ライフサイエンスコーパス: natural course

1 the sample (i.e., we can compare against the natural course).

2 the simulated outcome under no intervention (natural course).

3 nderstanding of the disorder's incidence and natural course.

4 reement between the observed and model-based natural courses.

5 e then estimated an effect that compared the natural course against the scenario in which participant

6 rge, unselected, birth cohort studies on the natural course and comorbidities of rhinitis in children

7 f retinal pigment epithelium origin, and the natural course and functional changes are described.

8 Both MMG and PROSE changed the natural course and helped in preserving and improving vi

9 agement and definitive therapies affects the natural course and hence morbidity and mortality.

10 These results contribute to defining the natural course and prognosis of decompensated HCV-relate

11 The natural course and prognosis of medium drusen and risk f

12 thma phenotype and little is known about its natural course and prognosis.

13 revalence of e-CHB in Asia and to assess its natural course and response to treatment.

14 The natural course and treatment strategies for asymptomatic

15 effect on human immunodeficiency virus (HIV) natural course, and HBV vaccination is less effective in

16 ntly accumulating data on clinical features, natural course, and treatment outcome in adult arteriove

17 , clinical manifestations, imaging features, natural course, and visual prognosis.

18 Here, we demonstrate how the natural course can be estimated and used in causal analy

19 ic models, but whether one should estimate a natural course contrast depends on the underlying resear

20 It is good practice to estimate the natural course for model validation when using parametri

21 treatment of choroidal melanoma early in its natural course is critical to providing the patient with

22 in arteriovenous malformations (AVMs) in the natural course is essential for assessing risks and bene

23 Understanding the natural course is needed for optimal trial design.

24 ound during cholecystectomy suggest that the natural course might not be as favorable as earlier sugg

25 Instead, this natural course occurs only in a smaller proportion of pa

26 tion in clinical science is how to study the natural course of a chronic disease from inception to en

27 ategies aimed to break, stop, or reverse the natural course of a chronic invalidating disease.

28 tool to extract reliable information on the natural course of a disease.

29 potential confounding effects related to the natural course of a psychotic illness is challenging.

30 This case report sheds light on the unknown natural course of a solitary idiopathic choroiditis (foc

31 The natural course of a vortex vein varix, though not well u

32 (NK) cells play an important role during the natural course of acute HCV, we assessed the NK cell com

33 Our data show that the natural course of AD can be divided into subgroups that

34 So far, studies investigating the natural course of AD during adolescence and adulthood ar

35 aim of the present study was to predict the natural course of AD using clinical parameters and serum

36 remor fall between those associated with the natural course of aging and the more pronounced rates ob

37 Until now, evidence on the natural course of AK including spontaneous regression is

38 ms are the first symptoms to occur, that the natural course of alcohol and substance abuse parallels

39 ective and safe treatment, that modifies the natural course of allergic disease and induces long-term

40 ic asthma and has the potential to alter the natural course of allergic disease.

41 ) serial imaging in same animal to determine natural course of angiogenesis (n = 4), and (d) dose res

42 The natural course of angiogenesis and its inhibition could

43 ry organ dysfunction, and outcome during the natural course of ARDS and in response to prolonged meth

44 These analyses offer insight into the natural course of asthma activity that may help improve

45 These data shed light on the natural course of beta-cell function; over 5.2 years, me

46 erm, follow-up study was to characterize the natural course of changes in blood speed and blood flow

47 The natural course of childhood asthma and allergy is comple

48 This study aimed to investigate the natural course of chronic HBV infection in children with

49 The natural course of chronic HBV infection is now perceived

50 The natural course of chronic hepatitis B (CHB) infection an

51 The natural course of chronic myelomonocytic leukemia (CMML)

52 the control SIVmac-infected animals showed a natural course of chronic SIV infection.

53 methods in CKD; improve understanding of the natural course of CKD; assess and implement established

54 s are evident, but there are few data on the natural course of classical and nonclassical disease in

55 induced diabetic rat model, we evaluated the natural course of DCM over a period of 1 year by serial

56 In addition, we examined the natural course of degeneration and cavitation at the sit

57 Although the natural course of DFSP in the setting of ADA-SCID is unk

58 phenotyping may be useful in determining the natural course of diabetic neuropathy to identify patien

59 l3 of 27 treatment-naive patients during the natural course of disease (median 4, range 3-6 years).

60 ion, the role of ICS therapy in altering the natural course of disease in children with emerging asth

61 The natural course of disease ranges from subclinical epithe

62 CD4(+) memory T cells that occurs during the natural course of disease, and glomerular infiltration o

63 reatment that can reduce symptoms, alter the natural course of disease, and induce long-term clinical

64 ts comprise three tumour types with distinct natural course of disease, response to treatment and out

65 yping is without doubt useful to predict the natural course of disease, to determine pharmacotherapy

66 ients and its occurrence seems to change the natural course of disease.

67 cused on the prediction of and effect on the natural course of disease.

68 otyped patients with diabetes elucidates the natural course of DSPN.

69 During the natural course of EAE, B7-2 expression in the CNS correl

70 We sought to describe the natural course of egg allergy and to identify early prog

71 tervention with incidence under the observed natural course of exposure; results that may be more tan

72 To describe the natural course of Fabry disease stratified by sex and ph

73 ribe and evaluate differential diagnoses and natural course of fatigue five years after giardiasis am

74 he study context provided information on the natural course of findings that were not referred.

75 Over the past decades, it is noted that the natural course of HBV in persons infected are taking a w

76 vides an ideal population to investigate the natural course of HCV infection in a large, homogenous c

77 The natural course of HCV infection remains controversial.

78 examined the role of human cytokines in the natural course of hepatitis B surface Ag (HBsAg) serocon

79 ) cells play a role in the early control and natural course of hepatitis C virus (HCV) infection.

80 acebo group, indicating little impact on the natural course of HF.

81 ctivation represent key differences from the natural course of HIV infection in humans.

82 terventions that interrupt this stage in the natural course of HIV infection.

83 role for these molecules in controlling the natural course of HIV infection.

84 The natural course of HIV-1 infection is characterized by a

85 s underlying the host response and the slow, natural course of HIV-1 infection.

86 Virus-specific immune responses in the natural course of HIV-1C infection were analyzed in the

87 Throughout the natural course of human immunodeficiency virus (HIV) inf

88 VZV pathogenesis that are important for the natural course of human infection.

89 ng to a treat-to-target paradigm affects the natural course of IBD remains unclear, leading to the ne

90 During the natural course of idiopathic ERM, deformation of the out

91 We studied the natural course of idiopathic VMT in 46 eyes (46 patients

92 347 Dutch patients with HIV to calculate the natural course of illness, we developed a lifetime Marko

93 cell receptors (TCR) that develop during the natural course of immune responses may not allow suffici

94 between HIV and the immune system during the natural course of infection and in the context of differ

95 s C virus (HCV) quasispecies dynamics in the natural course of infection are rare owing to difficulti

96 ing microbial community structure during the natural course of infection in humans.

97 HIV replication occurs throughout the natural course of infection in secondary lymphoid tissue

98 opathic effects, a process reflective of its natural course of infection in the lungs.

99 onary trajectory of this pathogen during the natural course of infection within individual patients.

100 Thus, in a natural course of infection, RBCs are likely exploited f

101 y phase of HIV-1 infection may influence the natural course of infection.

102 umococci into the middle ear, similar to the natural course of infection.

103 ized by the immune system in vivo during the natural course of infection.

104 senses and that induces virulence during the natural course of infection.

105 he importance of preconception planning, the natural course of intraocular pressure during pregnancy,

106 dge is limited regarding the development and natural course of joint-related jaw dysfunction and its

107 ved vertebrate, were used to investigate the natural course of kidney aging.

108 tomach and, therefore, fail to replicate the natural course of L. monocytogenes infection.

109 To determine the natural course of LAR more precisely, this study is in p

110 de a neuroprotective effect and to alter the natural course of levodopa-treated Parkinson's disease (

111 Although these therapies have changed the natural course of many cancers, several may also lead to

112 Furthermore, these data suggest that the natural course of metastasis is selectively relaxed rela

113 Defining the natural course of MetS in a spontaneous animal model of

114 During the natural course of multiple sclerosis (MS), the brain is

115 This study showed that the natural course of myelopathy in CM-I-syringomyelia varie

116 We determined the natural course of NAFLD (liver fat [LFAT]) and type 2 di

117 The natural course of nAMD in both eyes needs to be consider

118 Describing the natural course of neovascular age-related macular degene

119 re of first-line treatments or to modify the natural course of OA disease.

120 consequence of aging but occur early in the natural course of obesity.

121 We aimed to describe the natural course of orofacial pain in a general population

122 ion against different L1 isoforms during the natural course of papillomavirus infection.

123 whether responses to placebo differ from the natural course of physiological changes that occur witho

124 Eculizumab dramatically alters the natural course of PNH, reducing symptoms and disease com

125 jective of this study was to investigate the natural course of pollen-induced AR (pollen-AR) over 20

126 ship between treatment interventions and the natural course of PTSD.

127 Published retrospective data on the natural course of PVD, retinal tears, and lattice degene

128 bout FAZ area and VA correlations during the natural course of retinal vascular diseases and followin

129 r understanding of susceptibility to and the natural course of SARS-CoV-2 infection.

130 -specific CD8(+) T cell responses during the natural course of SARS-CoV-2 infection.

131 d unknown/nonmalignant etiologies) and their natural course of SE.

132 nant comparator group to provide data on the natural course of seizure frequency in both groups.

133 IL-27 (p28/EBI3) have been implicated in the natural course of sepsis, whereas the molecular mechanis

134 ect is important for its implications in the natural course of SLE, because most if not all of the cl

135 ce of control participants, and the variable natural course of some types of uveitis.

136 Although the natural course of stress-induced cardiomyopathy is resol

137 e long-term studies are needed to assess the natural course of the autograft.

138 years varied by cause, which may reflect the natural course of the chronic disease and illustrates th

139 This finding may be useful in charting the natural course of the disease and in defining a therapeu

140 l as noninvasive, temporal monitoring of the natural course of the disease and response to therapy.

141 nclude early metastatic dissemination in the natural course of the disease and the near guaranteed em

142 sence of LHEP does not seem to influence the natural course of the disease and the response to surger

143 er-risk disease, the concept of altering the natural course of the disease in lower-risk MDS, and the

144 attributed to placebo effect may reflect the natural course of the disease itself.

145 zed along with publications reporting on the natural course of the disease or studies reporting on ou

146 cant myopic maculopathy progression over the natural course of the disease, compromising the BCVA as

147 peutic interventions significantly alter the natural course of the disease.

148 atment has proven effective in modifying the natural course of the disease.

149 unotherapy was followed as a control for the natural course of the disease.

150 hether antioxidant therapy may influence the natural course of the disease.

151 measurement time points, variability and the natural course of the disease.

152 able outcome and without comparison with the natural course of the disease.

153 of symptoms improvement and evolution of the natural course of the disease.

154 has focused on the early signs of PC and the natural course of the disease.

155 ansfusion needs and potentially to alter the natural course of the disease.

156 s but also endomysial T cells and alters the natural course of the disease.

157 eir treating clinicians include: What is the natural course of the disease?

158 lera prevalence in early 2011 is part of the natural course of the epidemic, and should not be interp

159 p antibody neutralization breadth during the natural course of the infection, often linked to chronic

160 chanism could be involved in CD4 loss in the natural course of the infection.

161 mechanisms and increasing recognition of the natural course of the spondyloarthropathies are leading

162 epared to educate parents about the expected natural course of their child's illness and the likeliho

163 remission might be the best way to alter the natural course of these diseases by preventing disabilit

164 egligible, especially in terms of the benign natural course of these lesions.

165 nducted to gain further understanding of the natural course of this common childhood condition.

166 the MRSS was similar to that expected in the natural course of this disease.

167 However, the natural course of this important patient subgroup remain

168 vides a research opportunity to evaluate the natural course of this neurological finding.

169 f benzene by a tungsten complex disrupts the natural course of this reaction sequence, allowing for F

170 This might alter the natural course of tissue remodeling in TAO.

171 cells and tumor epithelium occurs during the natural course of tumorigenesis.

172 involvement of the exocrine pancreas in the natural course of type 1 diabetes that will require cons

173 This study showed that the natural course of unruptured cerebral aneurysms varies a

174 Large variabilities in phenotype and natural course of XLRS were seen in this study.

175 f CD4+ T cell functionality during different natural courses of infection, with the notable implicati

176 Furthermore, the 'natural' course of recovery correlates of postconcussion

177 information on clinical relevance, including natural course, over a period of up to 9 years.

178 If the disorder was left to take its natural course, patients on average had a total of 3 QAL

179 However, it is unclear how to evaluate natural course performance and whether other variables s

180 etric model sets and qualitatively assessing natural course performance for all time-varying variable

181 We recommend reporting natural course performance for all time-varying variable

182 vational analyses of the UAW-GM cohort, good natural course performance of the outcome does not guara

183 t common cause of liver disease, and yet the natural course remains unclear.

184 induced CNV was highly reproducible, and its natural course seems to be ideal for evaluating therapeu

185 maculopathy can present with a more variable natural course than previously described.

186 aoperative measures were taken (representing natural course), the risk for unfavorable outcomes was 2

187 To validate our models, we estimated the natural course using g-computation and then compared tha

188 ly thought to be an indolent tumour, but its natural course was not thoroughly investigated until the

189 sociated with substantial variability in its natural course within and between affected families.