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1 r loop, and transmembrane VII regions of the neurotensin receptor.
2 a nonpeptide antagonist of the high-affinity neurotensin receptor (0.25 or 2.5 microgram, i.c.v., or
3  groups were inherently detrimental to human neurotensin receptor 1 (hNTR1) binding affinity or recep
4 peutic efficacy of oAd/DCN/LRP-PEG-NT toward neurotensin receptor 1 (NTR)-overexpressing pancreatic c
5 cally induced hypothermia (PIH) by the novel neurotensin receptor 1 (NTR1) agonist ABS-201 in a focal
6 mbinations that preferentially interact with neurotensin receptor 1 (NTR1) and our stabilized mutants
7 2-carboxylic acid (SR48692), a high-affinity neurotensin receptor 1 (NTR1) antagonist.
8                                        Using neurotensin receptor 1 (NTR1) as a proof of principle, w
9   In this study, we define the high-affinity neurotensin receptor 1 (NTR1) as a tractable new molecul
10                      Increased expression of neurotensin receptor 1 (NTR1) has been shown in a large
11                         Neurotensin (NT) and neurotensin receptor 1 (NTR1) have been shown to play a
12                                              Neurotensin receptor 1 (NTR1) is a G protein coupled rec
13                                              Neurotensin receptor 1 (NTR1) is overexpressed in ductal
14 tivating the G protein-coupled receptor, the neurotensin receptor 1 (NTR1).
15                                          The neurotensin receptor 1 (NTS(1)) is a G protein-coupled r
16                                              Neurotensin receptor 1 (NTS(1)) is involved in the devel
17                      Labeled ligands for the neurotensin receptor 1 (NTS(1)R), which is expressed in
18                               Small molecule neurotensin receptor 1 (NTSR1) agonists have been pursue
19 gnaling leading to NED through activation of neurotensin receptor 1 (NTSR1) and neurotensin receptor
20                                              Neurotensin receptor 1 (NTSR1) and related G protein-cou
21 quired for this network disturbance, we used neurotensin receptor 1 (Ntsr1) cre-driver mice to ablate
22 on microscopy structure of full-length human neurotensin receptor 1 (NTSR1) in complex with truncated
23                                              Neurotensin receptor 1 (NTSR1) is a G-protein-coupled re
24                                              Neurotensin receptor 1 (NTSR1) is overexpressed in most
25 STR1, SSTR2), kisspeptin recepotor (KissR1), neurotensin receptor 1 (NTSR1), neuropeptide S receptor
26    Here, using the prototypical class A GPCR neurotensin receptor 1 (NTSR1), we show that small molec
27       We previously reported that SBI-553, a neurotensin receptor 1 (NTSR1)-positive allosteric modul
28 SBI-810, a beta-arrestin-biased modulator of neurotensin receptor 1 (NTSR1).
29 urons that is dependent on the expression of neurotensin receptor 1 (Ntsr1).
30 ese effects requires mast cell expression of neurotensin receptor 1 and neurolysin.
31  of synthetic DNA libraries, we first evolve neurotensin receptor 1 for high stability and expression
32                        Starting from the rat neurotensin receptor 1, a class A GPCR, we generated a s
33  receptors (angiotensin II type 1A receptor, neurotensin receptor 1, vasopressin V2 receptor, thyrotr
34                    Compound 1 binds to human neurotensin receptors 1 and 2 with IC(50) of 10.6 and 54
35  of the GHS-R is most closely related to the neurotensin receptor-1 (NT-R1) (35% overall protein iden
36                                              Neurotensin receptor-1 (NTR1) is a promising target for
37 on by binding of its high affinity receptor, neurotensin receptor-1 (NTR1).
38 nkers or chelators, in tracers targeting the neurotensin receptor-1 (NTSR-1).
39 Peptide-based radiopharmaceuticals targeting neurotensin-receptor-1 (NTS(1)) are mainly stabilized us
40  and neurotensin receptor 3 (NTSR3), but not neurotensin receptor 2 (NTSR2).
41              Pharmacological manipulation of neurotensin receptor 2 confirms behavioural effects obse
42 acrophage inflammatory protein 1 (MIP-1) and neurotensin receptor 2.
43 vation of neurotensin receptor 1 (NTSR1) and neurotensin receptor 3 (NTSR3), but not neurotensin rece
44 te as to whether a peripherally administered neurotensin receptor agonist represents a sound strategy
45 ta further support a role for NT69L or other neurotensin receptor agonists to treat nicotine addictio
46 tained high affinity and agonist potency for neurotensin receptors and exhibited dramatically improve
47 ural elements for species specificity of the neurotensin receptors, and may expedite developing nonpe
48 ither the protein phosphatase calcineurin or neurotensin receptors, and persists surprisingly long af
49 otensin analogs, biological functions of the neurotensin receptors, and structural elements for speci
50 eadministration of a mu opioid receptor or a neurotensin receptor antagonist into the ventral PAG.
51                Pretreatment of rats with the neurotensin receptor antagonist SR-48, 692 inhibits toxi
52 r to be the high-affinity receptor since the neurotensin receptor antagonist SR48692, when given i.c.
53 wo new tritiated tracers for angiotensin and neurotensin receptors are described.
54  administered peripherally, serum levels and neurotensin receptor binding potency of 1 peaked within
55 more, neurotensin knockout in the NAcLat and neurotensin receptor blockade in the VTA each abolished
56 e a basis for rationalizing mutations of the neurotensin receptor gene but also offer insights into u
57 e constructed a series of chimeric rat/human neurotensin receptor genes and expressed them by transie
58                                              Neurotensin receptors have been implicated in a wide var
59                                High-affinity neurotensin receptors in the periphery appear to play a
60                Ca2+ mobilization mediated by neurotensin receptors is also inhibited by ET-18-OCH3.
61                                          The neurotensin receptor ligand (111)In/(177)Lu-3B-227 has d
62  Slosky et al. report a beta-arrestin-biased neurotensin receptor ligand that may curtail drug abuse
63  types, we synthesized tritiated fluorescent neurotensin receptor ligands ([(3)H]13, [(3)H]18) and th
64 he C-terminal region of NT1-13 recognized by neurotensin receptors, modulate distension-induced relea
65 roscopic immunolabeling of the high-affinity neurotensin receptor (NTR) and neurotensin in these subd
66  the present study, we have cloned the human neurotensin receptor (NTR) gene, determined its structur
67                            The prevalence of neurotensin receptor (NTR) in several human tumors makes
68          To date, there are two types of the neurotensin receptor (NTR) that have been molecularly cl
69 1AR), endothelin type A receptor (ETAR), and neurotensin receptor (NTR).
70 e promoter region of the mouse high affinity neurotensin receptor (Ntr-1) gene was characterized, and
71          Accumulating evidence suggests that neurotensin receptors (NTRs) play key roles in cancer gr
72 l and hydrodynamic experiments that purified neurotensin receptor NTS1, a class A GPCR, dimerizes in
73                                   The type 1 neurotensin receptor (NTS1) belongs to the G protein-cou
74                          Compounds active at neurotensin receptors (NTS1 and NTS2) exert analgesic ef
75    We previously determined the structure of neurotensin receptor NTSR1 in an active-like conformatio
76  and a hormone through the activation of the neurotensin receptor NTSR1, a G-protein-coupled receptor
77 re of a constitutively active, agonist-bound neurotensin receptor (NTSR1) and molecular dynamics simu
78 opeptide growth factor, and its two specific neurotensin receptors, NTSR1 and NTSR2, were shown to be
79  clinical trials for the targeted therapy of neurotensin receptor-positive cancers.
80 nigra, but not the VTA, and was dependent on neurotensin receptor signaling, postsynaptic calcium, an
81  (AS-MOR MM), antisense PNAs targeted to the neurotensin receptor subtype 1 (AS-NTR1), or saline and
82 ur results led us to propose a region of the neurotensin receptor that may be involved in determining
83 ding only to microspots corresponding to the neurotensin receptor; this specificity was further demon
84 pitates with G(alpha)q/11 upon activation of neurotensin receptors; this association is inhibited by
85 c pocket on the extracellular surface of the neurotensin receptor to accommodate its ligands apparent
86 in-G were found to be potent agonists of rat neurotensin receptor type 1.
87                     Compounds acting via the neurotensin receptor type 2 (NTS2) are known to be activ
88 cosylated Thr10 contulakin-G for a number of neurotensin receptor types including the human neurotens
89                                              Neurotensin receptor was expressed in 88% of the surgica
90  the observed Kd values at the rat and human neurotensin receptors were 0.046 and 5.8 nM, respectivel