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1 to B. cinerea negative effects in grapes and musts.
6 For instance, paralogous signaling proteins must acquire mutations that endow them with different in
8 computational problem-this is what the brain must actually accomplish to support perception and actio
12 ause invasive disease in the vertebrate host must adapt to host efforts to cripple their viability.
13 w challenges for public-health agencies that must adapt to support a new set of expertise, which mean
18 at besides interaction, the role of disorder must also be taken into account in understanding the dif
24 covering all the concentrations expected in must and wine samples, a detection limit of 75 +/- 12 mg
29 nt cells and their immediate environment and must balance multiple functionalities, including the reg
33 es are crosscut by thousands of dykes, which must be accommodated through a combination of flank slip
36 teroatoms is one of the essential goals that must be achieved in order to control the electronic prop
37 Another key finding is that prazole prodrugs must be activated inside the cell, while their rate of a
39 uring acute liver failure; however, TGFbeta1 must be activated to bind its receptor and generate down
40 ignificant impediment to DNA replication and must be actively managed in order to preserve genetic an
42 Corrosive properties of MgCl(2) hydrates must be addressed at the operating temperatures of 500-7
43 but are rooted in structural inequities that must be addressed to adequately care for communities of
44 heless, there are still many challenges that must be addressed to enable a complete understanding of
46 sed learning, as well as open questions that must be addressed to unify our understanding cerebellar
49 that early healing after orthopaedic trauma must be allowed prior to the initiation of exercise to a
51 are well placed for analysing these data but must be applied with an understanding of the relevant bi
53 ysical connections between sister chromatids must be broken before cells can divide, and eukaryotic c
56 ated that rigorous toxicological evaluations must be carried out prior to clinical translation of nan
57 sults that the hydrolysis of NO(2) in clouds must be catalyzed by organic or inorganic species adsorb
60 f raw signal contained in fast5 files, which must be compressed to enable efficient storage and trans
62 portant part of COVID-19 response, their use must be considered alongside a careful understanding of
63 ces, the lateral homogeneity of such samples must be considered as an important prerequisite for effo
64 As a form of screening, secondary findings must be considered differently from sequencing results i
65 ely affect key study outcomes; these effects must be considered during data analysis and interpretati
66 te that the effects of ASOs on transcription must be considered for appropriate experimental and ther
67 C storage that includes soil organic C (SOC) must be considered to determine whether planting trees f
68 ht that multiple biotic and abiotic pathways must be considered to scale up globally from site- and s
69 This shows that both the ERK5 kinase and TAD must be considered when assessing the role of ERK5 and t
71 d achieve desired outcomes, persons with HIV must be consistently engaged in care and able to access
72 lyzed, the space of computational mechanisms must be constrained based on what is plausible within ne
73 New-diagnosed exfoliation glaucoma patients must be controlled and treated more strictly than primar
74 report, we suggest that the auxin signaling must be controlled harmoniously by two counteracted team
84 vation efforts, but to fulfil this role they must be effective at conserving the ecosystems and speci
85 cent vaping within 90 days, other etiologies must be eliminated, and chest imaging findings must be a
87 ing and treatment of such wastewater streams must be employed to minimize the adverse impacts on huma
88 pression decreased, implying Aire expression must be established before TSA expression can occur.
90 lly distinct contraction and relaxation that must be established in the neighboring epithelium for ap
93 ology practice, musculoskeletal radiologists must be familiar with the imaging appearance of malignan
100 l features of the world are often hidden and must be inferred by constructing internal models based o
102 ite directions along the genome, translation must be inhibited at a defined point following infection
104 ible with superoxide (O(2) (*-)) production, must be insensitive to deuteration, and yields a predict
105 ndent process suggests that activity history must be integrated to determine the dynamics of global P
107 ic laboratories and the time and effort that must be invested for intralaboratory method validation.
111 ells are sensitive to heat stress and testes must be maintained outside the body for optimal fertilit
112 9, lapses in medical care and medication use must be minimized, and public health resources should be
115 matin landscape and epigenetic barriers that must be overcome for cardiac regeneration to occur.
117 12 rhizobia) help identify the barriers that must be overcome to engineer a bacterium to deliver a hi
118 transboundary species, the global community must be prepared to invest in some regions facing greate
120 ntribution to the triple-alpha reaction rate must be present at high densities, this effect needs to
122 emories become destabilized on retrieval and must be reconsolidated into long-term memory stores to p
123 etector is susceptible to over-detection and must be refined for robust, reproducible detection in a
125 its internalization into endolysosomes, Tat must be released in order for it to activate the HIV-1 L
126 f immune responses in patients and therefore must be removed at the expense of purification yields.
128 proton transfer reactions, the product ions must be removed from the reaction cell as they are forme
131 riptional programs that define cell identity must be restarted in each cell cycle(2-5) but how this i
132 mple, when multiple stimulus-action mappings must be retained and used.SIGNIFICANCE STATEMENT Everyda
133 rmed the alternative scheme, the adh-1 locus must be retired from the PubMLST scheme if it is to be r
139 ses, large amounts of specific sphingolipids must be synthesized for specialized physiological functi
146 nt functions throughout infection and, thus, must be temporally and precisely regulated for successfu
152 solvation behavior of the solvent molecules must be understood because the electrochemical propertie
154 d risk reduction for each of these therapies must be weighed against its cost and potential adverse e
156 ong constraints on their binding sites; they must block the diffusion of the excess of twist through
157 Computational tools for Strand-seq analyses must capture the strand-specific information embedded in
158 o be sped up by a quantum computer, thus one must carefully identify areas where quantum advantage ma
159 sufficient flexibility, biological organisms must cognize beyond immediate reaction to a physically p
160 We propose that the song system motor code must compensate for these changes to achieve its acousti
162 spin labels, the structure of the nitroxides must confer reduction resistance to withstand the reduct
163 interpreting loss-of-function phenotypes and must consider both cellular and developmental context.
167 not taking PrEP; and finally, an individual must continue to attend health-care visits or discontinu
170 block of the Hessian, although these values must correctly reflect the influence of the whole enviro
173 event COVID-19 and future such pandemics, we must create the conditions that can keep population-leve
174 y the malnutrition universal screening tool (MUST), CT derived body composition as measured by skelet
175 rry out this function, the blood vasculature must deliver oxygen and nutrients and recruit circulatin
178 the structure and function of chromatin, we must determine the structures of nucleosomes containing
179 finding of a small renal mass, radiologists must determine whether it is benign or malignant, and if
181 lity," the US biomedical research enterprise must directly confront the reality of structural racism
182 the mimetic pheromone during mate search but must discriminate against the model cue to avoid orienti
183 ALI is a diagnosis of exclusion; the patient must elicit a history of recent vaping within 90 days, o
184 oach to address this conservation gap, which must enable megafaunal populations to recover to functio
185 nt and future, a successful vaccine platform must enable rapid discovery, scalable manufacturing and
187 To prevent future zoonoses, governments must establish effective legislation addressing wildlife
188 cessfully complete its life cycle, Chlamydia must evade both intracellular innate immune responses an
189 A successful mutation leading to cancer must evolve to be adaptive, enabling a cancer cell to se
190 a result, we find that DNA-bridging proteins must exert rather strong constraints on their binding si
191 smaller pixel arrays, the emissive material must exhibit wider colour gamut so that each of the vast
194 ion with offspring disease risk, a framework must first be built with insight into the expected biolo
197 asite to establish an infection in flies, it must first colonize the area between the peritrophic mat
198 odels of memory updating propose that people must first generate memory-based predictions to detect a
200 cleoid-associated proteins known to wrap DNA must form higher protein-DNA complexes to efficiently wo
202 Animals that move through complex habitats must frequently contend with obstacles in their path.
204 safe delivery to cancer cells, nucleic acids must generally be packaged into a vehicle, such as a nan
206 irst, the shape of the substrate nanocrystal must guide the crystallographic orientation of the overg
207 can successfully create these two properties must have a rank that is nearly linear in the number of
208 rm DNA as the carrier of genetic information must have co-evolved with a means to manipulate its comp
209 ral standard-of-care and long-acting groups, must have completed the 52-week comparative phase with a
211 ranscription factor network of proteins that must heterodimerize with MYC-associated factor X, or MAX
213 hieve cardiovascular health for all, the AHA must include a broader vision of health and well-being a
220 Surveillance programs for invading pathogens must initially meet challenges that include low rates of
223 es sensory information to guide behavior, we must know how stimulus representations are transformed t
226 t of complex, chronic illness management and must make difficult decisions about their own health, pa
229 y, the demands of written health information must match the reading capacities of the target audience
230 ID-19 risk estimates, the research community must meet robust methodological and communication standa
234 ic drugs, their bioaccessibility predictions must not be based only on the determination of their fre
235 outcome: first, a person who initiates PrEP must not seroconvert; second, there should be no more th
236 synthesize amino acids de novo and therefore must obtain oligopeptides from its host cell for growth.
237 HIV-1 capsid core disassembly (uncoating) must occur before integration of viral genomic DNA into
240 indicate that conformational rearrangements must occur in the N terminus of FepA during FeEnt transp
241 tigate the impact of UV-C treatment of grape must on the sensory characteristics of the resulting win
244 f MNW networks as a replacement to ITO, they must overcome their inherent stability issues while main
245 (p < 0.01), mGPS (p < 0.05), NLR (p < 0.01), MUST (p <= 0.001), Low SMD (p < 0.05), SUVmax (p <= 0.00
246 nveloped polyomavirus simian virus 40 (SV40) must penetrate the host endoplasmic reticulum (ER) membr
248 sent; and (c) mitochondrial oxidative stress must precede the insulin stimulus to cause insulin resis
249 many species enter a period of anorexia but must preserve sufficient reserves to fuel hunting and th
251 In this computerized task, the participant must rapidly decide to shoot or not shoot at White and B
252 is therefore an autoinhibitory element that must re-orient during catalysis, as supported by molecul
253 To accomplish these repair activities, APE1 must recognize and accommodate several diverse DNA subst
254 vered that influenza-generated CD4 effectors must recognize cognate Ag at a defined effector checkpoi
255 n that coastal flooding will only worsen, we must reframe this problem as one that will disproportion
256 hat SMO, and likely also other GPCR cargoes, must release their amphipathic helix 8 from the membrane
258 en hosted by public repositories, scientists must rely on inconsistent annotation to identify and int
259 ur findings emphasize that suspicion for MMP must remain high for patients who have Foster stage 3 co
267 tween sessile and motile forms in which they must sense and respond to internal and external signals
268 wn as Borreliella burgdorferi), the bacteria must sense conditions within the vertebrate and arthropo
271 ending to currently-relevant information, we must simultaneously maintain future-relevant information
272 bsence of thermal damage in the UHPH-treated musts, since 5-hydroxymethylfurfural was not detected.
275 This suggests that forest carbon finance must strike a balance between controlling conservation i
276 Policy responses to the COVID-19 outbreak must strike a balance between maintaining essential supp
278 oals, funding agencies and training programs must support a new generation of scientists and clinicia
279 ithin this enveloping membrane, the organism must take in nutrients, secrete wastes, export proteins
280 dionuclide transport from disposal boreholes must take into account processes that may accelerate deg
288 indings from present work in all probability must, therefore, provide a reference and background cont
292 ation, when the lateral root primordia (LRP) must traverse three overlying cell layers within the par
295 and genetic risk factors for celiac disease must undergo endoscopic evaluation after 1-3 years on a
296 s to achieve high vaccination coverage; some must undertake strategies to reach persons >=15 years of
297 high efficiencies, thermophotovoltaic cells must utilize the broad spectrum of a radiative thermal s
299 The initial microbial load of the settled must was 4-log CFU/mL for both yeast and moulds, and sli