ライフサイエンスコーパス: naive

1 udy agent; the majority (65%) were treatment naive.

2 new influenza A strains to which humans are naive.

3 inclusive) with HIV-1 infection who were ART naive.

4 Taken together, these findings indicate that naive adaptation is a regulated process in H. volcanii t

5 , observational study conducted in treatment-naive, adult Taiwanese patients with nAMD.

6 cART-naive adults (>=18 years) initiating INSTI-, PI-, or NNR

7 udy in HIV-1-infected antiretroviral therapy-naive adults (CD4+ >=50 cells/mm3).

8 ti-CSP antibody responses in healthy malaria-naive adults (N=45) vaccinated with RTS,S/AS01.

9 Consistent with this, NK cells of malaria-naive adults upregulated PD-1 following P. falciparum st

10 who received IMV.Methods: We assessed opioid-naive adults who were admitted to an ICU, received IMV,

11 A by more than 1.0 log at day 7 in treatment-naive adults with HIV-1 infection and were generally wel

12 lind, placebo-controlled study of 36 malaria-naive adults, all CVac subjects received chloroquine pro

13 enced resident AMs remain largely similar to naive AMs.

14 the family of related sequences that share a naive ancestor to predict the affinity of each resulting

15 zophrenia subjects (N = 36, 19 antipsychotic-naive and 17 antipsychotic-treated) and healthy controls

16 Twenty percent of treatment-naive and 34.8% of non-naive patients had a week-4 CRT t

17 acy of 67.0% (95% CI: 53.6 - 76.5) in dengue-naive and 89.2% (82.4 - 93.3) against hospitalized dengu

18 arget ROS1 fusion proteins in both treatment-naive and acquired-resistance settings.

19 apeutic approach to treat metastatic hormone-naive and castration-resistant prostate cancer.

20 ith intermediate characteristics compared to naive and central memory T cells.

21 ical NF-kappaB pathways, and thus stimulates naive and co-stimulates IL-33-activated ILC2s.

22 nal cells and retinal endothelial cells from naive and EAU mice were sorted and their gene expression

23 (+) memory T cells can have features of both naive and effector cells has forced the field to struggl

24 ofile the alphabeta TCR repertoires of human naive and effector/memory CD4(+) T-cell subsets, irrespe

25 een well tolerated and safe in >1526 malaria-naive and experienced 6-month to 65-year-olds in the Uni

26 ed stem cells (EpiSCs) represent the initial naive and final primed phases of pluripotency, respectiv

27 nd decreases depressive behavior in sexually naive and late postpartum female mice respectively, with

28 outside the MB implicated in integration of naive and learned responses.

29 ing and TCR sequencing, to dissect the human naive and memory CD4+ T cell repertoire against the infl

30 imulation of memory T cells and screening of naive and memory T cell libraries, combined with T cell

31 receptor internalization in tissue from both naive and morphine-treated animals, suggesting that GRK2

32 After TAK-003 vaccination, all samples from naive and preimmune vaccinees completely abrogated DENV-

33 intravitreal dexamethasone implants (IDI) in naive and previously treated (PT) diabetic macular edema

34 XPSCs represent a pluripotency state between naive and primed pluripotency and harbor molecular, cell

35 ify and generate llama nanobodies (VHH) from naive and synthetic humanized VHH phage libraries that s

36 particularly for individuals who are dengue-naive and those younger than 9 years.

37 vity versus IFN beta-1a (including treatment-naive and younger patients) and resulted in less disabil

38 19/294 developed RA; the risk-score included naive and/or Treg and predicted progression (p < 0.0001)

39 e antisera from immunized, convalescent, and naive animals (n = 172).

40 cortex was more engaged when expert but not naive animals controlled the cursor.

41 for blood to perform needle inoculations in naive animals for tick feeding studies.

42 In naive animals the MLI responses did not differ between t

43 In naive animals, Nod2 operates downstream of TCR ligation

44 In slices from naive animals, pharmacological inhibition of G-protein r

45 nor Ags at a similar magnitude to T cells of naive animals, suggestive of the localized nature of tol

46 fect on desensitization in tissue taken from naive animals.

47 Importantly, all these pDCexos primed naive antigen-specific CD8 T cells only in the presence

48 Naive approaches for dealing with observation delays, su

49 and Cbl-b (Cbls), which consequently control naive B and cognate T follicular helper (Tfh) cell inter

50 The mature naive B cell repertoire consists of three well-defined p

51 ppear much more frequently than predicted in naive B cell repertoires.

52 he factors determining whether an individual naive B cell will proliferate following Ag encounter rem

53 , and also binds to its putative receptor on naive B cells and activated T cell subsets.

54 Memory and Naive B cells are good potential predictors of LC and HC

55 Mature naive B cells expressing BCRs of the IgM and IgD isotype

56 Functionally, naive B cells expressing moderate levels of Nur77 are mo

57 bility to inhibit antibody production by new naive B cells in an antigen-specific manner.

58 rcentages of transitional B cells decreased, naive B cells increased, and senescent CD8 T cells decre

59 uiting preexisting memory B cells as well as naive B cells into the response.

60 his regulation may facilitate recruitment of naive B cells with a low-affinity BCR into GCs to initia

61 rts by detecting virally infected memory and naive B cells, but also identified cell-associated genom

62 sils produced IL-10 following stimulation by naive B cells, which promoted B cell immunoglobulin G (I

63 phenotype possessing the ability to suppress naive B cells.

64 ormed to determine (177)Lu-NM600 toxicity in naive BALB/C mice administered 9.25 or 18.5 MBq.

65 stop+A4G RSV were attenuated in cells and in naive BALB/c mice compared to that for wild-type RSV, th

66 hine, random forest, logistic regression and Naive Bayes.

67 er," was defined as a patient who was opioid-naive before surgery and subsequently filled at least 1

68 om the in vitro system were able to infect a naive bovine host.

69 w here that antigen uptake and processing by naive but not GC B cells depend on Cbl and Cbl-b (Cbls),

70 also blocked by compound 101 in slices from naive but not morphine-treated animals.

71 measures to the matched checkpoint treatment naive Cancer Genome Atlas (TCGA) samples where cytolytic

72 8(+) T cells, with the highest expression on naive CD4 and CD8(+) T-cell subsets.

73 We have examined the priming of naive CD4 T cells in vitro at fever temperatures, and we

74 -specific metabolic signature, which enables naive CD4 T cells to differentiate into pro-inflammatory

75 iation, a complex process in which quiescent naive CD4 T cells undergo transcriptional changes to eff

76 However, when naive CD4 T cells were primed via antigen and dendritic

77 eptor (TCR) deep sequencing, tetramer-guided naive CD4 T-cell precursor enumeration, and whole-body i

78 otoi-stimulated DCs induced proliferation of naive CD4(+) and CD8(+) T cells to a larger extent than

79 The frequency of naive CD4+ T cells correlated inversely with HTLV-1 pVL

80 Evaluating the risk of progression using naive CD4+ T-cells was predictive of progression along t

81 D4(+) T cells from PIV-vaccinated WT mice to naive CD4-deficient (CD4 KO) mice demonstrated that anti

82 In this study, we show that stimulation of naive CD8 T cells with agonistic CD3 and CD28 Abs, mimic

83 ines and present antigens to polarize mainly naive CD8(+) or CD4(+) T cells, respectively.

84 ecific ablation of Dot1L resulted in loss of naive CD8(+) T cells and premature differentiation towar

85 at targeted mutations can be introduced into naive CD8(+) T cells using CRISPR-based homology-directe

86 d the antigen-specific progeny of individual naive CD8+ T cells to the T effector (TEFF), T circulati

87 imal effect on the expansion of HBV-specific naive CD8+ T cells undergoing intrahepatic priming.

88 spread in a prion-like manner, by passing to naive cells in which it templates misfolding and aggrega

89 s formed from purified protein can transform naive cells to acquire [SMAUG(+)].

90 eased the transfer of alpha-syn pathology to naive cells.

91 However, the accuracy and precision of the naive CFR remain limited because 44% of survival outcome

92 vals) explained 93.6% of the variance in the naive CFR.

93 was unable to be horizontally transmitted to naive chickens, in contrast to the WT virus.

94 were acquired from 25 unmedicated, treatment-naive children and adolescents with OCD (12.8 +/- 2.9 ye

95 Previously intervened and intervention-naive children were not mixed in the same cluster.

96 In 1995-2007, 7,091 insulin-naive Chinese patients (mean age 56.8 +/- 13.3 [SD] year

97 with obinutuzumab in patients with treatment-naive chronic lymphocytic leukaemia.

98 Sixty-eight patients with purine analog-naive classic HCL were randomly assigned 1:1 to concurre

99 equences that specifically bind molecules on naive complex biological samples like cells or tissues.

100 y lower than both the corresponding crude or naive confirmed case fatality risk (2,169/48,557 = 4.5%)

101 Most surprising was that the simple naive conservation approach using PSI-BLAST in many case

102 d 24 recently BCG-vaccinated adolescents and naive controls.

103 m2+/+ mice were indistinguishable from their naive counterparts in Tgm2-/- mice with no signs of clon

104 rity trial was conducted among polio vaccine-naive Cuban infants who received 2 IPV doses at 4 and 8

105 Naive culture conditions minimize epigenetic fluctuation

106 plus ipilimumab for anti-PD-1 or anti-PD-L1-naive disease, and durvalumab plus tremelimumab for anti

107 PD-1 or anti-PD-L1 therapy for immunotherapy-naive disease, and three (5.4%) of 56 responded to docet

108 Serum samples from 39 steroid-naive DMD boys 4 to <7 years enrolled into a clinical tr

109 ding gadopentetate dimeglumine, and two GBCA-naive donors were also evaluated.

110 all-trans retinoic acid (ATRA) in treatment-naive elderly patients with acute myeloid leukemia (AML)

111 fected with suppressed HIV: 5 of 6 treatment-naive enrollees completed A5335S.

112 phageal biopsies from 36 Caucasian treatment naive EoE patients at diagnosis.

113 ion to a tankyrase inhibitor-regulated human naive epiblast-like pluripotent state.

114 We identified 3429 treatment-naive eyes (395 receiving bevacizumab, 1138 receiving af

115 We analyzed 712 treatment-naive eyes (ANZ, n = 474; Switzerland, n = 321) starting

116 Anti-VEGF-naive eyes diagnosed with nAMD that commenced treatment

117 nretinal photocoagulation (PRP) in treatment-naive eyes with proliferative diabetic retinopathy (PDR)

118 ccessfully identified the first-episode drug-naive (FEDN) schizophrenia patients (accuracy 78.6%) and

119 bility of pup calls in mothers compared with naive females.

120 vely sculpt the emergent responses, visually naive ferrets were exposed to several hours of experienc

121 ynamic and progresses through a continuum of naive, formative and primed states.

122 Pluripotent cells emerge as a naive founder population in the blastocyst, acquire capa

123 with a large number of missing or incorrect naive genotype calls, which can be improved by identifyi

124 were not previously intervened (intervention-naive group).

125 We analysed 400 consecutive treatment-naive HBV-monoinfected patients: 49% males, median age 3

126 y of REP 2139-Ca against HDV in 12 treatment-naive HBV/HDV co-infected patients.

127 ctive T cell lines generated from SARS-CoV-2-naive healthy donors responded similarly to the C-termin

128 re we show that short (3.4 s) tVNS pulses in naive healthy male volunteers induced transient pupil di

129 rmalities, with increased activated T cells, naive helper T (Th) and cytotoxic T cells, loss of CD56b

130 otal helper T lymphocyte proportions and low naive helper T cell proportions are associated with thos

131 we found that expression of Nurr1 in l-DOPA naive hemi-parkinsonian rats resulted in the formation o

132 In treatment-naive HGSOC, we found that immune-cell-excluded and infl

133 ver that miR-371-373 are highly expressed in naive hPSC.

134 es, and thus their relationship to authentic naive human B cell BCR sequences and affinities is uncle

135 Here we show that resetting from primed to naive human pluripotency results in acquisition of a DNA

136 Transfer of NETs to naive human PMNs prompts additional NET release, promoti

137 Specifically, we screened a naive human semisynthetic phage library against RBD, lea

138 the eOD-GT8 60mer, we tested each authentic naive human VRC01-class BCR mouse model under rare human

139 ether, these experiments utilizing authentic naive human VRC01-class BCRs validate a central tenet of

140 Rapid desensitization of naive, IgE-sensitized huFcepsilonRIalpha mice and huFcep

141 (<24 h) and this early response was free of naive IgG-SCs.

142 We also adoptively transferred naive IL-4Ralpha(-/lox) or IL-4Ralpha(-/-) B cells into

143 determining region 3 (HCDR3) loops from MARV-naive individuals and one from a previously MARV-infecte

144 We collected Vpu isolates from 332 treatment-naive individuals living with chronic HIV-1 infection in

145 tor outcomes as compared with corticosteroid-naive individuals over an 18-month treatment period.

146 In total, 14 919 ARV drug-naive individuals were included.

147 -cell profiling of T cells from chemotherapy-naive individuals with non-small-cell lung cancer identi

148 icantly increased DENV-2 NS1-specific IgG in naive individuals, which cross-reacted with DENV-1, -3,

149 een January 2019 and March 2020 on screening-naive individuals.

150 in multigenerational family units, from DENV-naive infants to grandparents with multiple prior DENV e

151 Compared to BCG-naive infants, BCG-vaccinated infants had increased prod

152 nts of HCV-viremic (RNA positive) versus HCV-naive kidneys.

153 ive prey consume considerably more prey than naive larvae.

154 nitude higher than unoptimized peptides from naive library screening.

155 The naive-like B cells are decreased in advanced NSCLC, and

156 Co-culture of isolated naive-like B cells from NSCLC patients with two lung can

157 lung cancer cell lines demonstrate that the naive-like B cells suppress the growth of lung cancer ce

158 in response to sensory input, compared with naive littermate controls.

159 increased perineuronal nets in the brains of naive littermates, suggesting a new role for microglia a

160 Using a naive llama single-domain antibody library and PCR-based

161 row mononuclear cells (BMNC) are a source of naive macrophages capable of reducing joint inflammation

162 ed if they received therapeutic ERCP and had naive major duodenal papilla.

163 ice respectively, with no effect on sexually naive male mice.

164 Here, we investigated whether naive MBP-specific CD8+ T cells recruited to the CNS dur

165 Forty-eight medicine-naive MDD patients plus 33 healthy controls (HC) matched

166 C patients consisted of >35% ARG1-expressing naive MDSCs (HLA-DR(-)CD33(-)CD11b(-)CD14(-)CD15(-)MDSCs

167 Airway sensitization of naive mice with RSV-infected BMDCs exacerbate a live cha

168 esponding to stimulus features were found in naive mice, and training did not generate neurons with e

169 In treatment-naive mice, MYCN overexpression promoted cell cycle prog

170 stinguishing features between vaccinated and naive mice.

171 by bone marrow transplantation to recipient naive mice.

172 this cohort of subjects with or without ICS-naive mild asthma.

173 stinct cytokine/chemokine footprint from the naive monocyte, and that TNF-alpha was the most sensitiv

174 hich are the most highly expressed miRNAs in naive mouse PSC.

175 concept study, we supplemented PA to therapy-naive MS patients and as an add-on to MS immunotherapy.

176 chenne Natural History Study (corticosteroid-naive, n = 19; corticosteroid-treated, n = 68) over a si

177 ab administration in patients with treatment-naive nAMD were first demonstrated in the SEE Phase 1/2

178 Recent data have highlighted how the naive, neonate-like immune system of specific pathogen-f

179 ly pyrin domain-containing 3 inflammasome in naive neutrophils and promote interleukin-1beta secretio

180 onal T cells paralleled these findings, with naive Nur77 expression distinguishing T(FH) cell potenti

181 collateral sensitivities, absent in therapy naive or fully resistant cells, suggesting the potential

182 measure anti-DENV NS1 IgG in sera from DENV-naive or preimmune subjects pre- and postvaccination wit

183 ur objective was to compare TL in HIV+ (cART-naive or treated) and HIV-negative children with and wit

184 Infected mice remained naive or were treated with the reverse transcriptase (RT

185 16, who were either newly diagnosed and cART-naive, or on cART for >6 months, and HIV-negative contro

186 le safety profile in patients with treatment-naive, or relapse or refractory Waldenstrom macroglobuli

187 were examined for their ability to polarize naive OVA-TCR transgenic CD4(+) T cells.

188 d macroscopic skin alterations compared with naive (P < 0.0001) and syngeneic controls (P = 0.0023).

189 harm calculations were restricted to aspirin-naive participants <70 years of age not at high risk of

190 etween vamorolone-treated and corticosteroid-naive participants (p = 0.088; least squares [LS] mean 0

191 ent compared to group-matched corticosteroid-naive participants for run/walk 10 meters velocity (p =

192 We studied ART-naive participants from the ADVANCE study randomized to

193 In Part 1, healthy, malaria-naive participants received 800 mg KAF156 or placebo thr

194 aplasticity is buffered by the presence of a naive partner.

195 tress transmission happens in nearly half of naive partners and stress buffering occurs in approximat

196 ale stressed mice that closely interact with naive partners.

197 with more time engaged in allogrooming from naive partners.

198 cient of variation ratio (CVR) in medication-naive patients (logCVR = -0.49 [95% CI, -0.78 to -0.20],

199 motherapy-treated patients compared to chemo-naive patients (P < 0.05).

200 median follow-up of 24.2 months in treatment-naive patients and 21.5 months in relapsed or refractory

201 At that time, 67% of treatment-naive patients and 50% of relapsed or refractory patient

202 regarding the types of care for which opioid-naive patients are provided initial opioid prescriptions

203 ver, shotgun metagenomic data from treatment-naive patients are scarce hampering comprehensive analys

204 re no differences between treatments in drug-naive patients at low cardiovascular risk.

205 A higher percentage of treatment-naive patients gained 10 or 15 letter or more in BCVA (P

206 percent of treatment-naive and 34.8% of non-naive patients had a week-4 CRT that was >35 mum thicker

207 The whole group of antipsychotic-naive patients had lower levels of GABA in dorsal ACC (p

208 nd time to viral suppression among 1419 drug-naive patients in the Swiss HIV Cohort Study.We performe

209 15 patients were identified; 54.6% of opioid naive patients received a perioperative opioid prescript

210 Intravitreal anti-VEGF naive patients seen between 2010 and 2019 of White (W) r

211 We identified 15,657 opioid-naive patients who underwent a range of surgical procedu

212 In a phase 1 study of treatment-naive patients with chronic HBV infection, all doses tes

213 nt cohorts of patients with CD: 116 biologic-naive patients with early-stage CD (validation cohort 1)

214 In most treatment-naive patients with nAMD, vision gains were achieved at

215 In total, 56 antipsychotic-naive patients with schizophrenia or psychotic disorder

216 Importantly, in ablation-naive patients, atrial LGE is associated with electrogra

217 h edoxaban were seen in vitamin K antagonist naive patients, patients with CHADS(2) scores 4 to 6, an

218 ith suspected local relapse, and 6 treatment-naive patients.

219 92,018 opioid prescriptions filled by opioid-naive patients.

220 lymorphic mutations were those in <1% of ARV-naive persons.

221 e to linkage disequilibrium is widespread in naive phenome-wide association studies of proteins.

222 1 +/- 1.9%, after: 58.8 +/- 5.2%) and mature naive phenotypes (before: 45.5 +/- 3.1%, after: 25.1 +/-

223 activating a subset of genes, including the naive pluripotency and germline marker Dppa3 (Stella, Pg

224 Moreover, naive pluripotency during embryonic development coincide

225 Finally, interfering with abscission impairs naive pluripotency exit, and artificially inducing absci

226 revealed that reprogramming into primed and naive pluripotency follows diverging and distinct trajec

227 t global hyperactivation of enhancers drives naive pluripotency, and this can be achieved in vitro by

228 for lineage commitment, and reprogramming to naive pluripotency.

229 early human embryos, and in both primed and naive pluripotent culture conditions.

230 idence of oncogenic polymorphisms arising in naive pluripotent stem cells is close to zero.

231 of RNA sequencing (RNA-seq) data from human naive pluripotent stem cells reported multiple point "mu

232 unique feature of mammalian development and naive pluripotent stem cells.

233 Adult, treatment-naive PLWH in the Vanderbilt Comprehensive Care Clinic c

234 toration to health in antiretroviral therapy-naive PLWH, which is compounded by the rising rates of o

235 can lead to pandemics in an immunologically naive population.

236 f CD8(+) T cell families derived from single naive precursors, we find that fate decisions made durin

237 thod optimized on DMS data (Envision), and a naive prediction using conservation information from hom

238 nal validation defined the transcriptomes of naive progenitors and erythroid-, megakaryocyte-, and le

239 SMA) PET/CT for primary staging of treatment-naive prostate cancer patients is still under debate.

240 Consecutive biologic naive psoriasis patients (n=209) underwent coronary comp

241 CI, 0.19-0.24) in the presence of treatment-naive quiescent type 1 CNV and by a factor of 0.46 (95%

242 immunosorbent assay (ELISA) using sera from naive rabbits and rabbits with S. aureus-mediated osteom

243 Naive rats and mice were used for in vivo PET kinetic st

244 The comparison of gene's family usage in naive rats have been used to validate the frequency's di

245 We additionally determined that in l-DOPA-naive rats striatal rAAV-Nurr1 overexpression (1) increa

246 , when compared with nociceptors from opioid naive rats.

247 s with low addiction-like behaviors (LA) and naive rats.

248 neutrophils from beta-glucan-trained mice to naive recipients suppressed tumor growth in the latter i

249 We investigated the disturbances of naive, regulatory and inflammation related cell (IRC) CD

250 sity of CDR structures and these patterns of naive repertoire paratope usage are highly conserved acr

251 atients treated with DAA, IFN, and antiviral naive, respectively (P < 0.001).

252 -infected patients, highlighting stereotyped naive responses to this virus.

253 can be screened, thus allowing campaigns of naive scFv libraries to be selected against membrane pro

254 nt response prediction in first-episode drug-naive schizophrenia, which could complement other biomar

255 toires are available that represent both the naive state (i.e. antigen-inexperienced) and that after

256 y miR-143-3p and miR-22-3p as markers of the naive state and miR-363-5p, several members of the miR-1

257 PSCs can be stabilized in the naive state by blocking extracellular differentiation st

258 d by permissive epigenomic signatures in the naive state, indicating that they are poised for express

259 n during early differentiation, we find that naive stem cells release their plasma membrane from the

260 CCR7, CD27, CD28, and CD40L-suggestive of a naive T cell (TN).

261 eport an unexpected heterogeneity within the naive T cell compartment in mice, where loss of VISTA di

262 cking to inflamed tissues, without affecting naive T cell entry into secondary lymphoid organs.

263 f robust T cell activation to encompass both naive T cell homeostasis and models of weak activation,

264 Although a critical player in naive T cell homeostasis, the ability of VISTA to restra

265 The diversity of the naive T cell repertoire drives the replenishment potenti

266 omeostasis, the ability of VISTA to restrain naive T cell responses was lost under inflammatory condi

267 loss of VISTA disrupted the major quiescent naive T cell subset and enhanced self-reactivity.

268 tion of high endothelial venules to increase naive T cell trafficking to the lymph nodes.

269 Immature and naive T cells are present in both healthy and atheroscle

270 t transendothelial migration (diapedesis) of naive T cells by modulating molecular assembly the at T

271 When dormant naive T cells first become activated by antigen-presenti

272 reveal the presence of a broad repertoire of naive T cells specific for cryptic H1-HA peptides and de

273 VISTA is therefore a distinctive NCR of naive T cells that is critical for steady-state maintena

274 ell subsets and the plasticity of individual naive T cells to adopt different fates.

275 uding dendritic cells and monocytes instruct naive T cells to differentiate into various effector cel

276 Scarcity of naive T cells was also associated with aging and poor di

277 Naive T cells were cocultured with pDCs in specific stra

278 train-dependent, MHC class II disparity with naive T cells, which may explain organ- and strain-speci

279 of T cell activation (VISTA) is expressed on naive T cells.

280 d increased memory T cells at the expense of naive T cells.

281 optimizes their ability to efficiently prime naive T cells.

282 Naive T(H) cells cocultured with PN-stimulated mDCs show

283 l differentiation, mDCs were cocultured with naive T(H) cells.

284 predicting treatment-induced remission using naive T-cells had an odds ratio of 15.4 (p < 0.0001).

285 Our analyses revealed that naive TF target genes are more likely to be TFs themselv

286 ive TFs, suggesting denser hierarchies among naive TFs.

287 effective in models of NF1-MPNST, both those naive to and those resistant to MEKi, as well as in the

288 ally learn the other option than individuals naive to both options.

289 (CD4+CD38+DR+) T cells in 586 women who were naive to highly active antiretroviral therapy.

290 subcutaneous formulation in patients with HS naive to or having failed anti-TNF therapy.

291 plantation, the epiblast (Epi) transits from naive to primed pluripotency, before giving rise to the

292 es of moderate-complexity RRD will be chosen naive to surgeon, surgery, and outcome for subgroup anal

293 e present a comprehensive miRNA profiling of naive-to-primed transition in hPSC, a process recapitula

294 This efficiently stabilizes the naive transcriptional program and confers resistance to

295 enomic landscapes of five distinct treatment naive tumors, a papillary transitional cell renal cell c

296 ed with increased levels of AXL in treatment-naive tumors.

297 In this work, we outline the steps for a naive user to approach the Geometry-preserving Adaptive

298 ving 1 injection was significantly higher in naive vs PT DME eyes (76.1 vs 47.7), (p < 0.001).

299 Thirty-nine percent were treatment naive ("watch and wait"), while 61% had received >=1 CLL

300 ome analysis in a large cohort of medication-naive youth at risk for psychosis from the Shanghai At R