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1 id detection of trypsin activity even at sub-nanomolar concentration.
2 n, tube formation, and microvessel growth at nanomolar concentration.
3 s in a few minutes with both partners at low nanomolar concentration.
4 nt perchlorate in vegetable matrices down to nanomolar concentration.
5 d inhibitor and inhibits irreversibly MPO at nanomolar concentration.
6 of HIV envelope protein gp120 to DC-SIGN at nanomolar concentrations.
7 and was able to block cancer cell growth at nanomolar concentrations.
8 the growth of medulloblastoma D283 cells at nanomolar concentrations.
9 N) uncouples mammalian mitochondria at upper nanomolar concentrations.
10 novel kinase complex from infected cells at nanomolar concentrations.
11 ed cell death in primary cultured neurons at nanomolar concentrations.
12 MIF trimer that binds and activates CD74 at nanomolar concentrations.
13 ncentration and inhibited cell growth at low nanomolar concentrations.
14 ization state, all at biologically relevant, nanomolar concentrations.
15 ell growth of different human tumor cells at nanomolar concentrations.
16 ed kinases such as the oncogenic PIM1 at low nanomolar concentrations.
17 ess effective and lose their efficacy at low nanomolar concentrations.
18 r than as a canonical tetramer at mid-to-low nanomolar concentrations.
19 luted whole blood at clinically relevant low-nanomolar concentrations.
20 inhibited the HIV-1 WT in MT-4 cells at low nanomolar concentrations.
21 chemotactic activity for T(H)2 cells at low nanomolar concentrations.
22 erentiation in MSCs and preadipocytes at low nanomolar concentrations.
23 al, kills Plasmodium falciparum parasites at nanomolar concentrations.
24 nds histones, DNA, and intact nucleosomes at nanomolar concentrations.
25 tion facilitates carrier-free cell uptake at nanomolar concentrations.
26 tive against various insults in vitro at low nanomolar concentrations.
27 vation in these cells, impaired viability at nanomolar concentrations.
28 ic antisense effects are demonstrated at low nanomolar concentrations.
29 s (AZD1152, MK-0457, and PHA-739358), at low nanomolar concentrations.
30 d by either resolvin E1 or RvD1 at bioactive nanomolar concentrations.
31 DI, APT-6K, exerted bactericidal activity at nanomolar concentrations.
32 d redox reactions that activate PPARgamma at nanomolar concentrations.
33 tyrosine, and D-tryptophan that could act at nanomolar concentrations.
34 m displayed selective anti-HIV-2 activity at nanomolar concentrations.
35 pancreatic cancer cells at low micromolar to nanomolar concentrations.
36 and reduces cancer cell clonogenic growth at nanomolar concentrations.
37 hesis of KLYP956, which inhibits iNOS at low nanomolar concentrations.
38 ctericidal functions in human neutrophils at nanomolar concentrations.
39 uced HIF-1 reporter activity at single-digit nanomolar concentrations.
40 w that DJ-1 is sufficient for RNA binding at nanomolar concentrations.
41 dependent Pseudomonas aeruginosa biofilms at nanomolar concentrations.
42 ls treated with NSC 725776 and NSC 724998 at nanomolar concentrations.
43 ell lines from various organs and tissues at nanomolar concentrations.
44 ell growth of many different cancer types at nanomolar concentrations.
45 milar to that of intracellular CO release at nanomolar concentrations.
46 so showed significant anticancer activity at nanomolar concentrations.
47 unprecedented sensitivity for Zn(2+) at sub-nanomolar concentrations.
48 tively engages cellular menin protein at low nanomolar concentrations.
49 ty to hCD80 and displaced CTLA-4 and CD28 at nanomolar concentrations.
50 depress the cortical network activity at low nanomolar concentrations.
51 cts of exposure to a drug valinomycin at sub-nanomolar concentrations.
52 ALF34, which induces pollen tube bursting at nanomolar concentrations.
53 o amyloid structures and disrupt membrane at nanomolar concentrations.
54 t cell-based antiproliferative activities in nanomolar concentrations.
55 d to the two S. typhymurium OASS isoforms at nanomolar concentrations.
56 cer) and PF-04217903 block their activity at nanomolar concentrations.
57 ncer drugs were sensitive to flubendazole in nanomolar concentrations.
58 e a potent UVA photosensitizer, effective at nanomolar concentrations.
59 e mediators, the cytokines, which act at sub-nanomolar concentrations.
60 nal was observed for all three conjugates at nanomolar concentrations.
61 nonical and noncanonical NLRP3 activation at nanomolar concentrations.
62 The dyes inhibited parasite proliferation at nanomolar concentrations (0.019-1.83 muM) and a synergis
65 ion-cultured cell media within 10 min at low nanomolar concentrations, a response that is typical of
67 rs less toxic than PLTX, its cytotoxicity at nanomolar concentrations after short exposure time rises
68 N-DABOs) are interesting compounds active at nanomolar concentration against wild type of RT and with
69 es with improved antiproliferative activity (nanomolar concentrations) against several cancer cell li
70 This was achieved at biologically relevant, nanomolar concentrations, allowing determination of pona
72 ppocampal neurons showed that S1P applied at nanomolar concentration alters the distribution of Synap
74 urified alphaVbeta3 integrin receptor at low nanomolar concentration and showed in vitro cytotoxic ac
75 ad range of conditions, including storage at nanomolar concentration and under ambient conditions.
76 nd peripheral blood mononuclear cells at low nanomolar concentrations and displays excellent potency
77 unctional compounds potently inhibit HDAC at nanomolar concentrations and either agonize or antagoniz
78 f VHR that inhibit its enzymatic activity at nanomolar concentrations and exhibit antiproliferative e
79 ]JW199, labels active NCEH1 in live cells at nanomolar concentrations and greater than 1000-fold sele
81 preferential cytotoxicity towards PEL at low nanomolar concentrations and is approximately 10 and 100
82 ctively inhibits leukemia cell growth at low nanomolar concentrations and is capable of achieving par
83 The effect of BTP2 on TRPM4 occurs at low nanomolar concentrations and is highly specific, because
84 and 25 selectively inhibited L. donovani at nanomolar concentrations and showed much lower cytotoxic
85 K enzyme (alphaK(a) = 39 nM) in vitro at low nanomolar concentrations and significantly reduced gluco
86 sing liquid scintillation counting (LSC) for nanomolar concentrations and thermal ionization mass spe
87 1-NaV1.4, NaV1.6-NaV1.7) that are blocked by nanomolar concentrations and TTX-resistant (TTX-r) chann
89 H589, MS275, and largazole were effective at nanomolar concentrations and were 10(4) to 10(5) times m
90 ed as selective live cell imaging probes (at nanomolar concentrations) and stained lipid-based struct
91 zylidene-hydrazide) activated neutrophils at nanomolar concentrations, and Ca(2+) mobilization was in
92 re characteristic for individual proteins at nanomolar concentrations, and can be quantitatively diff
93 ear translocation was blocked by SNX-7081 at nanomolar concentrations, and cytokine production was po
94 o MTs, causes cell cycle arrest in G(2)/M at nanomolar concentrations, and retains antiproliferative
95 ecessary for antiangiogenic effects, whereas nanomolar concentrations are effective for endocrine inh
97 ecific detection of oxytetracycline (OTC) at nanomolar concentrations based on a microfabricated cant
98 The protein appears to exist as a dimer at nanomolar concentrations but can form larger assemblies
99 in a petunia suspension culture bioassay at nanomolar concentrations, but they did not induce the ex
100 lipase A(2) (gIIA PLA(2)) kills S. aureus at nanomolar concentrations by an action(s) that depends on
101 hibits human immunodeficiency virus (HIV) at nanomolar concentrations by binding to high mannose suga
103 oxic compounds known to kill cancer cells at nanomolar concentrations by targeting the microtubule ne
105 We further show that gingipains, even at low nanomolar concentrations, cleaved SPINK6 in concentratio
106 ion in both MSCs and in preadipocytes at low nanomolar concentrations comparable to those that have b
107 tro, paclitaxel was found to be effective at nanomolar concentrations, complement therapy with temozo
110 It detects tributyltin and triphenyltin in nanomolar concentrations (detection limits were found to
113 showed potent antiplasmodial activity at low nanomolar concentrations (EC50 <500 nM) and low cytotoxi
114 itions using only ~1 muL of liquid at dilute nanomolar concentrations, effectively reducing the amoun
115 stability of these complexes in methanol at nanomolar concentrations exceeds that of complexes betwe
116 n this study, we show that PG is required at nanomolar concentrations for pyoluteorin production in P
117 ulture studies, CCI-779 at the commonly used nanomolar concentrations generally confers a modest and
118 gp42 were indispensable for maintaining low-nanomolar-concentration gH/gL binding affinity and inhib
120 ds and proteins bearing aromatic residues at nanomolar concentration, i.e., a full order of magnitude
123 (3g), which inhibited cancer cell growth at nanomolar concentrations (IC50 values of 0.3-27 nM), bou
124 96 disturbed the microtubule dynamics at the nanomolar concentration in A375 and B16F10 melanoma cell
126 CH-3-8 disrupted microtubule dynamics at the nanomolar concentration in MIA PaCa-2 and PANC-1 pancrea
127 cumulation of model analyte (streptavidin at nanomolar concentration in nanoliter effective volume) d
129 s reduced the basal levels of p53 protein at nanomolar concentrations in a dose-, time-, and cancer c
131 racteristics that provide full protection at nanomolar concentrations in a well-defined model of neur
132 also under the control of QS) by over 80% at nanomolar concentrations in a wild-type S. aureus group-
133 imetric detection of synthetic cathinones at nanomolar concentrations in biological samples is achiev
134 SD-36 induces rapid STAT3 degradation at low nanomolar concentrations in cells and fails to degrade o
137 ate AHR-mediated transcription, even at high nanomolar concentrations in human hepatoma (HepG2)- and
139 and mitotic inhibitors with potencies at low nanomolar concentrations in multiple tumor cell lines.
140 ety of marine biota and has been detected at nanomolar concentrations in oceanic surface waters.
141 amoxifen and its metabolites were present in nanomolar concentrations in plasma and muscles,suggestin
142 that selectively activates the human AHR at nanomolar concentrations in primary human hepatocytes, r
143 liferation of several lymphoma cell lines at nanomolar concentrations in the absence of a crosslinkin
144 single sulfation step and is present at low nanomolar concentrations in the central nervous system.
146 Dasatinib inhibited Src kinase activity at nanomolar concentrations in these sarcoma cell lines.
147 s: it (i) detects proteins from attomolar to nanomolar concentrations in unprocessed biological sampl
150 In addition, some of these secreted IA, at nanomolar concentrations, inhibited infection of primary
152 detection of lead, zinc, and cadmium ions at nanomolar concentration is possible in short time, thank
153 ethanol in aqueous environmental matrixes at nanomolar concentrations is presented and compared to an
154 sensing system able to detect Hg(2+) at low nanomolar concentrations is reported that operates throu
155 ermal and requires only nanoliter volumes at nanomolar concentrations, it will allow for the fast scr
156 ocampal long-term potentiation, whereas high nanomolar concentrations lead to the well established re
157 ime binding events of the target molecule at nanomolar concentration levels and could be potentially
159 In this study we show that Ag(+) at low nanomolar concentrations (<10 nM) strongly inhibits the
164 of antinociceptive agents, is blocked by low nanomolar concentrations of (-)-tetrodotoxin(TTX) but no
167 ecreased proliferation and survival with low nanomolar concentrations of 5-aza-CdR is associated with
169 human airway epithelial cultures respond to nanomolar concentrations of ACT when applied to basolate
171 ge-dependent anion channel, we revealed that nanomolar concentrations of amyloid beta-peptide increas
172 in is applicable to any living tissue, where nanomolar concentrations of ATP play a critical role in
173 gh signal-to-background ratio obtained using nanomolar concentrations of BARAC obviated the need for
174 rolimus in the treatment of HGG cells at low nanomolar concentrations of both agents, with a reductio
175 milar to many other FPR2 agonistic peptides, nanomolar concentrations of both PSMalpha2 and PSMalpha3
177 ment of cancer cells with micromolar but not nanomolar concentrations of CCI-779 caused a marked decl
179 ate Alexandrium minutum responds to pico- to nanomolar concentrations of copepodamides with up to a 2
182 tor binding assay allowed rapid detection of nanomolar concentrations of cyclic imine neurotoxins dir
191 range (1.6 nM to 1 muM) and was sensitive to nanomolar concentrations of glucose with a very low limi
192 actions; radical activities corresponding to nanomolar concentrations of H(2)O(2) could be detected.
194 he Isd system are required for growth on low nanomolar concentrations of hemoglobin as a sole source
196 pyrithione (ZnPy), we demonstrate that low, nanomolar concentrations of intracellular Zn(2+) ([Zn(2+
198 amp recordings in brain slices to reveal how nanomolar concentrations of KYNA alter synaptic transmis
199 pores to sense the activity of picomolar to nanomolar concentrations of membrane-active enzymes with
201 an wild-type plants to growth retardation by nanomolar concentrations of MTX, and this is associated
206 ingly, using competitive ELISA, we found low nanomolar concentrations of Pepcans in human plasma and
208 o endogenous ligands but can be activated by nanomolar concentrations of pharmacologically inert, dru
210 e to mature human spermatozoa, we found that nanomolar concentrations of progesterone dramatically po
211 QD PL caused by the activity of picomolar to nanomolar concentrations of protease were detected as ch
212 r membrane (optoporation) in order to inject nanomolar concentrations of rhodamine phalloidin (an imp
213 d for the fluorescence-based quantitation of nanomolar concentrations of ribonucleoside diphosphates
215 kemia cells with constitutive Wnt activation nanomolar concentrations of salinomycin down-regulated t
218 bo1 and Robo2) and that CAD cells respond to nanomolar concentrations of Slit2 by markedly decelerati
219 strong inhibition of osteoblast viability by nanomolar concentrations of sphingosine, but not of cera
220 ults show that the organic exudate generates nanomolar concentrations of superoxide and hydrogen pero
221 d that SK channels can be fully activated by nanomolar concentrations of Tb(3+), indicating an appare
222 ding of CA200645 to tauD3 was antagonized by nanomolar concentrations of the A3 antagonist MRS 1220,
225 at an excited state quenching is possible at nanomolar concentrations of the proteins, while the disa
227 pe plants when incubated in media containing nanomolar concentrations of this antifolate, and vacuola
229 The approach allows the quantification of nanomolar concentrations of thrombin, and provides assoc
230 rium inhibition in the prolonged presence of nanomolar concentrations of tkP3BzPB was nearly 100%.
233 roteins, which was prevented by inclusion of nanomolar concentrations of unlabeled NAADP or 5N(3)-NAA
235 urthermore, exposure of endothelial cells to nanomolar concentrations of vorapaxar induces endothelia
237 that in MT1/MT2 cultures, physiological (low nanomolar) concentrations of melatonin decrease the acti
238 Here we present in vivo evidence that low (nanomolar) concentrations of RGD-mimetic alpha(v)beta(3)
239 ubiquitin and the ESCRT-III subunit VPS20 at nanomolar concentrations on membranes with the same stoi
241 E2) biomaterial scaffolds that release E2 at nanomolar concentrations over the course of 1-10 years v
243 owed for the study of interacting species at nanomolar concentrations providing information unattaina
244 excellent antiproliferative activity in the nanomolar concentration range against HCT116 cancer cell
245 es with Ki and IC50 values in the micromolar/nanomolar concentration range and further substantiated
246 r-Ser-Pro-Gly-Ser-Ser with affinities in the nanomolar concentration range and prefers this sequence
247 erved that PlaB was most active in the lower nanomolar concentration range but not at or only at a lo
248 of histamine in the physiologically relevant nanomolar concentration range is possible in neutral and
249 diastereomers was possible down to the lower nanomolar concentration range, and enantiomeric ratios c
250 ALP activity with the enzyme present in the nanomolar concentration range, operating either in an en
251 monstrated efficient detection of IgG in the nanomolar concentration range, similar to the alkylthiol
261 ese self-assembled capsules at the micro- to nanomolar concentration ranges that are not accessible b
263 ssays reveal that DEHP activates CAR2 at low nanomolar concentrations, results further supported by a
265 criptional activation in the L701A AR at low nanomolar concentrations similar to the T877A mutant.
267 (FITC) gave fluorescent probes that bound at nanomolar concentrations specifically to human equilibra
269 on of [(3)H]DAMGO binding at subnanomolar to nanomolar concentrations, suggesting that these analogue
270 at is endowed with an inhibitory activity at nanomolar concentrations, suitable pharmacokinetic prope
271 nes inhibited NQO2 activity in K562 cells at nanomolar concentrations that did not inhibit NQO1 and w
275 ) bind the chemokines with high affinity (at nanomolar concentration), thereby blocking receptor bind
276 ity of five primary neuroblastoma samples in nanomolar concentrations thought to be achievable in hum
277 ctivate human and mouse FPR1 and FPR2 at low nanomolar concentrations, thus establishing FPR1 and FPR
278 One of the developed dyes could be used at a nanomolar concentration to selectively stain lipid dropl
279 endent manner, from cell-cycle arrest at low nanomolar concentrations to cell death at concentrations
281 ymene or biphenyl) are potently cytotoxic at nanomolar concentrations toward a panel of human cancer
282 ncluding a broad pH range (3-13), storage at nanomolar concentration, under ambient conditions, in 10
283 have been synthesized that inhibit, with low nanomolar concentrations, (V600E)BRAF, its downstream si
285 orylated and total proteins, in picomolar to nanomolar concentrations, were interpolated from standar
286 able to inhibit tumor cell proliferation at nanomolar concentrations when tested against the full NC
287 he number of newly generated neurons only at nanomolar concentrations where the MOR component is pred
288 ition 7, were significantly cytotoxic at low nanomolar concentrations whereas most were much less pot
289 apoptosis in highly invasive tumor cells at nanomolar concentrations which was executed by the mitoc
290 inhibition by ferrous ions is documented at nanomolar concentrations, which is a potentially physiol
291 h of MM lines and primary myeloma samples at nanomolar concentrations while having less of an effect
292 1, JAK2, and tyrosine kinase 2 (TYK2) at low nanomolar concentrations, with few additional targets.
293 compounds upregulated NMD-targeted mRNAs at nanomolar concentrations, with minimal toxicity in cell-
294 6 induced degradation of BET proteins at low nanomolar concentrations within 1 hour of exposure, resu
296 cell envelope of intact Bacillus subtilis to nanomolar concentration without any special sample prepa
297 mpound encountered in this study and acts at nanomolar concentrations without affecting tumor microen
299 eficial effects in globin gene expression at nanomolar concentrations without perturbing erythroid ex
300 nt ligation of peptide fragments down to low nanomolar concentrations, without resorting to solubilit