ライフサイエンスコーパス: neurokinin A

1 erived neuropeptides such as substance P and neurokinin A.

2 ncodes substance P and a related tachykinin, neurokinin A.

3 ion and nuclear translocation in response to neurokinin A.

4 roM), whereas responses to concentrations of neurokinin A (10 nM), neurokinin B (0.1 microM), substan

5 or an NK(3) tachykinin receptor antagonist (Neurokinin A 4-10; 100 nM to 5 microM).

6 Neurokinin A also activates NK1R, but leads to selective

7 duced by 10 microM acetylcholine, 0.1 microM neurokinin A and 70 mM potassium.

8 achykinin peptides include substance P (SP), neurokinin A and neurokinin B, which interact with three

9 ance P, serotonin, gamma-amino-butyric acid, neurokinins A and B, neurotensin, neuropeptide Y, peptid

10 (50) values were determined for substance P, neurokinin A, and galanin and were found to correspond w

11 Substance P, neurokinin A, and galanin were labeled with Cy5 and were

12 ogues of SP, and the NK-2 endogenous ligand, neurokinin A, and is coupled to the phospholipase C path

13 f neuropeptides, which includes substance P, neurokinin A, and neurokinin B, have three distinct rece

14 of neuropeptides including substance P (SP), neurokinin A, and neurokinin B, which are recognized for

15 binding of the three peptides, substance P, neurokinin A, and propionyl[Met(O(2))(11)]SP(7-11), to t

16 er of labeled neurons containing Substance P/Neurokinin A (approximately 20% of total labeled neurons

17 pigs, few stained positively for Substance P/Neurokinin A (approximately 3% of total labeled neurons)

18 Substance P and neurokinin A are closely related neuropeptides belonging

19 related neurokinin peptides, substance P and neurokinin A, are found in abundance within the substant

20 reprotachykinin A gene, which encodes SP and neurokinin A, are resistant to kainate excitoxicity.

21 [beta-Ala8]Neurokinin A ([beta-Ala8]NKA; 10 nM), an NK-2 selective

22 Substance P and neurokinin A bind to the reconstituted receptor in a bip

23 lockade of the facilitation of the reflex by neurokinin A but not substance P in normal rats.

24 these studies indicated that substance P and neurokinin A can directly induce nerve growth factor mRN

25 th Sendai virus on the number of Substance P/Neurokinin A-containing vagal afferent neurons whose cel

26 Phe7]neurokinin B > senktide > substance P = neurokinin A > neurokinin B.

27 The role of endogenous neurokinin A in changes in the excitability of spinal ne

28 uge NANCi responses, TSM was contracted with neurokinin A in the presence of atropine, propranolol, a

29 These results indicate that endogenous neurokinin A increases the excitability of spinal neuron

30 s from peripheral release of substance P and neurokinin A, is almost absent in the mutant mice.

31 unattainable because its endogenous ligand, neurokinin A, is short-lived and lacks receptor specific

32 Modulation of neurokinin A levels may also be related to the effect of

33 ceptors were able to bind to substance P and neurokinin A ligand with similar affinities; however, th

34 ll mice are caused by the extinction of a SP/neurokinin A-mediated signaling pathway that is activate

35 , Lys-bradykinin, Lys-(des-Arg9)-bradykinin, neurokinin A, Met-Lys-bradykinin, histatin 8, and a myos

36 er naturally occurring tachykinins including neurokinin A, neuropeptide K, neuropeptide gamma, eledoi

37 such as neuropeptides, substance P (SP), and neurokinin A (NK-A), which mediate hematopoietic stimula

38 Substance P (SP) and neurokinin-A (NK-A) are derived from the preprotachykini

39 f neuropeptides, including substance P (SP), neurokinin A (NKA), and neurokinin B (NKB), that are enc

40 natural peptide ligands substance P (SP) and neurokinin A (NKA), respectively.

41 ch encodes the peptides substance P (SP) and neurokinin A (NKA).

42 uperfusion of different tachykinin agonists (neurokinins A (NKA) and B (NKB), SP, and senktide) gave

43 ently mediate the effects of substance P and neurokinin A on human versus rat DA neurons.

44 effect of the neuropeptides, substance P and neurokinin A, on nerve growth factor expression in human

45 served with application of either [beta-Ala8]neurokinin A or senktide, selective NK2 and NK3 receptor

46 s there were significantly fewer Substance P/Neurokinin A positive neurons in nodose ganglia from vir

47 tachykinin receptors (substance P receptor, neurokinin A receptor, and neurokinin B receptor).

48 the natural peptide ligands substance P and neurokinin A, respectively, and have been targets for dr

49 inese hamster ovary cells to substance P and neurokinin A, respectively.

50 Substance P and neurokinin A stimulated a rapid increase in intracellula

51 C1 (encoding the tachykinins substance P and neurokinin A) to be strongly activated by LP within the

52 ing of fluorescently labeled substance P and neurokinin A was tested on the human astrocytoma cell li

53 Despite its inability to respond to neurokinin A, we found that NK1-betaArr1 expression caus

54 Fluorescent and radiolabeled substance P and neurokinin A were internalized similarly by cells expres