ライフサイエンスコーパス: newly

1 We sought to describe the prevalence of newly acquired frailty, its clinical course, and the co-

2 Newly acquired memory traces are spontaneously reactivat

3 U survivors; 2) one-year survivors reporting newly-acquired chronic pain; and (3) one-year survivors

4 tes that there are still patients at risk of newly acquiring drug resistance despite having access to

5 e participants were adults (aged >=18 years) newly admitted to TFH facilities with active psychotic s

6 While newly advanced multiplexed FISH imaging offers possibili

7 n of co-expression domains with expanded and newly-appearing (emerged) DCEs.

8 (AZI) targeting yaws and trachoma, with the newly approved ivermectin, albendazole, diethylcarbamazi

9 ical examination is an opportunity to ensure newly arrived refugees and other eligible populations re

10 for the US Domestic Medical Examination for Newly Arriving Refugees, including an evaluation for mal

11 acific, morphological information, and three newly assembled draft genomes to compare contemporary pa

12 he efficient axonal sorting and transport of newly assembled PRV virions.

13 fection by vesicular stomatitis virus (VSV), newly assembled VSV particles are released from the surf

14 itivity (dprime) for stimuli associated with newly-assigned ingroups.

15 en occurs by fusion of actin fibers from the newly attached cells into the actin cable and defusion f

16 We make use of newly available data that include roughly 5 million link

17 glycans in multicellular interactions using newly available datasets and tools, including glycan bio

18 e-shifting prey to successfully establish in newly available habitat following climate warming.

19 n laboratory (cath lab) activation time is a newly available process measure for patients with ST-seg

20 egans based on a snapshot of CDK activity in newly born cells.

21 ases, including Rsp5, the Dsc complex, and a newly characterized E3 ligase, Pib1.

22 Each of these newly characterized inter-map relationships strongly dev

23 cidence was 0.40/100 py (20/4992.8 py) among newly circumcised men and 0.98/100 py (118/12095.1 py) a

24 Among those newly classified as having IDH, an estimated 0.6% (95% C

25 Newly collected untreated human glioblastoma data in Sea

26 cking and molecular dynamics simulation with newly constructed mA(3)AR and hA(3)AR homology models.

27 RL on endocytic traffic and cell division in newly created human PT CRISPR/Cas9 OCRL knockout cells,

28 ia multiple distinct interfaces, including a newly defined charge-based interaction.

29 The risk models for the newly defined five geriatric outcomes that we created ca

30 Using our newly defined metric, we identify multiple mis-assembled

31 A newly derived model incorporating the PERSEVERE biomarke

32 These newly derived oligonucleotides named malaswitches bind t

33 he initial rate of payload release from this newly derived scaffold to be directly proportional to th

34 nor NA group deriving from NAAD, produced by newly described endolysosomal activities of NA phosphori

35 itionally, we find that in aged animals this newly described QR2 pathway is chronically under activat

36 In this paper, a newly designed composite acoustic lens that can achieve

37 in adult pigs or non-human primates using a newly designed device produces homogeneous delivery thro

38 small voltage potential oscillation across a newly designed electro-chemical catalytic membrane signi

39 nvolves the integration of ion channels with newly designed gating properties into cardiomyocytes.

40 Herein, we report two newly designed two-dimensional COFs based on a (diarylam

41 toma, here we evaluated the potential of the newly developed 1-(2-[(18)F]fluoroethyl)-L-tryptophan (1

42 ivity on the pathogenesis of AD using GiD, a newly developed animal model of reactive astrocytes, whe

43 We critically review in depth newly developed biosensing methods especially for in-fie

44 Newly developed BLIs offer some advantage over older BLI

45 Herein, we report a newly developed combinatorial library of cholesteryl-bas

46 ants (EOCs), the term used not only to cover newly developed compounds but also compounds newly disco

47 Spurred by newly developed drug delivery systems (DDSs), side effec

48 A newly developed ELISA showed that domain-specific PLA(2)

49 s well suited to evaluate the performance of newly developed force fields.

50 Here, using newly developed human cell-free systems that recapitulat

51 ary and those identified in urine, using the newly developed hybrid search method.

52 Utilizing a standardized dataset based on a newly developed list of 27 univocally defined complicati

53 A newly developed luciferase-based DENV-2 protease reporte

54 tantly, we demonstrate the advantages of our newly developed method for the protection and deprotecti

55 hput bottom-up proteomic method enabled by a newly developed MS-compatible photocleavable surfactant,

56 Here, we introduce the SurgeON(TM) system: a newly developed non-invasive modular tool which transmit

57 Here, using a panel of newly developed peptide-exchangeable peptide/HLA multime

58 changed diagnosis from PIC to MFC because of newly developed peripheral lesions.

59 Newly developed photonic materials permit subambient coo

60 t of gut microbiota and its metabolism, this newly developed platform will be of great potential in b

61 f eligible instruments was evaluated using a newly developed psychometric quality assessment tool.

62 tive C-H functionalization reactions using a newly developed Rh(2) (S-2-Cl-5-CF(3) TPCP)(4) catalyst.

63 By applying newly developed statistical methods for ancestral recomb

64 At cross-validation, the newly developed SYNTAX score II, termed SYNTAX score II

65 Using newly developed tools to reconstruct CMV haplotypes, we

66 afety, tolerability, and immunogenicity of a newly developed, tetravalent Ad26 vaccine with the previ

67 National rates of newly diagnosed acute and chronic HBV infections decline

68 ntified in approximately 3% of children with newly diagnosed acute lymphocytic leukaemia, and studies

69 e safety profile and showed high activity in newly diagnosed AML and molecularly defined subsets of r

70 R(low) monocytic MDSCs has been described in newly diagnosed AML patients, and deciphering the underl

71 nd transfusion independence in patients with newly diagnosed AML.

72 -derived primary multiple myeloma cells from newly diagnosed and relapsed/refractory patients, includ

73 For newly diagnosed breast cancer, estrogen receptor status

74 elated anemia is present in more than 60% of newly diagnosed cancer patients and is associated with s

75 Probands with newly diagnosed cancer-associated pathogenic variants we

76 ts (SEs), adverse events (AEs), serious AEs, newly diagnosed chronic medical conditions, and immediat

77 Compared to those with newly diagnosed DM, TB patients with diagnosed DM had hi

78 nt for dyslipidemia, and group 2, those with newly diagnosed dyslipidemia who were under lifestyle in

79 A total of 3349 newly diagnosed HCC patients were enrolled and retrospec

80 have concurrent gallstone cholangitis and a newly diagnosed hepatocellular carcinoma.

81 predicting survival outcome in patients with newly diagnosed HER2-positive breast cancer.

82 testing data revealed an increasing trend in newly diagnosed HIV among PWID but not linkage to HIV me

83 The percentage of newly diagnosed HIV increased from .7% in 2012 to .8% in

84 PET/CT in the same patients presenting with newly diagnosed intermediate- or high-risk PCa.

85 , life expectancy of more than 12 weeks, and newly diagnosed International Federation of Gynecology a

86 CT (ceCT) or BS plus ceCT, for patients with newly diagnosed MBC.

87 A newly diagnosed mental disorder was associated with youn

88 significance of dysplastic hematopoiesis in newly diagnosed MM, which can be screened with moderate

89 examethasone (KRd) regimen for patients with newly diagnosed multiple myeloma (NDMM).

90 f 3-drug induction regimens in patients with newly diagnosed multiple myeloma to result in a substant

91 37 transplant-ineligible (TIE) patients with newly diagnosed multiple myeloma were randomly assigned

92 xel-containing regimens in the management of newly diagnosed ovarian cancer.

93 young adults (age range, 6 to 21 years) with newly diagnosed overt type 1 diabetes to receive subcuta

94 ts that this combination should be tested in newly diagnosed paediatric patients with high-risk acute

95 lymphoblastic leukemia (ALL) cells from 388 newly diagnosed patients after in vivo high-dose methotr

96 ns for decompensated ALD, and an increase in newly diagnosed patients with AUD/ALD post-COVID-19 pand

97 ion and its therapeutic response, notably in newly diagnosed patients with BD.

98 Insurance Research Database for all 112,929 newly diagnosed patients with POAG from January 2010 thr

99 fy a genomically defined MM subgroup (17% of newly diagnosed patients) with low DNA damage (low genom

100 line genotype never exceeded 5 QALDs for all newly diagnosed people with HIV.

101 A prospective case series of patients with a newly diagnosed renal mass who were referred for surgery

102 al cohort study on consecutive patients with newly diagnosed severe COVID-19.

103 We studied 53 newly diagnosed subjects enrolled in placebo groups of T

104 double-blind, placebo-controlled trial with newly diagnosed T2D patients from 20 centres in China.

105 ween December 2012 and August 2015, patients newly diagnosed with HCC were recruited and provided dem

106 December 31, 2018, 38 Vermont residents were newly diagnosed with HIV-1 infection.

107 y care contractors from >200,000 individuals newly diagnosed with T2D, we predicted five-year risk of

108 S) is an established strategy for women with newly diagnosed, advanced-stage epithelial ovarian cance

109 secutively diagnosed adults (>18 years) with newly diagnosed, untreated mature T-cell or NK lymphomas

110 ing for HIV testing or care, including those newly diagnosed, were eligible and ready for same-day in

111 was 9.2% (54/589, 95%CI: 7.0-11.8%) with 52% newly diagnosed.

112 estigate the impact of COC on CVD risk among newly-diagnosed hypertension patients.

113 During development, newly-differentiated neurons undergo several morphologic

114 In newly differentiating xylem, PRPs are deposited in the r

115 Newly discovered 2D Janus transition metal dichalcogenid

116 newly developed compounds but also compounds newly discovered as contaminants in the environment.

117 nd on a time-stamped benchmark containing 42 newly discovered associations.

118 Our newly discovered bifunctional oxygen-independent pathway

119 cellular niches, as well as in the number of newly discovered compartments.

120 An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has reve

121 of the unique attributes of several of these newly discovered FPs, we expect that Aequorea will, once

122 useful to derive mechanistic hypotheses for newly discovered inhibitors.

123 A newly discovered mechanism that causes the 'Minute' phen

124 orming TMA, carnitine is demethylated by the newly discovered methyltransferase MtcB, sending one-car

125 We conclude that MCUb represents one newly discovered molecular effector at the interface of

126 of human pump orthologs responsible for some newly discovered neurological pathologies.

127 In this review, I discuss newly discovered neuronal circuits in primates that repr

128 WD prions are not the proximate cause of the newly discovered Norwegian CWD cases.

129 Newly discovered oncohistone mutations include lysine-to

130 Our results implicate a newly discovered, multidimensional MAPK7/MMP9 signalling

131 of computational models to incorporate these newly-discovered components.

132 ature of LPHAMS, we characterized one of the newly-discovered heparin-binding proteins, C-type lectin

133 The newly-discovered NSC-BV communication route explains how

134 y mass spectrometry we confirm expression of newly-discovered proteins on the cell surface in vivo.

135 f new bone formation rich in osteoblasts and newly-embedded osteocytes.

136 ent external support-are sufficient to check newly emboldened autocrats.

137 young children are still at high risk to the newly emerged A(H3N2)v viruses.

138 Mainly, it focuses on newly emerged enhanced SPR biosensors towards high-throu

139 and how they inform current research on the newly emerged SARS-CoV-2.

140 rus disease-2019 (COVID-19) is caused by the newly emerged virus severe acute respiratory syndrome co

141 named loci2path that takes advantage of the newly emerged, genome-wide and tissue-specific expressio

142 of these subsets have the characteristics of newly emergent SSCs.

143 We also shed light on the newly emerging approaches for exogenously generating sim

144 Among others, scientists have identified the newly emerging atomically dispersed transition metal (M:

145 and does not confer cross-protection against newly emerging phylogroup II lyssaviruses.

146 Challenges include newly emerging public health concerns across broad and d

147 By contrast, newly emerging shoots display an opposite epigenetic sce

148 However, the generality of this newly emerging, opposite picture has so far not been tes

149 y powerful defense because they can adapt to newly encountered genomes.

150 unity for competition between endogenous and newly-encountered substrates to influence the evolutiona

151 The newly engineered promoter variants form an attractive al

152 uced the annualised rate of formation of new/newly enlarging T2 lesions (52.6%, p<0.001), number of G

153 ve clinic-based dataset with 510 outpatients newly enrolled with diseases of infectious keratitis, no

154 erize epidermal barrier maintenance versus a newly established barrier and functionally identify diff

155 In a newly established in vitro three-dimensional endothelial

156 at is well-conserved across eukaryotes and a newly established member of the higher eukaryotes and pr

157 ful scheduled hemodialysis treatment via the newly exchanged catheter.The patient denied trauma prior

158 FhKT genes (group FhKT1) are secreted by the newly excysted juveniles (NEJs), the stage responsible f

159 We applied this newly expanded program to an assessment of the U.S. Regi

160 the potential allergenicity and toxicity of newly-expressed proteins.

161 Using the newly fertilized Caenorhabditis elegans zygote, we show

162 ER tubule toward another and stays with the newly formed 3-way junction of the ER for a while.

163 ion, cargo engulfment and trafficking of the newly formed autophagic vesicle to the recycling organel

164 inside tooth-extraction wound: proportion of newly formed bone (bone healing/BH), number of cells sta

165 Histological, histometric (percentage of newly formed bone [PNFB], percentage of remaining graft

166 Moreover, the newly formed bone contained higher trabecular number, co

167 Higher percentage area of newly formed bone was observed in CA15 and TCN60 groups

168 ed bone surfaces almost completely filled by newly formed bone, against about 75% in C specimens (P =

169 ng chemogenetic tools to selectively silence newly formed connections in behaviorally recovered anima

170 To assess the chemical composition of this newly formed dentine and to compare its structure with s

171 We show that the newly formed dentine comprises equal carbonate to phosph

172 The newly formed epithelium remains relatively quiescent dur

173 ExBox(+4) , confirming the importance of the newly formed excited-state manifold in TBPCExBox(4+) for

174 on features the remarkable property that the newly formed isomer appears in the excited state rather

175 We found that the newly formed memory was protected from interference when

176 We then tested the newly formed memory's susceptibility to interference.

177 nts at position 5 of the pyrrole ring in the newly formed new biheterocyclic system.

178 cilitating integration of the acentrics into newly formed nuclei.

179 table isotope ratios (n = 1150) to show that newly formed rupture systems crosscut surrounding mounta

180 ication of basaltic rock dust, including via newly formed soil carbonate minerals whose long-term fat

181 high lead fractions likely consist of mostly newly frozen leads that reduce any pre-existing low-leve

182 Thus, our newly generated allele provides novel biological insight

183 synteny conservation across centromeres with newly generated chromosome-level genome assemblies sugge

184 -MS/MS) analyses on brain homogenates of our newly generated knockin mouse expressing a FLAG-tagged v

185 rdelino to a published cancer dataset and to newly generated matched scRNA-seq and exome-seq data fro

186 meningitis virus infection were augmented in newly generated mice lacking LIFR in either CD11c(+) or

187 ascades in prostate tumorigenesis by using a newly generated mouse model in which both murine Met tra

188 beta-catenin in prostate tumorigenesis using newly generated mouse models.

189 ribution data of 1719 genera combined with a newly generated time-calibrated mega-phylogenetic tree.

190 Using these newly generated viruses allowed us to examine the expres

191 Mechanistically, newly generated, circulating neutrophils have lower Ly6G

192 m (PGC) study of schizophrenia yielded seven newly genome-wide significant loci, and we identified an

193 prevalence of measles antibody among 12 349 newly hired HCP between 2009 and 2019.

194 activity of pancreas autoreactive T cells in newly hyperglycemic non-obese diabetic (NOD) mice, prote

195 onoid tissue, and many TAG species have been newly identified (i.e., 18:1-18:2-22:6, 16:0-18:2-20:5,

196 The newly identified and widespread epigenetic marker 6mA DN

197 101 individuals were newly identified as HIV-positive out of 1248 total indiv

198 The newly identified brain SGR produces genomic complementar

199 ance of activated natural killer cells and a newly identified CD3(-)CD68(+)CD4(+)GrB(+) subset.

200 if is present in a number of established and newly identified cohesin ligands, including the cohesin

201 loctadeca-11-enoic acid (11Me-12t-18:1) by a newly identified fatty acid desaturase, UfaD.

202 We further used the newly identified genes to engineer a biosynthetic pathwa

203 rated peptide specificity profiles for three newly identified human TCRs specific for the cancer test

204 -nonene and 2,6-dimethylpyridine, which were newly identified in blue cheese.

205 protein (VCP), an ATPase-associated protein newly identified in the heart, acts as a significant med

206 independent genetic variants, 7 of which are newly identified in this study, conferred risk for cirrh

207 and to characterize the binding mode of the newly identified lead compound.

208 These newly identified markers and mouse models will be an inv

209 Newly identified MDR-related miRNAs (MDRmiRs) enhanced t

210 PIEZO1 and PIEZO2 are newly identified mechanosensitive ion channels that exhi

211 ng Matriptase effects depend on EGFR and the newly identified mediator phospholipase D (PLD), which p

212 search on the specific receptors for several newly identified members of the Paramyxoviridae family t

213 Still, how newly identified neutrophil subsets fit into the bone ma

214 etween groups of DS and NS for extracellular newly identified RAGE binding protein and between CS and

215 tructural characterization disclosed how the newly identified RBD mutations cooperate and thereby enh

216 144, and subsequently examined the role of a newly identified regulator of atherosclerotic burden in

217 cterize both the structure and function of a newly identified RNA thermometer within the ompA transcr

218 A newly identified role for USP11 in ERalpha transcription

219 miR-141-3p/GSN signaling, and targeting this newly identified signaling with small molecules may help

220 of CH24H inhibition was investigated using a newly identified small molecule, soticlestat (TAK-935/OV

221 Mgr2, a newly identified subunit of the TIM23 complex, functions

222 Here, we solved the structure of a newly identified TCR in complex with a clinically releva

223 Also, seven newly-identified anthocyanins including cyanidin 3-xylos

224 Here, we show that loss of Xinbeta, a newly-identified component of ICDs, results in cardiomyo

225 (b) We newly identify a ventroposterior shh pallidal domain rep

226 Exclusion criteria were newly implanted leads, abandoned or epicardial leads, an

227 Newly implicated genes identified in the eQTL analysis i

228 The current systematic review newly included e-cigarettes as a tobacco product.

229 as part of Patient-Reported Outcomes (PROs) newly included in the targets to reach in IBD patients.

230 oncentrations for the period 2009-2014, with newly incorporated concentration-response (C-R) function

231 iscrete frequency infrared microscopy with a newly incorporated spectral region (2,000-2,300 cm(-1)).

232 bally, while in nurse cells Pcl declines and newly induced Scm concentrates PRC2 activity on traditio

233 nt membrane proteins (LMPs), is expressed in newly infected B lymphocytes and in post-transplant lymp

234 ] years; 97% men; 91% white), 57 178 (17.5%) newly initiated statins during the study period.

235 Here, we propose using a newly introduced framework to analyse data from the last

236 individual and global statistics, such as a newly introduced length-weighted asymmetry index and the

237 Through this newly introduced method, we artificially destruct irrele

238 We show that newly introduced mtDNA is stably retained in mtDNA-defic

239 Here, we show that newly introduced nitrogen atoms into the inhibitor scaff

240 t study, we show that phosphorylation of the newly introduced Thr residue explains the functional cha

241 their recombinant heterologous hosts, these newly isolated ZZ phages also targeted OmpC as an altern

242 antiretroviral therapy (ART)-eligible adults newly linking to care at 64 clinics in Zambia between 1

243 trate the ectoperitrophic space in which the newly made peritrophic matrix is synthesized by the prov

244 le root development without inflammation and newly mineralized tissue deposited in the root canal sys

245 onsible for triggering anaphase, to generate newly near-tetraploid cells.

246 These newly opened regions were strongly enriched for the AP-1

247 simulated gastrointestinal digestion using a newly optimised SEC-ICP-MS method.

248 lled patients aged 6 months to 18 years with newly placed PICCs or tunneled lines (TLs).

249 lis infection was defined serologically as a newly positive test with positive confirmatory testing a

250 By providing newly predicted drug-target associations, we uncover nov

251 The newly prepared derivatives showed promising in vitro wou

252 39 351 patients newly prescribed apixaban were propensity score matched

253 propensity score matched to 39 351 patients newly prescribed rivaroxaban.

254 tive study between June 2013 and March 2016, newly presenting patients with RA, patients with other e

255 ions in eight worldwide cities reveal that a newly proposed measure of local dimension explains the e

256 Classical T4 phage engineering and several newly proposed methods are often inefficient and time co

257 This newly recognized bipolar deposition episode has conseque

258 ildren (MIS-C) associated with COVID-19 is a newly recognized condition in children with recent sever

259 le function was used to evaluate the role of newly recognized mechanisms underlying compensation of l

260 A newly recognized multisystem inflammatory syndrome in ch

261 For two of the newly recognized species (P. femoralis, P. percura), the

262 In-vivo, newly recruited cells on the vascular lumen express MC m

263 A group of newly reported antiperovskite nitrides Cu(x) In(1-x) NNi

264 fected at birth and account for up to 95% of newly reported chronic infections in the US.

265 7 across 26 provinces, among which 1,962 are newly reported here.

266 iffered in size (from under 100 to over 1000 newly reported HIV cases among PWID) and in the extent t

267 ve demonstrated this principle in one of our newly reported material, (TMPEA)(2)MnBr(4), where a PLQY

268 We identify 48 genes (25 newly reported) showing significant burden of ultra-rare

269 In addition, comparing the newly resolved structure with those of well-investigated

270 identify genetic factors that differentiate newly resynthesised B. napus, which is inherently unstab

271 t of which were found among individuals from newly sampled ethnolinguistic groups, as well as 62 prev

272 calability for the ever-increasing deluge of newly sequenced genomes.

273 curate tool for detecting microsatellites in newly sequenced genomes.

274 Here, we present 127 newly sequenced transcriptomes and genomes along with ot

275 s some previously known genes, which are now newly shown to have functional evidence in humans as blo

276 g resolution at 22 previously reported and 4 newly significant loci.

277 amined the occurrence of PIPH in outpatients newly starting posaconazole and evaluated differences in

278 lthy and cancer cells can be detected by the newly synthesized bioorthogonal fluorescent probe.

279 receptor alpha (ERalpha)-mediated EA of six newly synthesized bisguaiacols, which differed in the nu

280 ion of cell plates during plant cytokinesis, newly synthesized cell wall polysaccharides are deposite

281 Here we have proven that newly synthesized chiral naphthalene diimide (NDI) deriv

282 Newly synthesized compounds were examined in vitro, and

283 However, forward trafficking of the newly synthesized Cx43 that already reached the Golgi wa

284 nrichment, determine replication rates using newly synthesized DNA strands in human mitochondrial DNA

285 The newly synthesized fused D-A and A-D-A dyes with one or t

286 ion to the proper processing and assembly of newly synthesized histones.

287 A large number of newly synthesized membrane proteins in the endoplasmic r

288 LTM, which relies on the stabilization of a newly synthesized mRNA by a class of RNA binding protein

289 cates that Nup188 populates centrosomes with newly synthesized protein that does not exchange with NP

290 e able to cope with the challenge of folding newly synthesized proteins and refolding those that have

291 We have also identified 431 newly synthesized proteins on isolated IVCs.

292 Newly synthesized proteins were then labeled via 'click

293 Newly synthesized proteins with (15)N contents were dist

294 ion is the correct targeting and delivery of newly synthesized proteins.

295 icking to late endosomes, and exclusion from newly synthesized viral particles.

296 histones (RDH) are required for packaging of newly synthetized DNA into nucleosomes during the S phas

297 1 could lead to the futile re-replication of newly synthetized DNA.

298 Strikingly, Mex67 is essential to stabilize newly transcribed RNA before Xpo1-mediated nuclear expor

299 F.Methods: We performed a multicenter RCT in newly treated patients with IPF.

300 A subset analysis of vaccinated patients newly treated with anti-programmed cell death protein 1