ライフサイエンスコーパス: nerve regeneration

1 resting therapeutic target for human sensory nerve regeneration.

2 proline/glutamine rich) that attenuate optic nerve regeneration.

3 europoietic cytokine receptors in peripheral nerve regeneration.

4 to these disorders, since they could promote nerve regeneration.

5 d at maximum speeds comparable to peripheral nerve regeneration.

6 homophilic adhesion molecule and involved in nerve regeneration.

7 tion on injuries, aiming to allow peripheral nerve regeneration.

8 ndent contribution of SCs and fibroblasts to nerve regeneration.

9 navigation during embryonic development and nerve regeneration.

10 biological processes such as myelination and nerve regeneration.

11 pobec2b were found to be essential for optic nerve regeneration.

12 o a progenitor-like state, in which they aid nerve regeneration.

13 antibody exhibited >80% reduction in corneal nerve regeneration.

14 continuing and essential role in successful nerve regeneration.

15 eutrophils, platelets, and VEGF-A in corneal nerve regeneration.

16 iation states required to support peripheral nerve regeneration.

17 transcriptional program and is critical for nerve regeneration.

18 platelet infiltration and >50% reduction in nerve regeneration.

19 nal alterations observed in CH neurons after nerve regeneration.

20 use cutaneous CH neurons following saphenous nerve regeneration.

21 e fiber regeneration may account for altered nerve regeneration.

22 s as a key negative regulator of adult optic nerve regeneration.

23 transporting protein, facilitates olfactory nerve regeneration.

24 al factors seem to play a role in successful nerve regeneration.

25 mice, suggesting apoE facilitates olfactory nerve regeneration.

26 ggested, so we tested its role in peripheral nerve regeneration.

27 th factor alternative to enhance the rate of nerve regeneration.

28 role of RAGE in these distinct cell types on nerve regeneration.

29 omponent of the myelin-derived inhibition of nerve regeneration.

30 ing chemorepellant growth cone responses and nerve regeneration.

31 ferent indicators of corneal innervation and nerve regeneration.

32 binds to the nerve cell surface and inhibits nerve regeneration.

33 a potential therapeutic target for promoting nerve regeneration.

34 hose genes induced during successful sciatic nerve regeneration.

35 yelination is a critical step for functional nerve regeneration.

36 s for cancer, pathological angiogenesis, and nerve regeneration.

37 y be a significant contributor to successful nerve regeneration.

38 nerve compared with sham counterparts during nerve regeneration.

39 chwann cells, whose presence is critical for nerve regeneration.

40 formation of neuromuscular junctions during nerve regeneration.

41 ests that galanin plays a role in peripheral nerve regeneration.

42 expression appears independent of peripheral nerve regeneration.

43 -estradiol confirmed its function in corneal nerve regeneration.

44 d, replicating previous studies of olfactory nerve regeneration.

45 lly using such polymers to stimulate in vivo nerve regeneration.

46 licated for the first time in the process of nerve regeneration.

47 ately induced with gRICH68 mRNA during optic nerve regeneration.

48 ult during tumorigenesis, wound healing, and nerve regeneration.

49 induced in the goldfish retina during optic nerve regeneration.

50 s surgically repaired to facilitate accurate nerve regeneration.

51 ting cell survival, synaptic remodeling, and nerve regeneration.

52 uncharacterized role for glial ADAM17 during nerve regeneration.

53 s and nodes of Ranvier, and impaired sciatic nerve regeneration.

54 sexual divergence in corneal innervation and nerve regeneration.

55 luding many genes associated with peripheral nerve regeneration.

56 migration, which is required for peripheral nerve regeneration.

57 chromatin architecture and severely impaired nerve regeneration.

58 is and regulating immune microenvironment of nerve regeneration.

59 rcuitry, neither of which reverse even after nerve regeneration.

60 circuits, degrading motor performance after nerve regeneration.

61 d DMAPT was similarly effective in promoting nerve regeneration.

62 on factors have become an emerging option in nerve regeneration.

63 tion is similarly critical during peripheral nerve regeneration.

64 re potent, increasing cornea sensitivity and nerve regeneration.

65 on and domesticating astrocyte behaviors for nerve regeneration.

66 a major constraint on the rate of peripheral nerve regeneration.

67 used in studies of corneal wound healing and nerve regeneration.

68 rylation of CRMP2 in RGCs and improved optic nerve regeneration.

69 ightly, but significantly, compromised optic nerve regeneration.

70 valent requirement of active CRMP2 for optic nerve regeneration.

71 nt of mRNAs related to protein synthesis and nerve regeneration.

72 at two differentiation stages on peripheral nerve regeneration.

73 anoreceptor and sensory fiber function after nerve regeneration.

74 eprogram Schwann cells to promote peripheral nerve regeneration.

75 bution of MAP7 to neurological disorders and nerve regeneration.

76 ed peripheral nerve repair profoundly limits nerve regeneration.

77 duit with designer structures for peripheral nerve regeneration.

78 physiological pain, neuronal cell death, and nerve regeneration.

79 naptic communication, synaptic strength, and nerve regeneration.

80 3 activity show markedly accelerated sciatic nerve regeneration.

81 factor required for Schwann cells to support nerve regeneration.

82 well as JUN, all of which are essential for nerve regeneration.

83 ed proteins have been shown to contribute to nerve regeneration.

84 d cells for beta(1, 3)-glucan-elicited optic nerve regeneration.

85 ore potential targets for promoting auditory nerve regeneration.

86 in the successful regeneration of peripheral nerves regeneration.

87 protocols designed to facilitate or restrict nerve regeneration: 1) ligation, in which transected axo

88 For successful nerve regeneration, a coordinated shift in gene expressi

89 To investigate the effects of CES on nerve regeneration, a series of kinetic, kinematic, skil

90 gnificantly improved the distance of sensory nerve regeneration achieved after nerve crush injury com

91 ncoding galanin exhibit decreased peripheral nerve regeneration after a lesion.

92 n of IGF-1 in skeletal muscle enhances motor nerve regeneration after a nerve crush injury.

93 eceptor with Herceptin unexpectedly enhances nerve regeneration after acute and delayed nerve repair.

94 nvestigated the process of axon regrowth and nerve regeneration after complete transection of the Oct

95 Peripheral nerve regeneration after injury is dependent upon implem

96 Nerve regeneration after injury must occur in a timely f

97 Quantification of peripheral nerve regeneration after injury relies upon subjective o

98 factors (FGFs) are key players in peripheral nerve regeneration after injury.

99 al stimulation may be effective in promoting nerve regeneration after injury.

100 ated the ability of diffusion MRI to monitor nerve regeneration after injury/repair.

101 ma7a in naive corneas and corneas undergoing nerve regeneration after lamellar corneal surgery in thy

102 significantly improve the pace and degree of nerve regeneration after nerve injury and hindlimb trans

103 could be an important step towards promoting nerve regeneration after stroke or spinal cord injury.

104 a implanted pellets showed increased corneal nerve regeneration after superficial injury compared wit

105 outgrowth during development and peripheral nerve regeneration after trauma, and hence to the develo

106 data suggest a new mechanism for peripheral nerve regeneration along a tubulated gap.

107 nophilins can regulate neuronal survival and nerve regeneration although the molecular mechanisms are

108 Ts) have the potential to promote peripheral nerve regeneration, although with limited capacity and f

109 there was significant stimulation of corneal nerve regeneration and a reduction in nerve edema after

110 in developmental myelination and functional nerve regeneration and as a novel transcription factor r

111 They play a crucial role in nerve regeneration and can be used clinically in the rep

112 ly important in regulating cell migration in nerve regeneration and cortical development.

113 play a role in dedifferentiation as well as nerve regeneration and degeneration.

114 , the neurite outgrowth factor that inhibits nerve regeneration and destabilizes neuromuscular juncti

115 eneration studies may propel improvements in nerve regeneration and draw critical parallels to mechan

116 and blocking of NKG2D also inhibited corneal nerve regeneration and epithelial healing (P < 0.01).

117 600 mM M6P to the nerve repair site enhances nerve regeneration and functional recovery in the early

118 LY117018 may markedly accelerate peripheral nerve regeneration and functional recovery through activ

119 veloping therapeutic strategies that improve nerve regeneration and functional recovery.

120 ction in retinal ganglion cells during optic nerve regeneration and in a subset of Muller glia that p

121 esults suggest that ninjurin plays a role in nerve regeneration and in the formation and function of

122 effect of Sema7a supplementation on corneal nerve regeneration and inflammation.

123 ively in the cornea, and potently stimulates nerve regeneration and inflammatory cell influx.

124 Therefore, this immune semaphorin links nerve regeneration and inflammatory processes in the cor

125 this signaling mechanism upregulates corneal nerve regeneration and may be targeted in neurotrophic k

126 ie the functional alterations observed after nerve regeneration and may explain how nerve damage lead

127 scaffolds may see versatile applications in nerve regeneration and neural engineering.

128 f the molecular and cellular determinants of nerve regeneration and neuropathic pain in humans.

129 ddition, there appear to be abnormalities of nerve regeneration and of sodium and calcium channels.

130 on (DRG) neurons may play different roles in nerve regeneration and pain.

131 ies are prevalent, yet strategies to improve nerve regeneration and prevent neurological disabilities

132 S) prior to nerve repair surgery accelerates nerve regeneration and promotes sensorimotor recovery.

133 tin as a novel therapeutic target to augment nerve regeneration and provide a workflow template by wh

134 s, PTEN deletion positively regulated facial nerve regeneration and recovery of whisker movement afte

135 d corneas, diabetes markedly delayed sensory nerve regeneration and reduced the number of infiltratin

136 However, nerve regeneration and remyelination are both perturbed,

137 The maturation of MPC activates nerve regeneration and restores functional motor units.

138 ffects of chronic denervation (CD) injury on nerve regeneration and resulting motor function.

139 xpression significantly disrupted peripheral nerve regeneration and subsequent neuromuscular junction

140 a significant increase in corneal epithelial nerve regeneration and substance P-positive nerve densit

141 for Apobec proteins during retina and optic nerve regeneration and suggest DNA demethylation may und

142 6a and KLF7a as important mediators of optic nerve regeneration and suggest that not all induced gene

143 eal such ulcers may include the promotion of nerve regeneration and survival of epithelial progenitor

144 plays function-conducive roles in peripheral nerve regeneration and synaptic plasticity.

145 , the identification of signals that control nerve regeneration and the cellular events they induce i

146 ed sciatic nerve greatly enhance the rate of nerve regeneration and the restoration of nerve function

147 te nervous niche may exert axon guidance and nerve regeneration and thus contribute to the stability

148 C10 to accelerate optic nerve and peripheral nerve regeneration and to enable spinal cord axon regene

149 cal treatment with PEDF+DHA promotes corneal nerve regeneration and wound healing in diabetic mice an

150 dormant functions of Schwann cells aimed at nerve regeneration and wound healing.

151 ed sympathetic innervation, promoted sensory nerve regeneration, and alleviated disease.

152 ellularized designer conduits for peripheral nerve regeneration, and could lead to the development of

153 tivity, is anti-angiogenic, promotes corneal nerve regeneration, and induces cell survival.

154 ated CNTs improved biocompatibility, induced nerve regeneration, and inhibited foreign-body reactions

155 ch artemin could influence bladder function, nerve regeneration, and pain, and provide a strong micro

156 tributing to both Wallerian degeneration and nerve regeneration, and their function has recently been

157 icrobial therapy, drug delivery, biosensors, nerve regeneration, and tissue engineering.

158 e medicine, including optogenetics and optic nerve regeneration; and diagnostics (minimally invasive

159 Olfactory nerve regeneration appears to be a useful in vivo model

160 treated animals demonstrated enhanced median nerve regeneration as measured by axon density (p < 0.00

161 density tended to be the most effective for nerve regeneration as measured by both histological axon

162 e beneficial effects in promoting peripheral nerve regeneration, as quantified by increased total mus

163 Focal nerve regeneration at the sites of radiofrequency ablati

164 t induction of Socs3 and Sfpq inhibits optic nerve regeneration but does not block it.

165 ganglion cells (RGCs) promotes potent optic nerve regeneration, but only a small population of Pten-

166 d (DHA), has been shown to stimulate corneal nerve regeneration, but the mechanisms involved are uncl

167 ssary for transgene reinduction during optic nerve regeneration, but were not as important for transg

168 iated NPD1 synthesis is suggested to precede nerve regeneration by demonstration of its accumulation

169 down fidgetin from rat neurons, which coaxes nerve regeneration by elevating microtubule mass in thei

170 t study sheds light on the mechanism of pulp nerve regeneration by identifying C5L2 as a negative reg

171 We conclude that ATF3 contributes to nerve regeneration by increasing the intrinsic growth st

172 ng treatments to alleviate the inhibition of nerve regeneration by repulsive factors.

173 We recently reported that nerve regeneration can be accelerated by axonal G3BP1 gr

174 Our understanding of nerve regeneration can be enhanced by delineating its un

175 te form of beta(1, 3)-glucan] promotes optic nerve regeneration comparable to zymosan in WT mice, but

176 However, despite significant nerve regeneration, corneal nerve density does not recov

177 Even a modest improvement in nerve regeneration could have significant clinical impli

178 orneal sensitivity in most of them thanks to nerve regeneration documented by IVCM.

179 s to halt or reverse nerve damage or promote nerve regeneration, early diagnosis of diabetic polyneur

180 the extrinsic cues available in the natural nerve regeneration environment.

181 rentiate into a variety of cells and secrete nerve regeneration factors have become an emerging optio

182 rentiate into a variety of cells and secrete nerve regeneration factors.

183 fer for histomorphometric analysis of median nerve regeneration, flexor digitorum superficialis atrop

184 systemic MSC treatment resulted in improved nerve regeneration following allogeneic hindlimb transpl

185 the hypothesis that ES would enhance sensory nerve regeneration following digital nerve transection c

186 of axons, a vital requirement for successful nerve regeneration following injury.

187 nd repair, and promote axon growth and local nerve regeneration following injury.

188 phage specification was essential for proper nerve regeneration following injury.

189 ry and, after local administration, enhances nerve regeneration following nerve crush.

190 crophages have been implicated in peripheral nerve regeneration for some time, supposedly through the

191 ls (DPSCs) appear to be a good candidate for nerve regeneration given their accessibility, neural cre

192 Peripheral nerve regeneration has been studied extensively, with pa

193 nges in gene expression that accompany optic nerve regeneration has led to the identification of prot

194 However, the potential for PLL nerve regeneration has not been tested yet beyond the ea

195 ap, but the role of these molecules in optic nerve regeneration has not been well studied.

196 docosahexaenoic acid (DHA) promotes corneal nerve regeneration; here, we report the mechanism involv

197 atin remodeler CCCTC-binding factor impaired nerve regeneration, implicating chromatin organization i

198 n with docosahexaenoic acid (DHA) on corneal nerve regeneration in a mouse model of diabetes with or

199 tch in Sema3A's function toward induction of nerve regeneration in adult murine corneas and in cultur

200 GC development, promotes long-distance optic nerve regeneration in adult rats of both sexes.

201 on (ES) has been shown to enhance peripheral nerve regeneration in animal models following axotomy an

202 or several ocular diseases and induces optic nerve regeneration in animal models.

203 A thorough understanding of nerve regeneration in Caenorhabditis elegans requires pe

204 best suited to study functional outcome and nerve regeneration in CTA.

205 only identified mechanisms underlying optic nerve regeneration in fish but also suggest new molecula

206 ld-type macrophages ameliorated the impaired nerve regeneration in macrophage-selective MCT1-null mic

207 st new molecular targets for enhancing optic nerve regeneration in mammals.

208 s an efficient strategy to measure and study nerve regeneration in man.

209 logical blockade of RAGE impaired peripheral nerve regeneration in mice subjected to RAGE blockade an

210 ent complement C5a receptor (C5aR) in dental nerve regeneration in regards to local secretion of nerv

211 To assess the potential role of nerve regeneration in restoring urinary tract function,

212 estosterone propionate (TP), augments facial nerve regeneration in the adult hamster.

213 During nerve regeneration in the adult, the expression of these

214 a therapeutic target to promote sympathetic nerve regeneration in the cardiac scar and reduce post-M

215 We first confirmed that PEDF + DHA increased nerve regeneration in the mouse cornea.

216 ty could provide new strategies to stimulate nerve regeneration in the PNS, fine control of mTOR acti

217 Hence, eNG and rNG can enhance nerve regeneration in the same way as isografts.

218 aims to investigate the role of C5L2 in pulp nerve regeneration in the secretion of BDNF by pulp fibr

219 n normal corneas, exogenous CNTF accelerated nerve regeneration in the wounded corneas of diabetic mi

220 Teleost fish show a remarkable capability of nerve regeneration in their CNS, while injuries to axon

221 y to be an important regulator of peripheral nerve regeneration in vitro and in vivo, but as determin

222 Here, we show that optic nerve regeneration in vivo correlates with Schwann cell-

223 Ralpha1 is dispensable for organogenesis and nerve regeneration in vivo, indicating that trans-signal

224 -GFP) stimulated axonal sprouting and facial nerve regeneration in vivo.

225 by MAG and that spermidine can promote optic nerve regeneration in vivo.

226 using thy1-YFP mice as a model for studying nerve regeneration in vivo.

227 tion of neural circuits in vitro, as well as nerve regeneration in vivo.

228 ection of nerve growth in vitro, and promote nerve regeneration in vivo.

229 rons, where it may play an important role in nerve regeneration in vivo.

230 nerve injury and these mice show accelerated nerve regeneration in vivo.

231 ort that Jak/Stat signaling stimulates optic nerve regeneration in zebrafish.

232 with mRNAs involved in injury responses and nerve regeneration, including importin beta1 (KPNB1) and

233 complete and research to enhance peripheral nerve regeneration is clinically important.

234 Peripheral nerve regeneration is dependent on the ability of regene

235 Previous studies indicate that nerve regeneration is hampered by activation of RhoA/ROC

236 Together, these results show that olfactory nerve regeneration is significantly slower in KO mice as

237 matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibros

238 In vivo, VEGF-B is required for normal nerve regeneration: mice lacking VEGF-B showed impaired

239 evelop and validate a standardized cutaneous nerve regeneration model and to define the rate of epide

240 ts the hypothesis that augmented sympathetic nerve regeneration (nerve sprouting) increases the proba

241 thology, and an in-depth look into augmented nerve regeneration, nerve guidance conduits, and drug de

242 on method that allows reliable evaluation of nerve regeneration, neural angiogenesis, muscle atrophy,

243 ent of different gene regulatory networks in nerve regeneration, neuronal cell death and neuropathy i

244 During Xenopus laevis optic nerve regeneration, NF subunit composition undergoes pro

245 he mechanisms responsible for the more rapid nerve regeneration observed after a previous (conditioni

246 HFtUS may quantify early peripheral nerve regeneration offering a window of opportunity for

247 Peripheral nerve regeneration often remains incomplete, due to an i

248 ver time with genes previously implicated in nerve regeneration or plasticity, we found a gene cluste

249 reated animals had significantly accelerated nerve regeneration (p < 0.001), increased walking speed,

250 the role of the PA system during peripheral nerve regeneration, PA-dependent activity as well as rec

251 ehensive, in-depth perspective on peripheral nerve regeneration, particularly nerve guidance conduits

252 on of peripheral nerve as well as regulating nerve regeneration pathways in vivo.

253 hamber model was used to evaluate peripheral nerve regeneration (PNR) in streptozocin (STZ)-induced d

254 Misguided nerve regeneration, polyneuronal innervation, and cortic

255 BDNF production, which could accelerate the nerve regeneration process.

256 All female mice have a faster nerve regeneration rate than males.

257 Axonal outgrowth during peripheral nerve regeneration relies on the ability of growth cones

258 ely envelop the neuronal soma, contribute to nerve regeneration remains unexplored.

259 ecruitment of functional CH fibers following nerve regeneration requires enhanced TRPV1 levels.

260 VEGF-B treatment increased nerve regeneration, sensation recovery, and trophic func

261 e made to reconstruct a permissive niche for nerve regeneration, solely using a living cell material

262 The clinical use of SCs in nerve regeneration strategies is hindered by the necessi

263 Nerve regeneration studies at the neuromuscular junction

264 However, nerve regeneration studies require long-term recovery of

265 rm hospital" allows us to perform the entire nerve regeneration studies, including on-chip axotomy, p

266 ans has opened new opportunities for in vivo nerve regeneration studies.

267 that exhibit an intrinsic capacity for optic nerve regeneration, such as zebrafish, remains unknown.

268 GCs) individually promoted significant optic nerve regeneration, such regrowth tapered off around 2 w

269 hindpaw skin and L2/L3 DRGs after saphenous nerve regeneration suggested that inhibition of the pote

270 l role in physiological processes, including nerve regeneration, synaptic function, and behavior.

271 Although compensation for some nerve regeneration takes place, the alterations in the s

272 Limitations in current nerve regeneration techniques have stimulated the develo

273 that a favorable environment is critical for nerve regeneration, the complex cellular interactions be

274 Despite recent advancements in peripheral nerve regeneration, the creation of nerve conduits with

275 After two distinct patterns of nerve regeneration, the subbasal nerves recovered to 65%

276 CSPGs inhibit nerve regeneration through receptor protein tyrosine pho

277 Axonally synthesized proteins support nerve regeneration through retrograde signaling and loca

278 his precise surgical technique should enable nerve regeneration to be studied in vivo in its most evo

279 pothesize that CES prior to DNT will promote nerve regeneration to restore ankle dorsiflexion.

280 ed GSK3 activity showed markedly accelerated nerve regeneration upon injury.

281 e estrogen receptor modulator, on peripheral nerve regeneration, using a model of sciatic nerve crush

282 se findings suggest that Fn14 contributes to nerve regeneration via a Rac1 GTPase-dependent mechanism

283 nal ganglion cells in the CNS promoted optic nerve regeneration via both histone methylation-dependen

284 ck-in mice reportedly accelerates peripheral nerve regeneration via increased MAP1B phosphorylation a

285 Post-wound nerve regeneration was also delayed in the DC-depleted c

286 Similarly, optic nerve regeneration was completely unaffected, although r

287 Nerve regeneration was enhanced by treadmill training po

288 The rate of peripheral nerve regeneration was enhanced in the transgenic mice t

289 tional importance of OPN and CLU, peripheral nerve regeneration was examined in OPN and CLU(-/-) mice

290 ologic sex, and their association to corneal nerve regeneration was identified.

291 ontribution of acute inflammation to sensory nerve regeneration was investigated in the murine cornea

292 Focal terminal nerve regeneration was observed only at the sites of abl

293 tudy shows that lens injury-stimulated optic nerve regeneration was significantly compromised in thes

294 well established model of postcrush sciatic nerve regeneration was used to test the hypothesis that

295 To identify genes involved in successful nerve regeneration, we analyzed gene expression in zebra

296 ndly, using our techniques, reduced rates of nerve regeneration were found in people with diabetes wi

297 onal mechanism linking C5aR and C5L2 in pulp nerve regeneration, which may be useful in future dentin

298 rimotor functions are restored by peripheral nerve regeneration with greater success following injuri

299 T/A) in GSK3(S/A) RGCs further boosted optic nerve regeneration, with axons reaching the optic chiasm

300 ect, which is a model for composite bone and nerve regeneration, with both models avoiding involvemen