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1 oot, which contains PPN axons, also produced myenteric activation and contractions that were comparab
2 more neurons than capsaicin, did not produce myenteric activation or contractions unless the spinal c
4 pig is associated with hyperexcitability of myenteric AH neurones, enhanced synaptic activity in the
5 o normal levels the electrical properties of myenteric AH neurones, the proportion of S neurones exhi
10 ide increased Fos-LI dose-dependently in the myenteric and submucosal neurons of the duodenum, but no
11 observed within the soma of the majority of myenteric and submucosal neurons, although faint immunor
12 n the number of Fos-immunoreactive nuclei of myenteric and submucosal neurons, following CCK injectio
15 mount preparations of adult (8-12-week old) myenteric and submucosal plexus stained with NADPH diaph
16 vo formed neuroglial structures similar to a myenteric and submucosal plexus, had functional intersti
17 Most of the CRF-IR fibers persisted in the myenteric and submucosal plexuses after 7 days in organo
19 , the nodose ganglia, and the ganglia of the myenteric and submucosal plexuses of the duodenum follow
21 d activates the enteric nervous system (ENS; myenteric and submucosal plexuses) of the gastrointestin
23 prominently localized in nerve fibers of the myenteric and submucosal plexuses, muscularis externa an
26 ivity is restricted to neurons (submucosal > myenteric) and is not seen in glia, interstitial cells o
35 ERT-immunoreactive terminal axons surrounded myenteric dopaminergic neurons and SERT knock-out increa
36 bmucosal neuron density, and increased colon myenteric fibers per neuron when compared to the wild ty
40 attenuate dorsal vagal complex (DVC) but not myenteric Fos-like immunoreactivity (Fos-LI) induced by
42 ding precursor cells that are located within myenteric ganglia and express both Nestin and p75NTR, bu
43 at ramified extensively through many rows of myenteric ganglia and formed nerve endings in discrete a
44 combined transcriptional profiling of human myenteric ganglia and mouse EN provides a rich foundatio
46 macaques showed progressive infiltration of myenteric ganglia by CD3+ T cells and IBA1+ macrophages
47 espite an abundance of inflammatory cells in myenteric ganglia during acute infection, the ENS was no
48 luo-4) used to study activity in EGCs within myenteric ganglia during CMMCs, followed by post hoc S10
50 a majority of patients in a HSCR cohort, the myenteric ganglia from the ganglionated region are also
52 well as substance P and S100beta density in myenteric ganglia of HFD mice were increased at week 8,
55 uronal cell loss because of apoptosis in the myenteric ganglia of the adult small intestine, total my
56 varicose endings (IGVEs) were identified in myenteric ganglia of the stomach and varicose simple-typ
57 3% of biotinamide-labeled extrinsic axons in myenteric ganglia were labeled by antisera to one of the
59 ied rostrally or caudally along many rows of myenteric ganglia with little circumferential displaceme
61 ssued specialized polymorphic collaterals to myenteric ganglia, and a subset (41%) of antral longitud
72 d complex arbors of varicose neurites within myenteric ganglia/primary plexus and, concomitantly, lon
75 image analysis revealed that the severity of myenteric ganglionitis increased with time after SIV inf
78 Internalization of NK1R was not observed in myenteric ICC or smooth muscle cells in response to nerv
79 incident in subsets of neurons (submucosal > myenteric) in guinea pig and mouse intestines in situ an
80 The high-fat diet induces changes in the myenteric innervation of the small intestine, intestinal
82 rojections of circular muscle motor neurons, myenteric interneurons, and putative sensory neurons.
84 of myenteric neurons, as well as in numerous myenteric internodal fibers; immunoreactivity was rarely
86 P(+/-));Foxf2(-/-) mice had expansion of the myenteric nerve plexus and increased proliferation of sm
87 ear inclusions), loss of nerve fibers in the myenteric nerve plexus, and delayed gastrointestinal tra
89 of a high-fat diet (HFD) is associated with myenteric neurodegeneration, which in turn is associated
91 Here we have developed a Swiss-Webster mouse myenteric neuron culture and examined their electrophysi
92 Het)R3(Het)) mutant mice had a reduced colon myenteric neuron density, reduced colon myenteric neuron
95 labeling with antibody markers that identify myenteric neuron subtypes to determine when neuron subty
96 ed a computational model of a Dogiel type II myenteric neuron that successfully reproduces all experi
97 olon myenteric neuron density, reduced colon myenteric neuron to glia ratio, reduced colon submucosal
98 induced diabetic mice, there was evidence of myenteric neuronal apoptosis and reduced Akt phosphoryla
99 Deletion of TPH2, but not TPH1, decreased myenteric neuronal density and proportions of dopaminerg
100 el to compare dorsal vagal complex (DVC) and myenteric neuronal Fos-Like immunoreactivity (Fos-LI), i
102 usively with vagal-afferent endings and some myenteric neurones in mouse and human stomach, respectiv
103 The electrical and synaptic properties of myenteric neurones in normal and inflamed guinea-pig dis
109 eous intracellular recordings were made from myenteric neurons and circular muscle (CM) cells in isol
110 monstrate the feasibility of isolating mouse myenteric neurons and establish sodium channel inhibitio
111 We evaluated SSTR2A trafficking in murine myenteric neurons and neuroendocrine AtT-20 cells by mic
112 ysiologic, and pharmacologic techniques, the myenteric neurons and neurotransmitters involved in the
116 oxypyruvate altered excitatory properties of myenteric neurons and reduced islet insulin content but
117 ocal microscopy provides detailed imaging of myenteric neurons and smooth muscle cells in the muscula
119 nvestigated communication between ExPANs and myenteric neurons and the circuits by which ExPANs modul
120 F(2) activation inhibits CRF(1) signaling in myenteric neurons and the stress-induced colonic motor r
121 vestigate the morpho-quantitative aspects of myenteric neurons and the wall of the small intestine in
122 is an autoimmune disease in which esophageal myenteric neurons are attacked in a cell-mediated and an
123 has been demonstrated that subpopulations of myenteric neurons are differentially susceptible to the
126 citatory postsynaptic potentials (fEPSPs) in myenteric neurons but the subunit composition of enteric
127 tion revealed that subsets of submucosal and myenteric neurons contained mRNA encoding D2 or D3.
128 d GLP2 elicit neuroprotective effects on rat myenteric neurons cultured with or without mast cells.
129 so appeared normal in size, but NO-producing myenteric neurons developed very large nuclei as a resul
130 r GCaMP, we visualized levels of activity in myenteric neurons during smooth muscle contractions indu
134 The neuronal tissue constituted of isolated myenteric neurons from four to 12 days old Wistar rats,
135 re, we used in situ patch-clamp recording of myenteric neurons from mice to define functionally the N
136 GLP1, GLP2 and VIP were added to cultured myenteric neurons from rat small intestine or to co-cult
138 lia cells (EGCs) form a dense network around myenteric neurons in a ganglia and are likely to have no
139 to determine whether 1) different classes of myenteric neurons in the guinea pig ileum contain muOR i
140 ere made from circular muscle (CM) cells and myenteric neurons in the isolated guinea pig distal colo
143 cetylcholine neurons make up the majority of myenteric neurons in the stomach (70%), they are a minor
149 os-LI was then quantified in the DVC and the myenteric neurons of the duodenum and jejunum using a di
150 response to CCK due to increased numbers of myenteric neurons or more intestinal CCK(1) receptors th
151 tonin gene-related peptide (CGRP)-expressing myenteric neurons produce MET, the receptor for hepatocy
152 el Type II/AH sensory neurons and most other myenteric neurons responded to oral elongation with redu
153 analysis revealed that approximately 56% of myenteric neurons stained with neuronal nitric oxide syn
156 te-mapping revealed a small subpopulation of myenteric neurons that appears to express NOS1 only tran
157 essed by neurochemically distinct classes of myenteric neurons that are likely to differ functionally
158 polysaccharide lead to apoptosis in cultured myenteric neurons that express Toll-like receptor 4 (TLR
159 s significant coexpression of NOS and VIP in myenteric neurons that is more prominent in the proximal
160 d of prolonged increases in activity in many myenteric neurons that was correlated to Ca(2+) transien
161 al development of specific nAChR subtypes in myenteric neurons using Wnt1-Cre;R26R-GCaMP3 mice, where
169 t proportions in the small intestine (25% of myenteric neurons were YFP+ at P0 compared to 62% in adu
170 undergoes ligand-induced internalization in myenteric neurons, and (2) the effect of long-term incre
171 ronal cell bodies, to quantify the number of myenteric neurons, and a reverse transcriptase chain pol
172 ndrites, soma, and axons in a small group of myenteric neurons, as well as in numerous myenteric inte
173 resses colon motility by acting on intrinsic myenteric neurons, but the extent of sympathetic-induced
174 was expressed in only a small population of myenteric neurons, but was abundantly expressed in the s
175 ic mice had loss of NADPH diaphorase-stained myenteric neurons, delayed gastric emptying, and increas
176 tivity was found only in approximately 1% of myenteric neurons, extensive OT-immunoreactive varicosit
178 nal subpopulations, particularly cholinergic myenteric neurons, may be more vulnerable than others to
181 DOR localizes specifically to submucosal and myenteric neurons, which might account for the ability o
182 red in all enteric glia and most small bowel myenteric neurons, yet phenotypic effects of Rb1 loss we
200 pression of the hTDP-43 transgene in colonic myenteric plexes resulted in progressive neurodegenerati
201 reactive oxygen species (ROS) in the jejunal myenteric plexi and phosphorylation (p) of mitogen-activ
202 of neurons projected predominantly to either myenteric plexus ( approximately 13%) or smooth muscle (
203 ely 100% of an arbor's varicose branches) to myenteric plexus ( approximately 2%) or smooth muscle (
206 ctivation of the colonic longitudinal muscle myenteric plexus (LMMP) neurons and localization of CRF(
209 There are considerable differences in the myenteric plexus along different segments of the monkey
212 large, intensely immunofluorescent axons in myenteric plexus and circular muscle, and thinner varico
213 onged satiety action than CCK-8; and (3) the myenteric plexus and DVC may play roles in these differe
217 ing neural network, exemplified by lack of a myenteric plexus and extensive overgrowth of fibers.
218 nes in the same plexus, from neurones in the myenteric plexus and from sympathetic postganglionic neu
219 nd all layers of the retina) and peripheral (myenteric plexus and innervating nerves) nervous system
221 ther, these data extend our understanding of myenteric plexus architecture in maturing zebrafish, the
223 sensitive, whereas those located within the myenteric plexus are also thought to respond to changes
225 dense neuronal networks at the level of the myenteric plexus by embryonic week (EW) 12, with express
229 The proportions of CRF-IR cell bodies in the myenteric plexus increased progressively from the stomac
230 By late larval stages, complexity of the myenteric plexus increases such that a layer of axons is
231 e that synaptic facilitation in the inflamed myenteric plexus involves a presynaptic increase in PKA
232 was expressed by enteric glial cells in the myenteric plexus layer, and cultured primary enteric gli
233 (fl/fl); Wnt1Cre+) caused a dramatic loss of myenteric plexus MET-IR neurites and 1-1'-dioctodecyl-3,
234 de synthase (NOS)- and calretinin-containing myenteric plexus neurons and non-cholinergic secretomoto
237 nin gene-related peptide-immunoreactive (IR) myenteric plexus neurons thought to be intrinsic primary
239 ndritic surfaces of neurochemically distinct myenteric plexus neurons, while being on axonal compartm
241 mistry indicated that LAMB4 localizes to the myenteric plexus of colonic tissue and patients harborin
242 opulation of mechanosensory S-neurons in the myenteric plexus of the distal colon which appear to be
247 vity was confined to enteric glia within the myenteric plexus of the mouse colon; the Cx43 inhibitors
253 CRF1 receptor was distributed widely in the myenteric plexus of the stomach and small and large inte
255 t contribute to synaptic facilitation in the myenteric plexus of the trinitrobenzene sulphonic acid-i
259 ssed survival by counting various genotypes, myenteric plexus presence by acetylcholinesterase staini
260 reatment of opioid naive longitudinal muscle myenteric plexus tissue attenuates PLCbeta3 phosphorylat
261 lation in the guinea pig longitudinal muscle myenteric plexus tissue revealed substantial alterations
262 smural electrical stimuli confirmed that the myenteric plexus was always present and intact in these
263 not express opioids; opioid synthesis in the myenteric plexus was not altered on induction of inflamm
265 that the connectivity between the LM and the myenteric plexus was required for mechanotransduction.
266 removed from progressively longer lengths of myenteric plexus, a graded reduction in the correlation
267 in the postnatal rat gut are located in the myenteric plexus, and shows that these cells can be expa
268 riginates in pacemaker cells surrounding the myenteric plexus, called interstitial cells of Cajal (IC
269 neurones, enhanced synaptic activity in the myenteric plexus, increased serotonin (5-HT) availabilit
270 ooth muscle, while simultaneously contacting myenteric plexus, is consistent with the view that these
271 the enteric nervous system, specifically the myenteric plexus, of the rhesus monkey (Macaca mulatta)
272 e majority of CM was sharp dissected off the myenteric plexus, ongoing neural activity was absent, or
274 When the LM was sharp dissected off the myenteric plexus, the synchronized discharge of ascendin
275 r Hu was 100% in the P3 and 71% in the adult myenteric plexus, when submucosal neurons were also OTR-
276 ration of a robust expression of DPPX in the myenteric plexus, which strongly reacted with patients'
291 mically in neuronal perikarya (submucosal >> myenteric plexus; small intestine > stomach or colon).
292 n, both slow (slow waves, 2-8/min) and fast (myenteric potential oscillations [MPOs]; 16-20/min) elec
294 terstitial cells of Cajal distributed in the myenteric region (ICC-MY) and fibroblast-like cells (FLC
295 neurons, interstitial cells of Cajal in the myenteric region (ICC-MY) and smooth muscle cells during
297 citatory postsynaptic potentials (fEPSPs) in myenteric S neurons were evaluated, and the density of s
298 ly identified a population of mechanosensory myenteric S-interneurons in the distal colon of guinea-p
299 In contrast, when recordings were made from myenteric S-neurons, two distinct electrical patterns of
300 canine colon were pinned with submucosal or myenteric surface uppermost or cut in cross section.