubunit complexes, and challenges pertinent to iden

69 mTOR functions as part of either of the two multisubunit complexes, mTORC1 and mTORC2, but molecular

70 unction in leukemia occurs in the context of multisubunit complexes, which also protect the LMO2 onco

71 echanism to enforce hierarchical assembly in multisubunit complexes.

72 lution with reversible formation of ordered, multisubunit complexes.

73 ding the molecular regulation of HATs within multisubunit complexes.

74 nover of proteasomes and several other large multisubunit complexes.

75 PHB complex participates in the assembly of multisubunit complexes; namely, respiratory complex I an

76 , and the sugar-specific membrane-associated multisubunit components enzymes IIC (EIIC) and IID (EIID

77 Whether vasoconstrictors regulate the multisubunit composition of surface BK channels to stimu

78 Whether the multisubunit composition of surface channels is fixed fo

79 The multisubunit composition of the transduction complex and

80 n mammals, is specifically recognized by the multisubunit CPSF (cleavage and polyadenylation specific

81 The multisubunit cullin RING E3 ubiquitin ligases (CRLs) tar

82 s its overall architecture is reminiscent of multisubunit cullin-RING ubiquitin ligase complexes.

83 J-NAIP2-NLRC4 inflammasome is assembled into multisubunit disk-like structures through a unidirection

84 The multisubunit DNA repair and transcription factor TFIIH m

85 LMO2 is a component of multisubunit DNA-binding transcription factor complexes

86 Poxviruses encode a multisubunit DNA-dependent RNA polymerase (vRNAP) that c

87 tch 3 is a polypeptide loop conserved in all multisubunit DNA-dependent RNA polymerases (RNAPs) that

88 , including eukaryotic, membrane, toxic, and multisubunit DNA/RNA-binding proteins.

89 Here we report the identification of a multisubunit Dot1 complex (DotCom), which includes sever

90 The TO cytoskeleton is organized as a multisubunit dynamic motor, including three main ultrast

91 Cilia motility requires the assembly of multisubunit dynein arms that drive ciliary bending.

92 he architecture of the Dsc E3 ligase and the multisubunit E3 ligase gp78 in mammals.

93 (linear ubiquitin chain assembly complex), a multisubunit E3 ligase.

94 advance our organizational understanding of multisubunit E3 ligases involved in endoplasmic reticulu

95 complex or cyclosome (APC/C) is a conserved, multisubunit E3 ubiquitin (Ub) ligase that is active bot

96 One such master regulator is the large, multisubunit E3 ubiquitin ligase anaphase-promoting comp

97 A central player in the pathway is a multisubunit E3 ubiquitin ligase complex or the FA core

98 phase Promoting Complex/Cyclosome (APC/C), a multisubunit E3 ubiquitin ligase targeting cell-cycle fa

99 se-promoting complex or cyclosome (APC/C), a multisubunit E3 ubiquitin ligase, is regulated by phosph

100 ing complex/cyclosome(Cdh1) (APC/C(Cdh1)), a multisubunit E3 ubiquitin ligase.

101 Cullin-RING ligases are multisubunit E3 ubiquitin ligases that recruit substrate

102 ely 300 human cullin-RING ligases (CRLs) are multisubunit E3s in which a RING protein, either RBX1 or

103 R-Cas systems are divided into Class 1, with multisubunit effector complexes, and Class 2, with singl

104 adaptable immune system that is mediated by multisubunit effector complexes.

105 uinone oxidoreductase (complex I/NDH-1) is a multisubunit enzymatic complex.

106 active site (C-cluster) of the bifunctional multisubunit enzyme complex carbon monoxide dehydrogenas

107 aryotic vacuolar H(+)-ATPase (V-ATPase) is a multisubunit enzyme complex that acidifies subcellular o

108 ulation existing between two subunits of the multisubunit enzyme complex, GPI-N-acetylglucosaminyltra

109 t targeted, signal-dependent dissociation of multisubunit enzyme complexes is an important mechanism

110 It is a multisubunit enzyme embedded in the lipid environment of

111 (2+) into protoporphyrin IX catalyzed by the multisubunit enzyme magnesium chelatase.

112 proton-translocating ATPase (V-ATPase) is a multisubunit enzyme responsible for organelle acidificat

113 Oligosaccharyl transferase (OT) is a multisubunit enzyme that catalyzes N-linked glycosylatio

114 (NADH ubiquinone oxidoreductase) is a large multisubunit enzyme that catalyzes the first step in oxi

115 Telomerase is a multisubunit enzyme that maintains genome stability thro

116 Phosphodiesterase-6 (PDE6) is a multisubunit enzyme that plays a key role in the visual

117 ating that some basic regulation of the PDE6 multisubunit enzyme was maintained albeit by a unknown m

118 DPH oxidase (NOX), the superoxide-generating multisubunit enzyme.

119 gene expression trends was found for 65% of multisubunit enzymes and 75% of allosteric reactions.

120 Axonemal dyneins are multisubunit enzymes that must be preassembled in the cy

121 n order to operate in a coordinated fashion, multisubunit enzymes use cooperative interactions intrin

122 there is no structural information on these multisubunit enzymes.

123 h roles in assembly and nuclear transport of multisubunit eukaryotic RNA polymerases.

124 as XRN4, or in the opposite direction by the multisubunit exosome complex.

125 In vivo, a multisubunit FA core complex catalyzes this step, but it

126 and its binding partner, FAAP24, anchor the multisubunit FA core complex to chromatin after DNA dama

127 duced by uropathogenic Escherichia coli, are multisubunit fibres crucial in recognition of and adhesi

128 esentative of a widespread class of adhesive multisubunit fibres in Gram-negative bacteria.

129 rom the tumor cell surface by the ubiquitous multisubunit gamma-secretase (GS) complex, which reduces

130 The multisubunit gamma-tubulin complex (gamma-TuC) is critic

131 The multisubunit GPC glycoprotein spike complex displayed on

132 ion of three tubulin cofactors and Arl2 as a multisubunit GTP-hydrolyzing catalytic chaperone that cy

133 f eukaryotic initiation factor 2B (eIF2B), a multisubunit guanine nucleotide exchange factor.

134 tion of a DNA double-strand break (DSB) by a multisubunit helicase-nuclease machine (e.g. RecBCD, Add

135 l to the recombination pathway driven by the multisubunit helicase-nuclease machine RecBCD.

136 Together with CcmF and CcmH, CcmI forms a multisubunit heme ligation complex.

137 SAGA (Spt-Ada-Gcn5) complex, a well-studied multisubunit histone modifier, regulates gene expression

138 The multisubunit homotypic fusion and vacuole protein sortin

139 l stress response that antagonizes mTORC1, a multisubunit host kinase that controls protein synthesis

140 iated by single-subunit T7 RNA polymerase or multisubunit human RNA polymerase II in vitro and in hum

141 iated by single-subunit T7 RNA polymerase or multisubunit human RNA polymerase II in vitro and in hum

142 tations onto a model of the structure of the multisubunit IN-viral DNA complex, we found the lethal m

143 g to eIF4G, thereby reducing assembly of the multisubunit initiation factor eIF4F, viral protein prod

144 Why eukaryotes evolved a multisubunit initiator, and the roles of each component,

145 tic elements by an RNA-guided, RNA-targeting multisubunit interference complex.

146 nt-based drug design that were applicable to multisubunit ion channels.

147 rases METTL3 and METTL14 are components of a multisubunit m(6)A writer complex whose enzymatic activi

148 vacuolar H(+) ATPase (V-ATPase) is a complex multisubunit machine that regulates important cellular p

149 Structures of multisubunit macromolecular machines are primarily deter

150 any cyanobacteria use brilliantly pigmented, multisubunit macromolecular structures known as phycobil

151 hanism involving recruitment to ERSEs of the multisubunit Mediator and several histone acetyltransfer

152 Molecular Cell provide insights into how the multisubunit Mediator coactivator complex dynamically li

153 The multisubunit Mediator, comprising approximately 30 disti

154 Photosystem I (PS I) is a multisubunit membrane protein complex that functions as

155 that activate cells of the immune system are multisubunit membrane protein complexes in which ligand

156 rgy into chemical energy is catalyzed by two multisubunit membrane protein complexes, photosystem I (

157 Four multisubunit membrane proteins are involved: photosystem

158 iplasmic maltose-binding protein (MBP) and a multisubunit membrane transporter, MalFGK(2).

159 of yeast oligosaccharyl transferase (OT), a multisubunit membrane-associated enzyme complex catalyzi

160 In eukaryotes, it is catalyzed by a multisubunit membrane-associated enzyme, oligosaccharylt

161 plex I (NADH:ubiquinone oxidoreductase) is a multisubunit, membrane-bound enzyme of the respiratory c

162 of chlorophyllide a by the nitrogenase-like multisubunit metalloenzyme, chlorophyllide a oxidoreduct

163 The multisubunit mitochondrial contact site and cristae orga

164 t Swr1, brackets two independently assembled multisubunit modules.

165 reconstitution and characterization of this multisubunit monoubiquitin E3 ligase, providing key insi

166 ns that assemble into the FA core complex, a multisubunit monoubiquitin E3 ligase.

167 Cytoplasmic dynein is a large multisubunit motor protein complex and has a key role in

168 Cytoplasmic dynein is a 1.2-MDa multisubunit motor protein complex that, together with i

169 ecific protein-protein interactions within a multisubunit mRNA splicing complex.

170 The multisubunit mTORC1 complex integrates signals from grow

171 However, as a multisubunit, multispan, integral membrane protein, even

172 e the combinatorial complexity inherent in a multisubunit, multistate system.

173 damage responses through the formation of a multisubunit nuclear complex that facilitates the E3 ubi

174 Eukaryotes express three or more multisubunit nuclear RNA polymerases (Pols) referred to

175 The multisubunit nucleosome-remodeling enzyme complex SWR1,

176 Multisubunit outer dynein arm (ODA) motor complexes, pro

177 The IFT machinery is composed of motors and multisubunit particles, termed IFT-A and IFT-B, that car

178 sphatase 2A (PP2A), a ubiquitously expressed multisubunit phosphatase.

179 Photosystem II (PSII), a large multisubunit pigment-protein complex localized in the th

180 Photosystem II (PSII) is a multisubunit pigment-protein complex that uses light-ind

181 conservation of initiation mechanisms among multisubunit Pols and reveal a key function of yeast cor

182 apsid, containing scaffolding proteins and a multisubunit portal but lacking DNA, which matures into

183 we identified a role for the proteasome, the multisubunit protease that degrades proteins in the nucl

184 the abundance of the proteasome, the complex multisubunit protease that destroys proteins.

185 The proteasome, a complex multisubunit protease, plays a critical role in protein

186 Multisubunit protein assemblies offer integrated functio

187 densin is a large, evolutionarily conserved, multisubunit protein assembly composed of dimers of the

188 The v-ATPase, a multisubunit protein complex composed of cytosolic V1-se

189 Escherichia coli RNA polymerase (RNAP) is a multisubunit protein complex containing the smallest sub

190 The RNA exosome is a multisubunit protein complex involved in RNA surveillanc

191 Vacuolar H+-ATP complex (V-ATPase) is a multisubunit protein complex required for acidification

192 cle targeting and fusion require a conserved multisubunit protein complex termed the exocyst, which h

193 e and cristae organizing system (MICOS) is a multisubunit protein complex that is essential for the p

194 Cohesin is a conserved multisubunit protein complex that participates in chromo

195 terations in the function of the retromer, a multisubunit protein complex that plays a specialized ro

196 or signal-induced selective disassembly of a multisubunit protein complex to modulate activity.

197 Mediator, an evolutionary conserved large multisubunit protein complex with a central role in regu

198 ullin4A-RING E3 ubiquitin ligase (CRL4) is a multisubunit protein complex, comprising cullin4A (CUL4)

199 The multisubunit protein complex, dynactin, is an essential

200 Condensin, an evolutionarily conserved multisubunit protein complex, is essential for chromosom

201 Mediator, a large multisubunit protein complex, plays a pivotal role in ge

202 Human Scml2 is a part of a multisubunit protein complex, PRC1 (Polycomb repressive

203 A multisubunit protein complex, which is related to human

204 ers, thereby nucleating the formation of the multisubunit protein complex.

205 on of mRNA precursors is mediated by a large multisubunit protein complex.

206 Multisubunit protein complexes are ubiquitous in biology

207 The HVCCs are multisubunit protein complexes composed of a pore-formin

208 The constituents of large, multisubunit protein complexes dictate their functions i

209 iquitin ligases (CRLs) are large and diverse multisubunit protein complexes that contribute to about

210 lated through the assembly onto chromatin of multisubunit protein complexes that license DNA for a fu

211 g to fold properly or to assemble into their multisubunit protein complexes.

212 cal reactions that are uniquely performed by multisubunit protein complexes.

213 dentify substrates and accessory subunits of multisubunit protein complexes.

214 define dominant trafficking domains in other multisubunit protein complexes.

215 used to target the subunit interfaces of any multisubunit protein having a similar mechanism of actio

216 The reduced efficacy is reminiscent of multisubunit protein ion channels assembled with incorre

217 It is now believed that conserved multisubunit protein machines extract these lipids after

218 The GABA(A) receptor is a multisubunit protein that transduces the binding of a ne

219 d act within the cell to alter assembly of a multisubunit protein.

220 le and pragmatic strategy to assemble chosen multisubunit proteins into more complex structures.

221 the importance of including all subunits of multisubunit proteins to map realistic kinetically acces

222 n, and Changeux (MWC) explained allostery in multisubunit proteins with a widely applied theoretical

223 e 26S proteasome is a 2.5-MDa, ATP-dependent multisubunit proteolytic complex that processively destr

224 The vacuolar H(+)-ATPase (V-ATPase), a multisubunit proton pump, has come into focus as an attr

225 hemoglobins of gnathostomes and cyclostomes, multisubunit quaternary structures provide the basis for

226 The T cell antigen receptor (TCR) is a multisubunit receptor on the surface of T cells that is

227 ns can function as master regulators of this multisubunit repressor complex (E2F-Rb-HDAC) to reverse

228 litate KLF14 expression by antagonizing this multisubunit repressor complex in EBV-positive cells.

229 The RNA exosome is an essential multisubunit ribonuclease (RNase) that contributes to cy

230 ssRNA is channeled through its multisubunit ring-like core into the active site tunnel

231 protein complexes consisting of two stacked multisubunit rings, which open and close in an ATP-depen

232 ediate protein folding in a cavity formed by multisubunit rings.

233 Subunit D of multisubunit RNA polymerase from many species of archaea

234 by controlling the activities of essential, multisubunit RNA polymerase transcription elongation com

235 a complete transcription system, including a multisubunit RNA polymerase, stage-specific transcriptio

236 xviruses are large DNA viruses that encode a multisubunit RNA polymerase, stage-specific transcriptio

237 Eukaryotic and archaeal multisubunit RNA polymerases (Pols) are structurally rel

238 The secondary channel (SC) of multisubunit RNA polymerases (RNAPs) allows access to th

239 Evolution-related multisubunit RNA polymerases (RNAPs) carry out RNA synth

240 Transcriptional pausing by multisubunit RNA polymerases (RNAPs) is a key mechanism

241 The active site of multisubunit RNA polymerases (RNAPs) is highly conserved

242 Evolutionary related multisubunit RNA polymerases (RNAPs) transcribe the geno

243 , which forms the catalytic site in cellular multisubunit RNA polymerases (RNAPs)(5).

244 The flap domain of multisubunit RNA polymerases (RNAPs), also called the wa

245 Poxviruses use virus-encoded multisubunit RNA polymerases (vRNAPs) and RNA-processing

246 Multisubunit RNA polymerases are complex protein machine

247 Parallels in the multisubunit RNA polymerases are discussed.

248 ntified the subunits of Arabidopsis thaliana multisubunit RNA polymerases I and III (abbreviated as P

249 Multisubunit RNA polymerases IV and V (Pols IV and V) me

250 In plants, nuclear multisubunit RNA polymerases IV and V are RNA Polymerase

251 In Arabidopsis, multisubunit RNA polymerases IV and V orchestrate RNA-di

252 with his presentation entitled "Five nuclear multisubunit RNA polymerases".

253 All eukaryotes have three essential nuclear multisubunit RNA polymerases, abbreviated as Pol I, Pol

254 ants are remarkable in having two additional multisubunit RNA polymerases, Pol IV and Pol V, which sy

255 ion factors that enhance the processivity of multisubunit RNA polymerases.

256 tion may date back to the common ancestor of multisubunit RNA polymerases.

257 e thought to assemble into two non-canonical multisubunit RNAPs - a virion RNAP (vRNAP) that is injec

258 While other multisubunit RNAPs require multipartite cis-signals and/

259 action of two varphiKZ-encoded, noncanonical multisubunit RNAPs, one of which is packed within the vi

260 ents of the two largest subunits of cellular multisubunit RNAPs.

261 The V-ATPase is a multisubunit, rotary proton pump whose precise role in h

262 oup of E3 ubiquitin ligases is formed by the multisubunit SCF complex, whose core complex (Rbx1/Cul1-

263 TCR is noncovalently coupled to a conserved multisubunit signaling apparatus, the CD3 complex, that

264 The multisubunit Smc5-Smc6 holocomplex (Smc5/6) plays a crit

265 The role of the multisubunit sodium/proton antiporter (Mrp) of Methanosa

266 chemical complementation assay to discover a multisubunit stem cell coactivator complex (SCC) that is

267 cterized terms identified by NeXO, including multisubunit structures related to protein trafficking o

268 The 26 S proteasome comprises two multisubunit subcomplexes as follows: 20 S proteasome an

269 mber 4 (AFF4) is the scaffold protein of the multisubunit super-elongation complex, which plays key r

270 RNAs (crRNAs) assemble into a 405-kilodalton multisubunit surveillance complex called Cascade (CRISPR

271 erichia coli, crRNAs are incorporated into a multisubunit surveillance complex called Cascade (CRISPR

272 ipt by the Cas6 endonuclease and loaded into multisubunit surveillance/effector complexes, allowing h

273 The multisubunit SWI/SNF and RSC complexes utilize energy de

274 ype 2 behavior is not limited to cooperative multisubunit systems.

275 Inhibiting multisubunit targets with sequential actions resembles b

276 y which the exocyst, the exocytosis-specific multisubunit tethering complex, interacts with the exocy

277 ic fusion and vacuole protein-sorting (HOPS) multisubunit tethering complex, which is involved in the

278 COG, like other multisubunit tethering complexes (MTCs), is thought to f

279 7 shares structural similarity with cellular multisubunit tethering complexes (MTCs), which control v

280 ition of Rab GTPase on transport vesicles by multisubunit tethering complexes and subsequent coupling

281 erly localized vesicle fusion, including the multisubunit tethering complexes and the SNARE complexes

282 Two related multisubunit tethering complexes promote endolysosomal t

283 uctural similarity to components of cellular multisubunit tethering complexes, which control vesicula

284 mediated by SNARE proteins, Rab-GTPases, and multisubunit tethering complexes.

285 The multisubunit tethering homotypic fusion and vacuole prot

286 Multisubunit-tethering complexes (MTCs) are large (250 t

287 The multisubunit TFIID plays a direct role in transcription

288 Like the more complex multisubunit transcription systems, multiple steps may e

289 bosomes are loaded onto capped mRNAs via the multisubunit translation initiation factors eIF3 and eIF

290 Type IV secretion systems (T4SSs) are large multisubunit translocons, found in both gram-negative an

291 slationally imported into organelles through multisubunit translocons.

292 of cellulose synthase proteins in this large multisubunit transmembrane protein complex and the numbe

293 The large multisubunit transport protein particle (TRAPP) II compl

294 assembly is driven by crRNA and suggest that multisubunit type I CRISPR effectors may have evolved fr

295 phase-promoting complex/cyclosome (APC/C), a multisubunit ubiquitin E3 ligase that regulates the prog

296 coni anemia group D2 protein (FANCD2) by the multisubunit ubiquitin E3 ligase, the FA core complex, i

297 moting complex/cyclosome (APC/C) is a large, multisubunit ubiquitin ligase involved in regulation of

298 itin ligase cascade involving parkin and the multisubunit ubiquitin ligase SCF(Fbw7beta).

299 ination is carried out by the Gid complex, a multisubunit ubiquitin ligase that consists of seven dif

300 s damage caused by interstrand crosslinks, a multisubunit ubiquitin ligase that monoubiquitinates two