ライフサイエンスコーパス: myopia

1 depression, hyperlipidemia, astigmatism, and myopia.

2 ted the association between heterophoria and myopia.

3 of the ILM were exclusively present in high myopia.

4 nopathy affecting Caucasian young women with myopia.

5 decades and to analyze the risk factors for myopia.

6 ic with AL > 25 mm, to analyze the effect of myopia.

7 hylation for early-onset but not later-onset myopia.

8 antially greater than the cost of correcting myopia.

9 to identify school children at high risk of myopia.

10 may increase the risk of children's incident myopia.

11 nce (<0.5, 0.5-1.9, >=2.0 h/d), and incident myopia.

12 each level of VI resulting from uncorrected myopia.

13 nths post-op after LASEK with MMC to correct myopia.

14 al, 1.03-1.68) had a higher risk of incident myopia.

15 nd environment play a role in development of myopia.

16 sc ratio, intraocular pressure, glaucoma and myopia.

17 ntractures, mild skeletal dysplasia and high myopia.

18 redients which might have induced the sudden myopia.

19 ence of any degenerative lesion secondary to myopia.

20 isian ICL) implantation for moderate to high myopia.

21 ar features of the choroid in eyes with high myopia.

22 ic origin, positive family history, and high myopia.

23 commonly occurred in young individuals with myopia.

24 ia M2 microkeratome (MK) in mild to moderate myopia.

25 e retina-to-sclera signaling cascade causing myopia.

26 version of the Meta-Analysis for Pathologic Myopia.

27 39 loci associated with refractive error and myopia.

28 hreatening complication associated with high myopia.

29 work and may increase the risk of developing myopia.

30 scan reliability in patients with high axial myopia.

31 or who are glaucoma suspects with high axial myopia.

32 yes with and without non-pathological, axial myopia.

33 nd thus to inhibit eye growth in progressive myopia.

34 < 0.05) with faster AL elongation: parental myopia, 1 or more books read per week, time spent readin

35 D 4.49]); rod dominated dystrophies (OR high myopia 10.1, P < .0001; OR high hyperopia 9.7, P = .001;

36 lowed by cone-dominated dystrophies (OR high myopia 19.5, P < .0001; OR high hyperopia 10.7, P = .033

37 epithelium (RPE)-related dystrophies (OR low myopia 2.7; P = .001; OR high hyperopia 5.8; P = .025; S

38 d congenital ptosis requiring surgery, 4 had myopia, 2 had retinal detachment, and 2 showed skeletal

39 associated with the highest risk of SE high myopia 239.7; odds ratio (OR) mild hyperopia 263.2, both

40 2050 there will be 4758 million people with myopia (49.8% of the world population; 3620-6056 million

41 A 20-year-old woman with bilateral high myopia (-6D) and a documented normal prior retinal exami

42 The study group comprised 114 persons with myopia (81 girls and 33 boys), while the control group c

43 .4%-55.7%]) and 938 million people with high myopia (9.8% of the world population; 479-2104 million [

44 In eyes with high myopia, after adjusting for age, choroidal vascular and

45 A total of 1523 Chinese-American adults with myopia, aged 50 years and older, residing in the city of

46 is revealed that Down syndrome, astigmatism, myopia, allergic rhinitis, and asthma were positively as

47 The prevalence of high myopia also increased from 1.39% (95% CI, 0.43%-2.35%) t

48 Myopia, also known as short-sightedness or near-sightedn

49 The prevalence of myopia among all age groups increased steadily.

50 The prevalence of myopia among schoolchildren increased rapidly from 1983

51 f this study was to assess the prevalence of myopia among secondary school students in Welkite town,

52 cataract, resulting in 371 participants with myopia and 2797 without.

53 The third eye had a history of high myopia and a scleral buckle procedure for retinal detach

54 ornea and sclera in chickens developing high myopia and astigmatism induced by form deprivation.

55 on lenticule extraction for the treatment of myopia and astigmatism was safe and effective, and the r

56 Myopia and astigmatism, two common refractive errors fre

57 raocular lenses (pIOLs) for the treatment of myopia and astigmatism.

58 ial needs children who have moderate to high myopia and difficulties wearing glasses or contact lense

59 s with ONS + FD developed -8.9 D of relative myopia and elongated by 135 mum more than in their untre

60 nalysis of the prevalence of myopia and high myopia and estimated temporal trends from 2000 to 2050 u

61 o shared aetiologies with macular condition, myopia and glaucoma.

62 Myopia and high astigmatism (>2.5 diopter) were caused b

63 CASE PRESENTATION: Two patients with myopia and high corneal astigmatism underwent cataract o

64 vices was associated significantly with both myopia and high myopia (OR, 2.43 and 2.31).

65 eview and meta-analysis of the prevalence of myopia and high myopia and estimated temporal trends fro

66 1 years of age showed markedly lower ORs for myopia and high myopia relative to Israeli-born controls

67 For this study population, the prevalence of myopia and high myopia was 42.0 and 2.0%, respectively,

68 Myopia and high myopia were defined based on right eye r

69 gth difference (ALD) (minus and plus denotes myopia and hypermetropia, respectively).

70 etween refractive error and the risk of AMD, myopia and hyperopia only minimally influence the causal

71 cted cell type and causal gene; and risks of myopia and hyperopia were evaluated using logistic regre

72 urgery was performed for lower magnitudes of myopia and hyperopia.

73 3.10]) coincided with the highest degree of myopia and in CABP4 (SE 4.81 D [SD 0.35]) with the highe

74 ether there is a genetic correlation between myopia and intelligence in over 1,500 subjects (aged 14-

75 bute significantly to the covariance between myopia and intelligence.

76 th -0.75 D to -5.00 D of spherical component myopia and less than 1.00 D astigmatism were enrolled be

77 ects and among participants with more severe myopia and longer axial length (P < .001).

78 We estimated the number of people with myopia and MMD corresponding to critical visual acuity t

79 (PIOL) implantation has been used to correct myopia and myopic astigmatism, although corneal decompen

80 VI) and blindness as a result of uncorrected myopia and myopic macular degeneration (MMD) in 2015.

81 e in the development and progression of high myopia and myopic retinopathy.

82 tion are also involved in the development of myopia and refractive error.

83 No independent associations between myopia and serum vitamin D3 concentrations nor variants

84 grade level, ethnicity, parental history of myopia and severity.

85 emonstrated an increase in the prevalence of myopia and the possible associations of urbanization- an

86 $49 billion-US$697 billion) from uncorrected myopia and US$6 billion (95% CI, US$2 billion-US$17 bill

87 udyPopulation: Twenty-six patients with high myopia and/or myopic astigmatism received randomized tre

88 ted with ocular anterior segment dysgenesis, myopia, and ectopia lentis.

89 of 13, 70%) of patients had moderate-to-high myopia, and none were using protective eyewear when they

90 or photophobia, reduced visual acuity, high myopia, and nystagmus.

91 skeletal and eye abnormalities (ie, ptosis, myopia, and retina detachment).

92 s of concurrent macular conditions including myopia, and the measurement floor of macular structural

93 tinal pigment epithelium (RPE) humps in high myopia, and to describe the distinctive features from pa

94 Patients with myopia are at increased risk for the development of glau

95 People with myopia are less likely to have adequate optical correcti

96 urrent pharmacological treatment options for myopia are limited to atropine and 7-methylxanthine, whi

97 Severe forms of myopia (pathologic myopia) are associated with a risk of other associated o

98 Refractive errors, in particular myopia, are a leading cause of morbidity and disability

99 Refractive errors, in particular myopia, are common in IRD.

100 ciated with myopia is critical to addressing myopia as an increasingly prevalent public health proble

101 at 11 years of age did not predict incident myopia at 16 years of age (p = 0.11).

102 ongation and with increased risk of incident myopia at age 16 years.

103 sex-specific, reduction in the prevalence of myopia at age 7 if the maternal grandmother had smoked i

104 en (ALSPAC), we found that the prevalence of myopia at age 7 was lower if the paternal grandmother ha

105 opia at baseline, and 27.7% of those without myopia at baseline developed incident myopia between 201

106 Overall, 26.8% of children had myopia at baseline, and 27.7% of those without myopia at

107 The discriminative accuracy for incident myopia based on these risk factors was 0.78.

108 al vascularity was greater in eyes with high myopia (beta = 0.032, P < .001).

109 ithout myopia at baseline developed incident myopia between 2010 and 2013.

110 g progression of myopia is critical, as high myopia can be complicated by a number of vision-compromi

111 rment will occur if uncorrected, whilst high myopia causes sight-threatening complications.

112 de DNA methylation analysis in a unique high-myopia cohort, showing extensive and discrete methylatio

113 Myopia, commonly referred to as nearsightedness, is one

114 diagnosed to have refractive error (n = 92), myopia constituted 83/92 (90.2%) of the students indicat

115 reported the efficacy of orthokeratology for myopia control.

116 the belief that modifiable risk factors for myopia could be targets for future public health actions

117 Spectacle correction and myopia data were combined to estimate the number of peop

118 the probability of at least one eye showing myopia (defined as < 0 D) and frequency of refined carbo

119 en (mean age 21.59 +/- 1.15 years) with high myopia (defined as -6.0 diopter [D] or worse, mean spher

120 e AL elongation was 0.21+/-0.009 mm/year and myopia developed in 223 of 2136 children (10.4%), leadin

121 on was a predictive factor for the amount of myopia developed only when the interruption was not effe

122 ivities showed significantly lower risks for myopia developing (<60 minutes: odds ratio [OR], 0.48 an

123 mong several subpopulations and the risk for myopia developing.

124 studies of the signaling pathways underlying myopia development and discuss the potential of systems

125 Immigration studies can shed light on myopia development and reveal high-risk populations.

126 hotoreceptor may serve as critical sites for myopia development.

127 After myopia develops, interruption is less effective.

128 rs of age predicted axial eye elongation and myopia during adolescence.

129 Myopia, emmetropia, and hyperopia were defined as a sphe

130 tamin D single-nucleotide polymorphisms, and myopia estimated from logistic regression.

131 s significantly increased the probability of myopia for girls (odds ratio [OR] = 1.07; 95% confidence

132 ot predict axial eye elongation and incident myopia from age 11 to 16 years.

133 us before compensation occurs prevents axial myopia from developing.

134 ater preoperative MRSE, greater preoperative myopia, greater preoperative astigmatism, and the occurr

135 tely selected patients within this very high myopia group can be included as LASIK candidates.

136 The prevalence of myopia has increased rapidly worldwide over the past few

137 Participants underwent LASIK surgery for myopia, hyperopia, and/or astigmatism.

138 if they met specific refractive criteria for myopia, hyperopia, astigmatism, or anisometropia.

139 ies of patients undergoing LASIK surgery for myopia, hyperopia, or astigmatism.

140 Importance: Myopia (ie, nearsightedness) is becoming the most common

141 pulation, hyperopia was found in 61% (4018), myopia in 20% (1336), and astigmatism in 93% (6122) of c

142 ith each level and type of VI resulting from myopia in 2015 in United States dollars (US$).

143 Evaluate risk factors for paediatric myopia in a contemporary French cohort taking into accou

144 ed whether local mechanisms also underlie FD myopia in a mammalian model.

145 nducted to detect amblyopia risk factors and myopia in a rural district of Northwestern Turkey by usi

146 86/264 (32.6%) children investigated showed myopia in at least one eye.

147 e prevalence and associated risk factors for myopia in elementary and junior high school students in

148 late during the development of lens-induced myopia in marmosets.

149 phthalmology (AAO) created the Task Force on Myopia in recognition of the substantial global increase

150 This study provided epidemiological data on myopia in rural school students in Chia-Yi, Taiwan, and

151 Attention to the correction of myopia in secondary schools students of Welkite town usi

152 between near visual activities and incident myopia in Taiwanese children 7 to 12 years old over a 4-

153 to evaluate the changes in the prevalence of myopia in Taiwanese schoolchildren over the past few dec

154 A sibling pair had unilateral high myopia in their right eyes and near emmetropia in their

155 ghest quartile of AL-to-CR ratio; incidental myopia in this group was 24% (124/513).

156 mals, including humans, consistently exhibit myopia in two different contexts: foraging, in which the

157 The prevalence of myopia increased 1.284-fold over 24 years from 20.4% amo

158 to 49, p = 0.0085) and the odds for incident myopia increased with 1.57 (95%CI 1.18 to 2.09, p = 0.00

159 tigating the efficacy and safety of multiple myopia interventions vs control conditions, were conside

160 ant resource for developing and testing anti-myopia interventions.

161 formed by adding gender, age, and pathologic myopia into the model.

162 Myopia is a common visual disorder with increasing preva

163 he Academy's Board of Trustees believes that myopia is a high-priority cause of visual impairment, wa

164 the inverse correlation due to the fact that myopia is a negative refractive error.

165 Myopia is associated with higher intelligence.

166 Axial myopia is associated with increased fibrous vitreous liq

167 ts that choroidal thinning in eyes with high myopia is associated with the reduction in both its stro

168 Myopia is becoming increasingly common globally and is a

169 Myopia is caused by both environmental and genetic risk

170 Evidence regarding the role of near work in myopia is conflicting.

171 ng the economic burden of VI associated with myopia is critical to addressing myopia as an increasing

172 Halting progression of myopia is critical, as high myopia can be complicated by

173 The prevalence of myopia is high in our study.

174 mong various ethnic groups, the incidence of myopia is increasing in all populations across globe.

175 Myopia is induced when a growing eye wears a diffuser th

176 Myopia is not associated with DR progression risk.

177 VI and blindness resulting from uncorrected myopia is substantially greater than the cost of correct

178 Myopia is the most common eye disorder in the world whic

179 Refractive error, especially myopia, is the most common eye disorder in the world and

180 Very high myopia LASIK between - 10.00 to - 13.50 D is safe and re

181 Development of myopia, lens thickening, choroidal effusion and retinal

182 predictive value of the prediction score for myopia (<=-0.5 diopter) was estimated using receiver ope

183 equivalence of <=-0.25 diopter [D]) and high myopia (<=-6.0 D) was assessed.

184 had myopia while 33 (5.3%) of 623 males had myopia making females relative risk to be 1.5 times that

185 A range of myopia management and control strategies are available t

186 0/180 Snellen]), childhood-onset nyctalopia, myopia (mean [SD] refractive error, -6.71 [-4.22]), and

187 E more than -6.00 diopters (D), preoperative myopia more than 6.00 D, preoperative astigmatism more t

188 ttracting significant scientific interest is myopia, mostly owing to the recent rise in its prevalenc

189 ) increased by 243 (202) mum in eyes without myopia (n = 630) at baseline compared with 454 (549) mum

190 ine compared with 454 (549) mum in eyes with myopia (n = 84) at baseline, p < 0.0001.

191 Myopia (near sightedness) is the most common vision diso

192 loci also exhibited pleiotropic effects with myopia, neurodegenerative diseases (e.g. Parkinson's dis

193 ng loss and both siblings had symmetric high myopia, normal stature, and ptosis.

194 n among immigration, age at immigration, and myopia occurrence during adolescence.

195 Myopia odds ratios (ORs) were calculated according to im

196 each country, standardized to definitions of myopia of -0.50 diopter (D) or less and of high myopia o

197 pia of -0.50 diopter (D) or less and of high myopia of -5.00 D or less, projected to the year 2010, t

198 As regard the influence of myopia on OCT parameters and RGC count, we performed Pea

199 derstanding the factors involved in delaying myopia onset and slowing its progression will be key to

200 ears (<= + 0.19D) signalled risk for earlier myopia onset by 10-years in comparison to baseline SER o

201 7 eyes of 289 patients receiving the Artisan Myopia or Artisan Toric (Ophtec B.V., Groningen, The Net

202 ands) iris-fixated pIOL for the treatment of myopia or astigmatism at the University Eye Clinic Maast

203 ds, genetic correlations between RD and high myopia or cataract operation were, respectively, 0.46 (S

204 A total of 200 eyes of 100 patients with myopia or compound myopic astigmatism undergoing bilater

205 Refractive error (myopia or hyperopia) was significantly associated with V

206 Patients with amblyopia, high myopia or hyperopia, coexisting retinal disease, or prio

207 opia arriving after 11 years of age showed a myopia OR of 0.65 (95% confidence interval [CI], 0.63-0.

208 ge myopic shifts that often resulted in high myopia or severe anisometropia later in childhood.

209 r than 5 years of age showed a 2-fold higher myopia OR than those migrating after 11 years of age.

210 trations was associated with a reduced OR of myopia (OR, 0.57; 95% CI, 0.46-0.72).

211 le of years of education had twice the OR of myopia (OR, 2.08; 95% CI, 1.41-3.06).

212 ated significantly with both myopia and high myopia (OR, 2.43 and 2.31).

213 with asthma, allergic rhinitis, astigmatism, myopia, or Down syndrome had higher odds ratio of KC.

214 Myopia, or near-sightedness, is our most common eye cond

215 Next, myopia ORs were calculated according to age at immigrati

216 11 years of age, who also showed lower high-myopia ORs.

217 were collected, including family history of myopia, outdoor time, reading time, screen time, physica

218 Israel recruitment center, the prevalence of myopia over time was estimated, and a polynomial regress

219 a description of the change in prevalence of myopia over time.

220 as factors associated with the prevalence of myopia over time.

221 books read per week (P < 0.01) and parental myopia (P < 0.01).

222 r age, female sex, nonwhite ethnicities, and myopia (P <= .013).

223 sed UVB exposure was associated with reduced myopia, particularly in adolescence and young adulthood.

224 Severe forms of myopia (pathologic myopia) are associated with a risk of

225 other corneal refractive surgeries on adult myopia patients and evaluated corneal biomechanics were

226 Recognizing the LRPAP1-related high myopia phenotype is important, and early childhood exami

227 of heritability and improve the accuracy of myopia prediction (area under the curve (AUC) = 0.75).

228 ition of the substantial global increases in myopia prevalence and its associated complications.

229 cording to age at immigration, a decrease in myopia prevalence and ORs with increasing age at migrati

230 n 223 of 2136 children (10.4%), leading to a myopia prevalence at 9 years of age of 12.0%.

231 This increase in myopia prevalence has also been rapid, suggesting enviro

232 ald Tan, MD, comprised recognized experts in myopia prevention and treatment, public health experts f

233 ve error and the development of personalized myopia prevention strategies in the future.

234 0.025%, and 0.01% atropine eye drops reduced myopia progression along a concentration-dependent respo

235 effective therapeutic interventions to limit myopia progression are also needed.

236 Slowing myopia progression could decrease the risk of sight-thre

237 d treatment shown to be effective in slowing myopia progression in children.

238 act lenses significantly reduced the rate of myopia progression over 3 years compared with medium add

239 ght orthokeratology was effective in slowing myopia progression over a twelve-year follow-up period a

240 Adjusted 3-year myopia progression was -0.60 D for high add power, -0.89

241 ntration atropine is an emerging therapy for myopia progression, but its efficacy and optimal concent

242 tropical forest burning, we illustrate such myopia: Pursuit of short-term economic gains results in

243 Local staphylomata in high myopia reflect ocular asphericity and correlate with EOM

244 al interventions that may ultimately prevent myopia-related disease.

245 Myopia-related maculopathy is one of the leading causes

246 he first description of a nonsyndromic, high myopia-related, recessive RRD without any signs of vitre

247 howed markedly lower ORs for myopia and high myopia relative to Israeli-born controls or those arrivi

248 ma lutein concentrations and a lower risk of myopia requires replication.

249 curs, suggesting that the signals underlying myopia reside within the eye.

250 The myopia reversed when FD was discontinued, despite ONS, b

251 g evidence for a direct role of vitamin D in myopia risk.

252 Prevalence of myopia (spherical equivalence of <=-0.25 diopter [D]) an

253 chickens with optic nerve section (ONS), FD myopia still occurs, suggesting that the signals underly

254 Thirty high myopia subjects and fifty healthy subjects were enrolled

255 ea under the curve (ROC-AUC) >= 0.75 in high-myopia subjects compared to controls.

256 Healthy and high myopia subjects were imaged with the SS-OCTA system (PLE

257 (aged 13-15) showed a greater prevalence of myopia than elementary school students (aged 7-12) (55.8

258 Optix A09 refraction was 68.8 %, higher with myopia than hyperopia (90 % vs 54.5 %, p = 0.01).

259 srael were highly more likely to demonstrate myopia than those who arrived at an older age.

260 ounger adolescents (13-14 years of age) with myopia there was a significantly higher incidence of pat

261 was associated with a reduced adjusted OR of myopia; those in the highest tertile of years of educati

262 suggest RA changes with axial elongation in myopia to compensate for reduced retinal ganglion cell d

263 r of participants and a wider range of axial myopia to discern if contact lens correction has a great

264 Among children with myopia, treatment with high add power multifocal contact

265 patient satisfaction in eyes with very high myopia (VHM) above - 10.00 diopters (D).

266 t should be suspected in the setting of high myopia, vitreoretinal degeneration, and encephalocele.

267 opulation, the prevalence of myopia and high myopia was 42.0 and 2.0%, respectively, revealing a stat

268 background, usage of eyeglasses and parental myopia was assessed by a questionnaire before visual acu

269 Myopia was defined as a mean spherical equivalent of -0.

270 Myopia was defined as a spherical equivalent of less tha

271 Myopia was defined as non-cycloplegic subjective spheric

272 Prevalent myopia was defined as those who had >=2 ambulatory care

273 Incident myopia was defined by those who had at least 2 ambulator

274 Myopia was less prevalent among immigrants than Israeli-

275 The probability of myopia was marginally increased with increased screen ti

276 Myopia was more common among older age group 17-21 years

277 Myopia was not associated with any of the 5 DR outcomes

278 No long-term residual myopia was present after ONS alone, ruling out a surgica

279 The degree of myopia was variable among subjects, ranging from -6 to -

280 sm(s) underlying the pathophysiology of high-myopia, we conducted methylation profiling in 18 cases a

281 The factors found to be associated with myopia were as follows: more recent date of birth, femal

282 f demographic and socioeconomic factors with myopia were assessed, and trends over time were analyzed

283 n analysis showed that associated factors of myopia were body height (odds ratio [OR]: 1.05, 95% conf

284 Evaluated risk factors for myopia were collected, including family history of myopi

285 Differences between early and late-onset myopia were confirmed with DNA methylation patterns: the

286 Myopia and high myopia were defined based on right eye refractive data.

287 50 subjects; control group) without elevated myopia were included in the analysis.

288 Some known risk/protective factors of myopia were marginally significant: screen time (risk) a

289 Conjunctiva disorders, presbyopia and myopia were the commonest.

290 NS + FD eyes still retained -3 D of relative myopia when SHAM+FD animals had returned to normal).

291 Of 648 females, 50 (7.7%) had myopia while 33 (5.3%) of 623 males had myopia making fe

292 egression was used to see the association of myopia with age, sex, grade level, ethnicity, parental h

293 r are presented for the 307 eyes treated for myopia with astigmatism.

294 ria M2 MK are safe and effective in treating myopia with no statistically significant difference in i

295 The transient myopia with objective findings disappeared after the dis

296 To examine the association of myopia with ultraviolet B radiation (UVB; directly assoc

297 weakness and bone dysplasia as well as high myopia, with evidence of clinical improvement of motor f

298 s consumption could be associated with child myopia, with increased probability for girls and unexpec

299 Compared to patients with high myopia without staphyloma and normal controls, when stap

300 Only 36.1% of students with myopia wore eyeglasses when they attended the survey.