ライフサイエンスコーパス: neocortex

1 ion processing across different parts of the neocortex.

2 s into stable generalized representations in neocortex.

3 retrograde tracer injections in the marmoset neocortex.

4 vidual brain regions' time-series across the neocortex.

5 entary information processing modules in the neocortex.

6 transferring information from hippocampus to neocortex.

7 aging methods in mouse primary somatosensory neocortex.

8 a representation of sensory features in the neocortex.

9 Ns was highly heterogeneous, particularly in neocortex.

10 ction relationships vary markedly across the neocortex.

11 ated aminopeptidase (EC 3.4.11.3) in the rat neocortex.

12 from neuronal activity patterns in mammalian neocortex.

13 e medial temporal lobe memory system and the neocortex.

14 ynapse and neuron formation in mouse sensory neocortex.

15 veral brain regions such as the thalamus and neocortex.

16 conditions, functional connectivity with the neocortex.

17 but it disturbs the laminar structure of the neocortex.

18 ch in turn causes gyrification of the distal neocortex.

19 l influence on preparatory activity in motor neocortex.

20 tionally knocked out (cKO) in the developing neocortex.

21 y alters inhibitory neurotransmission in the neocortex.

22 ocortical reactivation loop initiated by the neocortex.

23 d near the lateral ventricle in the prenatal neocortex.

24 y patterns have been prominently reported in neocortex.

25 in the corresponding functional area of the neocortex.

26 c extra-somatic glutamatergic input from the neocortex.

27 or the operation of neuronal circuits in the neocortex.

28 cells in temporal and prefrontal association neocortex.

29 upted neuronal migration in developing mouse neocortex.

30 transient firing in hippocampus and sensory neocortex.

31 control of sensory-evoked signal flow in the neocortex.

32 thalamus, medial temporal lobe and temporal neocortex.

33 ts of neurons in CA1 and CA3, but not in the neocortex.

34 y linked to decreased thickness of the human neocortex.

35 iatum and absent in the nonhuman African ape neocortex.

36 s cytoarchitectural changes in the embryonic neocortex.

37 ctional regulation of the motor areas of the neocortex.

38 of GABAergic inhibitory interneurons to the neocortex.

39 d regulate the maturation of the associative neocortex.

40 halamic nuclei that provide input to sensory neocortex.

41 atergic neurons of the telencephalon-derived neocortex.

42 pocampal memory of wake experiences into the neocortex.

43 ferentiation and migration in the developing neocortex.

44 mechanism, which pre-dates the evolution of neocortex.

45 tatory inputs originating from contralateral neocortex.

46 tion of dendritic signaling in the mammalian neocortex.

47 represent the major output cell type of the neocortex.

48 of GABAergic inhibitory interneurons to the neocortex.

49 ants of neuron subtype identity in the mouse neocortex.

50 ncreases BP proliferation in embryonic mouse neocortex.

51 daughter neuroblasts in the developing mouse neocortex.

52 ing throughout the hippocampal formation and neocortex.

53 laques based on certain key locations in the neocortex.

54 e-based taxonomy of cell types for mammalian neocortex.

55 te communication between the hippocampus and neocortex.

56 essed at a low level in the developing mouse neocortex.

57 hippocampus compared to temporal and frontal neocortex.

58 sembling the third trimester embryonic human neocortex.

59 nce was not observed in layers 4 or 5 of the neocortex.

60 defining inhibitory cell types in the mouse neocortex.

61 imately 33% of the total surface area of its neocortex.

62 o 78% of the total surface area of the human neocortex.

63 processing and information exchange with the neocortex.

64 red for BP proliferation in embryonic ferret neocortex.

65 it based in sensory areas in the back of the neocortex?

66 ) is a principal source of modulation of the neocortex [1-6] and is thought to regulate cognitive fun

67 andard methodology we previously used in the neocortex [20-22].

68 expressed genes (DEGs) (82), followed by the neocortex (76), hypothalamus (63), and cerebellum (26).

69 used to provide evidence for the role of the neocortex [9] and hippocampus [10, 11] in the schematiza

70 gration, abnormal distribution of CIN in the neocortex, a marked reduction of CINs expressing parvalb

71 In the mouse neocortex, a third of GABAergic interneurons are elimina

72 read reduction of amyloid plaques throughout neocortex after multi-sensory GENUS.

73 tal life and affect these fetal processes in neocortex, amygdala, hippocampus, striatum and cerebellu

74 stem cells recapitulates development of the neocortex, an area affected in both fragile X syndrome a

75 s and 19 bilateral thalamic nuclei) and both neocortex and brainstem ascending reticular activating s

76 holding for large and small synapses in the neocortex and brainstem.

77 By applying the same methods to the neocortex and cerebellum of the macaque monkey, we found

78 ordings from a variety of cells in the mouse neocortex and cerebellum.

79 erized the codependence of processing in the neocortex and cerebellum.

80 Direct infusion of 5-HT into the neocortex and chemogenetic activation of 5-HT neurons al

81 and median R2* values were calculated in the neocortex and cortical lobes, basal ganglia (BG), hippoc

82 tically stimulated cholinergic fibers in rat neocortex and find that ACh enhances excitability by red

83 etworks regulated by Foxp1 in the developing neocortex and found that such networks are enriched for

84 during neurogenesis in the developing human neocortex and highlight evolutionarily divergent mechani

85 Sleep oscillations in the neocortex and hippocampus are critical for the integrati

86 Most studies of SHANK3 in the neocortex and hippocampus have focused on disturbances i

87 s in astrocytes and neurons in slices of the neocortex and hippocampus of juvenile mice of both sexes

88 dulates oscillatory neuronal activity in the neocortex and hippocampus on a cycle-by-cycle basis.

89 escribed as a wall of inhibition between the neocortex and hippocampus.

90 multielectrode array recordings in the human neocortex and mesial temporal lobe during rhythmic onset

91 difficulty of the spatial tasks rests on the neocortex and on the limitations of working memory, not

92 um is a gray-matter structure that underlies neocortex and reciprocates connections with cortical and

93 nce that epileptic spasms can arise from the neocortex and reveal a previously unappreciated interpla

94 Termed the slow oscillation in the neocortex and sharp wave-ripples in the hippocampus, the

95 of the elastic stiffness of the injured rat neocortex and spinal cord at 1.5 and three weeks post-in

96 roliferation and migration to the overlaying neocortex and subsequent differentiation leading to lami

97 s to record electrophysiological activity in neocortex and thalamus during spasms.

98 rong bidirectional synaptic pathways linking neocortex and thalamus.

99 distinct laminar pattern in the adult mouse neocortex and that their cell type-specific expression d

100 widespread imaging abnormalities of the ALS neocortex and the accepted relationship between ALS and

101 By focusing on the neocortex and the cerebellar cortex, we demonstrate that

102 ck circuit that bidirectionally connects the neocortex and the cerebellum.

103 he main gateway for interactions between the neocortex and the hippocampus.

104 the claustrum, a nucleus located between the neocortex and the striatum, yet the functions of cortico

105 istinct cell populations in the hippocampus, neocortex, and cerebellum during development.

106 was reduced in the brainstem, basal ganglia, neocortex, and cerebellum within 13 dpi, indicating acut

107 ells in the developing human, but not mouse, neocortex, and inhibiting HTR2A receptors in human radia

108 asticity and learning in the mammalian adult neocortex, and provides insight into the function of bra

109 th the motor areas and nonmotor areas of the neocortex, and with the hypothalamus.

110 d layer-specific gadolinium retention in the neocortex (anterior cingulate cortex: mean gadolinium co

111 Diverse computations in the neocortex are aided by specialized GABAergic interneuron

112 ypes of excitatory neurons that populate the neocortex are born from apical progenitors located in th

113 Almost all areas of the neocortex are connected with the claustrum, a nucleus lo

114 As major efforts to model the neocortex are currently underway, it has become increasi

115 ical regions such as the hippocampus and the neocortex are defined by morphology, physiology, and gen

116 Neurons in sensory areas of the neocortex are known to represent information both about

117 tational formats of medial temporal lobe and neocortex are sufficient to determine both, memory conte

118 organization of primary sensory areas in the neocortex are well studied, what generates secondary cor

119 Astrocytes of the neocortex, as opposed to the hippocampus proper, also ex

120 on key evolutionary innovations shaping the neocortex at multiple levels of organization.

121 h early born and migrate into the developing neocortex at similar times, SST(+) cells are incorporate

122 elettes), the thalamus (barreloids), and the neocortex (barrels).

123 g choices occupied restricted regions in the neocortex, basal ganglia and midbrain.

124 pathology from the entorhinal cortex to the neocortex, before the clinical manifestations of Alzheim

125 CB1R-dependent manner in the hippocampus and neocortex brain regions.

126 by ~50% upon blocking NMDA receptors in the neocortex, but not hippocampus.

127 The amyloid effect was observed with tau in neocortex, but not with tau in entorhinal cortex, which

128 the connectivity of pyramidal neurons in the neocortex, but the functional relevance of this phenomen

129 rate-dependent effects in hippocampus versus neocortex, but those analyses were carried out separatel

130 trode array recordings from human and monkey neocortex by examining the spike-triggered LFP average (

131 irm that these findings also extend to human neocortex by quantifying interneuron axonal myelination

132 structural and functional maturation of the neocortex by refining the final number of cortical neuro

133 poral Scales of Cholinergic Signaling in the Neocortex, by Anita A.

134 Together, these data support a view of the neocortex-cerebellum circuit as a joint dynamic system b

135 mong the diverse interneuron subtypes in the neocortex, chandelier cells (ChCs) are the only populati

136 of attention are extensively studied in the neocortex; comparatively little is known about how subco

137 appeared to have stronger associations with neocortex compared to TDP-43.

138 subserved by parcellated areas of mammalian neocortex composed of repetitions of a canonical local c

139 The neocortex comprises multiple information processing stre

140 ytic energy reservoir in the hippocampus and neocortex, compromising long-term potentiation.

141 basal progenitors (BPs) per field in the OSB neocortex, consistent with an impairment of cortical neu

142 The neocortex conveys general representations of sensory eve

143 pocampus (aHIP) and middle gyrus of temporal neocortex (CX) were determined with western blots and co

144 ring the normal development of the mammalian neocortex depend on N-cadherin, including the radial mig

145 ep model of folding that pertains to primate neocortex development and evolution.

146 Neocortex development during embryonic stages requires t

147 Comparison of fetal neocortex development in long-tailed macaque and human r

148 Our data indicate that neocortex development in OSB fetuses is altered as early

149 This study provides novel data on neocortex development of human OSB fetuses.

150 To examine the effects of OSB on fetal neocortex development, we analyzed human fetuses of both

151 r results suggest that neuronal types in the neocortex do not always form discrete entities.

152 ry of concentric mammalian allo-, meso-, and neocortex domains.

153 In the primate neocortex, dozens of genes showed spatial expression gra

154 unction proteins occurs predominantly in the neocortex during Alzheimer's disease progression.

155 etabolism, and it is highly expressed in the neocortex during developmental stages.

156 on inducing information reinstatement in the neocortex during memory retrieval.

157 dial glia and interneurons in the developing neocortex during mid-gestation.

158 gates the architecture of ribosomes from the neocortex during neurogenesis, revealing Ebp1 as a high-

159 e gradually translocated from hippocampus to neocortex during non-rapid-eye-movement (NREM) sleep.

160 time subsequent information transfer to the neocortex during NREM sleep.

161 Inhibition of lateral neocortex during reconsolidation altered glucose consump

162 ppocampus can convey neuronal content to the neocortex during SPW-Rs.

163 formed in vivo two-photon calcium imaging in neocortex during temperature-induced seizures in male an

164 Purkinje cells and not detected in the mouse neocortex during the same developmental period, in which

165 We probed mouse neocortex during visual discrimination using a red-shift

166 The layers of the neocortex each have a unique anatomical connectivity and

167 not distinguished diverse cell types in the neocortex, even though different cell types possess dist

168 In a broader phylogenetic context, however, neocortex evolution in mammals, including humans, is rem

169 Neurons in the neocortex exhibit spontaneous spiking activity in the ab

170 Moreover, the analysis of infant human neocortex exhibiting lissencephaly, a developmental malf

171 ted developmental timeline compared with the neocortex, expanding the window of vulnerability to neur

172 Neocortex expansion is largely based on the proliferativ

173 recurrent synaptic connections in the adult neocortex following novel motor experience, and illumina

174 nclear how information is transferred to the neocortex for long-term engrams.

175 During sleep and awake rest, the neocortex generates large-scale slow-wave (SW) activity.

176 istent with this dominant view, cells in the neocortex gradually strengthen the selectivity for the m

177 Anatomical similarity across the neocortex has led to the common assumption that the circ

178 Investigations in the neocortex have revealed that the balance of excitatory a

179 s, studies of some regions (for example, the neocortex) have produced conflicting results.

180 ec(-1); AD, 30.2 sec(-1); P = .01) and total neocortex (HC, 17.0 sec(-1); AD, 17.4 sec(-1); P < .001)

181 ot observed in LRRK2 mutant neurons from the neocortex (hereafter, cortical neurons) or the hippocamp

182 aminar-expression profiles in the developing neocortex, highlighting their important roles in brain d

183 rences in glucose consumption in the lateral neocortex, hippocampus and amygdala in mice that underwe

184 Thus, the neocortex homolog cannot be found in the classical repti

185 the spatiotemporal development of the mouse neocortex, identifying underlying genetic programs that

186 ctional organization and connectivity of the neocortex in cortical areas that normally process visual

187 ncreasing evidence points to the role of the neocortex in encoding spatial information.

188 ring the tremendous overall expansion of the neocortex in human evolution, it has proven difficult to

189 y is among the first to describe its role in neocortex in relation to biophysical correlates of memor

190 rding over widespread regions of mice dorsal neocortex in relation to CA1 multiunit activity (MUA) an

191 ferent neuronal processing capacities of the neocortex in these mammals' orders.

192 rtical excitability were also found in human neocortex in vitro and in S1 of alert mice in vivo.

193 atches from layer 5 pyramidal neurons in rat neocortex, in physiological external calcium (1-2 mM).

194 motor cortex (M1) and in human postoperative neocortex, in vivo in mouse somatosensory cortex (S1), a

195 onal regulation of the nonmotor areas of the neocortex, including the prefrontal, associative, sensor

196 In the neocortex, inhibitory network formation occurs concurren

197 ical evidence on how the hippocampus and the neocortex interact dynamically when acquiring and then e

198 The sensory neocortex is a highly connected associative network that

199 Mammalian neocortex is a highly layered structure.

200 ary role in regulating the maturation of the neocortex is an increase in inhibitory neurotransmission

201 The mammalian neocortex is characterized by a variety of neuronal cell

202 Acetylcholine in the neocortex is critical for executive function [1-3].

203 -based strategy we observed that the lateral neocortex is functionally connected with the amygdala, w

204 The neocortex is functionally organized into layers.

205 aques and tau neurofibrillary tangles in the neocortex is linked to neural system failure and cogniti

206 phases of memory and found that the lateral neocortex is necessary for fear memory reconsolidation.

207 However, neocortex is not a feedforward architecture.

208 espread assumptions, we found that the human neocortex is not exceptionally large relative to other b

209 The mammalian neocortex is organized into layers distinguished by the

210 nd single-neuron firing in the multi-layered neocortex is poorly understood.

211 Most sensory information destined for the neocortex is relayed through the thalamus, where conside

212 e processes.SIGNIFICANCE STATEMENT While the neocortex is responsible for coordination of complex beh

213 An expansion of the cerebral neocortex is thought to be the foundation for the unique

214 STATEMENT In the human and nonhuman primate neocortex, layer 3 pyramidal neurons (L3PNs) differ sign

215 Throughout mammalian neocortex, layer 5 pyramidal (L5) cells project via the

216 hat conditional ablation of Kcnq2 from mouse neocortex leads to hyperexcitability of layer 2/3 (L2/3)

217 ctions during novel experiences, whereas the neocortex learns slowly through subsequent, off-line int

218 older species, the archer fish, which lacks neocortex-like cells.

219 zinc signaling.SIGNIFICANCE STATEMENT In the neocortex, limbic structures, and auditory brainstem, gl

220 In many brain areas, such as the neocortex, limbic structures, and auditory brainstem, sy

221 However, it remains unclear how neocortex maintains this asynchronous spiking regime.

222 mmals, the claustrum is directly adjacent to neocortex, making the definition of claustral boundaries

223 st that the decrease in BP number in the OSB neocortex may be associated with BPs spending a lesser p

224 white matter connectivity of the SC with the neocortex mirrored this pattern of asymmetries.

225 nt of structured network activity in a human neocortex model may follow stable genetic programming.

226 dle power increase in hippocampus (HIPP) and neocortex (NC) time-locked to individual hippocampal rip

227 e processing as a computational motif of the neocortex needs to be elaborated into theories of higher

228 In the developing mammalian neocortex, neural stem cells change competence over time

229 Here we show that in neocortex neuron-network coupling is neuronal cell-subty

230 representations of sensory perception in the neocortex of a Shank3B(-/-) mouse model of ASD.

231 expression studies show that changes in the neocortex of autism patients converge on common genes an

232 ay between CREB and neuronal activity in the neocortex of awake mice.

233 onal sources spread across the entire dorsal neocortex of awake, behaving mice during a three-option

234 aracteristics-has become abundant across the neocortex of humans, macaques and marmosets but not mice

235 t in rodents, they are present in the entire neocortex of many other species and their linear density

236 types produced by single progenitors in the neocortex of mice may result from stochastic rather than

237 from multiple neurons in the hippocampus and neocortex of rats with chronic temporal lobe epilepsy to

238 to EE, however, no changes were detected in neocortex or between Wt animals.

239 s is done through a graded coding, as in the neocortex, or a truly invariant code, in which the respo

240 set and the underlying cause of the atypical neocortex organization in OSB patients remain largely un

241 e studies have implicated Lewy bodies in the neocortex, others have pointed to alpha-synuclein pathol

242 malities, including the ipsilateral temporal neocortex (p = 0.006).

243 ABAergic interneurons in the hippocampus and neocortex, particularly fast-spiking parvalbumin-positiv

244 of graded responses and tuning curves in the neocortex, particularly in visual areas [1-15].

245 Layer 4 (L4) of mammalian neocortex plays a crucial role in cortical information p

246 For example, amyloid deposition in the neocortex precedes the spread of tau neurofibrillary tan

247 In motor neocortex, preparatory activity predictive of specific m

248 In the developing human neocortex, progenitor cells generate diverse cell types

249 ifically engage the hippocampus and temporal neocortex promoted increased interictal spiking within t

250 damental research into early circuits of the neocortex provides insight into the etiology of mental i

251 ation of structural hierarchies in the human neocortex, providing a model for adolescent development

252 de tracers.The major output cell type of the neocortex - pyramidal tract neurons (PTs) - send axonal

253 averaged beta power in primary somatosensory neocortex reflect a difference in the number of high-pow

254 Correct wiring in the neocortex requires that responses to an individual guida

255 Inhibition in neuronal networks of the neocortex serves a multitude of functions, such as balan

256 information, such as the hippocampus and the neocortex, share common cellular components and circuit

257 Subsequently, the size of ferret neocortex shot past that of the mouse.

258 rrections, indicate that the hippocampus and neocortex show a mixture of differences and similarities

259 ional IN variants in the hippocampus and the neocortex.SIGNIFICANCE STATEMENT Canonical interneuron (

260 hibitory circuit formation in the developing neocortex.SIGNIFICANCE STATEMENT Inhibitory interneurons

261 ve mechanism for hippocampal engagement with neocortex.SIGNIFICANCE STATEMENT Rodent hippocampal neur

262 we show that diet quality predicts relative neocortex size at least as well as, if not better than,

263 iring a volume of more than 1 mm(3) of mouse neocortex, spanning four different visual areas at synap

264 patially unstructured options depends on the neocortex, striatum, and amygdala.

265 d MDD, regional gray matter abnormalities in neocortex, thalamus, and striatum appear to be disorder-

266 In rats, MOR availabilities in the brain neocortex, thalamus, and striatum peaked at intermediate

267 a greater proportion of tau in the temporal neocortex than AD (t(41) = 2.0, p < 0.05), whereas AD ha

268 d a greater proportion of tau in the frontal neocortex than SYN + AD (t(41) = 3.3, p < 0.002).

269 resent a heterogenous group of cell types in neocortex that can be clustered based on developmental o

270 d later instructs another region, called the neocortex, that stores its content.

271 In the neocortex, the balance between activity and stability re

272 through its dense interconnections with the neocortex, the center of brain cognition.

273 transferring hippocampal information to the neocortex, the exact cortical destinations and the physi

274 Thus, in human and monkey neocortex, the LFP reflects primarily inhibitory neuron

275 The neocortex, the seat of higher cognitive functions, exhib

276 ensory neurons have been observed across the neocortex, this has led to some confusion about the feat

277 for regulating neural ensemble firing in the neocortex throughout development and adulthood.

278 ories of NRG3 isoforms (classes I-IV) in the neocortex throughout the human lifespan, examined whethe

279 s (SBs) in layer 4 (L4) of the temporal lobe neocortex (TLN) were quantitatively investigated.

280 ies reported the volume and thickness of the neocortex to be altered in children and adolescents diag

281 ropagate recent memory traces outward to the neocortex to facilitate memory consolidation there.

282 ivo two-photon calcium imaging in male mouse neocortex to reconstruct, with single-cell resolution, t

283 ng reflects the flow of information from the neocortex to the hippocampus during memory formation, an

284 The dramatic evolutionary expansion of the neocortex, together with a proliferation of specialized

285 Within the neocortex, two distinct subtypes of cortical areas can b

286 ual progenitor cells in the developing mouse neocortex using a combination of methods that together c

287 low physical contact, impact the developing neocortex via very early sensory experience as well as d

288 lyses revealed a single increase in relative neocortex volume at the origin of haplorrhines, and an i

289 Applying BRICseq to the mouse neocortex, we find that region-to-region connectivity pr

290 rat acute brain slices of the somatosensory neocortex, we found that theta burst neural activity pro

291 parahippocampal gyrus, and lateral temporal neocortex were at least twice as likely to be functional

292 affect neuronal development and function in neocortex, where Foxp2 is expressed.

293 o both excitatory and inhibitory synapses in neocortex, where it is organized into nanoscale puncta t

294 ence is mediated by both the hippocampus and neocortex, where the hippocampus separates overlapping b

295 both human and mouse pvBCs of supragranular neocortex, where they efficiently control discharge of t

296 reduction in the radial thickness of the OSB neocortex, which appears to be attributable a decrease i

297 reduction in the radial thickness of the OSB neocortex, which appears to be attributable to a massive

298 ta-amyloid (Abeta) facilitates its spread to neocortex, which may reflect the beginning of Alzheimer'

299 tion synthesized topological statistics from neocortex with a set of objective functions identifying

300 des support for an alternative view that the neocortex works with, but not follows, the hippocampus t