ライフサイエンスコーパス: neurodevelopmental

1 e critically involved in the pathogenesis of neurodevelopmental abnormalities and cognitive deficits

2 thers can display severe symptoms, including neurodevelopmental abnormalities and microcephaly.

3 ariants specifically recapitulates patients' neurodevelopmental abnormalities, including microcephaly

4 e human phenotype, including poor growth and neurodevelopmental abnormalities.

5 ller thalamic association nuclei represent a neurodevelopmental abnormality associated with psychosis

6 edisposition to anxiety disorders has both a neurodevelopmental and a genetic basis.

7 volvement of USP9X variants in a distinctive neurodevelopmental and behavioral syndrome in male subje

8 privation is associated with higher rates of neurodevelopmental and mental disorders in adulthood.

9 that can affect neurological function and/or neurodevelopmental and neurodegenerative conditions.

10 its promising therapeutic potential for many neurodevelopmental and neurodegenerative disorders as a

11 teins, as possible targets for therapies for neurodevelopmental and neurodegenerative disorders.

12 tes of SSBR, not DSBR, as the source of both neurodevelopmental and neurodegenerative pathology in PN

13 We further analyzed neurodevelopmental and neuronal properties, including ne

14 uronal communication (i.e., mutations effect neurodevelopmental and neurophysiological changes), and

15 dation pathways have been recently linked to neurodevelopmental and neuropsychiatric diseases, sugges

16 Neurodegenerative, neurodevelopmental and neuropsychiatric disorders are am

17 y synthesized polypeptides could explain the neurodevelopmental and neuropsychiatric disorders observ

18 se behaviors are disrupted in multiple human neurodevelopmental and neuropsychiatric disorders, such

19 he same genes are implicated across multiple neurodevelopmental and neuropsychiatric disorders, there

20 viduals who completed information on gender, neurodevelopmental and psychiatric diagnoses including a

21 e been reported in individuals with variable neurodevelopmental anomalies and non-specific facial fea

22 CNON cells are a good model of the neurodevelopmental aspects of schizophrenia and can be u

23 ly unaltered cellular model to elucidate the neurodevelopmental aspects of schizophrenia.

24 uloskeletal disorders (11% each); lymphatic, neurodevelopmental, cardiovascular, and hematologic diso

25 While translational theories link neurodevelopmental changes in threat learning to patholo

26 Joubert syndrome (JBTS) is a recessive neurodevelopmental ciliopathy characterized by a pathogn

27 early joint prediction of multiple abnormal neurodevelopmental (cognitive, language and motor) outco

28 subset of individuals from the Philadelphia Neurodevelopmental Cohort (PNC) completed two DWI scans

29 ts (293 with psychosis) and the Philadelphia Neurodevelopmental Cohort (PNC), consisting of 1,393 you

30 structural abnormalities in psychosis and a neurodevelopmental cohort, and to determine whether nucl

31 articipants were drawn from the Philadelphia Neurodevelopmental Cohort, including 712 youth with a li

32 s more pronounced for disorders with a clear neurodevelopmental component.

33 Helsmoortel-Van der Aa syndrome (HVDAS) is a neurodevelopmental condition associated with intellectua

34 22q11.2 deletion syndrome (22q11DS)-a neurodevelopmental condition caused by a hemizygous dele

35 c cause of autism spectrum disorder (ASD), a neurodevelopmental condition that currently has no speci

36 Autism spectrum disorder (ASD) is a neurodevelopmental condition with hallmark behavioral ma

37 Early-onset neurodevelopmental conditions (e.g., autism) affect male

38 Neurodevelopmental conditions commonly coexist in childr

39 spectrum disorders (ASD) refer to a range of neurodevelopmental conditions, which are genetically com

40 g some component of male-bias in early-onset neurodevelopmental conditions.

41 The goal of this study was to test the neurodevelopmental consequences of maternal e-cigarette

42 nfection in this model may have long-lasting neurodevelopmental consequences.

43 Exome sequencing of siblings with severe neurodevelopmental defects and clinical features of epil

44 ral stem/progenitor cell (NSPC) activity and neurodevelopmental defects are linked to intellectual di

45 findings provide a mechanistic insight into neurodevelopmental defects caused by maternal n-3 PUFAs

46 Mutations causing neurodevelopmental defects cluster in hotspots affecting

47 he molecular mechanisms by which METH causes neurodevelopmental defects have remained elusive.

48 lated polyamine metabolism contribute to the neurodevelopmental defects of Tsc2-RG mice, we used phar

49 To model neurodevelopmental defects, we engineered a mouse wherei

50 NA damage checkpoint kinase rescued Smc5 cKO neurodevelopmental defects.

51 e two-hit (immune plus neonatal HI) model of neurodevelopmental defects.SIGNIFICANCE STATEMENT In aut

52 nduced by genetic disorders with devastating neurodevelopmental deficiencies.

53 oursodeoxycholic acid improved metabolic and neurodevelopmental deficits and reversed leptin resistan

54 altered microtubule dynamics, with profound neurodevelopmental deficits.

55 s been causally linked to a constellation of neurodevelopmental deformities in the fetus resulting in

56 To estimate the number of neurodevelopmental delay areas in children across cognit

57 g evidence that de novo CNOT1 variants cause neurodevelopmental delay with a wide range of additional

58 ts in individuals ascertained to have severe neurodevelopmental delay, whereas 53 show higher frequen

59 ny prenatal environmental adversity on child neurodevelopmental delay.

60 hypothesis that CNOT1 impairment results in neurodevelopmental delay.

61 a major cause of childhood hearing loss and neurodevelopmental delay.

62 d a syndrome characterized by CDA and severe neurodevelopmental delay.

63 ive risk for higher number of areas of child neurodevelopmental delay.

64 e most frequent preventable birth defect and neurodevelopmental disability syndrome.

65 We identified a pediatric patient with neurodevelopmental disability, including autism traits,

66 in four unrelated individuals with profound neurodevelopmental disability, muscular hypotonia, feedi

67 Rett syndrome (RTT) is a severe neurodevelopmental disease caused by mutations in the me

68 ortical development, which are important for neurodevelopmental disease modeling.

69 human brain tissue in neurodegenerative and neurodevelopmental disease there are few similar data fo

70 Apart from CRSD, neurodevelopmental disease was observed in all affected

71 l-regulated protein kinase 2, ERK2), cause a neurodevelopmental disease within the RASopathy phenotyp

72 utations in NARS1 are a significant cause of neurodevelopmental disease, where the mechanism for de n

73 e, we have coupled multiplexed repression of neurodevelopmental disease-associated genes to single-ce

74 errant RNA metabolism in the pathogenesis of neurodevelopmental disease.

75 art disease, craniofacial malformations, and neurodevelopmental disease.

76 current copy number variants associated with neurodevelopmental disease.

77 ctrum disorders (ASD) are a group of related neurodevelopmental diseases displaying significant genet

78 hogenic variants in TRIO are associated with neurodevelopmental diseases, including intellectual disa

79 ion is linked to the pathogenesis of various neurodevelopmental diseases.

80 set of the data from the Province of Ontario Neurodevelopmental Disorder (POND) Network was used incl

81 Fragile X syndrome is a neurodevelopmental disorder associated with a broad rang

82 e 22q11.2 deletion syndrome (22q11.2DS) is a neurodevelopmental disorder associated with a number of

83 riants in SCAF4 are causative for a variable neurodevelopmental disorder associated with impaired mRN

84 romatosis type 1 (NF1) is a common monogenic neurodevelopmental disorder associated with physical and

85 Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by a mutation or dele

86 Rett syndrome is an incurable neurodevelopmental disorder caused by mutations in the g

87 it/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by age-inappro

88 Autism is a clinically heterogeneous neurodevelopmental disorder characterized by impaired so

89 Loss-of-function SYNGAP1 mutations cause a neurodevelopmental disorder characterized by intellectua

90 ift variants in NOVA2 affected with a severe neurodevelopmental disorder characterized by intellectua

91 Affected individuals demonstrated a variable neurodevelopmental disorder characterized by mild intell

92 reminiscent of human ocular motor apraxia, a neurodevelopmental disorder characterized by reduced sac

93 Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social comm

94 s complex (TSC) is a rare autosomal dominant neurodevelopmental disorder characterized by variable ex

95 ss-of-function variants in this gene cause a neurodevelopmental disorder defined by cognitive impairm

96 Angelman Syndrome (AS) is a severe neurodevelopmental disorder due to impaired expression o

97 Rett syndrome (RTT) is an X-linked dominant neurodevelopmental disorder due to pathogenic mutations

98 is in the initial indication of amblyopia, a neurodevelopmental disorder for which available treatmen

99 and therefore represents a strong candidate neurodevelopmental disorder gene.

100 Within these neurodevelopmental disorder genes, SLC6A1, which encodes

101 te cerebral palsy risk genes overlapped with neurodevelopmental disorder genes.

102 t variants in CAPZA2 lead to a non-syndromic neurodevelopmental disorder in children.

103 The neurodevelopmental disorder Rett syndrome is caused by m

104 ions in the MECP2 gene cause the progressive neurodevelopmental disorder Rett syndrome(3-5), which is

105 epressor protein MeCP2 cause the devastating neurodevelopmental disorder Rett syndrome.

106 spectrum disorder (ASD) is a multifactorial neurodevelopmental disorder that encompasses a complex a

107 n-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that is consistently associa

108 nia is still unknown, it is accepted to be a neurodevelopmental disorder that results from the intera

109 campal CA1, using a mouse model of the human neurodevelopmental disorder Type I Lissencephaly.

110 , as its loss leads to fragile X syndrome, a neurodevelopmental disorder which is the most prevalent

111 vity disorder (ADHD) is a severely impairing neurodevelopmental disorder with a prevalence of 5% in c

112 nd female Dravet syndrome (Scn1a+/-) mice, a neurodevelopmental disorder with prominent temperature-s

113 critical role in the pathogenicity of human neurodevelopmental disorder.

114 disease-modifying treatment for a syndromic neurodevelopmental disorder.

115 Schizophrenia (SCZ) is a neurodevelopmental disorder.

116 phenotypically and genetically heterogeneous neurodevelopmental disorder.

117 eterious CDK19 variants underlie a syndromic neurodevelopmental disorder.

118 velopmental syndrome, termed syt1-associated neurodevelopmental disorder.

119 r association to Rett Syndrome (RTT), a rare neurodevelopmental disorder.

120 nting, causes Angelman syndrome (AS), a rare neurodevelopmental disorder.

121 show that ankyrin-G interacts with Usp9X, a neurodevelopmental-disorder-associated deubiquitinase (D

122 In the full dataset, genes associated with neurodevelopmental disorders (n = 159) were significantl

123 abits are risk factors for the occurrence of neurodevelopmental disorders (NDD).

124 ctivity disorder (ADHD), the entire range of neurodevelopmental disorders (NDDs) has not yet been wel

125 Most genes associated with neurodevelopmental disorders (NDDs) were identified with

126 arge number of genes have been implicated in neurodevelopmental disorders (NDDs), but their contribut

127 elated phenotypes into a broader category of neurodevelopmental disorders (NDDs).

128 re clinically and biologically heterogeneous neurodevelopmental disorders (NDDs).

129 ses (HMTs) are major contributing factors in neurodevelopmental disorders (NDDs).

130 Nevertheless, the etiology of these neurodevelopmental disorders and histamine's role in the

131 ive Pol III mutations have been described in neurodevelopmental disorders and hypersensitivity to vir

132 TOR pathway genes are linked to a variety of neurodevelopmental disorders and malformations of cortic

133 sm spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs new therapeutic a

134 inked to synapse pathologies associated with neurodevelopmental disorders and neurodegenerative disea

135 omosomal locus are associated with syndromic neurodevelopmental disorders and reciprocal physiologica

136 A large fraction of rare and severe neurodevelopmental disorders are caused by sporadic de n

137 Many neurodevelopmental disorders are characterized by impair

138 However, it is unclear how genetic risks for neurodevelopmental disorders are translated into spatial

139 These results suggest that neurodevelopmental disorders arising from NMDAR deficien

140 ses understanding of the complex etiology of neurodevelopmental disorders arising from rare missense

141 nces of 101 known de novo variant-associated neurodevelopmental disorders as well as 3106 putative mo

142 ne duplication in KIF21B in individuals with neurodevelopmental disorders associated with brain malfo

143 the vast majority of these de novo monogenic neurodevelopmental disorders because of phenotypic heter

144 ortical neuroimaging data from patients with neurodevelopmental disorders caused by genomic copy numb

145 tual disability disorders (SSRIDDs) are rare neurodevelopmental disorders characterized by developmen

146 Neurodevelopmental disorders have a heritable component

147 Some of them were candidates for neurodevelopmental disorders in humans including Nrg3, N

148 We compared an environmental model of neurodevelopmental disorders in which mice were exposed

149 pport a neuroimmune mechanism that underlies neurodevelopmental disorders in which the production of

150 STXBP1 are among the most frequent causes of neurodevelopmental disorders including intellectual disa

151 tion factor eEF1A2, have been shown to cause neurodevelopmental disorders including often severe epil

152 Neurodevelopmental disorders present with synaptic alter

153 ylating enzyme that has been associated with neurodevelopmental disorders primarily in female subject

154 n contrast, the involvement of USP9X in male neurodevelopmental disorders remains tentative.

155 nsight into the possible etiology underlying neurodevelopmental disorders resulting from histamine dy

156 uitry, and its disruption has been linked to neurodevelopmental disorders such as autism and schizoph

157 ynapses, and its disruption is implicated in neurodevelopmental disorders such as Phelan-McDermid syn

158 as been linked to complex disease, including neurodevelopmental disorders such as schizophrenia and a

159 the Kanizsa illusory contours is impaired in neurodevelopmental disorders such as schizophrenia, auti

160 sessive-compulsive disorder (OCD) are common neurodevelopmental disorders that frequently co-occur.

161 ormations of cortical development (MCDs) are neurodevelopmental disorders that result from abnormal d

162 l dysphagia-is often associated with several neurodevelopmental disorders that subsequently alter com

163 variant burden of NCKAP1 in individuals with neurodevelopmental disorders which needs further replica

164 or oligodendrocyte and myelin dysfunction in neurodevelopmental disorders with cognitive symptoms.

165 pectrum disorder (ASD) is a constellation of neurodevelopmental disorders with high phenotypic and ge

166 tism spectrum disorders (ASD) are a group of neurodevelopmental disorders with symptoms including soc

167 eficit and sleep disturbance across multiple neurodevelopmental disorders(6-9).

168 hedding light on the genetic architecture of neurodevelopmental disorders, and new approaches are rev

169 bellum is a key brain region in a variety of neurodevelopmental disorders, and the adult cerebellum h

170 only associated with schizophrenia and other neurodevelopmental disorders, but are also a contributin

171 genetic locus are associated with a range of neurodevelopmental disorders, including autism spectrum

172 twork connectivity, which has been linked to neurodevelopmental disorders, including autism spectrum

173 ild speech and language delay to intractable neurodevelopmental disorders, including but not limited

174 ss are implicated in the etiology of complex neurodevelopmental disorders, including schizophrenia, a

175 mented and cost-effective screening tool for neurodevelopmental disorders, particularly in cases when

176 ts in OCD are enriched for those reported in neurodevelopmental disorders, particularly Tourette's di

177 ng health issues, such as epilepsy and other neurodevelopmental disorders, sleep problems, and mental

178 (DNMs) are significant risk factors in many neurodevelopmental disorders, whereas schizophrenia (SCZ

179 ities to model and test therapies for severe neurodevelopmental disorders, while revealing significan

180 genes encoding synaptic proteins cause many neurodevelopmental disorders, with the majority affectin

181 n social dynamics and is impaired in several neurodevelopmental disorders.

182 ield a broad range of behavioral deficits in neurodevelopmental disorders.

183 tial opportunities for precision medicine in neurodevelopmental disorders.

184 em a potential key point of vulnerability in neurodevelopmental disorders.

185 these behaviors in many neuropsychiatric and neurodevelopmental disorders.

186 ure to endocrine disruptors and incidence of neurodevelopmental disorders.

187 s besides cancer, including lung, renal, and neurodevelopmental disorders.

188 hypofunction has been implicated in several neurodevelopmental disorders.

189 tic capacity are known to cause a variety of neurodevelopmental disorders.

190 ons toward understanding the pathogenesis of neurodevelopmental disorders.

191 including benign and malignant neoplasia and neurodevelopmental disorders.

192 g these genes in COS as well as in pediatric neurodevelopmental disorders.

193 ranscriptional dysregulation in co-occurring neurodevelopmental disorders.

194 cardiac anomalies, limb dysmorphologies and neurodevelopmental disorders.

195 n histone-modifying enzymes may cause severe neurodevelopmental disorders.

196 o determine the genetic aetiology underlying neurodevelopmental disorders.

197 nts affected genes which are associated with neurodevelopmental disorders.

198 on of this regulatory pathway contributes to neurodevelopmental disorders.

199 of de novo mutations associated with complex neurodevelopmental disorders.

200 ants (CNVs) have a higher risk of developing neurodevelopmental disorders.

201 promotes social behavior in mouse models of neurodevelopmental disorders.

202 vo mutations in SLC12A2 in six children with neurodevelopmental disorders.

203 nesis whose orthologs include risk genes for neurodevelopmental disorders.

204 Autism Spectrum Disorder (ASD) is a common neurodevelopmental disturbance afflicting a variety of f

205 tistically significant relationship with the neurodevelopmental domain and clinical domain, respectiv

206 rum of neurological pathologies ranging from neurodevelopmental dysfunction in microcephaly with earl

207 sions that can trigger neurodegeneration and neurodevelopmental dysfunction, respectively.

208 advancing our understanding of the variable neurodevelopmental effects induced by MIA and for biomar

209 not sufficiently sensitive to detect adverse neurodevelopmental effects of maternal and perinatal hyp

210 f cellular stress are generated during these neurodevelopmental events, all of which can potentially

211 Neurodevelopmental expression of ZDHHC14 mirrors that of

212 cally significantly associated with elevated neurodevelopmental, externalizing, and depressive sympto

213 opathology factor, and several dimensions of neurodevelopmental, externalizing, and internalizing sym

214 Neurodevelopmental functioning was compared in children

215 records, familial whole-exome sequences and neurodevelopmental gene expression patterns, we identifi

216 ate that MiDAC functions as a modulator of a neurodevelopmental gene expression program and binds to

217 signaling that ensures correct regulation of neurodevelopmental gene expression.

218 this atlas serves as a resource for decoding neurodevelopmental gene regulation in health and disease

219 Neurodevelopmental genes including autism candidates are

220 notyped for a selection of antioxidative and neurodevelopmental genes.

221 of death (16.2% and 15.0%, respectively) and neurodevelopmental impairment (39.6% and 40.3%, respecti

222 primary outcome was a composite of death or neurodevelopmental impairment (cognitive delay, cerebral

223 fects, especially the risk of causing severe neurodevelopmental impairment (sNDI).

224 bo group in the incidence of death or severe neurodevelopmental impairment at 2 years of age (97 chil

225 transfusion did not improve survival without neurodevelopmental impairment at 22 to 26 months of age,

226 The primary outcome was death or severe neurodevelopmental impairment at 22 to 26 months of post

227 age did not result in a lower risk of severe neurodevelopmental impairment or death at 2 years of age

228 Severe neurodevelopmental impairment was defined as severe cere

229 old group, 423 (50.1%) died or survived with neurodevelopmental impairment, as compared with 422 of 8

230 ncreased risk of lifelong disease, including neurodevelopmental impairment.

231 eks gestational age) remain at high risk for neurodevelopmental impairments.

232 oid and other cancers and/or autoimmunity or neurodevelopmental issues including autism spectrum diso

233 A key neurodevelopmental landmark is the excitatory to inhibit

234 Our work contributes to understanding the neurodevelopmental mechanisms that may be disturbed in t

235 ure research aiming to better understand the neurodevelopmental mechanisms underlying risk for psycho

236 A neurodevelopmental model traces the pathway from adverse

237 In vitro neurodevelopmental models seek to mimic these processes

238 in human induced pluripotent stem cell-based neurodevelopmental models to probe genetic risk in a cel

239 y affected SCZ-associated and ASD-associated neurodevelopmental modules, including loading highly ont

240 xplored this possibility in DYT1 dystonia, a neurodevelopmental movement disorder caused by a loss-of

241 We identified neurodevelopmental multimorbidity (>=2 of these conditio

242 le conditions may disadvantage children with neurodevelopmental multimorbidity, who we observed had s

243 0 clinical trials currently underway, across neurodevelopmental, neurodegenerative, muscular dystroph

244 five different categorical domains, namely, neurodevelopmental, neurometabolic and neurodegenerative

245 We propose designs for neurodevelopmental optimization research programs utiliz

246 measured soon after birth, predicts adverse neurodevelopmental outcome eighteen months after neonata

247 utic hypothermia (TH) improves the long-term neurodevelopmental outcome of neonates with moderate to

248 ent and have long-lasting adverse effects on neurodevelopmental outcome.

249 between early maturational trajectories and neurodevelopmental outcome.

250 The poor neurodevelopmental outcomes and persistence of ventricul

251 sources and role of cord UMFA in children's neurodevelopmental outcomes and underlying mechanisms.

252 It is unknown whether infant neurodevelopmental outcomes are also influenced by mater

253 This study reports 5-year neurodevelopmental outcomes for Swiss children born befo

254 However, effects on neurodevelopmental outcomes have not been established.

255 her aimed to link these in vitro findings to neurodevelopmental outcomes in children who were exposed

256 Neurodevelopmental outcomes were evaluated at 2 years of

257 look into etiology of described differences, neurodevelopmental outcomes, and role of the CC as an ea

258 Purpose To evaluate neurodevelopmental outcomes, gray matter volumes, and MR

259 s callosum (CC) as an important predictor of neurodevelopmental outcomes.

260 otic supplementation can improve offspring's neurodevelopmental outcomes.

261 Apparently, a broad range of neurodevelopmental pathologic mechanisms also target oro

262 olesterol metabolism are common hallmarks of neurodevelopmental pathologies.

263 l regulator of interneuron fate relevant for neurodevelopmental pathologies.This article has an assoc

264 s of the adult nervous system long after the neurodevelopmental period.

265 ntral innate immune system during a critical neurodevelopmental period.

266 licit memory of ambiguous threat, and inform neurodevelopmental perspectives on anxiety.

267 d a subgroup of patients with a non-dystonic neurodevelopmental phenotype.

268 Taken together, we report behavioral and neurodevelopmental phenotypes associated with Oga allele

269 tion and support the implication of SCAF4 in neurodevelopmental phenotypes.

270 Alterations to this fundamental neurodevelopmental process may contribute to the etiolog

271 o transcellular interactions that coordinate neurodevelopmental processes across developing neural ne

272 oach offers a powerful framework to identify neurodevelopmental processes affected by diverse risk va

273 stems within which they operate, 2) identify neurodevelopmental processes associated with polygenic r

274 Given the hypothesized role for early neurodevelopmental processes in these conditions, we her

275 bitors and can cause disruptions of critical neurodevelopmental processes, including neuronal electri

276 apse pruning with overlapping and concurrent neurodevelopmental processes, remains elusive.

277 ggest that events leading to deregulation of neurodevelopmental processes, such as inactivation of SH

278 ed synapse pruning in the context of complex neurodevelopmental processes.

279 is a crucial chromatin modifier in executing neurodevelopmental programs.

280 Schizophrenia is a severe neurodevelopmental psychiatric affliction manifested beh

281 ystem during pregnancy and increased risk of neurodevelopmental psychiatric conditions, such as schiz

282 tion as a potential therapeutic approach for neurodevelopmental psychiatric conditions.

283 has been associated with diseases including neurodevelopmental, psychiatric, and neurodegenerative d

284 with autism spectrum disorder (ASD) [45 with neurodevelopmental regression (NDR); 76% Male; mean (SD)

285 CMV) infection remains an important cause of neurodevelopmental sequelae in infants infected in utero

286 ncur that SOX6 haploinsufficiency leads to a neurodevelopmental SOXopathy that often includes ADHD an

287 orphological abnormalities reported at later neurodevelopmental stages.

288 l transcriptomic network, reminiscent of the neurodevelopmental state, and potentiation of rod - rod

289 ogically similar to adult PTSD, shows unique neurodevelopmental substrates that may impair recovery b

290 y lie at the basis of epileptic activity and neurodevelopmental symptoms in the patients.

291 icate that EIF2AK2 missense variants cause a neurodevelopmental syndrome that may share phenotypic an

292 family and the Notch signaling pathway in a neurodevelopmental syndrome with epilepsy, ptosis, and h

293 nge for many other TFs, including closure of neurodevelopmental TF binding sites and increased expres

294 Yet, the neurodevelopmental time course of these abnormalities re

295 These findings further our understanding of neurodevelopmental trajectories in TS and carry implicat

296 on between genetic and epigenetic control of neurodevelopmental trajectories.

297 of 14 and 19 suggests a potential 'aberrant' neurodevelopmental trajectory for critical limbic areas.

298 SRPK has acquired the capacity to control a neurodevelopmental ubiquitin signaling pathway.

299 We discuss neurodevelopmental underpinnings of psychosis spectrum s

300 ced pluripotent stem cells to replicate this neurodevelopmental window.