ライフサイエンスコーパス: neural cell

1 modating the protracted development of human neural cells.

2 l conditions and determine the fate of other neural cells.

3 ne kinase physiologically expressed by fetal neural cells.

4 2 that is synthesized by cyclooxygenase 2 in neural cells.

5 s essential for the survival and function of neural cells.

6 ouse embryonic stem cells and differentiated neural cells.

7 ost potent inducer of GOT gene expression in neural cells.

8 ndiscriminately killed both tumor and normal neural cells.

9 les of the responding resident and recruited neural cells.

10 ticular form of "forefront" signaling in non-neural cells.

11 tion-induced caspase-3 activity in different neural cells.

12 RNA from human pluripotent stem cell-derived neural cells.

13 than in NDEs from cultured rat type-specific neural cells.

14 in a significant diminution in the number of neural cells.

15 eferentially binds long transcripts in human neural cells.

16 Trx1 are localized mainly in the nucleus of neural cells.

17 orate the surface of distinct populations of neural cells.

18 m mouse pluripotent cells and differentiated neural cells.

19 iferating NSCs can differentiate into mature neural cells.

20 -dense mitochondria in nGD cerebral cortical neural cells.

21 in the absence of the respective paralog in neural cells.

22 y benefit or harm surrounding neural and non-neural cells.

23 directs the growth of neurites in developing neural cells.

24 -) currents and taurine release in human non-neural cells.

25 body plan characterized by a small number of neural cells.

26 re detected in nGD brains and in CBE-treated neural cells.

27 regulated flow of energy equivalents between neural cells.

28 t combinations of Hdac1 and Hdac2 alleles in neural cells.

29 of the first genetic markers of postmitotic neural cells.

30 rfaces to form intertwined associations with neural cells.

31 spliced after NOVA2 downregulation in human neural cells.

32 hertz (GHz) ultrasonic stimulus to the human neural cells.

33 these sites show increased editing in adult neural cells.

34 Cas9 system to repress PTEN transcription in neural cells.

35 is, without affecting body patterning or non-neural cells.

36 -derived human-induced pluripotent stem cell neural cells.

37 nced monocyte-mediated ZIKV dissemination to neural cells.

38 factors required for ZIKV infection of human neural cells.

39 rons, glia, undifferentiated neurons and non-neural cells.

40 anism of glucocorticoid action is present in neural cells.

41 duced ER stress response and cytotoxicity in neural cells.

42 have potential as a regenerative therapy for neural cells.

43 date the study of virus-host interactions in neural cells.

44 wn receptors for MeV that are not present on neural cells.

45 embedded with osteoprogenitor, vascular, and neural cells.

46 te transmigration and viral dissemination to neural cells.

47 neural cultures are ubiquitous for studying neural cells, 3D cultures can more accurately replicate

48 populations of progenitor, neuronal, and non-neural cells across our differentiation time course.

49 n a very restricted set of genes involved in neural cell adhesion and synapse function.

50 A novel electrochemical sensor for a neural cell adhesion molecule (CD56) was constructed by

51 Since neural cell adhesion molecule (NCAM) activates FGF recep

52 The neural cell adhesion molecule (NCAM) and the receptor ty

53 The function of neural cell adhesion molecule (NCAM) expression in motor

54 sed axon defasciculation, but did not affect Neural Cell Adhesion Molecule (NCAM) expression or Schwa

55 The neural cell adhesion molecule (NCAM) is the major carrie

56 The Neural cell adhesion molecule (NCAM) plays an important

57 ysialic acid is a glycan modification of the neural cell adhesion molecule (NCAM) produced by the pol

58 polybasic region (PBR) that are required for neural cell adhesion molecule (NCAM) recognition and sub

59 As a modification of the neural cell adhesion molecule (NCAM), polySia is produce

60 Antibodies to these targets, including CD56/neural cell adhesion molecule (NCAM), promoted phagocyto

61 ighly variable inter-subject accumulation of neural cell adhesion molecule (NCAM)-positive myofibres,

62 tively charged glycan mainly attached to the neural cell adhesion molecule (NCAM).

63 We identified Neural Cell Adhesion Molecule (NCAM1) as a potential ZIK

64 that the neural cell adhesion molecule CD56 [neural cell adhesion molecule (NCAM1)] is specifically o

65 uded known schizophrenia risk genes, such as neural cell adhesion molecule (NRCAM) and calcium channe

66 The polysialylated form of the neural cell adhesion molecule (PSA-NCAM) functions broad

67 was dependent on Schwann cell expression of neural cell adhesion molecule 1 (NCAM1) and ultimately p

68 Neural cell adhesion molecule 1 (NCAM1; CD56) is express

69 Changes in expression of the neural cell adhesion molecule 2 (NCAM2) have been propos

70 (epithelial cell adhesion molecule [EpCAM], neural cell adhesion molecule [NCAM], epithelial growth

71 expression in the polysialylated form of the neural cell adhesion molecule and in perineuronal nets s

72 We have previously shown that the neural cell adhesion molecule CD56 [neural cell adhesion

73 ns potentially relevant to skin homeostasis: neural cell adhesion molecule L1 and dipeptidyl peptidas

74 Two proteins, the neural cell adhesion molecule L1 and dipeptidyl peptidas

75 cid (PSA) and its major protein carrier, the neural cell adhesion molecule NCAM, play important roles

76 These results together with those related to neural cell adhesion molecule polysialylation establish

77 Membrane-anchored PrP(C) and neural cell adhesion molecule were not required for S-Pr

78 thought to mediate rabies virus endocytosis (neural cell adhesion molecule, nicotinic acetylcholine r

79 t to the dermal lamina dynamically expresses neural cell adhesion molecule, tenascin-C, and other mol

80 Interestingly, besides the neural cell adhesion molecule, the polysialyltransferase

81 proteins, most commonly in the brain, on the neural cell adhesion molecule.

82 rtly by blocking adhesion mediated by the L1 neural cell adhesion molecule.

83 e modulation of polysialic acid (polySia) on neural cell adhesion molecules (NCAM).

84 Prominent family members are the neural cell adhesion molecules NCAM and L1, which were t

85 omodulators to the learning rate and linking neural cell adhesion molecules to memory maintenance.

86 ily of glycosylphosphatidylinositol-anchored neural cell adhesion molecules were identified and valid

87 enes are involved in synapse function and/or neural cell adhesion, with a substantial fraction also i

88 controlling apoptosis in immature noncycling neural cells after DNA damage.

89 They also protect neural cells against mitochondrial oxidative stress, sho

90 potent than natural flavonoids at protecting neural cells against oxidative stress and is capable of

91 ifferent in-register repeat mutants in human neural cells, all multimer-abolishing but no multimer-ne

92 ally expressed and homotypically enriched in neural cells along the neural/epidermal (Ne/Epi) boundar

93 notably, improper structural organization of neural cells and a lack of functional glia and vasculatu

94 om proliferating cells versus differentiated neural cells and applied to Illumina Human HT-12 v4 Expr

95 FMR1 targets include genes unique to human neural cells and associated with clinical phenotypes of

96 RF, was evaluated here for its expression in neural cells and brain.

97 in vitro, to lung-derived epithelial cells, neural cells and glial cells.

98 induced pluripotent stem cell (iPSC)-derived neural cells and have applied the method to measure amyl

99 family genes are expressed abundantly in the neural cells and have been suggested to play important r

100 verexpression of Srxn1 protects dopaminergic neural cells and human-induced pluripotent stem cell (hi

101 tabolism of glutamate was studied in primary neural cells and in stroke-affected C57-BL6 mice using m

102 ion program regulated by FoxP1 in both human neural cells and patient-relevant heterozygous Foxp1 mou

103 anges at the injury site, including death of neural cells and release of damage-associated molecular

104 ormal asymmetric cell division by developing neural cells and results in a massively enlarged brain c

105 brain homeostasis and the crosstalk between neural cells and the periphery.

106 ological excitable media, such as cardiac or neural cells and tissue, exhibit memory in which a chang

107 ted their bidirectional chemoattraction with neural cells, and more specifically, impaired unidirecti

108 EVs released from neural cells are implicated in synaptic plasticity, neur

109 h cells, immune cells, endothelial cells and neural cells are important regulatory components that se

110 However, our data also demonstrate that neural cells are much more tolerant of aneuploidy than e

111 ional changes downstream of EPO signaling in neural cells are not well understood.

112 notochord and floorplate cells, and ventral neural cells are patterned by the activities of Hh-regul

113 of the intestine, including mesenchymal and neural cells, are discussed.

114 llowed reimplantation of cultured autologous neural cells as a result of unknown trophic factors rele

115 ents within an experience are represented by neural cell assemblies firing at higher frequencies (gam

116 acid (PSA) which modulates NCAM functions of neural cells at the cell surface.

117 ition is a consequence of Cdk5 disruption in neural cells because remyelination in slice cultures is

118 Pelvic ganglia neural cell bodies contained heparanase 1, heparanase 2,

119 replicated well in BHK and undifferentiated neural cells but viruses with 14 or more Broccoli copies

120 so that the virus is impaired for infecting neural cells, but not epithelial cells, in vitro and is

121 now are examined in 2 distinct sets of human neural cells by quantification in astrocyte-derived exos

122 Neural cells can be derived either from pluripotent or a

123 an spectra in total), iPSCs and iPSC-derived neural cells can be distinguished by their intrinsic phe

124 rate that XIST RNA induced in differentiated neural cells can trigger chromosome-wide silencing of ch

125 ure nervous system, but its contributions to neural cell circuitry are largely uncharted.

126 eages and functions, including CNS intrinsic neural cells, CNS intrinsic nonneural cells, and CNS ext

127 mmunogenicity, led us to discover subsets of neural cells co-expressing the neural marker SOX2 and MH

128 "RDC-genes") that are long and have roles in neural cell communications and/or have been implicated i

129 to the brain, and reduced TH availability to neural cells could instead underlie the diseased phenoty

130 lating Alzheimer's disease pathology in a 3D neural cell culture model should also serve to facilitat

131 -beta and tau pathology in a single 3D human neural cell culture system.

132 ied a protocol for EV isolation from primary neural cell culture to collect EVs from frozen whole mur

133 differentiation, using two-dimensional human neural cell cultures and three-dimensional forebrain org

134 red temporal series of iPSC-derived in vitro neural cell cultures to endogenous brain tissue from the

135 for the generation and analysis of 3D human neural cell cultures, including the production of geneti

136 iary epithelial damage and regeneration, and neural cell damage.

137 stand the mechanisms of direct virus-induced neural-cell damage leading to demyelination and axonal l

138 inflammasome signalling results in decreased neural cell death both in response to DNA damage-inducin

139 in both human breast cancer and dopaminergic neural cells, demonstrating their potential for use in t

140 The present study compared neural cell density and serotonergic innervation of the

141 RNA-seq of neural cells depleted of ARGLU1 revealed significant cha

142 blasts, aortic artery endothelial cells, and neural cells derived from human embryonic stem cells.

143 TEN repression in human cell line models and neural cells derived from human iPSCs, and induced histo

144 Furthermore, patient neural cells derived from induced pluripotent stem cells

145 important mechanisms by which HCMV disturbs neural cell development in vitro.

146 rkA is known to induce neurite outgrowth and neural cell differentiation.

147 e immune signaling has also been observed in neural cells during development and disease, including i

148 culture for 7 weeks to create an autologous neural cell "ecosystem" and reimplanted bilaterally into

149 lso detected in primary cultures of cortical neural cells, especially astrocytes.

150 es.Following spinal injury in zebrafish, non-neural cells establish an extracellular matrix to promot

151 Immature neural cells established circuits that propagated electr

152 ffects of OA on alphaS homeostasis: in human neural cells, excess OA caused alphaS inclusion formatio

153 CSB-deficient neural cells exhibited increased sensitivity to DNA cros

154 In neural cells, exosome formation can be blocked by inhibi

155 Deficient neurotrophic factors of CSPG4-type neural cell exosomes in Alzheimer disease.

156 Enteric neural cells expressing the light-sensitive ion channel,

157 Neural cell fate acquisition is mediated by transcriptio

158 n nascent neuroectoderm directly links early neural cell fate acquisition with regulatory control of

159 of Tet1/2/3, displayed impaired adoption of neural cell fate and concomitantly skewed toward cardiac

160 results establish that PBX1 regulates adult neural cell fate determination in a manner beyond that o

161 1 levels will have important implications in neural cell fate development and disease.

162 gnaling thus acts as a rheostat to influence neural cell fate selection in both normal cortical devel

163 Neural cell fate specification is well understood in the

164 fied enrichment of binding sites for several neural cell fate-specifying transcription factors includ

165 g (SHH) and consequently altering SHH-guided neural cell-fate decisions.

166 p5e), ridge top (rdg), with expanded ventral neural cell fates at E10.5.

167 Our screen revealed molecules that influence neural cell fates, support the formation of a major conn

168 ecapitulated by differentiation of iPSC into neural cells followed by expression profiling and dissec

169 ipotent stem cells to obtain patient-derived neural cells for in vitro studies and as a source of cel

170 t the central complex evolved by integrating neural cells from an ancestral anterior neuroendocrine c

171 the microengineered capillary wall protected neural cells from plasma-induced toxicity.

172 inorelbine had been confirmed in assays with neural cells from the central and peripheral nervous sys

173 require immune responses that interfere with neural cell function and communication without affecting

174 hanism underlying the toxic effects of As on neural cell function and neurodevelopment and identifies

175 tions represent a delicate balance affecting neural cell functions in health and disease.

176 mpatibility complex (MHC)-matched allogeneic neural cell grafting in the brain, which is considered a

177 emonstrate the rationale for MHC-matching in neural cell grafting to the brain and its feasibility in

178 eported in some patients following embryonic neural cell grafts.

179 ease biology is to attempt to understand the neural-cell-immune interaction to investigate the underl

180 propagating wave of strong depolarization of neural cells, implicated in several neuropathological co

181 on of dopaminergic cells from other types of neural cells in a completely nondestructive manner.

182 of human pluripotent stem cell (PSC)-derived neural cells in animal models of neurological disease.

183 l help realize the potential of hPSC-derived neural cells in disease modeling and cell therapy.

184 By adapting optogenetics for use in non-neural cells in embryos, we show that developmentally pa

185 stingly, these protrusions contact different neural cells in the brain parenchyma including blood ves

186 subtype-specific neuronal fate of endogenous neural cells in the cerebral cortex as a function of ini

187 cetylcholine transporter (VAChT) in specific neural cells in the Ixodes synganglion.

188 te that cancer cells can fuse with bystander neural cells in the tumor microenvironment; and cancer c

189 fected animals and in infected human and rat neural cells in vitro The mechanism responsible for the

190 ExNef were rapidly taken up by neural cells in vitro, reducing the abundance of ABC tra

191 en the close relationship between HDAC11 and neural cells in vitro, we examined neural tissue in a pr

192 delivery, placement, and retention of viable neural cells in vivo.

193 the focus has widened to also include other neural cells including astrocytes, pericytes and endothe

194 stribution of both L1CAM and TrkA in various neural cells including neurons, their transcellular bind

195 using an interaction proteomics approach in neural cells including neurons, we uncover the brain-enr

196 mosaicism in early embryonic development and neural cells, including post-mitotic neurons.

197 nt, and individual RAN proteins are toxic to neural cells independent of RNA effects.

198 ls showed morphology of fully differentiated neural cells, indicating fusion between the cancer and n

199 us on the cytokines essential for immune and neural cell inflammatory responses and interactions.

200 importantly, the bioprinted constructs with neural cell integration facilitate rapid innervation and

201 In this study, we investigate the effects of neural cell integration into the bioprinted skeletal mus

202 s lay the neuroanatomical basis for tanycyte/neural cell interactions, which will be useful to furthe

203 port across the blood brain barrier and into neural cells is critical for normal cerebral physiologic

204 How ZIKV triggers this event in developing neural cells is not well understood at a molecular level

205 ns, as preventing dystroglycan expression in neural cells led to a similar set of BBB abnormalities a

206 city to phosphorylate intracellular Erk in a neural cell line.

207 roscopy (SCRM) platform was able to identify neural cell lineages derived from clinically relevant hu

208 lity tests were conducted using homogeneous, neural cell lines and heterogeneous, rat brain cells, re

209 Using a combination of neural cell lines, skin fibroblasts from AD patients, an

210 ell media routinely used for endothelial and neural cell lines.

211 permissive for HCMV infection, which causes neural cell loss and premature differentiation, thereby

212 hAFSCs co-localized with neural cell markers and expressed BDNF, TGF-beta1, GFAP,

213 ngs may help inform the development of human neural cell models for screening of potential therapeuti

214 litate the development of more precise human neural cell models of other neurodegenerative disorders.

215 e multiple rodent and human brain tissue and neural cell models to demonstrate that CLU is expressed

216 taneous Ca(2+) dynamics in cardiomyocyte and neural cell models.

217 aration of developmental pathways specifying neural cell morphology and ion channel expression.

218 stems than invertebrates, and an increase in neural cell number may have contributed to the sophistic

219 defects in axonal targeting and reduction in neural cell numbers.

220 dant extrachromosomal DNA in TREX1-deficient neural cells, of which endogenous Long Interspersed Elem

221 ne bound IL-6 receptor alpha (IL-6Ralpha) on neural cells, on peripheral nerves, on fine sensory affe

222 tional networks to regulate the diversity of neural cells originating from the SVZ.

223 Both immune and neural cells participate in this process, which requires

224 We show that IL-6Ralpha on neural cells, peripheral nerves, and fine sensory affere

225 Extracellular vesicles (EVs) released by neural cells play an essential role in brain homeostasis

226 nding/translocation domain was retargeted to neural cell populations by deleting its non-specific bin

227 thologies require the production of distinct neural cell populations from endogenous progenitor cells

228 change in progressively more differentiated neural cell populations in vivo.

229 Our analysis of neural cell populations revealed that Japanese macaques

230 natomical associations between tanycytes and neural cells present in the hypothalamic parenchyma, in

231 The neural cells produced by NMPs have spinal cord but not a

232 ein called Trithorax increases the number of neural cells produced from a single stem cell, in part b

233 velopment is characterized by rapid rates of neural cell proliferation and differentiation followed b

234 fine an important role for Cic in regulating neural cell proliferation and lineage specification, and

235 ls outside the brain induces upregulation of neural cell proliferation at long range.

236 GFAP+ astrocytes, but not in Nkx2.1-lineage neural cells, promoted diet-induced hyperphagia and obes

237 neurons generated from transplanted enteric neural cells provide a functional innervation of bowel s

238 , how the growth cone differs from other non-neural cells remains unclear.

239 toring clec-41 expression in adr-2 deficient neural cells rescued the chemotaxis defect, providing th

240 tor cells are subsequently differentiated in neural cells, resulting in a 3D neuronal construct with

241 mpared the chromosomal stability of over 500 neural cell samples from human and mouse with virtual ka

242 hy mutations in its transporters result in a neural cell-specific disorder remains unclear.

243 , and permanent integration of provirus into neural cells such as microglia and astrocytes.

244 Applying this approach to neural cell-surface molecules, we identify thousands of

245 ven by neural gene promoters for nestin (all neural cells), synapsin (neurons), or P0 (Schwann cells)

246 sulting in RSA59 (P), significantly affected neural cell syncytia formation and viral titers postinfe

247 nome, is highly expressed on the specialized neural cells that are uniquely found in adult sex segmen

248 has encountered unusual selective forces in neural cells that have driven them to acquire unique pos

249 , even when expressed far from the muscle or neural cells that mispattern.

250 n this review, we focus on the impact of non-neural cells that participate in the neurogenic niche, h

251 m cells (iPSCs), we generated MCT8-deficient neural cells that showed normal TH-dependent neuronal pr

252 In cultured wild-type brain cortical neural cells, the GCase-irreversible inhibitor, condurit

253 ay be possible to convert in vivo endogenous neural cells to a neuronal fate directly, providing an a

254 ha (HIFalpha) is a key regulator that adapts neural cells to physiological and pathologic hypoxic cue

255 ve transplantation strategies to provide new neural cells to promote the formation of new neuronal ne

256 raveled a remarkable propensity of primitive neural cells to self-organize into primitive patterns su

257 of CRISPR technologies to engineer isogenic neural cells to study the impact of common variants, and

258 /-)) leads to spontaneous differentiation of neural cells together with globally enhanced expression

259 Enteric neural cells transplanted into the bowel give rise to mu

260 These VP1 mutations may alter neural cell tropism or enable escape from neutralizing a

261 on-glial interactions and the role that each neural cell type plays in shaping adaptable neural circu

262 analysis of WGBS data to infer putative ARH neural cell types affected by the knockout, and to local

263 on constrains the generation of most retinal neural cell types and promotes a Muller glial cell fate

264 expanding protocols for generating different neural cell types and three-dimensional tissues, but the

265 Several Hh-dependent ventral neural cell types are not specified in the mutant neural

266 ng human brain organoids comprised of mature neural cell types as a three-dimensional tissue substrat

267 ates a common set of targets among different neural cell types but also operates in a cell type-speci

268 , large-scale production of disease-relevant neural cell types in formats compatible with high-throug

269 y precise, noninvasive control over specific neural cell types in the deep brain would advance the st

270 cterize gene expression patterns in distinct neural cell types of the Drosophila visual system using

271 we present tables listing the various human neural cell types that can be generated and the neurolog

272 ual and practical guide to classification of neural cell types using single-cell gene expression prof

273 n cellular states that recapitulate distinct neural cell types, are influenced by the tumor microenvi

274 eliant on Sox2/Pax6 cooperativity in several neural cell types.

275 ical function and utility for distinguishing neural cell types.

276 rrect spatiotemporal generation of different neural cell types.

277 is comprised of a vast diversity of distinct neural cell types.

278 erning, specification and differentiation of neural cell types.

279 whether INPs simply expand or also diversify neural cell types.

280 ion of almost all transcriptomically defined neural cell types.

281 respectively, in four functionally distinct neural cell types: induced pluripotent stem cell (iPSC)-

282 The results suggest the conditions of the neural cells under stress can be monitored.

283 Here we show that mouse neural cells undergo mediolaterally biased cell intercal

284 nd optimisation of representative imaging of neural cells using light-sheet and micro-endoscopic fluo

285 However, in differentiating neural cells we observed decreased expression of schizop

286 Primary rat neural cells were exposed to oxytocin before induction o

287 ith the age of the donors from which enteric neural cells were obtained.

288 aRNA-driven activation (RNAa) was limited to neural cells which normally express Foxg1 and did not hi

289 ces of prostate cancer cell interaction with neural cells, which are rich in the human prostate and r

290 ulating an IFN-gamma-dependent dialogue with neural cells, which maintains the effector function of t

291 tial to differentiate to unlimited number of neural cells, which provide powerful tools for neural re

292 the detection of other analytes secreted by neural cells, which would have the potential to open new

293 known to be phosphorylated by Cdk5 in chick neural cells while Grin1 has not been reported to be pho

294 SR100 to potently activate exon inclusion in neural cells while weakening 3' splice site recognition

295 protects against As-induced cytotoxicity in neural cells with concomitant suppression of As-induced

296 al transcription and alternative splicing in neural cells with consequences for glucocorticoid signal

297 Treatment of HCMV-infected neural cells with trehalose also inhibited production of

298 related to pluripotent, extra-embryonic, and neural cells, with each harboring multiple finer subpopu

299 ombinant human IgMs that bind to epitopes on neural cells, with the aim of treating neurological dise

300 specific ablation of immune, epithelial, or neural cells without off-target effects.