ライフサイエンスコーパス: neonatal mice

1 tokine interleukin-27 (IL-27) is elevated in neonatal mice.

2 into the subretinal space of LCA8-like model neonatal mice.

3 ivery to adult mice and systemic delivery to neonatal mice.

4 eminating systemically and causing sepsis in neonatal mice.

5 i-influenza virus response in both adult and neonatal mice.

6 d the frequency of iBALT to that observed in neonatal mice.

7 to induce TH1 responses after vaccination of neonatal mice.

8 secretion, and reduced diarrhea severity in neonatal mice.

9 in the injured hearts of both zebrafish and neonatal mice.

10 duct when microinjected into the kidneys of neonatal mice.

11 ant within a subunit tuberculosis vaccine in neonatal mice.

12 1-MMP expression pattern seen in rabbits and neonatal mice.

13 lungs, spleen, and lymph nodes of adult and neonatal mice.

14 ating LMC progenitor contribution to PLVs in neonatal mice.

15 fore or after RSV administration in adult or neonatal mice.

16 sive transfer of human anti-Dsg IgG4 mAbs to neonatal mice.

17 n by the protozoan Cryptosporidium parvum in neonatal mice.

18 rocedure to induce cardiac injury in 1-d-old neonatal mice.

19 ction, and improved survival above wild-type neonatal mice.

20 s, and no equivalent function was evident in neonatal mice.

21 ated gene) K(+) current in Purkinje cells of neonatal mice.

22 and prolongs the survival of RIPK1-deficient neonatal mice.

23 of caged glutamate in medullary slices from neonatal mice.

24 -4497 did not influence Inhba mRNA levels in neonatal mice.

25 e a mutation to explain the sld phenotype in neonatal mice.

26 roles for leptin receptor (LepRb) signals in neonatal mice.

27 re pathogenic in a passive transfer model in neonatal mice.

28 onocytes in adults, with similar findings in neonatal mice.

29 to the nucleus of alveolar macrophages from neonatal mice.

30 mu2 amino acid 208 modulates myocarditis in neonatal mice.

31 ansmit MCMV from latent mothers to breastfed neonatal mice.

32 e and children and causes biliary atresia in neonatal mice.

33 a are markedly more vulnerable to axotomy in neonatal mice.

34 tor neurons when injected intravenously into neonatal mice.

35 ed defective migration into the lungs of the neonatal mice.

36 y enhancing regulation of the UGT1A1 gene in neonatal mice.

37 ing rhythmically active in vitro slices from neonatal mice.

38 the cartilage of mineralizing vertebrae from neonatal mice.

39 lymphatic development in multiple organs of neonatal mice.

40 ion was tested with congenic C57BL/10 H-2(d) neonatal mice.

41 an in vitro medullary slice preparation from neonatal mice.

42 eloped that was successful in both adult and neonatal mice.

43 ha2 were attenuated in diarrhea induction in neonatal mice.

44 l enterotoxin capable of causing diarrhea in neonatal mice.

45 t spinal cords prepared from male and female neonatal mice.

46 ved indicators of myocardial regeneration in neonatal mice.

47 higher cDC2 density in the MZ, including in neonatal mice.

48 med the presence of proliferative BAs in the neonatal mice.

49 by a positive Nikolskiy sign in the skin of neonatal mice.

50 al resection-induced cardiac regeneration in neonatal mice.

51 al beta diversity but not alpha diversity in neonatal mice.

52 following C. parvum intestinal infection in neonatal mice.

53 pha, specifically in the collecting ducts of neonatal mice.

54 g strategy in cortical neurons and adult and neonatal mice.

55 immune responses can be avoided by treating neonatal mice.

56 as evaluated in vivo by using humanized TLR8 neonatal mice.

57 ate locomotor networks in the spinal cord of neonatal mice.

58 ulate locomotor output in the spinal cord of neonatal mice.

59 foundly mitigated induced NEC-like injury in neonatal mice.

60 fetus, as well as higher mortality rates in neonatal mice.

61 er than other B cell types and are sparse in neonatal mice.

62 a has been shown in experiments conducted in neonatal mice.

63 Transgenic (TG) and wild-type (WT) neonatal mice (10 mice per group) were exposed either to

64 thetic ligand for TLR-3, was administered to neonatal mice 14 h before cerebral HI.

65 In neonatal mice A alternata exposure induced higher serum

66 4Ralpha ASOs during primary RSV infection in neonatal mice abolished the pulmonary dysfunction normal

67 Fetal monocytes transferred to the lung of neonatal mice acquired an AMF phenotype via defined deve

68 CD4-deficient neonatal mice adoptively transferred with CD4(+) cells f

69 e, HVEM was sufficient to mediate disease in neonatal mice after direct intracranial inoculation, and

70 The NKT subset expanded in the lungs of neonatal mice after infection with influenza and also af

71 lar basis of the nearly complete recovery of neonatal mice after spinal cord injury, and suggest stra

72 h the recombinant HBc-E2 particles protected neonatal mice against lethal EV71 and CA16 infections.

73 Moreover, chronic ghrelin exposure in neonatal mice also attenuated leptin-induced STAT3 signa

74 Skin of neonatal mice and adult germ-free mice was seeded with l

75 t-natal life, we ablated Ihh in cartilage of neonatal mice and assessed the consequences on temporoma

76 In neonatal mice and cultured differentiating oligodendrocy

77 Blocking IL-13 after AAD was established in neonatal mice and did not reduce remodeling or IL-33 lev

78 nized by cell type, observed in RSV-infected neonatal mice and draw comparisons (when possible) to hu

79 ogically enriched CD71(+) erythroid cells in neonatal mice and human cord blood have distinctive immu

80 iation of cultured ENS progenitor cells from neonatal mice and humans.

81 nfluenza virus is qualitatively different in neonatal mice and may contribute to an increased morbidi

82 elivery across the central nervous system in neonatal mice and rats starting as early as P1 and persi

83 In cold thermosensors of neonatal mice and rats, ATP receptors were functionally

84 t5b-CA) allowed for Treg cell development in neonatal mice and restored Treg cell numbers in Cd28(-/-

85 u (PHF1) (a marker for neurodegeneration) in neonatal mice and reversed cAMP response element-binding

86 h a novel model of tendon regeneration using neonatal mice and show that neonates heal via formation

87 that developed during influenza infection in neonatal mice and that suppressed the subsequent develop

88 D4(+) T cells are required for protection of neonatal mice and that this protection may not require C

89 These populations began to expand in neonatal mice and, upon malignant transformation, result

90 cardiac tissues from C57BL/6 mouse embryos, neonatal mice, and adult mice was performed to evaluate

91 ased contractility during acute infection of neonatal mice, and persistent viral infection in the hea

92 The SSEA-1(+) PSCs were highly prevalent in neonatal mice, and they were rare in adult mice.

93 egeneration among model organisms, including neonatal mice, appear remarkably similar.

94 In conclusion, liver myeloid cells in neonatal mice are an important source of proinflammatory

95 Unlike adult mammals, zebrafish and neonatal mice are capable of heart regeneration followin

96 We find that IL-18-null neonatal mice are highly protected from polymicrobial se

97 However, we recently reported that neonatal mice are highly resistant to orogastric infecti

98 Neonatal mice are highly vulnerable to influenza and onl

99 Neonatal mice are lymphopenic within the first week of l

100 We report that neuromuscular junctions in neonatal mice are significantly more resistant to both h

101 Undernutrition in neonatal mice, as well as in weaned mice, intensified in

102 In neonatal mice, astrocytic PHD2 deficiency led to elevate

103 dritic cells (DCs) of wild-type and Batf3-/- neonatal mice at homoeostasis and investigated their rol

104 IL-4Ralpha were administered intranasally to neonatal mice at the time of primary infection.

105 levels were still reduced in hUGT1/Car(-/-) neonatal mice because of ROS induction of intestinal UGT

106 tetanus toxoid conjugate (dV-TT), and 98% of neonatal mice born to dams vaccinated with dV-TT survive

107 We found that allergen exposure in neonatal mice, but not in adult mice, elevated the level

108 with fibroblasts derived from embryonic and neonatal mice, but remained similar for fibroblasts from

109 in alveolar simplification mimicking BPD in neonatal mice, but the underlying mechanisms remain uncl

110 etinal neovascularization was established in neonatal mice by exposing them to 75% O(2) at postnatal

111 Oxygen-induced retinopathy was generated in neonatal mice by exposure to 75% oxygen from postnatal d

112 ypoxia-induced cardiopulmonary remodeling in neonatal mice, by decreasing progenitor cell recruitment

113 We found that the hearts of 1-day-old neonatal mice can regenerate after partial surgical rese

114 al development, and both adult zebrafish and neonatal mice can regenerate cardiac muscle after injury

115 these individuals induced skin blistering in neonatal mice caused by suprabasal acantholysis.

116 SPDEF or FOXA3 in airway epithelial cells in neonatal mice caused goblet cell differentiation, sponta

117 Sodium valproate (VPA) administered to neonatal mice causes cognitive and motor deficits simila

118 K1 grew rapidly in the peritoneal cavity of neonatal mice, causing fatal disease.

119 We show that neonatal mice challenged with arenavirus Tacaribe (TCRV)

120 virus that causes severe thymic necrosis in neonatal mice, characterized by a loss of CD4(+) T cells

121 ger in the IPL and 100% larger in the INL in neonatal mice compared with adults.

122 Interestingly, peritoneal fluid from neonatal mice contained significantly more total iron th

123 Surprisingly, neonatal mice (Day 14 and 21) were highly refractory to

124 Remarkably, neutrophil depletion in neonatal mice decreased the expression of the B cell act

125 numbers of facial motoneurons are doubled in neonatal mice deficient in either ZPK/DLK (zipper protei

126 infection was sufficient to transfer MCMV to neonatal mice, demonstrating that breast milk was a sour

127 ction of antagomirs specific to miR-26a into neonatal mice derepressed both Smad expression and activ

128 summary, the myocardial cryoinjury model in neonatal mice described here is a useful tool for cardia

129 Comparatively, neonatal mice did not develop overt skin inflammation, b

130 srupted, lipid absorption was perturbed, and neonatal mice died within days of birth.

131 Depletion of microglia in neonatal mice disrupts this healing process and stalls t

132 Subcutaneous injection of jacalin into neonatal mice drastically reduced PF IgG deposition at t

133 minergic control of spinal network output of neonatal mice during changes in spinal network excitabil

134 However, in neonatal mice EMG instrumentation could induce stress, a

135 homolog (PTEN) in the sensorimotor cortex of neonatal mice enables regeneration of corticospinal trac

136 luciferase/eGFP reporter (TFAR) cassettes to neonatal mice enabling longitudinal TFAR profiling by co

137 mmatory mediators, and oxidative stress when neonatal mice encounter severe hyperbilirubinemia.

138 ransient asymptomatic infection in adult and neonatal mice even at doses 100-fold higher than the LD5

139 Neonatal mice exhibit natural heart regeneration after m

140 However, both old and especially neonatal mice exhibited significant decreases in TCR div

141 cardiomyocyte ablation, we demonstrated that neonatal mice expand a population of embryonic-derived r

142 vels are significantly increased in lungs of neonatal mice exposed to hyperoxia.

143 sis and prevented alveolar simplification in neonatal mice exposed to hyperoxia.Conclusions: Cell the

144 Neonatal mice exposed to normoxia or hypoxia were random

145 ng during ongoing locomotor-like activity in neonatal mice expressing archaerhopsin-3 (Arch), halorho

146 Lastly, we show that neonatal mice expressing human FcRn are more susceptible

147 In neonatal mice expressing normal amounts of PHD2, exposur

148 stridiales, but not Bacteroidales, protected neonatal mice from pathogen infection and abrogated inte

149 and neonatal beta(7)(-/-) mice and adult and neonatal mice given blocking Abs to alpha(4)beta(7), MAd

150 IL-33 levels were quantified in neonatal mice given inhaled house dust mite (HDM), and t

151 Neonatal mice had high relative abundances of Streptococ

152 f postnatal window for heart regeneration in neonatal mice has led to the establishment of surgical m

153 Hyperoxia-exposed neonatal mice have increased caspase-1 activation, IL1be

154 logically identified skin sensory neurons in neonatal mice have shown that this region also receives

155 Neonatal mice have the capacity to regenerate their hear

156 We have studied the airway bioelectrics of neonatal mice homozygous for a null allele of Tmem16a (T

157 Our findings demonstrate in neonatal mice how gut flora synergizes with poly(I:C) to

158 Thus, in neonatal mice, IL-12, which accumulates in the environme

159 We found that neonatal mice immunized only once with the attenuated st

160 Inhibition of DDX3 activity or expression in neonatal mice impaired dendritic outgrowth and spine for

161 erve motor activity in medullary slices from neonatal mice in conditions where periods between succes

162 ex vivo somatosensory system preparations in neonatal mice in the hope that their small size might al

163 del for the study of cardiac regeneration in neonatal mice in which cryoinjury is used to induce hear

164 using isolated spinal cord preparations from neonatal mice in which locomotor-related output can be i

165 r constructs in transgenic mouse embryos and neonatal mice, in this report we define a minimal 1400 b

166 Surprisingly, in adult frogs and mice and in neonatal mice, in vivo and in vitro, the stereocilia wer

167 Mechanistically, this was explained in neonatal mice, in which long-chain, but not short-chain,

168 Neonatal mice incapable of classical or terminal complem

169 Leptin injection in neonatal mice increased bone morphogenic protein (BMP) s

170 ed with mature mice, rhinovirus infection in neonatal mice increased lung IL-13 and IL-25 production,

171 However, immunoproteasome deficiency in neonatal mice increased mortality and impaired IFN-gamma

172 Additionally, in wild-type neonatal mice inoculated intracranially, HSV antigen did

173 Inducible endothelial Mekk3 knockout in neonatal mice is lethal due to multiple intracranial hae

174 ility of neuromuscular junctions observed in neonatal mice is not determined by the maturity of the s

175 parvum, CCL20 production by the intestine of neonatal mice is reduced by a mechanism independent both

176 PLZF(+) innate lymphocytes in germ-free (GF) neonatal mice is restored by colonization with a human c

177 tory response to CO(2), we hypothesized that neonatal mice lacking 60-70% of their 5-HT neurones (Pet

178 In studies with neonatal mice lacking access to bacterial sphingolipids,

179 liferation was not significantly impaired in neonatal mice lacking AQP1, as quantified in flat-mounte

180 lacking CCM2 and in the lymphatic vessels of neonatal mice lacking HEG1 were associated with abnormal

181 However, motor neurons from neonatal mice lacking VIAAT in Renshaw cells received sp

182 on with respiratory syncytial virus (RSV) in neonatal mice leads to exacerbated disease if mice are r

183 ow that a crush injury to the spinal cord in neonatal mice leads to scar-free healing that permits th

184 inhibitory effect on angiogenesis process in neonatal mice lung following exposure to hyperoxia.

185 mpathetic axons derived from male and female neonatal mice maintain their structural integrity for ~1

186 In 1-wk-old neonatal mice, MF59 recruits and activates APCs, efficie

187 In neonatal mice motoneurons excite Renshaw cells by releas

188 Upon exposure to Ag on the day of birth, neonatal mice mount balanced primary Th1 and Th2 respons

189 Neonatal mice mounted a rapid and equivalent antimicrobi

190 Our study demonstrates that in neonatal mice NLF significantly limits mitochondrial cal

191 middle cerebral artery occlusion (tMCAO) in neonatal mice of both sexes in relation to blood-brain b

192 s in the nerves dissected from embryonic and neonatal mice of both sexes respond to the application o

193 Remarkably, neonatal mice of either the BALB/c or C57BL/6 mouse stra

194 tinal gene expression profiles in 17-day-old neonatal mice on a 2% LCPUFA feeding paradigm to identif

195 adult cells is diminished after transfer to neonatal mice or after co-culture with neonatal splenocy

196 n addition, the ablation of CD71(+) cells in neonatal mice, or the decline in number of these cells a

197 etinal vasculature, and imply that in normal neonatal mice, oxygen from the retinal circulation may p

198 In wild-type neonatal mice (postnatal day 0-1), we show that intraven

199 In neonatal mice, prior to P7, heart tissue can be regenera

200 Reovirus induces myocarditis in neonatal mice, providing a tractable model system for in

201 Neonatal mice raised on antibiotics or lacking the toll-

202 Intracerebroventricular ASO injection in neonatal mice recapitulates SMA-like progressive motor d

203 Neonatal mice receiving the adult CD8(+) T cells had sig

204 tion of adenovirus expressing mutant TLR4 to neonatal mice reduced the severity of NEC and increased

205 We conclude that, in neonatal mice, regenerated LV muscle has similar biomech

206 Reducing SMN in neonatal mice resulted in a classic SMA-like phenotype.

207 compounds (D152344, D153249 and D156844) to neonatal mice resulted in a dose-dependent increase in S

208 Ghrelin blockade in neonatal mice resulted in enhanced ARH neural projection

209 , intracranial infection of ZIKV in APP-null neonatal mice resulted in higher mortality and viral yie

210 ells into the external granule cell layer of neonatal mice resulted in the extension of parallel fibe

211 oduced fewer symptoms and lower mortality in neonatal mice, resulting in an attenuated form of biliar

212 In neonatal mice, rhesus rotavirus (RRV) can induce biliary

213 Olig1-null neonatal mice showed significant hypomyelination after m

214 oral administration of recombinant CCL20 to neonatal mice significantly reduced the parasite load by

215 In neonatal mice, Sox2-null inner pillar cells (IPCs, a sub

216 reating digit amputation wounds with BMP2 in neonatal mice stimulates endochondral ossification to re

217 fficient (Epas1+/-) and wild-type (Epas1+/+) neonatal mice subjected to an oxygen-induced retinopathy

218 Neonatal mice subjected to either increased or decreased

219 e (TG) emulsions provides neuroprotection in neonatal mice subjected to hypoxic-ischemic (H/I) brain

220 Neonatal mice suckled by OMV- or sham-immunized dams wer

221 Th2 cells were observed in IFN-alpha-treated neonatal mice, suggesting dual mechanisms of action.

222 pulmonary inflammation but not mortality in neonatal mice, suggesting that death in these mice was n

223 on of the left ventricular apex in 2-day-old neonatal mice, sympathetic nerve structures, which envel

224 of morphological changes occurred earlier in neonatal mice than in young adults.

225 n which human glial cells are engrafted into neonatal mice that are both immunodeficient and deficien

226 Neonatal mice that had in utero and early-life vitamin D

227 Here we show that neonatal mice that lack the capacity to produce IgG are

228 We have recently shown in neonatal mice that OXT receptors (OXTR) are present in s

229 Here we use optical methods to show in live neonatal mice that waves of spontaneous retinal activity

230 Here we show in neonatal mice, that neither reduction of sensory input t

231 e observed transmission of infection between neonatal mice, the first report of B. pertussis transmis

232 In neonatal mice, the heart can regenerate fully without sc

233 In neonatal mice, the microbiota induced TNF-alpha and IL-1

234 Indeed, in medullary slices from neonatal mice, the mu-opioid receptor (muOR) agonist DAM

235 On subcutaneous injection to neonatal mice, the TLR8 agonist-adjuvanted Ag85B peptide

236 Injection of AAV9-GFP into neonatal mice through the facial vein results in extensi

237 mpact on ciliogenesis in the hypothalamus of neonatal mice; through these effects they critically mod

238 the absence of systemic disease in wild-type neonatal mice, thus mirroring the key features of human

239 In utricles from neonatal mice, time-lapse recordings in the vicinity of

240 Retinopathy was induced by exposing neonatal mice to 75% oxygen from postnatal day (P) 7 to

241 urthermore, FcRn expression was required for neonatal mice to absorb TNP-specific IgE when fed as IgG

242 use white matter injury produced by exposing neonatal mice to chronic hypoxia-a paradigm that mimics

243 slices from wild-type (WT) and Lmx1b(f/f/p) neonatal mice to differentiate autoreceptor versus heter

244 ced propensity for weanling as compared with neonatal mice to form iBALT in response to acute LPS exp

245 Exposure of neonatal mice to hyperoxia enhanced sphingosine-1-phosph

246 ed that increased levels of IL-27 predispose neonatal mice to more severe infection during Gram-negat

247 Thus, exposure of neonatal mice to PC-bearing pneumococci significantly re

248 y through cranial windows in male and female neonatal mice to test the hypothesis that dynamics of de

249 Neonatal mice, unlike adults, lack factors required for

250 lerate FDC maturation and immune response in neonatal mice, using a pneumococcal polysaccharide of se

251 llowing intravenous injection into fetal and neonatal mice, using control uninjected age-matched mice

252 W:I-A(b)-specific naive T cells in different neonatal mice varied significantly in generation of Th1,

253 Brain remodeling after HI+/-MSC treatment in neonatal mice was analyzed using diffusion tensor magnet

254 ly returned to adult levels, TB clearance in neonatal mice was not associated with hepatic UGT1A1 exp

255 urprisingly, CD5 expression on B-1a cells of neonatal mice was only minimally compromised.

256 sequencing in naive CTL of differently aged neonatal mice was performed, which demonstrated differen

257 the neurogenic subventricular zone (SVZ) of neonatal mice, we deleted Tsc1 and generated olfactory l

258 role of PSCs in the bronchial epithelium of neonatal mice, we developed an enzyme-based digestion me

259 By using gene-deleted neonatal mice, we examined the contributions of the inna

260 immunological basis of these observations in neonatal mice, we found that antibody responses to infec

261 Using this endogenous regeneration model in neonatal mice, we have found that noggin treatment inhib

262 C57BL/6 adult and neonatal mice were challenged with C. rodentium, and a p

263 Neonatal mice were exposed to 95% oxygen for 4 days or r

264 separate experiments, FcRn(+/-) or FcRn(-/-) neonatal mice were gavage fed TNP-specific IgE as IgG(1)

265 Neonatal mice were injected intramuscularly with a human

266 Neonatal mice were inoculated with a recombinant CVB3 ex

267 Primary human AECs and neonatal mice were inoculated with RSV and murine Pneumo

268 Neonatal mice were maintained in a 75% oxygen atmosphere

269 Outbred CD1 neonatal mice were orally gavaged with one of two strain

270 Neonatal mice were primed with meningococcus serotype C

271 Immediately following birth, neonatal mice were prone to develop exaggerated airway e

272 After hyperoxia-treated neonatal mice were returned to ambient room air, retinal

273 Neonatal mice were subjected to a control diet (CTR) or

274 When neonatal mice were subjected to ischemia-induced retinop

275 Neonatal mice were transiently exposed to broad-spectrum

276 Pregnant C57BL/6 wild type dams and neonatal mice were treated with antibiotics before and/o

277 ection beyond the lungs was also detected in neonatal mice, which may contribute to the observed syst

278 -stimulated IGF-1 expression in the liver of neonatal mice, which plays a key role in the development

279 al denervation impairs heart regeneration in neonatal mice, which was rescued by the administration o

280 rmation of polyploid cardiomyocyte nuclei in neonatal mice, which, in turn, decreased myocardial rege

281 Administration of AAV9-GFP-AIP to neonatal mice with a known CPVT mutation (RYR2(R176Q/+))

282 zation, here we investigate vocalizations of neonatal mice with a reduction or absence of these compo

283 Treatment of neonatal mice with a single systemic dose of ASO partial

284 A single treatment of neonatal mice with an exon 5-targeted ASO-induced robust

285 how that B1 phenotype B cells are present in neonatal mice with B cell-specific KLF2 deficiency, sugg

286 Neonatal mice with deletion of PACAP in RTN neurons disp

287 Neonatal mice with disrupted LepRb-->ERK signaling displ

288 studies in livers from affected children and neonatal mice with experimental biliary atresia have sho

289 ective inhibition of hepatic GH signaling in neonatal mice with impaired expression of IGF-1 and IGFB

290 rated that knockdown of the miR-15 family in neonatal mice with locked nucleic acid-modified anti-miR

291 Here, we report that oral infection of neonatal mice with low doses of virulent Y. enterocoliti

292 n with influenza and also after treatment of neonatal mice with Nu-alpha-GalCer, which effectively in

293 ZDR/Wor rats, adult mice with I/R injury, or neonatal mice with OIR were injected within the vitreous

294 during sleep were clearly observed in these neonatal mice with or without EMG instrumentation.

295 c release in neurons following infection of neonatal mice with T3 reoviruses.

296 ced lung injury was significantly reduced in neonatal mice with targeted deletion of Chrm2, relative

297 IL-1beta production and skin inflammation in neonatal mice with the CAPS-associated Nlrp3 mutation.

298 Neonatal mice, with naturally expanded RORgammat+ gammad

299 were intravenously administered to fetal and neonatal mice, with noninjected age-matched mice used as

300 ed HSCs preferentially homed to the liver in neonatal mice yet showed balanced homing to the liver an