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1 and Ret(9/-) (with aganglionosis induced by mycophenolate).
2 sease prophylaxis (calcineurin inhibitor and mycophenolate).
3 methylprednisolone infusions, prednisone and mycophenolate.
4 with or without a calcineurin inhibitor and mycophenolate.
5 e obtained using mTOR inhibitors compared to mycophenolate.
6 mtuzumab/tacrolimus or daclizumab/tacrolimus/mycophenolate.
7 osuppression (IS) consisted of sirolimus and mycophenolate.
10 used immunosuppressive agents tacrolimus and mycophenolate, albeit with appropriate dose adjustment.
14 unosuppression, with concomitant tacrolimus, mycophenolate and standard dose daclizumab (SB group) or
15 uction, rapid steroid taper, and maintenance mycophenolate and tacrolimus, to 2 arms using maintenanc
16 pients received calcineurin inhibitor (CNI), mycophenolate, and posttransplant cyclophosphamide for g
17 rst 3 years postoperatively were tacrolimus, mycophenolate, and steroids, and later, tacrolimus, siro
20 spectrum disorder treated with azathioprine, mycophenolate, and/or rituximab at the Mayo Clinic and t
21 verse effects associated with tacrolimus and mycophenolate are complex, and recipient risk is not det
23 methotrexate, azathioprine, leflunomide, and mycophenolate, are often used as alternatives to steroid
26 review, the totality of evidence supporting mycophenolate CCD is examined: pharmacological character
28 nistered standardized basiliximab-tacrolimus-mycophenolate-corticosteroid immunosuppressive therapy,
29 suggest a need to escalate therapy to higher mycophenolate doses, and in one fifth of cases to add a
31 the methotrexate group vs 14 (63.6%) in the mycophenolate group (difference, -30.3% [95% CI, -51.6%
32 the methotrexate group vs 42 (55.3%) in the mycophenolate group (difference, 19.1% [95% CI, 3.6% to
33 the methotrexate group vs 56 (57.1%) in the mycophenolate group (difference, 9.5% [95% CI, -5.3% to
35 in 4627 children who received tacrolimus and mycophenolate immunosuppression and did not have multior
37 , donor hematopoietic stem cells, tacrolimus/mycophenolate immunosuppression converted to sirolimus,
38 closporine was combined with azathioprine or mycophenolate in cases unresponsive to only 1 of these d
40 different mouse models of HSCR, addition of mycophenolate increased the penetrance and severity of H
41 S precursor proliferation most likely causes mycophenolate-induced migration defects and aganglionosi
44 emtuzumab (C1H) induction and tacrolimus and mycophenolate maintenance with switch to sirolimus and w
45 ansplantation (KT) includes a combination of mycophenolates (MMF/MPA) with a calcineurin inhibitor (C
48 ly for 2 days) and GVHD immunoprophylaxis of mycophenolate mofetil (1 g three times a day, days 0-28)
49 , total body irradiation, cyclosporine A and mycophenolate mofetil (12 doses), and antilymphocyte ser
50 Post grafting immunosuppression consisted of mycophenolate mofetil (28 days) and cyclosporine (35 day
53 nation therapy with IFN-beta-1a (Avonex) and mycophenolate mofetil (Cellcept) modulated the hyperphos
54 or 3.0 mg with reduced-dose cyclosporine, or mycophenolate mofetil (MMF) 3 g/day with standard-dose c
57 acrolimus (TAC) or cyclosporine A (CsA) with mycophenolate mofetil (MMF) and steroids after heart tra
58 ceiving tacrolimus (Tac) in combination with mycophenolate mofetil (MMF) and those maintained on a re
61 olimus in addition to cyclosporine (CSP) and mycophenolate mofetil (MMF) for graft-versus-host diseas
62 d with tacrolimus (Tac) and dose-intensified mycophenolate mofetil (MMF) further adjusted individuall
63 calcineurin inhibitor (CNI) withdrawal with mycophenolate mofetil (MMF) has not become routine pract
66 ebo-controlled study of daclizumab (DZB) and mycophenolate mofetil (MMF) including DZB(+)MMF(+), DZB(
67 nzyme activity and adverse effects caused by mycophenolate mofetil (MMF) inhibition may be geneticall
71 ssigned 1:1 on day 28 posttransplantation to mycophenolate mofetil (MMF) or Everolimus combined with
72 -blinded trial, was designed to test whether mycophenolate mofetil (MMF) plus corticosteroids was sup
74 st basiliximab induction with tacrolimus and mycophenolate mofetil (MMF) therapy in renal transplanta
76 udy was to assess the effects of late CNI or mycophenolate mofetil (MMF) withdrawal on ambulatory blo
80 All patients were initially treated with mycophenolate mofetil (MMF), cyclosporine A (CsA), and p
81 rolled trial comparing early CW (tacrolimus, mycophenolate mofetil (MMF), daclizumab, and corticoster
86 drug and a calcineurin inhibitor as follows: mycophenolate mofetil (MMF)/mycophenolate sodium+tacroli
87 eived tacrolimus (FK-506, 0.1 mg/kg per day)/mycophenolate mofetil (MMF, 60 mg/kg per day), and anti-
88 ip), tacrolimus (FK506; 0.1-0.5-1 mg/kg ip), mycophenolate mofetil (MMF; 60-120-300 mg/kg oral) or ve
89 ficacy and safety of a 1-year treatment with mycophenolate mofetil (MMF; target plasma mycophenolic a
90 uding sirolimus (n = 5), bortezomib (n = 3), mycophenolate mofetil (n = 2), splenectomy (n = 2), and
91 42 patients were randomly assigned to either mycophenolate mofetil (n=69) or cyclophosphamide (n=73).
95 mmy, centre-blocked design to receive either mycophenolate mofetil (target dose 1500 mg twice daily)
96 drawal at 6-month posttransplant or continue mycophenolate mofetil + standard-exposure TAC (MMF + sTA
97 on days 3 and 4 after transplantation, oral mycophenolate mofetil 15 mg/kg per dose (maximum 1 g) ev
99 idine, azaribine, pyrazofurin [PF], AVN-944, mycophenolate mofetil [MMF], and mycophenolic acid [MPA]
101 olimus/basiliximab [Tac/Bas], 139 tacrolimus/mycophenolate mofetil [Tac/MMF], and 139 tacrolimus/MMF/
103 d prolonged-release tacrolimus, basiliximab, mycophenolate mofetil and 1 bolus of intraoperative cort
106 aCD20 antibody, followed by maintenance with mycophenolate mofetil and an intensively dosed alphaCD40
107 e that conventional immunomodulators such as mycophenolate mofetil and biologics such as rituximab ar
108 QD 0.3 mg/kg per day (Arm 3; n=304) all with mycophenolate mofetil and corticosteroids (tapered) over
110 2) standard-exposure cyclosporine, both with mycophenolate mofetil and corticosteroids; 95/115 random
114 nt and graft survivals after introduction of mycophenolate mofetil and induction with basiliximab.
115 ts given CBMPs were successfully weaned from mycophenolate mofetil and maintained on tacrolimus monot
116 e active immunosuppressive substance in both mycophenolate mofetil and mycophenolate sodium, and it i
117 py with rabbit ATG, mycophenolate sodium, or mycophenolate mofetil and rapid withdrawal of steroids.
118 d with 30% to 50% reduction in doses of both mycophenolate mofetil and Tac without antiviral therapy.
119 ipeptidylpeptidase-deficient F344 rats using mycophenolate mofetil and tacrolimus for partial lymphoc
120 py with a T cell-depleting agent followed by mycophenolate mofetil and tacrolimus is presently the mo
122 ly oral methotrexate or 1 g twice daily oral mycophenolate mofetil and were monitored monthly for 6 m
123 inhibitor (CNI) dose or conversion to either mycophenolate mofetil and/or rapamycin resulted in varia
128 h enteric-coated mycophenolate sodium versus mycophenolate mofetil at month 6 among African Americans
129 lung disease, and the present preference for mycophenolate mofetil because of its better tolerability
130 ther reduced calcineurin inhibitor (CNI) and mycophenolate mofetil by 30% to 50% (n=23), or we switch
131 dults with noninfectious uveitis, the use of mycophenolate mofetil compared with methotrexate as firs
132 SRL+mycophenolate mofetil versus tacrolimus+mycophenolate mofetil de novo, and (d) conversion from C
136 dose equal to or more than 2000 mg per day (mycophenolate mofetil equivalents) was significantly hig
138 derma-related interstitial lung disease with mycophenolate mofetil for 2 years or cyclophosphamide fo
139 l effectiveness of both cyclophosphamide and mycophenolate mofetil for progressive scleroderma-relate
140 ed from baseline to 24 months by 2.19 in the mycophenolate mofetil group (95% CI 0.53-3.84) and 2.88
141 thioprine group and in 23.5% of those in the mycophenolate mofetil group (P = 0.11), and the rate of
142 ilure were 16.4% (19 of 116 patients) in the mycophenolate mofetil group and 32.4% (36 of 111) in the
143 ptopurine (OR, 0.62; 95% CI, 0.15-2.53), and mycophenolate mofetil hydrochloride (OR, 0.66; 95% CI, 0
146 olonged-release tacrolimus, basiliximab, and mycophenolate mofetil immunosuppressive regimen is effic
147 solimumab nonimprovers were downregulated in mycophenolate mofetil improvers, suggesting that immunom
148 rmine whether rituximab with azathioprine or mycophenolate mofetil improves the high-resolution compu
150 hymocyte globulin induction, tacrolimus, and mycophenolate mofetil is associated with excellent patie
151 ith interstitial lung disease (ILD), whereas mycophenolate mofetil is effective in both polymyositis
154 es immunosuppressive therapy, typically with mycophenolate mofetil or cyclophosphamide and with gluco
156 had worsened gastrointestinal symptoms with mycophenolate mofetil or EC-MPS in combination with Tac
158 antithymocyte globulin induction followed by mycophenolate mofetil plus calcineurin inhibitors (n=28,
159 uded maintenance therapy with belatacept and mycophenolate mofetil plus induction with basiliximab an
161 adults who were randomized to cyclosporin or mycophenolate mofetil plus pulse oral dexamethasone with
162 ritis confirmed with biopsy and treated with mycophenolate mofetil presented with a 2-day history of
163 uccess in transitioning to azathioprine from mycophenolate mofetil prior to pregnancy in patients wit
164 g sirolimus to the standard cyclosporine and mycophenolate mofetil prophylaxis therapy for preventing
166 he addition of sirolimus to cyclosporine and mycophenolate mofetil resulted in a lower incidence of a
168 followed by tacrolimus starting on day 5 and mycophenolate mofetil starting on day 5 at 15 mg/kg thre
175 for 2 weeks after each infusion); rapamycin+mycophenolate mofetil treatment as maintenance therapy.
177 either 25 mg oral methotrexate weekly or 1 g mycophenolate mofetil twice daily, with a corticosteroid
179 while low DNAemia rates were associated with mycophenolate mofetil use (p < 0.0001) and EBV viral cap
180 d response system, stratified by concomitant mycophenolate mofetil use and presence or absence of int
181 acrolimus elimination at 3 months versus SRL+mycophenolate mofetil versus tacrolimus+mycophenolate mo
184 standard GVHD prophylaxis group, 15 mg/kg of mycophenolate mofetil was given orally three times daily
187 , the addition of a calcineurin inhibitor or mycophenolate mofetil was predictive for maintaining a D
192 ab 1 month before transplant; tacrolimus and mycophenolate mofetil were started 1 week before surgery
194 mmunosuppression consisted of tacrolimus and mycophenolate mofetil without induction or depletional t
196 I 1.09-2.93, compared with use of tacrolimus/mycophenolate mofetil) and following a diagnosis of cuta
197 A total of 67 patients (35 methotrexate, 32 mycophenolate mofetil) contributed to the primary outcom
198 d GVHD prophylaxis regimen (cyclosporine and mycophenolate mofetil) or the triple-drug combination re
199 e 5'-monophosphate dehydrogenase inhibitors (mycophenolate mofetil) to the immunosuppressive armament
200 ive oral methotrexate, 25 mg weekly, or oral mycophenolate mofetil, 1 g twice daily, and were followe
203 preva Lupus Management Study (ALMS) trial of mycophenolate mofetil, 3) the Lupus Nephritis Assessment
204 es (95% CI: 0.6, 9.8; P = .20) the odds with mycophenolate mofetil, a difference that was not statist
205 nolic acid (MPA) is the active metabolite of mycophenolate mofetil, a drug that is widely used for im
206 nolic acid (MPA) is the active metabolite of mycophenolate mofetil, an effective immunosuppressive dr
207 plored for this disease including Rituximab, mycophenolate mofetil, and adrenocorticotropic hormone,
209 ession consisted of basiliximab, tacrolimus, mycophenolate mofetil, and corticosteroids in 80% of pat
214 ldren with SLE received cyclophosphamide and mycophenolate mofetil, and more children with JIA receiv
215 (90% CI 0.54-0.94; p=0.044) for tacrolimus, mycophenolate mofetil, and post-transplantation cyclopho
216 thotrexate, and maraviroc; 92 to tacrolimus, mycophenolate mofetil, and post-transplantation cyclopho
217 (1:1:1) by random block sizes to tacrolimus, mycophenolate mofetil, and post-transplantation cyclopho
218 and 67 (73%) grade 4 events with tacrolimus, mycophenolate mofetil, and post-transplantation cyclopho
220 ere haematological (77 [84%] for tacrolimus, mycophenolate mofetil, and post-transplantation cyclopho
221 ppressive regime consisting of cyclosporine, mycophenolate mofetil, and prednisolone were well tolera
223 te globulin, methylprednisolone, tacrolimus, mycophenolate mofetil, and prednisone were commenced.
225 se results, the combination of cyclosporine, mycophenolate mofetil, and sirolimus has become the new
228 ntithymocyte globulin induction, tacrolimus, mycophenolate mofetil, and steroid withdrawal by day 5 a
232 ttransplantation high-dose cyclophosphamide, mycophenolate mofetil, and tacrolimus or sirolimus.
235 eks, or tacrolimus QD 0.2 mg/kg per day with mycophenolate mofetil, basiliximab, and corticosteroids
236 and immunosuppression regimes (azathioprine, mycophenolate mofetil, calcineurin inhibitors, mammalian
237 ee immunosuppressive regimen, when used with mycophenolate mofetil, corticosteroids, and anti-interle
238 her a CNI-free regimen, including sirolimus, mycophenolate mofetil, corticosteroids, and anti-interle
239 corticosteroids, cyclophosphamide, dapsone, mycophenolate mofetil, plasmapheresis, colchicine, hydro
240 unosuppressive protocol included tacrolimus, mycophenolate mofetil, prednisone, and antithymocyte glo
241 pressive treatment that included tacrolimus, mycophenolate mofetil, prednisone, and, for induction, a
242 temic sclerosis treated with five therapies: mycophenolate mofetil, rituximab, abatacept, nilotinib,
244 were treated for 14 days with prednisolone, mycophenolate mofetil, tacrolimus, a combination of thes
245 ession with oral tacrolimus, prednisone, and mycophenolate mofetil, which has continued until the pre
246 deceased donor KTRs maintained on tacrolimus/mycophenolate mofetil-based regimen along with steroid.
247 sitivity, hepatitis C virus reinfection, and mycophenolate mofetil-free regimens were significant ris
248 s under antithymocyte globulin induction and mycophenolate mofetil-tacrolimus maintenance immunosuppr
265 d were discharged on a calcineurin inhibitor/mycophenolate mofetil/steroid-free immunosuppression.
267 oglobulin/interleukin 2 receptor blocker and mycophenolate mofetil/tacrolimus (Tac)/prednisone was em
270 tioning to PBSC h-HSCT with cyclosporine and mycophenolate mofetyl + PTCY (n = 32) or PTCY + ATG (n =
272 galovirus [CMV]) in KTR on sirolimus (SRL) + mycophenolate (MPA) or SRL + tacrolimus (Tac), relative
273 hs posttransplant among everolimus (EVR) and mycophenolate (MPA) treatment arms and used a time-depen
274 cubated with serial dilutions of tacrolimus, mycophenolate (MPA), sirolimus, tofacitinib, and belatac
275 ves (octyl mycophenolate, MPA-C8E; octadecyl mycophenolate, MPA-C18E; and octadecyl mycophenolamide,
277 ddition of antiproliferative agents (such as mycophenolate or azathioprine) in preventing deteriorati
278 onor transplant recipients received CNI with mycophenolate or methotrexate for GVHD prophylaxis; 1245
280 transplant-related drugs such as tacrolimus, mycophenolate, or antithymocyte globulin go on shortage.
282 eiving reduced TAC exposure, prednisone, and mycophenolate, randomized at 3 months to be converted or
285 yclosporin, tacrolimus (Tac), enteric-coated mycophenolate sodium (EC-MPS) and sirolimus (SRL) in ora
287 with prednisolone, cyclosporine A (CsA), and mycophenolate sodium (MPS) for the first 6 months after
289 was significantly higher with enteric-coated mycophenolate sodium versus mycophenolate mofetil at mon
290 itor as follows: mycophenolate mofetil (MMF)/mycophenolate sodium+tacrolimus (TAC), MMF+cyclosporine
291 substance in both mycophenolate mofetil and mycophenolate sodium, and it is widely used after organ
292 included induction therapy with rabbit ATG, mycophenolate sodium, or mycophenolate mofetil and rapid
293 a need for consensus on practical aspects of mycophenolate target concentration intervention in conte
297 raft loss at 5 years, whereas tacrolimus and mycophenolate use was associated with reduced risk (RR,
299 ate analysis showed that only the absence of mycophenolate was associated with a better vaccine respo