ライフサイエンスコーパス: neovascularization

1 ryonic development, organogenesis, and adult neovascularization.

2 neration followed by a postischemic aberrant neovascularization.

3 ntifying important factors in the process of neovascularization.

4 -like phenotype that impairs ischemic muscle neovascularization.

5 nal avascularization, followed by pathologic neovascularization.

6 reduced anterior chamber volume and corneal neovascularization.

7 al vessels at the site of baseline choroidal neovascularization.

8 to track the development of hypoxia-induced neovascularization.

9 d systemic inflammation and enhancing tissue neovascularization.

10 ng, circulating angiogenic cells, and tissue neovascularization.

11 s are due to exudative AMD, characterized by neovascularization.

12 in murine muscle tissue during postischemic neovascularization.

13 only misdiagnosed as disc edema or choroidal neovascularization.

14 nduced retinopathy and laser-induced choroid neovascularization.

15 P), respectively, further confirmed improved neovascularization.

16 growth through decreasing proliferation, and neovascularization.

17 pixels of FS were preceded by components of neovascularization.

18 e no reports of neovascular glaucoma or iris neovascularization.

19 ting plays an intricate role in postischemic neovascularization.

20 implicated in the pathogenesis of choroidal neovascularization.

21 ited the capacity for cell proliferation and neovascularization.

22 nduced retinopathy and laser-induced choroid neovascularization.

23 rmal and with macular degeneration/choroidal neovascularization.

24 absence, and high-grade CE, the presence of neovascularization.

25 ticle deposition occurred in areas of plaque neovascularization.

26 ntraocular injection of ManN induces retinal neovascularization.

27 en-induced uveitis and laser-induced retinal neovascularization.

28 ne editing or 2'-O-ribose-methylation during neovascularization.

29 ive strategy for treating pathologic retinal neovascularization.

30 showed large intrahepatic tumors with active neovascularization.

31 as vascular malformations, nonperfusion, and neovascularization.

32 wth factor (VEGF) is a powerful regulator of neovascularization.

33 mbination with exogenous Ang1, for effective neovascularization.

34 The underlying mechanism may be involved in neovascularization.

35 The corneas healed with scar formation and neovascularization.

36 F therapy, and may be associated with type 3 neovascularization.

37 ral cornea, accompanied by corneal edema and neovascularization.

38 pathogenic role in retinal inflammation and neovascularization.

39 l development and the pathobiology of ocular neovascularization.

40 a unique risk for the development of GA and neovascularization.

41 ry cell infiltration, tissue destruction and neovascularization.

42 sit, visual acuity was 20/20 with no sign of neovascularization.

43 tric oxide (NO) in macrophages and choroidal neovascularization.

44 el therapeutic target for reducing choroidal neovascularization.

45 rgeting the tumor endothelium to block tumor neovascularization.

46 telliform dystrophy and unilateral choroidal neovascularization.

47 lyzed for macular fluid secondary to macular neovascularization.

48 nt and recruited endothelial progenitors for neovascularization.

49 %) showed leakage and 16 eyes (14.2%) showed neovascularization.

50 rative diabetic retinopathy (PDR) is retinal neovascularization.

51 enesis, given the established role of NIK in neovascularization.

52 real anti-VEGF injections for recurrent iris neovascularization.

53 regression and retinal ischemia followed by neovascularization.

54 al hypoxia, preventing subsequent pathogenic neovascularization.

55 sufficient to achieve regression of retinal neovascularization.

56 eyes received intravitreous bevacizumab for neovascularization.

57 ibitors could be repurposed to treat retinal neovascularization.

58 egeneration with frank atrophy of the RPE or neovascularization.

59 l mediator of diabetes-related impairment in neovascularization.

60 tervals and informed of the greater risk for neovascularization.

61 ruption (77% vs 3%, P < .001), and choroidal neovascularization (16% vs 0%, P = .028).

62 Group 1 developed more central corneal neovascularization (22 eyes; 73.3%) compared to Group 2

63 that was associated with increased choroidal neovascularization, a hallmark of advanced exudative AMD

64 Current treatments for choroidal neovascularization, a major cause of blindness for patie

65 nt epithelium (RPE) abnormalities, choroidal neovascularization, acquired vitelliform lesions (AVLs),

66 Biomarker maps of neovascularization activity (microvessel radius, microve

67 onance (MR) imaging of oxygen metabolism and neovascularization activity for grading and characteriza

68 atory infiltrate, fibrotic degeneration, and neovascularization after 6 hours and 10 hours of CI.

69 teries during development and during cardiac neovascularization after injury are poorly understood.

70 that MMP12 inhibits corneal inflammation and neovascularization after injury through its regulation o

71 rowth in the neonate, none are active during neovascularization after MI in adult hearts.

72 about the role of MDSC in the regulation of neovascularization after transplantation.

73 Eyes with initial retinal neovascularization all responded to the adjuvant treatme

74 s in the pupillary area associated with iris neovascularization and a subluxated and notched lens.

75 ed to treat cardiac hypertrophy by improving neovascularization and altering the paracrine effect of

76 e effects translated to a reduction in tumor neovascularization and an induction of tumor cell death

77 elease high amounts of VEGF-A, thus inducing neovascularization and cardiac repair.

78 activating a fetal gene programme to promote neovascularization and cardiomyogenesis.

79 immunohistochemistry revealed abundant lung neovascularization and cellular proliferation in PE that

80 nal lesions can be associated with choroidal neovascularization and central serous chorioretinopathy

81 ch(m1Pas) mutant mice showed reduced retinal neovascularization and endothelial cell proliferation in

82 a (HIF-1alpha) activation, thereby promoting neovascularization and enhancing regeneration in chronic

83 In zones 2 and 3, neovascularization and geographic atrophy (GA) were pres

84 ls in gliomas as a pivotal modifier of tumor neovascularization and immunosuppression, strengthening

85 henotype and their pathogenic roles in tumor neovascularization and immunosuppression.Significance: T

86 ts reduces cardiomyocyte apoptosis, enhances neovascularization and improves left ventricular functio

87 as a key player in the development of ocular neovascularization and indicate a fundamental role of TG

88 l prolonged graft survival by downregulating neovascularization and inflammation factors, while promo

89 ptor played a permissive role in suppressing neovascularization and inflammation in vivo Comparing AG

90 RD, whereas the other child showed extensive neovascularization and later progressed to combined trac

91 Ultrasonography showed decreased neovascularization and lesion skin depth in the MABp1 gr

92 Inhibition of neovascularization and modulation of the production of I

93 ing Sema3e promoted disoriented pathological neovascularization and partially abolished the inhibitor

94 reated bone marrow cells (evMDSC) suppressed neovascularization and prolonged corneal allograft survi

95 chemical inhibition of Fech reduces retinal neovascularization and promotes physiological angiogenes

96 ion of expression of alpha SMA and TGF beta, neovascularization and re-epithelialization.

97 molecular targets to therapeutically promote neovascularization and regeneration of the infarcted hea

98 bitor substantially reduced the pathological neovascularization and rescued visual function in Vldlr(

99 esses to help clear tumors by blunting tumor neovascularization and restoring immunosurveillance.

100 inst ocular HSV-1 challenge, reducing ocular neovascularization and suppressing peripheral nerve viru

101 Peritoneal pouch islet grafts showed high neovascularization and sustained insulin and glucagon ex

102 -mediated leukostasis, retinal ischemia, and neovascularization and their contribution to pathologica

103 had angioid streaks complicated by choroidal neovascularization and underwent prior thermal laser pho

104 ere complemented by in vivo investigation of neovascularization and vascular remodeling after ischemi

105 on stump healing, perfusion, adductor muscle neovascularization, and decreased muscle fiber damage.

106 including corneal opacification, ulceration, neovascularization, and ectasia.

107 evelopment of chronic inflammation, abnormal neovascularization, and fibrosis.

108 inal pigment epithelium abnormalities, AVLs, neovascularization, and GA occurred at a frequency of 47

109 on VA, OCT changes, development of choroidal neovascularization, and length of follow-up.

110 in recovering cardiac function, stimulating neovascularization, and promoting myocardial remodeling.

111 may be involved in corneal wound healing and neovascularization, and thus, may serve as targets for p

112 induced retinopathy, laser-induced choroidal neovascularization, and transgenic mouse models with def

113 entation, and vascularity; incidence of iris neovascularization; and radiation-related complications.

114 improved re-epithelialization and increased neovascularization; and with decreased sustained pro-inf

115 ug assay, which mimics ischemic/inflammatory neovascularization, angiogenesis was dramatically upregu

116 nal microvascular abnormalities (IRMAs), and neovascularization appeared to originate from areas of r

117 Inflammation and intraplaque neovascularization are acknowledged to be 2 features of

118 Inflammation and intraplaque neovascularization are not systematically associated in

119 rs with the presence of subretinal/choroidal neovascularization as indicated by International Classif

120 wn to promote cell proliferation, leading to neovascularization as well as neuroprotection in mammals

121 h deficient or spontaneous retinal/choroidal neovascularization, as well as models with induced corne

122 on, vascular leakage, neurodegeneration, and neovascularization associated with retinal diseases in a

123 Among eyes with versus without resolved neovascularization at 6 months, the median (interquartil

124 patients also showed no detectable choroidal neovascularization at week 12 on fluorescein angiography

125 This may be related to decreased neovascularization, because decreased CD31 staining, ind

126 nimals based on survival and reduced corneal neovascularization but displayed similar levels of corne

127 during the clinical disease period decreased neovascularization but increased the opacity in HSV-1-in

128 rnea pathology was mixed with a reduction in neovascularization but no change in opacity.

129 In this study, we imaged neovascularization by label-free dark-field microscopy o

130 antiangiogenic factors leads to the loss of neovascularization capacity in pathologic conditions.

131 almia, retinal dysplasia, keratitis, corneal neovascularization, cataracts, and calcification.

132 ion MR imaging-derived oxygen metabolism and neovascularization characterization may be useful for gr

133 between all rare pLoF variants and choroidal neovascularization (CNV) (OR, 1.34; 95% CI, 1.04-1.73; P

134 Baseline occult-type choroidal neovascularization (CNV) (P = .0156) and retinal fluid (

135 ng for early detection of incident choroidal neovascularization (CNV) among patients with age-related

136 Choroidal neovascularization (CNV) and capillary dilations were qu

137 acrophages play a critical role in choroidal neovascularization (CNV) and may, therefore, be potentia

138 ed macular degeneration-associated choroidal neovascularization (CNV) and VA between 20/25 and 20/320

139 lemia, worse visual acuity, larger choroidal neovascularization (CNV) area, retinal angiomatous proli

140 The mean VA and the type of the choroidal neovascularization (CNV) at the start of treatment were

141 Choroidal neovascularization (CNV) can complicate AMD and lead to

142 se mice develop significantly less choroidal neovascularization (CNV) compared to wild-type controls

143 s over time and their influence on choroidal neovascularization (CNV) development.

144 ography (OCTA) in the detection of choroidal neovascularization (CNV) in age-related macular degenera

145 have been implicated in promoting choroidal neovascularization (CNV) in age-related macular degenera

146 ing the transcriptional profile of choroidal neovascularization (CNV) in body donor eyes with neovasc

147 Proxima A had bilateral GA without choroidal neovascularization (CNV) in either eye (N = 295).

148 s and natural history of quiescent choroidal neovascularization (CNV) in geographic atrophy (GA) seco

149 Choroidal neovascularization (CNV) in pregnancy has rarely been de

150 in both eyes (GA:GA); GA in 1 eye, choroidal neovascularization (CNV) in the fellow eye (GA:CNV); GA

151 atuses were analyzed: (1) no GA or choroidal neovascularization (CNV) in the fellow eye, (2) GA in th

152 Rap1a expression and inhibition of choroidal neovascularization (CNV) induced by laser injury.

153 Choroidal neovascularization (CNV) is a major cause of visual impa

154 Choroidal neovascularization (CNV) is a prevalent cause of vision

155 Choroidal neovascularization (CNV) is the major cause of vision lo

156 Myopic choroidal neovascularization (CNV) is the most common sight-threat

157 Choroidal neovascularization (CNV) leads to loss of vision in pati

158 prominent in patients with classic choroidal neovascularization (CNV) than those with occult CNV (P <

159 Choroidal neovascularization (CNV) was manually segmented on OCTA

160 cytes or astrocytes, laser-induced choroidal neovascularization (CNV) was significantly reduced in Bc

161 main infiltrating immune cells in choroidal neovascularization (CNV), a hallmark of the human wet, o

162 The molecular pathogenesis of choroidal neovascularization (CNV), an angiogenic process that cri

163 retinas treated with laser-induced choroidal neovascularization (CNV), bright white-light exposure, a

164 wth of choroidal blood vessels, or choroidal neovascularization (CNV), is a hallmark of the neovascul

165 types; geographic atrophy (GA) and choroidal neovascularization (CNV).

166 so lose vision as a consequence of choroidal neovascularization (CNV).

167 travitreal anti-VEGF for traumatic choroidal neovascularizations (CNV).

168 rom pathologic RPE detachments and choroidal neovascularizations (CNVs).

169 n angiography due to suspected peripapillary neovascularizations collapsed after the injection of flu

170 expressing HLEKs elicited a lesser degree of neovascularization compared with controls.

171 , SLN expression, mitochondrial content, and neovascularization, compared with WT mice.

172 Our findings support that neovascularization contributes to behavioral recovery af

173 y (AS-OCTA) to determine severity of corneal neovascularization (CoNV).

174 Choroidal neovascularization developed in 1 eye in the PPV group a

175 Hyperreflectivity and neovascularization developed within an EZ loss area or a

176 (N = 1817) with untreated, active choroidal neovascularization due to age-related macular degenerati

177 y to prevent further vision loss and retinal neovascularization due to extensive retinal ischemia.

178 The presence of intraplaque neovascularization during contrast-enhanced ultrasound w

179 Two eyes were associated with a type 3 neovascularization eccentric to PEVAC.

180 presence of neovascularization of the disc, neovascularization elsewhere, or intraretinal microvascu

181 of the optic disc (NVDs) and one patient had neovascularizations elsewhere (NVEs) and preretinal hemo

182 We found that macrophage infiltration and neovascularization following CCL2 blockade was significa

183 significantly decreases pathological retinal neovascularization following OIR.

184 of the fellow eyes with RAP did not develop neovascularization for 3.5 years.

185 of the fellow eyes with CNV did not develop neovascularization for 5.3 years, whereas the 50% of the

186 butions to AMD-related neurodegeneration and neovascularization, highlighting TGFbeta signaling as a

187 Only patients with naive unilateral forms of neovascularization in 1 eye were included in this study.

188 ularization in 3 eyes and inactive choroidal neovascularization in 1 eye.

189 low signal corresponding to active choroidal neovascularization in 3 eyes and inactive choroidal neov

190 itiation and growth of spontaneous choroidal neovascularization in a mouse model, and the combination

191 angiogenic factor promoting the pathological neovascularization in age-related macular degeneration (

192 more, this scaffold laden with EPCs promoted neovascularization in an animal model of hind limb ische

193 -dimensional (3D) analysis strategy to study neovascularization in biomaterials relevant for bone reg

194 oducts of cytochrome P450 oxidase 2C promote neovascularization in both the retina and choroid, which

195 ation affects organ function and therapeutic neovascularization in diabetes mellitus.

196 dence of or previous treatment for choroidal neovascularization in either eye and best-corrected visu

197 , reduced MI scar size, and enhanced post-MI neovascularization in MI mouse model.

198 microparticles potently suppresses choroidal neovascularization in mice for six months and in another

199 Although pathologic neovascularization in oxygen-induced ischemic retinopath

200 multimodal imaging, helps diagnose choroidal neovascularization in patients with Malattia Leventinese

201 Neovascularization in PDR can be identified at baseline

202 edly attenuates healing after MI by reducing neovascularization in peri-infarct zones.

203 ne disruption, RPE disruption, and choroidal neovascularization in peripapillary combined hamartoma.

204 ermal blood vessels and improve the impaired neovascularization in skin-embedded Matrigel plug.

205 e assessment of inflammation and intraplaque neovascularization in the carotid plaque of symptomatic

206 were best-corrected visual acuity (BCVA) and neovascularization in the central 5 mm of the cornea.

207 airment of the cerebral vessel perfusion and neovascularization in the cortex neighboring the stroke-

208 teractions that are essential for pathologic neovascularization in the eye.

209 The time of absence of neovascularization in the fellow eye was calculated.

210 glycolytic enzymes and reduces pathological neovascularization in the OIR mice.

211 ed severely disorganized collagen fibers and neovascularization in the tendon midsubstance.

212 This study showed that the incidence of neovascularization in the unaffected fellow eye increase

213 lary network formation in Matrigel plugs and neovascularization in vivo.

214 dothelial cell growth in vitro and choroidal neovascularization in vivo.

215 tion significantly impaired tumor growth and neovascularization in vivo.

216 Neurokinin-1, significantly reduced corneal neovascularization in vivo.

217 and podocyte-derived VEGF is associated with neovascularization in wet age-related macular degenerati

218 Corneal neovascularization increases the risk of T cell-mediated

219 oietin-1 (Ang1) contribute differentially to neovascularization induced by nitric oxide (NO)-mediated

220 Epiretinal neovascularization is a novel finding in MacTel type 2.

221 n treating uveitis and ocular diseases where neovascularization is a significant part of the patholog

222 However, aberrant neovascularization is an essential pathogenic mechanism

223 However, endogenous neovascularization is inefficient and the regulatory pat

224 g involved in miR93-mediated ischemic muscle neovascularization is not clear.

225 Ocular neovascularization is strongly associated with inflammat

226 ers of cell proliferation (Ki-67), decreased neovascularization (laminin and alphaSMA), in addition t

227 Pigmented mice with laser-induced choroidal neovascularization lesions (n = 7 eyes) were also imaged

228 oth area and number of spontaneous choroidal neovascularization lesions.

229 le for TLR2 in the pathogenesis of choroidal neovascularization, likely by promoting inflammation of

230 o studies were used to assess the myocardial neovascularization, macrophage content, and activity in

231 hypoxic response initiates and drives type 3 neovascularization, mainly in the outer retina.

232 ogenous VEGF expression as a therapeutic for neovascularization may not be successful.

233 n eyes with treatment-naive myopic choroidal neovascularization (mCNV) in the United States.

234 cious cell transplantation therapy to induce neovascularization-mediated diabetic wound tissue regene

235 r degeneration (AMD) that had type 1 macular neovascularization (MNV) (91.1%).

236 Type 2 macular neovascularization (MNV) is supposed to be a rare condit

237 ntify the size and vessel density of macular neovascularization (MNV) using optical coherence tomogra

238 d by thick drusen, 54% by subretinal macular neovascularization (MNV), and 22.5% by no detectable OCT

239 ble-layer sign predicted subclinical macular neovascularization (MNV).

240 l growth factor (VEGF) treatment for macular neovascularization (MNV).

241 aluable information regarding type 3 macular neovascularization (MNV).

242 angiogenic functions of ECs and impair brain neovascularization, neuronal survival and cognitive reco

243 a enhanced immune cell dynamics and promoted neovascularization, neutrophil clearance, cardiomyocyte

244 itment in zebrafish and observed compromised neovascularization, neutrophil clearance, cardiomyocyte

245 l Modification diagnosis of "362.16: Retinal Neovascularization NOS." Type of initial treatment for m

246 reviewed the angiograms in the 2 groups for neovascularization (NV) and other abnormal vascular patt

247 fluorescein angiography (FA) for evaluating neovascularization (NV) before and after panretinal phot

248 lyze the long-term growth patterns of type 1 neovascularization (NV) in eyes with age-related macular

249 Fzd7 or CRD significantly attenuated retinal neovascularization (NV) in mice with OIR.

250 the ability of ophthalmologists to identify neovascularization (NV) in patients with proliferative d

251 Areas of neovascularization (NV) in proliferative diabetic retino

252 bus in corneal avascularity and pathological neovascularization (NV) is not well understood.

253 bination group had a significant decrease of neovascularization (NV) leakage area than the PRP group

254 Corneal neovascularization (NV) predisposes patients to compromi

255 e detection of regression or reactivation of neovascularization (NV), B-scan OCTA had the highest det

256 malities (IRMAs) are a known risk factor for neovascularization (NV), but whether IRMA represents a b

257 without evident signs of active or regressed neovascularization [NV] at baseline), CFP may be suffici

258 ation and an inability to undergo pathologic neovascularization observed in mice globally lacking Bcl

259 a promising effective method in reduction of neovascularization of a ROP rat model.

260 yestradiol (2-ME) nanoemulsion in regressing neovascularization of a ROP rat model.

261 To facilitate recovery, the brain stimulates neovascularization of damaged tissue via sprouting angio

262 Emerging role of dopamine in neovascularization of pheochromocytoma and paraganglioma

263 The presence of neovascularization of the disc, neovascularization elsew

264 ere was a significantly greater incidence of neovascularization of the iris in the IVI arm compared w

265 Both patients had neovascularization of the optic disc (NVDs) and one pati

266 Neovascularization of venous origin demonstrated slower

267 on <90 days; (2) absence of anterior segment neovascularization on presentation; (3) no intravitreal

268 If a neovascularization or macular hole were present, bilater

269 The latter were compatible with type 3 neovascularization or retinal angiomatous proliferation

270 rrhage, retinal detachment, anterior segment neovascularization, or neovascular glaucoma.

271 d natural history of macular retinochoroidal neovascularization (RCN) in enhanced S-cone syndrome (ES

272 Corneal graft survival, opacity, neovascularization, re-epithelization, immune cell infil

273 eyes with retinal vasculitis and the rate of neovascularization relapse in ischemic vasculitis.

274 r, and no recurrence of type 1 ROP or severe neovascularization requiring additional treatment within

275 of ranibizumab-assigned eyes showed complete neovascularization resolution and an additional 60% (113

276 At 6 months, 52% (80 of 153) showed neovascularization resolution, 3% (4) were improved, 37%

277 At 2 years, 43% (66 of 154) showed neovascularization resolution, 5% (7) showed improvement

278 pathway in the adult retina led to long-term neovascularization, retinal hemorrhages and compromised

279 ency for visualizing newly developed retinal neovascularization (RNV) and to monitor the dynamic chan

280 antly prolonged with lower graft opacity and neovascularization scores in 0.4% and 2.0% ripasudil-tre

281 nts, aged >/=50 years, with active choroidal neovascularization secondary to AMD.

282 (32%) had neovascular AMD and 1 eye (3%) had neovascularization secondary to pseudoxanthoma elasticum

283 ative intraretinal cystic changes, choroidal neovascularization, serous retinal elevations mimicking

284 Peripheral neovascularization, stromal scarring, and features of li

285 Despite robust neovascularization, the microcirculation formed by regen

286 ams and OCT images were graded for choroidal neovascularization type.

287 VEGF is a critical driver of ocular neovascularization under disease conditions.

288 eart, affecting the amplitude of therapeutic neovascularization via rAAV.Tbeta4 in a translational la

289 005), and more visits at which the choroidal neovascularization was graded as active (OR, 1.97 for ey

290 Retinal neovascularization was present bilaterally in 2 patients

291 asp-8 in ECs was beneficial, as pathological neovascularization was reduced in Casp-8ECKO pups.

292 er 6 months, injections could be deferred if neovascularization was stable over 3 consecutive visits

293 Occurrence of GA and neovascularization were important determinants of final

294 No signs of choroidal neovascularization were observed.

295 1+/-57; P = 0.0020) and regression of fundus neovascularization when present.

296 , reduced MI scar size, and promoted post-MI neovascularization, whereas IL-10 knockout EPC-derived e

297 doT-derived cells are substantial sources of neovascularization, which can be manipulated to attenuat

298 But FECH has not been explored in retinal neovascularization, which underlies diseases like prolif

299 OCTA is useful to detect neovascularization without injecting a contrast product,

300 If neovascularization worsened, monthly treatment resumed.