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1 avage of a host protein-derived peptide (pro-neuropeptide Y).
2 OM), vasoactive intestinal peptide (VIP), or neuropeptide Y.
3 es such as stromal cell-derived factor-1 and neuropeptide Y.
4 decarboxylase-67 (GAD67), somatostatin, and neuropeptide Y.
5 ell type-specific distribution of endogenous neuropeptide Y.
6 e pool neurons that already express GABA and neuropeptide Y.
7 amage, and compensatory changes in EAAT3 and neuropeptide Y.
8 estrogen receptor-alpha colocalization with neuropeptide Y.
9 es and peptides such as leptin, ghrelin, and neuropeptide Y.
10 abundant levels of tyrosine hydroxylase and neuropeptide Y.
11 ferent orexigenic molecules: AgRP; GABA; and neuropeptide Y.
12 lar (3V) infusions of the orexigenic peptide neuropeptide Y 3-36 in awake, freely moving rats and det
14 rocessed for immunocytochemistry for SST and neuropeptide Y, a neuropeptide partially coexpressed in
18 ial role of central alpha-klotho to modulate neuropeptide Y/agouti-related peptide (NPY/AgRP)-express
19 icted neuronal subsets (proopiomelanocortin, neuropeptide Y/agouti-related peptide, and steroidogenic
20 ng hormone neurons but has limited effect on neuropeptide Y/agouti-related protein and proopiomelanoc
21 ons of the arcuate nucleus, specifically the neuropeptide Y/agouti-related protein neurons and the do
22 of tanycytes ex vivo depolarized orexigenic (neuropeptide Y/agouti-related protein; NPY/AgRP) and ano
23 ances the activity of agouti-related protein/neuropeptide Y (AgRP/NPY)-expressing neurons but induces
24 ls containing parvalbumin, somatostatin, and neuropeptide Y also show unique topographical distributi
25 approaches we show this plasticity requires neuropeptide Y, an adrenal cotransmitter and the activat
26 f sympathetic nerves and tissue abundance of neuropeptide-Y, an indicator of sympathetic nerve activi
27 (-/-) mice, and other transcripts, including neuropeptide Y and activating transcription factor-3, ar
29 d by arcuate nucleus neurons that co-express neuropeptide Y and agouti-related protein (NPY/AgRP neur
30 d food intake, body weight, and hypothalamic neuropeptide Y and Agouti-related protein mRNA expressio
31 nduced hepatic FGF21, which caused increased neuropeptide Y and agouti-related protein mRNAs in the h
32 he regulation of social behavior (especially neuropeptide Y and corticotropin-releasing factor) are m
33 disorder are enhanced hippocampal levels of neuropeptide Y and EAAT3 and increased calpain proteolys
34 at co-express agouti-related protein (AgRP), neuropeptide Y and gamma-aminobutyric acid (GABA) are kn
35 he receptor binding motifs of members of the neuropeptide Y and glucagon families modulate receptor a
36 control animals and had lower expression of neuropeptide Y and higher expression of proopiomelanocor
38 f brainstem and hypothalamic neurons express neuropeptide Y and proopiomelanocortin in the arcuate nu
39 of GABAergic GAD67+ interneurons expressing neuropeptide Y and somatostatin are reduced in the hippo
40 2.2 is not required for the specification of neuropeptide Y and vasoactive intestinal polypeptide, in
41 coneogenic enzymes and elevated hypothalamic neuropeptide-Y and agouti-related protein mRNA levels.
42 calized with cholinergic starburst ACs, NPY (neuropeptide Y)- and EBF1 (early B-cell factor 1)-positi
43 n analogue of the C-terminal pentapeptide of neuropeptide Y, and a neuropeptide FF analogue) were sub
44 othalamic neuropeptides proopiomelanocortin, neuropeptide Y, and agouti-related peptide in T1D mice.
45 Ivy cells express nitric oxide synthase, neuropeptide Y, and high levels of GABA(A) receptor alph
46 against calbindin, parvalbumin, calretinin, neuropeptide Y, and somatostatin, and the number of inte
47 -regulating proteins agouti-related peptide, neuropeptide Y, and uncoupling protein 2 in the hypothal
48 hich express the orexigenic neuronal marker, Neuropeptide-Y, and respond to fasting and leptin-induce
50 ress characteristic combinations of GABA and neuropeptide Y as cotransmitters and Lim1,2 and Nurr1 tr
51 the insulin promotor (Ins2) were stained for neuropeptide Y before, during, and after virally induced
52 s that synthesize agouti-related peptide and neuropeptide Y but inhibited anorexigenic neurons that s
53 e BBB-impermeable neuropeptides dalargin and neuropeptide Y chemically conjugated with FC5-Fc fusion
54 .93]) after stressful training; lower plasma neuropeptide Y concentration after stressful training (d
55 ures were heart rate, breathing rate, plasma neuropeptide Y concentration, score on the Response to S
57 rvated by inhibitory interneurons expressing neuropeptide Y::Cre (NPY(+)) in the dorsal spinal cord.
58 eurons that are defined by the expression of neuropeptide Y::Cre (NPY::Cre) act to gate mechanical it
60 cholecystokinin, but inhibited by orexigenic neuropeptide Y, dynorphin and met-enkephalin, consistent
61 the mammalian target of rapamycin pathway in neuropeptide-Y-ergic neurons of the arcuate nucleus, and
62 A significant reduction of calbindin-, NPY (neuropeptide Y)-expressing, and cholinergic interneurons
64 endrites, whereas nitric oxide synthase- and neuropeptide Y-expressing ivy cells provided synaptic an
67 nders to two model peptides, angiotensin and neuropeptide Y, following screening by solution phage pa
68 g mice showed increased levels of C-terminal neuropeptide Y fragments and increased neurogenesis.
69 single nucleotide polymorphism (SNP) in the neuropeptide Y gene has been associated with elevated se
70 bilaterian neuropeptide receptors, including neuropeptide Y, gonadotropin inhibitory hormone (GnIH),
72 essing Drosophila neuropeptide F (dNPF), the neuropeptide Y homolog, strongly correlates with food-od
74 used immunohistochemistry for calretinin and neuropeptide Y in 24 age- and gender-matched patients wi
75 nthesize gamma-amino-butyric acid (GABA) and neuropeptide Y in adult mice leads to starvation within
77 ons expressing parvalbumin, somatostatin and neuropeptide Y in the dentate gyrus, reduced aberrant ne
85 P, corticotropin releasing factor (CRF), and neuropeptide Y levels in adult male Long-Evans rats defe
86 n and attraction is thought to depend on the neuropeptide Y-like receptor NPR-1, because solitary and
88 -expressing interneurons and initiation of a neuropeptide-y-like signaling axis that promotes elevate
89 cystokinin/CB(1) cannabinoid receptor(+) and neuropeptide Y(+) local-circuit interneurons upon SAVA m
90 f both Lifeact-GFP and the SG marker protein neuropeptide Y-mCherry reveals that SGs actively translo
92 and inhibited by orexigenic neuromodulators neuropeptide Y, met-enkephalin, dynorphin and the catech
93 tissue weight, fecal output, arcuate nucleus neuropeptide Y mRNA expression, plasma corticosterone, a
94 ng hormone but surprisingly has no effect on neuropeptide Y mRNA, a neuropeptide previously shown to
96 s, stimulation of the agouti-related protein/neuropeptide Y neurons, and activation of the hypothalam
98 lly significant difference in the density of neuropeptide Y+ neurons between subjects with autism and
99 coordinated action of Caenorhabditis elegans neuropeptide Y/neuropeptide F and serotonin that could a
100 , we identified the evolutionary ortholog of neuropeptide Y/neuropeptide F in the nematode Caenorhabd
101 n, corticotropin releasing hormone, galanin, neuropeptide Y, neurotensin, preproenkephalin and tachyk
102 in, dynorphin) and brain antistress systems (neuropeptide Y, nociceptin [orphanin FQ]) in drug depend
103 r, metabotropic glutamate receptors-2 mGlu2, neuropeptide-Y NPY, and mineralocorticoid receptors MR).
104 l stages influences IGL neurons that express neuropeptide Y (NPY) (hereafter, IGL(NPY) neurons), guid
106 e truncated cleaved form of neurotransmitter neuropeptide Y (NPY) actively promotes a breach of BM va
109 In lean mice, the adipokine leptin inhibits neuropeptide Y (NPY) and agouti-related peptide (AgRP) n
110 bits neurotransmission in neurons expressing neuropeptide Y (NPY) and agouti-related peptide (AgRP) v
113 s that regulate stress and reward, including neuropeptide Y (NPY) and corticotropin-releasing factor
114 s, including somatostatin (SST), tachykinin, neuropeptide Y (NPY) and cortistatin, in a pattern remin
115 was developed for the sensitive detection of neuropeptide Y (NPY) and employed in the analysis of NPY
116 c), containing pro-opoiomelanocortin (POMC), neuropeptide Y (NPY) and growth hormone releasing hormon
118 up-regulating specific target genes, such as neuropeptide Y (NPY) and its Y1 and Y5 receptors (Y5Rs).
120 rgetic state, circulating steroids, and both neuropeptide Y (NPY) and orexin (OX) immunoreactivity.
121 and modulation of neurological signals, with Neuropeptide Y (NPY) and Orexin A (OXA) offering diagnos
123 the lateral hypothalamus (LH) together with neuropeptide Y (NPY) and proopiomelanocortin (POMC) neur
124 the total number of interneurons expressing neuropeptide Y (NPY) and vasoactive intestinal polypepti
127 sh, and here we report the identification of neuropeptide Y (NPY) as both necessary for normal daytim
128 in a structural model of the peptide hormone neuropeptide Y (NPY) bound to its human G-protein-couple
129 in the basolateral amygdaloid complex (BLA), neuropeptide Y (NPY) buffers against protracted anxiety
130 e ontogeny of proopiomelanocortin (POMC) and neuropeptide Y (NPY) cell populations, which exert oppos
133 strongly implicated hindbrain catecholamine/neuropeptide Y (NPY) coexpressing neurons as key mediato
134 ression of agouti-related protein (Agrp) and neuropeptide Y (Npy) coincide with the cyclic changes in
135 c (tg) mice affected primarily the levels of neuropeptide Y (NPY) compared with other neuropeptides.
136 subpopulation of CA1 interneurons expressing neuropeptide Y (NPY) contributes prominently to this dyn
138 we show that the claims of Zhou et al. that neuropeptide Y (NPY) diplotype-predicted expression is c
141 s glucocorticoids have pronounced effects on neuropeptide Y (NPY) expression and as NPY neurons proje
143 pproach in mice of both sexes, we found that neuropeptide Y (NPY) expression identifies a major class
144 gered molecular plasticity including ectopic neuropeptide Y (NPY) expression in granule cells, but wi
145 element binding) binding protein (CBP), and neuropeptide Y (NPY) expression in the amygdaloid brain
148 nes and their cognate receptors belonging to neuropeptide Y (NPY) family mediate diverse biological f
149 ucagon-like peptide-1 (GLP-1), glucagon, and neuropeptide Y (NPY) from circumvallate papillae of Tas1
151 anxiety and other psychiatric disorders and neuropeptide Y (NPY) has emerged as a key component of a
157 ted by changes in tonic inhibition of SNA by neuropeptide Y (NPY) in the paraventricular nucleus (PVN
161 ic inputs to the two populations of striatal neuropeptide Y (NPY) interneurons, plateau low threshold
170 EMENT Within the basolateral amygdala (BLA), neuropeptide Y (NPY) is associated with buffering the ne
175 cord following inflammation or nerve injury, neuropeptide Y (NPY) is poised to regulate the transmiss
176 ported that the sympathetic neurotransmitter neuropeptide Y (NPY) is potently angiogenic, primarily t
179 evious observations that fluorescent-labeled neuropeptide Y (NPY) is usually released within 200 ms a
183 understand whether genetic variation at the Neuropeptide Y (NPY) locus governs secretion and stress
185 cordings were made from GFP (Renilla)-tagged neuropeptide Y (NPY) neurons from the arcuate nucleus of
187 nhibitory effect of Dyn-A on arcuate nucleus neuropeptide Y (NPY) neurons mediated by both 1 and (kap
188 In contrast, kisspeptin inhibits orexigenic neuropeptide Y (NPY) neurons through an indirect mechani
190 he purpose of this study was to characterize neuropeptide Y (NPY) overflow and metabolism from isolat
193 nt protein is expressed under control of the neuropeptide Y (NPY) promoter and striatal NPY-expressin
196 he autonomic nervous system and hypothalamic neuropeptide Y (NPY) release during fasting regulates he
205 d the role of alpha-adrenergic receptor- and neuropeptide Y (NPY) Y1 receptor-mediated vasoconstricti
207 ations of GABAergic interneurones expressing neuropeptide Y (NPY)(+), parvalbumin (PV)(+) and tyrosin
208 neurons [gamma-aminobutyric acid (GABA)(+), neuropeptide Y (NPY)(+), proopiomelanocortin (POMC)(+),
211 study, we identified increased expression of neuropeptide Y (NPY), a pleiotropic growth factor which
212 have studied the subcellular distribution of neuropeptide Y (NPY), a prototypical and broadly express
215 In birds, CART inhibits food intake, whereas neuropeptide Y (NPY), a well-known orexigenic peptide, s
216 ry indicate that cortical astrocytes contain neuropeptide Y (NPY), a widespread neuronal transmitter.
217 from chemotherapy-induced cell death, while neuropeptide Y (NPY), acting via its Y2 receptor (Y2R),
218 c neuron markers proopiomelanocortin (POMC), neuropeptide Y (NPY), agouti-related peptide (AGRP), som
219 ment, hypothalamic mRNA expression levels of neuropeptide Y (NPY), agouti-related protein (AGRP), pro
222 creased mRNA levels of hypothalamic GHS-R1a, neuropeptide Y (NPY), and agouti-related protein (AgRP),
223 (CB), parvalbumin (PV), calretinin (CR) and neuropeptide Y (NPY), and somatostatin (SOM) and glial f
225 augments the SCN clock-resetting effects of neuropeptide Y (NPY), another neurochemical correlate of
226 ctor 3 (ATF3), the neuropeptides galanin and neuropeptide Y (NPY), brain-derived neurotrophic factor
227 -melanocyte-stimulating hormone (alpha-MSH), neuropeptide Y (NPY), glutamate, and GABA from first-ord
228 ), galanin, gastrin-releasing peptide (GRP), neuropeptide Y (NPY), nitric oxide synthase (NOS), serot
229 ed by either gamma-aminobutyric acid (GABA), neuropeptide Y (NPY), or beta-endorphin receptor blockad
230 vels of genes that regulate appetite, namely neuropeptide Y (NPY), pro-opiomelanocortin (POMC) and th
231 he well-characterized neuropeptides, such as neuropeptide Y (NPY), proopiomelanocortin (POMC), orexin
232 ent with PEDF + DHA induced transcription of neuropeptide y (npy), small proline-rich protein 1a (spr
233 xp4 expression induces ectopic expression of neuropeptide Y (Npy), which has been reported to be pres
234 effects were due to disrupted signalling of neuropeptide Y (NPY), which is known to mediate non-phot
235 ar interneurons of the dentate gyrus express neuropeptide Y (NPY), which modulates granule cell activ
237 l transduction pathway modulating release of neuropeptide Y (NPY), which stimulates OE stem cell acti
238 cell activation and promotes the activity of neuropeptide Y (NPY)- and agouti-related peptide (AgRP)-
239 nterneurons express col19a1 mRNA; subsets of neuropeptide Y (NPY)-, somatostatin (Som)-, and calbindi
240 rotein (Tg2576), Abeta causes dysfunction in neuropeptide Y (NPY)-expressing hypothalamic arcuate neu
241 e investigated the properties of neostriatal neuropeptide Y (NPY)-expressing interneurons in transgen
243 (Cell 2019;176:687-701) determined that the neuropeptide Y (NPY)-like receptor 7 (NPYLR7) controls m
244 on, appeared to be precipitated by a loss of neuropeptide Y (NPY)-mediated local circuit inhibition a
245 ood attraction to aversion is regulated by a neuropeptide Y (NPY)-related brain signaling peptide.
256 asting discharge rates of fluorescent-tagged neuropeptide-Y (NPY) (within 200 ms) and tissue plasmino
257 that express pro-opiomelanocortin (POMC) or neuropeptide-Y (NPY) and agouti-related protein (AgRP).
259 ridization to localize appetite-stimulating (neuropeptide Y, NPY; agouti-related protein, AGRP) and a
260 cal activity: the N-terminal region of human neuropeptide Y (NPY1-9, Tyr(1)-Pro(2)-Ser(3)-Lys(4)-Pro(
261 tostatin, vasoactive intestinal polypeptide, neuropeptide Y, or cholecystokinin (antigens commonly co
266 e submucosal plexus, DOReGFP was detected in neuropeptide Y-positive secretomotor and vasodilator neu
268 pressing green fluorescent protein under the neuropeptide Y promoter, we find that, across all layers
269 tance P, calcitonin gene-related peptide, or neuropeptide Y protein expression in DRGs and spinal cor
272 -related behavior, while pretreatment with a neuropeptide Y receptor 5 antagonist prevented the anxio
274 boratory-derived, mutation controlled by the neuropeptide Y receptor homolog npr-1 can affect dauer l
276 multiple signaling molecules, including the neuropeptide Y receptor NPR-1 and the calcineurin subuni
278 Here, the conformational dynamics of the neuropeptide Y receptor type 2 (Y2R) during activation w
280 ion, although this was blocked by a specific neuropeptide Y receptor Y1 receptor antagonist, suggesti
282 coupled receptor (GPCR) related to mammalian neuropeptide Y receptors, functions to suppress innate i
284 Y1 receptor (Y1R) and Y5 receptor (Y5R) for neuropeptide Y share similar actions in the regulation o
285 ive deficits, as well as endocannabinoid and neuropeptide Y system alterations and altered circadian
289 receptor systems (bombesin, neurotensin, and neuropeptide-Y) that offer high potential in the field o
290 d tumor necrosis factor, whereas addition of neuropeptide Y to wild-type macrophages attenuates the r
291 s-associated increase of immunoreactivity of neuropeptide Y, tyrosine hydroxylase, and somatostatin.
293 hypothalamic expression of the orexic gene, neuropeptide Y, was lower and expression of the anorexic
294 (AgRP) neurons (which also release AgRP and neuropeptide Y), we generated mice with an AgRP neuron-s
295 ropeptide F (sNPF), an ortholog of mammalian neuropeptide Y, which we show here is a direct target of
298 Some in the trafficking of G protein-coupled neuropeptide Y Y2 receptor (NPY(2)R) and serotonin 5-hyd