ライフサイエンスコーパス: neuroprotective

1 at is observed in TLE and may be potentially neuroprotective.

2 suggesting that modulating glycolysis may be neuroprotective.

3 ble disease-associated niche, where they are neuroprotective.

4 an increase in mitophagy that is ultimately neuroprotective.

5 ctor (CDNF) is expressed in the brain and is neuroprotective.

6 ransport is disrupted and its restoration is neuroprotective.

7 roke that GPR35 activation by pamoic acid is neuroprotective.

8 ide genetic evidence that Drp1 inhibition is neuroprotective.

9 d neuronal death, whereas ISR activation was neuroprotective.

10 T1-PGC-1alpha axis, which is relevant to the neuroprotective action of 5-HT.

11 ate the mitochondrial effects of 5-HT in its neuroprotective action.

12 10-1), which displayed anti-inflammatory and neuroprotective actions in rodent models of status epile

13 ipheral or brain FNDC5/irisin attenuates the neuroprotective actions of physical exercise on synaptic

14 the hippocampus, a key signaling mediator of neuroprotective actions.

15 inal cleavage fragment, N1, has demonstrated neuroprotective activities in vitro and in vivo.

16 es of these compounds, including potentially neuroprotective activities.

17 superfamily has angiogenic, neurotrophic and neuroprotective activities.

18 Previously, we characterized a potent neuroprotective activity mediated by retinal astrocyte c

19 Neuroprotective activity of parkin has been linked to it

20 ermine a structure-activity relationship for neuroprotective activity.

21 g of Abeta into dense plaque is an important neuroprotective activity.SIGNIFICANCE STATEMENT Genetic

22 evidence that microglial debris clearance is neuroprotective after brain injury in vivo.

23 e findings suggest that neuron-derived E2 is neuroprotective after ischemic brain injury via a mechan

24 netrant when administered intraperitoneally, neuroprotective against Abeta toxicity and restore dimin

25 t synthesis enables gram-scale access to the neuroprotective agent (+/-)-indanostatin.

26 These findings extend the role of ANG as a neuroprotective agent and underscore its potential utili

27 L-Carnosine has shown great promise as a neuroprotective agent in experimental stroke, but transl

28 In vivo efficacy of 15 makes it a promising neuroprotective agent in oxidative stress-related diseas

29 ocampal neurons, and that treatment with the neuroprotective agent P7C3-A20 eradicates persistent rem

30 nimine oxide (23) was shown as a very potent neuroprotective agent.

31 spheres (MSs) incorporating three recognised neuroprotective agents (dexamethasone (DX), melatonin (M

32 , the topical administration of the selected neuroprotective agents appears useful in preventing the

33 3-Arylcoumarins have already been studied as neuroprotective agents by our group.

34 for the identification and implementation of neuroprotective agents could provide novel therapeutics

35 Currently, no neuroprotective agents have been shown to impact the cli

36 The use of neuroprotective agents in stroke has been a notable fail

37 Furthermore, neuroprotective agents, including fenofibrate and simvas

38 elected four compounds to study as potential neuroprotective agents.

39 ic-induced Parkinsonism and the discovery of neuroprotective agents.

40 nds leading to development of more effective neuroprotective agents.

41 ocal injury antagonist distinguished for its neuroprotective, analgesic, and anti-inflammatory proper

42 tribute a significant portion to the in vivo neuroprotective and anti-aging effects of Rap via an aug

43 ive esters have shown significant promise as neuroprotective and anti-inflammatory agents to treat ch

44 e driven by interleukin 10 (IL-10), a potent neuroprotective and anti-inflammatory cytokine.

45 Here, we tested the neuroprotective and anti-inflammatory effects of cromoly

46 of hiPSC-MGE cells after SE mediated several neuroprotective and antiepileptogenic effects in the hos

47 The results demonstrate that IRL-1620 is neuroprotective and attenuates neural damage following c

48 at the level of phosphorylated eIF2alpha is neuroprotective and avoids the pancreatic toxicity cause

49 stem cell (MSC) therapy has been shown to be neuroprotective and can induce neuroregeneration in stro

50 cetylase (HDAC) inhibitors are known to have neuroprotective and cognition-enhancing properties, but

51 that neuron-derived 17beta-estradiol (E2) is neuroprotective and critical for induction of reactive a

52 s assessed by a set of in vitro antioxidant, neuroprotective and cytotoxic assays.

53 ght profitably be used in clinical trials of neuroprotective and disease-modifying treatments, improv

54 hat isoform-D is also expressed selectively, neuroprotective and downregulated in HD mice and patient

55 eading to simplified derivatives with potent neuroprotective and immunosuppressive activity.

56 active protein 1 (MCP1) has been shown to be neuroprotective and is released by astrocytes.

57 previous reports where miR-23a functioned in neuroprotective and muscle atrophy-antagonizing roles.

58 K3 inhibition, and specifically VP3.15, as a neuroprotective and neuroreparative disease-modifying tr

59 n administration of recombinant netrin-1 are neuroprotective and neurorestorative in mouse and rat mo

60 rofilament levels were decreased, indicating neuroprotective and neurorestorative processes.

61 General anesthetics are both neuroprotective and neurotoxic with unclear mechanisms.

62 ammalian brain can be manipulated to adopt a neuroprotective and pro-regenerative phenotype that can

63 therapeutic potential for PD, offering both neuroprotective and symptomatic improvement.

64 ys downstream of TrkB mediate the desirable (neuroprotective) and undesirable (epileptogenesis) conse

65 rine protease APC, exerts vasculoprotective, neuroprotective, and anti-inflammatory activities in rod

66 antihypertensive, antihypercholesterolemic, neuroprotective, antiobese properties and promote gut he

67 ge and Abeta production, while up-regulating neuroprotective APP-alpha-cleavage.

68 We tested three independent neuroprotective approaches-normobaric hyperoxia, the fre

69 body was able to reverse the diminishment in neuroprotective astrocyte reactivity, and attenuate neur

70 discussed with a focus on the translational neuroprotective benefits including their mechanistic bas

71 B-Shc-Akt signaling and thereby preserve the neuroprotective benefits.SIGNIFICANCE STATEMENT Temporal

72 We describe herein the synthesis and neuroprotective capacity of an array of 31 compounds com

73 d species supported and confirmed its strong neuroprotective capacity.

74 e novel carriers have the ability to deliver neuroprotective cargo effectively to the brain.

75 drive tertiary contact in PrP(C), inducing a neuroprotective cis interaction that structurally links

76 ular signaling pathways mediating retrograde neuroprotective communication.

77 early in Parkinson's disease could reflect a neuroprotective compensatory mechanisms and pro-inflamma

78 d not alter the content of picolinic acid, a neuroprotective compound, in red wine.

79 maximum production rate of kynurenic acid, a neuroprotective compound.

80 acker (MWT), and tested whether 38 candidate neuroprotective compounds could improve the mobility of

81 ation for the development of highly specific neuroprotective compounds for the treatment of neurologi

82 ive astrocytes shed EVs containing a host of neuroprotective compounds, which include fibroblast grow

83 TrkB-Shc-Akt signaling pathway mediates the neuroprotective consequences of TrkB activation followin

84 Neuroprotective disruptions of the E3 ubiquitin ligase h

85 ss whether the topical administration of two neuroprotective drugs (brimonidine and somatostatin) cou

86 nical and clinical research identified three neuroprotective drugs acting on different axonal pathobi

87 herapeutic candidates for the development of neuroprotective drugs against AD.

88 orting evidence, Chinese herbal products and neuroprotective drugs are widely used, and the increased

89 g, and cognition-enhancing protein Klotho is neuroprotective due to its anti-inflammatory, antioxidat

90 tudies showed that endogenous estrogens have neuroprotective effect against oxidative damage.

91 nic activity, is found to have the strongest neuroprotective effect against oxidative neurotoxicity a

92 A major technical hurdle in determining any neuroprotective effect by DBS is its use in mid- to late

93 dose erythropoietin has been shown to have a neuroprotective effect in preclinical models of neonatal

94 onnectivity analyses crucially supported the neuroprotective effect of bilingualism by showing an inc

95 in the whole population, we did not find any neuroprotective effect of brimonidine or somatostatin.

96 er hypoxia-ischaemia; however, the potential neuroprotective effect of facilitated passive cooling is

97 The neuroprotective effect of GPR35 activation depends on pr

98 We then tested the neuroprotective effect of neuregulin-1 (NRG-1) against h

99 Neuroprotective effect of placenta-derived mesenchymal s

100 Here, we assessed the neuroprotective effect of topical eye delivery of the p3

101 HT induction, DMQ-MSs showed a significantly neuroprotective effect on RGCs compared to OHT only cont

102 both PFC and VTA DAergic activity states, a neuroprotective effect that persists into adulthood.

103 Such neuroprotective effect was obtained using the recombinan

104 zes with alphaS, has been shown to provide a neuroprotective effect, but the molecular mechanism by w

105 ith anti-galectin 1 antibody decreased their neuroprotective effect, suggesting that PMSC exosomes li

106 h the prediction that C1q reduction exerts a neuroprotective effect.

107 However, the neuroprotective effector proteins induced by RBM3 and th

108 cid (DHA) has been shown to have significant neuroprotective effects after hemisection and compressio

109 It displayed neuroprotective effects against oxygen-glucose deprivati

110 ivity, demonstrating powerful and functional neuroprotective effects against THC-induced developmenta

111 lypyrrolidone (PVPP) winery residue, and its neuroprotective effects and ability to modulate the kine

112 sults demonstrate that chrysophanol provided neuroprotective effects and inhibited glial activation,

113 We demonstrate that the TBK1-mediated neuroprotective effects are due to phosphorylation-depen

114 eting HIPK2 and its kinase activity can have neuroprotective effects by elevating Parkin protein leve

115 A lack of convulsant activity coupled with neuroprotective effects have led some to postulate an al

116 Prompted by the discovery that NAS neuroprotective effects in EAE are abrogated in mice lac

117 lyn sodium, an FDA approved compound, exerts neuroprotective effects in mouse models of Alzheimer's d

118 t in stroke, with Ang-(1-7) reported to have neuroprotective effects in pre-clinical stroke models.

119 determined that two of these compounds exert neuroprotective effects in the nanomolar concentration r

120 ERM raloxifene has structural and functional neuroprotective effects in the retina.

121 human retinal degeneration due to its potent neuroprotective effects in various animal models.

122 the goal of this work was to better test the neuroprotective effects of a formulation of micronized P

123 rk uncovers molecular networks which mediate neuroprotective effects of Emapunil, including microglia

124 We recently reported that the neuroprotective effects of fingolimod in 5xFAD transgeni

125 rain through carbogen breathing reversed the neuroprotective effects of FLASH, while radiochemical st

126 obiota with antibiotics partly abolishes the neuroprotective effects of IF.

127 rther demonstrating functional and long-term neuroprotective effects of l-theanine in the mesocortico

128 Purpose To investigate the neuroprotective effects of low-intensity pulsed (LIP) ul

129 ecreased cellular survival without affecting neuroprotective effects of melatonin.

130 The neuroprotective effects of micronized PEA (PEA-m) formul

131 ce of multiple molecular contributors to the neuroprotective effects of NAPE-PLD deletion, including

132 Here, we explored the neuroprotective effects of pharmacologically activating

133 press the human Abeta42 peptide to assay the neuroprotective effects of PI3K in adult Drosophila mela

134 onal imaging endpoints, aimed to examine the neuroprotective effects of RIC in ischemic stroke model.

135 t for additional evaluation of the potential neuroprotective effects of senolytics on glaucoma and ot

136 Depletion of microglia abolishes the neuroprotective effects of sTREM2.

137 results suggest that topical rh-NGF exhibits neuroprotective effects on retinal neurons via influenci

138 Their potential neuroprotective effects were examined in mouse focal isc

139 NPs) were designed and synthesized and their neuroprotective effects were measured using in vitro and

140 encapsulating carnosine exhibited remarkable neuroprotective effects with a dose of carnosine 3 order

141 d less inflammatory phenotypes and may exert neuroprotective effects.

142 nsitization) implies that agonists may exert neuroprotective effects.

143 ediated neutralization of pHERV-W ENV exerts neuroprotective effects.

144 79 e4 carriers in order to examine potential neuroprotective effects.

145 -OXA) possesses anti-inflammatory and potent neuroprotective effects.

146 ntibacterial, antifungal, antiparasitic, and neuroprotective effects.

147 ggests that chronic gamma entrainment offers neuroprotective effects.

148 the target calcium channels associated with neuroprotective effects.

149 The neuroprotective efficacy of hydroxyurea (HU) remains unc

150 pment can be modulated extrinsically by both neuroprotective (environmental enrichment) and detriment

151 pment can be modulated extrinsically by both neuroprotective (environmental enrichment) and detriment

152 ly mediates immune surveillance and is often neuroprotective, excessive engagement of the system can

153 ion of Cdk5/p25 hyperactivation in vivo is a neuroprotective factor during ALS pathogenesis by crossi

154 riptional regulatory network mediated by the neuroprotective factor Hif2a as underlying neural circui

155 e adenine dinucleotide (NAD(+)) synthase and neuroprotective factor, significantly mitigates mutant H

156 ly, but also clinically as immunomodulatory, neuroprotective factors for treating trauma or disease i

157 tate, improving synaptic function, enhancing neuroprotective factors, and reducing DNA damage in neur

158 e to sequester the toxic species acting in a neuroprotective fashion.

159 ls (15-30mg/l) were achieved at 2 h and were neuroprotective following HI, but ethanol vehicle was pa

160 f mothers with HIV during pregnancy might be neuroprotective for the child, and when continued post p

161 PMSCs exhibit neuroprotective function by increasing cell number and n

162 ic efficiency is potentially involved in the neuroprotective function of DJ-1 as well as its role in

163 Our study thus identifies a neuroprotective function of microglia in the clearance o

164 ur results provide evidence of the autocrine neuroprotective function of VEGF on RGCs is crucially in

165 eloped an EPO-R76E derivative that maintains neuroprotective function without effects on hematocrit,

166 se in neurites, suggesting that they exhibit neuroprotective function.

167 on by Mdm2 could be targeted to increase its neuroprotective functions, which has implications for an

168 se to inflammation to mediate a compensatory neuroprotective gene expression program that desensitize

169 ral-mediated, genome-wide screen to identify neuroprotective genes in wild-type and Huntington's dise

170 nitric oxide synthetase (NOS1 and NOS3) and neuroprotective genes with downregulation of proinflamma

171 We focused on APOE e2, an established neuroprotective genetic variant against Alzheimer's dise

172 ck after AMI randomized in the Neuroprotect (Neuroprotective Goal Directed Hemodynamic Optimization i

173 We propose a model of neuroprotective homeostatic plasticity, extending organi

174 P1 disinhibition on mTORC1 repression may be neuroprotective; however, whether 4E-BP1 overexpression

175 In vitro studies showed DMQ-MSs to be neuroprotective in a glutamate-induced cytotoxicity mode

176 ody (KB) produced in ketogenic diet (KD), is neuroprotective in aralar-knock-out (KO) neurons and mic

177 n repair and suggest that oral GlcNAc may be neuroprotective in demyelinating diseases like MS.

178 e; however, whether 4E-BP1 overexpression is neuroprotective in mammalian neurons is yet to be fully

179 tudies have shown that intranasal insulin is neuroprotective in models of Alzheimer's disease, Parkin

180 LTCC blockers were neuroprotective in mouse neurotoxin models of PD, and is

181 Inhibition of miR-142-3p could be neuroprotective in MS.

182 Disrupted CX3CR1-CCR2 signaling was neuroprotective in part by attenuating monocyte and neut

183 organ injury in other disease states and are neuroprotective in preclinical models of critical illnes

184 CK (Rho kinase) pathway has been shown to be neuroprotective in SOD1(G93A) mice, the most commonly us

185 ertain strains of T. gondii infection can be neuroprotective in the context of a secondary insult lik

186 r cobalamin, a vitamin B12 vitamer, would be neuroprotective in vitro and in vivo.

187 Decreased Tet2 activity is neuroprotective, in vivo, and may be a new therapeutic t

188 f 5'-AMP-activated protein kinase (AMPK) and neuroprotective induction of autophagy, implicating the

189 ly neurotoxic quinolinic acid instead of the neuroprotective kynurenic acid in mood disorders but not

190 s pathway, thereby demonstrating a potential neuroprotective mechanism involving SORLA.

191 We demonstrated that the neuroprotective mechanism of the investigated PPZ is bas

192 of how cholesterol metabolism can modulate a neuroprotective mechanism that attenuates alpha-synuclei

193 LC-derived norepinephrine (NE) can stimulate neuroprotective mechanisms and modulate immune cells, wh

194 related to neurodegenerative phenotypes and neuroprotective mechanisms of the small-molecule ISRIB d

195 eractions promote viral clearance via mainly neuroprotective mechanisms, they may also promote neurop

196 tome may provide valuable insight into these neuroprotective mechanisms.

197 y in biosynthetic pathways of prohomeostatic/neuroprotective mediators neuroprotectin D1 (NPD1) and e

198 r LPS delivered systemically can also induce neuroprotective microglia in the spinal cord.

199 rmacologic or genetic approaches can yield a neuroprotective microglial phenotype that profoundly aid

200 in, without affecting the release of healthy neuroprotective mitochondria.

201 al disorders, and there is an unmet need for neuroprotective modalities to improve photoreceptor surv

202 Stimulated astrocytes secrete EVs with neuroprotective molecules including heat shock proteins,

203 und that inhibits alphaSyn misfolding and is neuroprotective, multiple compounds that restore phagocy

204 recovery and quality, and the fact that the neuroprotective olfactory ensheathing cell (OEC) subset

205 l phagocytosis after brain injury in vivo is neuroprotective or neurotoxic is not known.

206 discuss the evidence for the neurotoxic and neuroprotective pathways that have been attributed to mi

207 In brain, neuroprotective pathways were identified as potential ta

208 The neuroprotective potential of astrocytes was itself sensi

209 t that CK2 inhibitors could release the full neuroprotective potential of HSJ1, and deserve future in

210 aim of the current study was to evaluate the neuroprotective potential of mesenchymal stem cells (MSC

211 Finally, the neuroprotective potential of optogenetic collicular stim

212 hium, a well-known mood stabilizer, has both neuroprotective, pro-neurogenic as well as antitumor eff

213 r the development of treatments that augment neuroprotective processes while limiting ongoing immunop

214 onded to luminal infection by upregulating a neuroprotective program via beta(2)-adrenergic receptor

215 we go on to demonstrate that hydralazine has neuroprotective properties against endogenous and exogen

216 eristics of an immature neutrophil, that had neuroprotective properties and drove CNS axon regenerati

217 The inhibitors show neuroprotective properties in a murine hippocampal cell

218 global neurocognition, it may have specific neuroprotective properties in attention/vigilance, parti

219 o possess antioxidant, antiinflammatory, and neuroprotective properties in experimental autoimmune en

220 SPO ligands have shown anti-inflammatory and neuroprotective properties in models of CNS injury.

221 DM1 myoblasts, while compounds 1 and 53 have neuroprotective properties in SMA-derived cells.

222 Although recent studies have explained the neuroprotective properties of PEA-OXA, nothing is known

223 d astrocytes promote synaptogenesis, exhibit neuroprotective properties, display calcium transients i

224 imental work shows that heparinoids may have neuroprotective properties.

225 ate in various neural regions and to possess neuroprotective properties.

226 (ID) causing mutations is activity-dependent neuroprotective protein (ADNP), with intact ADNP protect

227 is caused by mutations in activity-dependent neuroprotective protein (ADNP).

228 an active fragment of the activity-dependent neuroprotective protein (ADNP).

229 tein-alpha (sAPPalpha) is a neurotrophic and neuroprotective protein that can promote synaptic plasti

230 njury after alkali burn and explored a novel neuroprotective regimen suitable for prompt administrati

231 rontotemporal dementia mice, both drugs were neuroprotective, rescued memory deficits and reduced hip

232 ogens to achieve a therapeutically effective neuroprotective response against ISCI.

233 herent variability and sex-dependence of the neuroprotective response to HT, with the majority of stu

234 Muller survival pathways might underlie the neuroprotective response.

235 of sporadic ALS and uncovers both an initial neuroprotective role for astrocytes and the cell type-sp

236 Herein, we report a neuroprotective role for microglia in the clearance of n

237 es mitigates inflammation, consistent with a neuroprotective role for Shh signaling after injury.

238 ere, we argue that microglia play an overall neuroprotective role in prion pathogenesis.

239 n striatal and cortical neurons that plays a neuroprotective role in these cells.

240 idered to have a safer profile; however, its neuroprotective role in vivo is not known.The goal of th

241 aper, Gratuze et al. demonstrated a putative neuroprotective role of a key Alzheimer risk variant, TR

242 eration of neural progenitors, arguing for a neuroprotective role of adiponectin.

243 ulting in neuroinflammation, which turns the neuroprotective role of microglia detrimental as charact

244 Altogether, these findings validate neuroprotective role of Shh signaling and highlight the

245 Evidences have suggested a neurotrophic and neuroprotective role of VEGF, albeit in retina, cellular

246 lly, ROS scavenging by antioxidants played a neuroprotective role via increasing HIF-1alpha expressio

247 unction, recent data suggest that they exert neuroprotective roles in CNS homeostasis through continu

248 ndent sensitizing influences such as loss of neuroprotective S1P are more important drivers of neurod

249 s Ly-6C(Lo) monocytes/macrophages to relay a neuroprotective signal into the ischemic brain.

250 dentified a prominent lipid component of the neuroprotective signal through metabolomics screening.

251 s, we identified a novel non-cell autonomous neuroprotective signaling cascade mediated through PI3K

252 hate (S1P) is a potent vasculoprotective and neuroprotective signaling lipid, synthesized primarily b

253 ameter) to assess penetration of a candidate neuroprotective siRNA.

254 TATEMENT Data in this report indicate that a neuroprotective spinal cord microglia response can be tr

255 spiratory support, and potentially employing neuroprotective strategies (eg, targeted temperature man

256 f mutant Htt aggregates remains limited, and neuroprotective strategies combating mutant Htt-induced

257 osis (MS) research, there is still a lack of neuroprotective strategies, because the main focus has r

258 urotoxicity and the development of effective neuroprotective strategies.

259 ations and may enable discovery of selective neuroprotective strategies.

260 euro-axonal injury, is paramount to optimize neuroprotective strategy in MS.

261 at targeting CSF1R signaling may be a viable neuroprotective strategy in PD that disrupts pro-inflamm

262 via PKM2-to-PKM1 substitution is a promising neuroprotective strategy.

263 chemic event, there is resurgent interest in neuroprotective stroke therapies.

264 Given these neuroprotective studies, we hypothesized that a prolonge

265 ormal tau indicates the presence of inherent neuroprotective systems in brain.

266 To identify such a neuroprotective target, we conducted a set of complement

267 receptors have been implicated as potential neuroprotective targets for glaucoma.

268 ical Drp1 inhibition has been put forward as neuroprotective, the specificity and mechanism of the in

269 treatment has the potential to be used as a neuroprotective therapeutic approach in Machado-Joseph d

270 brain cell types, may be able to unlock the neuroprotective therapeutic potential of idebenone or re

271 cological inhibition of PFKFB3 is a suitable neuroprotective therapeutic strategy in excitotoxic-rela

272 Abeta-mediated oxidative stress, supporting neuroprotective therapies aimed at ameliorating defects

273 These data open the possibility of new neuroprotective therapies aimed at SPN synapse function,

274 t challenges in the development of potential neuroprotective therapies has been the lack of reliable

275 Although neuroprotective therapies have been suggested to have th

276 d death worldwide, yet there are no approved neuroprotective therapies that improve neurological outc

277 rogression, there is an unmet need for novel neuroprotective therapies to support RGC survival.

278 fficacy of new treatments; however, previous neuroprotective therapies, based on systemic delivery in

279 t to intervene for the purpose of evaluating neuroprotective therapies.

280 dria will therefore be central to developing neuroprotective therapies.

281 eta2 may represent a target for prophylactic neuroprotective therapy in populations at high risk of s

282 ative states, and potentially intervene with neuroprotective therapy.

283 We next found that astrocytes are neuroprotective to seeded aggregation within motor neuro

284 ggest a previously unknown mechanism for the neuroprotective traits of widely used preventive therape

285 nAChR) in fetal microglia will augment their neuroprotective transcriptome profile, while the antagon

286 describe a clinically translatable topical, neuroprotective treatment (recombinant human nerve growt

287 Together, our results suggest that a neuroprotective treatment based on the enhancement of th

288 rapidly translatable, disease-modifying, and neuroprotective treatment for Friedreich's ataxia.

289 sue to identify a subset of patients in whom neuroprotective treatment might be of benefit.

290 , thus constituting a promising agent for HD neuroprotective treatment.

291 human immunodeficiency virus infection, such neuroprotective treatments could ultimately be considere

292 However, disease-modifying, neuroprotective treatments for glaucoma remain a major u

293 Attempts to develop neuroprotective treatments for neurodegenerative disorde

294 d GP+RAP/alpha-syn, is capable of triggering neuroprotective Treg responses in synucleinopathy models

295 Sample size estimates for definitive neuroprotective trials ranged from 142 to 366 patients p

296 For future neuroprotective trials, it is essential to accurately es

297 , which can be used to stratify patients for neuroprotective trials.

298 et risk reduction strategies, and administer neuroprotective trials.

299 Alzheimer's disease (AD), e4, and the major neuroprotective variant, e2.

300 ll patients and since insulin therapy may be neuroprotective, we sought to explore the association be