ライフサイエンスコーパス: neuropeptide

1 evels of substance P (SP), a proinflammatory neuropeptide.

2 etect endogenous physiological levels of the neuropeptide.

3 s and this, in turn, controls the release of neuropeptides.

4 alled lethargus and is induced by somnogenic neuropeptides.

5 uired for the wake-promoting action of NLP-2 neuropeptides.

6 ressing various calcium-binding proteins and neuropeptides.

7 in the reaction with several amino acids and neuropeptides.

8 described regulation of these two orexigenic neuropeptides.

9 such as neurotransmitters, neurohormones and neuropeptides.

10 uctural hallmarks of bilaterian-wide NPY/NPF neuropeptides.

11 neurotransmitter receptors, ion channels and neuropeptides.

12 urons (LSt), which express galanin and other neuropeptides.

13 Dynorphin, an opioid neuropeptide abundant in the ventral pallidum, shows dif

14 mical-functional backdrop upon which several neuropeptides act within the NAc to modulate behavior, w

15 Amylin, a pancreatic hormone and neuropeptide, acts principally in the hindbrain to decre

16 ating polypeptide (PACAP, gene Adcyap1) is a neuropeptide and hormone thought to play a critical role

17 l effector, RIM1, as essential molecules for neuropeptide and neurotrophin release from dense-core ve

18 encode transcription factors, receptors and neuropeptides and constituted around 30% of striatal int

19 dopamine neurons, which can be regulated by neuropeptides and hormones, play a fundamental role in c

20 ity but fails to trigger efferent release of neuropeptides and neurogenic inflammation typically prod

21 Neuron-derived neuropeptides and neurotransmitters regulate immune cell

22 chemical or mechanical stimuli by releasing neuropeptides and neurotransmitters, implicating them as

23 in vivo interaction between stress-promoting neuropeptides and nociceptin (NOP) receptors in humans.

24 ion of interactions between stress-promoting neuropeptides and NOP in addictive disorders.

25 Regulated secretion of neuropeptides and peptide hormones by secretory granules

26 -type signalling, but orthologs of PrRP-type neuropeptides and sNPF/PrRP-type receptors were identifi

27 ystems, several homologous brain regions and neuropeptides and their receptors have been shown to pla

28 surrounding migraine, including the role of neuropeptides and their release from meningeal trigemina

29 lar codes that arise from neurotransmitters, neuropeptides and transcription factors are minimally re

30 late physiology and behaviour in animals are neuropeptides, and a few bioactive peptides have already

31 under selection with genome reorganization, neuropeptides, and energy mobilization.

32 or the use of multiple neurotransmitters and neuropeptides, and identify transcription factors expres

33 ariety of cytokines, inflammatory mediators, neuropeptides, and neurotransmitters appear to facilitat

34 man skin responds to numerous neurohormones, neuropeptides, and neurotransmitters that reach it via t

35 late the trafficking and packaging of native neuropeptides, and report stimulation-evoked neuropeptid

36 e set of neurotransmitters, neuromodulators, neuropeptides, and their receptors-the "chemoconnectome"

37 In addition, many expressed one or more neuropeptides, and two expressed glutamatergic markers.

38 Neuropeptides are an important class of signaling molecu

39 In addition to classical neurotransmitters, neuropeptides are emerging as modulators of complex beha

40 Neuropeptides are important for regulating numerous neur

41 How these neuropeptides are produced and involved in diverse funct

42 al fluid (CSF) concentration of the "social" neuropeptide arginine vasopressin (AVP) is significantly

43 The neuropeptide arginine vasopressin (AVP) plays significan

44 y organized network of neurotransmitters and neuropeptides, as well as genetic, epigenetic and hormon

45 ented protocol produces enhanced coverage of neuropeptides at 15 mum spatial resolution, which was co

46 neurotensin, an otherwise non-BBB-penetrant neuropeptide, at levels capable of modulating CREB signa

47 ferential prohormone processing and distinct neuropeptide-based compartmentalization of the retrocere

48 des in complex tissue extracts is not due to neuropeptides being below the detection limit but due to

49 s ASIC modulator known to date is the opioid neuropeptide big dynorphin (BigDyn).

50 DCVs package and release cargoes including neuropeptides, biogenic amines, and peptide hormones.

51 Here, we show that ILC2s expressed both the neuropeptide calcitonin gene-related peptide (CGRP) and

52 inflammatory pain, inhibited release of the neuropeptide calcitonin gene-related peptide (CGRP) from

53 gation has provided strong evidence that the neuropeptide calcitonin gene-related peptide (CGRP) has

54 varicose nerve fibers containing the sensory neuropeptides, calcitonin gene-related polypeptide, and

55 w the physiological responses regulated by a neuropeptide called kisspeptin have evolved.

56 Pharmacological experiments indicate that neuropeptides can effectively tune neuronal activity and

57 Because the sensory neuropeptide CGRP (calcitonin gene-related peptide) regu

58 Here we report the role of endogenous neuropeptide cholecystokinin (CCK), released from dentat

59 lation of TCs, which exclusively express the neuropeptide cholecystokinin (CCK), to two groups of spa

60 Such a neuropeptide circuit largely overlaps with the fruitless

61 Thus, our findings identify a CeA->BST CRF neuropeptide circuit that generates anxiety-like behavio

62 ssues; however, these studies did not detect neuropeptide complements in manners comparable to those

63 ill being able to distinguish differences in neuropeptide concentration.

64 Understanding the contribution of neuropeptide-containing neurons to variation in social b

65 ypothesis proposing an integral role for the neuropeptide-containing trigeminal nerve.

66 The stress neuropeptide corticotropin releasing factor (CRF) is anx

67 Here we report that the stress-associated neuropeptide corticotropin releasing factor (CRF) produc

68 ensor was developed for the detection of the neuropeptide Corticotropin Releasing Hormone (CRH) based

69 57BL/6J mice and the influence of the stress neuropeptide corticotropin-releasing factor (CRF) on the

70 sex differences in receptors for the stress neuropeptide, corticotropin-releasing factor (CRF), that

71 1 receptors and are acutely activated by the neuropeptide CRF that is released in response to salient

72 release and actions of the stress-activated neuropeptide, CRH, contribute to the deleterious effects

73 uropeptide precursors, and in some instances neuropeptides derived from these precursors were confirm

74 proved over the original method, with 56% of neuropeptides detected in 3 out of 3 replicate injection

75 RPamide neuropeptides dose-dependently activate the GnRH/AKH-lik

76 innate lymphocyte responses to alarmins and neuropeptides during type 2 innate immune responses.

77 cific duplication of a ShK-like2 ancestor, a neuropeptide-encoding gene, followed by diversification

78 Peptide hormones and neuropeptides encompass a large class of bioactive pepti

79 be useful for gaining a deeper profiling of neuropeptides, especially those in low abundance, in a v

80 quired in vivo for the expression of urp2, a neuropeptide expressed in CSF-cNs.

81 y muscles and a subset of neurons, including neuropeptide-expressing motor neurons.

82 1 activity promotes CO(2) escape by altering neuropeptide expression in the BAG CO(2) sensors.

83 , in turn, controls expression of orexigenic neuropeptide expression in the MBH.

84 ory mechanisms restricting BMP-induced FMRFa neuropeptide expression to Tv4-neurons.

85 ERK signaling directly impact wake-promoting neuropeptide expression, revealing a mechanism through w

86 rsal median neurons, inhibits the release of neuropeptide F (NPF), which regulates feeding behavior.

87 Here we identify an NPY/neuropeptide F (NPF)-related neuropeptide system in Caen

88 ion of Caenorhabditis elegans neuropeptide Y/neuropeptide F and serotonin that could aid in our under

89 Flies lacking Neuropeptide F display sleep-dependent memory even when

90 the evolutionary ortholog of neuropeptide Y/neuropeptide F in the nematode Caenorhabditis elegans, a

91 ns utilizing serotonin, GABA, ACh, and short neuropeptide F interact in the LC12 optic glomerulus.

92 he GABA receptor neurons downstream of short neuropeptide F precursor (sNPF) signaling.

93 ransmitter and likely expresses 5HT1A, short neuropeptide F receptor (sNPFR), and the resistant to di

94 Inhibition of Neuropeptide-F (NPF) activates germline caspases require

95 of vertebrate neuropeptide-Y (NPY) known as neuropeptide-F (NPF) have been identified in protostome

96 prolactin-releasing peptide (PrRP) and short neuropeptide-F (sNPF) have been identified as paralogs o

97 Both NLP-2 and NLP-22 belong to the RPamide neuropeptide family and share sequence similarities with

98 The endogenous neuropeptide FF (NPFF) and its two cognate G protein-cou

99 Neuropeptide FF (NPFF) is well-known for its roles in th

100 its two cognate G protein-coupled receptors, Neuropeptide FF Receptors 1 and 2 (NPFFR1 and NPFFR2), r

101 eurons expressing the receptors of different neuropeptides for itch, including gastrin-releasing pept

102 Upon activation, nociceptors release neuropeptides from their terminals that potently shape t

103 Research on neuropeptide function has advanced rapidly, yet there is

104 ilitate more comprehensive investigations of neuropeptide function in A. japonicus, here we have anal

105 ausal mechanism of this effect driven by the neuropeptide galanin from the main noradrenergic nucleus

106 The neuropeptide galanin has been implicated in stress-relat

107 tochondrial respiration, by the reproductive neuropeptide GnRH.

108 In addition to classical neurotransmitters, neuropeptides have emerged to modulate such complex beha

109 markers such as calcium binding proteins and neuropeptides, helped the identification of thalamic nuc

110 lly, we elucidate the modulatory role of the neuropeptide hormone oxytocin in motivating extraordinar

111 itiation and sheds light on the evolution of neuropeptide-hormone systems.

112 ly conduct molecules larger than most native neuropeptides (i.e., molecular weight [MW] up to, at lea

113 effect, this nsPCR strategy enables enhanced neuropeptide identification and visualization from compl

114 investigated the hypothesis that oxytocin, a neuropeptide implicated in social behavior, would normal

115 It also changed expression of neuropeptides implicated in the modulation of feeding as

116 Substance P (SP) is a tachykinin neuropeptide, implicated in the pathogenesis of various

117 ere, we demonstrate an essential role for Lk neuropeptide in metabolic regulation of sleep.

118 These data indicate that GRP is a neuropeptide in sensory neurons for non-histaminergic it

119 Nociceptin is an antistress neuropeptide in the brain that promotes resilience in an

120 identified the receptor (MIHR) for these MIH neuropeptides in Clytia using cell culture-based "deorph

121 limitation of mass spectrometry analyses of neuropeptides in complex tissue extracts is not due to n

122 ated with determination of orthology between neuropeptides in different taxa.

123 ermined and subsequently used to detect more neuropeptides in extracts from the brain and pericardial

124 lly characterized as orexigenic hypothalamic neuropeptides in mammals.

125 , the investigation of stress and antistress neuropeptides in this sample has the potential to inform

126 data to identify neuropeptide precursors and neuropeptides in this species.

127 ly resolved method to measure the release of neuropeptides in vivo.

128 hypocretin-a stimulatory and wake-promoting neuropeptide-in the lateral hypothalamus.

129 ABA neurotransmission is regulated by opioid neuropeptides, including dynorphin.

130 r expression of calcium-binding proteins and neuropeptides, including parvalbumin (PV), somatostatin

131 Neurotensin (NT), a gut hormone and neuropeptide, increases in circulation after bariatric s

132 lated topics, including the study of complex neuropeptide interactions within the CNS.

133 C level.SIGNIFICANCE STATEMENT Oxytocin is a neuropeptide involved in several functions ranging from

134 nd neuropeptide Y (NPY) are two hypothalamic neuropeptides involved in the regulation of feeding beha

135 Multiple neuropeptide-ir interneurons branched in ME4, connecting

136 y of two brain neurons expressing leucokinin neuropeptide is elevated in thirsty and hungry flies, an

137 ls to immune cells via neurotransmitters and neuropeptides is indispensable for effective immunity an

138 demonstrating the essential roles played by neuropeptides, it has proven challenging to use this inf

139 EM sleep, implicating the involvement of the neuropeptide itself.

140 levels of diffusible extracellular Abeta, a neuropeptide largely present in oligomeric form, rise by

141 The regulation of neuropeptide level at the site of release is essential f

142 Neurexophilins are secreted neuropeptide-like glycoproteins, and neurexophilin1 and

143 Its paralog, ShK-like2, is a neuropeptide localized to neurons and is involved in dev

144 Looking ahead, some of these neuropeptides may have effects that could be harnessed t

145 or vulnerability to stress may thus involve neuropeptide-mediated dendritic remodeling in BLA princi

146 but hypothalamic neurons that synthesize the neuropeptide melanin-concentrating hormone (MCH) are cla

147 agonized by femtomolar concentrations of the neuropeptide NAPVSIPQ (NAP), an active fragment of the a

148 ress reduced amounts of the receptor for the neuropeptide neuromedin B (NMB).

149 e mSCs transcribe an array of genes encoding neuropeptides, neuropeptide receptors, and other nerve-r

150 ateral hypothalamic area (LH) expressing the neuropeptide neurotensin (Nts) is critical for orchestra

151 lyses revealed that neurons positive for the neuropeptide neurotensin promote NREM sleep.

152 uch as hormones, proteins, immune molecules, neuropeptides, neurotransmitters, mRNA, and noncoding RN

153 c Ca(2+) increase and dendritic release of a neuropeptide NLP-12.

154 family and share sequence similarities with neuropeptides of the bilaterian GnRH, adipokinetic hormo

155 neurons, which leads to the release of their neuropeptide onto the muscles of the crop-a stomach-like

156 determined the mPFC neuronal plasticity and neuropeptide orexin signaling are critical circuit and n

157 ning-induced plasticity and signaling of the neuropeptide orexin within the mPFC mediates cue potenti

158 receptors OX(1) and OX(2), activated by the neuropeptides OX-A and OX-B, is firmly established as a

159 F concentrations of the structurally related neuropeptide, OXT.

160 Although the neuropeptide oxytocin (OT) is thought to regulate prosoc

161 The neuropeptide oxytocin (OXT) mediates its actions, includ

162 We also discuss how the neuropeptide oxytocin impacts these circuits and their d

163 The pituitary neuropeptide oxytocin promotes social behavior, and is a

164 The two hypothalamic neuropeptides oxytocin and melanin concentrating hormone

165 t therapeutic strategies have focused on the neuropeptides oxytocin and vasopressin(4-6), which regul

166 We focused on a prominent neuropeptide, oxytocin (OXT) in the zebrafish as an in v

167 Synaptic release of neuropeptides packaged in dense-core vesicles (DCVs) reg

168 How do neuropeptides participate in the classic neuroinflammato

169 critical role of the established sensory TRP-neuropeptide pathway in influencing cutaneous discomfort

170 Sixteen of these neurons secrete the neuropeptide Pdf and have been called 'master pacemakers

171 2 and a further subpopulation expressing the neuropeptide Pdyn.

172 de neuropeptide, SIFamide receptor (SIFa_R), neuropeptide pigment dispersing factor (PDF), and the in

173 l-lateral neurons (lLNvs), which release the neuropeptide pigment-dispersing factor (PDF).

174 Various neuropeptides play important roles in the regulation of

175 Various neuropeptides play important roles in the regulation of

176 Neuropeptides play pivotal roles in modulating circadian

177 rimental studies revealed that the PrRP-type neuropeptide pQDRSKAMQAERTGQLRRLNPRF-NH(2) is a potent l

178 a discovery that transcripts of one or more neuropeptide precursor (NPP) and one or more neuropeptid

179 ta enabled identification of the location of neuropeptide precursor genes on genomic scaffolds and li

180 Overexpression of neuropeptide precursor VGF in 5xFAD mice partially rescu

181 ether, more than 100 peptide signals from 15 neuropeptide-precursor genes could be traced with high s

182 sequence data and proteomic data to identify neuropeptide precursors and neuropeptides in this specie

183 The discovery of a large repertoire of neuropeptide precursors and neuropeptides provides a bas

184 We identified 44 transcripts encoding neuropeptide precursors or putative neuropeptide precurs

185 encoding neuropeptide precursors or putative neuropeptide precursors, and in some instances neuropept

186 n-concentrating hormone (MCH) is a conserved neuropeptide, predominantly located in the diencephalon

187 Mutants deficient in neuropeptide processing and secretion suppressed glial c

188 activated peptidergic nociceptors, which are neuropeptide-producing nociceptive sensory neurons that

189 The study of neuropeptides provided the first evidence that antisera

190 ge repertoire of neuropeptide precursors and neuropeptides provides a basis for experimental studies

191 preciated role for the relatively unexplored neuropeptide Pth2 in both tracking and responding to the

192 he gene that encodes the vertebrate-specific neuropeptide Pth2.

193 The neuropeptide receptor neuropeptide Y receptor type 1 (Np

194 ral circuit signals through peripheral NPR-4/neuropeptide receptor, SGK-1/serum- and glucocorticoid-i

195 Here, we identify two opposing neuropeptide/receptor signaling pathways: NLP-22 promote

196 be an array of genes encoding neuropeptides, neuropeptide receptors, and other nerve-related proteins

197 uped Clytia MIHR with a subset of bilaterian neuropeptide receptors, including neuropeptide Y, gonado

198 Neuromedin U (NmU) is a neuropeptide regulating diverse physiological processes.

199 tetrapods.SIGNIFICANCE STATEMENT Studies of neuropeptide regulation of vertebrate social behavior ha

200 gs in the mechanism of migraine, blockade of neuropeptide release by anti-migraine drugs, and activat

201 Neuropeptide release changes the dynamics of crop enlarg

202 neuropeptides, and report stimulation-evoked neuropeptide release events as real-time changes in fluo

203 Neuropeptide release in the brain has traditionally been

204 lines could be a viable method for detecting neuropeptide release in vitro, while still being able to

205 Ca(2+) However, the molecular regulation of neuropeptide release remains to be clarified.

206 Here we introduce Neuropeptide Release Reporters (NPRRs): novel geneticall

207 ince firing in bursts has been associated to neuropeptide release, we hypothesized that I(h) would be

208 temporal and spatial resolution of observing neuropeptide release.

209 Furthermore, we discovered that FLP-1 neuropeptide released from this olfactory neural circuit

210 ellyfish Clytia hemisphaerica, MIH comprises neuropeptides released from somatic cells of the gonad.

211 Amnesiac encodes a secreted neuropeptide required in the MB for two phases of aversi

212 the final steps in the biosynthesis of many neuropeptides requires a single enzyme, peptidylglycine

213 Release of neuropeptides requires long-lasting, high levels of cyto

214 neuropeptide precursor (NPP) and one or more neuropeptide-selective G-protein-coupled receptor (NP-GP

215 ically examined the associations of SIFamide neuropeptide, SIFamide receptor (SIFa_R), neuropeptide p

216 that investigate the physiological roles of neuropeptide signaling systems in A. japonicus.

217 GPCR pairs, implying the likelihood of local neuropeptide signaling.

218 very precise and local form of sex-specific neuropeptide signaling.

219 Neuropeptide signalling systems comprising peptide ligan

220 Our data suggest that the somnogenic NLP-22 neuropeptide signals through GNRR-6, and that both GNRR-

221 CeA, which are mainly those that express the neuropeptide somatostatin, send projections to the globu

222 these GPe-projecting CeA neurons express the neuropeptide somatostatin.

223 We also found that the neuropeptide substance P (SP), an endogenous agonist of

224 sensitization facilitates the release of the neuropeptide substance P from TRPM8(+) cold-sensing neur

225 bolished opioid-mediated depression, and the neuropeptide Substance P, but not blockade of inhibitory

226 ergen-activated sensory neurons released the neuropeptide Substance P, which stimulated proximally lo

227 ac1, the gene encoding the precursor for the neuropeptide substance P.

228 sient receptor potential (TRP)V1, TRPA1, and neuropeptides (substance P and calcitonin gene-related p

229 partly regulated by soluble factors, such as neuropeptides, substance P (SP), and neurokinin A (NK-A)

230 ve intestinal peptide (VIP) is a pleiotropic neuropeptide synthetized in trophoblasts at the maternal

231 identify an NPY/neuropeptide F (NPF)-related neuropeptide system in Caenorhabditis elegans and show t

232 Here we identify a neuropeptide system that becomes activated immediately a

233 erable research has focused on the role that neuropeptide systems and the amygdala play in mediating

234 ng calcitonin gene-related peptide (CGRP), a neuropeptide that modulates M cells and SFB levels to pr

235 Orexins are neuropeptides that activate the rhodopsin-like G protein

236 a leptin inhibitor); and Cart, Pomc and Npy (neuropeptides that control appetite).

237 Neuropeptides that exert cyclic adenosine monophosphate

238 Precursors of neuropeptides that have thus far only been identified in

239 egulation of ASICs, especially by endogenous neuropeptides that potently modulate ASICs.

240 An imbalance between neuropeptides that promote stress and resilience, such a

241 entrating hormone (MCH), orexin, or galanin; neuropeptides that regulate both food-induced and cocain

242 lored seasonal differences in the orexigenic neuropeptides that regulate food intake in wild animals.

243 RF-amide related peptide 3 (RFRP-3) is a neuropeptide thought to inhibit central regulation of fe

244 rovided evidence for a major contribution of neuropeptides to neural signaling within the central com

245 Scg2, a gene that encodes multiple distinct neuropeptides, to coordinate these changes in inhibition

246 neurotransmitter phenotype and expression of neuropeptides, transcription factors and synaptic protei

247 iceptin/orphanin FQ (N/OFQ) is an antistress neuropeptide transmitter in the brain that counteracts c

248 The neuropeptide urocortin 2 (UCN2) and its receptor cortico

249 Cells that express the neuropeptide vasoactive intestinal peptide (VIP) mediate

250 t study, we describe a critical role for the neuropeptide vasopressin (VP) in social buffering of syn

251 We previously identified neuropeptide VF (NPVF) and the hypothalamic neurons that

252 ealth and disease.SIGNIFICANCE STATEMENT The neuropeptide VGF and its peptides have been associated w

253 The neuropeptide VGF has been associated with many metabolic

254 focussed on signaling neurotransmitters and neuropeptides which may be a target for future therapies

255 Drosophila amnesiac gene encodes a secreted neuropeptide whose expression is required for specific m

256 of a potentially broader approach to target neuropeptides with immunotherapies, as both pharmacologi

257 proaches to reveal one venom component, five neuropeptides with two different cysteine motifs, and an

258 l stages influences IGL neurons that express neuropeptide Y (NPY) (hereafter, IGL(NPY) neurons), guid

259 Endogenous neuropeptide Y (NPY) and corticotrophin-releasing factor

260 Neuropeptide Y (NPY) and NPY receptors represent a highl

261 Orexin A (OXA) and neuropeptide Y (NPY) are two hypothalamic neuropeptides

262 The hypothalamic neuropeptide Y (NPY) circuitry is a key regulator of fee

263 Endogenous neuropeptide Y (NPY) exerts long-lasting spinal inhibito

264 We found that neuropeptide Y (NPY) expression identifies a class of GA

265 pproach in mice of both sexes, we found that neuropeptide Y (NPY) expression identifies a major class

266 ted by changes in tonic inhibition of SNA by neuropeptide Y (NPY) in the paraventricular nucleus (PVN

267 ted with reduced tonic inhibition of LSNA by neuropeptide Y (NPY) in the PVN.

268 Neuropeptide Y (NPY) is a 36-amino acid peptide circulat

269 EMENT Within the basolateral amygdala (BLA), neuropeptide Y (NPY) is associated with buffering the ne

270 Here we show that Neuropeptide Y (NPY) is uniquely required for the long-l

271 Among them, neuropeptide Y (NPY) is well known to promote aversive m

272 Neuropeptide Y (NPY) produces anxiolytic effects in rode

273 Within the family of neuropeptide Y (NPY) receptors, the Y(4) receptor (Y(4)R

274 Neuropeptide Y (NPY) signaling via limbic NPY1 and 2 rec

275 We found that Neuropeptide Y (NPY) was significantly down-regulated in

276 Over 80% of these neuron also express neuropeptide Y (NPY), and this coexpression is maintaine

277 rotein (Tg2576), Abeta causes dysfunction in neuropeptide Y (NPY)-expressing hypothalamic arcuate neu

278 (Cell 2019;176:687-701) determined that the neuropeptide Y (NPY)-like receptor 7 (NPYLR7) controls m

279 We investigated a role for neuropeptide Y (NPY)-related signaling in long-term beha

280 ls containing parvalbumin, somatostatin, and neuropeptide Y also show unique topographical distributi

281 he receptor binding motifs of members of the neuropeptide Y and glucagon families modulate receptor a

282 Aptamer-modified microelectrodes for Neuropeptide Y measurement by electrochemical impedance

283 activated L-type Ca(2+) currents in arcuate neuropeptide Y neurons.

284 The neuropeptide receptor neuropeptide Y receptor type 1 (Npy1r) amalgamated multi

285 Here, the conformational dynamics of the neuropeptide Y receptor type 2 (Y2R) during activation w

286 ic, hypothalamic-pituitary-adrenal axis, and neuropeptide Y systems.

287 Neuropeptide Y Y(1) receptors (Y(1)R) have been found to

288 Some in the trafficking of G protein-coupled neuropeptide Y Y2 receptor (NPY(2)R) and serotonin 5-hyd

289 calized with cholinergic starburst ACs, NPY (neuropeptide Y)- and EBF1 (early B-cell factor 1)-positi

290 against calbindin, parvalbumin, calretinin, neuropeptide Y, and somatostatin, and the number of inte

291 bilaterian neuropeptide receptors, including neuropeptide Y, gonadotropin inhibitory hormone (GnIH),

292 and inhibited by orexigenic neuromodulators neuropeptide Y, met-enkephalin, dynorphin and the catech

293 h changes in parvalbumin-, somatostatin- and neuropeptide Y-positive interneurons.

294 es and peptides such as leptin, ghrelin, and neuropeptide Y.

295 ial role of central alpha-klotho to modulate neuropeptide Y/agouti-related peptide (NPY/AgRP)-express

296 of tanycytes ex vivo depolarized orexigenic (neuropeptide Y/agouti-related protein; NPY/AgRP) and ano

297 coordinated action of Caenorhabditis elegans neuropeptide Y/neuropeptide F and serotonin that could a

298 , we identified the evolutionary ortholog of neuropeptide Y/neuropeptide F in the nematode Caenorhabd

299 rvated by inhibitory interneurons expressing neuropeptide Y::Cre (NPY(+)) in the dorsal spinal cord.

300 Orthologs of vertebrate neuropeptide-Y (NPY) known as neuropeptide-F (NPF) have