ライフサイエンスコーパス: neoangiogenesis

1 tasis initiation with immune suppression and neoangiogenesis.

2 scular endothelial growth factor protein and neoangiogenesis.

3 raft growth in mice while markedly impairing neoangiogenesis.

4 l components of the earliest phases of tumor neoangiogenesis.

5 al neoplasia, stimulating cell migration and neoangiogenesis.

6 ment of VEGF in MDSC transplantation-induced neoangiogenesis.

7 Ps may be clinically effective in augmenting neoangiogenesis.

8 how bone marrow derived cells contribute to neoangiogenesis.

9 entify PML as a novel suppressor of mTOR and neoangiogenesis.

10 ciated with an osteoblast bone formation and neoangiogenesis.

11 ith the expression of osteoblast markers and neoangiogenesis.

12 earch to identify factors that support tumor neoangiogenesis.

13 activity constitutes a barrier to effective neoangiogenesis.

14 cancer progression, presumably by preventing neoangiogenesis.

15 d inflammation was associated with increased neoangiogenesis.

16 Tumor growth requires neoangiogenesis.

17 tions in the hosts, including stimulation of neoangiogenesis.

18 of NO formation resulted in reduced retinal neoangiogenesis.

19 ed by hypoxia-inducible factor signaling and neoangiogenesis.

20 retion, extracellular matrix stiffening, and neoangiogenesis.

21 ne tumor (pNET) model commonly used to study neoangiogenesis.

22 endowed with protumoral activities, such as neoangiogenesis.

23 ng of AMCs into areas of MM tumor growth and neoangiogenesis.

24 proliferation and invasiveness coupled with neoangiogenesis.

25 stromal endothelial cells that mediate tumor neoangiogenesis.

26 g to the degree of vascular inflammation and neoangiogenesis.

27 solid tumors one had to target the inherent neoangiogenesis.

28 sites of ischemic injury where they promote neoangiogenesis.

29 ritical role in vascular tone regulation and neoangiogenesis.

30 nic liver diseases associated with increased neoangiogenesis.

31 emained mostly intact and showed very little neoangiogenesis.

32 on of Angiopoietin-1 in pericytes to enhance neoangiogenesis.

33 n, result in vision loss because of aberrant neoangiogenesis.

34 ial progenitor cells in the process of tumor neoangiogenesis.

35 ecreased beta8 expression leads to defective neoangiogenesis.

36 its and extravasated red blood cells, making neoangiogenesis a key component of the tumor.

37 Wound healing is facilitated by neoangiogenesis, a complex process that is essential to

38 RII) are the predominant regulators of tumor neoangiogenesis, a key element for tumor growth and prog

39 Artery tertiary lymphoid organs show marked neoangiogenesis, aberrant lymphangiogenesis, and extensi

40 thelial growth factor (VEGF) expression, and neoangiogenesis after retinal hypoxia.

41 on, exhibit a decrease in glioma volumes and neoangiogenesis and an increase in antitumorigenic GAM i

42 en considering associations between hypoxia, neoangiogenesis and antitumor activity.

43 oster disease development by promoting tumor neoangiogenesis and by enhancing cancer metastasis.

44 alysis of brain tumors including the rate of neoangiogenesis and cellularity.

45 tion of Cxcl9 led to a strong attenuation of neoangiogenesis and experimental liver fibrosis in vivo.

46 ner, thus favoring tumor growth by promoting neoangiogenesis and immunosuppression.

47 c-Cbl deletion was associated with enhanced neoangiogenesis and increased expression of vascular end

48 (KSHV) and is characterized by uncontrolled neoangiogenesis and inflammation.

49 oproteinase (MMP)-2 has been associated with neoangiogenesis and it has been proposed that the levels

50 tumor microenvironment severely compromised neoangiogenesis and lymphangiogenesis during pancreatic

51 the in vivo effects of the matrix protein on neoangiogenesis and lymphoid organization.

52 onstitute a favorable environment to support neoangiogenesis and may explain why vascular insults syn

53 rmalities in the pancreas included fibrosis, neoangiogenesis and mild macrophage infiltration, and th

54 ees of cellularity, mitoses, hypoxia-induced neoangiogenesis and necrosis, features that characterize

55 type), which is accompanied by inflammation, neoangiogenesis and neoinnervation, resulting in shoulde

56 rks may form downstream of mutant effects on neoangiogenesis and neuronal survival.

57 factors did not have any benefit in terms of neoangiogenesis and perfusion and had minimal effect on

58 coordinates stemness with immune evasion and neoangiogenesis and point to the potential clinical util

59 Lactate itself also stimulated neoangiogenesis and prostate cancer cell migration, whic

60 tch receptor signaling is required for tumor neoangiogenesis and provides a new target for tumor ther

61 dent remodeling of the myofibers may promote neoangiogenesis and restoration of blood perfusion in sk

62 ransmural inflammation induces microvascular neoangiogenesis and results in lumen-occlusive intimal h

63 Neoangiogenesis and STAT3 hyperactivation are known to b

64 of COUP-TFII in adults severely compromised neoangiogenesis and suppressed tumor growth in xenograft

65 ly following treatment, suggesting increased neoangiogenesis and T-cell infiltration upon treatment o

66 uggest that JNK1 plays a key role in retinal neoangiogenesis and that it represents a new pharmacolog

67 iseased mouse and human arteries in areas of neoangiogenesis and that these cells constitute a main c

68 UM resolved typical features of neoangiogenesis and tumor cell invasion with a spatial r

69 Neoangiogenesis and vascular injury are observed in IBD

70 Concomitantly, the subsequent neoangiogenesis and vascular leakage are prevented by TS

71 r3(-/-) mice was strongly linked to enhanced neoangiogenesis and VEGF/VEGFR2 expression compared with

72 an important protumorigenic role by favoring neoangiogenesis and/or by suppressing antitumor immune r

73 ltered production of inflammatory cytokines, neoangiogenesis, and autoreactive T lymphocytes have all

74 A/histone epigenetic complex, antiapoptosis, neoangiogenesis, and immune modulation.

75 ression through induction of tumor invasion, neoangiogenesis, and immunosuppression.

76 tegrin beta3 is critical for tumor invasion, neoangiogenesis, and inflammation, making it a promising

77 e alternative activation, immunosuppression, neoangiogenesis, and melanoma tumor outgrowth.

78 several effects including reducing fibrosis, neoangiogenesis, and neomyogenesis.

79 rrow stromal alterations marked by fibrosis, neoangiogenesis, and osteomyelosclerosis.

80 ion and the functional role of EPCs in tumor neoangiogenesis are controversial.

81 l mechanism by which neurofibromin regulates neoangiogenesis are not known.

82 (+) effector T cells developed microvascular neoangiogenesis as well as hyperplasia of the intimal la

83 This vascular pattern is not suggestive for neoangiogenesis, as arteriovenous shunts from malignant

84 The ability to undergo neoangiogenesis, as measured in a window-chamber model,

85 proliferation at early stages and promoting neoangiogenesis at late stages of progression.

86 etastasis, concomitant with a suppression of neoangiogenesis at secondary sites, while leaving primar

87 nhibitors p130 and p27 show defects in tumor neoangiogenesis, both in xenografts and spontaneously ar

88 ssels, suggesting that VEGF is essential for neoangiogenesis but not survival of mature vessels in th

89 novial hypertrophy, macrophage infiltration, neoangiogenesis, cartilage degeneration, and chondrocyte

90 is ameliorative effect is linked to enhanced neoangiogenesis (CD31 staining and microfil perfusion) b

91 Both inflammation and neoangiogenesis contribute to abdominal aortic aneurysm

92 espiration in vascular endothelial cells for neoangiogenesis during development, tissue repair and ca

93 ating that VEGF is essential for endometrial neoangiogenesis during postmenstrual/postpartum repair.

94 h as macrophages, have been shown to promote neoangiogenesis during tumor growth and wound healing.

95 ation of these systems may minimise both the neoangiogenesis essential for tumour growth and associat

96 ed to the ability of breast tumors to induce neoangiogenesis, even in the face of cytotoxic chemother

97 l, we determined that heart regeneration and neoangiogenesis following MI depends on neonatal macroph

98 rived growth factors and cytokines stimulate neoangiogenesis from surrounding capillaries to support

99 e show that venous endothelial cells express neoangiogenesis gene signatures and show increased proli

100 Tumor-associated neoangiogenesis has recently become a suitable target fo

101 b, an inhibitor of key molecules involved in neoangiogenesis, has an established role in the treatmen

102 Increased vascularity and neoangiogenesis have been implicated in the progression

103 ritis patients with and without up-regulated neoangiogenesis identified interferon-gamma and vascular

104 induce impressive reversal of skin fibrosis, neoangiogenesis, improved functionality and quality of l

105 plays critical roles in tumor metastasis and neoangiogenesis in a variety of cancers.

106 Histology demonstrated increased neoangiogenesis in both treatment groups.

107 ted at the KDR, one of the key regulators of neoangiogenesis in cancer.

108 We therefore investigated neoangiogenesis in carbon tetrachloride (CCl(4))-induced

109 ibited the sprouts of mouse aortic rings and neoangiogenesis in chick embryo chorioallantoic membrane

110 that venous endothelial cells contribute to neoangiogenesis in demyelinating neuroinflammatory condi

111 To study the regulation of neoangiogenesis in giant cell arteritis, temporal arteri

112 netic resonance and optical toolkit to study neoangiogenesis in glioma models.

113 sporadic renal carcinomas, and it stimulates neoangiogenesis in growing solid tumors.

114 mediated endothelial cell proliferation and neoangiogenesis in human Matrigel and placental angiogen

115 from hypoxia-treated tumor cells results in neoangiogenesis in human umbilical vein endothelial cell

116 Sustained VEGF delivery alone led to neoangiogenesis in ischemic limbs, with complete return

117 in parameters, EPC numbers and function, and neoangiogenesis in lupus-prone mice, independent of dise

118 ila, a process reminiscent of cancer-induced neoangiogenesis in mammals.

119 P-DKO mice were more effective in supporting neoangiogenesis in Matrigel plugs.

120 s studies of APN-null mice revealed impaired neoangiogenesis in model systems without cancer cells an

121 ings show that the A2 system enables retinal neoangiogenesis in OIR by enhancing perivascular activat

122 otherwise active in adult hearts and during neoangiogenesis in other adult settings.

123 ility is accompanied by reduced pathological neoangiogenesis in oxygen-induced retinopathy, similarly

124 sponse, and to accelerate tissue healing and neoangiogenesis in the face of noxious stimuli.

125 to improve myocardial perfusion by enhancing neoangiogenesis in the failing heart.

126 be attributed, at least in part, to enhanced neoangiogenesis in the infarcted region via upregulation

127 erleukin-6, infiltration of macrophages, and neoangiogenesis in the synovium following hemarthrosis.

128 integrin resulted in a dramatic increase in neoangiogenesis in the wound microenvironment.

129 es into endothelial cells that contribute to neoangiogenesis in tumors.

130 mature endothelial cells, and contribute to neoangiogenesis in vivo during tumor angiogenesis and wo

131 ated levels of endoglin (CD105), a marker of neoangiogenesis, in BSIII-IV, coinciding with altered ex

132 to fibronectin (Fn) during embryogenesis and neoangiogenesis, including many cancers.

133 lated by sera of patients with TAK supported neoangiogenesis (increased human umbilic vein endothelia

134 lated by sera of patients with TAK supported neoangiogenesis (increased human umbilic vein endothelia

135 ch co-opts vessels in a VEGF-independent and neoangiogenesis-independent manner, was upregulated in n

136 cific and hypoxia-inducible VEGF expression, neoangiogenesis, infarct-size reduction, and cardiac fun

137 inantly of vascular endothelial cell origin, neoangiogenesis, inflammatory cell infiltration, and ede

138 ve response to injury, leading to intramural neoangiogenesis, intimal hyperplasia, and luminal occlus

139 Neoangiogenesis involves both bone marrow-derived myelom

140 Neoangiogenesis is a pivotal therapeutic target in gliob

141 Neoangiogenesis is an important pathophysiological featu

142 et for treatment of diseases where excessive neoangiogenesis is the underlying pathology.

143 uitously expressed TPCs include VEGF-induced neoangiogenesis, LDL-cholesterol trafficking and degrada

144 Inhibition of Tie2 resulted in impaired neoangiogenesis, leading to a delay in hematopoietic rec

145 Using in vivo models of functional neoangiogenesis, LY2228820 dimesylate treatment reduced

146 VE-cadherin angiogenic complexes, levels of neoangiogenesis marker Endoglin, vascular density, and c

147 The growth and neoangiogenesis of P2X7-expressing tumors was blocked by

148 Neoangiogenesis or establishment of new blood supply is

149 lial progenitor cell (EPC) function, in vivo neoangiogenesis, plaque development, and occlusive throm

150 Induction of neoangiogenesis plays an important role in the pathogene

151 l progenitor cells (EPCs) may play a role in neoangiogenesis (postnatal vasculogenesis).

152 of HJD subjects, implicating hypoxia in the neoangiogenesis process.

153 Management of neoangiogenesis remains a high-value therapeutic goal.

154 HIF-1alpha pathway as a critical mediator of neoangiogenesis required for skeletal regeneration and s

155 The neoangiogenesis resulted in decreased apoptosis of hyper

156 ta also implicate DCs in regulation of tumor neoangiogenesis, suggesting a novel role of DCs in tumor

157 ERRgamma is a hypoxia-independent inducer of neoangiogenesis that can promote reparative revasculariz

158 antiangiogenic properties and the prominent neoangiogenesis that occurs in MMM.

159 enables the quantification of differences in neoangiogenesis that predict treatment efficacy.

160 owth by inducing newly formed blood vessels (neoangiogenesis) that sustain tumor cell viability and g

161 e we identify PML as a critical inhibitor of neoangiogenesis (the formation of new blood vessels) in

162 or and further production of VEGF to support neoangiogenesis, thereby favoring the development of the

163 F may provide a novel mechanism for inducing neoangiogenesis through both direct actions on local Trk

164 ic synergy correlates with the inhibition of neoangiogenesis through the downregulation of COX-2, iNO

165 vity to growth inhibitory signals, sustained neoangiogenesis, tissue invasiveness and migration capab

166 adation of extracellular matrix and promotes neoangiogenesis to facilitate tumor growth.

167 ting strategies that reduce inflammation and neoangiogenesis to reduce the incidence of restenosis.

168 cell proliferation, collagen deposition, and neoangiogenesis to the levels observed in control animal

169 In murine models of neoangiogenesis, UPI peptide increased VEGF-driven angio

170 cts that are preferentially expressed during neoangiogenesis: vascular endothelial growth factor rece

171 y stimulating podosome nucleation, motility, neoangiogenesis, vasculogenic mimicry, and osteoclastoge

172 ls play a key role in both tumorigenesis and neoangiogenesis via the production of matrix metalloprot

173 Neoangiogenesis was found in all valves with ossificatio

174 Neoangiogenesis was inhibited by SC-'236, which could ac

175 After AAV-VEGF inoculation, neoangiogenesis was observed in the ischemic heart model

176 n similar sized breast tumors, TAM and tumor neoangiogenesis was reduced.

177 In vivo, TIMs and neoangiogenesis were associated.

178 growth difference of tumor xenografts or in neoangiogenesis were found in beta3KOP mice, in contrast

179 erial inflammatory infiltrates and increased neoangiogenesis were observed in apoE(-/-) IFNAR(-/-) mi

180 non-ischemic ears or ischemic limbs induced neoangiogenesis, with a 2-fold increase in the capillary

181 cells of the newly formed capillaries during neoangiogenesis within malignant human brain tumors expr

182 Although neoangiogenesis within the infarcted tissue is an integr