1 T acts both as N-terminal-lysine and glycine
myristoyltransferase.
2 development of new antimalarials targeting N-
myristoyltransferase.
3 (M)GXXX(S/T/A) in a reaction catalyzed by N-
myristoyltransferase.
4 nd NMT-2 comprise two distinct families of N-
myristoyltransferases.
5 N-myristoylation of AMPKbeta by the type-I N-
myristoyltransferase 1 (NMT1).
6 mal tethering of AMPK due to deficiency of N-
myristoyltransferase 1 (NMT1).
7 set to further explore the significance of N-
myristoyltransferase-
1 (NMT1) and TIMM17A expression ind
8 N-
myristoyltransferase-
1 (NMT1) catalyzes protein myristoy
9 lated with the catalytic efficiency of the N-
myristoyltransferase acting at the N terminus of the TRX
10 o increased in nmt1-181 yeast with reduced N-
myristoyltransferase activity.
11 of both proteins was attempted using human N-
myristoyltransferase and [(3)H]myristoyl-CoA.
12 AtCPK5 was a substrate for plant N-
myristoyltransferase and myristoylation was prevented by
13 m falciparum acetyl-coenzyme A synthetase, N-
myristoyltransferase,
and the cyclic guanosine monophosp
14 Our studies validate T. brucei N-
myristoyltransferase as a promising therapeutic target f
15 Northern and Western blot analyses plus N-
myristoyltransferase assays showed that Nmt is normally
16 on N-terminal myristoylation of MA by host N-
myristoyltransferase enzymes (NMTs), which recognize a s
17 lates the N-myristoylation of proteins via N-
myristoyltransferase enzymes (NMTs).
18 zymes with conserved binding sites, namely N-
myristoyltransferase from two different organisms, was s
19 opment, likely because it is the principal N-
myristoyltransferase in early embryogenesis.
20 armacological properties, but we find that N-
myristoyltransferase inhibitors (NMTi) phenocopy COPI in
21 red proteome with selective small-molecule N-
myristoyltransferase inhibitors.
22 MyristoylCoA:protein N-
myristoyltransferase is a member of the superfamily of G
23 We demonstrate that N-
myristoyltransferase is an essential and chemically trac
24 Inhibition of this target-T. brucei N-
myristoyltransferase-
leads to rapid killing of trypanoso
25 The trypanosomatids possess a single N-
myristoyltransferase (
NMT) and multiple palmitoyl acyltr
26 MyristoylCoA:protein N-
myristoyltransferase (
Nmt) attaches myristate to the N-t
27 N-
myristoyltransferase (
NMT) attaches the fatty acid myris
28 The promising drug target N-
myristoyltransferase (
NMT) catalyses an essential protei
29 N-
Myristoyltransferase (
NMT) catalyses the attachment of t
30 N-
Myristoyltransferase (
NMT) catalyzes the cotranslational
31 MyristoylCoA:protein N-
myristoyltransferase (
NMT) covalently attaches the 14-ca
32 Because cancer cells often have increased N-
myristoyltransferase (
NMT) expression, NMTs were propose
33 cs combined with potent and specific human N-
myristoyltransferase (
NMT) inhibition.
34 N-
myristoyltransferase (
NMT) is a promising antimalarial d
35 N-
Myristoyltransferase (
NMT) is a prospective drug target
36 to determine whether myristoyl-CoA:protein N-
myristoyltransferase (
Nmt) is a target for development o
37 N-
Myristoyltransferase (
NMT) is an attractive antiprotozoa
38 N-
Myristoyltransferase (
NMT) is an essential eukaryotic en
39 N-
myristoyltransferase (
NMT) is an essential eukaryotic en
40 The enzyme N-
myristoyltransferase (
NMT) is an essential protein, whic
41 N-
Myristoyltransferase (
NMT) represents a promising drug t
42 N-
Myristoyltransferase (
NMT) represents a promising drug t
43 ns produces a single myristoyl-CoA:protein N-
myristoyltransferase (
Nmt) that is essential for its via
44 N-
Myristoyltransferase (
NMT) transfers myristate to an ami
45 Inhibitors of Leishmania N-
myristoyltransferase (
NMT), a potential target for the t
46 Design of inhibitors for N-
myristoyltransferase (
NMT), an enzyme responsible for pr
47 N-
Myristoyltransferase (
NMT), an enzyme ubiquitous and ess
48 yzed by myristoyl-coenzyme A (CoA):protein N-
myristoyltransferase (
NMT), an enzyme ubiquitous in euka
49 Protein N-myristoylation is catalysed by N-
myristoyltransferase (
NMT), an essential and druggable t
50 lation is catalyzed by an enzyme activity, N-
myristoyltransferase (
NMT), which transfers myristic aci
51 alyzed by the enzyme myristoyl-CoA:protein N-
myristoyltransferase (
NMT).
52 MyristoylCoA:protein N-
myristoyltransferase (
Nmt, EC 2.3.1.97), a member of the
53 ivity by blockade of myristoylCoA: protein N-
myristoyltransferase (
NMT; EC 2.1.3.97).
54 tedly, we find that human N-terminal glycine
myristoyltransferases (
NMT) 1 and 2 can efficiently myri
55 N-
myristoyltransferases (
NMT) catalyze co- or posttranslat
56 EGR2 is N-myristoylated by N-
myristoyltransferase NMT1 at 22 degrees C, which is impo
57 pharmacologic evidence that inhibiting the N-
myristoyltransferase NMT1 suppresses cell-cycle progress
58 ristoylation enzymes, involving one or two N-
myristoyltransferases (
NMT1 and NMT2), among which NMT1
59 haromyces cerevisiae myristoyl-CoA:protein N-
myristoyltransferase (
Nmt1p) is an essential 455-residue
60 charomyces cerevisiae myristoylCoA:protein N-
myristoyltransferase (
Nmt1p) is an essential enzyme that
61 MyristoylCoA:protein N-
myristoyltransferase (
Nmt1p) is an essential enzyme whos
62 he essential enzyme, myristoyl-CoA:protein N-
myristoyltransferase (
Nmt1p).
63 N-
myristoyltransferases (
NMTs) cotranslationally transfer
64 n be catalyzed during protein synthesis by N-
myristoyltransferases (
NMTs), and its dysregulation has
65 This reaction is catalyzed by N-
myristoyltransferases (
NMTs), which transfer myristate f
66 ipid A, we overexpressed the lauroyl- or the
myristoyltransferase of lipid A biosynthesis, encoded by
67 y, coexpression of a K7,9A-Fyn mutant with N-
myristoyltransferase restored myristoylation, membrane b
68 results from retinal enrichment of unusual N-
myristoyltransferase substrates.
69 Trypanosoma brucei N-
myristoyltransferase (
TbNMT) is an attractive therapeuti
70 This reaction is catalyzed by a N-
myristoyltransferase that uses myristoyl-coenzyme A as s
71 The method uses the eukaryotic enzyme N-
myristoyltransferase to modify the N-terminus of the pro
72 One such putative target is the enzyme N-
myristoyltransferase,
which catalyses the attachment of
73 inical stage pharmacological inhibitors of N-
myristoyltransferases,
which reduce tumor growth in xeno
74 By co-expressing yeast N-
myristoyltransferase with an elastin-like polypeptide (E