ライフサイエンスコーパス: myelin protein zero

1 ells and are autoreactive against peripheral myelin protein zero.

2 th disease type 1B is caused by mutations in myelin protein zero.

3 response to neuregulin1 and did not express myelin protein zero.

4 changes, we found increased transcripts for myelin protein zero, a gene that, when mutated, can caus

5 mice, but not in the mice with deficiency of myelin protein zero, a major structural protein of compa

6 heral nerves in both mice and humans targets myelin protein zero, an Ag for which expression is Aire-

7 We characterized the mpz gene, which encodes myelin protein zero and is up-regulated in oligodendrogl

8 chwann cell markers, including Pou3f1, Egr2, myelin protein zero and myelin basic protein, is reduced

9 of key proteins such as nerve growth factor, myelin protein zero, and brain derived neurotrophic fact

10 tant alleles: two for connexin 32, three for myelin protein zero, and two for peripheral myelin prote

11 Mutations in MPZ (myelin protein zero) can cause demyelinating early-onset

12 eral proteins: peripheral myelin protein 22, myelin protein zero, connexin 32, early growth response

13 Id2 was found to augment activation of Mpz (myelin protein zero) expression.

14 t cause severe disease, such as those in the myelin protein zero gene (MPZ) and the peripheral myelin

15 Mutations in the Myelin Protein Zero gene (MPZ), encoding P0, the major s

16 More than 120 mutations in the Myelin Protein Zero gene (MPZ, P0) cause various forms o

17 The Mpz (myelin protein zero) gene codes for the principal compon

18 defective Aire-mediated central tolerance to myelin protein zero initiates an autoimmune Th1 effector

19 ropathy in part because the misfolded mutant myelin protein zero is retained in the endoplasmic retic

20 mpz gene, encoding the ortholog of mammalian myelin protein zero, is expressed in oligodendrocytes of

21 st homology to myelin protein zero (MPZ) and myelin protein zero-like 2 (MPZL2, also called epithelia

22 issense mutation in the predicted Ig protein Myelin Protein Zero-Like 3 (Mpzl3).

23 We therefore named this gene Mpzl3 (myelin protein zero-like 3).

24 , transcription factor AP-1, dystroglycan 1, myelin protein zero, mitogen-activated protein kinase 3,

25 e promoters of specific myelin genes such as myelin protein zero (MPZ) and myelin basic protein (MBP)

26 hesion molecule with the highest homology to myelin protein zero (MPZ) and myelin protein zero-like 2

27 Mutations in myelin protein zero (MPZ) are generally associated with

28 dy light chain variable domain (V(L))(1) and myelin protein zero (MPZ) are representatives of the fun

29 Mutations in myelin protein zero (MPZ) cause Charcot-Marie-Tooth dise

30 Mutations in myelin protein zero (MPZ) cause the peripheral neuropath

31 nation of the peripheral nervous system, the myelin protein zero (Mpz) gene is induced to produce the

32 n in peripheral myelin, and mutations in the Myelin Protein Zero (Mpz) gene produce wide-ranging here

33 have identified five novel mutations in the myelin protein zero (MPZ) gene, encoding the major struc

34 eral neuropathies caused by mutations in the myelin protein zero (MPZ) gene.

35 Myelin protein zero (MPZ) is a member of the immunoglobu

36 Myelin protein zero (MPZ) is the major integral membrane

37 lar genetic testing showed a complex de novo myelin protein zero (MPZ) mutation consisting of a 3bp d

38 We used a minimal fragment of the myelin protein zero (Mpz) promoter (miniMpz), which was

39 he GJB1 gene under the Schwann cell-specific myelin protein zero (Mpz) promoter was generated and del

40 was expressed in transgenic mice using a rat myelin protein zero (Mpz) promoter, which is exclusively

41 ipheral nervous system (PNS) myelin protein, myelin protein zero (MPZ), cause Charcot-Marie-Tooth Dis

42 ability of these cells to induce KROX20 and myelin protein zero (MPZ), localizes NFATC4 to the nucle

43 Mutations in MPZ, the gene encoding myelin protein zero (MPZ), the major protein constituent

44 the most abundant peripheral myelin protein, Myelin protein zero (Mpz).

45 Myelin Protein Zero (MPZ/P0) is the most abundant glycop

46 ssion of myelination-associated genes (e.g., myelin protein zero; Mpz), and failed to myelinate axons

47 duplication), 11 a connexin 32 mutation, 5 a myelin protein zero mutation, 5 a peripheral myelin prot

48 ent with a CMT2 clinical phenotype had three myelin protein zero mutations (I89N+V92M+I162M).

49 y studies on the cytoplasmic domain of human myelin protein zero (P0) (hP0-cyt) suggest that H-bondin

50 ress the early determinants of their lineage myelin protein zero (P0) and/or fatty acid binding prote

51 r example, deletion of serine 63 (S63del) in myelin protein zero (P0) induces P0 accumulation in the

52 utase active mutant SOD1(G93A) driven by the myelin protein zero (P0) promoter.

53 at neuregulin-1 (NRG1) induces expression of myelin protein zero (P0).

54 Point mutations in the cytoplasmic domain of myelin protein zero (P0; the major myelin protein in the

55 and SCN4B, and other subfamily members MPZ (myelin protein zero(P0)), MPZL1, MPZL2, MPZL3, and JAML.

56 on in MPZ causing a gain of glycosylation in myelin protein zero, the main protein of peripheral nerv

57 such as periaxin, myelin basic protein, and myelin protein zero, was decreased, genes associated wit